CN106173033A - A kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea and preparation processing method - Google Patents
A kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea and preparation processing method Download PDFInfo
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- CN106173033A CN106173033A CN201610234275.0A CN201610234275A CN106173033A CN 106173033 A CN106173033 A CN 106173033A CN 201610234275 A CN201610234275 A CN 201610234275A CN 106173033 A CN106173033 A CN 106173033A
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Classifications
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Abstract
The invention discloses a kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea of the present invention, be made up of the raw material of following weight portion: 5 15 parts of the Radix Rehmanniae, Caulis Akebiae 5 12 parts, 39 parts of Folium Bambusae, poultry 5 12 parts, Folium Pyrrosiae 5 10 parts, Spora Lygodii 10 16 parts, Rhizoma Imperatae 5 15 parts, Herba Taraxaci 6 15 parts, Herba Houttuyniae 5 10 parts, Radix Astragali 5 10 parts, the Rhizoma Atractylodis Macrocephalae 5 10 parts, Cortex Mori 5 10 parts, Pericarpium Arecae 5 10 parts, Lignum Aquilariae Resinatum 5 10 parts, Stigma Maydis 5 10 parts, Pericarpium Citri Reticulatae 5 10 parts.The invention have the advantage that the hemostasis of inventive formulation clearing away heat and promoting diuresis, diuresis of inducing sweat, circulation of qi promoting disappear water treatment acute nephritis, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.
Description
Technical field
The present invention relates to a kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea, in particular, relate to a kind of clearing away heat and promoting diuresis
Treatment acute nephritis herb tea formula and preparation method thereof technical field.
Background technology
Acute nephritis medicine is one group of primary glomerulonephritis with acute nephritic syndrome as main clinical manifestation.It is special
Point is Acute onset, hematuria, albuminuria, edema and hypertension, can accompany transient azotemia, has spontaneous recovery tendency.It is common in
After streptococcal infection, and other antibacterials, virus and parasitic infection also can cause, damp invasion of lower energizer, the kidney bladder deficiency of YIN, wet tired in
Jiao, affection of exogenous wind-cold, fever with aversion to cold, dysuria, hematuria dysurea.
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, and does not have clearing away heat and promoting diuresis hemostasis, diuresis of inducing sweat, circulation of qi promoting
The water that disappears treatment acute nephritis, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, drop three-hypers, prevent and treat diabetes and
Anti-cancer, the function of the aspect such as anticancer, it is impossible to release the sufferings of client, and traditional herbal tea is by Traditional medicine infusion, flavour of a drug weight mouthfeel
Difference, it is impossible to preserve for a long time.The most not yet occur a kind of in good taste, improve self and increase the wriggling of the intestines and stomach, cure the disease simultaneously
Strengthen the beverage of body immunity.
Summary of the invention
The present invention is directed to the deficiency of existing product, and provide a kind of fresh juice beverage to regulate the effect of human physiological functions,
This beverage have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach,
Cure the disease and strengthen a kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea of the advantages such as body immunity simultaneously.
A kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea, is made up of the raw material of following weight portion: Radix Rehmanniae 5-15 part, Caulis Akebiae 5-
12 parts, Folium Bambusae 3-9 part, poultry 5-12 part, Folium Pyrrosiae 5-10 part, Spora Lygodii 10-16 part, Rhizoma Imperatae 5-15 part, Herba Taraxaci 6-15 part,
Herba Houttuyniae 5-10 part, Radix Astragali 5-10 part, Rhizoma Atractylodis Macrocephalae 5-10 part, Cortex Mori 5-10 part, Pericarpium Arecae 5-10 part, Lignum Aquilariae Resinatum 5-10 part, Semen Maydis
Must 5-10 part, Pericarpium Citri Reticulatae 5-10 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel, water appropriate.
