CN106074737A - A kind of pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis - Google Patents
A kind of pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis Download PDFInfo
- Publication number
- CN106074737A CN106074737A CN201610655898.5A CN201610655898A CN106074737A CN 106074737 A CN106074737 A CN 106074737A CN 201610655898 A CN201610655898 A CN 201610655898A CN 106074737 A CN106074737 A CN 106074737A
- Authority
- CN
- China
- Prior art keywords
- herba
- pharmaceutical preparation
- ctenopharyngodon idellus
- fish
- bacterial enteritis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
Abstract
The present invention relates to a kind of pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis, by Herba Euphorbiae Humifusae, Herba Acalyphae, Herba polygoni hydropiperis, Herba Andrographis, garlicin and Gypsum Fibrosum drying according to a certain percentage, pulverize, be mixed and made into powder.The present invention can be used by fish per kilogram of body weight 0.2g, it is possible to adds 400g of the present invention by every 100kg bait, is uniformly mixed in bait and feeds, and the hemorrhagic disease total effective rate of prevention Ctenopharyngodon idellus is reached more than 90%.
Description
Technical field
The present invention relates to a kind of Aquatic product pharmaceutical preparation, be specifically related to a kind of pharmaceutical preparation preventing fish bacterial enteritis.
Background technology
Fish bacterial enteritis disease is the modal a kind of fish diseases in In Middle And Lower Reaches of Changjiang River, all can suffer from from fingerling to adult fish
Disease, especially Ctenopharyngodon idellus, Carassius auratus etc. are eaten feeding fish and are the most easily fallen ill.This suffering from edema temperature comes into vogue for more than 18 DEG C (the 3-10 month).25℃~
30 DEG C (6-7 months) are the epidemic peak phases.Often with bacterial gill rot disease, erythroderma etc. concurrently, be cultured fishes endanger more serious
One of disease.
Cardinal symptom: the macroscopic symptom of cyprinid fish be body surface and anus rubescent, internal organs and intestinal tube inflammation, enteral
There is mucus.Sick fish loss of appetite is not ingested, and body colour blackout, travelling slow, disease early stage, cuts intestinal wall seen from intestinal tube open
Contrafluxion inflammation, does not has food or back segment to have a small amount of food in intestinal.End-stage disease intestinal is aubergine, intestinal wall poor flexibility,
Enteral is without food, and mucus is many, anus redness evagination, is seriously that fish body intraperitoneal has flaxen ascites, is carried in disease fish head portion
Rising, existing yellow mucus flows out (this is due to blood capillary hyperemia inflammation, and expansion even ruptures excessive caused) from anus.
This disease pathogen be cause of disease be visible peristalsis visible intestinal peristalsis Aeromonas punctata, for conditioned pathogen, thalline rod-short, (0.4-0.5) is micro-
Rice × (1-1.3) micron.Gram’s staining is negative.On agar culture medium, periphery of bacterial colonies can produce brown pigment, semi-transparent
Bright, this is one of the feature of this bacterium.
All there is generation in this disease area of respectively breeding fish in the whole nation.Bacterial enteritis disease is also known as rinderpest, Aconitum carmichjaelii Debx. pestilence, the intestinal of Fish
In all there is this type of pathogenic bacteria.But in healthy fish body, this bacterium is in weak tendency, will not be diseases induced.But when by water quality environment
Deteriorate, dissolved oxygen reduce, throw something and feed the cause influence such as rotten feedstuff and bait throwing in variable interval, non-quantitative time, cause the opposing of fish body
Power declines, thus pathogen is discharged to polluted water and feedstuff in water body with the feces of fish, infects other Fish through fish mouth.Cause
This, this kind of disease was likely to occur and development in the whole culture-cycle.
Busy season morbidity of eating food in 7～JIUYUE is the most prominent.If can not treat in time when being in a bad way, mortality rate can exceed
50%, may be up to 90% time serious and cause great economic loss to breeding enterprise.The pond of bacterial enteritis disease it is susceptible to suffer from Fish
The pool, cleans up the pond with quick lime, and the quality that ensures to clean up the pond.Ensure water quality, it is to avoid use municipal sewage to breed fish；Morbidity season fish
Joint, pharmaceutical chemistry of can throwing something and feeding prevents.
