CN107929131A - Anti-apolexis composition and application thereof - Google Patents
Anti-apolexis composition and application thereof Download PDFInfo
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- CN107929131A CN107929131A CN201711295810.4A CN201711295810A CN107929131A CN 107929131 A CN107929131 A CN 107929131A CN 201711295810 A CN201711295810 A CN 201711295810A CN 107929131 A CN107929131 A CN 107929131A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The present invention relates to a kind of anti-apolexis composition, including following components in percentage by weight：First 1.5 parts of active component~2.5 parts；Second 0.5 part of active component~2 parts；First active component is common milfoil extract, and second active component is Punica granatum L. extract and the mixture of Sodium Ascorbyl Phosphate.Above-mentioned composition has effects that anti-aging, moisturizing, whitening, careful pore, alleviation are sensitive.
Description
Technical field
The present invention relates to daily necessities technical field, more particularly to anti-apolexis composition and application thereof.
Background technology
Aging be body respectively organize, organ dysfunction with advancing age and occur degeneration change, have many factors
Body aging can be induced.How the aging of body is delayed, particularly the aging of skin, in daily necessities technical field into grinding
The heat topic studied carefully.But some the anti-aging daily necessities that presently, there are, there are single effect or it is ineffective, be also easy to produce accordance with tolerance and
Easily cause the side effects such as body allergy.
The content of the invention
Based on this, it is necessary to for how delay skin aging the problem of, there is provided a kind of anti-apolexis composition and application thereof.
A kind of anti-apolexis composition, includes the component of following parts by weight：
First 1.5 parts of active component~2.5 parts；
Second 0.5 part of active component~2 parts；
First active component is common milfoil extract, and second active component is Punica granatum L. extract and ascorbic acid
The mixture of sodium phosphate.
Above-mentioned anti-apolexis composition is using common milfoil extract as the first active component, Punica granatum L. extract and ascorbic acid phosphorus
The mixture of acid esters sodium is as the second active component, and two kinds of active component compoundings form, due to the synergistic effect of each component so that
Said composition has more preferable anti-aging effects.
The presence of excessive free radical in vivo can cause the excessive crosslinking of collagen, and collagenous fibres reconfigure to be formed surely
Fixed cellulose, its elasticity significantly reduce, and accelerate the formation of wrinkle of skin, and contain more polyphenol thing in Punica granatum L. extract
Matter, it can reduce the generation of body oxygen radical, so as to play the role of anti-aging.In addition, Punica granatum L. extract can also press down
The activity of Collagenase processed and elastoser, reduces the decomposition of collagen.Sodium Ascorbyl Phosphate is also a kind of anti-
Oxidant, it can suppress the reaction with oxygen, so as to avoid aoxidizing and become sour.And Punica granatum L. extract and ascorbic acid phosphoric acid esters
Sodium can suppress the expression of matrix metalloproteinase (MMP-1) while the synthesis of collagen is promoted in mRNA level in-site, from
And reduce the decomposition of collagen.Common milfoil extract reduces skin senescence by promoting cell-cell communication.And first is active
Component and the second active component mix in certain proportion, its action effect is substantially better than a kind of independent active component.It is probably
Since common milfoil extract by promoting cell-cell communication promotes the effect of the polyphenol substance in Punica granatum L. extract etc..
In addition, there is stronger hydrophily there are great amount of hydroxy group in polyphenol substance in Punica granatum L. extract, can also with it is more
Sugar, polyalcohol, lipid, protein and polypeptide etc. form the stronger compound of moisture retention.Also containing transparent in Punica granatum L. extract
Matter acid, hyaluronic acid can absorb the moisture of even thousands of times of sole mass hundreds of.Therefore it is stronger to have above-mentioned composition
Moisture-keeping efficacy.
Common milfoil extract also has effects that to alleviate skin sensitivity, therefore above-mentioned composition is not only applicable in common skin,
The symptoms such as redness, the itch of sensitive skin can also be alleviated, be applicable in wider.
In addition, acid ascorbyl ester sodium has careful pore, whitening effect.
Above-mentioned composition has effects that anti-aging, moisturizing, whitening, careful pore, alleviation are sensitive, i.e., above-mentioned composition can
While the effect of to keep each component each, the effect of can also mutually strengthening each component.
In a wherein embodiment, the part by weight of first active component and second active component is 1：1~
2.5：1.
