CN106165807A - A kind of replenishing YIN and removing heat the kidney invigorating beverage and preparation processing method - Google Patents
A kind of replenishing YIN and removing heat the kidney invigorating beverage and preparation processing method Download PDFInfo
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- CN106165807A CN106165807A CN201610234318.5A CN201610234318A CN106165807A CN 106165807 A CN106165807 A CN 106165807A CN 201610234318 A CN201610234318 A CN 201610234318A CN 106165807 A CN106165807 A CN 106165807A
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- parts
- herba dendrobii
- fresh
- vitis viniferae
- radix
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Classifications
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention discloses a kind of replenishing YIN and removing heat the kidney invigorating beverage, be made up of the raw material of following weight portion: new fresh Herba Dendrobii 40 50, Fructus Vitis viniferae 25 35, Radix Codonopsis 3 10 parts, 3 60 parts of Gypsum Fibrosum, 3 10 parts of Poria, Rhizoma Coptidis 29 parts, Radix Scutellariae 35 parts, the Rhizoma Anemarrhenae 35 parts, Radix Trichosanthis 5 10 parts, the Cortex Eucommiae 2 10 parts, Fructus Lycii 2 10 parts, Carapax et Plastrum Testudinis 10 30 parts, Semen Cuscutae 10 20 parts, Folium Eupatorii 1 10 parts, Radix Ginseng 1 10 parts, Mel, water are appropriate.The invention have the advantage that inventive formulation has yin nourishing, heat clearing away, the kidney invigorating etc. function, regulation human physiological functions, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, there is the highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and carry and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously.
Description
Technical field
The present invention relates to a kind of replenishing YIN and removing heat the kidney invigorating beverage, in particular, relate to a kind of replenishing YIN and removing heat the kidney invigorating beverage
Formula and preparation method thereof technical field.
Background technology
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, it is impossible to treatment hyperactivity of fire caused by deficiency of YIN, does not have yin nourishing, clear
Heat, the kidney invigorating preventing and treating high fever coma, xerostomia crimson tongue, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency coughs, and interior-heat such as is quenched one's thirst at the symptom, it is impossible to
Releasing the sufferings of client, and traditional herbal tea is by Traditional medicine infusion, flavour of a drug weight mouthfeel is poor, it is impossible to preserve for a long time.In the market
Not yet occur a kind of in good taste, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously.
Summary of the invention
The present invention is directed to the deficiency of existing product, overcome existing traditional herbal tea by Traditional medicine infusion, flavour of a drug weight mouthfeel is poor,
The limitation that cannot preserve for a long time, and provide a kind of and make it as fresh juice beverage to regulate the effect of human physiological functions, this drink
Material have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach, cure the disease
Strengthen a kind of replenishing YIN and removing heat the kidney invigorating beverage of the advantages such as body immunity simultaneously.
A kind of replenishing YIN and removing heat the kidney invigorating beverage of the present invention, is made up of the raw material of following weight portion: new fresh Herba Dendrobii 40-50, Portugal
Grape 25-35, Radix Codonopsis 3-10 part, Gypsum Fibrosum 3-60 part, Poria 3-10 part, Rhizoma Coptidis 2-9 part, Radix Scutellariae 3-5 part, Rhizoma Anemarrhenae 3-5 part, Radix Trichosanthis
5-10 part, Cortex Eucommiae 2-10 part, Fructus Lycii 2-10 part, Carapax et Plastrum Testudinis 10-30 part, Semen Cuscutae 10-20 part, Folium Eupatorii 1-10 part, Radix Ginseng 1-10
Part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, Mel, water are appropriate.