Ctenopharyngodon idellus bacterial enteritis focuses on prevention.Develop a kind of medicine preventing Ctenopharyngodon idellus bacterial enteritis, have of crucial importance
Meaning.
Summary of the invention
The invention provides a kind of Aquatic product pharmaceutical preparation, be used for preventing and treating Ctenopharyngodon idellus bacterial enteritis, improve culturing economic effect
Benefit.The present invention is achieved in that a kind of pharmaceutical preparation preventing hemorrhagic disease of grass carp, it is characterised in that it is by following weight
Raw material composition: Herba Euphorbiae Humifusae 20-150g, Herba Acalyphae 30-200g, Herba polygoni hydropiperis 50-200g, Herba Andrographis 40-150g, garlicin 0.4-
1g, Gypsum Fibrosum 300～500g.
Inventive formulation is the most more preferably: Herba Euphorbiae Humifusae 100g, Herba Acalyphae 150g, Herba polygoni hydropiperis 150g, Herba Andrographis
100g, garlicin 0.5g, Gypsum Fibrosum 450g.
The pharmaceutical preparation that the present invention is above-mentioned, dosage form is powder.By said herbal medicine raw material Herba Euphorbiae Humifusae, Herba Acalyphae, Herba polygoni hydropiperis, wear
Heart lotus, garlicin and Gypsum Fibrosum powder are broken to all by No. two sieves, prepare after being sufficiently mixed.
The pharmaceutical preparation that the present invention is above-mentioned, also can contain other pharmaceutic adjuvants: such as antioxidant, preservative, carrier etc..
Using method of the present invention is: fish every 1kg body weight 0.2g, is used in conjunction 1～2 day；Or by 5% bait throwing in gauge, every 1kg feedstuff
Add this product 4g, be uniformly mixed in feedstuff and feed, be used in conjunction 1～2 day.
This prescription each component effect resolves as follows:
Herba Euphorbiae Humifusae is euphorbia plant, is a kind of Chinese crude drug, gathers in summer, season in autumn two, removes impurity, dry.Can heat clearing away solution
Poison;Dampness removing jaundice eliminating;Promoting blood circulation and hemostasis.Main dysentery, have loose bowels, jaundice;Hemoptysis;Spit blood;Hematuria;Have blood in stool;Metrorrhagia;Agalactia;Traumatic injury
Swell and ache and pathopyretic ulcer etc..
Herba Acalyphae is called: Herba Acalyphae, Acalypha australis, concha Anodonta seu Cristaria grass, Latin literary fame: AcalyphaaustralisL. is the Radix Euphorbiae Pekinensis
Section, Acalypha plant.Nearly all there is distribution in the whole of China, and the Yangtze river basin is the most.Cure mainly: heat-clearing and toxic substances removing, dampness removing, astringing to arrest bleeding.
For enteritis, dysentery, haematemesis, epistaxis, have blood in stool, hematuria, metrorrhagia, carbuncle furuncle infections, skin eczema.
Herba polygoni hydropiperis Laliao HERBA POLYGONI PUBESCENTIS this product is polygonaceae plant FUMAO knotweed Polygonum
The dry herb of pubescens Blume.Summer, season in autumn two gather, and remove impurity, cleaning, drying.Containing glycoside and tannin taste
Pungent, warm in nature.For dysentery, its fluid extract and the extract thereof such as have loose bowels are to staphylococcus aureus, bacillus pyocyaneus, hemolytic hammer
Bacterium has stronger bacteriostasis.
Herba Andrographis acanthaceous plant Herba Andrographis (circular cone palpus medicinal herbs) Andrographis paniculata (Burm. f.)
The dry aerial parts of Nees.Stem and leaf at the beginning of autumn is tapped time luxuriant, dries.Bitter in the mouth, cold in nature.GUIXIN, lung, large intestine, bladder are through taste
Hardship, cold in nature.Heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.Control acute bacillary dysentery, gastroenteritis.
Garlicin (Allicin) is to carry from the bulb (Bulbus Allii head) of Herba Alii fistulosi section allium Bulbus Allii (Allium Sativum)
A kind of organosulfur compound taken, exists in Bulbus Allii Cepae and other Herba Alii fistulosi section plants.Formal name used at school GIUCOSinoate.Greatly
Allicin is a kind of broad spectrum antibiotic, has the various biological function such as antiinflammatory, lowering blood pressure and blood fat.It addition, garlicin is used for raiseeing
Herd and aquaculture, production performance can be significantly improved, reduce sickness rate, reduce mortality rate, increase culture benefit.
