CN104800317A - Chinese medicinal composition for preventing and treating chicken coccidiosis and preparation method - Google Patents
Chinese medicinal composition for preventing and treating chicken coccidiosis and preparation method Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition for preventing and treating chicken coccidiosis and a preparation method, and belongs to the field of preparation of veterinary medicine. The Chinese medicinal composition consists of the following medicinal materials in parts by weight: 8-12 parts of sweet wormwood herb, 1-3 parts of hairyvein agrimony, 1-3 parts of Chinese arborvitae twig, 1-3 parts of hawthorn, 1-3 parts of coptis root. Poplar bark lipid is 10-40 percent based on the total weight of the composition. The method comprises the following steps: performing water decoction and concentration to prepare extract; drying to prepare particles, wherein the particle size is that particles can pass through a sieve of 100-200 meshes. The efficiency is increased and toxins are reduced through the Chinese medicinal composition; each medical component is matched together, so that coccidium and coccidian in chicken can be killed rapidly, complete curing is realized, and the toxic and side effects are small.
Description
Technical field
The invention belongs to veterinary drug preparation field, relate to a kind of Chinese medicine composition and preparation method of prevention and therapy Eimeria species particularly.
Background technology
Chicken coccidiosis parasitizes a kind of protozoacide caused in Intestinum Gallus domesticus epithelial cell by coccidiosis.The distribution of this disease is wide, harm is large, and be one of disease of the serious harm poultry husbandry of global prevalence, in various fowl disease, the incidence rate of coccidiosis is very high, the development of serious threat aviculture.It is reported, the year consumption of whole world anticoccidial drug is up to 3,300,000,000 dollars, and the multiple chickling being born in 15 ~ 50 ages in days of this disease, M & M is all higher.Intensive chicken farm is easy to break out coccidiosis, and its sickness rate is 50% ~ 70%, and up to 80% time serious, mortality rate can reach 20%, not only causes feed cost greatly to increase, and also has many secondary diseases and complication, brings serious economic loss.
Chicken coccidiosis mainly relies on chemicals to prevent and treat, and conventional coccidiosis medicine is as the medicine such as diclazuril, Maduramicin, and because life-time service creates drug resistance, curative effect is declined, coccidiosis drug resistance problems brings very burden to clinical prevention.
Chinese herbal medicine has toxic and side effects little in control chicken coccidiosis, the feature that medicine not easily remains and develops immunity to drugs, and has good development prospect.Chinese herbal medicine often makes powder and decoction in control chicken coccidiosis, mixes in feedstuff or is mixed in drinking-water and carry out administration.Although simple to operate, onset is comparatively slow, DeGrain, therefore changes Chinese herbal medicine dosage form and also plays an important role in raising control chicken coccidiosis effect.
Summary of the invention
The invention provides Chinese medicine composition and the preparation method of a kind of prevention and therapy coccidiosis, the present invention is by the principle of " efficacy enhancing and toxicity reducing ", and each pharmaceutical compositions compatibility, can kill rapidly the coccidiosis in chicken body and coccidiosis ovum, thoroughly cure, and have no side effect.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine composition of prevention and therapy Eimeria species, combined by weight by following Chinese medicinal ingredients: Herba Artemisiae Annuae 8 ~ 12 parts, Herba Agrimoniae 1 ~ 3 part, Cacumen Platycladi 1 ~ 3 part, Fructus Crataegi 1 ~ 3 part, Rhizoma Coptidis 1 ~ 3 part, poplar bark lipoid is 10 ~ 40% of composition total weight, after water boiling concentration, drying is prepared into granule, and the final content of combination of Chinese medicine thing is controlled at 50 ~ 65% (percentage by weights).
A kind of preparation method of Chinese medicine composition of prevention and therapy Eimeria species, by described 8 ~ 12 portions of Herba Artemisiae Annuaes, 1 ~ 3 part of Herba Agrimoniae, 1 ~ 3 portion of Cacumen Platycladi, 1 ~ 3 portion of Fructus Crataegi, after 1 ~ 3 part of Rhizoma Coptidis water drug-decocting concentrating liquid prepares extractum, drying is prepared into granule, medicinal residues crushed after being dried after extraction, poplar bark lipoid fully mixes with the form of evenly spraying and dried drug ground-slag, its addition is 10 ~ 40% of described compositions gross weight, after crossing 100 ~ 200 mesh sieves, the medicinal residues powder adding poplar bark lipoid is fully mixed according to weight ratio 1:1 with the granule prepared by water drug-decocting concentrating liquid, the final content of combination of Chinese medicine thing controls at 50 ~ 65% (percentage by weights).