The preparation processing method of a kind of replenishing YIN and removing heat the kidney invigorating beverage, described preparation method comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add Herba Dendrobii for the first time fresh
The Chinese liquor of alcohol content 52-60 DEG C of bar weight 0.1-0.5 times, time 10-15min, the rotating speed of juice extractor is 20～30r/s；
After standing 10 minutes, adding the distilled water of Herba Dendrobii fresh bar weight 2-3 times, juice extractor time 10-15min for the second time, juice extractor turns
Speed is 80～100r/s, stands 10min；After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, the time
20-30min, juice extractor rotating speed is 100～150r/s, is separated with fiber filter by fresh for Herba Dendrobii bar juice, makes the fibre of the fresh bar of Herba Dendrobii
Dimension separation rate reaches more than 95%, and broken cell rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；Again by fresh
Fructus Vitis viniferae is put into after the warm water of 50-60 DEG C cleans up, and obtains Fructus Vitis viniferae meat and Pericarpium Vitis viniferae；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
F, take Radix Codonopsis, Gypsum Fibrosum, Poria, Rhizoma Coptidis, Radix Scutellariae, the Rhizoma Anemarrhenae, Radix Trichosanthis, the Cortex Eucommiae, Fructus Lycii, Carapax et Plastrum Testudinis, Semen Cuscutae, Folium Eupatorii, people
After ginseng, Air Bladder pseudosciaenae seu Acipenser mix homogeneously add 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer, divide at-10 ~-20 DEG C of freezing 10-20
Clock, forms freezing medicine block, freezing medicine block boiling is extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120
DEG C, carry out infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；For the third time
Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, obtains matrix
Solution III is standby；
G, take Matrix Solution I through instantaneous high-temperature 150-160 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；Described material-compound tank endobasal-body solution I, Matrix Solution II, the weight proportion of Matrix Solution III are 3:1:2；
H, three kinds of Matrix Solutions, after material-compound tank stirs, seal through bottle capper and load in vial, packaged glass
Bottle puts into temperature 150 ~ 200 DEG C, 1.5MP, sterilization in 15 ~ 21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer, divide at-10 ~-20 DEG C of freezing 5-10
Clock, makes Fructus Vitis viniferae freeze, and after taking out nature defrosting, then carries out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Radix Scutellariae, has heat clearing and damp drying, removing heat from blood, detoxicating functions.
Poria, sweet in the mouth, light, property is put down, GUIXIN, lung, spleen, kidney channel, promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.
Radix Ginseng, sweet in the mouth, micro-hardship, warm in nature, flat.Return spleen, lung meridian, heart channel.QI invigorating, Gu de-, promote the production of body fluid, calm the nerves, Fructus Alpiniae Oxyphyllae.For gas
Short dyspnea with rapid and short breath, palpitation and amnesia, thirsty hyperhidrosis, lack of appetite is unable, all acute and chronic diseases and the shock caused after losing blood, collapse.Big benefit
Vigour, promotes the production of body fluid Gu de-, calms the nerves.
Radix Codonopsis, invigorating the spleen and replenishing QI, strengthening spleen and tonifying lung.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat disappears
Yearningly.
Gypsum Fibrosum, clearing away heat-fire, relieving restlessness is quenched the thirst, and restrains granulation promoting.
Rhizoma Coptidis is bitter；Cold, heart channel；Liver Channel；Stomach warp；Large intestine channel, pathogenic fire purging, dampness, removing toxic substances, parasite killing.Row pyretic toxicity when controlling, typhoid fever,
Intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, and lung knot is pressed, and tells, is defeated in battle, hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, pharynx
Larynx swells and ache, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.
The Rhizoma Anemarrhenae, returns lung, stomach, kidney channel.Clearing away heat-fire is nourshing Yin and drynsessmoistening prescription.Calentura excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat disappears
Yearningly, dryness of the intestine constipation.
Radix Trichosanthis, clearing away heat-fire, promoting the production of body fluid to quench thirst, evacuation of pus is subsided a swelling.
The Cortex Eucommiae, invigorating the liver and kidney, bone and muscle strengthening
Fructus Lycii, sweet, flat, for syndrome of yin deficiency of liver and kidney, sweet flat matter is moistened, and flat invigorating the liver and kidney has strengthening by means of tonics effect, and all hepatic and renal YIN deficiency are all
Card all can be applied.
Carapax et Plastrum Testudinis, salty, sweet, flat, enter liver, kidney two warp.Primary efficacy is nourishing YIN for suppressing the hyperactive YANG, replenishing YIN and removing heat, Kidney-invigorating and tendon-reinforcing, only collapses treatment
Leakage, the kidney invigorating benefit heart, eliminating carbuncle control skin ulcer.
