CN106165745A - The medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia and preparation processing method - Google Patents
The medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia and preparation processing method Download PDFInfo
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- CN106165745A CN106165745A CN201610234287.3A CN201610234287A CN106165745A CN 106165745 A CN106165745 A CN 106165745A CN 201610234287 A CN201610234287 A CN 201610234287A CN 106165745 A CN106165745 A CN 106165745A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/34—Tea substitutes, e.g. matè; Extracts or infusions thereof
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- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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Abstract
The invention discloses the medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia of the present invention, be made up of the raw material of following weight portion: Fructus Lycii 1 10 parts, Flos Chrysanthemi 5 15 parts, 39 parts of Radix Rehmanniae Preparata, Rhizoma Dioscoreae 5 12 parts, 39 parts of Folium Pini, Radix Angelicae Sinensis 39 parts, the Radix Astragali 5 12 parts, Nodus Nelumbinis Rhizomatis 5 10 parts, Herba Agrimoniae 10 30 parts, Rhizoma Imperatae 5 10 parts, the Radix Polygoni Multiflori 10 16 parts, Semen Cuscutae 5 15 parts, Radix Codonopsis 6 15 parts, Carapax et Plastrum Testudinis 5 10 parts, Caulis Spatholobi 5 10 parts, Fructus Mori 5 10 parts, Radix Paeoniae Rubra 10 15 parts.The invention have the advantage that inventive formulation QI invigorating nourishing kidney-YIN can treat yin asthenia generating intrinsic heat, QI and blood pair is lost, QI failing to control blood causes thrombocytopenia, anorexia, middle gas not to save, and improves body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.
Description
Technical field
The present invention relates to the medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia, in particular, relate to one
The herb tea formula planting QI invigorating nourishing kidney-YIN treatment thrombocytopenia and preparation method thereof technical field.
Background technology
Thrombocytopenia is owing to platelet counts minimizing or hypofunction (Thromboasthenia) cause tampon
Formed bad and hemorrhage and cause.Platelet count less than normal range 140,000 ~ 400,000/μ l, thrombocytopenia, yin asthenia generating intrinsic heat,
QI and blood is double thanks to, QI failing to control blood may come from platelet and produce deficiency;Show as having palpitation, lumbago frequent micturition, shallow complexion, food stagnation not
Disappear, anorexia, the symptom such as middle gas not province;The traditional Chinese medical science is thought can pass through QI invigorating nourishing kidney-YIN, treats thrombocytopenia.
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, and does not have QI invigorating nourishing kidney-YIN, and treatment platelet subtracts
Few disease, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, drop three-hypers, prevent and treat diabetes and anti-cancer, the side such as anticancer
The function in face, it is impossible to releasing the sufferings of client, and traditional herbal tea is by Traditional medicine infusion, flavour of a drug weight mouthfeel is poor, it is impossible to protect for a long time
Deposit.The most not yet occur a kind of in good taste, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen body immunity simultaneously
Beverage.
Summary of the invention
The present invention is directed to the deficiency of existing product, and provide a kind of fresh juice beverage to regulate the effect of human physiological functions,
This beverage have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach,
Cure the disease the medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia simultaneously strengthening the advantages such as body immunity.
The medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia, is made up of the raw material of following weight portion: Fructus Lycii
1-10 part, Flos Chrysanthemi 5-15 part, Radix Rehmanniae Preparata 3-9 part, Rhizoma Dioscoreae 5-12 part, Folium Pini 3-9 part, Radix Angelicae Sinensis 3-9 part, Radix Astragali 5-12 part, Nodus Nelumbinis Rhizomatis 5-
10 parts, Herba Agrimoniae 10-30 part, Rhizoma Imperatae 5-10 part, Radix Polygoni Multiflori 10-16 part, Semen Cuscutae 5-15 part, Radix Codonopsis 6-15 part, Carapax et Plastrum Testudinis 5-10 part,
Caulis Spatholobi 5-10 part, Fructus Mori 5-10 part, Radix Paeoniae Rubra 10-15 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part,
Mel, water are appropriate.