The using method of described Chinese medicine composition, add 10 ~ 40 grams of described compositionss according to per kilogram feedstuff in feedstuff during use, mixed feeding 3 ~ 5 days is a course for the treatment of.
Herbal control coccidiosis demonstrates good momentum, not only can prevent and treat coccidiosis, also can solve broiler drug residue problem, have good development prospect.As Herba Artemisiae Annuae is proved to be a kind of Chinese herbal medicine with good Anti-human globulin test, and distributed more widely, and all there is growth China various places, draw materials conveniently, cheap.
Herba Artemisiae Annuae is the herb of feverfew Herba Artemisiae Annuae, common name Herba Artemisiae annuae, and property is bitter, cold, has clearing away summer-heat, removes the effects such as steaming, malaria, all on the books in the medical science ancient books and records such as Compendium of Material Medica, Shennong's Herbal and handbook of Prescription for Emergency.1971, China scientific research personnel took the lead in being separated from Chinese herbal artemisia obtaining anti-malaria medicaments, and called after arteannuin.In recent years, Herba Artemisiae Annuae and extract thereof, in the control of chicken coccidiosis, achieve good effect.Ma Tingfa reports, arteannuin has good Anti-human globulin test, and with other drug without cross resistance.The experimental studies such as Guo Jianying show, Herba Artemisiae Annuae 2% and 5% is added in daily ration of broiler, its anticoccidial index (ACI) is respectively 161.8 and 179.2, higher than corresponding Herba Ecliptae and Radix Et Rhizoma Rhei interpolation group (ACI is 145 ~ 160), a little less than Western medicine group (185.4), and Herba Artemisiae Annuae can improve packed cell volume value, improve body weight increase rate, obviously alleviate the various clinical symptoms of coccidiosis.Huang Cuijiao research shows, the effect of the prevention and therapy coccidiosis of Herba Artemisiae Annuae and compound Chinese herb thereof is all better than Western medicine group, and from cost accounting aspect, the cost of Chinese drug-treated group reduces >50% than Western medicine group, has a good application prospect.Lin Jiangwei prevents and treats chicken coccidiosis by chemicalses such as various dose " ball goes out " granule (Chinese herbal and crude drugs preparations based on Herba Artemisiae Annuae) and jungle fowl coccidia powders and makes comparisons, determine the treatment of chicken coccidiosis optimal clinical and preventive dose, wherein " ball goes out " granule 0.16% drinking water administration can reach good treatment chicken coccidiosis effect, its ACI is 163.21, suitable with chicken coccidia powder ACI (161.34).The reports such as Xia Yingjie, by adopting the fresh Herba Artemisiae Annuae full phase to feed to the chicken of plumage more than 100,000, control coccidiosis achieves good effect, also reduces the generation of other diseases simultaneously.About the anticoccidial effect of Herba Artemisiae Annuae also has different results of study, have minority experimental study to show, the anticoccidial effect of Herba Artemisiae Annuae is not very good.The research such as Meng Wei shows, Herba Artemisiae Annuae can not prevent the generation of the reduction of rate of body weight gain and the appearance of hemafecia and caecum lesion and egg capsule, and ACI is all far below 160, and in test, Herba Artemisiae Annuae is not fine to the preventive effect of Eimeria Tenella disease.
