CN106109305B - Moisturizing remediation composition containing camellia seed oil and application thereof - Google Patents
Moisturizing remediation composition containing camellia seed oil and application thereof Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61K8/678—Tocopherol, i.e. vitamin E
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Abstract
The present invention provides a kind of moisturizing remediation composition and application thereof containing camellia seed oil, the moisture-keeping composition includes each component of following mass percentage: camellia seed oil 45%~65%, wheat-germ oil 15%~35%, wheat bran extract 5%~10%, bladder-wrack extract 5%~15%, calendula extract 5%~20%, ginger-root extract 5%~10%.The moisture-keeping composition has the advantages that the synergistic effect that effective component can be improved；The chemical moisturizing raw material of organic synthesis is not added, and moisture will not be absorbed inside skin；Easily infiltration, skin easily absorb；Skin barrier can be repaired on the basis of moisturizing, lock moisture from skin inside；Scytitis bring a series of problems can be mitigated.The moisture-keeping composition containing camellia seed oil can be used for preparing cosmetics.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of moisturizing remediation composition containing camellia seed oil and its
Purposes.
Background technique
Moisturizing is always the hot spot in skin care, has dry skin cutaneous appearance, elasticity.The mechanism of dry skin
Very much, it specifically includes that
1) ambient humidity locating for skin is too low to cause transepidermal water loss to increase；
2) it is irradiated with ultraviolet radiation, air pollution and leads to cellular damage using undesirable cosmetics, generate free radical, produce
Raw inflammation, Skin barrier destruction；
3) surfactant makes the sebum film of skin surface lose or dissolve cutin, leads to the natural guarantor between horn cell
The wet factor is lost, and moisture-retention function of skin is destroyed；
Moisturizer at present on the market is main or based on moisturizing, lacks other and repairs barrier, removes free radical, network
Metal ion, it is anti-inflammatory the effects of.
Many moisturizer are mostly chemical moisturizer on the market, need to absorb the moisture ability in air in high humidity environment
Moisturizing, the moisture that can be even absorbed inside skin under conditions of dry cold are more dry by skin.Some are used containing mineral
The skin care item of oil, seem moist, but since its gas permeability is very poor when just beginning to use, will think that skin is more and more thicker at leisure
It is rough and dry, and therefore cutaneous normal excretion program, pore hide many dirts, are stretched, finally result in gradually
The appearance of small pox and dark sore.
Camellia seed oil is highly stable containing unsaturated fatty acids such as vitamin E, linoleic acid, linolenic acid and palmitinic acids
One vegetable oil.Vitamin E has very strong inoxidizability, can remove free radical；Linoleic acid is essential fatty acid, is
The essential component of sebocyte cell；Other unsaturated fatty acids can form film, better moisturizing in skin surface.
Wheat-germ oil, predominantly linoleic acid, oleic acid, palmitinic acid, a small amount of allantoin, arginine, vitamin E.Sub- oil
Acid is essential fatty acid, is played an important role in skin barrier；Allantoin is moisturizer common in a kind of cosmetics.It is small
Wheat germ oil experiment in vitro, which is shown, has proliferation function to epidermal keratinocyte, and 100 μ g/ml are to collagen enzyme inhibition rate
78%, 50 μ g/ml are 12% to DPPH clearance rate, illustrate that wheat-germ oil has the work repaired skin barrier and remove free radical
With.
Wheat bran exchanges section water and oil balance and plays an important role containing a large amount of B family vitamins, meanwhile, Testa Tritici extract is to hydroxyl
Base free radical and superoxide radical have scavenging effect.
Bladder-wrack is a kind of coastal common brown alga, is rich in polysaccharide component, and there are also β-carrotene, zeaxanthin, brown
Algae polyphenol etc..Polysaccharide and brown algae polyphenols contain great amount of hydroxy group with water imbibition, emulsibility and film forming, can be more with other
Saccharic composition and fibrous proteins collectively constitute the extracellular gelatinised matrix containing large quantity of moisture, provide moisture for skin；β-carrot
Element and zeaxanthin remove free radical.Experiment in vitro proves that bladder-wrack extract has inhibiting effect to elastoser, illustrates ink
Angle algae extract plays the role of repairing skin barrier.
