CN106234700A - The medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever and preparation processing method - Google Patents
The medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever and preparation processing method Download PDFInfo
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- CN106234700A CN106234700A CN201610234280.1A CN201610234280A CN106234700A CN 106234700 A CN106234700 A CN 106234700A CN 201610234280 A CN201610234280 A CN 201610234280A CN 106234700 A CN106234700 A CN 106234700A
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- radix
- vitis viniferae
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Abstract
The invention discloses the medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever, be made up of the raw material of following weight portion: Cortex Lycii 5 15 parts, Herba Artemisiae Annuae 25 parts, the Rhizoma Anemarrhenae 5 10 parts, Cortex Moutan 10 16 parts, Radix Achyranthis Bidentatae 25 parts, Radix Pseudostellariae 6 15 parts, Radix Ophiopogonis 5 10 parts, Fructus Schisandrae Chinensis 5 10 parts, 5 10 parts of Talcum, the Radix Astragali 5 10 parts, the Rhizoma Atractylodis Macrocephalae 5 10 parts, Rhizoma Cimicifugae 5 10 parts, Radix Codonopsis 5 10 parts, Radix Angelicae Sinensis 5 10 parts, 5 10 parts of Air Bladder pseudosciaenae seu Acipenser, 10 15 parts of Radix Glycyrrhizae.The invention have the advantage that inventive formulation YIN nourishing, heat clearing away, invigorating qi for ascending treatment low grade fever, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.
Description
Technical field
The present invention relates to the medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever, in particular, relate to a kind of taste
The herb tea formula of cloudy heat clearing away invigorating qi for ascending treatment low grade fever and preparation method thereof technical field.
Background technology
Low grade fever body temperature exceedes normally, but person below 38 DEG C, claim low grade fever.The low grade fever of traditional Chinese medical science indication still includes that patient is subjective certainly
Feverish sensation in the palms and soles, irritable feverish sensation in the chest and the body temperature felt are not above normal a kind of situation.Common manifestation is night fever abating at dawn, or sends out night
Heat is very, hectic fever in the afternoon, feverish sensation in the palms and soles, and vaporization heat of bone is often accompanied by becoming thin, Mental fatigue, weak, indigestion and loss of appetite anorexia, and irritated, red tongue is few
Tongue, the sings and symptoms such as thready and rapid pulse.
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, do not have YIN nourishing, heat clearing away, invigorating qi for ascending treatment low
Heat, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, drop three-hypers, prevent and treat diabetes and anti-cancer, the aspect such as anticancer
Function, it is impossible to releasing the sufferings of client, and traditional herbal tea is by Traditional medicine infusion, flavour of a drug weight mouthfeel is poor, it is impossible to preserve for a long time.
The most not yet occur a kind of in good taste, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen body immunity simultaneously
Beverage.
Summary of the invention
The present invention is directed to the deficiency of existing product, and provide a kind of fresh juice beverage to regulate the effect of human physiological functions,
This beverage have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach,
Cure the disease the medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever simultaneously strengthening the advantage such as body immunity.
The medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever, is made up of the raw material of following weight portion: Cortex Lycii 5-15
Part, Herba Artemisiae Annuae 2-5 part, Rhizoma Anemarrhenae 5-10 part, Cortex Moutan 10-16 part, Radix Achyranthis Bidentatae 2-5 part, Radix Pseudostellariae 6-15 part, 5-10 part Radix Ophiopogonis, the five tastes
Sub-5-10 part, Talcum 5-10 part, Radix Astragali 5-10 part, Rhizoma Atractylodis Macrocephalae 5-10 part, Rhizoma Cimicifugae 5-10 part, Radix Codonopsis 5-10 part, Radix Angelicae Sinensis 5-10 part, fish
Fish glue 5-10 part, Radix Glycyrrhizae 10-15 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel, water are appropriate.
