CN104248701A - Fish medicine for treating enteritis of grass carps and preparation method of fish medicine - Google Patents
Fish medicine for treating enteritis of grass carps and preparation method of fish medicine Download PDFInfo
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- CN104248701A CN104248701A CN201410501381.1A CN201410501381A CN104248701A CN 104248701 A CN104248701 A CN 104248701A CN 201410501381 A CN201410501381 A CN 201410501381A CN 104248701 A CN104248701 A CN 104248701A
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Abstract
The invention discloses a fish medicine for treating the enteritis of grass carps and a preparation method of the fish medicine, and belongs to the technical field of fish medicines. The fish medicine is characterized by being prepared from the following substances in parts by weight: 85-90 parts of traditional Chinese medicinal liquid, 4-10 parts of probiotics and 3-8 parts of a synergistic ingredient. According to the fish medicine for treating the enteritis of the grass carps and the preparation method of the fish medicine, natural Chinese herb medicines are used as active components and carriers, and various Chinese herb medicines are blended, so that the fish medicine is obvious in synergistic interaction effect; the probiotics and the synergistic ingredient are good in effect of treating the enteritis of the grass carps, and the immunity of fishes can be also enhanced; the drug resistance is avoided, and no toxic and side effect is achieved; the fish medicine is convenient to use and low in cost.
Description
Technical field
The invention belongs to fish medicine technical field, be specially a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus and preparation method thereof.
Background technology
Enteritis disease is again rinderpest, Aconitum carmichjaelii Debx. pestilence, and pathogen is point-like aerogenesis monospore bacillus, and this disease is one of the most serious disease of current feeding fish apoplexy due to endogenous wind.Very general in Ctenopharyngodon idellus, mortality rate is very high, generally can reach about 50%.The epidemic season of various places and occurring degree, with change and the feeding and management level difference to some extent of weather, in 1 year, this disease has two obvious epidemic season, 5 ~ June mainly 1 ~ 2 age Ctenopharyngodon idellus morbidity season, the morbidity season of 8 ~ JIUYUE mainly Ctenopharyngodon idellus then, Prevalent district is very extensive.Sick fish is slow in action, and do not eat food, abdominal part expands, and body colour blackening, particularly head seem more black, has a lot of coelomic fluid, and intestinal wall is congested, and in bronzing, enteral does not have food, only has much flaxen mucus.As treated not in time, sick fish can die very soon.
Summary of the invention
For the above-mentioned problems in the prior art, the object of the invention is to design the technical scheme that a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus and preparation method thereof is provided, its cooperative synergism effect is obvious, good to the therapeutic effect of grass carp Ctenopharyngodon idellus, fish body immunity can also be improved, do not produce drug resistance, without any side effects, easy to use, with low cost.
Described a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus, is characterized in that being made up of the following material of parts by weight: herb liquid 85-90 part, probiotic bacteria 4-10 part, synergistic component 3-8 part;
Described herb liquid adopts following methods preparation: take Herba Euphorbiae Humifusae according to the ratio of weight ratio 2:1-3:4-6:1-2:3-7, Herba polygoni hydropiperis, Bulbus Allii, Rhizoma Coptidis, Radix litseae rubescentis add 5-6 doubly to the water soaking 4-5h of total medical material weight, then at 90-100 DEG C, 40-50min is decocted, finally cross and filter medicinal residues, collect filtrate, be concentrated into the 1/2-1/3 of filtrate original volume, for subsequent use;
Described probiotic bacteria is bacillus subtilis, bacillus bifidus, streptococcic mixture, bacillus subtilis: bacillus bifidus: streptococcic weight ratio is 1:2:1;
Described synergistic component is the mixture of vitamin A and vitamin E, vitamin A: the weight ratio of vitamin E is 1:2.
Described a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus, is characterized in that: herb liquid 85 parts, probiotic bacteria 10 parts, synergistic component 5 parts.
Described a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus, is characterized in that: herb liquid 90 parts, probiotic bacteria 4 parts, synergistic component 6 parts.