The preparation processing method of the medicated tea of described a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia, including following step
Suddenly;
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby;
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20~30r/s;After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80~100r/s, stands 10min;
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100~
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber;The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by;
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby;
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby;After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II;
E, take mix homogeneously after Radix Angelicae Sinensis, Radix Codonopsis and Caulis Spatholobi cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2
Secondary, each 2 hours, merge 2 Radix Angelicae Sinensis, Radix Codonopsis and the ethanol extract of Caulis Spatholobi, receive alcohol and be also evaporated at 40 DEG C relatively
Density is 1.15-1.35, and the extract preparing Radix Angelicae Sinensis, Radix Codonopsis and Caulis Spatholobi is standby;
The Radix Polygoni Multiflori, the Radix Astragali, Carapax et Plastrum Testudinis, Radix Rehmanniae Preparata mix and blend are put into super micron mill, carry out micronizing obtain 300-400 purpose surpass
Microring array fine powder;
Take Fructus Lycii, Flos Chrysanthemi, Rhizoma Dioscoreae, Folium Pini, Nodus Nelumbinis Rhizomatis, Herba Agrimoniae, Rhizoma Imperatae, Semen Cuscutae, Fructus Mori, Radix Paeoniae Rubra, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously
After adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10~-20 DEG C freezing 10-20 minute, form freezing medicine
Block, extracts freezing medicine block and ultra micro mixing fine powders boiling 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120
DEG C, carry out infusion 10-20 minute;Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes;For the third time
Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, and is concentrated into the 1/2 of original volume, adds and works as
Return, Radix Codonopsis and the extract of Caulis Spatholobi, obtain Matrix Solution III standby;
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank;Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank;Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank;
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae;
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100~120 DEG C, 1.5MP, sterilization in 15~21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer ,-10~-20 DEG C freezing 5-10 minute,
Make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Further: step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion be 10:0.2~0.8:5~10:0.5.
Fructus Lycii, sweet, flat, for syndrome of yin deficiency of liver and kidney, sweet flat matter is moistened, flat invigorating the liver and kidney, has strengthening by means of tonics effect, and all Liver and kidney are cloudy
Empty all cards all can be applied.
Flos Chrysanthemi, bitter in the mouth, pungent, cool, heat-clearing and toxic substances removing, wind-dispelling heat-dissipating, dissipating blood stasis, improving eyesight, blood pressure lowering.
Radix Rehmanniae Preparata, sweet, tepor.Returning liver, kidney channel, yin nourishing of enriching blood, life essence-filling, marrow-benefitting, sweet Wen Zhirun, nourishing YIN benefit essence is with hemopoietic.
Rhizoma Dioscoreae is sweet, flat, nontoxic, returns spleen, lung, kidney channel, invigorating spleen and reinforcing stomach.Aid digestion;Average containing thick protein 14.48%, slightly fine
Dimension 3.48%, starch 43.7%, sugar 1.14%, potassium 2.62%, phosphorus 0.2%, calcium 0.2%, magnesium 0.14%, ash 5.51%, ferrum 53.57ppm,
Zinc 29.22ppm, copper 10.58ppm, manganese 5.38ppm.In 18 kinds of aminoacid of necessary for human, containing 16 kinds in Rhizoma Dioscoreae.
Folium Pini, bitter, puckery, temperature.Expelling wind and activating blood circulation, improving eyesight, calm the nerves, removing toxic substances, antipruritic.For influenza, rheumatic arthritis,
Treating swelling and pain by traumatic injury, nyctalopia, hypertension, neurasthenia;External treating chilblain.
Radix Angelicae Sinensis, sweet, pungent, warm, return liver, the heart, spleen channel, enrich blood;Invigorate blood circulation;Menstruction regulating and pain relieving;Moisturize laxation.
The Radix Astragali, returns lung, spleen, liver, kidney channel.Enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and
Wide antibacterial action.
