CN109316368A - Anti-aging skin care product and preparation method thereof - Google Patents
Anti-aging skin care product and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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Abstract
The present invention relates to a kind of anti-aging skin care products and preparation method thereof, wherein, by weight percentage, anti-aging skin care product includes: the MossCellTec of 60%~93% water, 5%~20% moisturizer, 0.1%~0.5% thickener, 0.01%~0.1% chelating agent, 0.01%~0.3% emollient, the RoyalEpigen P5 of 0.1%~1% meter Bai Le company of Switzerland production and the production of 0.2%~5% meter Bai Le company of SwitzerlandTMNo.1.The anti-aging skin care product has the characteristics that spreadability is good, it is splendid to be easy to absorption, moisturizing effect and anti-aging effects by each component collocation, synergistic function.
Description
Technical field
The present invention relates to cosmetic fields, more particularly to a kind of anti-aging skin care product and preparation method thereof.
Background technique
Aging is the inexorable law of life growth, wherein the variation with skin is the most obvious, the skin after aging have with
Lower feature: wrinkle increases, Dermatochalasia, and gloss, smoothness, tension and elasticity reduce, and dermatoglyph is thicker, and pigmentation increases
Deng, and these are all beautiful formidable enemies.With the raising of people's consumption consciousness and concept of health, people are intended to that " youth is forever
In ", therefore the various methods for preventing aging are found by every possible means, anti-aging cosmetics become the majority of consumers' urgent need
One of product.
Currently, the generally accepted aging free radical theory of people is thought, the degeneration variation in aging course is due to thin
Caused by the illeffects of the free radical generated in born of the same parents' normal metabolic processes.Since free radical increases in skin, damage biological film,
Promote the skins such as elastic protein fiber increase and amorphization and collagen fabric substantially reduce and grape ammonia glycan increases
Aging phenomenon.Therefore, anti-aging cosmetics mainly pass through the ingredient that addition has antioxidation at present, such as Victoria C, dimension E, tomato
Red pigment, ursolic acid, resveratrol etc. prevent the damaging action of free radical to realize confrontation and remove excessive free radicals, or pass through
Moisturizing delays senescence with skin barrier function or replenishing collagen and elastin laminin etc. is repaired.
However, such anti-aging cosmetics there are anti-senescence functions it is relatively single, anti-aging effects are unobvious the defects of, because
This, needs to develop a kind of apparent multifunctional antisenescence product of anti-aging effects.
Summary of the invention
Based on this, it is necessary to provide a kind of preferable anti-aging skin care product of anti-aging effects.
A kind of anti-aging skin care product, by weight percentage, comprising: 60%~93% water, 5%~20% moisturizer,
0.1%~0.5% thickener, 0.01%~0.1% chelating agent, 0.01%~0.3% emollient, 0.1%~1% Switzerland rice hundred
The RoyalEpigen P5 of the happy company's production and MossCellTec of 0.2%~5% meter Bai Le company of Switzerland productionTMNo.1。
Studies have shown that nucleus is close with Senescence, in senile cell, under passing in and out the transport capacity of nucleus significantly
Drop, and cell laten to the adaptability of environmental change it is slow.The above-mentioned anti-aging skin care product of the present invention is each in vital movement from improving
The haulage level of kind of substance disengaging nucleus and the angle of cytothesis is promoted to set out, by RoyalEpigen P5 and
MossCellTecTMNo.1 cooperates moisturizer, emollient, thickener, chelating agent etc. to use, and regulates matching for each raw material component
Than obtaining that spreadability is good, be easy to absorb, that moisturizing effect and anti-aging effects are splendid is anti-by each component synergistic function
Aging skin care item.