Described a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus, is characterized in that: herb liquid 88 parts, probiotic bacteria 8 parts, synergistic component 4 parts.
Described a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus, is characterized in that: the weight ratio of Herba Euphorbiae Humifusae, Herba polygoni hydropiperis, Bulbus Allii, Rhizoma Coptidis, Radix litseae rubescentis is 2:1:6:2:3.
Described a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus, is characterized in that: the weight ratio of Herba Euphorbiae Humifusae, Herba polygoni hydropiperis, Bulbus Allii, Rhizoma Coptidis, Radix litseae rubescentis is 2:3:4:1:7.
Described a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus, is characterized in that: the weight ratio of Herba Euphorbiae Humifusae, Herba polygoni hydropiperis, Bulbus Allii, Rhizoma Coptidis, Radix litseae rubescentis is according to weight ratio 2:2:5:1:5.
Described a kind of preparation method for the treatment of the fish medicine of grass carp Ctenopharyngodon idellus, is characterized in that comprising the following steps: by herb liquid, synergistic component mixed dissolution evenly, 110-130 DEG C of sterilizing 15-25min, finally adds probiotic bacteria, mix homogeneously.
Herba Euphorbiae Humifusae is the Herba Euphorbiae Humifusae of euphorbia plant, is a kind of Chinese crude drug, can heat-clearing and toxic substances removing; Dampness removing jaundice eliminating; Promoting blood circulation and hemostasis, main dysentery, have loose bowels, jaundice etc.; Containing gallic acid, Galla Turcica (Galla Helepensis) formicester, quercitrin, Quercetin, inositol and tannic acid etc., gallic acid is its main antibiotic effective ingredient.
Herba polygoni hydropiperis, annual herb, this product root hair shape, surperficial taupe brown or puce, feeble QI, taste is peppery, has removing toxic substances, damp eliminating, dissipating blood stasis, hemostasia effect, has stronger bacteriostasis to staphylococcus aureus, bacillus pyocyaneus, Hemolytic streptococcus.
Bulbus Allii, it is the general designation of Bulbus Allii class plant, semi-annual herbaceous plant, Liliaceae Allium, be used as medicine with bulb, in Bulbus Allii, sulfur-containing compound has strong antibacterial and anti-inflammation functions, and all having suppression and killing action to multiple coccus, bacillus, fungus and virus etc., is the one that in the natural plants of current discovery, antibacterial action is the strongest.
Rhizoma Coptidis, belongs to Ranunculaceae, Coptis herbaceos perennial, has the effect such as antibacterial, antifungal, antiviral, anti-ameba, antiinflammatory, diarrhea, antiulcer.
Radix litseae rubescentis is a kind of Chinese crude drug, is the root of canella red autumnal leaves Fructus Litseae pungentis, have dispel the wind, effect of cold expelling, vital energy regualting and blood circulation-promoting, except rheumatism; Control vomiting and dirarrhea, trusted subordinate's distending pain, rheumatic arthralgia, traumatic injury.
Probiotic bacteria is the active microorganism that a class is useful to host, by stimulating the immune function in intestinal, too low or too high immunocompetence can be adjusted to normal condition, probiotic bacteria can suppress harmful bacteria in the breeding of enteral, reduce toxin, promote intestinal peristalsis promoting, thus improve intestinal function.
Synergistic component is the mixture of vitamin A and vitamin E, vitamin E is the important nutrient substance of fish, its major function is antioxidation, with protect fat-soluble cell membrane and unsaturated fatty acid not oxidized, in feedstuff, appropriate interpolation can as immunostimulant material, strengthen the phagocytosis of cell, strengthen cytophagous generation; Vitamin A is required to the immune normal function of Ctenopharyngodon idellus, can improve the phagocytic activity of fish body endolymph cell and the vigor of serum lysozyme and specific complement, thus produces material impact to its immune function.
Above-mentioned a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus and preparation method thereof, with natural Chinese herbal medicine for active component and carrier, various combined Chinese herb is made, and has significant cooperative synergism effect, adds probiotic bacteria, potentiation composition, good to the therapeutic effect of grass carp Ctenopharyngodon idellus, fish body immunity can also be improved, do not produce drug resistance, without any side effects, easy to use, with low cost.