The preparation processing method of the medicated tea of described a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever, comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Radix Codonopsis, Radix Angelicae Sinensis cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, each 2
Hour, merging 2 Radix Codonopsis, Radix Angelicae Sinensis ethanol extracts, stand precipitate with ethanol, filter, filtrate is concentrated into without alcohol taste, and is evaporated to 40
At DEG C, relative density is 1.15-1.35, prepare Radix Codonopsis, Radix Angelicae Sinensis extract standby；
Herba Artemisiae Annuae, Talcum, Radix Astragali mix and blend are put into super micron mill, and super micron mill heating keeps temperature 80 degree 5-6 minute,
Carry out micronizing and obtain the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro mixing fine powders quality 6～the distillation of 8 times
Water, first soaks 10min～15min, pours in volatile oil extractor, and the way of distillation extracts volatile oil 2～4h, it is thus achieved that volatile oil is with super
Microring array fine powder medicinal residues；
Take Cortex Lycii, the Rhizoma Anemarrhenae, Cortex Moutan, Radix Achyranthis Bidentatae, Radix Pseudostellariae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Cimicifugae, Air Bladder pseudosciaenae seu Acipenser, Radix Glycyrrhizae, mix homogeneously
After adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine
Block, extracts freezing medicine block and ultra micro mixing fine powders medicinal residues boiling 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-
120 DEG C, carry out infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；The
Adding 6-10 times amount water for three times, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, adds
Enter Radix Codonopsis, the extract of Radix Angelicae Sinensis and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute,
Make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Further: step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion be 10:0.2～0.8:5～10:0.5.
Cortex Lycii, removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.
Herba Artemisiae Annuae fringe, yin nourishing, heat clearing away, QI invigorating. it is applicable to hectic fever due to YIN-deficiency interior-heat, or cold and heat are like malaria, or hot towards cool dusk.
The Rhizoma Anemarrhenae, returns lung, stomach, kidney channel.Clearing away heat-fire is nourshing Yin and drynsessmoistening prescription.Calentura excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat disappears
Yearningly, dryness of the intestine constipation.
Cortex Moutan, pungent, bitter, be slightly cold.GUIXIN, liver, kidney channel.For the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, there is clearing away heat and cooling blood effect.
Radix Achyranthis Bidentatae, dissipating blood stasis blood, subduing inflammation are used in life.
Radix Pseudostellariae, mends strengthening spleen and lung, supplementing QI for promoting the production of body fluid, controls cough due to deficiency of the lung, insufficiency of the spleen lack of appetite, cardiopalmus, palpitation with a distress feeling, edema, quench one's thirst, spirit
Tired.
Radix Ophiopogonis, sweet in the mouth, micro-hardship, cold nature, return stomach, lung, heart channel, have nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the merit of the relieving restlessness that clears away heart-fire
Effect.
Fructus Schisandrae Chinensis, supports the five internal organs, heat extraction, flesh in raw the moon, main QI invigorating, cough with dyspnea, the thin degree of impairment caused by overstrain, tonifying for the deficiency.
Talcum, clearing away fire and eliminating phlegm, dampness removing is relieved summer heat, and restores menstrual flow and invigorates blood circulation, and antidiarrheal dysentery is vomitted, consumer edema fire-toxin.
The Radix Astragali, returns lung, spleen, liver, kidney channel.Enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and
Wide antibacterial action.
The Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature;Return spleen, stomach warp;Fragrance matter is soft, can rise and can drop, keep and do not walk to have invigorating the spleen and benefiting QI,
Dampness diuretic, strengthening superficial resistance to stop perspiration.
Rhizoma Cimicifugae, pungent and cold medicine for relieving the exterior syndrome.Meridian distribution of property and flavor: sweet, pungent, be slightly cold.Return spleen, stomach, lung, large intestine channel.For delivering rash,
Heat-clearing and toxic substances removing, rises and lifts yang-energy.
Radix Codonopsis, sweet, flat.Invigorating the spleen and replenishing QI, stomach function regulating promotes the production of body fluid, expelling phlegm for arresting cough, for weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength,
Lack of appetite, thirsty.
Radix Angelicae Sinensis, sweet, pungent, warm, return liver, the heart, spleen channel, enrich blood；Invigorate blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.
Air Bladder pseudosciaenae seu Acipenser, sweet, flat, nontoxic.Sweet in the mouth, temperature.Enter kidney.The kidney invigorating and essence nourishing, nourishes muscle arteries and veins, hemostasis, dissipating blood stasis, detumescence, controls kidney
Empty spermatorrhea.
Radix Glycyrrhizae, and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.
