CN106109305A - Moisturizing remediation composition containing Camellia oil and application thereof - Google Patents
Moisturizing remediation composition containing Camellia oil and application thereof Download PDFInfo
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- CN106109305A CN106109305A CN201610571771.5A CN201610571771A CN106109305A CN 106109305 A CN106109305 A CN 106109305A CN 201610571771 A CN201610571771 A CN 201610571771A CN 106109305 A CN106109305 A CN 106109305A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
Abstract
The invention provides a kind of moisturizing remediation composition containing Camellia oil and application thereof, described moisture-keeping composition includes each component of following weight/mass percentage composition: Camellia oil 45%～65%, Semen Tritici aestivi germ oil 15%～35%, Testa Tritici extract 5%～10%, Fucus Vesiculosus extract 5%～15%, Flos Inulae extract 5%～20%, ginger-root extract 5%～10%.Described moisture-keeping composition has the advantages that the synergism that can improve effective ingredient；Without the chemical moisturizing raw material of organic synthesis, moisture will not be absorbed inside skin；Easily infiltration, skin easily absorbs；Skin barrier can be repaired, from skin internal pinning moisture on the basis of moisturizing；The series of problems that scytitis brings can be alleviated.The described moisture-keeping composition containing Camellia oil can be used for preparing cosmetics.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to a kind of moisturizing remediation composition containing Camellia oil and
Purposes.
Background technology
Moisturizing is always the focus in skin nursing, the cutaneous outward appearance of xerosis cutis, elasticity.Xerodermatic mechanism
A lot, specifically include that
1) ambient humidity residing for skin is too low causes transepidermal water loss to increase；
2) be irradiated with, air pollution and the bad cosmetics of use cause cell injury, generate free radical, produce
Raw inflammation, Skin barrier destruction；
3) surfactant makes the sebum film loss of skin surface or dissolves cutin, causes the natural guarantor between horn cell
The wet factor runs off, and moisture-retention function of skin is destroyed；
Moisturizer the most on the market is main still based on moisturizing, lacks other and repairs barriers, removes free radical, network
Metal ion, antiinflammatory etc. act on.
A lot of wetting agents mostly are chemistry wetting agent on the market, need to absorb the moisture ability in air in high humidity environment
Moisturizing, even can absorb the moisture inside skin drier by skin under conditions of dry cold.Some uses containing mineral
The skin care item of oil, seem when just beginning to use moist, but due to its breathability extreme difference, will think that skin is more and more thicker at leisure
Rough and dry, and cutaneous normal excretion program, therefore pore is hidden a lot of dirt, is gradually stretched, finally results in
Small pox and the appearance of skin sore.
Camellia oil, containing unsaturated fatty acids such as vitamin E, linoleic acid, linolenic acid and Palmic acids, is highly stable
One vegetable oil.Vitamin E has the strongest non-oxidizability, can remove free radical；Linoleic acid is essential fatty acid, is
The essential component of sebocyte cell；Other unsaturated fatty acid can form film, more preferable moisturizing at skin surface.
Semen Tritici aestivi germ oil, predominantly linoleic acid, oleic acid, Palmic acid, a small amount of allantoin, arginine, vitamin E.Sub-oil
Acid is essential fatty acid, plays an important role in skin barrier；Allantoin is wetting agent common in a kind of cosmetics.Little
Wheat germ oil experiment in vitro shows proliferation function to epidermal keratinocyte, and collagen protein enzyme inhibition rate is by 100 μ g/ml
78%, 50 μ g/ml are 12% to DPPH clearance rate, illustrate that Semen Tritici aestivi germ oil has and repair skin barrier and remove the work of free radical
With.
Testa Tritici, containing a large amount of vitamin B group, exchanges joint water and oil balance and plays an important role, and meanwhile, Testa Tritici extract is to hydroxyl
Base free radical and superoxide radical have scavenging action.