The preparation processing method of described a kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea, comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Cortex Mori, Pericarpium Arecae, Lignum Aquilariae Resinatum, Stigma Maydis, Pericarpium Citri Reticulatae cleaning and sterilizing, respectively with 6 times of weight 85% mole
Ratio ethanol extraction 2 times, each 2 hours, merges 2 Cortex Mori, Pericarpium Arecae, Lignum Aquilariae Resinatum, Stigma Maydis, Pericarpium Citri Reticulatae ethanol extracts, stands alcohol
Heavy, to filter, filtrate is concentrated into without alcohol taste, and to be evaporated to relative density at 40 DEG C be 1.15-1.35, prepared Cortex Mori, big abdomen
Skin, Lignum Aquilariae Resinatum, Stigma Maydis, Pericarpium Citri Reticulatae extract standby；
Rhizoma Imperatae, Herba Taraxaci, Herba Houttuyniae, Radix Astragali, the Rhizoma Atractylodis Macrocephalae being closed stirring and put into super micron mill, super micron mill heating keeps
Temperature 80 degree 5-6 minute, carries out micronizing and obtains the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro mixing fine powders
Quality 6～the distilled water of 8 times, first soak 10min～15min, pour in volatile oil extractor, the way of distillation extract volatile oil 2～
4h, it is thus achieved that volatile oil and ultra micro mixing fine powders medicinal residues；
Take the Radix Rehmanniae, Caulis Akebiae, Folium Bambusae, poultry, Folium Pyrrosiae, Spora Lygodii, Air Bladder pseudosciaenae seu Acipenser, after mix homogeneously adds 30-60 DEG C of warm water soaking 10 minutes,
Put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine block, by freezing medicine block and ultra micro mixing fine powders
Medicinal residues boiling is extracted 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out infusion 10-20 minute；The
Secondary adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times amount water, and temperature keeps
120-150 DEG C, carry out infusion 30 minutes, filter, be concentrated into the 1/2 of original volume, add Cortex Mori, Pericarpium Arecae, Lignum Aquilariae Resinatum, Semen Maydis
Palpus, the extract of Pericarpium Citri Reticulatae and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute,
Make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Further: step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion be 10:0.2～0.8:5～10:0.5.
The Radix Rehmanniae, sweet in the mouth, cold.Hemopoietic removing heat from blood, cures mainly folding and falls, exhausted muscle, damaging the spleen and stomach, by arthralgia due to stagnation of blood, fills out bone marrow, long muscle.
Caulis Akebiae, pathogenic fire purging row water, promoting blood circulation, control hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia.
Folium Bambusae, bitter, sweet, it is slightly cold, nontoxic, enter the heart, lung, flesh three warp, cool heart channel, benefit vigour, heat extraction, slow spleen.
Poultry, bitter, flat, enter stomach, bladder warp, clearing away heat and promoting diuresis is treating stranguria, inducing diuresis for treating stranguria syndrome: for acute cystitis, urethritis it
The puckery pain of oliguria.
Folium Pyrrosiae, cold nature, sweet in the mouth, hardship.Feeble QI, the micro-puckery hardship of taste.Can be with inducing diuresis for treating stranguria syndrome, clearing away heat to stop bleeding.
Spora Lygodii, sweet light diuresis, cold can heat clearing away, its property declines, and kind clear small intestinal, damp-heat in the urinary bladder, merit patent water, for controlling stranguria
Key medicine.
Rhizoma Imperatae, returns lung, stomach, bladder warp.Cooling blood for hemostasis, clearing away heat and promoting diuresis.
Herba Taraxaci, heat-clearing and toxic substances removing, for heat toxin syndrome, especially it is apt to removing heat from the liver, treats liver-heat conjunctival congestion and swelling pain.
Herba Houttuyniae, acrid in the mouth cold in nature, enter liver lung two warp, there is effect of heat-clearing and toxic substances removing line water detumescence promoting tissue regeneration by removing blood stasis cough-relieving.
Radix Astragali, sweet in the mouth, tepor, there is invigorating QI to consolidate the body surface resistance, hold in the palm skin ulcer granulation promoting, effect of diuretic.
The Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature;Return spleen, stomach warp;Fragrance matter is soft, can rise and can drop, keep and do not walk to have invigorating the spleen and benefiting QI,
Dampness diuretic, strengthening superficial resistance to stop perspiration.