The percentage composition related in present specification unless otherwise indicated, other be weight percentage.
Detailed description of the invention
Below by way of specific embodiment, the invention will be further described, and further illustrate beneficial effect of the present invention in conjunction with the test of pesticide effectiveness.
Embodiment 1
Take Herba Euphorbiae Humifusae 5kg, Herba polygoni hydropiperis 2.5kg, Bulbus Allii 15 kg, Rhizoma Coptidis 5kg, Radix litseae rubescentis 0.75kg add 5 times to the water soaking 4h of total medical material weight, then at 100 DEG C, decoct 40min, finally cross and filter medicinal residues, collect filtrate, be concentrated into 1/3 of filtrate original volume, obtained herb liquid is for subsequent use; In stirred tank, drop into 850g herb liquid, then add dehydroretinol 0g, vitamin E 40g mixed dissolution is even, 110 DEG C of sterilizing 15min, finally add 25g bacillus subtilis, 50g bacillus bifidus, 25g streptococcus, mix homogeneously final products.
Embodiment 2
Take Herba Euphorbiae Humifusae 7.5kg, Herba polygoni hydropiperis 3.75kg, Bulbus Allii 22.5 kg, Rhizoma Coptidis 7.5kg, Radix litseae rubescentis 1.125kg add 6 times to the water soaking 5h of total medical material weight, then at 100 DEG C, 50min is decocted, finally cross and filter medicinal residues, collect filtrate, be concentrated into 1/3 of filtrate original volume, obtained herb liquid is for subsequent use; In stirred tank, drop into 900g herb liquid, then add dehydroretinol 0g, vitamin E 40g mixed dissolution is even, 120 DEG C of sterilizing 20min, finally add 10g bacillus subtilis, 20g bacillus bifidus, 10g streptococcus, mix homogeneously final products.
Embodiment 3
Take Herba Euphorbiae Humifusae 2kg, Herba polygoni hydropiperis 3kg, Bulbus Allii 4 kg, Rhizoma Coptidis 1kg, Radix litseae rubescentis 7kg add 6 times to the water soaking 5h of total medical material weight, then at 100 DEG C, decoct 50min, finally cross and filter medicinal residues, collect filtrate, be concentrated into 1/2 of filtrate original volume, obtained herb liquid is for subsequent use; In stirred tank, drop into 880g herb liquid, then add retinol1 3g, vitamin E2 7g mixed dissolution is even, 130 DEG C of sterilizing 25min, finally add 20g bacillus subtilis, 40g bacillus bifidus, 20g streptococcus, mix homogeneously final products.
Embodiment 4
Take Herba Euphorbiae Humifusae 2kg, Herba polygoni hydropiperis 2kg, Bulbus Allii 5 kg, Rhizoma Coptidis 1kg, Radix litseae rubescentis 5kg add 5 times to the water soaking 4h of total medical material weight, then at 100 DEG C, decoct 45min, finally cross and filter medicinal residues, collect filtrate, be concentrated into 1/2 of filtrate original volume, obtained herb liquid is for subsequent use; In stirred tank, drop into 1320g herb liquid, then add retinol1 7g, vitamin E 41g mixed dissolution is even, 125 DEG C of sterilizing 25min, finally add 30g bacillus subtilis, 60g bacillus bifidus, 30g streptococcus, mix homogeneously final products.
Adopt this fish medicine to treat the using method of grass carp Ctenopharyngodon idellus: according to every mu of pond 5-8kg fish survival dose, every natural gift upper and lower noon throws something and feeds for 2 times, connect and feed 5-6 days.
Beneficial effect of the present invention is further illustrated below in conjunction with the test of pesticide effectiveness.