Fructus Vitis viniferae is the most delicious and tasty, and nutritive value is the highest, containing mineral calcium, potassium, phosphorus, ferrum and multiple in Fructus Vitis viniferae
Vitamin B1, vitamin B2, vitamin B6, vitamin C and Citrin etc., possibly together with the aminoacid of multiple needed by human body, multiple
Fruit acid contributes to digestion, suitably eats a little Fructus Vitis viniferae more, can be good for Pi stomach function regulating, and to neurasthenia, overfatigue is of great advantage and has.
Being share by the natural tradition medicinal and edible Chinese medicine above with multiple health care, YIN nourishing, heat clearing away, invigorating qi for ascending are controlled
Treat low grade fever, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.Each by great many of experiments screening
The proportioning of component, scientific and reasonable；And whole preparation technology is rationally and extract drugs rate efficiency is high, can retain in raw material well
Effective ingredient, do not bring any impurity, and sweet mouthfeel into, have no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines
Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported
Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax
Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong anti-oxidation, resist
Suddenly change, alleviate the function such as hepatosis, protection cardiovascular；
3, add in Cortex Lycii, the Rhizoma Anemarrhenae, Cortex Moutan, Radix Achyranthis Bidentatae, Radix Pseudostellariae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Cimicifugae, Air Bladder pseudosciaenae seu Acipenser, Radix Glycyrrhizae etc.
Medical herbs has YIN nourishing, heat clearing away, invigorating qi for ascending treatment low grade fever, improves body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, resists
The functions such as fatigue.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has
The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and
Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1-
2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
The medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever, is made up of the raw material of following weight portion: Cortex Lycii 8 parts, Herba Artemisiae Annuae 3
Part, the Rhizoma Anemarrhenae 8 parts, Cortex Moutan 12 parts, Radix Achyranthis Bidentatae 5 parts, Radix Pseudostellariae 8 parts, Radix Ophiopogonis 8 parts, Fructus Schisandrae Chinensis 8 parts, 8 parts of Talcum, the Radix Astragali 8 parts, white
Art 8 parts, Rhizoma Cimicifugae 8 parts, Radix Codonopsis 8 parts, Radix Angelicae Sinensis 8 parts, 8 parts of Air Bladder pseudosciaenae seu Acipenser, 12 parts of Radix Glycyrrhizae, new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water
In right amount.
The preparation processing method of the medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever, described preparation method includes following
Step；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
Fresh for the Herba Dendrobii cleaned up bar is put into microwave oven by B, keeps temperature 50-60 DEG C, carries out heating 10 minutes, further take out
Put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content 52 of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
DEG C Chinese liquor, time 15min, the rotating speed of juice extractor is 30r/s；After standing 10 minutes, add the steaming of Herba Dendrobii fresh bar weight 2.5 times
Distilled water, for the second time juice extractor time 15min, juice extractor rotating speed is 80r/s, stands 10min；After carry out third time squeeze the juice, add
The distilled water of Herba Dendrobii fresh bar weight 3-5 times, time 30min, juice extractor rotating speed is 150r/s, by fresh for Herba Dendrobii bar juice and fiber mistake
Filter separate, make the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, broken cell rate reaches more than 80%, obtain new fresh Herba Dendrobii juice and
Herba Dendrobii fresh bar fiber；Again new fresh grape is put into after the warm water of 55 DEG C cleans up, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated
Stand-by；After new fresh grape cleans up, put into reach in freezer ,-10 ~-20 DEG C of freezings 10 minutes, make Fructus Vitis viniferae freeze, take out certainly
After so thawing, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 120 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 6 times of weight, stirring is smashed to 100 mesh, 30-35 DEG C of temperature
Degree lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby；Extract the Fructus Vitis viniferae after Matrix Solution
It is the cellulase of 0.5-0.7% that skin and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, keeps
35 DEG C, water soluble dietary fiber can be extracted after 24h enzymolysis further, water soluble dietary fiber is added Matrix Solution and obtains
Matrix Solution II；Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to protection human body is from the damage of free radical, it is possible to enhancing blood vessel elasticity,
Lax blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong antioxygen
Change, mutation, alleviate hepatosis, protection function, Pericarpium Vitis viniferae and the Herba Dendrobii fresh bar fiber such as cardiovascular together with stir smash through
Anthocyanidin mentioned by hydromel, can protect the quality of anthocyanidin while farthest extracting anthocyanidin.By water solublity meals
Food fiber adds Matrix Solution and obtains Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged
External；Adsorbing various metabolic waste, be allowed to normally excrete, the comprehensive utilization value improving Herba Dendrobii improves human body centering simultaneously
The absorption of medicine composition.