Semen Cuscutae, the kidney invigorating and essence nourishing;Nourishing the liver to improve visual acuity;Gu tire stopping leak.Main soreness of waist and knee joint;Seminal emission;Sexual impotence;Premature ejaculation;Sterile;Disappear
Yearningly;Stranguria with turbid discharge;The enuresis;Blurred vision tinnitus.
Folium Eupatorii, appetizing of being amusing, deliver expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass vomiting and nausea, sweet greasy in mouth, halitosis, sialism, summer-heat
Wet table disease, feeling of fullness in the head is uncomfortable in chest.
By have above multiple health care natural tradition medicinal and edible Chinese medicine share, have yin nourishing, heat clearing away, the kidney invigorating it
Effect, has high fever coma, xerostomia crimson tongue, cardiopalmus of breathing hard, anorexia and loose stool, and dyspnea due to deficiency cough, interior-heat is quenched one's thirst；Food stagnation does not disappears, it
Merit.The proportioning of each component is screened by great many of experiments, scientific and reasonable；And whole preparation technology is reasonable and extract drugs rate efficiency
Height, can retain the effective ingredient in raw material well, does not bring any impurity, and sweet mouthfeel into, has no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines
Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported
Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax
Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong anti-oxidation, resist
Suddenly change, alleviate the function such as hepatosis, protection cardiovascular；
3, add Radix Codonopsis, Gypsum Fibrosum, Poria, Rhizoma Coptidis, Radix Scutellariae, the Rhizoma Anemarrhenae, Radix Trichosanthis, the Cortex Eucommiae, Fructus Lycii, Carapax et Plastrum Testudinis, Semen Cuscutae, Folium Eupatorii,
The Chinese herbal treatment hyperactivity of fire caused by deficiency of YIN such as Radix Ginseng have the functions such as yin nourishing, heat clearing away, the kidney invigorating.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has
The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and
Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1-
2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
A kind of replenishing YIN and removing heat the kidney invigorating beverage, it is characterised in that be made up of the raw material of following weight portion: new fresh Herba Dendrobii 38, Fructus Vitis viniferae 30,
Radix Codonopsis 4 parts, 30 parts of Gypsum Fibrosum, 5 parts of Poria, Rhizoma Coptidis 5 parts, Radix Scutellariae 5 parts, the Rhizoma Anemarrhenae 4 parts, Radix Trichosanthis 6 parts, the Cortex Eucommiae 5 parts, Fructus Lycii 5 parts, Testudinis
Plate 15 parts, Semen Cuscutae 15 parts, Folium Eupatorii 15 parts, Radix Ginseng 15 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water are appropriate.
The preparation processing method of a kind of replenishing YIN and removing heat the kidney invigorating beverage, described preparation method comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add Herba Dendrobii for the first time fresh
The Chinese liquor of the alcohol content that bar weight is 0.5 times 52 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；Stand 10 points
Zhong Hou, add Herba Dendrobii fresh bar weight 2.5 times distilled water, juice extractor time 15min for the second time, juice extractor rotating speed be 80～
100r/s, stands 10min；After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 5 times distilled water, time 20-30min, squeeze
Juice machine rotating speed is 100～150r/s, is separated with fiber filter by fresh for Herba Dendrobii bar juice, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach
More than 95%, broken cell rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；Again new fresh grape is put into
After the warm water of 50-60 DEG C cleans up, obtain Fructus Vitis viniferae meat and Pericarpium Vitis viniferae；After new fresh grape cleans up, put into reach in freezer,
Freezing 5-10 minute at-10 ~-20 DEG C, make Fructus Vitis viniferae freeze, take out after nature thaws, then carry out Fructus Vitis viniferae meat and separate work with Pericarpium Vitis viniferae
Industry.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 130 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 2 times of weight, stirring is smashed to 100 mesh, 35 DEG C of temperature
Lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby；Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to
Protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, lax blood vessel, increases systemic blood circulation, has certain
Blood pressure reduction effect；Immune system ability can be strengthened, there is strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular
Mention anthocyanidin etc. stirring to smash together with function, Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber through hydromel, can farthest extract
The quality of anthocyanidin can be protected while anthocyanidin.Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber addition mass volume ratio after extraction are
The cellulase of 0.5-0.7%, adds the water of the mass ratio of 1:10, keeps 35 DEG C, can extract water after 24h enzymolysis further
Soluble dietary fiber, adds water soluble dietary fiber Matrix Solution and obtains Matrix Solution II, can increase the merit of the wriggling of the intestines and stomach
Effect, it is ensured that metabolic waste normally excretes；Adsorb various metabolic waste, be allowed to normally excrete, improve the comprehensive of Herba Dendrobii
Value.