Cortex Mori, sweet in the mouth, micro-hardship, returns lung, spleen channel, dyspnea and cough due to lung-heat, and diseases caused by retention of fluid stops lung, distension dyspnea with rapid respiration, outstanding kind purte the white and relieving asthma
Coughing, control lung-heat cough with asthma, expectorant is thick and yellow.
Pericarpium Arecae, has therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, effect of line water detumescence.
Lignum Aquilariae Resinatum, acrid in the mouth, hardship, warm in nature；Return spleen, stomach, kidney channel;Gas perfume (or spice) row dissipates, and drops and can rise；There is circulation of qi promoting warming middle-JIAO to send down the adverse QI, warm
Effect of kidney helping inspiration to relieve asthma.
Stigma Maydis, the health-care effect such as diuresis, blood pressure lowering, function of gallbladder promoting and hemostasis, nephritis, hepatitis etc. are had good therapeutical effect.
Pericarpium Citri Reticulatae, bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.
Fructus Vitis viniferae is the most delicious and tasty, and nutritive value is the highest, containing mineral calcium, potassium, phosphorus, ferrum and multiple in Fructus Vitis viniferae
Vitamin B1, vitamin B2, vitamin B6, vitamin C and Citrin etc., possibly together with the aminoacid of multiple needed by human body, multiple
Fruit acid contributes to digestion, suitably eats a little Fructus Vitis viniferae more, can be good for Pi stomach function regulating, and to neurasthenia, overfatigue is of great advantage and has.
The natural tradition medicinal and edible Chinese medicine above with multiple health care is share, clearing away heat and promoting diuresis hemostasis, profit of inducing sweat
Urinate, circulation of qi promoting disappears water treatment acute nephritis, improves body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.Logical
Cross the proportioning of each component of a large amount of experiment screening, scientific and reasonable；And whole preparation technology is rationally and extract drugs rate efficiency is high, energy
Retain the effective ingredient in raw material well, do not bring any impurity, and sweet mouthfeel into, have no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines
Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported
Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax
Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong anti-oxidation, resist
Suddenly change, alleviate the function such as hepatosis, protection cardiovascular；
3, add the Chinese herbal medicine such as the Radix Rehmanniae, Caulis Akebiae, Folium Bambusae, poultry, Folium Pyrrosiae, Spora Lygodii and there is clearing away heat and promoting diuresis hemostasis, diuresis of inducing sweat, OK
Gas disappears water treatment acute nephritis, improves the function such as body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, resisting fatigue.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has
The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and
Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1-
2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
A kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea, is made up of the raw material of following weight portion: 10 parts of the Radix Rehmanniae, Caulis Akebiae 10 parts, bamboo
8 parts of leaf, poultry 10 parts, Folium Pyrrosiae 8 parts, Spora Lygodii 12 parts, Rhizoma Imperatae 12 parts, Herba Taraxaci 12 parts, Herba Houttuyniae 8 parts, Radix Astragali 8 parts,
The Rhizoma Atractylodis Macrocephalae 8 parts, Cortex Mori 8 parts, Pericarpium Arecae 8 parts, Lignum Aquilariae Resinatum 8 parts, Stigma Maydis 8 parts, Pericarpium Citri Reticulatae 8 parts, 8 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae
15 parts, Mel, water appropriate.