E, take mix homogeneously after Radix Codonopsis, Radix Angelicae Sinensis cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, often
Secondary 2 hours, merging 2 Radix Codonopsis, Radix Angelicae Sinensis ethanol extracts, stand precipitate with ethanol, filter, filtrate is concentrated into without alcohol taste, and concentrating under reduced pressure
At 40 DEG C, relative density is 1.15-1.35, prepare Radix Codonopsis, Radix Angelicae Sinensis extract standby；
Herba Artemisiae Annuae, Talcum, Radix Astragali mix and blend are put into super micron mill, and super micron mill heating keeps temperature 80 degree 5-6 minute,
Carry out micronizing and obtain the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro mixing fine powders quality 6～the distillation of 8 times
Water, first soaks 10min～15min, pours in volatile oil extractor, and the way of distillation extracts volatile oil 2～4h, it is thus achieved that volatile oil is with super
Microring array fine powder medicinal residues；
Take Cortex Lycii, the Rhizoma Anemarrhenae, Cortex Moutan, Radix Achyranthis Bidentatae, Radix Pseudostellariae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Cimicifugae, Air Bladder pseudosciaenae seu Acipenser, Radix Glycyrrhizae, mix homogeneously
After adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine
Block, extracts freezing medicine block and ultra micro mixing fine powders medicinal residues boiling 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-
120 DEG C, carry out infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；The
Adding 6-10 times amount water for three times, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, adds
Enter Radix Codonopsis, the extract of Radix Angelicae Sinensis and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 120 DEG C, 1-2 minute, put into material-compound tank；Taking Matrix Solution II through mesh number is
Material-compound tank is put into after the fine filter filter of 100 mesh；Take Matrix Solution III again and put into dispensing after the fine filter filter that mesh number is 60 mesh
In tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；Supercritical extraction can be
Extract under room temperature 37 DEG C and CO2 gas blanket, effectively prevent oxidation and the loss of heat-sensitive substance.Therefore,
The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the easy material being pyrolyzed the lowest
Extract under its boiling temperature；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, and described material-compound tank endobasal-body solution I, matrix are molten
Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5.Sealing through bottle capper loads in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning,
Carrying and drink conveniently, the shelf-life is up to 1-2.
Embodiment 2
The medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever, is made up of the raw material of following weight portion: Cortex Lycii 5 parts, Herba Artemisiae Annuae 2
Part, the Rhizoma Anemarrhenae 5 parts, Cortex Moutan 10 parts, Radix Achyranthis Bidentatae 2 parts, Radix Pseudostellariae 6 parts, Radix Ophiopogonis 5 parts, Fructus Schisandrae Chinensis 5 parts, 5 parts of Talcum, the Radix Astragali 5 parts, white
Art 5 parts, Rhizoma Cimicifugae 5 parts, Radix Codonopsis 5 parts, Radix Angelicae Sinensis 5 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, 10 parts of Radix Glycyrrhizae, new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Mel, water
In right amount.Processing method is with embodiment 1.
Embodiment 3
The medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever, is made up of the raw material of following weight portion: Cortex Lycii 15 parts, Herba Artemisiae Annuae
5 parts, the Rhizoma Anemarrhenae 10 parts, Cortex Moutan 16 parts, Radix Achyranthis Bidentatae 5 parts, Radix Pseudostellariae 15 parts, Radix Ophiopogonis 10 parts, Fructus Schisandrae Chinensis 10 parts, 10 parts of Talcum, the Radix Astragali
10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Rhizoma Cimicifugae 10 parts, Radix Codonopsis 10 parts, Radix Angelicae Sinensis 10 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, 15 parts of Radix Glycyrrhizae, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae
20 parts, Mel, water appropriate.Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding
Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days；In 7 days, mice is without death, OK
For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception,
Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not
See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that two kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100,
50g；Experimental mouse is randomly divided into two groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal
General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart,
The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach；
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no
Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach
Deng the most significant change, it is understood that through proved by pathology, two kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is
Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 7 days
3. number is drunk: 50 people
4. drinking method: 500mL for each person every day
5. index: substantially hectic fever in the afternoon, feverish sensation in the palms and soles, vaporization heat of bone after drinking, is often accompanied by becoming thin, and Mental fatigue is weak, indigestion and loss of appetite detests
Food, irritated, red tongue lacks the transference cures such as tongue, tired mind, inappetence, and mouthfeel is the most sour-sweet for effective；Afternoon tide after drinking
Heat, feverish sensation in the palms and soles, vaporization heat of bone, it is often accompanied by becoming thin, Mental fatigue, weak, indigestion and loss of appetite anorexia, irritated, red tongue few tongue, tired mind, food
It is intended to depressed remission of Denging, and mouthfeel is the most sour-sweet, be designated as effectively.It is invalid to be then designated as without obvious comfort after drinking.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried
The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially
Increase comfort.