The MossCellTec of meter Bai Le company of Switzerland productionTMNo.1 is using small liwan moss (Physcomitrella
What protonema culture patens) was produced, include mainly phytol, different malt and water, nucleus can be improved
The carrying capacity of nuclear Pore Complex promotes cell kernel function.The RoyalEpigen P5 of meter Bai Le company of Switzerland production is by water
The biochemically active composition that the wooden fruit rouge of solution royal jelly albumen, hydrolecithin, glycerol, cream, maltodextrin and water are formed by combining, water
Solution royal jelly albumen can degrade aging protein, accelerate regeneration, smooth skin, and the wooden fruit rouge of cream, hydrolecithin and
The absorption that glycerol can increase percutaneous permeability, reinforce horn cell.Above-mentioned anti-aging skin care product utilizes
MossCellTecTMNo.1 improves the carrying capacity of molecule disengaging nucleus in senile cell to promote cell kernel function, makes cell
Restore young state, so that offsetting various metabolism in aging course slows down brought influence, while passing through RoyalEpigen
P5 gives front active influence, degradation aging protein and quickening skin renewal, the product to the epigenetic substance of gene
It is able to ascend cell kernel function, elasticity of skin is maintained, promotes cell senescence protein degradation and Skin Cell regeneration, smooth skin,
Delay skin aging from many aspects has significant anti-aging effects.
In one of the embodiments, by weight percentage, comprising: 80%~90% water, 5%~10% moisturizer,
0.2%~0.5% thickener, 0.03%~0.8% chelating agent, 0.1%~0.3% emollient, 0.3%~0.8% Switzerland rice
The RoyalEpigen P5 of the hundred happy company's productions and MossCellTec of 1%~3% meter Bai Le company of Switzerland productionTMNo.1。
The moisturizer is selected from butanediol, 1,3-PD, Sodium Hyaluronate, hyalomitome in one of the embodiments,
The Pellicer that acid, sodium lactate, two (lauramide glutamine) Sodium lysinates and Japanese Chemical Group of Asahi Chemical Industry produce
At least one of LB-10.
The moisturizer is butanediol, 1,3-PD, Sodium Hyaluronate and two (laurels in one of the embodiments,
Amide Gln) Sodium lysinate.
Two (lauramide glutamine) Sodium lysinates are double head type amphoteric amino acids surfactant, have common chloro
The superiority that acid is unable to reach, two amino acid moiety form twin-lock structure with peptide bond, have duplex structure and multiple acyls
Amine key, it is especially good to skin affinity, be conducive to the barrier function for improving skin；And its structure energy for being similar to ceramide
Enough high-effective penetratings help the ceramide in cellular matrix to be restored to the level of healthy skin, such as intensity, thickness to keratoderma
Degree, elasticity and water-retaining property.The present invention can significantly improve the moistening effect of product by being used cooperatively above-mentioned a variety of moisturizer
While can also improve anti-aging effects.
The moisturizer is butanediol, 1,3-PD, Sodium Hyaluronate and the Japanese rising sun in one of the embodiments,
The Pellicer LB-10 produced at Chemical Group.
The Pellicer LB-10 of Japanese Chemical Group of Asahi Chemical Industry production mainly includes butanediol, two (lauramides
Glutamine) Sodium lysinate and water, wherein two (lauramide glutamine) Sodium lysinates come from plant extracts.
The emollient is selected from isopropyl palmitate, olive oil, myristic acid isopropyl in one of the embodiments,
At least one of ester, Trivent OCG, Triglyceride DDD, Parleam and glycerol three (thylhexoic acid) ester.
The thickener is selected from hydroxyethyl cellulose, hydroxypropyl methyl cellulose, card wave in one of the embodiments,
At least one of nurse, xanthan gum and polyacrylic acid.
The chelating agent is selected from disodium ethylene diamine tetraacetate (EDETATE SODIUM) and citric acid in one of the embodiments,
At least one.
The anti-aging skin care product further includes 0.5wt%~1.5wt% preservative in one of the embodiments,.
The preservative is Phenoxyethanol and parahydroxyacet-ophenone in one of the embodiments,.
Further, in the anti-aging skin care product, the weight ratio of the parahydroxyacet-ophenone and the Phenoxyethanol
For (1~1.2): 1.
Parahydroxyacet-ophenone is naturally present in compositae plant and Asclepiadaceae plant, has anti-oxidant, anti-irritant and wide spectrum
Anti-corrosion ability, and have preferable water-soluble, it is possible to reduce addition preservative bring irritation.Phenoxyethanol has low cause
Quick, broad-spectrum high efficacy antisepsis and sterilization ability, and water can be dissolved in but also be dissolved in oil, it is easy to use.Make above by the two compounding
With can play synergy antisepsis, reduce the usage amount of single preservative, reduce stimulation.