Containing volatile oil, trace element, agrimonine, organic acid, tannin, phenolic compound, flavonoid and glucosides class etc., Multiple components in Herba Agrimoniae, its blood drug level is in 33.33-39.33%g (crude drug)/L (blood) scope.Clinically, Herba Agrimoniae is mainly used in disease and the gynopathic treatments such as hemostasis, antitumor, urinary system, breathing, digestive system.Herba Agrimoniae water extract is mainly containing the trace element such as more glucose glycoside, calcium and phosphorus and a small amount of phenols and tannin.There is research display, the anastalsis of Herba Agrimoniae may have vasoconstrictive with it, to increase Ca2+ concentration and platelet counts etc. machine-processed relevant.Its anticoagulant had, antiplatelet effects may with suppression thromboxane element, to reduce coagulation factor activity etc. relevant, but effective ingredient is not clear.Platelet and thrombin are played an important role in hemostasis and thrombosis, the activation of platelet overactivity and blood coagulation system then easily causes thrombosis, otherwise then have hemorrhage danger, therefore platelet and blood coagulation system are the pathophysiological basis of various hemorrhagic or thrombotic disease extremely.
Cacumen Platycladi is the browse of Cupressaceae plant Cacumen Platycladi.Medical material Cacumen Platycladi Duo You branch, little and different in size, be flakey.Color is bronzing.The visible leaf in surface mutually to life, section yellow-white.Quality is crisp, easily fractureed.Feeble QI is fragrant, and the one in the blood-cooling hemostatic of bitter and puckery flavor Chinese medicine hemorrhage, has effect that hemostasis, black beard and hair, cough-relieving are breathed heavily.Cacumen Platycladi and contained flavonoid thereof have antitussive, phlegm-dispelling functions to mice, are separated its effective ingredient, and contained alcoholic Saponin phlegm-dispelling functions is comparatively strong, and its town expectorant composition may be a kind of phenol glycoside.Have obvious analgesic activity after contained flavone 250 mgs/kg of lumbar injections in leaf, 200 mgs/kg of lumbar injections and 1000 mgs/kg orally have obvious phlegm-dispelling functions.No. II, the live part extract in leaf (ethyl acetate extract) 250 mgs/kg of lumbar injections have obvious antitussive effect, and 100 and 200 mgs/kg have obvious phlegm-dispelling functions.Cacumen Platycladi also can make mice tracheal smooth muscle loose, and part blocks acetylcholine is to the effect of smooth muscle.The anesthetic action of pentobarbital sodium can be worked in coordination with, have maincenter sedation.In addition, also can diastole exsomatize intestinal segment smooth muscle, and trivial solution is except histamine and enterospasm caused by acetylcholine, gives in advance, cause pain effect both capable of blocking, also can obviously expand rabbit ear blood vessel, reduce blood pressure.Cacumen Platycladi all can suppress staphylococcus aureus, Staphylococcus albus, micrococcus catarrhalis, dysentery bacterium, Bacillus typhi, too enterobacteria etc., also has influenza, Coxsackie virus effect.
Fructus Crataegi is circular piece, and shrinkage is uneven, diameter 1 ~ 2.5cm, thick 0.2 ~ 0.4cm.Crust is red, and tool wrinkle, has canescence fleck.Sarcocarp buff is to light brown.Middle part transverse section tool 5 light yellow pits, but core comes off and hollow more.Carpopodium short and thin as seen on some sheets or calyx vestiges.Feeble QI delicate fragrance, property is sour, sweet, tepor.Return spleen, stomach, Liver Channel.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, obstruction of qi in the chest and cardialgia, hernia pain, hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well.
Rhizoma Coptidis is the dry rhizome of ranunculaceae plant Rhizoma Coptidis Coptis chinensis Franch. Coptis deltoidea C.Y.Cheng et Hsiao Coptisdeltoidea C.Y.Chenget Hsiao or Coptis Teeta Wall Coptis teeta Wall..Perennial herb, rhizome has branch, and shape is as chicken feet.Phyllopodium is raw, has long handle; Blade ovum shape triangle, three totally cleave, and central sliver prismatic, feather drastic crack, there is sawtooth at edge.Property bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.The diseases such as, vomiting damp and hot for retention of damp-heat in the interior, the intestines and stomach, dysentery.Join Radix Scutellariae, Radix Et Rhizoma Rhei etc., the card of retention of damp-heat in the interior can be controlled.Be reluctant to leave the intestines and stomach to damp and hot, often coordinate the Rhizoma Pinelliae, Caulis Bambusae In Taenia; Join the Radix Aucklandiae, Radix Scutellariae, Radix Puerariae etc. to control dysentery.For epidemic febrile disease high heat, thirsty agitation, bleeding due to blood-heat and pathopyretic ulcer etc.Control the high heat of epidemic febrile disease, hyperactivity of heart-fire, compatibility Fructus Gardeniae, Fructus Forsythiae etc.; For bleeding due to blood-heat, can compatibility Radix Scutellariae, Radix Et Rhizoma Rhei is equivalent uses; To pathopyretic ulcer, can the medicine such as compatibility Radix Paeoniae Rubra, Cortex Moutan with using.In addition, Rhizoma Coptidis also can be used for disappearing in excessiveness of stomach-fire card, can coordinate the equivalent use of Radix Trichosanthis, the Rhizoma Anemarrhenae, the Radix Rehmanniae; Be coated with mouth, can aphtha of the mouth and tongue be controlled.