The preparation processing method of a kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea, described preparation method comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
Fresh for the Herba Dendrobii cleaned up bar is put into microwave oven by B, keeps temperature 50-60 DEG C, carries out heating 10 minutes, further take out
Put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content 52 of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
DEG C Chinese liquor, time 15min, the rotating speed of juice extractor is 30r/s；After standing 10 minutes, add the steaming of Herba Dendrobii fresh bar weight 2.5 times
Distilled water, for the second time juice extractor time 15min, juice extractor rotating speed is 80r/s, stands 10min；After carry out third time squeeze the juice, add
The distilled water of Herba Dendrobii fresh bar weight 3-5 times, time 30min, juice extractor rotating speed is 150r/s, by fresh for Herba Dendrobii bar juice and fiber mistake
Filter separate, make the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, broken cell rate reaches more than 80%, obtain new fresh Herba Dendrobii juice and
Herba Dendrobii fresh bar fiber；Again new fresh grape is put into after the warm water of 55 DEG C cleans up, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated
Stand-by；After new fresh grape cleans up, put into reach in freezer ,-10 ~-20 DEG C of freezings 10 minutes, make Fructus Vitis viniferae freeze, take out certainly
After so thawing, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 120 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 6 times of weight, stirring is smashed to 100 mesh, 30-35 DEG C of temperature
Degree lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby；Extract the Fructus Vitis viniferae after Matrix Solution
It is the cellulase of 0.5-0.7% that skin and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, keeps
35 DEG C, water soluble dietary fiber can be extracted after 24h enzymolysis further, water soluble dietary fiber is added Matrix Solution and obtains
Matrix Solution II；Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to protection human body is from the damage of free radical, it is possible to enhancing blood vessel elasticity,
Lax blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong antioxygen
Change, mutation, alleviate hepatosis, protection function, Pericarpium Vitis viniferae and the Herba Dendrobii fresh bar fiber such as cardiovascular together with stir smash through
Anthocyanidin mentioned by hydromel, can protect the quality of anthocyanidin while farthest extracting anthocyanidin.By water solublity meals
Food fiber adds Matrix Solution and obtains Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged
External；Adsorbing various metabolic waste, be allowed to normally excrete, the comprehensive utilization value improving Herba Dendrobii improves human body centering simultaneously
The absorption of medicine composition.
E, take mix homogeneously after Cortex Mori, Pericarpium Arecae, Lignum Aquilariae Resinatum, Stigma Maydis, Pericarpium Citri Reticulatae cleaning and sterilizing, respectively with 6 times of weight 85%
Mol ratio ethanol extraction 2 times, each 2 hours, merges 2 Cortex Mori, Pericarpium Arecae, Lignum Aquilariae Resinatum, Stigma Maydis, Pericarpium Citri Reticulatae ethanol extracts, quiet
Putting precipitate with ethanol, filter, filtrate is concentrated into without alcohol taste, and to be evaporated to relative density at 40 DEG C be 1.15-1.35, prepared Cortex Mori,
Pericarpium Arecae, Lignum Aquilariae Resinatum, Stigma Maydis, Pericarpium Citri Reticulatae extract standby；
Rhizoma Imperatae, Herba Taraxaci, Herba Houttuyniae, Radix Astragali, the Rhizoma Atractylodis Macrocephalae being closed stirring and put into super micron mill, super micron mill heating keeps
Temperature 80 degree 5-6 minute, carries out micronizing and obtains the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro mixing fine powders
Quality 6～the distilled water of 8 times, first soak 10min～15min, pour in volatile oil extractor, the way of distillation extract volatile oil 2～
4h, it is thus achieved that volatile oil and ultra micro mixing fine powders medicinal residues；
Take the Radix Rehmanniae, Caulis Akebiae, Folium Bambusae, poultry, Folium Pyrrosiae, Spora Lygodii, Air Bladder pseudosciaenae seu Acipenser, after mix homogeneously adds 30-60 DEG C of warm water soaking 10 minutes,
Put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine block, by freezing medicine block and ultra micro mixing fine powders
Medicinal residues boiling is extracted 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out infusion 10-20 minute；The
Secondary adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times amount water, and temperature keeps
120-150 DEG C, carry out infusion 30 minutes, filter, be concentrated into the 1/2 of original volume, add Cortex Mori, Pericarpium Arecae, Lignum Aquilariae Resinatum, Semen Maydis
Palpus, the extract of Pericarpium Citri Reticulatae and volatile oil, obtain Matrix Solution III standby；
The hard to bear medicine boiled is pulverized and improves its extract drugs efficiency, make whole formula drug effect farthest be utilized.