Pot marigold, mainly carotenoid compounds, content account for about colored 3%, mainly lutein, luteole,
Lutein ester and β-carrotene, there are also some saponin(es, flavonol glycosides.Saponin(e can promote blood circulation, and guarantee capillary
Nutrition transport；Cell culture shows that pot marigold flower extract plays the role of epidermal cell to promote proliferation；To elastoser
There is inhibiting effect with matrix metalloproteinase, inhibits the decomposition of elastomer and collagen, protection and reparation skin barrier；It is right
The generation of tight junction protein has facilitation, can consolidate the brick wall structure of cuticula；The swelling of rat toes is caused to carrageenan
There is inhibiting effect, illustrates that pot marigold has certain anti-inflammatory effect.
Ginger mainly contains gingerol, and the aliphatic chain connected according to functional group is different, is broadly divided into gingerol class, zingiberone class, ginger
Glycols.Ginger extract has spectrum antimicrobial properties；It is stronger to DPPH and superoxide radical Scavenging activity in vitro；To prostaglandin E2
Inhibiting effect is stronger, there is stronger anti-inflammatory effect.
Summary of the invention
In view of the drawbacks of the prior art, the object of the present invention is to provide a kind of moisturizing remediation composition containing camellia seed oil
And application thereof.The present invention repairs (including ultraviolet light, air pollution, micro- by cellular damage from the mechanism of a variety of dry skins
Caused by biology) free radical that generates, inflammation and lead to skin barrier problem, while moisturizing and water conservation pass through selection moisturizing group
It closes and matches, solve the problems, such as that moisturizing ingredient is single and trade-off effect is not good enough, make skin wet, keep elasticity and the degree of packing.
The purpose of the present invention is what is be achieved through the following technical solutions:
In a first aspect, the present invention provides a kind of moisturizing remediation composition containing camellia seed oil, including following quality hundred
Divide each component of content:
Preferably, the moisturizing remediation composition containing camellia seed oil includes each group of following mass percentage
Point:
Second aspect, use of the moisturizing remediation composition in cosmetics containing camellia seed oil that the present invention provides a kind of
On the way.
The third aspect, the present invention provides a kind of moisture surge treatment formula, each components including following mass percentage: aforementioned
The moisturizing remediation composition 20% containing camellia seed oil, glycerol 6%, 1,2- pentanediol 2%, EDETATE SODIUM 0.1%, PEG-
100 stearates 1.5%, stearine 0.5%, Cholesteryl hydroxystearate 1.0%, cetanol 2%, docosyl alcohol
0.5%, dimethyl silicone polymer 1.0%, cholesterine 0.2%, xanthan gum 0.3%, butanediol 3%, Phenoxyethanol 0.5%, right
Hydroxy acetophenone 0.5%, Sodium Hyaluronate 0.05%, essence 0.1%, surplus are water.
Fourth aspect, the present invention provides a kind of preparation methods of moisture surge treatment formula, comprising the following steps: A1, weighs respectively
Water phase components water, glycerol, 1,2- pentanediol, EDETATE SODIUM are sequentially added kettle by component, are heated to 85-95 DEG C, stirring is equal
It is even, mixing speed 15-25rpm；
A2, by oil phase component PEG-100 stearate, stearine, Cholesteryl hydroxystearate, cetanol,
Docosyl alcohol, dimethyl silicone polymer, cholesterine sequentially add oil cauldron, are heated to 80-85 DEG C, stir evenly, mixing speed 15-
25rpm；
A3, oil phase component is mixed with water phase components, and the mixed liquor of xanthan gum and butanediol is added, then homogeneous is protected
Temperature；
A4, the mixed solution for sequentially adding Phenoxyethanol and parahydroxyacet-ophenone, Sodium Hyaluronate aqueous solution and perfume (or spice)
Essence, after mixing evenly, discharging.
Preferably, in step A3, the homogenizing time is 5 minutes, and homogeneous speed is 3000rpm；The holding temperature is
80-85 DEG C, soaking time is 30 minutes.
Preferably, in step A4, at 50 DEG C, the aqueous solution and essence of the hyaluronic acid is added.