Poplar bark lipoid (Poplar Bark Lipid, PBL) be the orange-yellow liposoluble substance of one extracted from Cortex Populi Davidianae, be a kind of natural complex mixture, be rich in the materials such as a large amount of polysaccharide, organic acid, sterol, phospholipid, glycoside and vitamin.Polysaccharide has the reaction of short thymic humoral, stimulates reticuloendothelial system, improves body specific immune response ability; Organic acid has the effect of enhancing human body immunity function, can stimulate and promote Function of mononuclear phagocyte, and antagonism immunosuppressant is to the inhibitory action of immune organ; Glycoside can accelerate generation, the promotion lymphocyte transformation of antibody and strengthen the effects such as reticuloendothelial system function.The coordinating and unifying in animal body of these materials, improves the immune function of animal body greatly.Poultry Main Immune Organs such as fabricius bursa, thymus, spleen, caecum and the tonsil etc. of being injected poplar bark lipoid by immunoreation sections observation create strong immune response.Therefore, can determine that poplar bark lipoid has stronger immunological enhancement.With the poplar bark lipoid treatment rabbit of 25%, find during cattle scabies, lipoid has the stronger effect to crust intradermal penetration, this effect is advantageous particularly to the affected part not carrying out crust process, it can be very fast infiltration crust inside play a part to kill acarid, lipoid also has itching-relieving action faster, about through 3 after coating, 4 hours, infected animal becomes quiet, no longer include the phenomenon that bites, lipoid also has destruction to acarid ovum, after coating 3 hours, microscopy pars affecta skin, acarid is mostly dead, acarid ovum is out of shape, after 6 hours, without the demodicid mite that lives, after coating 24 hours, affected part crust major part comes off, skin starts healing.
The research of these mechanism, assists antibody to be used for some poultry disease of prevention and therapy for poplar bark lipoid and provides theories integration.
For the immune effect of poplar bark lipoid, we prove early-stage Study, and poplar bark lipoid is as the immunostimulant improving immunity of organisms, and be also subject to the strict impact of dosage, its immune induction effect has amphicheirality.Appropriate dosage has the immunological enhancement of forward, and the additive capacity of poplar bark lipoid affects the responsing reaction degree of Immune Organs of Body.In addition, we are used for poplar bark lipoid to find in feeding of broiler process as feed additive, and except can improving broiler growth effect, the chicken group of lipoid of feeding is than the chicken group without lipoid, and its coccidiosis sickness rate obviously reduces.Further test proves, no matter body is interior or external for poplar bark lipoid, to Eimeria species, especially sick to Eimeria Tenella, has the significant egg capsule that suppresses and produces and therapeutic effect.
The present invention utilizes poplar bark lipoid to mix with Herba Artemisiae Annuae, Herba Agrimoniae, Cacumen Platycladi, Fructus Crataegi, Rhizoma Coptidis etc. exactly, prepares a kind of anticoccidial drug all kinds of Eimeria species to significant prevention and therapy effect.
The combination principle of Chinese medicine composition is " efficacy enhancing and toxicity reducing ", and therefore, the pharmacological action that the different medicine of compatibility embodies is also different.Said medicine compatibility, Herba Artemisiae Annuae, Herba Agrimoniae, Cacumen Platycladi, Fructus Crataegi, Rhizoma Coptidis, five medicines phases 5, comprehensive anticoccidial hemostasis, treating both the principal and secondary aspects of a disease, strengthening vital QI to eliminate pathogenic factors.