The anti-aging skin care product further includes 0.03wt%~0.3wt% anti-sensitizer in one of the embodiments,.
In one of the embodiments, the anti-sensitizer in dipotassium glycyrrhizinate, bisabolol and allantoin at least
It is a kind of.
The anti-sensitizer is dipotassium glycyrrhizinate in one of the embodiments,.
Dipotassium glycyrrhizinate has anti-inflammatory, antiallergy, moisturizing and other effects.The antiallergic that so can not only get up effect, moreover it is possible to rise
To certain fire-resistance and moistening effect.
In one of the embodiments, by weight percentage, comprising: 85%~90% water, 3%~6% butanediol,
2%~4%1,3-propanediol, 0.02%~0.1%EDTA disodium, 0.2%~0.4% hydroxyethyl cellulose, 0.05%~
0.2% Sodium Hyaluronate, 0.1%~0.3% xanthan gum, 0.3%~0.8% meter Bai Le company of Switzerland produce
RoyalEpigen P5, Pellicer LB-10 of 0.3%~0.8% Japanese Chemical Group of Asahi Chemical Industry production, 1%~
The MossCellTec of 3% meter Bai Le company of Switzerland productionTMNo.1,0.1%~0.3% dipotassium glycyrrhizinate, 0.3%~0.5% benzene
Oxyethanol and 0.2%~0.7% parahydroxyacet-ophenone.
Another object of the present invention is to provide a kind of preparation method of above-mentioned anti-aging skin care product, include the following steps:
According to the formula of the anti-aging skin care product, each component is mixed, is stirred evenly, the antisenility skin care is obtained
Product.
Described the step of mixing each component, is as follows in one of the embodiments:
The hydroxyethyl cellulose, the Sodium Hyaluronate, the xanthan gum are added sequentially in the butanediol, stirred
It mixes uniformly, obtains mixture A；
Under agitation, the 1,3-PD, the EDETATE SODIUM and the water are uniformly mixed, obtain mixture B；
After mixing by the mixture A and the mixture B, rear to cool down in 65 DEG C~80 DEG C 5~15min of heat preservation
To 40 DEG C~48 DEG C, RoyalEpigen P5, the Pellicer LB-10 and the MossCellTec is addedTMNo.1,
It stirs evenly, obtains mixture C；
The dipotassium glycyrrhizinate, the Phenoxyethanol, the parahydroxyacet-ophenone and the mixture C are mixed, stirring
Uniformly, the anti-aging skin care product is obtained.
Above-mentioned preparation method simple process is controllable, and obtained good product consistency facilitates popularization.
Specific embodiment
To facilitate the understanding of the present invention, below will to invention is more fully described, and give it is of the invention compared with
Good embodiment.But the invention can be realized in many different forms, however it is not limited to embodiment described herein.Phase
Instead, purpose of providing these embodiments is makes the disclosure of the present invention more thorough and comprehensive.
Unless otherwise defined, all technical and scientific terms used herein and belong to technical field of the invention
The normally understood meaning of technical staff is identical.Term as used herein in the specification of the present invention is intended merely to description tool
The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term as used herein "and/or" includes one or more phases
Any and all combinations of the listed item of pass.
Raw material used in the specific embodiment of the invention derives from commercially available.
One, anti-aging skin care product and preparation method thereof
Examples 1 to 5 and 1~3 anti-aging skin care product raw material shown in the following table 1 of comparative example are made:
1~3 each group distribution ratio (weight percent) of 1 Examples 1 to 5 of table and comparative example
Note: "-" expression is not added.
The step of preparation method of the anti-aging skin care product of Examples 1 to 5 and comparative example 1~3, is as follows:
1), hydroxyethyl cellulose, Sodium Hyaluronate, xanthan gum are added sequentially in butanediol, stirred evenly, is mixed
Close object A.
2), deionized water is added in emulsion pot, opens stirring, mixing speed is set as 60 revs/min, and 1,3- the third two is added
Alcohol, EDETATE SODIUM mix, obtain mixture B.
3), into mixture B be added mixture A, continue stirring be mixed after, be heated to 73 DEG C~78 DEG C, and keep the temperature
10 minutes, until all materials are completely dispersed.
