CN106421489A - Preparing method for blood glucose reducing substitute tea prepared by adopting edible plants as components - Google Patents
Preparing method for blood glucose reducing substitute tea prepared by adopting edible plants as components Download PDFInfo
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- CN106421489A CN106421489A CN201611041109.5A CN201611041109A CN106421489A CN 106421489 A CN106421489 A CN 106421489A CN 201611041109 A CN201611041109 A CN 201611041109A CN 106421489 A CN106421489 A CN 106421489A
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- fructus
- rhizoma
- rhizoma polygonati
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/34—Tea substitutes, e.g. matè; Extracts or infusions thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The invention discloses a preparing method for blood glucose reducing substitute tea prepared by adopting edible plants as components. The substitute tea is prepared from 5-15 g of rhizoma polygonati odorati, 5-15 g of fructus mume, 7.5-22.5 g of rhizoma dioscoreae, 10-30 g of fructus canarli, 7.5-22.5 g of semen zizyphi spinosae, 7.5-22.5 g of fructus lycii, 7.5-22.5 g of mulberry, 10-30 g of rhizoma polygonati, 10-30 g of radix puerariae and 5-15 g of rhizoma imperatae. The tea is prepared from particles prepared by adopting a mixed smashing method or a water extraction and alcohol sedimentation technique or an alcohol extraction and water sedimentation method. The blood glucose reducing substitute tea is convenient to carry and drink good in mouthfeel and readily accepted by people; the tea contains no food additives, hormones and harmful substances and is suitable for being drunk by people with relatively high blood glucose for a long time.
Description
Technical field
The present invention relates to the beverage that a kind of similar Folium Camelliae sinensis brew, especially a kind of made as composition using food plant
The preparation method of blood sugar lowering alternative tea.
Background technology
Diabetes are a kind of common metabolism endocrinopathyes, and World Health Organization (WHO) is classified as one of ten big difficult disease.
Sickness rate is high, and has the trend rising year by year;According to《The New York Times》Report, a current research shows, the diabetes of China
Prevalence occupy first place in the world, but also is continuing to deteriorate.It is published in《JAMA》Aforementioned current research then table
Bright, the diabetes prevalence of China is just beyond the U.S.:11.6% Chinese adult suffers from this disease, and the U.S. is 11.3%.
1980, the diabetes prevalence of China was less than 1%.Diabetes mellitus in China subject population reaches 1.14 hundred million, estimates than 2007
Numeral rises 22,000,000 that is to say, that the diabeticss in the whole world about 1/3rd are all in China.More allow people worried,
This research is tested to nearly 9.9 ten thousand people, finds that the people's blood glucose having half has reached " prediabeteses " level.Research
Point out:" China is currently one of Asia diabetes prevalence highest country, is also that the absolute number of diabeticss is the most in the world
Many countries ".
Adopting the leaf of plant of integration of edible and medicinal herbs, flower, fruit, rhizome etc. to be raw material alternative tea more, assorted by a certain percentage plus
The product that work becomes, and pass through pouch-packaged, it is eaten for a long time and have no toxic side effect, and because concentration is low, zest is little, in good taste, it is fall
The optimum selection of blood glucose.This at present the taste of modern is more met as the alternative tea product of effective ingredient using food plant
And living habit, therefore there is very wide market prospect, people have tight demand to hypoglycemic alternative tea product.
Up to now, also do not find any report about the alternative tea composition of the present invention and preparation method thereof.The present invention
People, through repeatedly studying, have found alternative tea of more preferable blood sugar decreasing effect and preparation method thereof finally, thus completing this
Bright.
Content of the invention
The object of the invention is exactly to provide a kind of generation having more preferable blood sugar decreasing effect made using food plant as composition
Preparation method with tea.
The present invention is a kind of blood sugar lowering alternative tea made as composition using food plant, wherein said food plant
It is made up of following raw materials according:Rhizoma Polygonati Odorati, Fructus Mume, Rhizoma Dioscoreae, Fructus Canarii, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Mori, Rhizoma Polygonati, Radix Puerariae, Rhizoma Imperatae.
It has selected Rhizoma Polygonati Odorati, Fructus Mume, Rhizoma Dioscoreae, Fructus Canarii, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Mori, Rhizoma Polygonati, Radix Puerariae, Rhizoma Imperatae are combined
As raw material, wherein(1)Rhizoma Polygonati Odorati is the drying of liliaceous plant Rhizoma Polygonati Odorati Polygonatum odoratum (Mill.) Druce
Rhizome.There is nourishing YIN to relieve dryness, effect of promoting the production of body fluid to quench thirst.For lung stomach impairment of yin, cough caused by dryness-heat, dry throat and mouth, Heat Diabetes.(2)
Fructus Mume be rose department plant plum Prunus mume (Sieh.) Sieb.et Zucc. almost ripe fruit is dried.Have and astringe the lung,
Astringing intestine to stop diarrhea, promotes the production of body fluid, effect of relieving colic caused by ascaris.For chronic cough of deficiency lung, chronic dysentery laxation, deficiency-heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache, ascariasis of biliary tract.