The present invention's beneficial effect compared with prior art: the present invention is with anticoccidial, hemostasis, raising immunity of organisms, reparation function of intestinal canal for the rule for the treatment of, and reasonable recipe, preparation technology is simple, applied widely.The present invention adopts pure Chinese medicinal herbs to make, and wide material sources, cost are low, and cure rate is high, and medicine noresidue, has no side effect, and particularly extracting with crossing decocting, maintaining Chinese medicine technique, is easier to absorb.Have significant anthelmintic, dampness removing hemostasis, the effect of temperature compensation gastrointestinal and adjustment body function, effectively all kinds of coccidiosis for the treatment of, shortens the period of convalescence.Easy to use.Clinical trial proves, cure rate reaches more than 90%, has unique curative effect.
Detailed description of the invention
Below in conjunction with preferred embodiment, to according to detailed description of the invention provided by the invention, details are as follows:
Embodiment 1
By weight 8000g:1000g:1000g:1000g:1000g, take Herba Artemisiae Annuae, Herba Agrimoniae, Cacumen Platycladi, Fructus Crataegi, Rhizoma Coptidis, above five tastes Chinese herbal medicine is decocted with water 1 time, each 0.5 hour, collecting decoction, filter, filtrate is concentrated into paste, with sucrose, dextrin, and mixing, make granule, dry; Medicinal residues after decocting are dried and are pulverized, and cross 100 mesh sieves, and poplar bark lipoid is sprayed on the medicinal residues powder surface pulverized and sieved, and mixing, dries, make medicinal residues powder; 1000g granule is fully mixed with 1000g medicinal residues powder, between mixing period, spray poplar bark lipoid, make poplar bark lipoid final concentration be 10% of composition total weight, the final content of combination of Chinese medicine thing, at 50 ~ 65% (percentage by weights), mixes rear subpackage; During chicken coccidiosis all kinds of for prevention and therapy, in feedstuff, add 10g according to per kilogram feedstuff, mixed feeding, is used in conjunction 3 days.
Embodiment 2
By weight 9000g:1500g:1500g:1000g:1000g, take Herba Artemisiae Annuae, Herba Agrimoniae, Cacumen Platycladi, Fructus Crataegi, Rhizoma Coptidis, above five tastes Chinese herbal medicine is decocted with water 1 time, each 1.0 hours, collecting decoction, filter, filtrate is concentrated into paste, with sucrose, dextrin, and mixing, make granule, dry; Medicinal residues after decocting are dried and are pulverized, and cross 200 mesh sieves, and poplar bark lipoid is sprayed on the medicinal residues powder surface pulverized and sieved, and mixing, dries, make medicinal residues powder; 1500g granule is fully mixed with 1500g medicinal residues powder, between mixing period, spray poplar bark lipoid, make poplar bark lipoid final concentration be 20% of composition total weight, the final content of combination of Chinese medicine thing, at 50 ~ 65% (percentage by weights), mixes rear subpackage; During chicken coccidiosis all kinds of for prevention and therapy, in feedstuff, add 20g according to per kilogram feedstuff, mixed feeding, is used in conjunction 4 days.
Embodiment 3
By weight 10000g:2000g:1000g:1500g:1500g, take Herba Artemisiae Annuae, Herba Agrimoniae, Cacumen Platycladi, Fructus Crataegi, Rhizoma Coptidis, above five tastes Chinese herbal medicine is decocted with water 1 time, each 1.5 hours, collecting decoction, filter, filtrate is concentrated into paste, with sucrose, dextrin, and mixing, make granule, dry; Medicinal residues after decocting are dried and are pulverized, and cross 150 mesh sieves, and poplar bark lipoid is sprayed on the medicinal residues powder surface pulverized and sieved, and mixing, dries, make medicinal residues powder; 2000g granule is fully mixed with 2000g medicinal residues powder, between mixing period, spray poplar bark lipoid, make poplar bark lipoid final concentration be 40% of composition total weight, the final content of combination of Chinese medicine thing, at 50 ~ 65% (percentage by weights), mixes rear subpackage; During chicken coccidiosis all kinds of for prevention and therapy, in feedstuff, add 30g according to per kilogram feedstuff, mixed feeding, is used in conjunction 5 days.
