CN106173632A - A kind of resolving depression expels the heat-evil and adjusts liver sending down the abnormal ascending QI beverage and preparation processing method - Google Patents
A kind of resolving depression expels the heat-evil and adjusts liver sending down the abnormal ascending QI beverage and preparation processing method Download PDFInfo
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof containing fruit or vegetable juices
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
- Non-Alcoholic Beverages (AREA)
Abstract
The invention discloses a kind of resolving depression of the present invention to expel the heat-evil tune liver sending down the abnormal ascending QI beverage, be made up of the raw material of following weight portion: new fresh Herba Dendrobii 10 20 parts, Fructus Vitis viniferae 10 20 parts, new fresh Herba Dendrobii 10 20 parts, Fructus Vitis viniferae 10 20 parts, Lignum Aquilariae Resinatum 18 parts, the Radix Linderae 5 15 parts, Cortex Cinnamomi 15 parts, Rhizoma Coptidis 1 10 parts, the Radix Aucklandiae 1 10 parts, Radix Bupleuri 1 15 parts, DABAI 5 12 parts, Fructus Aurantii 10 15 parts, Radix Paeoniae Alba 16 parts, 10 15 parts of Radix Glycyrrhizae, Folium Eriobotryae 16 parts, Mel, water are appropriate.The invention have the advantage that the resolving depression that has of inventive formulation expels the heat-evil, adjusts the functions such as liver sending down the abnormal ascending QI, carry and drink conveniently, improving self and increase the wriggling of the intestines and stomach, cure the disease strengthens the beverage of body immunity simultaneously, and the shelf-life is up to 12 years.
Description
Technical field
The present invention relates to a kind of resolving depression expel the heat-evil tune liver sending down the abnormal ascending QI beverage, in particular, relate to a kind of resolving depression and expel the heat-evil tune liver
Sending down the abnormal ascending QI drink formula and preparation method thereof technical field.
Background technology
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, and does not have resolving depression and expels the heat-evil, adjusts the functions such as liver sending down the abnormal ascending QI, nothing
Method releases the sufferings of client, and traditional herbal tea is by Traditional medicine infusion, and flavour of a drug weight mouthfeel is poor, it is impossible to preserve for a long time.Existing market
On not yet occur a kind of in good taste, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously.
Summary of the invention
The present invention is directed to the deficiency of existing product, and provide a kind of fresh juice beverage to regulate the effect of human physiological functions,
This beverage have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach,
Cure the disease and strengthen a kind of resolving depression of the advantage such as body immunity simultaneously and expel the heat-evil tune liver sending down the abnormal ascending QI beverage.
A kind of resolving depression of the present invention expels the heat-evil and adjusts liver sending down the abnormal ascending QI beverage, is made up of the raw material of following weight portion: new fresh Herba Dendrobii 10-20
Part, Fructus Vitis viniferae 10-20 part, Lignum Aquilariae Resinatum 1-8 part, Radix Linderae 5-15 part, Cortex Cinnamomi 1-5 part, Rhizoma Coptidis 1-10 part, Radix Aucklandiae 1-10 part, Radix Bupleuri 1-15
Part, Fructus Aurantii 10-15 part, Radix Paeoniae Alba 1-6 part, Radix Glycyrrhizae 10-15 part, Folium Eriobotryae 1-6 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, Mel, water are appropriate；
Described a kind of resolving depression expels the heat-evil and adjusts the preparation processing method of liver sending down the abnormal ascending QI beverage, comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take Lignum Aquilariae Resinatum, the Radix Linderae, Cortex Cinnamomi, Rhizoma Coptidis, the Radix Aucklandiae, Radix Bupleuri, Fructus Aurantii, Radix Paeoniae Alba, Radix Glycyrrhizae, Folium Eriobotryae, Air Bladder pseudosciaenae seu Acipenser mix homogeneously add 30-
60 DEG C of warm water soaking, after 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine block, by cold
Freezing medicine block boiling to extract 3 times, add 1-2 times amount water for the first time, temperature keeps 100-120 DEG C, carries out infusion 10-20 minute；
Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times amount water, and temperature keeps
120-150 DEG C, carry out infusion 30 minutes, filter, be concentrated into the 1/2 of original volume, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer, at the freezing 5-10 in-10～-20 DEG C
Minute, make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Further: step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion be 10:0.2～0.8:5～10:0.5.