Nodus Nelumbinis Rhizomatis, returns liver, lung, stomach warp, astringing to arrest bleeding, blood stasis dispelling.
Herba Agrimoniae is bitter, cool.Return stomach, liver, spleen, lung, large intestine channel.Relieve internal heat anticancer, cooling blood for hemostasis, detumescent of healing the wounds.
Rhizoma Imperatae, returns lung, stomach, bladder warp.Cooling blood for hemostasis, clearing away heat and promoting diuresis.
The Radix Polygoni Multiflori, tonification essence and blood, crow beard and hair, bone and muscle strengthening, invigorating the liver and kidney.
Semen Cuscutae, the kidney invigorating and essence nourishing;Nourishing the liver to improve visual acuity;Gu tire stopping leak.Main soreness of waist and knee joint;Seminal emission;Sexual impotence;Premature ejaculation;Sterile;Disappear
Yearningly;Stranguria with turbid discharge;The enuresis;Blurred vision tinnitus.
Radix Codonopsis, sweet, flat.Invigorating the spleen and replenishing QI, stomach function regulating promotes the production of body fluid, expelling phlegm for arresting cough, for weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength,
Lack of appetite, thirsty.
Carapax et Plastrum Testudinis, salty, sweet, flat, enter liver, kidney two warp.Primary efficacy is nourishing YIN for suppressing the hyperactive YANG, replenishing YIN and removing heat, Kidney-invigorating and tendon-reinforcing, only collapses treatment
Leakage, the kidney invigorating benefit heart, eliminating carbuncle control skin ulcer.
Caulis Spatholobi, relaxing muscles and tendons to promote blood circulation;Nourishing blood for regulating menstruation.Main numb hand and foot;Quadriplegia;Rheumatic arthralgia.
Fructus Mori, sweet in the mouth, cold in nature.Nourishing YIN and supplementing blood, promotes the production of body fluid, intestine moistening, for weakness due to chronic disease, hepatic and renal YIN deficiency, soreness of the waist and knees, mesh
Dark tinnitus, articular instability, dryness of the intestine constipation, body fluid deficiency insufficiency of blood, hectic fever seminal emission, diabetes etc..
Radix Paeoniae Rubra, bitter, it is slightly cold.Return Liver Channel.There is clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling.
Being share by the natural tradition medicinal and edible Chinese medicine above with multiple health care, QI invigorating nourishing kidney-YIN can treat blood
Platelet reduces disease, improves body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.Sieved by great many of experiments
Select the proportioning of each component, scientific and reasonable;And whole preparation technology is rationally and extract drugs rate efficiency is high, can retain former well
Effective ingredient in material, does not bring any impurity, and sweet mouthfeel into, has no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines
Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported
Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax
Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect;Immune system ability can be strengthened, there is strong anti-oxidation, resist
Suddenly change, alleviate the function such as hepatosis, protection cardiovascular;
3, add the Chinese herbal medicine such as Fructus Lycii, Flos Chrysanthemi, Rhizoma Dioscoreae, Folium Pini, Nodus Nelumbinis Rhizomatis, Herba Agrimoniae, Rhizoma Imperatae, Semen Cuscutae, Fructus Mori and there is benefit
The merit such as gas nourishing kidney-YIN treatment thrombocytopenia, raising body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, resisting fatigue
Energy.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has
The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and
Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1-
2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
The medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia, is made up of the raw material of following weight portion: Fructus Lycii 5 parts,
Flos Chrysanthemi 10 parts, 8 parts of Radix Rehmanniae Preparata, Rhizoma Dioscoreae 10 parts, 8 parts of Folium Pini, Radix Angelicae Sinensis 8 parts, the Radix Astragali 7 parts, Nodus Nelumbinis Rhizomatis 7 parts, Herba Agrimoniae 15 parts, Rhizoma Imperatae 8 parts,
The Radix Polygoni Multiflori 12 parts, Semen Cuscutae 12 parts, Radix Codonopsis 12 parts, Carapax et Plastrum Testudinis 8 parts, Caulis Spatholobi 8 parts, Fructus Mori 8 parts, Radix Paeoniae Rubra 12 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, new
Fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water are appropriate.