F, take Radix Codonopsis, Gypsum Fibrosum, Poria, Rhizoma Coptidis, Radix Scutellariae, the Rhizoma Anemarrhenae, Radix Trichosanthis, the Cortex Eucommiae, Fructus Lycii, Carapax et Plastrum Testudinis, Semen Cuscutae, Herba Eupatorii
After leaf, Radix Ginseng, Air Bladder pseudosciaenae seu Acipenser mix homogeneously add 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer, at-10 ~-20 DEG C of freezing 10-
20 minutes, forming freezing medicine block, freezing medicine block boiling extracted 3 times, add 1-2 times amount water for the first time, temperature keeps 100-
120 DEG C, carry out infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；The
Adding 6-10 times amount water for three times, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume,
Matrix Solution III is standby；
G, take Matrix Solution I through instantaneous high-temperature 150-160 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；Described material-compound tank endobasal-body solution I, Matrix Solution II, the weight proportion of Matrix Solution III are 3:1:2；This is joined
Sour-sweet more tasty and more refreshing than sense, desalinate Chinese medicine bitterness, and rich in dendrobium polysaccharide, there is the highest health care and medical value, drink for a long time
With can be moderate with YIN nourishing skin care, mouthfeel.
H, three kinds of Matrix Solutions, after material-compound tank stirs, seal through bottle capper and load in vial, packaged
Vial puts into temperature 150 ~ 200 DEG C, 1.5MP, sterilization in 15 ~ 21 minutes steam ovens, packaging, vanning, carries the side of drinking
Just, the shelf-life is up to 1-2.
Embodiment 2
A kind of replenishing YIN and removing heat the kidney invigorating beverage, is made up of the raw material of following weight portion: new fresh Herba Dendrobii 40, Fructus Vitis viniferae 25,3 parts of the Radix Rehmanniae, Huaihe River
Rhizoma Dioscoreae 3 parts, Radix Trichosanthis 2 parts, Rhizoma Alismatis 2 parts, Radix Ophiopogonis 2 parts, the Rhizoma Anemarrhenae 3 parts, the Radix Astragali 5 parts, Radix Puerariae 2 parts, Radix Polygoni Multiflori 2 parts, Retinervus Luffae Fructus 1
Part, 5 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water are appropriate.Processing method is with embodiment 1.
Embodiment 3
A kind of replenishing YIN and removing heat the kidney invigorating beverage, is made up of the raw material of following weight portion: new fresh Herba Dendrobii 50, Fructus Vitis viniferae 35,8 parts of the Radix Rehmanniae, Huaihe River
Rhizoma Dioscoreae 6 parts, Radix Trichosanthis 5 parts, Rhizoma Alismatis 5 parts, Radix Ophiopogonis 5 parts, the Rhizoma Anemarrhenae 5 parts, the Radix Astragali 10 parts, Radix Puerariae 10 parts, Radix Polygoni Multiflori 10 parts, Retinervus Luffae Fructus
2,10 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water are appropriate.Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding
Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days；In 7 days, mice is without death, OK
For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception,
Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not
See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that three kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100,
50g；Experimental mouse is randomly divided into three groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal
General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart,
The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach；
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no
Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach
Deng the most significant change, it is understood that through proved by pathology, three kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is
Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 20 days
3. number is drunk: 50 people
4. drinking method: 3 times for each person every day, each 300mL
5. index: substantially feel high fever coma, xerostomia crimson tongue, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat after drinking
Quench one's thirst；Food stagnation does not disappears, anorexia, middle gas do not save, fatigue symptom disappears, and mouthfeel is the most sour-sweet for effective；After drinking, sensation is strong
Hot coma, xerostomia crimson tongue；Food stagnation does not disappears, anorexia, middle gas do not save, fatigue symptom is alleviated, and mouthfeel is the most sour-sweet, has been designated as
Effect.It is invalid to be then designated as without obvious comfort after drinking.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried
The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially
Increase comfort.