4) when, being cooled to 45 DEG C, RoyalEpigen P5, Pellicer LB-10 (or two (lauramide glutamy is added
Amine) Sodium lysinate) and MossCellTecTMNo.1 is stirred evenly, and obtains mixture C.
5) it, sequentially adds dipotassium glycyrrhizinate, Phenoxyethanol, parahydroxyacet-ophenone into mixture C, stirs 20 minutes, directly
To being completely dispersed.
6) when, being cooled to 35 DEG C~40 DEG C, filtering and discharging, gained filtrate is anti-aging skin care product.
Two, each performance test
1, delay senescence test (testing in vitro)
Test sample: Examples 1 to 5 and comparative example 1~3
Test method:
1), cause the fibroblast aging of human normal with hydrogen peroxide.
2), then the embodiment and comparative example sample containing 1.5% is cultivated respectively.
3), they are carried out with the activity analysis of beta galactosidase, this enzyme can accumulate in the cell of aging, therefore it
It is the biological marker of an aging.It is identified by histochemistal staining technique, and shoots and calculate dyeing under the microscope carefully
The quantity of born of the same parents.
Experimental result:
1), after dioxygen water process, the fibroblast quantity of aging increases three times.
2), after sample culturing, the quantity of staining cell is reduced, wherein after the sample culturing containing embodiment 3
Staining cell quantity reduces 55%, and embodiment 2 reduces 47%, and embodiment 4 reduces 49%, and embodiment 1 and embodiment 5 are divided
Do not reduce 35% and 38%, comparative example 1 reduces 15%, and comparative example 2 reduces 12%, and comparative example 3 reduces 8%.
3), the result shows that:
1) sample containing Examples 1 to 5, which carries out culture poststaining cell quantity, reduces 35% or more, illustrates the present invention
Anti-aging skin care product has definite effect in terms of preventing cell senescence.
2) comparative example 1~3 can prevent cell senescence to a certain extent, but effect is unobvious, and the embodiment of the present invention 1~
5 are preventing the cell senescence from having remarkable result compared with comparative example 1~3, illustrate in anti-aging skin care product of the invention, RoyalEpigen
P5 and MossCellTecTMNo.1 has synergistic effect, can significantly prevent cell senescence according to the addition of certain dosage, and obvious good
In exclusive use RoyalEpigen P5 or MossCellTecTMNo.1。
2, product safety assessment (human skin patch test result)
Evaluation method:
1) tested material: the sample of Examples 1 to 5
2) negative control: deionized water
3) subject: totally 30 people, male 10 people, 20 people of female the age 18~40 years old, meet subject and volunteer inclusion criteria.
4) spot test method: selecting qualified spot tester, with enclosed patch test method, by tested material about 0.02ml~
0.025ml is applied in spot tester, and external application special adhesive tape is pasted on subject's forearm song side, removes tested material after 24 hours, in going
Except 30min after tested material spot tester, dermoreaction is observed after impression disappearance, by " cosmetics health specification " (version in 2007)
Dermoreaction grade scale records its result.
5) evaluation of result: reaction result is recorded by table 3 (skin adverse reaction grading standard).
6) 4 test result: be see the table below
4 human skin patch test result of table
Human skin patch test result is shown:
In Examples 1 to 5,30 subjects skins are all negative (grading system: 0 grade).According to " cosmetics are defended
Raw specification " (version in 2007) human skin class patch test judgment criteria, sample is to human body without skin adverse reaction.
Experiment conclusion: the mildness of the anti-ageing skin care item of the above embodiment of the present invention 1~5 is very high, is completely suitable for each
The crowd of class skin quality.
3, normal individual trial is evaluated
Sample: Examples 1 to 5 and comparative example 1~3.
Trier: 30~40 years old female volunteers, totally 100 people.
Test method: before using sample, trier cleans face using identical mild face cleaning product, and left face smears this
The anti-aging skin care product of inventive embodiments, right face smear the product of equivalent comparative example, and frequency of use is once in the morning and once at night, continuously often
It is used, and the trial period is 60 days, and when use avoids outdoor from being exposed to the sun.Evaluation table on probation is filled according to sensory evaluation, primary evaluation refers to
Indicate: spreadability, moisturizing effect, improves skin elasticity and reduces deep wrinkles effect absorbability, and highest is divided into 5 points, minimum
It 1 point, is finally counted and is compared.