5th aspect, the present invention provides a kind of skin-moisturizing, skin oil, each components including following mass percentage: aforementioned
The moisturizing remediation composition 70% containing camellia seed oil, parahydroxyacet-ophenone 0.3%, 1,2- hexylene glycol 0.2%, Ku Suola reed
Luxuriant growth liquid extract 1%, hydrogenation Sweet Almond Oil 1%, the auspicious palmitic acid fruit oil 1% of hair, tocopherol acetate 1%, Queensland nut seed oil 1%,
Wild soybean oil 1%, avocado oil 2%, jojoba seed oil 2%, bisabolol 0.5%, german chamomile flower extract 1%, sweet orange blossom oil
0.2%, pentaerythritol tetra (di-tert-butyl hydroxy hydrocinnamate) 0.3%, surplus are ethylhexyl palmitate.
6th aspect, the present invention provides a kind of preparation methods of skin-moisturizing, skin oil, comprising the following steps:
B1, ethylhexyl palmitate, parahydroxyacet-ophenone, 1,2- hexylene glycol are sequentially added in pot, heating stirring is to complete
Fully dissolved；
B2, by Ku Suola aloe liquid extract, hydrogenation Sweet Almond Oil, the auspicious palmitic acid fruit oil of hair, tocopherol acetate, Queensland nut
Seed oil, Wild soybean oil, avocado oil, jojoba seed oil, bisabolol, german chamomile flower extract, sweet orange blossom oil, pentaerythrite four (it is double-
Tert-butyl hydroxy hydrocinnamic acid) ester sequentially adds in pot, stirs evenly；
B3, it stirs evenly, discharges after adding the moisturizing remediation composition containing camellia seed oil in pot.
Preferably, the speed of the stirring is 15-25rpm.
Compared with prior art, the present invention have it is following the utility model has the advantages that
1, the synergistic effect of effective component is improved；
2, the chemical moisturizing raw material (such as glycine betaine, urea, polyethylene glycol) of organic synthesis is not added, it will not be inside skin
Absorb moisture；
3, easily infiltration, skin easily absorb；
4, skin barrier can be repaired on the basis of moisturizing, lock moisture from skin inside；
5, scytitis bring a series of problems can be mitigated.
Specific embodiment
The present invention is described in detail combined with specific embodiments below.Following embodiment will be helpful to the technology of this field
Personnel further understand the present invention, but the invention is not limited in any way.It should be pointed out that the ordinary skill of this field
For personnel, without departing from the inventive concept of the premise, various modifications and improvements can be made.These belong to the present invention
Protection scope.
Each component raw material involved in following embodiment and comparative example is the commercially available universal product, related experimental method
It is method commonly used in the art.
Examples 1 to 3
The present embodiment 1-3 provides a kind of moisture-keeping composition and moisture surge treatment formula containing camellia seed oil, shown moisturizing group
Component and the weight proportion for closing object are as shown in table 1.
Table 1
Moisture surge treatment formula described in the present embodiment 1-3 includes each component of following mass percentage: containing camellia seed oil
Moisturizing remediation composition 20%, glycerol 6%, 1,2- pentanediol 2%, EDETATE SODIUM 0.1%, PEG-100 stearate
1.5%, stearine 0.5%, Cholesteryl hydroxystearate 1.0%, cetanol 2%, docosyl alcohol 0.5%, poly- diformazan
Radical siloxane 1.0%, cholesterine 0.2%, xanthan gum 0.3%, butanediol 3%, Phenoxyethanol 0.5%, parahydroxyacet-ophenone
0.5%, Sodium Hyaluronate 0.05%, essence 0.1%, surplus are water.
The preparation method of the moisture surge treatment formula the following steps are included:
A1, each component is weighed, water phase components water, glycerol, 1,2- pentanediol, EDETATE SODIUM is sequentially added into kettle, heated
It to 85-95 DEG C, stirs evenly, mixing speed 15-25rpm；
A2, by oil phase component PEG-100 stearate, stearine, Cholesteryl hydroxystearate, cetanol,
Docosyl alcohol, dimethyl silicone polymer, cholesterine sequentially add oil cauldron, are heated to 80-85 DEG C, stir evenly, mixing speed 15-
25rpm；
A3, oil phase component is mixed with water phase components, and the mixed liquor of xanthan gum and butanediol is added, then homogeneous is protected
Temperature；
Sequentially added after A4, cooling the mixed solution of Phenoxyethanol and parahydroxyacet-ophenone, Sodium Hyaluronate it is water-soluble
Liquid and essence, after mixing evenly, discharging.
In step A3, the homogenizing time is 5 minutes, and homogeneous speed is 3000rpm；The holding temperature is 80-85 DEG C,
Soaking time is 30 minutes.