The each embodiment of table 1 drinks effect research table
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Embodiment 1 | 44%(22) | 54%(27) | 2%(1) |
| Embodiment 2 | 42%(21) | 56%(28) | 2%(1) |
| Embodiment 3 | 42%(21) | 56%(28) | 2%(1) |
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling
Method；The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 4 | 36%(18) | 40%(20) | 24%(12) |
| Comparative example 5 | 40%(20) | 40%(20) | 20%(10) |
| Comparative example 6 | 46%(23) | 34%(17) | 20%(10) |
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1
The preparation processing method of step F；The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 7 | 32%(16) | 56%(28) | 12%(6) |
| Comparative example 8 | 28%(14) | 52%(31) | 10%(5) |
| Comparative example 9 | 36%(18) | 52%(26) | 12%(6) |
Embodiment contrast groups C
The processing method of comparative example 10,11,12 respectively corresponding embodiment 1,2,3 and formula, different be formula in
Without Air Bladder pseudosciaenae seu Acipenser composition；The investigation method of using method and using effect is with above.
Table 4 embodiment contrast groups C drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 10 | 44%(22) | 46%(23) | 10%(5) |
| Comparative example 11 | 38%(19) | 50%(25) | 12%(6) |
| Comparative example 12 | 40%(20) | 48%(24) | 12%(6) |
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3；This shows Chinese crude drug formula of the present invention
And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine
Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally
The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc.
Function, strengthens immune system ability；Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously
The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology
Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional
Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step
The preparation processing method of rapid E has had significant raising than traditional boiling method, the extraction degree of active ingredient.
Table 1 is compared with table 4:
The formula of embodiment contrast groups C does not contains Air Bladder pseudosciaenae seu Acipenser, and the invalid number of embodiment contrast groups C is 5 times of left sides of embodiment 1,2,3
Right；And effective percentage number has and has declined；Containing abundant collagen protein and omega 3 unsaturated fatty acid in Air Bladder pseudosciaenae seu Acipenser, right
Blood fat controls useful, can strengthen gastrointestinal digestive and absorptive functions, improves appetite, is conducive to preventing and treating inappetence, anorexia, digestion
The diseases such as bad, abdominal distention, constipation, show Air Bladder pseudosciaenae seu Acipenser serve in formula collaborative and priming return through effect, Air Bladder pseudosciaenae seu Acipenser is in formula
Application effect achieves unexpected technique effect.
In sum, a kind of replenishing YIN and removing heat the kidney invigorating beverage that the present invention provides has sour-sweet mouthfeel, has again simultaneously and controls
Treating high fever coma, xerostomia crimson tongue, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst；Food stagnation does not disappears, anorexia, in
Gas does not saves, the merit of fatigue, and all raw materials are all from medicine-food two-purpose natural plants, have no side effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (5)
1. a replenishing YIN and removing heat the kidney invigorating beverage, it is characterised in that be made up of the raw material of following weight portion: new fresh Herba Dendrobii 40-50, Portugal
Grape 25-35, Radix Codonopsis 3-10 part, Gypsum Fibrosum 3-60 part, Poria 3-10 part, Rhizoma Coptidis 2-9 part, Radix Scutellariae 3-5 part, Rhizoma Anemarrhenae 3-5 part, Radix Trichosanthis
5-10 part, Cortex Eucommiae 2-10 part, Fructus Lycii 2-10 part, Carapax et Plastrum Testudinis 10-30 part, Semen Cuscutae 10-20 part, Folium Eupatorii 1-10 part, Radix Ginseng 1-10
Part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, Mel, water are appropriate；
The preparation processing method of described a kind of replenishing YIN and removing heat the kidney invigorating beverage, comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add Herba Dendrobii for the first time fresh
The Chinese liquor of alcohol content 52-60 DEG C of bar weight 0.1-0.5 times, time 10-15min, the rotating speed of juice extractor is 20～30r/s；