Application of the above-mentioned anti-apolexis composition in skin care item.
The effect of due to above-mentioned composition anti-aging, moisturizing, whitening, careful pore, sensitive alleviation, it is properly applied to skin care
In product, corresponding water, breast, frost etc. can be made according to the selection of auxiliary material.
A kind of anti-aging skin care product, including above-mentioned anti-apolexis composition.
Above-mentioned anti-aging skin care product, including solvent and following components in percentage by weight：
Above-mentioned anti-apolexis composition 2%~4.5%；
In a wherein embodiment, the thickener is selected from：Maltodextrin, xanthans, carbomer, Sodium Polyacrylate, chlorine
Change homopolymer, acrylic copolymer, nutrition wire-drawing protein matter sodium, the high molecular cellulose of trimethylammoniumethyl methacrylate
In one or more；
The moisturizer is selected from：Glycerine, 1,3-BDO, 1,3-PD, 1,2- pentanediols, glycerol caprylate, sorb
Alcohol, polyethylene glycol, glycine betaine, hyaluronic acid, ceramide, collagen, urea, chitin derivativ, aloe and seaweed
One or more in extract；
The emollient is selected from：Saualane, avocado stearyl oleate, polyethylene glycol laurate, polyethylene glycol oleic acid
One or more in ester；
The antioxidant is selected from：Tocopherol acetate, vitamin C, polyphenol green-tea extract, Olive leaf P.E, jasmine
One or more in jasmine flower extract；
The neutralizer is triethanolamine；The preservative is decoyl hydroximic acid.
A kind of anti-ageing face mask, is made of the component of following weight ratio：
A phases：Xanthans 0.05%~0.12%, carbomer 0.15%~0.2%, glycine betaine 2.0%~3.1%；
B phases：Triethanolamine 0.1%~0.3%；
C phases：Saualane 2.5%~3.5%, tocopherol acetate 0.5%~1.8%；
D phases：1,3-PD 0.1%~0.6%, decoyl hydroximic acid 0.1~1.0%, glycerol caprylate 0.2%~
0.6%；
E phases：Anti-apolexis composition 2%~4.5%, 1,3-BDO 0.1%~0.6% described in claim 1 or 2,
1,2- pentanediol 0.1%~0.6%, maltodextrin 0.05%~0.3%；
Surplus is water.
The anti-ageing face mask of said components composition has preferable anti-aging, moisturizing, white-skinned face function, pungent additionally by adding
Acyl hydroximic acid and glycerol caprylate composition mixture, can not have to add other preservatives and effectively prevent product by microorganism
Pollution, product milder, is applicable in sensitivity flesh.
In a wherein embodiment, the anti-ageing face mask is made of the component of following weight ratio：
A phases：Xanthans 0.05%~0.12%, carbomer 0.15%~0.2%, glycine betaine 2.0%~3.1%；
B phases：Triethanolamine 0.1%~0.3%；
C phases：Saualane 2.5%~3.5%, tocopherol acetate 0.5%~1.8%；
D phases：1,3-PD 0.1%~0.6%, decoyl hydroximic acid 0.1~1.0%, glycerol caprylate 0.2%~
0.6%；
E phases：Anti-apolexis composition 2%~3.5%, 1,3-BDO 0.2%~0.5% described in claim 1 or 2,
1,2- pentanediol 0.2%~0.5%, maltodextrin 0.1%~0.3%；
Surplus is water.
In a wherein embodiment, the anti-ageing face mask is made of the component of following weight ratio：
A phases：Xanthans 0.1%, carbomer 0.18%, glycine betaine 3%；
B phases：Triethanolamine 0.2%；
C phases：Saualane 3%, tocopherol acetate 1%；
D phases：1,3-PD 0.1%, decoyl hydroximic acid 0.8%, glycerol caprylate 0.5%；
E phases：Anti-apolexis composition 3%, 1,3-BDO 0.2%, 1,2- pentanediols described in claim 1 or 2
0.2%th, maltodextrin 0.1%；
Surplus is water.
A kind of anti-ageing face mask, includes the upper anti-apolexis composition.
Since above-mentioned composition has effects that anti-aging, moisturizing, whitening, careful pore, alleviation are sensitive, suitably it is made anti-
Aging facial mask.