Fucus Vesiculosus, is coastal common a kind of Brown algae, rich in polysaccharide component, also bata-carotene, cryptoxanthin, Brown algae
Polyphenol etc..Polysaccharide and brown algae polyphenols contain great amount of hydroxy group and are allowed to have water absorption, emulsibility and film property, it is also possible to other polysaccharide
Component and fibrous proteins collectively constitute the outer gelatinised matrix of the born of the same parents containing large quantity of moisture, provide moisture for skin；Beta-carotene and
Cryptoxanthin removes free radical.Experiment in vitro proves that Fucus Vesiculosus extract has inhibitory action to elastoser, and Fucus Vesiculosus is described
Extract has the effect repairing skin barrier.
Flos Inulae, mainly carotenoid compounds, content accounts for the 3% of flower, mainly phylloxanthin, zeaxanthin, leaf
Flavin ester and bata-carotene, also have some saponin, flavonol glycosides.Saponin can be with blood circulation promoting, it is ensured that blood capillary
Nutrition is transported；Cell cultivates display Flos Inulae flower extract the effect promoting propagation to epidermis cell；To elastoser and
Matrix metalloproteinase has inhibitory action, suppression elastic fiber and the decomposition of collagen protein, protects and repairs skin barrier；To tightly
The generation of close connection albumen has facilitation, can consolidate cuticular brick wall structure；Carrageenin is caused rat toes swelling have
Inhibitory action, illustrates that Flos Inulae has certain antiinflammatory action.
Rhizoma Zingiberis Recens, mainly containing gingerol, different according to the aliphatic chain that functional group is connected, it is broadly divided into gingerol class, zingiberone class, Rhizoma Zingiberis Recens
Glycols.Rhizoma Zingiberis Recens extract has spectrum antibacterial；External stronger to DPPH and superoxide radical Scavenging activity；To PGE2
Inhibitory action is relatively strong, has stronger antiinflammatory action.
Summary of the invention
For the defect of prior art, it is an object of the invention to provide a kind of moisturizing remediation composition containing Camellia oil
And application thereof.The mechanism that the present invention is dried from various skin, repairs and (is included ultraviolet, air pollution, micro-by cell injury
Biology causes) free radical of generation, inflammation and cause skin barrier problem, moisturizing simultaneously and water conservation, by select moisturizing group
Close and proportioning, solve the problem that moisturizing ingredient is single and trade-off effect is not good enough, make skin wet, keep the elastic and degree of packing.
It is an object of the invention to be achieved through the following technical solutions:
First aspect, the invention provides a kind of moisturizing remediation composition containing Camellia oil, including following quality hundred
Each component of point content:
Preferably, the described moisturizing remediation composition containing Camellia oil includes each group of following weight/mass percentage composition
Point:
Second aspect, the invention provides a kind of moisturizing remediation composition containing Camellia oil use in cosmetics
On the way.
The third aspect, the invention provides a kind of moisture surge treatment formula, including each component of following weight/mass percentage composition: aforementioned
The moisturizing remediation composition 20% containing Camellia oil, glycerol 6%, 1,2-pentanediol 2%, EDETATE SODIUM 0.1%, PEG-
100 stearates 1.5%, glyceryl stearate 0.5%, Cholesteryl hydroxystearate 1.0%, spermol 2%, behenyl alcohol
0.5%, polydimethylsiloxane 1.0%, cholesterol 0.2%, xanthan gum 0.3%, butanediol 3%, phenoxyethanol 0.5%, right
Hydroxy acetophenone 0.5%, hyaluronate sodium 0.05%, essence 0.1%, surplus are water.
Fourth aspect, the invention provides the preparation method of a kind of moisture surge treatment formula, comprises the following steps: A1, weigh each
Component, by water phase components water, glycerol, 1,2-pentanediol, EDETATE SODIUM are sequentially added into kettle, are heated to 85-95 DEG C, and stirring is all
Even, mixing speed 15-25rpm；
A2, by oil phase component PEG-100 stearate, glyceryl stearate, Cholesteryl hydroxystearate, spermol,
Behenyl alcohol, polydimethylsiloxane, cholesterol are sequentially added into oil cauldron, are heated to 80-85 DEG C, stir, mixing speed 15-
25rpm；
A3, oil phase component is mixed with water phase components, and add the mixed liquor of xanthan gum and butanediol, homogenizing, then protect
Temperature；
A4, sequentially add phenoxyethanol and the mixed solution of parahydroxyacet-ophenone, the aqueous solution of hyaluronate sodium and perfume (or spice)
Essence, after stirring, discharging.