Lignum Aquilariae Resinatum, acrid in the mouth, hardship, warm in nature；Return spleen, stomach, kidney channel;Gas perfume (or spice) row dissipates, and drops and can rise；There is circulation of qi promoting warming middle-JIAO to send down the adverse QI, warm
Effect of kidney helping inspiration to relieve asthma.
The Radix Linderae, the pungent temperature of the property of medicine.Return lung, spleen, kidney, bladder warp, pleasant resolving depression, dispersing cold for relieving pain, can be used for inverse chest and abdomen swelling and pain, place
Food does not disappears, food is vomitted in regurgitation.
Cortex Cinnamomi, complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.
Rhizoma Coptidis, heat clearing and damp drying, eliminating fire and detoxication, for damp and hot feeling of fullness, vomit, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire,
Dysphoria and insomnia.
The Radix Aucklandiae, the abdominal distention caused by stagnation of QI in spleen and stomach, lack of appetite vomiting, the hypochondriac pain caused for QI stagnation of the liver and galibladder, spleen invigorating disappears stagnant.
The stagnant gas of adjustable gastrointestinal.
Radix Bupleuri, acrid in the mouth, hardship, cold nature.Reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang, preventing the attack (or recurrence) of malaria of bringing down a fever, for cold, fever,
Alternate attack of chill and fever, distending pain in the chest and hypochondrium.
Fructus Aurantii, regulating the flow of QI to ease the stomach, the stagnant relieving distension of row, control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, weight after dysentery.
Radix Paeoniae Alba, its cold nature, bitter in the mouth, acid.Function is suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.
Folium Eriobotryae, has clearing away lung-heat to relieve cough, regulating the stomach and sending down the abnormal ascending QI, the effect quenched the thirst.
Radix Glycyrrhizae, and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.
The natural tradition medicinal and edible Chinese medicine above with multiple health care is share, there is resolving depression and expel the heat-evil, adjust liver to drop
Inverse effect, has depression of liver-QI, disorder of movement of QI, the merit of dyspnea due to adverse flow of lung-QI breath.The proportioning of each component, science is screened by great many of experiments
Rationally；And whole preparation technology is rationally and extract drugs rate efficiency is high, can retain the effective ingredient in raw material well, without
Enter any impurity, have no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines
Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported
Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax
Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong anti-oxidation, resist
Suddenly change, alleviate the function such as hepatosis, protection cardiovascular；
3, add the Chinese herbal medicine such as Lignum Aquilariae Resinatum, the Radix Linderae, Cortex Cinnamomi, Rhizoma Coptidis, the Radix Aucklandiae, Radix Bupleuri, Fructus Aurantii, Radix Paeoniae Alba, Radix Glycyrrhizae, Folium Eriobotryae and there is tonification
The functions such as lung spleen, eliminating phlegm sending down the abnormal ascending QI.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has
The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and
Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1-
2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
A kind of resolving depression expels the heat-evil tune liver sending down the abnormal ascending QI beverage, is made up of the raw material of following weight portion: new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, heavy
Perfume 5 parts, the Radix Linderae 6 parts, Cortex Cinnamomi 4 parts, Rhizoma Coptidis 4 parts, the Radix Aucklandiae 4 parts, Radix Bupleuri 4 parts, Fructus Aurantii 12 parts, Radix Paeoniae Alba 4 parts, 12 parts of Radix Glycyrrhizae, Folium Eriobotryae
4 parts of leaf, 5 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water are appropriate；
A kind of resolving depression expels the heat-evil and adjusts the preparation processing method of liver sending down the abnormal ascending QI beverage, and described preparation method comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
Fresh for the Herba Dendrobii cleaned up bar is put into microwave oven by B, keeps temperature 50-60 DEG C, carries out heating 10 minutes, further take out
Put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content 52 of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
DEG C Chinese liquor, time 15min, the rotating speed of juice extractor is 30r/s；After standing 10 minutes, add the steaming of Herba Dendrobii fresh bar weight 2.5 times