The preparation processing method of the medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia, described preparation method includes
Following steps;
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby;
Fresh for the Herba Dendrobii cleaned up bar is put into microwave oven by B, keeps temperature 50-60 DEG C, carries out heating 10 minutes, further take out
Put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content 52 of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
DEG C Chinese liquor, time 15min, the rotating speed of juice extractor is 30r/s;After standing 10 minutes, add the steaming of Herba Dendrobii fresh bar weight 2.5 times
Distilled water, for the second time juice extractor time 15min, juice extractor rotating speed is 80r/s, stands 10min;After carry out third time squeeze the juice, add
The distilled water of Herba Dendrobii fresh bar weight 3-5 times, time 30min, juice extractor rotating speed is 150r/s, by fresh for Herba Dendrobii bar juice and fiber mistake
Filter separate, make the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, broken cell rate reaches more than 80%, obtain new fresh Herba Dendrobii juice and
Herba Dendrobii fresh bar fiber;Again new fresh grape is put into after the warm water of 55 DEG C cleans up, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated
Stand-by;After new fresh grape cleans up, put into reach in freezer ,-10 ~-20 DEG C of freezings 10 minutes, make Fructus Vitis viniferae freeze, take out certainly
After so thawing, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 120 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby;
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 6 times of weight, stirring is smashed to 100 mesh, 30-35 DEG C of temperature
Degree lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby;Extract the Fructus Vitis viniferae after Matrix Solution
It is the cellulase of 0.5-0.7% that skin and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, keeps
35 DEG C, water soluble dietary fiber can be extracted after 24h enzymolysis further, water soluble dietary fiber is added Matrix Solution and obtains
Matrix Solution II;;Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to protection human body is from the damage of free radical, it is possible to enhancing blood vessel elasticity,
Lax blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect;Immune system ability can be strengthened, there is strong antioxygen
Change, mutation, alleviate hepatosis, protection function, Pericarpium Vitis viniferae and the Herba Dendrobii fresh bar fiber such as cardiovascular together with stir smash through
Anthocyanidin mentioned by hydromel, can protect the quality of anthocyanidin while farthest extracting anthocyanidin.By water solublity meals
Food fiber adds Matrix Solution and obtains Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged
External;Adsorb various metabolic waste, be allowed to normally excrete, improve the comprehensive utilization value of Herba Dendrobii.
E, take mix homogeneously after Radix Angelicae Sinensis, Radix Codonopsis and Caulis Spatholobi cleaning and sterilizing, carry with 6 times of weight 85% mol ratio ethanol respectively
Take 2 times, each 2 hours, merge 2 Radix Angelicae Sinensis, Radix Codonopsis and the ethanol extract of Caulis Spatholobi, receive alcohol and be also evaporated to phase at 40 DEG C
Being 1.15-1.35 to density, the extract preparing Radix Angelicae Sinensis, Radix Codonopsis and Caulis Spatholobi is standby;
The Radix Polygoni Multiflori, the Radix Astragali, Carapax et Plastrum Testudinis, Radix Rehmanniae Preparata mix and blend are put into super micron mill, carry out micronizing obtain 300-400 purpose surpass
Microring array fine powder;
Take Fructus Lycii, Flos Chrysanthemi, Rhizoma Dioscoreae, Folium Pini, Nodus Nelumbinis Rhizomatis, Herba Agrimoniae, Rhizoma Imperatae, Semen Cuscutae, Fructus Mori, Radix Paeoniae Rubra, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously
After adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10~-20 DEG C freezing 10-20 minute, form freezing medicine
Block, extracts freezing medicine block and ultra micro mixing fine powders boiling 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120
DEG C, carry out infusion 10-20 minute;Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes;For the third time
Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, and is concentrated into the 1/2 of original volume, adds and works as
Return, Radix Codonopsis and the extract of Caulis Spatholobi, obtain Matrix Solution III standby;
The hard to bear medicine boiled is pulverized and improves its extract drugs efficiency, make whole formula drug effect farthest be utilized.