After standing 10 minutes, adding the distilled water of Herba Dendrobii fresh bar weight 2-3 times, juice extractor time 10-15min for the second time, juice extractor turns
Speed is 80～100r/s, stands 10min；After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, the time
20-30min, juice extractor rotating speed is 100～150r/s, is separated with fiber filter by fresh for Herba Dendrobii bar juice, makes the fibre of the fresh bar of Herba Dendrobii
Dimension separation rate reaches more than 95%, and broken cell rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；Again by fresh
Fructus Vitis viniferae is put into after the warm water of 50-60 DEG C cleans up, and obtains Fructus Vitis viniferae meat and Pericarpium Vitis viniferae；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
F, take Radix Codonopsis, Gypsum Fibrosum, Poria, Rhizoma Coptidis, Radix Scutellariae, the Rhizoma Anemarrhenae, Radix Trichosanthis, the Cortex Eucommiae, Fructus Lycii, Carapax et Plastrum Testudinis, Semen Cuscutae, Folium Eupatorii, people
After ginseng, Air Bladder pseudosciaenae seu Acipenser mix homogeneously add 30-60 DEG C of warm water soaking 10 minutes, putting into reach in freezer ,-10～-20 DEG C, freezing 10-20 divides
Clock, forms freezing medicine block, freezing medicine block boiling is extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120
DEG C, carry out infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；For the third time
Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, obtains matrix
Solution III is standby；
G, take Matrix Solution I through instantaneous high-temperature 150-160 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
H, three kinds of Matrix Solutions, after material-compound tank stirs, seal through bottle capper and load in vial, packaged glass
Bottle puts into temperature 150～200 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
A kind of replenishing YIN and removing heat the kidney invigorating beverage the most according to claim 1, it is characterised in that by the raw material system of following weight portion
Become: new fresh Herba Dendrobii 40, Fructus Vitis viniferae 25, Radix Codonopsis 3 parts, 3 parts of Gypsum Fibrosum, 3 parts of Poria, Rhizoma Coptidis 2 parts, Radix Scutellariae 3 parts, the Rhizoma Anemarrhenae 3 parts, Radix Trichosanthis 5
Part, the Cortex Eucommiae 2 parts, Fructus Lycii 2 parts, Carapax et Plastrum Testudinis 10 parts, Semen Cuscutae 10 parts, Folium Eupatorii 1 part, Radix Ginseng 1 part, 5 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water are appropriate.
A kind of replenishing YIN and removing heat the kidney invigorating beverage the most according to claim 1, it is characterised in that by the raw material system of following weight portion
Become: new fresh Herba Dendrobii 50, Fructus Vitis viniferae 35, Radix Codonopsis 10 parts, 60 parts of Gypsum Fibrosum, 10 parts of Poria, Rhizoma Coptidis 9 parts, Radix Scutellariae 5 parts, the Rhizoma Anemarrhenae 5 parts, variola
10 parts of powder, the Cortex Eucommiae 10 parts, Fructus Lycii 10 parts, Carapax et Plastrum Testudinis 30 parts, Semen Cuscutae 20 parts, Folium Eupatorii 10 parts, Radix Ginseng 10 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, honeybee
Honey, water are appropriate.
Preparation processing method the most according to claim 1, it is characterised in that step B) in, after new fresh grape cleans up,
Put into reach in freezer ,-10～-20 DEG C of freezings 5～10 minutes, make Fructus Vitis viniferae freeze, take out after nature thaws, then carry out Fructus Vitis viniferae meat
With Pericarpium Vitis viniferae detached job.
Preparation processing method the most according to claim 1, it is characterised in that step H) described in material-compound tank endobasal-body solution
I, Matrix Solution II, the weight proportion of Matrix Solution III are 3:0.2～1:0.5～2.
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| CN107348288A (en) * | 2017-08-23 | 2017-11-17 | 宁波甬基生物科技有限公司 | A kind of tonifying liver and kidney and strengthening bones and muscles Chinese herbal health-caring beverage and preparation method thereof |
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| CN107348288A (en) * | 2017-08-23 | 2017-11-17 | 宁波甬基生物科技有限公司 | A kind of tonifying liver and kidney and strengthening bones and muscles Chinese herbal health-caring beverage and preparation method thereof |
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