The each embodiment of table 1 drinks effect research table
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Embodiment 1 | 44%(22) | 54%(27) | 2%(1) |
| Embodiment 2 | 42%(21) | 56%(28) | 2%(1) |
| Embodiment 3 | 42%(21) | 56%(28) | 2%(1) |
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling
Method；The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 4 | 36%(18) | 40%(20) | 24%(12) |
| Comparative example 5 | 40%(20) | 40%(20) | 20%(10) |
| Comparative example 6 | 46%(23) | 34%(17) | 20%(10) |
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1
The preparation processing method of step E；The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 7 | 32%(16) | 56%(28) | 12%(6) |
| Comparative example 8 | 28%(14) | 52%(31) | 10%(5) |
| Comparative example 9 | 36%(18) | 52%(26) | 12%(6) |
Embodiment contrast groups C
The processing method of comparative example 10,11,12 respectively corresponding embodiment 1,2,3 and formula, different be formula in
Without Air Bladder pseudosciaenae seu Acipenser composition；The investigation method of using method and using effect is with above.
Table 4 embodiment contrast groups C drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 10 | 44%(22) | 46%(23) | 10%(5) |
| Comparative example 11 | 38%(19) | 50%(25) | 12%(6) |
| Comparative example 12 | 40%(20) | 48%(24) | 12%(6) |
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3；This shows Chinese crude drug formula of the present invention
And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine
Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally
The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc.
Function, strengthens immune system ability；Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously
The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology
Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional
Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step
The preparation processing method of rapid E has had significant raising than traditional boiling method, the extraction degree of active ingredient.
Table 1 is compared with table 4:
The formula of embodiment contrast groups C does not contains Air Bladder pseudosciaenae seu Acipenser, and the invalid number of embodiment contrast groups C is 5 times of left sides of embodiment 1,2,3
Right；And effective percentage number has and has declined；Show Air Bladder pseudosciaenae seu Acipenser serve in formula collaborative and priming return through effect, Air Bladder pseudosciaenae seu Acipenser should
Unexpected technique effect is achieved by effect.
In sum, the medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever that the present invention provides, YIN nourishing, heat clearing away, benefit
Gas lift carry treatment low grade fever, there is sour-sweet mouthfeel, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, fall three-hypers,
Prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful.And all raw materials is all from medicine-food two-purpose natural plants, nontoxic secondary make
With.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (7)
1. the medicated tea of a nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever, it is characterised in that be made up of the raw material of following weight portion: ground
Cortex Lycii 5-15 part, Herba Artemisiae Annuae 2-5 part, Rhizoma Anemarrhenae 5-10 part, Cortex Moutan 10-16 part, Radix Achyranthis Bidentatae 2-5 part, Radix Pseudostellariae 6-15 part, 5-10 Radix Ophiopogonis
Part, Fructus Schisandrae Chinensis 5-10 part, Talcum 5-10 part, Radix Astragali 5-10 part, Rhizoma Atractylodis Macrocephalae 5-10 part, Rhizoma Cimicifugae 5-10 part, Radix Codonopsis 5-10 part, Radix Angelicae Sinensis 5-
10 parts, Air Bladder pseudosciaenae seu Acipenser 5-10 part, Radix Glycyrrhizae 10-15 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel, water appropriate.
The medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending the most according to claim 1 treatment low grade fever, it is characterised in that by following
The raw material of weight portion is made: Cortex Lycii 8 parts, Herba Artemisiae Annuae 3 parts, the Rhizoma Anemarrhenae 8 parts, Cortex Moutan 12 parts, Radix Achyranthis Bidentatae 5 parts, Radix Pseudostellariae 8 parts, Radix Ophiopogonis 8
Part, Fructus Schisandrae Chinensis 8 parts, 8 parts of Talcum, the Radix Astragali 8 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, Rhizoma Cimicifugae 8 parts, Radix Codonopsis 8 parts, Radix Angelicae Sinensis 8 parts, 8 parts of Air Bladder pseudosciaenae seu Acipenser, Radix Glycyrrhizae 12
Part, new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water are appropriate.
The medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending the most according to claim 1 treatment low grade fever, it is characterised in that by following
The raw material of weight portion is made: Cortex Lycii 5 parts, Herba Artemisiae Annuae 2 parts, the Rhizoma Anemarrhenae 5 parts, Cortex Moutan 10 parts, Radix Achyranthis Bidentatae 2 parts, Radix Pseudostellariae 6 parts, Radix Ophiopogonis 5
Part, Fructus Schisandrae Chinensis 5 parts, 5 parts of Talcum, the Radix Astragali 5 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Rhizoma Cimicifugae 5 parts, Radix Codonopsis 5 parts, Radix Angelicae Sinensis 5 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, Radix Glycyrrhizae 10
Part, new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Mel, water are appropriate.
The medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending the most according to claim 1 treatment low grade fever, it is characterised in that by following
The raw material of weight portion is made: Cortex Lycii 15 parts, Herba Artemisiae Annuae 5 parts, the Rhizoma Anemarrhenae 10 parts, Cortex Moutan 16 parts, Radix Achyranthis Bidentatae 5 parts, Radix Pseudostellariae 15 parts, wheat
Winter 10 parts, Fructus Schisandrae Chinensis 10 parts, 10 parts of Talcum, the Radix Astragali 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Rhizoma Cimicifugae 10 parts, Radix Codonopsis 10 parts, Radix Angelicae Sinensis 10 parts, Air Bladder pseudosciaenae seu Acipenser
10 parts, 15 parts of Radix Glycyrrhizae, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Mel, water appropriate.
5. the preparation processing method of the medicated tea of a nourishing YIN and clearing away heat invigorating qi for ascending treatment low grade fever, it is characterised in that include following step
Suddenly；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Radix Codonopsis, Radix Angelicae Sinensis cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, each 2
Hour, merging 2 Radix Codonopsis, Radix Angelicae Sinensis ethanol extracts, stand precipitate with ethanol, filter, filtrate is concentrated into without alcohol taste, and is evaporated to 40
At DEG C, relative density is 1.15-1.35, prepare Radix Codonopsis, Radix Angelicae Sinensis extract standby；
Herba Artemisiae Annuae, Talcum, Radix Astragali mix and blend are put into super micron mill, and super micron mill heating keeps temperature 80 degree 5-6 minute,
Carry out micronizing and obtain the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro mixing fine powders quality 6～the distillation of 8 times
Water, first soaks 10min～15min, pours in volatile oil extractor, and the way of distillation extracts volatile oil 2～4h, it is thus achieved that volatile oil is with super
Microring array fine powder medicinal residues；
Take Cortex Lycii, the Rhizoma Anemarrhenae, Cortex Moutan, Radix Achyranthis Bidentatae, Radix Pseudostellariae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Cimicifugae, Air Bladder pseudosciaenae seu Acipenser, Radix Glycyrrhizae, mix homogeneously
After adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine
Block, extracts freezing medicine block and ultra micro mixing fine powders medicinal residues boiling 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-
120 DEG C, carry out infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；The
Adding 6-10 times amount water for three times, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, adds
Enter Radix Codonopsis, the extract of Radix Angelicae Sinensis and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
The preparation processing method of the medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending the most according to claim 5 treatment low grade fever, its
It is characterised by, step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute, make
Fructus Vitis viniferae freezes, and after taking out nature defrosting, then carries out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
The preparation processing method of the medicated tea of a kind of nourishing YIN and clearing away heat invigorating qi for ascending the most according to claim 5 treatment low grade fever, its
Be characterised by, step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, the weight of Oleum Vitis viniferae
Proportioning is 10:0.2～0.8:5～10:0.5.
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| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
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|---|---|---|---|---|
| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
Non-Patent Citations (2)
| Title |
|---|
| 宋芳等: "超临界二氧化碳萃取葡萄籽油及其脂肪酸的分析", 《中国食品工业》 * |
| 李文亮，等: "《千家妙方 上册》", 31 July 1982, 战士出版社 * |
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Application publication date: 20161221 |