CN106173036A - The medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia and preparation processing method - Google Patents
The medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia and preparation processing method Download PDFInfo
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- CN106173036A CN106173036A CN201610234286.9A CN201610234286A CN106173036A CN 106173036 A CN106173036 A CN 106173036A CN 201610234286 A CN201610234286 A CN 201610234286A CN 106173036 A CN106173036 A CN 106173036A
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Abstract
The invention discloses the medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia of the present invention, be made up of the raw material of following weight portion: Radix Codonopsis 5 15 parts, the Radix Astragali 5 12 parts, 5 10 parts of Poria, Semen Vaccariae 10 16 parts, Herba Artemisiae Anomalae 5 15 parts, Squama Manis 6 15 parts, Caulis Akebiae 5 10 parts, Semen Plantaginis 5 10 parts, Bi 5 10 parts, Cortex Cinnamomi 5 10 parts, Herba Cistanches 5 10 parts, 5 10 parts of Radix Rehmanniae Preparata, Folium Pyrrosiae 5 10 parts, poultry 5 10 parts, Fructus Ailanthi 5 10 parts, Medulla Junci 5 10 parts.The invention have the advantage that inventive formulation clearing away damp-heat temperature, kidney-replenishing, replenishing QI to invigorate the spleen, diuresis promoting treat prostate hyperplasia, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.
Description
Technical field
The present invention relates to the medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia, in particular, relate to one
The herb tea formula planting clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia and preparation method thereof technical field.
Background technology
Prostate hyperplasia onset is slow, and middle-aged male watches out for prostate hyperplasia, and the symptom of prostate hyperplasia includes: uroflow without
Power, sensation intravesical still leave urine do not drain, have any problem when starting to urinate, pollakiuria, urgent micturition, when prostatauxe situation gradually
Gradually serious, urethra will be caused intravesical urine not discharge by bigger pressure.In minority male, prostatauxe
The obstruction caused can cause repeated infection, causes dysuria and long calculus.
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, do not have clearing away damp-heat temperature, kidney-replenishing, replenishing QI to invigorate the spleen,
Diuresis promoting treatment prostate hyperplasia, raising body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, fall three-hypers, preventing and treating sugar
The sick function with aspects such as giving protection against cancer, anticancer of urine, it is impossible to release the sufferings of client, and traditional herbal tea is by Traditional medicine infusion, flavour of a drug
Weight mouthfeel is poor, it is impossible to preserve for a long time.The most not yet occur a kind of in good taste, improve self and increase the wriggling of the intestines and stomach, control
The sick beverage simultaneously strengthening body immunity.
Summary of the invention
The present invention is directed to the deficiency of existing product, and provide a kind of fresh juice beverage to regulate the effect of human physiological functions,
This beverage have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach,
Cure the disease the medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia simultaneously strengthening the advantage such as body immunity.
The medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia, is made up of the raw material of following weight portion: Radix Codonopsis 5-
15 parts, Radix Astragali 5-12 part, Poria 5-10 part, Semen Vaccariae 10-16 part, Herba Artemisiae Anomalae 5-15 part, Squama Manis 6-15 part, Caulis Akebiae 5-10
Part, Semen Plantaginis 5-10 part, Bi 5-10 part, Cortex Cinnamomi 5-10 part, Herba Cistanches 5-10 part, Radix Rehmanniae Preparata 5-10 part, Folium Pyrrosiae 5-10 part, poultry
5-10 part, Fructus Ailanthi 5-10 part, Medulla Junci 5-10 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel,
Water is appropriate.