F, take Matrix Solution I through instantaneous high-temperature 120 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；Supercritical extraction can be
Extract under room temperature 37 DEG C and CO2 gas blanket, effectively prevent oxidation and the loss of heat-sensitive substance.Therefore,
The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the easy material being pyrolyzed the lowest
Extract under its boiling temperature；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, and described material-compound tank endobasal-body solution I, matrix are molten
Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5.Sealing through bottle capper loads in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning,
Carrying and drink conveniently, the shelf-life is up to 1-2.
Embodiment 2
A kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea, is made up of the raw material of following weight portion: 5 parts of the Radix Rehmanniae, Caulis Akebiae 5 parts, Folium Bambusae 3
Part, poultry 5 parts, Folium Pyrrosiae 5 parts, Spora Lygodii 10 parts, Rhizoma Imperatae 5 parts, Herba Taraxaci 6 parts, Herba Houttuyniae 5 parts, Radix Astragali 5 parts, the Rhizoma Atractylodis Macrocephalae 5
Part, Cortex Mori 5 parts, Pericarpium Arecae 5 parts, Lignum Aquilariae Resinatum 5 parts, Stigma Maydis 5 parts, Pericarpium Citri Reticulatae 5 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts,
Mel, water are appropriate.Processing method is with embodiment 1.
Embodiment 3
A kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea, is made up of the raw material of following weight portion: 15 parts of the Radix Rehmanniae, Caulis Akebiae 12 parts, bamboo
9 parts of leaf, poultry 12 parts, Folium Pyrrosiae 10 parts, Spora Lygodii 16 parts, Rhizoma Imperatae 15 parts, Herba Taraxaci 15 parts, Herba Houttuyniae 10 parts, Radix Astragali 10
Part, the Rhizoma Atractylodis Macrocephalae 10 parts, Cortex Mori 10 parts, Pericarpium Arecae 10 parts, Lignum Aquilariae Resinatum 10 parts, Stigma Maydis 10 parts, Pericarpium Citri Reticulatae 10 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, fresh stone
Dry measure used in former times 20 parts, Fructus Vitis viniferae 20 parts, Mel, water are appropriate.Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding
Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days；In 7 days, mice is without death, OK
For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception,
Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not
See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that two kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100,
50g；Experimental mouse is randomly divided into two groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal
General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart,
The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach；
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no
Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach
Deng the most significant change, it is understood that through proved by pathology, two kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is
Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 30 days
3. number is drunk: 50 people
4. drinking method: 500mL for each person every day
5. index: after drinking, obvious damp invasion of lower energizer, the kidney bladder deficiency of YIN, dampness blocking in middle-JIAO, affection of exogenous wind-cold, fever with aversion to cold, urine are not
The transference cure such as profit, hematuria dysurea, tired mind, inappetence, and mouthfeel is the most sour-sweet for effective；Drink rear damp invasion of lower energizer, kidney
The symptoms such as the bladder deficiency of YIN, dampness blocking in middle-JIAO, affection of exogenous wind-cold, fever with aversion to cold, dysuria, hematuria dysurea, tired mind, inappetence
Alleviate, and mouthfeel is the most sour-sweet, be designated as effectively.It is invalid to be then designated as without obvious comfort after drinking.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried
The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially
Increase comfort.
The each embodiment of table 1 drinks effect research table
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Embodiment 1 | 44%(22) | 54%(27) | 2%(1) |
| Embodiment 2 | 42%(21) | 56%(28) | 2%(1) |
| Embodiment 3 | 42%(21) | 56%(28) | 2%(1) |
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling
Method；The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 4 | 36%(18) | 40%(20) | 24%(12) |
| Comparative example 5 | 40%(20) | 40%(20) | 20%(10) |
| Comparative example 6 | 46%(23) | 34%(17) | 20%(10) |
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1
The preparation processing method of step E；The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 7 | 32%(16) | 56%(28) | 12%(6) |
| Comparative example 8 | 28%(14) | 52%(31) | 10%(5) |
| Comparative example 9 | 36%(18) | 52%(26) | 12%(6) |
Embodiment contrast groups C
The processing method of comparative example 10,11,12 respectively corresponding embodiment 1,2,3 and formula, different be formula in
Without Air Bladder pseudosciaenae seu Acipenser composition；The investigation method of using method and using effect is with above.