Preferably, in step A3, described homogenizing time is 5 minutes, and homogenizing speed is 3000rpm；Described holding temperature is
80-85 DEG C, temperature retention time is 30 minutes.
Preferably, in step A4, when 50 DEG C, add described hyalomitome aqueous acid and essence.
5th aspect, the invention provides a kind of skin-moisturizing, skin oil, including each component of following weight/mass percentage composition: aforementioned
The moisturizing remediation composition 70% containing Camellia oil, parahydroxyacet-ophenone 0.3%, 1,2-hexanediol 0.2%, Ku Suola reed
Luxuriant growth liquid extract 1%, hydrogenation Semen pruni armeniacae oil 1%, hair auspicious palmitic acid fruit oil 1%, tocopherol acetas 1%, macadimia nut seed oil 1%,
Wild soybean oil 1%, American Avocado Tree oil 2%, Jojoba seed oil 2%, bisabolol 0.5%, Flos Chrysanthemi extract 1%, sweet orange blossom oil
0.2%, pentaerythritol tetra (di-tert-butyl hydroxy hydrocinnamate) 0.3%, surplus are ethylhexyl palmitate.
6th aspect, the invention provides the preparation method of a kind of skin-moisturizing, skin oil, comprises the following steps:
B1, by ethylhexyl palmitate, parahydroxyacet-ophenone, 1,2-hexanediol is sequentially added in pot, and heated and stirred is to the completeest
CL；
B2, by Ku Suola aloe liquid extract, hydrogenation Semen pruni armeniacae oil, hair auspicious palmitic acid fruit oil, tocopherol acetas, macadimia nut
Seed oil, Wild soybean oil, American Avocado Tree oil, Jojoba seed oil, bisabolol, Flos Chrysanthemi extract, sweet orange blossom oil, tetramethylolmethane four (double-
Tert-butyl hydroxy hydrocinnamic acid) ester is sequentially added in pot, stirs；
B3, the moisturizing remediation composition containing Camellia oil is added after in pot and stir, discharging.
Preferably, the speed of described stirring is 15-25rpm.
Compared with prior art, the present invention has a following beneficial effect:
1, the synergism of effective ingredient is improved；
2, without the chemical moisturizing raw material (such as glycine betaine, carbamide, Polyethylene Glycol) of organic synthesis, will not be inside skin
Absorb moisture；
3, easily permeating, skin easily absorbs；
4, skin barrier can be repaired on the basis of moisturizing, from skin internal pinning moisture；
5, the series of problems that scytitis brings can be alleviated.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in detail.Following example will assist in the technology of this area
Personnel are further appreciated by the present invention, but limit the present invention the most in any form.It should be pointed out that, the ordinary skill to this area
For personnel, without departing from the inventive concept of the premise, it is also possible to make some deformation and improvement.These broadly fall into the present invention
Protection domain.
Each component raw material involved by following example and comparative example is the commercially available universal product, involved experimental technique
It is method commonly used in the art.
Embodiment 1～3
The present embodiment 1-3 provides a kind of moisture-keeping composition containing Camellia oil and moisture surge treatment formula, shown moisturizing group
Component and the weight proportion of compound are as shown in table 1.
Table 1
Moisture surge treatment formula described in the present embodiment 1-3 includes each component of following weight/mass percentage composition: containing Camellia oil
Moisturizing remediation composition 20%, glycerol 6%, 1,2-pentanediol 2%, EDETATE SODIUM 0.1%, PEG-100 stearate
1.5%, glyceryl stearate 0.5%, Cholesteryl hydroxystearate 1.0%, spermol 2%, behenyl alcohol 0.5%, poly-diformazan
Radical siloxane 1.0%, cholesterol 0.2%, xanthan gum 0.3%, butanediol 3%, phenoxyethanol 0.5%, parahydroxyacet-ophenone
0.5%, hyaluronate sodium 0.05%, essence 0.1%, surplus are water.