F, take Matrix Solution I through instantaneous high-temperature 120 DEG C, 1-2 minute, put into material-compound tank;Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank;Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank;
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae;Supercritical extraction can be
Extract under room temperature 37 DEG C and CO2 gas blanket, effectively prevent oxidation and the loss of heat-sensitive substance.Therefore,
The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the easy material being pyrolyzed the lowest
Extract under its boiling temperature;
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, and described material-compound tank endobasal-body solution I, matrix are molten
Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5., seal through bottle capper and load vial
In, packaged vial puts into temperature 100~120 DEG C, 1.5MP, sterilization in 15~21 minutes steam ovens, packaging, dress
Case, carries and drinks conveniently, and the shelf-life is up to 1-2.
Embodiment 2
The medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia, is made up of the raw material of following weight portion: Fructus Lycii 1 part,
Flos Chrysanthemi 5 parts, 3 parts of Radix Rehmanniae Preparata, Rhizoma Dioscoreae 5 parts, 3 parts of Folium Pini, Radix Angelicae Sinensis 3 parts, the Radix Astragali 5 parts, Nodus Nelumbinis Rhizomatis 5 parts, Herba Agrimoniae 10 parts, Rhizoma Imperatae 5 parts, head
Crow 10 parts, Semen Cuscutae 5 parts, Radix Codonopsis 6 parts, Carapax et Plastrum Testudinis 5 parts, Caulis Spatholobi 5 parts, Fructus Mori 5 parts, Radix Paeoniae Rubra 10 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, fresh stone
Dry measure used in former times 10 parts, Fructus Vitis viniferae 10 parts, Mel, water are appropriate.Processing method is with embodiment 1.
Embodiment 3
The medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia, is made up of the raw material of following weight portion: Fructus Lycii 10 parts,
Flos Chrysanthemi 15 parts, 9 parts of Radix Rehmanniae Preparata, Rhizoma Dioscoreae 12 parts, 9 parts of Folium Pini, Radix Angelicae Sinensis 9 parts, the Radix Astragali 12 parts, Nodus Nelumbinis Rhizomatis 10 parts, Herba Agrimoniae 30 parts, Rhizoma Imperatae 10
Part, the Radix Polygoni Multiflori 16 parts, Semen Cuscutae 15 parts, Radix Codonopsis 15 parts, Carapax et Plastrum Testudinis 10 parts, Caulis Spatholobi 10 parts, Fructus Mori 10 parts, Radix Paeoniae Rubra 15 parts, Air Bladder pseudosciaenae seu Acipenser
10 parts, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Mel, water appropriate.Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding
Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days;In 7 days, mice is without death, OK
For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception,
Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not
See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that three kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100,
50g;Experimental mouse is randomly divided into three groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal
General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart,
The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach;
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no
Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach
Deng the most significant change, it is understood that through proved by pathology, three kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is
Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 30 days
3. number is drunk: 50 people
4. drinking method: 3 times for each person every day, ante cibum each 500mL
5. index: after drinking, substantially sensation easily fatigue, thrombocytopenia, yin asthenia generating intrinsic heat, QI and blood be double thanks to, QI failing to control blood, the heart
Unbearably, lumbago frequent micturition, shallow complexion, food stagnation do not disappear, anorexia, the transference cure such as middle gas not province, and mouthfeel is the most sour-sweet for effective;
Sensation easily fatigue after drinking, thrombocytopenia, yin asthenia generating intrinsic heat, QI and blood be double loses, QI failing to control blood, have palpitation, lumbago frequent micturition, complexion are withered
Yellow, food stagnation does not disappears, anorexia, middle gas do not save remission, and mouthfeel is the most sour-sweet, is designated as effectively.Without the most comfortable after drinking
It is invalid that sense is then designated as.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried
The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially
Increase comfort.