Table 4 embodiment contrast groups C drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 10 | 44%(22) | 46%(23) | 10%(5) |
| Comparative example 11 | 38%(19) | 50%(25) | 12%(6) |
| Comparative example 12 | 40%(20) | 48%(24) | 12%(6) |
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3；This shows Chinese crude drug formula of the present invention
And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine
Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally
The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc.
Function, strengthens immune system ability；Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously
The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology
Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional
Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step
The preparation processing method of rapid E has had significant raising than traditional boiling method, the extraction degree of active ingredient.
Table 1 is compared with table 4:
The formula of embodiment contrast groups C does not contains Air Bladder pseudosciaenae seu Acipenser, and the invalid number of embodiment contrast groups C is 5 times of left sides of embodiment 1,2,3
Right；And effective percentage and obvious effective rate number have and have declined；Show Air Bladder pseudosciaenae seu Acipenser serve in formula collaborative and priming return through work
With, Air Bladder pseudosciaenae seu Acipenser application effect achieves unexpected technique effect.
In sum, a kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea that the present invention provides, clearing away heat and promoting diuresis hemostasis, profit of inducing sweat
Urinate, circulation of qi promoting disappears water treatment acute nephritis, has sour-sweet mouthfeel, improves body immunity, defying age, eliminating toxin and beautifying the skin, nourishing spleen
Stomach, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful.And all raw materials is all from, and medicine-food two-purpose is natural plants
Thing, has no side effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (7)
1. a clearing away heat and promoting diuresis treatment acute nephritis medicated tea, it is characterised in that be made up of the raw material of following weight portion: Radix Rehmanniae 5-15
Part, Caulis Akebiae 5-12 part, Folium Bambusae 3-9 part, poultry 5-12 part, Folium Pyrrosiae 5-10 part, Spora Lygodii 10-16 part, Rhizoma Imperatae 5-15 part, Pu Gong
English 6-15 part, Herba Houttuyniae 5-10 part, Radix Astragali 5-10 part, Rhizoma Atractylodis Macrocephalae 5-10 part, Cortex Mori 5-10 part, Pericarpium Arecae 5-10 part, Lignum Aquilariae Resinatum 5-
10 parts, Stigma Maydis 5-10 part, Pericarpium Citri Reticulatae 5-10 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel, water fit
Amount.
A kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea the most according to claim 1, it is characterised in that by following weight portion
Raw material make: 10 parts of the Radix Rehmanniae, Caulis Akebiae 10 parts, 8 parts of Folium Bambusae, poultry 10 parts, Folium Pyrrosiae 8 parts, Spora Lygodii 12 parts, Rhizoma Imperatae 12 parts,
Herba Taraxaci 12 parts, Herba Houttuyniae 8 parts, Radix Astragali 8 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, Cortex Mori 8 parts, Pericarpium Arecae 8 parts, Lignum Aquilariae Resinatum 8 parts, Stigma Maydis 8 parts, old
Skin 8 parts, 8 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water are appropriate.
A kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea the most according to claim 1, it is characterised in that by following weight portion
Raw material make: 5 parts of the Radix Rehmanniae, Caulis Akebiae 5 parts, 3 parts of Folium Bambusae, poultry 5 parts, Folium Pyrrosiae 5 parts, Spora Lygodii 10 parts, Rhizoma Imperatae 5 parts, Pu Gong
English 6 parts, Herba Houttuyniae 5 parts, Radix Astragali 5 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Cortex Mori 5 parts, Pericarpium Arecae 5 parts, Lignum Aquilariae Resinatum 5 parts, Stigma Maydis 5 parts, Pericarpium Citri Reticulatae 5
Part, 5 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Mel, water are appropriate.