The preparation method of described moisture surge treatment formula comprises the following steps:
A1, weigh each component, by water phase components water, glycerol, 1,2-pentanediol, EDETATE SODIUM are sequentially added into kettle, heating
To 85-95 DEG C, stir, mixing speed 15-25rpm；
A2, by oil phase component PEG-100 stearate, glyceryl stearate, Cholesteryl hydroxystearate, spermol,
Behenyl alcohol, polydimethylsiloxane, cholesterol are sequentially added into oil cauldron, are heated to 80-85 DEG C, stir, mixing speed 15-
25rpm；
A3, oil phase component is mixed with water phase components, and add the mixed liquor of xanthan gum and butanediol, homogenizing, then protect
Temperature；
Sequentially add after A4, cooling phenoxyethanol and the mixed solution of parahydroxyacet-ophenone, hyaluronate sodium water-soluble
Liquid and essence, after stirring, discharging.
In step A3, described homogenizing time is 5 minutes, and homogenizing speed is 3000rpm；Described holding temperature is 80-85 DEG C,
Temperature retention time is 30 minutes.
In step A4, when 50 DEG C, add described hyalomitome aqueous acid and essence.
Comparative example 1～7
This comparative example 1-7 provides a kind of moisture-keeping composition containing Camellia oil and moisture surge treatment formula, shown moisturizing group
Component and the weight proportion of compound are as shown in table 2.
Table 2
The preparation method of the moisture surge treatment formula described in this comparative example 1-7 is same as in Example 1.
Compliance test result
1, human body moistening effect test
Method: be divided into fugitive moisturizing to measure and the mensuration of long-acting moisturizing.30 healthy dry skin volunteers participate in
This experiment, men and women does not limits, the age 18-65 year between, within nearest three months, do not participated in any medicine, cosmetics or health care
The clinical trial of product.
1.1 fugitive moisturizings
Identify 8 regions of Instrument measuring, left and right shank mark in experimenter's left and right arm by the most ready template
Knowing 6 regions Instrument measuring, size is 4*2.5cm2；
Removing the blank district of left and right arm, use sample in all test sections, sample usage amount is 2mg/cm2；
First wash skin before basic value test, be measured again after skin is dry after 30min；Sample uses afterwards
After 1h, 2h, 4h, 6h, 8h are measured；
This test instrunment is Corneometer (CK), is used for measuring the moisture of skin；First use before test every time
Water clearing skin, is measured after after 30min, skin is dry again；
Laboratory ambient temperature controls at 22 ± 2 DEG C, and relative humidity is 50 ± 5%.
1.2 long-acting moisturizings
Identify 8 regions of Instrument measuring in experimenter's left and right arm by the most ready template, size is 4*
2.5cm2；
Remove the blank district of left and right arm, at all test sections skin marking pen labelling, respectively use once,
Using 30d sample continuously, sample usage amount is 2mg/cm2；
Other any skin care item or medicines can not be used in 30d
This test instrunment is Corneometer (CK), is used for measuring the moisture of skin；Testing time point is sample
Before using, the 1w after sample use, 2w, 3w, 4w；First wash skin before test, after skin is dry after 30min every time
It is measured (laboratory ambient temperature controls at 22 ± 2 DEG C, and relative humidity is 50 ± 5%) again, during experiment, keeps original life
Rule alive.
Moisture surge treatment formula embodiment 1-3 and comparative example 1-7 prepared carries out moistening effect checking, its experimental result such as table
3 and table 4 shown in.
Table 3. fugitive moisturizing test result
Table 4. long-acting moisturizing test result
2, skin barrier function test
30 healthy dry skin volunteers participate in this experiment (being same personnel with above two groups of experiments), men and women
Not limiting, the age, between 18-65 year, did not participated in the clinical trial of any medicine, cosmetics or health product for nearest three months.