A kind of method for preparing preceding claim anti-ageing face mask, comprises the following steps：
The A is added in water, the heating stirring stipulated time at 60 DEG C -80 DEG C, adds the B phases, continue to stir
Mix the stipulated time；Then C phases are added, carry out homogeneous, after keeping the temperature the stipulated time, 42 DEG C -50 DEG C is cooled to, adds D phases, Ran Houji
It is continuous to be cooled to 30 DEG C -40 DEG C, E phases are added, are stirred evenly.
Required anti-ageing face mask can be made while the activity of active component is kept in this method.
Embodiment
It should be noted that extract refers to a kind of be dissolved in solvent and being obtained by soaking or mixing the material extracted
The solution obtained.Extraction process can carry out with the help of suitable solvent is selected, such as：Water, ethanol, ethanol/water mixture, first
Alcohol, propyl alcohol, butanol, chloroform, acetone or other organic solvents, and by isolating, decocting, it is counter-current extraction, ultrasonic wave, microwave, super
The method of critical flow extraction, which obtains extract extract, to be further concentrated by evaporation, and obtain medicinal extract and dried object.
Punica granatum L. extract：It is the thing extracted using the one or more in the root of pomegranate, stem, leaf, flower, fruit as raw material
Matter, is preferably extracted from pomegranate flower, rich in abundant Punica granatum L. polyphenol, polysaccharide, polyalcohol, lipid, protein, polypeptide, hyalomitome
The materials such as acid.
Common milfoil extract：Using the root of common milfoil, stem, leaf, spend in the material that is extracted as raw material of one or more.
Contain the materials such as alpine yarrow element, α-camphor, aconitic acid, butadiene, amber glass acid, linoleic acid, a variety of amino acid, flavonoids, sesquiterpenoids.
In addition, mixture of second active component for Punica granatum L. extract and Sodium Ascorbyl Phosphate, the ratio of the two without
It is particularly limited to, Punica granatum L. extract：The ratio of acid ascorbyl ester sodium can be 1：5~5：1.
In addition, each the selection of auxiliary material (thickener, moisturizer, neutralizer, emollient, antioxidant, preservative) can be with
Made choice according to the needs of preparation, and the auxiliary material is cosmetic field acceptable auxiliary material.According to the selection of auxiliary material, the group
Water, breast, frost, elite, eye cream, facial mask etc. can be made in compound.A set of product can also be made, the product include water, breast, frost,
Elite, eye cream, facial mask.
Said composition can also be mixed with other active materials, as long as not damaging the effect of said composition.
With reference to specific embodiment, the present invention will be described.
It should be noted that the reagent or instrument in specific source is not specified in the present invention, for market purchase conventional reagent or
Instrument.
Embodiment one
According to the form below 1,2 compositions formulated of table
Table 1
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 | |
| First active component | 1% | 2% | 1.5% | 1% | 4% | 3.75% |
| Second active component | 0.5% | 1% | 1.5% | 2% | 2% | 1.5% |
Table 2
| Comparative example 1 | Comparative example 2 | Comparative example 3 | Comparative example 4 | Comparative example 5 | |
| First active component | 2% | 0 | 4% | 0 | 0 |
| Second active component | 0 | 1% | 0 | 2% | 0 |
Above-described embodiment 1- embodiments 5, the auxiliary material of comparative example 1- comparative examples 5 are：Xanthans 0.1%, carbomer
0.18%th, glycine betaine 3%, triethanolamine 0.2%, saualane 3%, tocopherol acetate 1%, 1,3-PD 0.1%, decoyl
Hydroximic acid 0.8%, glycerol caprylate 0.5%, 1,3-BDO 0.1%, 1,2- pentanediols 0.1%, maltodextrin 0.1%；It is remaining
Measure as water.
Above-described embodiment 1- embodiments 5,5 preparation method of comparative example 1- comparative examples：
Xanthans, carbomer, glycine betaine are added to the water, heating stirring 10min, adds triethanolamine at 70 DEG C,
Continue to stir 10min；Then saualane, tocopherol acetate are added, (3000 revs/min) progress homogeneous of high speed homogenization is opened, protects
After warm 5min, 45 DEG C are cooled to, 1,3-PD, decoyl hydroximic acid, glycerol caprylate is added, then proceedes to be cooled to 40 DEG C,
The first active component and/or the second active component (comparative example 5 is not added with active component) are added by table 1, is stirred evenly, 38 DEG C go out
Material.
