CN103784771A - Traditional Chinese medicine composition has functions of anticoccidia, haemostasis and blood enriching, and antibiosis and antiphlogosis, and preparation method thereof - Google Patents
Traditional Chinese medicine composition has functions of anticoccidia, haemostasis and blood enriching, and antibiosis and antiphlogosis, and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition has functions of anticoccidia, haemostasis and blood enriching, and antibiosis and antiphlogosis, and a preparation method thereof. The traditional Chinese medicine composition comprises the following components by weight: 9-11 parts of sweet wormwood, 5-7 parts of coptis, 1-2 parts of dichroa root, 1-2 parts of ash bark, 1-3 parts of hairyvein agrimony, 1-3 parts of pasque flower, 1-2 parts of mutmeg, 1-2 parts of Sophora alopecuroide, 1-3 parts of imperata rhizome and 1-2 parts of licorice. The preparation method comprises the following steps: employing petroleum ether and ethanol to respectively extract active ingredients of sweet wormwood and dichroa root, and performing water extraction by combining the active ingredient of sweet wormwood and dichroa root, performing vacuum concentration on a water extract, drying, adding an extract product while pelletizing, and drying the granule to obtain the particulate agent. The traditional Chinese medicine composition is based on a traditional Chinese medicine theory, combines a modern traditional Chinese medicine exploitation technology for developing and exploiting, the combination effect of traditional Chinese medicine prescription syndrome differentiation and treatment is kept, so that the particulate agent can be prepared; a modern science and technology means is used for quantitative and semi-quantitative detection of the active ingredients for most medicinal materials, the therapeutic effect is definite through clinic verification, and the traditional Chinese medicine composition is green veterinary drug with no nuisance and no public hazard.
Description
Technical field
The invention belongs to the field of Chinese medicines, especially a kind of anticoccidial, hemostasis are enriched blood, anti-inflammation Chinese medicine composition and preparation method thereof.
Background technology
In agricultural industry adjustment process, animal husbandry proportion increases gradually, and epidemic disease becomes the key factor of restriction animal husbandry development.China's veterinary drug production development is very slow, and the product of original creation does not almost have.At animal products, particularly in broiler outlet, developed country especially European Union, by epidemic disease and the residual technology barriers of having erected of medicine, claims again green barrier, although European Union to opening-up of china meat market, does not also have Chinese meat to go on the market in European Union so far.In order to solve the problems such as the disabling of some chemistry, teratogenesis, sight has been turned to Chinese herbal medicine by people.Domestic current veterinary drug kind is more, but Chinese herbal medicine for animals (comprising preparation) quality standard is qualitative rather than quantitative to effective ingredient always, and technique is coarse, and quality is unstable, and uncertain therapeutic efficacy is cut, and is unfavorable for the development of herbal medicine.
Summary of the invention
One of object of the present invention is to overcome the deficiencies in the prior art, provide a kind of anticoccidial, hemostasis enrich blood, anti-inflammation Chinese medicine composition.
Another object of the present invention is to provide that above-mentioned anticoccidial, hemostasis are enriched blood, the preparation method of anti-inflammation Chinese medicine composition.
The present invention solves its technical problem and is achieved through the following technical solutions:
A kind of anticoccidial, hemostasis are enriched blood, anti-inflammation Chinese medicine composition, and its constituent and parts by weight are respectively:
Herba Artemisiae Annuae 9-11 part, Rhizoma Coptidis 5-7 part, Radix Dichroae 1-2 part, Cortex Fraxini 1-2 part, Herba Agrimoniae 1-3 part, Radix Pulsatillae 1-3 part, Semen Myristicae 1-2 part, Herba Sophorae alopecuroidis 1-2 part, Rhizoma Imperatae 1-3 part, Radix Glycyrrhizae 1-2 part.
And a kind of anticoccidial, hemostasis are enriched blood, the preparation method of anti-inflammation Chinese medicine composition, the steps include:
(1) Herba Artemisiae Annuae is adopted to Petroleum ether extraction effective ingredient, reflux, extract, temperature is 60-90 ℃, obtains Herba Artemisiae Annuae petroleum ether extract, and adopts cold doubtful recovery petroleum ether, obtains Herba Artemisiae Annuae extracting solution stand-by, collects Herba Artemisiae Annuae medicinal residues;
(2) Radix Dichroae is adopted to dehydrated alcohol reflux, extract, effective ingredient, reflux temperature is 60-80 ℃, obtains Radix Dichroae ethanol extract, and adopts cold doubtful recovery ethanol, obtains Radix Dichroae extracting solution stand-by, collects Radix Dichroae medicinal residues;
(3) take respectively Rhizoma Coptidis, Cortex Fraxini, Herba Agrimoniae, the Radix Pulsatillae, Semen Myristicae, Herba Sophorae alopecuroidis, Rhizoma Imperatae, Radix Glycyrrhizae and mix, then add extracting the medicinal residues that Herba Artemisiae Annuae extracting solution and Radix Dichroae extracting solution produce, after stirring, carry out water extraction 2 times, merge the extracting solution after water extraction;
(4) by extracting solution concentrating under reduced pressure, dry, obtain dry extract;
(5) in dry extract, add stand-by Herba Artemisiae Annuae extracting solution and Radix Dichroae extracting solution, through granulation, dry, granulate, obtain the granule finished product of this Chinese medicine composition.