Gypsum Fibrosum is monoclinic system mineral, and main chemical compositions is calcium sulfate (CaSO4), Chinese medicine is mainly used in heat clearing away and rushes down
Fire.
Above-mentioned raw materials is applied in combination by the present invention, the hemorrhagic disease of Ctenopharyngodon idellus is had good preventive effect, uses instead through user
Feedback, total effective rate reaches more than 90%.And the raw material that the present invention uses is Chinese herbal medicine and vitamin, does not results in any medicine residual
Stay, can be applicable to the adult fish that will list.
Detailed description of the invention
Embodiment 1:
A kind of Aquatic product pharmaceutical preparation, it is characterised in that it is made up of the raw material of following weight: Herba Euphorbiae Humifusae 100g, Herba Acalyphae
150g, Herba polygoni hydropiperis 150g, Herba Andrographis 100g, garlicin 0.5g, Gypsum Fibrosum 450g.
Embodiment 2:
A kind of Aquatic product pharmaceutical preparation, it is characterised in that it is made up of the raw material of following weight: Herba Euphorbiae Humifusae 100g, Herba Acalyphae
150g, Herba polygoni hydropiperis 150g, Herba Andrographis 100g, garlicin 0.5g, Gypsum Fibrosum 450g.
Embodiment 3:
A kind of Aquatic product pharmaceutical preparation, it is characterised in that it is made up of the raw material of following weight: Herba Euphorbiae Humifusae 100g, Herba Acalyphae
150g, Herba polygoni hydropiperis 150g, Herba Andrographis 100g, garlicin 0.5g, Gypsum Fibrosum 450g.
Above example starts to be raised aquaculture family, medium ground at grass by Gaoyou, Jiangsu, Zhejiang Huzhou, Jiangsu in March, 2015
Fish culture uses, bait adds above example, every 1000kg bait adds 4kg, is used in conjunction 2, use the most again, right
The bacterial enteritis of prevention Ctenopharyngodon idellus has good effect, and total effective rate reaches more than 90%, uses the medicine of the present invention to prevent
After, do not occur bacterial enteritis popular so far, Mylopharyngodon piceus and Ctenopharyngodon idellus also rarely have death.
Being described in detail the specific embodiment of the present invention above, but it is intended only as example, the present invention does not limit
It is formed on particular embodiments described above.To those skilled in the art, any equivalent modifications that the present invention is carried out and
Substitute the most all among scope of the invention.Therefore, in the impartial conversion made without departing from the spirit and scope of the invention and
Amendment, all should contain within the scope of the invention.
Claims (2)
1. the pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis, it is characterised in that it is made up of the raw material of following weight: ground
Brocade grass 20-150g, Herba Acalyphae 30-200g, Herba polygoni hydropiperis 50-200g, Herba Andrographis 40-150g, garlicin 0.4-1g, Gypsum Fibrosum 300～
500g。
A kind of pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis the most as claimed in claim 1, its formula is preferably: Herba Euphorbiae Humifusae
100g, Herba Acalyphae 150g, Herba polygoni hydropiperis 150g, Herba Andrographis 100g, garlicin 0.5g, Gypsum Fibrosum 450g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610655898.5A CN106074737A (en) | 2016-08-12 | 2016-08-12 | A kind of pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610655898.5A CN106074737A (en) | 2016-08-12 | 2016-08-12 | A kind of pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106074737A true CN106074737A (en) | 2016-11-09 |
Family
ID=57455750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610655898.5A Pending CN106074737A (en) | 2016-08-12 | 2016-08-12 | A kind of pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106074737A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111758857A (en) * | 2020-07-29 | 2020-10-13 | 四川农业大学 | Dietary composition for preventing and treating bacterial enteritis of grass carps and application thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055666A (en) * | 1986-10-27 | 1991-10-30 | 张仁威 | A kind of method of producing the fish medicine |
| CN102028853A (en) * | 2009-09-29 | 2011-04-27 | 吴维鹏 | Traditional Chinese medicine for preventing and controlling caverned disease of Japanese koi |
| CN103300224A (en) * | 2013-07-08 | 2013-09-18 | 盐城工学院 | Feed additive for preventing and treating enteritis of pikes |