Embodiment two
(1) expression of test matrix metalloproteinases -1 (MMP-1)
By young fibroblast (the present embodiment is selected from the cell of 32 years old adult female) and aging adult fiber finer
Born of the same parents' (the present embodiment is selected from the cell of 64 years old adult female) are inoculated into 48 porocyte culture plates respectively, and each hole is contained
0.75*105A cell, and the starvation 24h in serum free medium.Starved cells are rinsed with PBS, and use treatment with ultraviolet light.So
The test sample shown in Tables 1 and 2 is added in 48h afterwards.Used after 72h in MMP-1 kits culture mediums and separate MMP-1
Expression.Using blank control (comparative example 6) senescent fibroblast as MMP-1 expression 100%, measure other samples to be tested
(embodiment 1- embodiments 6, comparative example 1- comparative examples 5) is relative to the MMP-1 expression quantity of the comparative example 6.
(embodiment 1- embodiments 6, the concentration of comparative example 1- comparative examples 5 are 5 μ L to test result such as table 3, comparative example 6 is empty
White control, that is, be not added with sample)
Compared to comparative example 6, embodiment 1- embodiments 6 and comparative example 1- comparative examples 4 all have MMP-1 inhibitory action,
Since comparative example 5 is free of active component, substantially without effect, it can release, the first active component and/or the second active component can be with
Suppress MMP-1 expression.
In addition, embodiment 1 and embodiment 2 contain the first active component and the second active component, comparative example 1 is only contains the
One active component, the concentration of the first active component is identical with the concentration of the first active component in comparative example 1 in embodiment 2, from table 3
As can be seen that embodiment 1 is better than comparative example 1 to the inhibition of MMP-1.In addition, the percentage of the first active component of embodiment 1
Content is less than the content of the first active component of comparative example 1, from table 3 it can be seen that embodiment 1 is excellent to the inhibition of MMP-1
In comparative example 1.
Comparative example 2 contains only the second active component, and the concentration of second active component is lived with comparative example 2 second in embodiment 2
The concentration of property component is identical, from table 3 it can be seen that embodiment 2 is better than comparative example 2 to the inhibition of MMP-1.In addition, implement
The percentage composition of second active component of example 1 is less than the content of the second active component of comparative example 2, from table 3 it can be seen that implementing
Example 1 is better than comparative example 2 to the inhibition of MMP-1.
In addition, contrast comparative example 1 and comparative example 2 are as can be seen that comparative example 2 is better than comparative example to the inhibition of MMP-1
1。
In conclusion predominantly the second active component of inhibitory action is played to MMP-1, and the first active component can be strengthened
There is synergistic effect in the effect of the second active component, i.e. the first active component and the second active component.Even if increase active component
Concentration (comparative example 3 and comparative example 4), its effect is still not as the immixture of the first active component and the second active component
(embodiment 1, embodiment 2).
In addition, from embodiment 1- embodiments 5 as can be seen that the optimal proportion of the first active component and the second active component is
2：1, and increase the concentration (embodiment 5) of active component, to the humidification and unobvious of the inhibition of MMP-1.And to year
Light fibroblast and senescent fibroblast all have effect, are better than aging into fibre to young fibroblastic action effect
Tie up cell.
(2) detection of soluble collagen secretion is promoted
Human fibroblasts will be cultivated in the DMEM culture mediums containing 10%FBS, and be seeded on 48 orifice plates, cell attachment
Afterwards, culture medium exchange is carried out with the DMEM culture mediums containing 0.25%FBS and magnesium ascorbyl phosphate, added in Tables 1 and 2
Sample.After cultivating 72h, medium supernatant is recycled, is centrifuged, soluble collagen contains in measure gained supernatant
Amount.As a result such as table 4.
(embodiment 1- embodiments 6, the concentration of comparative example 1- comparative examples 5 are 10 μ L to table 4, comparative example 6 is blank control, i.e.,
It is not added with sample)
From table 4, it can be seen that the percentage composition of the soluble collagen of embodiment 1- embodiments 6 is higher than 1- pairs of comparative example
Ratio 4, comparative example 5 without effect, illustrate the effect of the promotion collagen synthesis of the composition containing two kinds of active components substantially
Better than a kind of component, and auxiliary material is substantially without the effect for promoting collagen synthesis.And the concentration of increase active component is conducive to glue
The synthesis of former albumen, but act on unobvious.