And the described water extraction method of step (3) is to adopt octuple water gaging to carry, 2 hours for the first time, water extraction 1 hour for the second time.
Advantage of the present invention and beneficial effect are:
1. this Chinese medicine composition, according to tcm theory, is developed in conjunction with modern Chinese medicine development technique, has retained the combined effect of Chinese medicinal formulae determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, can be made into granule; And use modern means of science and technology to the effective ingredient of most of medical material wherein carry out quantitatively, half-quantitative detection, through clinical verification determined curative effect, be the green veterinary drug of nuisanceless no drug residue.
2. this Chinese medicine composition is take monarch drug as main study subject, innovation extraction process, fully extract main effective ingredient, according to veterinary drug GMP standard, take Chinese veterinarian's experience as basis, adopt the herbal medicine of modern detection means and modern pharmaceutical equipment development and popularization good effect, nuisanceless, noresidue, taking convenience.
3. this Chinese medicine composition is made granule with the main component of monarch drug, improves quality standard, improves technique, strengthen quality control process, screening authentic medicinal herbs, stabilized product quality, with low cost, anticoccidial, hemostasis are enriched blood, anti-inflammation good effect, have stronger product market competition ability.
The specific embodiment
Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
Embodiment 1:
A kind of anticoccidial, hemostasis are enriched blood, anti-inflammation Chinese medicine composition, and its constituent and weight thereof are respectively:
Herba Artemisiae Annuae 500g, Rhizoma Coptidis 300g, Radix Dichroae 50g, Fructus Gardeniae 50g, Radix Rehmanniae Preparata 100g, Rhizoma Fagopyri Dibotryis 100g Radix Cirsii Japonici 50g, Radix Paeoniae Alba 50g, Cortex Phellodendri 100g, Radix Glycyrrhizae 50g.
Anticoccidial, hemostasis are enriched blood, a preparation method for anti-inflammation Chinese medicine composition, and the step of preparation method is:
(1) Herba Artemisiae Annuae is adopted to Petroleum ether extraction effective ingredient, reflux, extract, temperature is 80 ℃, obtains Herba Artemisiae Annuae petroleum ether extract, and adopts cold doubtful recovery petroleum ether, obtains Herba Artemisiae Annuae extracting solution stand-by, collects Herba Artemisiae Annuae medicinal residues;
(2) Radix Dichroae is adopted to dehydrated alcohol reflux, extract, effective ingredient, reflux, extract, temperature is 70 ℃ and obtains Radix Dichroae ethanol extract, and adopts cold doubtful recovery ethanol, obtains Radix Dichroae extracting solution stand-by, collects Radix Dichroae medicinal residues;
(3) take respectively Rhizoma Coptidis, Cortex Fraxini, Herba Agrimoniae, the Radix Pulsatillae, Semen Myristicae, Herba Sophorae alopecuroidis, Rhizoma Imperatae, Radix Glycyrrhizae and mix, then adding extracting the medicinal residues that careless extracting solution and Radix Dichroae extracting solution are produced, after stirring, carrying out water extraction 2 times; Water extraction adopts octuple water gaging to extract 2 hours for the first time, and water extraction 1 hour for the second time merges the extracting solution after water extraction;
(4) by extracting solution concentrating under reduced pressure, dry, obtain dry extract;
(5) in dry extract, add stand-by Herba Artemisiae Annuae extracting solution and Radix Dichroae extracting solution, granulate, dry, granulate, obtain the granule finished product of this Chinese medicine composition.
In the present invention, the effective ingredient of Herba Artemisiae Annuae---arteannuin >=0.6% (finished product gross weight), the effective ingredient of Radix Dichroae---halofuginone hydrobromide >=0.4mg/g (finished product gross weight).