Various inherences and external factor all can cutaneous permeability barrier, horny layer is the product of epidermis terminal differentiation,
It is possible to prevent the evaporation of moisture.What TEWL (percutaneous loss of moist) reflected is the water evaporation capacity from skin surface, is to evaluate skin
The important indicator of barrier function.
TEWL (percutaneous loss of moist) method of testing:
Identify 8 regions of Instrument measuring in experimenter's left and right arm by the most ready template, size is 4*
2.5cm2；
Remove the blank district of left and right arm, at all test sections skin marking pen labelling, respectively use once,
Using 30d sample continuously, sample usage amount is 2mg/cm2；
Other any skin care item or medicines can not be used in 30d；
This test instrunment is Corneometer (CK), is used for measuring TEWL (percutaneous loss of moist)；Testing time point is
1w, 4w before sample uses, after sample use；First wash skin before test every time, enter again after skin is dry after 30min
Row measures (laboratory ambient temperature controls at 22 ± 2 DEG C, and relative humidity is 50 ± 5%)；
Original rule of life is kept during experiment.
Moisture surge treatment formula embodiment 1-3 and comparative example 1-7 prepared carries out skin barrier function test, its experimental result
As shown in table 5.
Table 5.TEWL test result
Interpretation of result: from table 3,4,5, this programme is obvious to dry skin effect, energy moisturizing rapidly, and adheres to making
With the water content of skin can be improved, repair skin barrier, reduce moisture loss.
Embodiment 4
Present embodiments provide a kind of skin-moisturizing, skin oil, including each component of following weight/mass percentage composition: prepared by embodiment 1
The moisturizing remediation composition 70% containing Camellia oil, parahydroxyacet-ophenone 0.3%, 1,2-hexanediol 0.2%, Ku Suola reed
Luxuriant growth liquid extract 1%, hydrogenation Semen pruni armeniacae oil 1%, hair auspicious palmitic acid fruit oil 1%, tocopherol acetas 1%, macadimia nut seed oil 1%,
Wild soybean oil 1%, American Avocado Tree oil 2%, Jojoba seed oil 2%, bisabolol 0.5%, Flos Chrysanthemi extract 1%, sweet orange blossom oil
0.2%, pentaerythritol tetra (di-tert-butyl hydroxy hydrocinnamate) 0.3%, surplus are ethylhexyl palmitate.
The preparation method of the skin-moisturizing, skin oil described in the present embodiment, comprises the following steps:
B1, by ethylhexyl palmitate, parahydroxyacet-ophenone, 1,2-hexanediol is sequentially added in pot, and heated and stirred is to the completeest
CL；
B2, by Ku Suola aloe liquid extract, hydrogenation Semen pruni armeniacae oil, hair auspicious palmitic acid fruit oil, tocopherol acetas, macadimia nut
Seed oil, Wild soybean oil, American Avocado Tree oil, Jojoba seed oil, bisabolol, Flos Chrysanthemi extract, sweet orange blossom oil, tetramethylolmethane four (double-
Tert-butyl hydroxy hydrocinnamic acid) ester is sequentially added in pot, stirs；
B3, the moisturizing remediation composition containing Camellia oil is added after in pot and stir, discharging.
The speed of described stirring is 15-25rpm.
The concrete application approach of the present invention is a lot, and the above is only the preferred embodiment of the present invention.It should be pointed out that, above
Embodiment is merely to illustrate the present invention, and is not limited to protection scope of the present invention.Common skill for the art
For art personnel, under the premise without departing from the principles of the invention, it is also possible to make some improvement, these improvement also should be regarded as this
Bright protection domain.
Claims (10)
1. the moisturizing remediation composition containing Camellia oil, it is characterised in that include each group of following weight/mass percentage composition
Point:
2. the moisturizing remediation composition containing Camellia oil as claimed in claim 1, it is characterised in that include following quality hundred
Each component of point content:
3. one kind contains the moisturizing remediation composition of Camellia oil purposes in cosmetics as claimed in claim 1 or 2.