The preparation processing method of the medicated tea of described a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia, including following step
Suddenly；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Medulla Junci cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, each 2 little
Time, merging 2 Medulla Junci ethanol extracts, stand precipitate with ethanol, filter, filtrate is concentrated into without alcohol taste, and is evaporated at 40 DEG C
Relative density is 1.15-1.35, and the extract preparing Medulla Junci is standby；
Bi, Cortex Cinnamomi, Herba Cistanches, Radix Rehmanniae Preparata, Folium Pyrrosiae, poultry, Fructus Ailanthi mix and blend are put into super micron mill, super micron mill
Heating keeps temperature 80 degree 5-6 minute, carries out micronizing and obtains the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro
Mixing fine powders quality 6～the distilled water of 8 times, first soak 10min～15min, pour in volatile oil extractor, and the way of distillation is extracted and waved
Hair oil 2～4h, it is thus achieved that volatile oil and ultra micro mixing fine powders medicinal residues；
Taking Radix Codonopsis, the Radix Astragali, Poria, Semen Vaccariae, Herba Artemisiae Anomalae, Squama Manis, Caulis Akebiae, Semen Plantaginis, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously adds 30-60 DEG C
After warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine block, by freezing medicine
Block and ultra micro mixing fine powders medicinal residues boiling are extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out
Infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10
Times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, and is concentrated into the 1/2 of original volume, adds Medulla Junci
Extract and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute,
Make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Further: step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion be 10:0.2～0.8:5～10:0.5.
Radix Codonopsis, sweet, flat.Invigorating the spleen and replenishing QI, stomach function regulating promotes the production of body fluid, expelling phlegm for arresting cough, for weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength,
Lack of appetite, thirsty.
The Radix Astragali, returns lung, spleen, liver, kidney channel.Enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and
Wide antibacterial action.
Poria, sweet in the mouth, light, property is put down, GUIXIN, lung, spleen, kidney channel, promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.
Semen Vaccariae, has promoting blood circulation to restore menstrual flow, and stimulating milk secretion is subsided a swelling, effect of inducing diuresis for treating stranguria syndrome.
Herba Artemisiae Anomalae, has hemostasis of curing the wound, and removing blood stasis stimulates the menstrual flow, promoting digestion and removing stagnation, the effect of appetizing of being amusing.
Squama Manis, has the functions such as promoting blood circulation to remove obstruction in the collateral, detumescence and apocenosis, wind-expelling pain-stopping, lactogenesis.
Caulis Akebiae, pathogenic fire purging row water, promoting blood circulation, control hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia.
Bi, distinguishing is turbid, warming kidney and eliminating damp, treatment nephritis, chyluria, renal tuberculosis merge hematuria, chronic prostatitis.
Cortex Cinnamomi, complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.
Herba Cistanches, for impotence due to deficiency of the kidney, seminal emission premature ejaculation and chills and pain of the waist and kness, muscles and bones convulsion is weak.
Radix Rehmanniae Preparata, sweet, tepor.Returning liver, kidney channel, yin nourishing of enriching blood, life essence-filling, marrow-benefitting, sweet Wen Zhirun, nourishing YIN benefit essence is with hemopoietic.
Folium Pyrrosiae, relieving stranguria by diuresis, lung heat clearing such as expels the heat-evil at the effect.Can be used for drenching pain, hematuria, lithangiuria, nephritis, metrorrhagia, dysentery
Poultry, bitter, flat, enter stomach, bladder warp, clearing away heat and promoting diuresis is treating stranguria, inducing diuresis for treating stranguria syndrome: for acute cystitis, the urine of urethritis
Deficient puckery pain.
Fructus Ailanthi, bitter in the mouth, puckery, cool in nature, heat clearing and damp drying, dysentery relieving, hemostasis.Cure mainly dysentery, nebulousurine, leukorrhagia, have blood in stool, hematuria,
Metrorrhagia.
Medulla Junci, relieving stranguria by diuresis;Clearing heart fire.The puckery pain of gonorrhea, edema, dysuria, oliguria.
Fructus Vitis viniferae is the most delicious and tasty, and nutritive value is the highest, containing mineral calcium, potassium, phosphorus, ferrum and multiple in Fructus Vitis viniferae
Vitamin B1, vitamin B2, vitamin B6, vitamin C and Citrin etc., possibly together with the aminoacid of multiple needed by human body, multiple
Fruit acid contributes to digestion, suitably eats a little Fructus Vitis viniferae more, can be good for Pi stomach function regulating, and to neurasthenia, overfatigue is of great advantage and has.