In step A4, at 50 DEG C, the aqueous solution and essence of the hyaluronic acid is added.
Comparative example 1~7
This comparative example 1-7 provides a kind of moisture-keeping composition and moisture surge treatment formula containing camellia seed oil, shown moisturizing group
Component and the weight proportion for closing object are as shown in table 1.
Table 2
The preparation method of moisture surge treatment formula described in this comparative example 1-7 is same as Example 1.
Compliance test result
1, human body moistening effect is tested
Method: it is divided into the measurement of short-acting moisturizing measurement and long-acting moisturizing.30 health dry skin volunteers participate in
This experiment, men and women is unlimited, and the age between 18-65 years old, did not participated in any drug, cosmetics or health care in nearest three months
The clinical trial of product.
1.1 short-acting moisturizings
8 regions of Instrument measuring, left and right shank mark are identified in subject's left and right arm with ready template in advance
Know 6 regions of Instrument measuring out, size is 4*2.5cm2；
The blank district for removing left and right arm uses sample in all test sections, and sample usage amount is 2mg/cm2；
Skin is first eluted with water before basic value test, is measured again after skin is dry after 30min；Sample uses later
1h afterwards, 2h, 4h, 6h, 8h are measured；
This test equipment is Corneometer (CK), for measuring the moisture content of skin；It is first used before test every time
Water clearing skin is measured again after skin is dry after 30min；
At 22 ± 2 DEG C, relative humidity is 50 ± 5% for laboratory ambient temperature control.
1.2 long-acting moisturizings
8 regions of Instrument measuring, size 4* are identified in subject's left and right arm with ready template in advance
2.5cm2；
The blank district of removing left and right arm is marked in all test sections with skin marking pen, is respectively used once sooner or later,
30d sample is used continuously, sample usage amount is 2mg/cm2；
Other any skin care item or drug cannot be used in 30d
This test equipment is Corneometer (CK), for measuring the moisture content of skin；Testing time point is sample
Before use, the 1w after sample use, 2w, 3w, 4w；Skin is first eluted with water before test every time, after skin is dry after 30min again
It is measured (at 22 ± 2 DEG C, relative humidity is 50 ± 5% for laboratory ambient temperature control), original life is kept during experiment
Rule.
Moisture surge treatment formula prepared by embodiment 1-3 and comparative example 1-7 carries out moistening effect verifying, experimental result such as table
3 and table 4 shown in.
The short-acting moisturizing test result of table 3.
The long-acting moisturizing test result of table 4.
2, skin barrier function is tested
30 health dry skin volunteers participate in this experiment (being same personnel with above two groups of experiments), men and women
Unlimited, the age between 18-65 years old, did not participated in any drug, the clinical trial of cosmetics or health care product in nearest three months.
Various inherent and external factor all can cutaneous permeability barrier, cuticula is the product of epidermis terminal differentiation,
It can prevent the evaporation of moisture.TEWL (percutaneous loss of moist) reflection is evaporation capacity of the water from skin surface, is evaluation skin
The important indicator of barrier function.
TEWL (percutaneous loss of moist) test method:
8 regions of Instrument measuring, size 4* are identified in subject's left and right arm with ready template in advance
2.5cm2；
The blank district of removing left and right arm is marked in all test sections with skin marking pen, is respectively used once sooner or later,
30d sample is used continuously, sample usage amount is 2mg/cm2；
Other any skin care item or drug cannot be used in 30d；
This test equipment is Corneometer (CK), for measuring TEWL (percutaneous loss of moist)；Testing time point is
Sample is before use, 1w, 4w after sample use；Skin is first eluted with water before test every time, after skin is dry after 30min again into
Row measurement (at 22 ± 2 DEG C, relative humidity is 50 ± 5% for laboratory ambient temperature control)；
Original rule of life is kept during experiment.
Moisture surge treatment formula prepared by embodiment 1-3 and comparative example 1-7 carries out skin barrier function test, experimental result
As shown in table 5.
Table 5.TEWL test result
Interpretation of result: by table 3,4,5 as it can be seen that this programme is obvious to dry skin effect, the rapid moisturizing of energy, and adhere to making
With the water content that can improve skin, skin barrier is repaired, reduces moisture loss.