Test 1:
Select 4 groups of Ctenopharyngodon idellus suffering from enteritis, often organize 10, adopt embodiment 1-4 to process according to amount of application respectively, every natural gift upper and lower noon throws something and feeds for 2 times, connects and feeds 6 days.Test and within 6 days, add up effective, effective, the invalid quantity of grass carp Ctenopharyngodon idellus treatment afterwards, calculate its total effective rate (%); Adopt Herba Euphorbiae Humifusae, Herba polygoni hydropiperis, Bulbus Allii, Rhizoma Coptidis, Radix litseae rubescentis herb liquid and probiotic bacteria, synergistic component to prepare the fish medicine of single Chinese medicine ingredients according to the method for the invention respectively, respectively 5 groups of enteritis Ctenopharyngodon idellus are treated, the same the present invention of usage and dosage.Result of the test is in table 1
The various preparation of table 1 is to the therapeutic effect table of grass carp Ctenopharyngodon idellus
| Process | Ill Ctenopharyngodon idellus number | Effective | Effectively | Invalid | Total effective rate (%) |
| Embodiment 1 | 10 | 8 | 2 | 0 | 100 |
| Embodiment 2 | 10 | 7 | 3 | 0 | 100 |
| Embodiment 3 | 10 | 9 | 1 | 0 | 100 |
| Embodiment 4 | 10 | 10 | 10 | 0 | 100 |
| Humifuse euphorbia herb Chinese medicine preparation | 10 | 1 | 3 | 6 | 40% |
| Herba polygoni hydropiperis Chinese medicine preparation | 10 | 2 | 1 | 7 | 30% |
| Bulbus Allii Chinese medicine preparation | 10 | 2 | 2 | 6 | 40% |
| Rhizoma Coptidis Chinese medicine preparation | 10 | 1 | 1 | 8 | 20% |
| Radix litseae rubescentis Chinese medicine preparation | 10 | 1 | 2 | 7 | 30% |
Result of the test shows: embodiment 1-4 has good curative effect to grass carp Ctenopharyngodon idellus, and embodiment 4 is better than embodiment 3, and embodiment 1 is better than embodiment 2, and total effective rate is 100%; And adopt the total effective rate of humifuse euphorbia herb Chinese medicine preparation to be 40%, the total effective rate of Herba polygoni hydropiperis Chinese medicine preparation is 30%, the total effective rate of Bulbus Allii Chinese medicine preparation is 40%, the total effective rate of Rhizoma Coptidis Chinese medicine preparation is 20%, Radix litseae rubescentis Chinese medicine preparation total effective rate is 30%, this shows, the fish medicine adopting complex preparation of the present invention to obtain is very remarkable to the therapeutic effect of grass carp Ctenopharyngodon idellus, and various Chinese herbal medicine has significant cooperative synergism effect.
Claims (8)
1. treat a fish medicine for grass carp Ctenopharyngodon idellus, it is characterized in that being made up of the following material of parts by weight: herb liquid 85-90 part, probiotic bacteria 4-10 part, synergistic component 3-8 part;
Described herb liquid adopts following methods preparation: take Herba Euphorbiae Humifusae according to the ratio of weight ratio 2:1-3:4-6:1-2:3-7, Herba polygoni hydropiperis, Bulbus Allii, Rhizoma Coptidis, Radix litseae rubescentis add 5-6 doubly to the water soaking 4-5h of total medical material weight, then at 90-100 DEG C, 40-50min is decocted, finally cross and filter medicinal residues, collect filtrate, be concentrated into the 1/2-1/3 of filtrate original volume, for subsequent use;
Described probiotic bacteria is bacillus subtilis, bacillus bifidus, streptococcic mixture, bacillus subtilis: bacillus bifidus: streptococcic weight ratio is 1:1-2:1;
Described synergistic component is the mixture of vitamin A and vitamin E, vitamin A: the weight ratio of vitamin E is 1:1-2.
2. a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus as claimed in claim 1, is characterized in that: herb liquid 85 parts, probiotic bacteria 10 parts, synergistic component 5 parts.
3. a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus as claimed in claim 1, is characterized in that: herb liquid 90 parts, probiotic bacteria 4 parts, synergistic component 6 parts.
4. a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus as claimed in claim 1, is characterized in that: herb liquid 88 parts, probiotic bacteria 8 parts, synergistic component 4 parts.