Embodiment 4
By weight 10000g:2000g:1000g:1500g:1500g, take Herba Artemisiae Annuae, Herba Agrimoniae, Cacumen Platycladi, Fructus Crataegi, Rhizoma Coptidis, above five tastes Chinese herbal medicine is decocted with water 1 time, each 1.5 hours, collecting decoction, filter, filtrate is concentrated into paste, with sucrose, dextrin in right amount, and mixing, make granule, dry; Medicinal residues after decocting are dried and are pulverized, and cross 150 mesh sieves, and mixing is dried, made medicinal residues powder; 2000g granule is fully mixed with 2000g medicinal residues powder, subpackage after mixing; The final content of combination of Chinese medicine thing is at 50 ~ 65% (percentage by weights), and during chicken coccidiosis all kinds of for prevention and therapy, in feedstuff, add 30g according to per kilogram feedstuff, mixed feeding, is used in conjunction 5 days.
Clinical trial:
Example 1:
Laishan chicken farm, Yantai, AA broiler
This is flat supports AA broiler 10000, raises to 20 ages in days and occurs dysentery, drawstring bloody stool just, inappetence, sickness rate 30%, mortality rate 12%.Clinical and laboratory diagnosis is coccidium infection, and the oral anticoccidial drug of broiler of 1/2 is as Toltrazuril etc., and have certain effect, sickness rate is down to 25%, and mortality rate is down to 10%.Owing to cannot thoroughly cure, finally this part chicken group eliminates.The pharmaceutical composition of the oral embodiment 1 of broiler of residue 1/2, within 4 days, sequela rate drops to 2%, and chickling stops dead, and jumpbogroup takes a turn for the better.
After raise again a collection of to 22 ages in days, occur same clinical symptoms, after being judged as coccidium infection, full group orally uses drug regimen and the using method of inventive embodiments 1, and within 4 days, sequela rate drops to 2%, and chickling stops dead.
Example 2:
Chicken farm, Mouping, Yantai, Sanhuang broiler
This is flat supports Sanhuang broiler 7000, raises to 31 ages in days and occurs dysentery, drawstring bloody stool just, inappetence, sickness rate 23%, mortality rate 7%.Clinical and laboratory diagnosis is coccidium infection, and the oral anticoccidial drug of broiler of 1/2 is as Maduramicin etc., and have certain effect, sickness rate is down to 19%, and mortality rate is down to 5%.The pharmaceutical composition of the oral embodiment 2 of chicken of residue 1/2, after 3 days, sickness rate is down to 2%, and dead stopping, this group of last health of chicken are delivered for sale.After raise again a collection of to 22 ages in days, occur same clinical symptoms, after being judged as coccidium infection, full group orally uses pharmaceutical composition and the using method of inventive embodiments 2, and within 3 days, sequela rate drops to 1%, and chickling stops dead, successful.
Example 3:
Chicken farm, Mouping, Yantai, AA broiler
This AA broiler 5000 of raising in cages, raises to 18 ages in days and occurs dysentery, drawstring bloody stool just, inappetence, sickness rate 13%, mortality rate 9%.Clinical and laboratory diagnosis is coccidium infection, and the oral anticoccidial drug of broiler of 1/3, as Maduramicin etc., has certain effect, sickness rate is down to 10%, and mortality rate is down to 7%, the medicine of the oral embodiment 3 of broiler of another 1/3, within 3 days, sequela rate is down to 2%, dead stopping.The medicine of the drug oral embodiment 4 of residue 1/3, sickness rate is down to 5%, and mortality rate is down to 3%.
After raise again a collection of, pharmaceutical composition and the prevention coccidiosis that full group orally uses inventive embodiments 3 is started in 13 ages in days, this chicken group feeding is supported to 45 ages in days and is delivered the generation finding no coccidiosis for sale, simultaneously for being contrast experiment, separately have 100 chickens to orally use the compositions of inventive embodiments 4, this chicken group feeding support to 45 ages in days deliver for sale also find no coccidiosis occur.