Evaluation result on probation see the table below 5:
Table 5
From the feedback result on probation of upper table 5 it is found that the anti-aging skin care product spreadability of the above embodiment of the present invention 1~5 it is good,
It easily absorbs, moisturizing effect is good, can significantly improve the elasticity of skin, it is obvious to reduce deep wrinkles effect, and compared to comparative example 1
~3 significant effect.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (10)
1. a kind of anti-aging skin care product, which is characterized in that by weight percentage, comprising: 60%~93% water, 5%~20%
Moisturizer, 0.1%~0.5% thickener, 0.01%~0.1% chelating agent, 0.01%~0.3% emollient, 0.1%~1%
What the RoyalEpigen P5 of meter Bai Le company of Switzerland production and 0.2%~5% meter Bai Le company of Switzerland produced
MossCellTecTMNo.1。
2. anti-aging skin care product according to claim 1, which is characterized in that by weight percentage, comprising: 80%~
90% water, 5%~10% moisturizer, 0.2%~0.5% thickener, 0.03%~0.8% chelating agent, 0.1%~0.3% profit
Skin agent, the RoyalEpigen P5 of 0.3%~0.8% meter Bai Le company of Switzerland production and 1%~3% meter Bai Le company of Switzerland are raw
The MossCellTec of productionTMNo.1。
3. anti-aging skin care product according to claim 1, which is characterized in that the moisturizer is selected from butanediol, 1,3- third
Glycol, Sodium Hyaluronate, hyaluronic acid, sodium lactate, two (lauramide glutamine) Sodium lysinates and Japanese Asahi Chemical Industry's chemistry
At least one of the Pellicer LB-10 of group company's production.
4. anti-aging skin care product according to claim 1, which is characterized in that the emollient be selected from isopropyl palmitate,
Olive oil, isopropyl myristate, Trivent OCG, three (ethyl of Triglyceride DDD, Parleam and glycerol
Caproic acid) ester at least one.
5. anti-aging skin care product according to claim 1, which is characterized in that the thickener be selected from hydroxyethyl cellulose,
At least one of hydroxypropyl methyl cellulose, carbomer, xanthan gum and polyacrylic acid.
6. described in any item anti-aging skin care products according to claim 1~5, which is characterized in that the anti-aging skin care product is also
Including 0.5wt%~1.5wt% preservative.
7. anti-aging skin care product according to claim 6, which is characterized in that the preservative is for Phenoxyethanol and to hydroxyl
Acetophenone.
8. described in any item anti-aging skin care products according to claim 1~5, which is characterized in that the anti-aging skin care product is also
Including 0.03wt%~0.3wt% anti-sensitizer.
9. anti-aging skin care product according to claim 1, which is characterized in that by weight percentage, comprising: 85%~
90% water, 3%~6% butanediol, 2%~4%1,3-propanediol, 0.02%~0.1%EDTA disodium, 0.2%~0.4% hydroxyl
Ethyl cellulose, 0.05%~0.2% Sodium Hyaluronate, 0.1%~0.3% xanthan gum, 0.3%~0.8% Switzerland rice hundred are happy
The Pellicer LB- that RoyalEpigen P5 of company's production, 0.3%~0.8% Japanese Chemical Group of Asahi Chemical Industry produce
10, the MossCellTec of 1%~3% meter Bai Le company of Switzerland productionTMNo.1,0.1%~0.3% dipotassium glycyrrhizinate, 0.3%
~0.5% Phenoxyethanol and 0.2%~0.7% parahydroxyacet-ophenone.