The each embodiment of table 1 drinks effect research table
Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
Embodiment 1 | 44%(22) | 54%(27) | 2%(1) |
Embodiment 2 | 42%(21) | 56%(28) | 2%(1) |
Embodiment 3 | 42%(21) | 56%(28) | 2%(1) |
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling
Method;The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
Comparative example 4 | 36%(18) | 40%(20) | 24%(12) |
Comparative example 5 | 40%(20) | 40%(20) | 20%(10) |
Comparative example 6 | 46%(23) | 34%(17) | 20%(10) |
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1
The preparation processing method of step E;The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
Comparative example 7 | 32%(16) | 56%(28) | 12%(6) |
Comparative example 8 | 28%(14) | 52%(31) | 10%(5) |
Comparative example 9 | 36%(18) | 52%(26) | 12%(6) |
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3;This shows Chinese crude drug formula of the present invention
And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine
Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally
The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc.
Function, strengthens immune system ability;Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously
The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology
Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional
Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step
The preparation processing method of rapid E has had huge raising than traditional boiling method, the extraction degree of active ingredient.
In sum, the medicated tea of a kind of QI invigorating nourishing kidney-YIN treatment thrombocytopenia that the present invention provides has sour-sweet
Mouthfeel, has the most again that treatment easily fatigue, thrombocytopenia, yin asthenia generating intrinsic heat, QI and blood double are lost, QI failing to control blood, nervous, lumbago are urinated simultaneously
Frequently, shallow complexion, food stagnation do not disappear, anorexia, middle gas do not save merit, improve body immunity, defying age, eliminating toxin and beautifying the skin, taste
Support taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful.And all raw materials is all from medicine-food two-purpose sky
So plant, has no side effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (7)
1. the medicated tea of a QI invigorating nourishing kidney-YIN treatment thrombocytopenia, it is characterised in that by the raw material system of following weight portion
Become: Fructus Lycii 1-10 part, Flos Chrysanthemi 5-15 part, Radix Rehmanniae Preparata 3-9 part, Rhizoma Dioscoreae 5-12 part, Folium Pini 3-9 part, Radix Angelicae Sinensis 3-9 part, Radix Astragali 5-12
Part, Nodus Nelumbinis Rhizomatis 5-10 part, Herba Agrimoniae 10-30 part, Rhizoma Imperatae 5-10 part, Radix Polygoni Multiflori 10-16 part, Semen Cuscutae 5-15 part, Radix Codonopsis 6-15 part, Testudinis
Plate 5-10 part, Caulis Spatholobi 5-10 part, Fructus Mori 5-10 part, Radix Paeoniae Rubra 10-15 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, new fresh Herba Dendrobii 10-20 part, Portugal
Grape 10-20 part, Mel, water are appropriate.
The medicated tea of a kind of QI invigorating nourishing kidney-YIN the most according to claim 1 treatment thrombocytopenia, it is characterised in that by
The raw material of following weight portion is made: Fructus Lycii 5 parts, Flos Chrysanthemi 10 parts, 8 parts of Radix Rehmanniae Preparata, Rhizoma Dioscoreae 10 parts, 8 parts of Folium Pini, Radix Angelicae Sinensis 8 parts, the Radix Astragali
7 parts, Nodus Nelumbinis Rhizomatis 7 parts, Herba Agrimoniae 15 parts, Rhizoma Imperatae 8 parts, the Radix Polygoni Multiflori 12 parts, Semen Cuscutae 12 parts, Radix Codonopsis 12 parts, Carapax et Plastrum Testudinis 8 parts, Caulis Spatholobi 8
Part, Fructus Mori 8 parts, Radix Paeoniae Rubra 12 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water are appropriate.