4. a moisture surge treatment formula, it is characterised in that include each component of following weight/mass percentage composition: such as claim 1 or 2 institute
The moisturizing remediation composition 20% containing Camellia oil stated, glycerol 6%, 1,2-pentanediol 2%, EDETATE SODIUM 0.1%, PEG-
100 stearates 1.5%, glyceryl stearate 0.5%, Cholesteryl hydroxystearate 1.0%, spermol 2%, behenyl alcohol
0.5%, polydimethylsiloxane 1.0%, cholesterol 0.2%, xanthan gum 0.3%, butanediol 3%, phenoxyethanol 0.5%, right
Hydroxy acetophenone 0.5%, hyaluronate sodium 0.05%, essence 0.1%, surplus are water.
5. the preparation method of a moisture surge treatment formula as claimed in claim 4, it is characterised in that comprise the following steps:
A1, weigh each component, by water phase components water, glycerol, 1,2-pentanediol, EDETATE SODIUM are sequentially added into kettle, are heated to 85-
95 DEG C, stir, mixing speed 15-25rpm；
A2, by oil phase component PEG-100 stearate, glyceryl stearate, Cholesteryl hydroxystearate, spermol, behenyl
Alcohol, polydimethylsiloxane, cholesterol are sequentially added into oil cauldron, are heated to 80-85 DEG C, stir, mixing speed 15-25rpm；
A3, oil phase component is mixed with water phase components, and add the mixed liquor of xanthan gum and butanediol, homogenizing, be then incubated；
A4, sequentially add phenoxyethanol and the mixed solution of parahydroxyacet-ophenone, the aqueous solution of hyaluronate sodium and essence, stir
After mixing uniformly, discharging.
6. the preparation method of moisture surge treatment formula as claimed in claim 5, it is characterised in that in step A3, described homogenizing time
Being 5 minutes, homogenizing speed is 3000rpm；Described holding temperature is 80-85 DEG C, and temperature retention time is 30 minutes.
7. the preparation method of moisture surge treatment formula as claimed in claim 5, it is characterised in that in step A4, when 50 DEG C, add institute
State hyalomitome aqueous acid and essence.
8. a skin-moisturizing, skin oil, it is characterised in that include each component of following weight/mass percentage composition: such as claim 1 or 2 institute
The moisturizing remediation composition 70% containing Camellia oil stated, parahydroxyacet-ophenone 0.3%, 1,2-hexanediol 0.2%, Ku Suola
Aloe liquid extract 1%, hydrogenation Semen pruni armeniacae oil 1%, hair auspicious palmitic acid fruit oil 1%, tocopherol acetas 1%, macadimia nut seed oil
1%, Wild soybean oil 1%, American Avocado Tree oil 2%, Jojoba seed oil 2%, bisabolol 0.5%, Flos Chrysanthemi extract 1%, orange blossom
Oil 0.2%, pentaerythritol tetra (di-tert-butyl hydroxy hydrocinnamate) 0.3%, surplus are ethylhexyl palmitate.
9. the preparation method of a skin-moisturizing, skin as claimed in claim 8 oil, it is characterised in that comprise the following steps:
B1, by ethylhexyl palmitate, parahydroxyacet-ophenone, 1,2-hexanediol is sequentially added in pot, and heated and stirred is to the most molten
Solve；
B2, by Ku Suola aloe liquid extract, hydrogenation Semen pruni armeniacae oil, hair auspicious palmitic acid fruit oil, tocopherol acetas, macadimia nut seed
Oil, Wild soybean oil, American Avocado Tree oil, Jojoba seed oil, bisabolol, Flos Chrysanthemi extract, sweet orange blossom oil, tetramethylolmethane four (double-uncle
Butylhydroxy hydrocinnamic acid) ester is sequentially added in pot, stirs；
B3, the moisturizing remediation composition containing Camellia oil is added after in pot and stir, discharging.
10. the preparation method of skin-moisturizing, skin oil as claimed in claim 9, it is characterised in that the speed of described stirring is 15-
25rpm。
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