Medicine of the present invention has no side effect, easy to use.
Above-mentioned detailed description of the Chinese medicine composition of prevention and therapy Eimeria species being carried out with reference to embodiment; illustrative instead of determinate; several embodiments can be listed according to institute's limited range; therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (3)
1. the Chinese medicine composition of a prevention and therapy Eimeria species, it is characterized in that it is combined by weight by following medicine: Herba Artemisiae Annuae 8 ~ 12 parts, Herba Agrimoniae 1 ~ 3 part, Cacumen Platycladi 1 ~ 3 part, Fructus Crataegi 1 ~ 3 part, Rhizoma Coptidis 1 ~ 3 part, poplar bark lipoid is 10 ~ 40% of composition total weight, after water boiling concentration, granule is made in drying, and the final content of combination of Chinese medicine thing is controlled at 50 ~ 65% (percentage by weights).
2. the preparation method of a kind of Chinese medicine composition of prevention and therapy Eimeria species according to claim 1, it is characterized in that described 8 ~ 12 portions of Herba Artemisiae Annuaes, 1 ~ 3 part of Herba Agrimoniae, 1 ~ 3 portion of Cacumen Platycladi, 1 ~ 3 portion of Fructus Crataegi, after 1 ~ 3 part of Rhizoma Coptidis water drug-decocting concentrating liquid prepares extractum, granule is prepared in drying, medicinal residues crushed after being dried after extraction, poplar bark lipoid fully mixes with the form of evenly spraying and dried drug ground-slag, its addition is 10 ~ 40% of described compositions gross weight, after crossing 100 ~ 200 mesh sieves, the medicinal residues powder adding poplar bark lipoid is fully mixed according to weight ratio 1:1 with the granule prepared by water drug-decocting concentrating liquid, the final content of combination of Chinese medicine thing is controlled at 50 ~ 65% (percentage by weights).
3. the using method of Chinese medicine composition according to claim 1 or 2, add 10 ~ 40 grams of described compositionss according to per kilogram feedstuff in feedstuff when it is characterized in that using, mixed feeding 3 ~ 5 days is a course for the treatment of.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111000926A (en) * | 2019-12-31 | 2020-04-14 | 福建傲农生物科技集团股份有限公司 | Chinese herbal medicine composition for treating chicken coccidiosis and application |
| CN114468171A (en) * | 2020-10-23 | 2022-05-13 | 河北科星药业有限公司 | Feed additive for preventing and treating quail coccidiosis, preparation method and application |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129673A (en) * | 2007-08-17 | 2008-02-27 | 李培英 | Pure traditional Chinese medicine formulated product for preventing and treating coccidiosis |
| CN103784771A (en) * | 2011-06-29 | 2014-05-14 | 纽素乐必佳（天津）药业集团有限公司 | Traditional Chinese medicine composition has functions of anticoccidia, haemostasis and blood enriching, and antibiosis and antiphlogosis, and preparation method thereof |
-
2015
- 2015-05-12 CN CN201510237176.3A patent/CN104800317A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129673A (en) * | 2007-08-17 | 2008-02-27 | 李培英 | Pure traditional Chinese medicine formulated product for preventing and treating coccidiosis |
| CN103784771A (en) * | 2011-06-29 | 2014-05-14 | 纽素乐必佳（天津）药业集团有限公司 | Traditional Chinese medicine composition has functions of anticoccidia, haemostasis and blood enriching, and antibiosis and antiphlogosis, and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 孟新宇等: "NP- AC- 1中草药添加剂抗鸡E.acervulina和E.necatrix效力试验", 《中兽医医药杂志》 * |
| 张兴晓等: "类脂作为佐剂对新城疫灭活疫苗免疫效果的影响", 《中国家禽》 * |
| 秦枫等: "防治球虫病的常用中草药研究进展", 《中国医药导报》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111000926A (en) * | 2019-12-31 | 2020-04-14 | 福建傲农生物科技集团股份有限公司 | Chinese herbal medicine composition for treating chicken coccidiosis and application |
| CN114468171A (en) * | 2020-10-23 | 2022-05-13 | 河北科星药业有限公司 | Feed additive for preventing and treating quail coccidiosis, preparation method and application |
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