The medicated tea of a kind of QI invigorating nourishing kidney-YIN the most according to claim 1 treatment thrombocytopenia, it is characterised in that by
The raw material of following weight portion is made: Fructus Lycii 1 part, Flos Chrysanthemi 5 parts, 3 parts of Radix Rehmanniae Preparata, Rhizoma Dioscoreae 5 parts, 3 parts of Folium Pini, Radix Angelicae Sinensis 3 parts, the Radix Astragali 5
Part, Nodus Nelumbinis Rhizomatis 5 parts, Herba Agrimoniae 10 parts, Rhizoma Imperatae 5 parts, the Radix Polygoni Multiflori 10 parts, Semen Cuscutae 5 parts, Radix Codonopsis 6 parts, Carapax et Plastrum Testudinis 5 parts, Caulis Spatholobi 5 parts, Mulberry
Shen 5 parts, Radix Paeoniae Rubra 10 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Mel, water are appropriate.
The medicated tea of a kind of QI invigorating nourishing kidney-YIN the most according to claim 1 treatment thrombocytopenia, it is characterised in that by
The raw material of following weight portion is made: Fructus Lycii 10 parts, Flos Chrysanthemi 15 parts, 9 parts of Radix Rehmanniae Preparata, Rhizoma Dioscoreae 12 parts, 9 parts of Folium Pini, Radix Angelicae Sinensis 9 parts, Huang
Stilbene 12 parts, Nodus Nelumbinis Rhizomatis 10 parts, Herba Agrimoniae 30 parts, Rhizoma Imperatae 10 parts, the Radix Polygoni Multiflori 16 parts, Semen Cuscutae 15 parts, Radix Codonopsis 15 parts, Carapax et Plastrum Testudinis 10 parts, chicken
Caulis seu Radix Schisandrae Henryi 10 parts, Fructus Mori 10 parts, Radix Paeoniae Rubra 15 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Mel, water are appropriate.
5. the preparation processing method of the medicated tea of QI invigorating nourishing kidney-YIN treatment thrombocytopenia, it is characterised in that include with
Lower step;
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby;
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20~30r/s;After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80~100r/s, stands 10min;
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100~
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber;The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by;
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby;
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby;After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II;
E, take mix homogeneously after Radix Angelicae Sinensis, Radix Codonopsis and Caulis Spatholobi cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2
Secondary, each 2 hours, merge 2 Radix Angelicae Sinensis, Radix Codonopsis and the ethanol extract of Caulis Spatholobi, receive alcohol and be also evaporated at 40 DEG C relatively
Density is 1.15-1.35, and the extract preparing Radix Angelicae Sinensis, Radix Codonopsis and Caulis Spatholobi is standby;
The Radix Polygoni Multiflori, the Radix Astragali, Carapax et Plastrum Testudinis, Radix Rehmanniae Preparata mix and blend are put into super micron mill, carry out micronizing obtain 300-400 purpose surpass
Microring array fine powder;
Take Fructus Lycii, Flos Chrysanthemi, Rhizoma Dioscoreae, Folium Pini, Nodus Nelumbinis Rhizomatis, Herba Agrimoniae, Rhizoma Imperatae, Semen Cuscutae, Fructus Mori, Radix Paeoniae Rubra, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously
After adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10~-20 DEG C freezing 10-20 minute, form freezing medicine
Block, extracts freezing medicine block and ultra micro mixing fine powders boiling 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120
DEG C, carry out infusion 10-20 minute;Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes;For the third time
Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, and is concentrated into the 1/2 of original volume, adds and works as
Return, Radix Codonopsis and the extract of Caulis Spatholobi, obtain Matrix Solution III standby;
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank;Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank;Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank;
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae;
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100~120 DEG C, 1.5MP, sterilization in 15~21 minutes steam ovens, packaging, vanning.
The preparation processing side of the medicated tea of a kind of QI invigorating nourishing kidney-YIN the most according to claim 5 treatment thrombocytopenia
Method, it is characterised in that step B) in, after new fresh grape cleans up, put into reach in freezer ,-10~-20 DEG C, freezing 5-10 divides
Clock, makes Fructus Vitis viniferae freeze, and after taking out nature defrosting, then carries out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
The preparation processing side of the medicated tea of a kind of QI invigorating nourishing kidney-YIN the most according to claim 5 treatment thrombocytopenia
Method, it is characterised in that step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion is 10:0.2~0.8:5~10:0.5.
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