5. a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus as claimed in claim 1, is characterized in that: the weight ratio of Herba Euphorbiae Humifusae, Herba polygoni hydropiperis, Bulbus Allii, Rhizoma Coptidis, Radix litseae rubescentis is 2:1:6:2:3.
6. a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus as claimed in claim 1, is characterized in that: the weight ratio of Herba Euphorbiae Humifusae, Herba polygoni hydropiperis, Bulbus Allii, Rhizoma Coptidis, Radix litseae rubescentis is 2:3:4:1:7.
7. a kind of fish medicine for the treatment of grass carp Ctenopharyngodon idellus as claimed in claim 1, is characterized in that: the weight ratio of Herba Euphorbiae Humifusae, Herba polygoni hydropiperis, Bulbus Allii, Rhizoma Coptidis, Radix litseae rubescentis is for according to weight ratio 2:2:5:1:5.
8. a kind of preparation method for the treatment of the fish medicine of grass carp Ctenopharyngodon idellus as claimed in claim 1, is characterized in that comprising the following steps: herb liquid, synergistic component mixed dissolution is even, and 110-130 DEG C of sterilizing 15-25min, finally adds probiotic bacteria, mix homogeneously.
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| CN201410501381.1A CN104248701A (en) | 2014-09-26 | 2014-09-26 | Fish medicine for treating enteritis of grass carps and preparation method of fish medicine |
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| CN201410501381.1A CN104248701A (en) | 2014-09-26 | 2014-09-26 | Fish medicine for treating enteritis of grass carps and preparation method of fish medicine |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535579A (en) * | 2015-12-19 | 2016-05-04 | 界首市众鑫科技服务有限公司 | Medicament for preventing and curing ricefield eel enteritis |
| CN106074737A (en) * | 2016-08-12 | 2016-11-09 | 镇江天和生物技术有限公司 | A kind of pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis |
| CN107743901A (en) * | 2017-10-31 | 2018-03-02 | 合肥申仁养殖有限公司 | A kind of cultural method for reducing the Penaeus Vannmei incidence of disease |
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| CN101983582A (en) * | 2010-11-24 | 2011-03-09 | 广州市海维饲料有限公司 | Traditional Chinese medicine microecological preparation for preventing and treating enteritis of grass carp and preparation method thereof |
| CN103300224A (en) * | 2013-07-08 | 2013-09-18 | 盐城工学院 | Feed additive for preventing and treating enteritis of pikes |
| CN103461728A (en) * | 2013-09-29 | 2013-12-25 | 湛江粤华水产饲料有限公司 | Mixed feed capable of preventing enteritis of golden pomfret and preparing method of mixed feed |
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2014
- 2014-09-26 CN CN201410501381.1A patent/CN104248701A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101983582A (en) * | 2010-11-24 | 2011-03-09 | 广州市海维饲料有限公司 | Traditional Chinese medicine microecological preparation for preventing and treating enteritis of grass carp and preparation method thereof |
| CN103300224A (en) * | 2013-07-08 | 2013-09-18 | 盐城工学院 | Feed additive for preventing and treating enteritis of pikes |
| CN103461728A (en) * | 2013-09-29 | 2013-12-25 | 湛江粤华水产饲料有限公司 | Mixed feed capable of preventing enteritis of golden pomfret and preparing method of mixed feed |
Non-Patent Citations (1)
| Title |
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| 胡元亮主编: "《新编中兽医验方与妙用》", 28 February 2009 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535579A (en) * | 2015-12-19 | 2016-05-04 | 界首市众鑫科技服务有限公司 | Medicament for preventing and curing ricefield eel enteritis |
| CN106074737A (en) * | 2016-08-12 | 2016-11-09 | 镇江天和生物技术有限公司 | A kind of pharmaceutical preparation preventing Ctenopharyngodon idellus bacterial enteritis |
| CN107743901A (en) * | 2017-10-31 | 2018-03-02 | 合肥申仁养殖有限公司 | A kind of cultural method for reducing the Penaeus Vannmei incidence of disease |
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