The natural tradition medicinal and edible Chinese medicine above with multiple health care is share, clearing away damp-heat temperature, kidney-replenishing, QI invigorating
Spleen invigorating, diuresis promoting treatment prostate hyperplasia, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, resisting fatigue it
Merit.The proportioning of each component is screened by great many of experiments, scientific and reasonable；And whole preparation technology is reasonable and extract drugs rate efficiency
Height, can retain the effective ingredient in raw material well, does not bring any impurity, and sweet mouthfeel into, has no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines
Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported
Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax
Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong anti-oxidation, resist
Suddenly change, alleviate the function such as hepatosis, protection cardiovascular；
3, add the Chinese herbal medicine such as Radix Codonopsis, the Radix Astragali, Poria, Semen Vaccariae, Herba Artemisiae Anomalae, Squama Manis, Caulis Akebiae, Semen Plantaginis and there is clearing away damp-heat
Temperature, kidney-replenishing, replenishing QI to invigorate the spleen, diuresis promoting treatment prostate hyperplasia, improves body immunity, defying age, eliminating toxin and beautifying the skin, nourishing
The function such as taste, resisting fatigue.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has
The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and
Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1-
2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
The medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia, is made up of the raw material of following weight portion: Radix Codonopsis 8 parts, Huang
Stilbene 8 parts, 8 parts of Poria, Semen Vaccariae 12 parts, Herba Artemisiae Anomalae 12 parts, Squama Manis 12 parts, Caulis Akebiae 8 parts, Semen Plantaginis 8 parts, Bi 8 parts, Cortex Cinnamomi
8 parts, Herba Cistanches 8 parts, 8 parts of Radix Rehmanniae Preparata, Folium Pyrrosiae 8 parts, poultry 6 parts, Fructus Ailanthi 6 parts, Medulla Junci 5 parts, 8 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 15
Part, Fructus Vitis viniferae 15 parts, Mel, water are appropriate.
The preparation processing method of the medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia, described preparation method includes
Following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
Fresh for the Herba Dendrobii cleaned up bar is put into microwave oven by B, keeps temperature 50-60 DEG C, carries out heating 10 minutes, further take out
Put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content 52 of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
DEG C Chinese liquor, time 15min, the rotating speed of juice extractor is 30r/s；After standing 10 minutes, add the steaming of Herba Dendrobii fresh bar weight 2.5 times
Distilled water, for the second time juice extractor time 15min, juice extractor rotating speed is 80r/s, stands 10min；After carry out third time squeeze the juice, add
The distilled water of Herba Dendrobii fresh bar weight 3-5 times, time 30min, juice extractor rotating speed is 150r/s, by fresh for Herba Dendrobii bar juice and fiber mistake
Filter separate, make the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, broken cell rate reaches more than 80%, obtain new fresh Herba Dendrobii juice and
Herba Dendrobii fresh bar fiber；Again new fresh grape is put into after the warm water of 55 DEG C cleans up, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated
Stand-by；After new fresh grape cleans up, put into reach in freezer ,-10 ~-20 DEG C of freezings 10 minutes, make Fructus Vitis viniferae freeze, take out certainly
After so thawing, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 120 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 6 times of weight, stirring is smashed to 100 mesh, 30-35 DEG C of temperature
Degree lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby；Extract the Fructus Vitis viniferae after Matrix Solution
It is the cellulase of 0.5-0.7% that skin and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, keeps
35 DEG C, water soluble dietary fiber can be extracted after 24h enzymolysis further, water soluble dietary fiber is added Matrix Solution and obtains
Matrix Solution II；Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to protection human body is from the damage of free radical, it is possible to enhancing blood vessel elasticity,
Lax blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong antioxygen
Change, mutation, alleviate hepatosis, protection function, Pericarpium Vitis viniferae and the Herba Dendrobii fresh bar fiber such as cardiovascular together with stir smash through
Anthocyanidin mentioned by hydromel, can protect the quality of anthocyanidin while farthest extracting anthocyanidin.By water solublity meals
Food fiber adds Matrix Solution and obtains Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged
External；Adsorbing various metabolic waste, be allowed to normally excrete, the comprehensive utilization value improving Herba Dendrobii improves human body centering simultaneously
The absorption of medicine composition.