| CN104138442A (en) * | 2014-07-19 | 2014-11-12 | 扬中牧乐药业有限公司 | Compound Chinese herbal medicine extracting solution preventing and treating sea eel bacterial enteritis and preparing method of compound Chinese herbal medicine extracting solution |
| CN104248701A (en) * | 2014-09-26 | 2014-12-31 | 浙江海洋学院 | Fish medicine for treating enteritis of grass carps and preparation method of fish medicine |
-
2016
- 2016-08-12 CN CN201610655898.5A patent/CN106074737A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055666A (en) * | 1986-10-27 | 1991-10-30 | 张仁威 | A kind of method of producing the fish medicine |
| CN102028853A (en) * | 2009-09-29 | 2011-04-27 | 吴维鹏 | Traditional Chinese medicine for preventing and controlling caverned disease of Japanese koi |
| CN103300224A (en) * | 2013-07-08 | 2013-09-18 | 盐城工学院 | Feed additive for preventing and treating enteritis of pikes |
| CN104138442A (en) * | 2014-07-19 | 2014-11-12 | 扬中牧乐药业有限公司 | Compound Chinese herbal medicine extracting solution preventing and treating sea eel bacterial enteritis and preparing method of compound Chinese herbal medicine extracting solution |
| CN104248701A (en) * | 2014-09-26 | 2014-12-31 | 浙江海洋学院 | Fish medicine for treating enteritis of grass carps and preparation method of fish medicine |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111758857A (en) * | 2020-07-29 | 2020-10-13 | 四川农业大学 | Dietary composition for preventing and treating bacterial enteritis of grass carps and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101961414A (en) | Medicament for preventing and curing grass carp bleeding disease | |
| CN105250406A (en) | Chinese herbal medicine fermentation extract liquid for preventing and treating viral diseases of freshwater fish and preparation method thereof | |
| CN105287790B (en) | A kind of fevervine extract and its application | |
| CN104887843B (en) | Traditional Chinese medicine composition for preventing and treating fish gill rot disease and preparation method thereof | |
| CN104208239A (en) | Traditional Chinese medicine composition for preventing and treating poultry escherichia coli disease, microecological preparation, and preparation method | |
| CN106074737A (en) | A kind of pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis | |
| CN102028816B (en) | Chinese herbal medicinal compound preparation for treating hemorrhage disease of grass carp | |
| CN103393778B (en) | Compound Chinese herbal preparation for preventing and treating fish bacteria and viral diseases | |
| CN105816565A (en) | Composition for treating enteritis of black carps | |
| CN106107215A (en) | Feed additive of Aquatic product and preparation method thereof | |
| CN108096355B (en) | Traditional Chinese medicine compound formula for treating cold-dampness type diarrhea of pigs, preparation and application | |
| CN105833075A (en) | Traditional Chinese medicine preparation for preventing rabbit haemorrhagic diseases | |
| CN105106394A (en) | Chinese herb preparation for preventing and treating animal digestive canal infection and preparing method and application thereof | |
| CN105053633A (en) | Poultry physique improving Chinese herbal medicinal composite forage and preparation method thereof | |
| CN103393891B (en) | Antiviral compound traditional Chinese medicine for animals, and preparation method and use thereof | |
| CN103800464B (en) | A kind of Chinese medicine composition for the treatment of yellow and white dysentery of piglet | |
| CN104173556A (en) | Complex preparation for treating prawn enteritis | |
| CN105213866A (en) | A kind of Chinese medicine microorganism compound preparation preventing and treating fish bacterial disease | |
| CN109432287A (en) | A kind of traditional Chinese medicine oral liquid and preparation method thereof of prevention and treatment poultry excessive heat in the system card | |
| CN101406607A (en) | Antibiotic and antiphlogistic medicine for preventing and treating bacteriosis of aquatic livestock | |
| CN104547137A (en) | Composite fermented traditional Chinese medicine composition for preventing and treating chicken infectious bursal disease | |
| CN103330855B (en) | Medicine preparation for preventing hemorrhagic disease of grass carp | |
| CN105053655B (en) | It is a kind of that a kind feed for duck brood time survival rate can be improved | |
| CN103750069A (en) | Feed additive for prevention and treatment of fish bacteria and virus diseases | |
| CN104147212A (en) | Composite preparation for treating tortoise enteritis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20161109 |
|
| WD01 | Invention patent application deemed withdrawn after publication |