Distilled water, for the second time juice extractor time 15min, juice extractor rotating speed is 80r/s, stands 10min；After carry out third time squeeze the juice, add
The distilled water of Herba Dendrobii fresh bar weight 3-5 times, time 30min, juice extractor rotating speed is 150r/s, by fresh for Herba Dendrobii bar juice and fiber mistake
Filter separate, make the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, broken cell rate reaches more than 80%, obtain new fresh Herba Dendrobii juice and
Herba Dendrobii fresh bar fiber；Again new fresh grape is put into after the warm water of 55 DEG C cleans up, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated
Stand-by；After new fresh grape cleans up, put into reach in freezer ,-10 ~-20 DEG C of freezings 10 minutes, make Fructus Vitis viniferae freeze, take out certainly
After so thawing, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 120 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 6 times of weight, stirring is smashed to 100 mesh, 30-35 DEG C of temperature
Degree lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby；Extract the Fructus Vitis viniferae after Matrix Solution
It is the cellulase of 0.5-0.7% that skin and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, keeps
35 DEG C, water soluble dietary fiber can be extracted after 24h enzymolysis further, water soluble dietary fiber is added Matrix Solution and obtains
Matrix Solution II；；Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to protection human body is from the damage of free radical, it is possible to enhancing blood vessel elasticity,
Lax blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong antioxygen
Change, mutation, alleviate hepatosis, protection function, Pericarpium Vitis viniferae and the Herba Dendrobii fresh bar fiber such as cardiovascular together with stir smash through
Anthocyanidin mentioned by hydromel, can protect the quality of anthocyanidin while farthest extracting anthocyanidin.By water solublity meals
Food fiber adds Matrix Solution and obtains Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged
External；Adsorb various metabolic waste, be allowed to normally excrete, improve the comprehensive utilization value of Herba Dendrobii.
E, take Lignum Aquilariae Resinatum, the Radix Linderae, Cortex Cinnamomi, Rhizoma Coptidis, the Radix Aucklandiae, Radix Bupleuri, Fructus Aurantii, Radix Paeoniae Alba, Radix Glycyrrhizae, Folium Eriobotryae, Air Bladder pseudosciaenae seu Acipenser mix homogeneously
After adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C of freezings 20 minutes, form freezing medicine block, will
Freezing medicine block boiling is extracted 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out infusion 10-20 and divides
Clock；Second time adds 6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times amount water, and temperature is protected
Hold 120-150 DEG C, carry out infusion 30 minutes, filter, be concentrated into the 1/2 of original volume, obtain Matrix Solution III standby；Chinese medicine warp
After foaming is good after freezing, cell wall crystallization ruptures, and forms freezing medicine block, then makes the composition maximum journey of Chinese medicine through high temperature infusion
The extraction of degree.
F, take Matrix Solution I through instantaneous high-temperature 120 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；Supercritical extraction can be
Extract under room temperature 37 DEG C and CO2 gas blanket, effectively prevent oxidation and the loss of heat-sensitive substance.Therefore,
The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the easy material being pyrolyzed the lowest
Extract under its boiling temperature；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, and described material-compound tank endobasal-body solution I, matrix are molten
Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5., seal through bottle capper and load vial
In, packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, dress
Case, carries and drinks conveniently, and the shelf-life is up to 1-2.
Embodiment 2
A kind of resolving depression expels the heat-evil and adjusts liver sending down the abnormal ascending QI beverage, is made up of the raw material of following weight portion: be made up of the raw material of following weight portion: by
The raw material of following weight portion is made: new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Lignum Aquilariae Resinatum 1 part, the Radix Linderae 5 parts, Cortex Cinnamomi 1 part, Rhizoma Coptidis 1 part, wood
Fragrant 1 part, Radix Bupleuri 1 part, Fructus Aurantii 10 parts, Radix Paeoniae Alba 1 part, 10 parts of Radix Glycyrrhizae, Folium Eriobotryae 1 part, 5 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water appropriate；Processing side
Method is with embodiment 1.