E, take mix homogeneously after Medulla Junci cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, each 2
Hour, merging 2 Medulla Junci ethanol extracts, stand precipitate with ethanol, filter, filtrate is concentrated into without alcohol taste, and is evaporated to 40 DEG C
Lower relative density is 1.15-1.35, and the extract preparing Medulla Junci is standby；
Bi, Cortex Cinnamomi, Herba Cistanches, Radix Rehmanniae Preparata, Folium Pyrrosiae, poultry, Fructus Ailanthi mix and blend are put into super micron mill, super micron mill
Heating keeps temperature 80 degree 5-6 minute, carries out micronizing and obtains the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro
Mixing fine powders quality 6～the distilled water of 8 times, first soak 10min～15min, pour in volatile oil extractor, and the way of distillation is extracted and waved
Hair oil 2～4h, it is thus achieved that volatile oil and ultra micro mixing fine powders medicinal residues；
Taking Radix Codonopsis, the Radix Astragali, Poria, Semen Vaccariae, Herba Artemisiae Anomalae, Squama Manis, Caulis Akebiae, Semen Plantaginis, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously adds 30-60 DEG C
After warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine block, by freezing medicine
Block and ultra micro mixing fine powders medicinal residues boiling are extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out
Infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10
Times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, and is concentrated into the 1/2 of original volume, adds Medulla Junci
Extract and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 120 DEG C, 1-2 minute, put into material-compound tank；Taking Matrix Solution II through mesh number is
Material-compound tank is put into after the fine filter filter of 100 mesh；Take Matrix Solution III again and put into dispensing after the fine filter filter that mesh number is 60 mesh
In tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；Supercritical extraction can be
Extract under room temperature 37 DEG C and CO2 gas blanket, effectively prevent oxidation and the loss of heat-sensitive substance.Therefore,
The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the easy material being pyrolyzed the lowest
Extract under its boiling temperature；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, and described material-compound tank endobasal-body solution I, matrix are molten
Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5.Sealing through bottle capper loads in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning,
Carrying and drink conveniently, the shelf-life is up to 1-2.
Embodiment 2
The medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia, is made up of the raw material of following weight portion: Radix Codonopsis 5 parts, Huang
Stilbene 5 parts, 5 parts of Poria, Semen Vaccariae 10 parts, Herba Artemisiae Anomalae 5 parts, Squama Manis 6 parts, Caulis Akebiae 5 parts, Semen Plantaginis 5 parts, Bi 5 parts, Cortex Cinnamomi 5
Part, Herba Cistanches 5 parts, 5 parts of Radix Rehmanniae Preparata, Folium Pyrrosiae 5 parts, poultry 5 parts, Fructus Ailanthi 5 parts, Medulla Junci 5 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 10
Part, Fructus Vitis viniferae 10 parts, Mel, water are appropriate.Processing method is with embodiment 1.
Embodiment 3
The medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia, is made up of the raw material of following weight portion: Radix Codonopsis 15 parts, Huang
Stilbene 12 parts, 10 parts of Poria, Semen Vaccariae 16 parts, Herba Artemisiae Anomalae 15 parts, Squama Manis 15 parts, Caulis Akebiae 10 parts, Semen Plantaginis 10 parts, Bi 10
Part, Cortex Cinnamomi 10 parts, Herba Cistanches 10 parts, 10 parts of Radix Rehmanniae Preparata, Folium Pyrrosiae 10 parts, poultry 10 parts, Fructus Ailanthi 10 parts, Medulla Junci 10 parts, Air Bladder pseudosciaenae seu Acipenser
10 parts, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Mel, water appropriate.Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding
Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days；In 7 days, mice is without death, OK
For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception,
Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not
See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that three kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100,
50g；Experimental mouse is randomly divided into three groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal
General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart,
The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach；
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no
Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach
Deng the most significant change, it is understood that through proved by pathology, three kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is
Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 120 days
3. number is drunk: 50 people
4. drinking method: 600mL for each person every day
5. index: obvious prostate hyperplasia urine retention, dysuria, feeling of distension and oppression dark coloured urine, tired mind, inappetence etc. after drinking
Transference cure, and mouthfeel is the most sour-sweet for effective；Drink rear prostate hyperplasia urine retention, dysuria, feeling of distension and oppression dark coloured urine, spirit tired
The remissions such as idle, inappetence, and mouthfeel is the most sour-sweet, is designated as effectively.It is invalid to be then designated as without obvious comfort after drinking.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried
The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially
Increase comfort.