10. the preparation method of any one of claim 1~9 anti-aging skin care product, which comprises the following steps:
According to the formula of the anti-aging skin care product, each component is mixed, is stirred evenly, the anti-aging skin care product is obtained.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110420150A (en) * | 2019-09-16 | 2019-11-08 | 深圳市悦青春健康科技有限公司 | A kind of anti-aging skin care product composition containing Moringa seed extract |
| CN110613648A (en) * | 2019-10-22 | 2019-12-27 | 花安堂生物科技集团有限公司 | Skin care composition capable of improving skin barrier and application thereof |
| CN111012721A (en) * | 2019-12-23 | 2020-04-17 | 广州市拉凯尔干细胞研究所 | Skin care composition for improving skin brightness |
| CN111035583A (en) * | 2019-12-23 | 2020-04-21 | 广州市拉凯尔干细胞研究所 | Skin care product composition for improving true epidermis junction layer |
| CN114948771A (en) * | 2022-03-17 | 2022-08-30 | 广东丸美生物技术股份有限公司 | Composition containing tetrahydrocurcumin, preparation method thereof and skin care product |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002293731A (en) * | 2001-03-23 | 2002-10-09 | L'oreal Sa | Composition containing fiber for resisting to ageing of skin |
| GB201101733D0 (en) * | 2010-02-03 | 2011-03-16 | Lvmh Rech | Cosmetic composition |
| KR20160148174A (en) * | 2015-06-16 | 2016-12-26 | 주식회사 아미코스메틱 | Cosmetic composition containing propolis complex extracts |
| CN107929131A (en) * | 2017-12-08 | 2018-04-20 | 广州智媛生物科技有限公司 | Anti-apolexis composition and application thereof |
| CN108175720A (en) * | 2018-03-06 | 2018-06-19 | 宁夏医科大学 | A kind of skin care item |
| CN108379110A (en) * | 2018-05-16 | 2018-08-10 | 广州莎利曼尔生物科技有限公司 | Skin care compositions, skin care cream and preparation method thereof |
| CN108514519A (en) * | 2018-05-11 | 2018-09-11 | 珠海伊斯佳科技股份有限公司 | A kind of skin care compositions and methods and its application method of whitening and anti-aging |
-
2018
- 2018-11-28 CN CN201811434435.1A patent/CN109316368B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002293731A (en) * | 2001-03-23 | 2002-10-09 | L'oreal Sa | Composition containing fiber for resisting to ageing of skin |
| GB201101733D0 (en) * | 2010-02-03 | 2011-03-16 | Lvmh Rech | Cosmetic composition |
| KR20160148174A (en) * | 2015-06-16 | 2016-12-26 | 주식회사 아미코스메틱 | Cosmetic composition containing propolis complex extracts |
| CN107929131A (en) * | 2017-12-08 | 2018-04-20 | 广州智媛生物科技有限公司 | Anti-apolexis composition and application thereof |
| CN108175720A (en) * | 2018-03-06 | 2018-06-19 | 宁夏医科大学 | A kind of skin care item |
| CN108514519A (en) * | 2018-05-11 | 2018-09-11 | 珠海伊斯佳科技股份有限公司 | A kind of skin care compositions and methods and its application method of whitening and anti-aging |
| CN108379110A (en) * | 2018-05-16 | 2018-08-10 | 广州莎利曼尔生物科技有限公司 | Skin care compositions, skin care cream and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| DSWISS德瑞丝: ""关于RoyalEpigen P5你需要知道这些"", 《HTTPS://WWW.SOHU.COM/A/232465302_491998》 * |
| PERSONAL CARE: ""improving skin resilience with MossCellTecTMNo.1"", 《PERSONAL CARE MAGAZINE》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110420150A (en) * | 2019-09-16 | 2019-11-08 | 深圳市悦青春健康科技有限公司 | A kind of anti-aging skin care product composition containing Moringa seed extract |
| CN110613648A (en) * | 2019-10-22 | 2019-12-27 | 花安堂生物科技集团有限公司 | Skin care composition capable of improving skin barrier and application thereof |
| JP2021066731A (en) * | 2019-10-22 | 2021-04-30 | 花安堂生物科技集団有限公司 | Skin care composition that improves skin barrier function, manufacturing method of skin care composition, and skin care products |
| CN111012721A (en) * | 2019-12-23 | 2020-04-17 | 广州市拉凯尔干细胞研究所 | Skin care composition for improving skin brightness |
| CN111035583A (en) * | 2019-12-23 | 2020-04-21 | 广州市拉凯尔干细胞研究所 | Skin care product composition for improving true epidermis junction layer |
| CN114948771A (en) * | 2022-03-17 | 2022-08-30 | 广东丸美生物技术股份有限公司 | Composition containing tetrahydrocurcumin, preparation method thereof and skin care product |
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