Embodiment 3
A kind of resolving depression expels the heat-evil and adjusts liver sending down the abnormal ascending QI beverage, is made up of the raw material of following weight portion: be made up of the raw material of following weight portion: new
Fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Lignum Aquilariae Resinatum 8 parts, the Radix Linderae 15 parts, Cortex Cinnamomi 5 parts, Rhizoma Coptidis 10 parts, the Radix Aucklandiae 10 parts, Radix Bupleuri 15 parts, Fructus Aurantii
15 parts, Radix Paeoniae Alba 6 parts, 15 parts of Radix Glycyrrhizae, Folium Eriobotryae 6 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water appropriate；Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding
Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days；In 7 days, mice is without death, OK
For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception,
Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not
See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that three kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100,
50g；Experimental mouse is randomly divided into three groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal
General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart,
The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach；
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no
Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach
Deng the most significant change, it is understood that through proved by pathology, three kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is
Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 20 days
3. number is drunk: 50 people
4. drinking method: 3 times for each person every day, each 300mL
5. index: after drinking, substantially sensation easily fatigue, depression of liver-QI, disorder of movement of QI, dyspnea due to adverse flow of lung-QI breath, food stagnation do not disappear, do not think drink
The transference cures such as food, middle gas not province, and mouthfeel is the most sour-sweet for effective；After drinking, sensation easily fatigue, depression of liver-QI, mechanism of qi lose
Adjust, dyspnea due to adverse flow of lung-QI ceases；Food stagnation does not disappears, anorexia, middle gas do not save remission, and mouthfeel is the most sour-sweet, is designated as effectively.After drinking
It is invalid to be then designated as without obvious comfort.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried
The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially
Increase comfort.
The each embodiment of table 1 drinks effect research table
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Embodiment 1 | 44%(22) | 54%(27) | 2%(1) |
| Embodiment 2 | 42%(21) | 56%(28) | 2%(1) |
| Embodiment 3 | 42%(21) | 56%(28) | 2%(1) |
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling
Method；The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 4 | 36%(18) | 40%(20) | 24%(12) |
| Comparative example 5 | 40%(20) | 40%(20) | 20%(10) |
| Comparative example 6 | 46%(23) | 34%(17) | 20%(10) |
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1
The preparation processing method of step E；The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 7 | 32%(16) | 56%(28) | 12%(6) |
| Comparative example 8 | 28%(14) | 52%(31) | 10%(5) |
| Comparative example 9 | 36%(18) | 52%(26) | 12%(6) |
Embodiment contrast groups C
The processing method of comparative example 10,11,12 respectively corresponding embodiment 1,2,3 and formula, different be formula in
Without Air Bladder pseudosciaenae seu Acipenser composition；The investigation method of using method and using effect is with above.
Table 4 embodiment contrast groups C drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 10 | 44%(22) | 46%(23) | 10%(5) |
| Comparative example 11 | 38%(19) | 50%(25) | 12%(6) |
| Comparative example 12 | 40%(20) | 48%(24) | 12%(6) |
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3；This shows Chinese crude drug formula of the present invention
And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine
Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally
The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc.
Function, strengthens immune system ability；Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously
The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology
Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional
Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step
The preparation processing method of rapid E has had significant raising than traditional boiling method, the extraction degree of active ingredient.
Table 1 is compared with table 4:
The formula of embodiment contrast groups C does not contains Air Bladder pseudosciaenae seu Acipenser, and the invalid number of embodiment contrast groups C is 5 times of left sides of embodiment 1,2,3
Right；And effective percentage number has and has declined；Containing abundant collagen protein and omega 3 unsaturated fatty acid in Air Bladder pseudosciaenae seu Acipenser, right
Blood fat controls useful, can strengthen gastrointestinal digestive and absorptive functions, improves appetite, is conducive to preventing and treating inappetence, anorexia, digestion
The diseases such as bad, abdominal distention, constipation, show Air Bladder pseudosciaenae seu Acipenser serve in formula collaborative and priming return through effect, Air Bladder pseudosciaenae seu Acipenser is in formula
Application effect achieves unexpected technique effect.