Embodiment 4
A kind of skin-moisturizing, skin oil is present embodiments provided, each component including following mass percentage: prepared by embodiment 1
The moisturizing remediation composition 70% containing camellia seed oil, parahydroxyacet-ophenone 0.3%, 1,2- hexylene glycol 0.2%, Ku Suola reed
Luxuriant growth liquid extract 1%, hydrogenation Sweet Almond Oil 1%, the auspicious palmitic acid fruit oil 1% of hair, tocopherol acetate 1%, Queensland nut seed oil 1%,
Wild soybean oil 1%, avocado oil 2%, jojoba seed oil 2%, bisabolol 0.5%, german chamomile flower extract 1%, sweet orange blossom oil
0.2%, pentaerythritol tetra (di-tert-butyl hydroxy hydrocinnamate) 0.3%, surplus are ethylhexyl palmitate.
The preparation method of the oil of skin-moisturizing, skin described in the present embodiment, comprising the following steps:
B1, ethylhexyl palmitate, parahydroxyacet-ophenone, 1,2- hexylene glycol are sequentially added in pot, heating stirring is to complete
Fully dissolved；
B2, by Ku Suola aloe liquid extract, hydrogenation Sweet Almond Oil, the auspicious palmitic acid fruit oil of hair, tocopherol acetate, Queensland nut
Seed oil, Wild soybean oil, avocado oil, jojoba seed oil, bisabolol, german chamomile flower extract, sweet orange blossom oil, pentaerythrite four (it is double-
Tert-butyl hydroxy hydrocinnamic acid) ester sequentially adds in pot, stirs evenly；
B3, it stirs evenly, discharges after adding the moisturizing remediation composition containing camellia seed oil in pot.
The speed of the stirring is 15-25rpm.
There are many concrete application approach of the present invention, the above is only a preferred embodiment of the present invention.More than it should be pointed out that
Embodiment is merely to illustrate the present invention, and the protection scope being not intended to restrict the invention.For the common skill of the art
For art personnel, without departing from the principle of the present invention, several improvement can also be made, these improvement also should be regarded as this hair
Bright protection scope.
Claims (6)
1. a kind of moisturizing remediation composition containing camellia seed oil, which is characterized in that by each component of following mass percentage
Composition:
2. a kind of purposes of the moisturizing remediation composition in cosmetics containing camellia seed oil as described in claim 1.
3. a kind of moisture surge treatment formula, which is characterized in that be grouped as by each group of following mass percentage: such as claims 1 or 2
The moisturizing remediation composition 20% containing camellia seed oil, glycerol 6%, 1,2- pentanediol 2%, EDETATE SODIUM 0.1%,
PEG-100 stearate 1.5%, stearine 0.5%, Cholesteryl hydroxystearate 1.0%, cetanol 2%, behenyl
Alcohol 0.5%, dimethyl silicone polymer 1.0%, cholesterine 0.2%, xanthan gum 0.3%, butanediol 3%, Phenoxyethanol 0.5%,
Parahydroxyacet-ophenone 0.5%, Sodium Hyaluronate 0.05%, essence 0.1%, surplus are water.
4. a kind of preparation method of moisture surge treatment formula as claimed in claim 3, which comprises the following steps:
A1, each component is weighed, water phase components water, glycerol, 1,2- pentanediol, EDETATE SODIUM is sequentially added into kettle, are heated to 85-
It 95 DEG C, stirs evenly, mixing speed 15-25rpm；
A2, by oil phase component PEG-100 stearate, stearine, Cholesteryl hydroxystearate, cetanol, behenyl
Alcohol, dimethyl silicone polymer, cholesterine sequentially add oil cauldron, are heated to 80-85 DEG C, stir evenly, mixing speed 15-25rpm；
A3, oil phase component is mixed with water phase components, and the mixed liquor of xanthan gum and butanediol is added, then homogeneous is kept the temperature；
A4, the mixed solution for sequentially adding Phenoxyethanol and parahydroxyacet-ophenone, Sodium Hyaluronate aqueous solution and essence, stir
After mixing uniformly, discharging.
5. the preparation method of moisture surge treatment formula as claimed in claim 4, which is characterized in that in step A3, the homogenizing time
It is 5 minutes, homogeneous speed is 3000rpm；The holding temperature is 80-85 DEG C, and soaking time is 30 minutes.
6. the preparation method of moisture surge treatment formula as claimed in claim 4, which is characterized in that in step A4, at 50 DEG C, institute is added
State the aqueous solution and essence of Sodium Hyaluronate.
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