In addition, comparative example 1 and comparative example 1, comparative example 2 are as can be seen that 1 active component concentration of embodiment is less than contrast
Example 1, but effect is better than comparative example 1, illustrates that the first active component and the second active component have synergistic effect.
(3) allergic reaction is tested
It is real that embodiment 1- is carried out to tester 30 (- 30 years old 20 years old 10 people, -40 years old 31 years old 10 people, -50 years old 41 years old 10 people)
Apply the patch test of example 6.As a result such as table 6
Table 5 is skin adverse reaction grade scale
6 patch test results of table
Test group all has no adverse reaction, and can carry out follow-up test.
(4) measure of whitening and moistening effect
Mask product is made in the component of embodiment 2, is used to 30 testers through patch test, weekly using 1-2
It is secondary, tested and given a mark within every 1 month, 3 months.Standards of grading are as follows：
Wrinkle degree：No wrinkle 10 divides, substantially wrinkle-free line 7-9 divides, more 4-6 points of wrinkle, many 1-3 points of wrinkle；
Skin elasticity：Fine 10 points, good 7-9 points, general 4-6 points, 1-3 points of difference；
Skin water humidity：Fine 10 points, good 7-9 points, general 4-6 points, 1-3 points of difference；
Skin tightness：Fine 10 points, good 7-9 points, general 4-6 points, 1-3 points of difference；
Whitening skin degree：Fine 10 points, good 7-9 points, general 4-6 points, 1-3 points of difference；
Colour of skin lightness：Fine 10 points, good 7-9 points, general 4-6 points, 1-3 points of difference；
Resultant effect：Fine 10 points, good 7-9 points, general 4-6 points, 1-3 points of difference；
Instrument：Cutometer Cutometer MPA 580, moisture of skin measuring instrument, dermal melanin and blood red
Plain measuring instrument, face-image analysis system；
Measured according to the specification of instrument, (wherein, the first row of each effect represents statistical result such as table 7- tables 9
Using the scoring before product, the second row represents the scoring after using 1 month, and the third line represents the scoring after using 3 months).
Table 7
Table 8
Table 9
From table 7- tables 9 as can be seen that the facial mask that is prepared by embodiment 2 has anti-aging, whitening, moisturizing, highlights skin
Color etc. acts on.And from table 8 and table 9 as can be seen that all have effect to the people of 31-50 Sui, the anti-wrinkle effect of -40 years old 31 years old compared with
To be obvious, the people for being particularly suitable for the age bracket uses.
(5) accordance with tolerance is tested
Tester is used continuously 6 months in above-mentioned (4), stops using the product, does not occur the phenomenon of discomfort, and not
Appearance skin returns to the phenomenon using the state before product, judges no accordance with tolerance.
Each technical characteristic of embodiment described above can be combined arbitrarily, to make description succinct, not to above-mentioned reality
Apply all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, the scope that this specification is recorded all is considered to be.
Embodiment described above only expresses the several embodiments of the present invention, its description is more specific and detailed, but simultaneously
Cannot therefore it be construed as limiting the scope of the patent.It should be pointed out that come for those of ordinary skill in the art
Say, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention
Scope.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (10)
1. a kind of anti-apolexis composition, it is characterised in that include the component of following parts by weight：
First 1.5 parts of active component~2.5 parts；
Second 0.5 part of active component~2 parts；
First active component is common milfoil extract, and second active component is Punica granatum L. extract and ascorbic acid phosphoric acid
The mixture of ester sodium.
2. anti-apolexis composition according to claim 1, it is characterised in that first active component and described second is lived
Property component part by weight be 1：1~2.5：1.
3. application of the anti-apolexis composition described in claim 1 or 2 in skin care item.
4. a kind of anti-aging skin care product, it is characterised in that including the anti-apolexis composition described in claim 1 or 2.