A kind of clearing away heat and promoting diuresis treatment acute nephritis medicated tea the most according to claim 1, it is characterised in that by following weight portion
Raw material make: 15 parts of the Radix Rehmanniae, Caulis Akebiae 12 parts, 9 parts of Folium Bambusae, poultry 12 parts, Folium Pyrrosiae 10 parts, Spora Lygodii 16 parts, Rhizoma Imperatae 15 parts,
Herba Taraxaci 15 parts, Herba Houttuyniae 10 parts, Radix Astragali 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Cortex Mori 10 parts, Pericarpium Arecae 10 parts, Lignum Aquilariae Resinatum 10 parts, Stigma Maydis
10 parts, Pericarpium Citri Reticulatae 10 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Mel, water appropriate.
5. the preparation processing method of a clearing away heat and promoting diuresis treatment acute nephritis medicated tea, it is characterised in that comprise the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Cortex Mori, Pericarpium Arecae, Lignum Aquilariae Resinatum, Stigma Maydis, Pericarpium Citri Reticulatae cleaning and sterilizing, respectively with 6 times of weight 85% mole
Ratio ethanol extraction 2 times, each 2 hours, merges 2 Cortex Mori, Pericarpium Arecae, Lignum Aquilariae Resinatum, Stigma Maydis, Pericarpium Citri Reticulatae ethanol extracts, stands alcohol
Heavy, to filter, filtrate is concentrated into without alcohol taste, and to be evaporated to relative density at 40 DEG C be 1.15-1.35, prepared Cortex Mori, big abdomen
Skin, Lignum Aquilariae Resinatum, Stigma Maydis, Pericarpium Citri Reticulatae extract standby；
Rhizoma Imperatae, Herba Taraxaci, Herba Houttuyniae, Radix Astragali, the Rhizoma Atractylodis Macrocephalae being closed stirring and put into super micron mill, super micron mill heating keeps
Temperature 80 degree 5-6 minute, carries out micronizing and obtains the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro mixing fine powders
Quality 6～the distilled water of 8 times, first soak 10min～15min, pour in volatile oil extractor, the way of distillation extract volatile oil 2～
4h, it is thus achieved that volatile oil and ultra micro mixing fine powders medicinal residues；
Take the Radix Rehmanniae, Caulis Akebiae, Folium Bambusae, poultry, Folium Pyrrosiae, Spora Lygodii, Air Bladder pseudosciaenae seu Acipenser, after mix homogeneously adds 30-60 DEG C of warm water soaking 10 minutes,
Put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine block, by freezing medicine block and ultra micro mixing fine powders
Medicinal residues boiling is extracted 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out infusion 10-20 minute；The
Secondary adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times amount water, and temperature keeps
120-150 DEG C, carry out infusion 30 minutes, filter, be concentrated into the 1/2 of original volume, add Cortex Mori, Pericarpium Arecae, Lignum Aquilariae Resinatum, Semen Maydis
Palpus, the extract of Pericarpium Citri Reticulatae and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
The preparation processing method of a kind of clearing away heat and promoting diuresis the most according to claim 5 treatment acute nephritis medicated tea, its feature exists
In, step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute, make grapevine knot
Ice, after taking out nature defrosting, then carries out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
The preparation processing method of a kind of clearing away heat and promoting diuresis the most according to claim 5 treatment acute nephritis medicated tea, its feature exists
In, step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae be
10:0.2～0.8:5～10:0.5.
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| CN107281445A (en) * | 2017-06-27 | 2017-10-24 | 张可池 | A kind of Chinese herb compound for preventing and treating pet teacup dog ascites symptoms and preparation method thereof |
| CN107455512A (en) * | 2017-09-12 | 2017-12-12 | 乌鲁木齐市哈力馨蒙中医医院(股份有限公司） | A kind of dandelion wrinkled giant hyssop tea solid beverage（Anti-inflammatory tea for promotion of diuresis）And preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107281445A (en) * | 2017-06-27 | 2017-10-24 | 张可池 | A kind of Chinese herb compound for preventing and treating pet teacup dog ascites symptoms and preparation method thereof |
| CN107455512A (en) * | 2017-09-12 | 2017-12-12 | 乌鲁木齐市哈力馨蒙中医医院(股份有限公司） | A kind of dandelion wrinkled giant hyssop tea solid beverage（Anti-inflammatory tea for promotion of diuresis）And preparation method thereof |
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Application publication date: 20161207 |