In sum, a kind of resolving depression that the present invention provides expels the heat-evil and adjusts liver sending down the abnormal ascending QI beverage to have sour-sweet mouthfeel, has again simultaneously
There are treatment easily fatigue, depression of liver-QI, disorder of movement of QI, dyspnea due to adverse flow of lung-QI ceases, food stagnation does not disappears, anorexia, middle gas do not save merit.And institute
There is raw material to be all from medicine-food two-purpose natural plants, have no side effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (5)
1. a resolving depression expels the heat-evil and adjusts liver sending down the abnormal ascending QI beverage, it is characterised in that be made up of the raw material of following weight portion: new fresh Herba Dendrobii 10-
20 parts, Fructus Vitis viniferae 10-20 part, Lignum Aquilariae Resinatum 1-8 part, Radix Linderae 5-15 part, Cortex Cinnamomi 1-5 part, Rhizoma Coptidis 1-10 part, Radix Aucklandiae 1-10 part, Radix Bupleuri 1-
15 parts, Fructus Aurantii 10-15 part, Radix Paeoniae Alba 1-6 part, Radix Glycyrrhizae 10-15 part, Folium Eriobotryae 1-6 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, Mel, water appropriate；
Described a kind of resolving depression expels the heat-evil and adjusts the preparation processing method of liver sending down the abnormal ascending QI beverage, comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take Lignum Aquilariae Resinatum, the Radix Linderae, Cortex Cinnamomi, Rhizoma Coptidis, the Radix Aucklandiae, Radix Bupleuri, DABAI, Fructus Aurantii, Radix Paeoniae Alba, Radix Glycyrrhizae, Folium Eriobotryae, Air Bladder pseudosciaenae seu Acipenser；Mixing is all
Even add 30-60 DEG C of warm water soaking 10 minutes after, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine
Block, extracts freezing medicine block boiling 3 times, adds 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out infusion 10-
20 minutes；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times amount water,
Temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, obtains Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
A kind of resolving depression the most according to claim 1 expels the heat-evil and adjusts liver sending down the abnormal ascending QI beverage, it is characterised in that step B) in, fresh Portugal
After grape clean up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute, make Fructus Vitis viniferae freeze, take out after nature thaws,
Carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job again.
A kind of resolving depression the most according to claim 1 expels the heat-evil tune liver sending down the abnormal ascending QI beverage, it is characterised in that step H) described in dispensing
Tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.2～0.8:5～10:
0.5。
A kind of resolving depression the most according to claim 1 expels the heat-evil tune liver sending down the abnormal ascending QI beverage, it is characterised in that former by following weight portion
Material is made: new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Lignum Aquilariae Resinatum 1 part, the Radix Linderae 5 parts, Cortex Cinnamomi 1 part, Rhizoma Coptidis 1 part, the Radix Aucklandiae 1 part, Radix Bupleuri 1 part,
Fructus Aurantii 10 parts, Radix Paeoniae Alba 1 part, 10 parts of Radix Glycyrrhizae, Folium Eriobotryae 1 part, 5 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water are appropriate.
A kind of resolving depression the most according to claim 1 expels the heat-evil tune liver sending down the abnormal ascending QI beverage, it is characterised in that former by following weight portion
Material is made: new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Lignum Aquilariae Resinatum 8 parts, the Radix Linderae 15 parts, Cortex Cinnamomi 5 parts, Rhizoma Coptidis 10 parts, the Radix Aucklandiae 10 parts, Radix Bupleuri
15 parts, Fructus Aurantii 15 parts, Radix Paeoniae Alba 6 parts, 15 parts of Radix Glycyrrhizae, Folium Eriobotryae 6 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water appropriate.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
Non-Patent Citations (2)
| Title |
|---|
| 宋芳等: "超临界二氧化碳萃取葡萄籽油及其脂肪酸的分析", 《中国食品工业》 * |
| 李文亮等: "《千家妙方上》", 31 July 1982, 战士出版社 * |
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