Embodiment 2:
A kind of anticoccidial, hemostasis are enriched blood, anti-inflammation Chinese medicine composition, and its constituent and weight thereof are respectively:
Herba Artemisiae Annuae 100g, Rhizoma Coptidis 50g, Radix Dichroae 10g, Cortex Fraxini 10g, Herba Agrimoniae 20g, Radix Pulsatillae 20g, Semen Myristicae 10g, Herba Sophorae alopecuroidis 10g, Rhizoma Imperatae 20g, Radix Glycyrrhizae 10g.
Its preparation method is same as embodiment 1.
Preparation stability test
。
Claims (3)
- Anticoccidial, hemostasis enrich blood, an anti-inflammation Chinese medicine composition, it is characterized in that: its constituent and parts by weight are respectively:Herba Artemisiae Annuae 9-11 part, Rhizoma Coptidis 5-7 part, Radix Dichroae 1-2 part, Cortex Fraxini 1-2 part, Herba Agrimoniae 1-3 part, Radix Pulsatillae 1-3 part, Semen Myristicae 1-2 part, Herba Sophorae alopecuroidis 1-2 part, Rhizoma Imperatae 1-3 part, Radix Glycyrrhizae 1-2 part.
- 2. prepare that anticoccidial as claimed in claim 1, hemostasis are enriched blood, the method for anti-inflammation Chinese medicine composition, it is characterized in that: the steps include:(1) Herba Artemisiae Annuae is adopted to Petroleum ether extraction effective ingredient, reflux, extract, temperature is 60-90 ℃, obtains Herba Artemisiae Annuae petroleum ether extract, and adopts cold doubtful recovery petroleum ether, obtains Herba Artemisiae Annuae extracting solution stand-by, collects Herba Artemisiae Annuae medicinal residues;(2) Radix Dichroae is adopted to dehydrated alcohol reflux, extract, effective ingredient, reflux temperature is 60-80 ℃, obtains Radix Dichroae ethanol extract, and adopts cold doubtful recovery ethanol, obtains Radix Dichroae extracting solution stand-by, collects Radix Dichroae medicinal residues;(3) take respectively Rhizoma Coptidis, Cortex Fraxini, Herba Agrimoniae, the Radix Pulsatillae, Semen Myristicae, Herba Sophorae alopecuroidis, Rhizoma Imperatae, Radix Glycyrrhizae and mix, then add extracting the medicinal residues that Herba Artemisiae Annuae extracting solution and Radix Dichroae extracting solution produce, after stirring, carry out water extraction 2 times, merge the extracting solution after water extraction;(4) by extracting solution concentrating under reduced pressure, dry, obtain dry extract;(5) in dry extract, add stand-by Herba Artemisiae Annuae extracting solution and Radix Dichroae extracting solution, through granulation, dry, granulate, obtain the granule finished product of this Chinese medicine composition.
- Anticoccidial according to claim 2, hemostasis enrich blood, the preparation method of anti-inflammation Chinese medicine composition, it is characterized in that: the described water extraction method of step (3) is for adopting octuple water gaging to carry, 2 hours for the first time, water extraction 1 hour for the second time.
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| CN201110178395.0A CN103784771A (en) | 2011-06-29 | 2011-06-29 | Traditional Chinese medicine composition has functions of anticoccidia, haemostasis and blood enriching, and antibiosis and antiphlogosis, and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104288671A (en) * | 2014-09-10 | 2015-01-21 | 青岛华仁技术孵化器有限公司 | Medicine for preventing rabbit coccidiosis |
| CN104800317A (en) * | 2015-05-12 | 2015-07-29 | 鲁东大学 | Chinese medicinal composition for preventing and treating chicken coccidiosis and preparation method |
| CN105395930A (en) * | 2015-11-30 | 2016-03-16 | 梁苡玮 | Antisepsis and anti-inflammation drug for external use |
| CN109364230A (en) * | 2018-12-18 | 2019-02-22 | 丹东瑞丰动物药业有限责任公司 | A kind of Chinese medicine and preparation method thereof for treating chicken coccidiasis |
-
2011
- 2011-06-29 CN CN201110178395.0A patent/CN103784771A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104288671A (en) * | 2014-09-10 | 2015-01-21 | 青岛华仁技术孵化器有限公司 | Medicine for preventing rabbit coccidiosis |
| CN104800317A (en) * | 2015-05-12 | 2015-07-29 | 鲁东大学 | Chinese medicinal composition for preventing and treating chicken coccidiosis and preparation method |
| CN105395930A (en) * | 2015-11-30 | 2016-03-16 | 梁苡玮 | Antisepsis and anti-inflammation drug for external use |
| CN109364230A (en) * | 2018-12-18 | 2019-02-22 | 丹东瑞丰动物药业有限责任公司 | A kind of Chinese medicine and preparation method thereof for treating chicken coccidiasis |
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Application publication date: 20140514 |