The each embodiment of table 1 drinks effect research table
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Embodiment 1 | 44%(22) | 54%(27) | 2%(1) |
| Embodiment 2 | 42%(21) | 56%(28) | 2%(1) |
| Embodiment 3 | 42%(21) | 56%(28) | 2%(1) |
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling
Method；The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 4 | 36%(18) | 40%(20) | 24%(12) |
| Comparative example 5 | 40%(20) | 40%(20) | 20%(10) |
| Comparative example 6 | 46%(23) | 34%(17) | 20%(10) |
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1
The preparation processing method of step E；The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 7 | 32%(16) | 56%(28) | 12%(6) |
| Comparative example 8 | 28%(14) | 52%(31) | 10%(5) |
| Comparative example 9 | 36%(18) | 52%(26) | 12%(6) |
Embodiment contrast groups C
The processing method of comparative example 10,11,12 respectively corresponding embodiment 1,2,3 and formula, different be formula in
Without Air Bladder pseudosciaenae seu Acipenser composition；The investigation method of using method and using effect is with above.
Table 4 embodiment contrast groups C drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 10 | 44%(22) | 46%(23) | 10%(5) |
| Comparative example 11 | 38%(19) | 50%(25) | 12%(6) |
| Comparative example 12 | 40%(20) | 48%(24) | 12%(6) |
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3；This shows Chinese crude drug formula of the present invention
And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine
Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally
The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc.
Function, strengthens immune system ability；Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously
The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology
Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional
Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step
The preparation processing method of rapid E has had significant raising than traditional boiling method, the extraction degree of active ingredient.
Table 1 is compared with table 4:
The formula of embodiment contrast groups C does not contains Air Bladder pseudosciaenae seu Acipenser, and the invalid number of embodiment contrast groups C is 5 times of left sides of embodiment 1,2,3
Right；And effective percentage number has and has declined；Show Air Bladder pseudosciaenae seu Acipenser serve in formula collaborative and priming return through effect, Air Bladder pseudosciaenae seu Acipenser should
Unexpected technique effect is achieved by effect.
In sum, the medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia that the present invention provides, clearing away damp-heat temperature,
Kidney-replenishing, replenishing QI to invigorate the spleen, diuresis promoting treatment prostate hyperplasia, has a sour-sweet mouthfeel, improve body immunity, defying age,
Eliminating toxin and beautifying the skin, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful.And all raw materials is all from
Medicine-food two-purpose natural plants, has no side effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (7)
1. the medicated tea of a clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia, it is characterised in that by the raw material system of following weight portion
Become: Radix Codonopsis 5-15 part, Radix Astragali 5-12 part, Poria 5-10 part, Semen Vaccariae 10-16 part, Herba Artemisiae Anomalae 5-15 part, Squama Manis 6-15 part,
Caulis Akebiae 5-10 part, Semen Plantaginis 5-10 part, Bi 5-10 part, Cortex Cinnamomi 5-10 part, Herba Cistanches 5-10 part, Radix Rehmanniae Preparata 5-10 part, Folium Pyrrosiae 5-
10 parts, poultry 5-10 part, Fructus Ailanthi 5-10 part, Medulla Junci 5-10 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-
20 parts, Mel, water appropriate.
The medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG the most according to claim 1 treatment prostate hyperplasia, it is characterised in that by
The raw material of following weight portion is made: Radix Codonopsis 8 parts, the Radix Astragali 8 parts, 8 parts of Poria, Semen Vaccariae 12 parts, Herba Artemisiae Anomalae 12 parts, Squama Manis 12
Part, Caulis Akebiae 8 parts, Semen Plantaginis 8 parts, Bi 8 parts, Cortex Cinnamomi 8 parts, Herba Cistanches 8 parts, 8 parts of Radix Rehmanniae Preparata, Folium Pyrrosiae 8 parts, poultry 6 parts, Fructus Ailanthi
6 parts, Medulla Junci 5 parts, 8 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water appropriate.
The medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG the most according to claim 1 treatment prostate hyperplasia, it is characterised in that by
The raw material of following weight portion is made: Radix Codonopsis 5 parts, the Radix Astragali 5 parts, 5 parts of Poria, Semen Vaccariae 10 parts, Herba Artemisiae Anomalae 5 parts, Squama Manis 6 parts,
Caulis Akebiae 5 parts, Semen Plantaginis 5 parts, Bi 5 parts, Cortex Cinnamomi 5 parts, Herba Cistanches 5 parts, 5 parts of Radix Rehmanniae Preparata, Folium Pyrrosiae 5 parts, poultry 5 parts, Fructus Ailanthi 5
Part, Medulla Junci 5 parts, Air Bladder pseudosciaenae seu Acipenser 5, new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Mel, water are appropriate.
The medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG the most according to claim 1 treatment prostate hyperplasia, it is characterised in that by
The raw material of following weight portion is made: Radix Codonopsis 15 parts, the Radix Astragali 12 parts, 10 parts of Poria, Semen Vaccariae 16 parts, Herba Artemisiae Anomalae 15 parts, Squama Manis
15 parts, Caulis Akebiae 10 parts, Semen Plantaginis 10 parts, Bi 10 parts, Cortex Cinnamomi 10 parts, Herba Cistanches 10 parts, 10 parts of Radix Rehmanniae Preparata, Folium Pyrrosiae 10 parts, poultry
10 parts, Fructus Ailanthi 10 parts, Medulla Junci 10 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Mel, water appropriate.
5. the preparation processing method of the medicated tea of clearing away damp-heat warming and recuperating the kidney-YANG treatment prostate hyperplasia, it is characterised in that include with
Lower step；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Medulla Junci cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, each 2 little
Time, merging 2 Medulla Junci ethanol extracts, stand precipitate with ethanol, filter, filtrate is concentrated into without alcohol taste, and is evaporated at 40 DEG C
Relative density is 1.15-1.35, and the extract preparing Medulla Junci is standby；
Bi, Cortex Cinnamomi, Herba Cistanches, Radix Rehmanniae Preparata, Folium Pyrrosiae, poultry, Fructus Ailanthi mix and blend are put into super micron mill, super micron mill
Heating keeps temperature 80 degree 5-6 minute, carries out micronizing and obtains the ultra micro mixing fine powders of 300-400 mesh；Enter relative to ultra micro
Mixing fine powders quality 6～the distilled water of 8 times, first soak 10min～15min, pour in volatile oil extractor, and the way of distillation is extracted and waved
Hair oil 2～4h, it is thus achieved that volatile oil and ultra micro mixing fine powders medicinal residues；
Taking Radix Codonopsis, the Radix Astragali, Poria, Semen Vaccariae, Herba Artemisiae Anomalae, Squama Manis, Caulis Akebiae, Semen Plantaginis, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously adds 30-60 DEG C
After warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, form freezing medicine block, by freezing medicine
Block and ultra micro mixing fine powders medicinal residues boiling are extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carries out
Infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10
Times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, and is concentrated into the 1/2 of original volume, adds Medulla Junci
Extract and volatile oil, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
The preparation processing side of the medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG the most according to claim 5 treatment prostate hyperplasia
Method, it is characterised in that step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C, freezing 5-10 divides
Clock, makes Fructus Vitis viniferae freeze, and after taking out nature defrosting, then carries out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
The preparation processing side of the medicated tea of a kind of clearing away damp-heat warming and recuperating the kidney-YANG the most according to claim 5 treatment prostate hyperplasia
Method, it is characterised in that step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion is 10:0.2～0.8:5～10:0.5.
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| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
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|---|---|---|---|---|
| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
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| Title |
|---|
| 宋芳等: "超临界二氧化碳萃取葡萄籽油及其脂肪酸的分析", 《中国食品工业》 * |
| 李文亮等: "《千家妙方上》", 31 July 1982, 战士出版社 * |
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Application publication date: 20161207 |