5. anti-aging skin care product according to claim 4, it is characterised in that the group including solvent and following percentage by weight
Point：
6. anti-aging skin care product according to claim 5, it is characterised in that the thickener is selected from：Maltodextrin, xanthan
Glue, carbomer, Sodium Polyacrylate, the homopolymer of chlorination trimethylammoniumethyl methacrylate, acrylic copolymer, nutrition are drawn
One or more in silk protein sodium, high molecular cellulose；
The moisturizer is selected from：It is glycerine, 1,3-BDO, 1,3-PD, 1,2- pentanediols, glycerol caprylate, sorbierite, poly-
Ethylene glycol, glycine betaine, hyaluronic acid, ceramide, collagen, urea, chitin derivativ, aloe and marine algae extract
In one or more；
The emollient is selected from：In saualane, avocado stearyl oleate, polyethylene glycol laurate, polyethylene glycol (PEG) oleate
One or more；
The antioxidant is selected from：Tocopherol acetate, vitamin C, polyphenol green-tea extract, Olive leaf P.E, Jasmine
One or more in extract；
The neutralizer is triethanolamine；The preservative is decoyl hydroximic acid.
7. a kind of anti-ageing face mask, it is characterised in that the anti-ageing face mask is made of the component of following weight ratio：
A phases：Xanthans 0.05%~0.12%, carbomer 0.15%~0.2%, glycine betaine 2.0%~3.1%；
B phases：Triethanolamine 0.1%~0.3%；
C phases：Saualane 2.5%~3.5%, tocopherol acetate 0.5%~1.8%；
D phases：1,3-PD 0.1%~0.6%, decoyl hydroximic acid 0.1%~1.0%, glycerol caprylate 0.2%~0.6%；
E phases：Anti-apolexis composition 2%~4.5%, 1,3-BDO 0.1%~0.6%, 1,2- described in claim 1 or 2
Pentanediol 0.1%~0.6%, maltodextrin 0.05%~0.3%；
Surplus is water.
8. anti-ageing face mask according to claim 7, it is characterised in that the anti-ageing face mask by following weight ratio group
It is grouped into：
A phases：Xanthans 0.05%~0.12%, carbomer 0.15%~0.2%, glycine betaine 2.0%~3.1%；
B phases：Triethanolamine 0.1%~0.3%；
C phases：Saualane 2.5%~3.5%, tocopherol acetate 0.5%~1.8%；
D phases：1,3-PD 0.1%~0.6%, decoyl hydroximic acid 0.1~1.0%, glycerol caprylate 0.2%~0.6%；
E phases：Anti-apolexis composition 2%~3.5%, 1,3-BDO 0.2%~0.5%, 1,2- described in claim 1 or 2
Pentanediol 0.2%~0.5%, maltodextrin 0.1%~0.3%；
Surplus is water.
9. anti-ageing face mask according to claim 8, it is characterised in that the anti-ageing face mask by following weight ratio group
It is grouped into：
A phases：Xanthans 0.1%, carbomer 0.18%, glycine betaine 3%；
B phases：Triethanolamine 0.2%；
C phases：Saualane 3%, tocopherol acetate 1%；
D phases：1,3-PD 0.1%, decoyl hydroximic acid 0.8%, glycerol caprylate 0.5%；
E phases：Anti-apolexis composition 3%, 1,3-BDO 0.2% described in claim 1 or 2,1,2- pentanediols 0.2%, wheat
Bud dextrin 0.1%；
Surplus is water.
A kind of 10. method for preparing claim 7-9 any one of them anti-ageing face masks, it is characterised in that including following step
Suddenly：
The A is added in water, the heating stirring stipulated time at 60 DEG C -80 DEG C, adds the B phases, continues stirring rule
Fix time；Then C phases are added, carry out homogeneous, after keeping the temperature the stipulated time, 42 DEG C -50 DEG C is cooled to, adds D phases, then proceed to drop
Temperature adds E phases, stirs evenly to 30 DEG C -40 DEG C.
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| CN109316368A (en) * | 2018-11-28 | 2019-02-12 | 韩艳辉 | Anti-aging skin care product and preparation method thereof |
| CN109875938A (en) * | 2019-01-30 | 2019-06-14 | 陕西崇文生物科技有限公司 | It is a kind of to improve the colour of skin and antianaphylactic reparation liquid and preparation method thereof |
| CN113476374A (en) * | 2021-08-12 | 2021-10-08 | 广州锦同生物科技有限公司 | Anti-wrinkle cosmetic and preparation method thereof |
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| CN113476374A (en) * | 2021-08-12 | 2021-10-08 | 广州锦同生物科技有限公司 | Anti-wrinkle cosmetic and preparation method thereof |
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| CN107929131B (en) | 2020-11-10 |
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