(3)Rhizoma Dioscoreae is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae Dioscorea opposita Thunb..There is spleen reinforcing nourishing the stomach, promote the production of body fluid
Lung benefiting, effect of the kidney invigorating arresting seminal emission.For spleen eating less, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat disappears
Yearningly.(4)Fructus Canarii is the dry mature fruit of olive subject plant Fructus Canarii albi Canarium album Raeusch..There is heat clearing away, profit
Pharynx, promotes the production of body fluid, effect of removing toxic substances.For laryngopharynx swelling and pain, cough, excessive thirst, fish and crab poisoning.(5)Semen Ziziphi Spinosae is rhamnaceae plant wild jujube
The dry mature seed of Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H.F.Chou.Have
Tonifying liver, mind calming, arresting sweating, the effect promoted the production of body fluid.For restlessness of asrhenia type and insomnia, horrified to much dream, body void hidrosis, injury thirst.(6)Fructus Lycii is eggplant
The dry mature fruit of section plant lycium barbarum Lycium barbarum L..There is nourishing the liver and kidney, effect of replenishing vital essence to improve eyesight.With
In consumption consumptive loss, soreness of waist and knee joint, vertigo and tinnitus, Heat Diabetes, blood deficiency and yellow complexion, blurred vision.(7)Fructus Mori is moraceae plants mulberry
Morus alba L. is dried fruit ear.There is YIN nourishing of enriching blood, effect of fluid dryness.For vertigo and tinnitus, palpitation and insomnia, palpus
Send out early white, injury thirst, Heat Diabetes, blood deficiency and constipation.(8)Rhizoma Polygonati is liliaceous plant P. kingianum Polygonatum
Kingianum Coll.et Hemsl., Rhizoma Polygonati Polygona-tum sibiricum Red. or Polygonatum cyrtonema Hua Polygonatum
The dry rhizome of cyrtonema Hua.There is boosting qi and nourishing yin, spleen invigorating, lung moistening, effect of kidney tonifying.For weakness of the spleen and stomach, body is tired
Weak, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, Heat Diabetes.(9)Radix Puerariae is legume pueraria lobata Pueraria lobata
(Willd.) dry root of Ohwi or Radix Puerariae rattan Pueraria thomsoniiBenth..There is expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash,
Effect of Shengyang Zhixie.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, have loose bowels;Hypertension
Neck pain.(10)Rhizoma Imperatae is grass Herba Imperatae Imperata cylindrica Beauv. var. major
(Nees) dry rhizome of C.E.Hubb..There is cooling blood for hemostasis, effect of clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, urine
Blood, pyreticosis polydipsia, jaundice, edema, puckery pain of heat gonorrhea;Acute nephritis edema.These food plants are applied in combination so that each raw material
Effect produces synergism, thus having hypoglycemic effect.
In alternative tea of the present invention, the consumption of food plant is also to be groped in a large number to summarize to draw through inventor, each former
Material consumption is all to have better effects in following concrete weight ranges:Rhizoma Polygonati Odorati 5~15g, Fructus Mume 5~15g, Rhizoma Dioscoreae 7.5~
22.5g, Fructus Canarii 10~30g, Semen Ziziphi Spinosae 7.5~22.5g, Fructus Lycii 7.5~22.5g, Fructus Mori 7.5~22.5g, Rhizoma Polygonati 10~30g,
Radix Puerariae 10~30g, Rhizoma Imperatae 5~15g.
It is preferably:Rhizoma Polygonati Odorati 8~12g, Fructus Mume 8~12g, Rhizoma Dioscoreae 12~18g, Fructus Canarii 16~24g, Semen Ziziphi Spinosae 12~18g, Chinese holly
Qi 12~18g, Fructus Mori 12~18g, Rhizoma Polygonati 16~24g, Radix Puerariae 16~24g, Rhizoma Imperatae 8~12g.
More preferably:Rhizoma Polygonati Odorati 10g, Fructus Mume 10g, Rhizoma Dioscoreae 15g, Fructus Canarii 20g, Semen Ziziphi Spinosae 15g, Fructus Lycii 15g, Fructus Mori
15g, Rhizoma Polygonati 20g, Radix Puerariae 20g, Rhizoma Imperatae 10g.
In alternative tea of the present invention, the raw material of above-mentioned consumption can directly be weighed by the preparation of edible plants by weight, adopts
Make granule after method after co-grinding to be obtained;The raw material of above-mentioned consumption can also be adopted after decoction and alcohol sedimentation technique or ethanol extract from water precipitation
Make granule to be obtained.
The packing specification of alternative tea of the present invention, eating method and amount are:1)Edible plants raw material is using directly pressing
Weight weighs, co-grinding is made, and often packed 5g, brews 3~5min with boiling water, one time 1 bag, 1~2 time on the one.2)Edible
Made using decoction and alcohol sedimentation technique or ethanol extract from water precipitation with plant material, often packed 2g, is brewed with boiling water, one time 1 bag, one day 1
~2 times.
Alternative tea of the present invention carries, easy to use, in good taste, is easily accepted;Using edible plants raw material composition,
Without any food additive, hormone and harmful substance it is adaptable to high blood glucose person is eaten for a long time.
【Specific embodiment】
With reference to embodiment, further detailed description is done to alternative tea of the present invention, but the embodiment of alternative tea of the present invention is not
It is limited to this.
【Embodiment 1】
Weigh Rhizoma Polygonati Odorati 10g, Fructus Mume 10g, Rhizoma Dioscoreae 15g, Fructus Canarii 20g, Semen Ziziphi Spinosae 15g, Fructus Lycii 15g, Fructus Mori 15g, Rhizoma Polygonati 20g, Pueraria lobota
Root 20g, Rhizoma Imperatae 10g, after mixing, comminution by gas stream becomes fine powder, fluidized bed spray granulation, and 60 DEG C ± 5 DEG C are dried 3h ± 0.5h, whole
Grain, prepared particle diameter, in the granule of 0.5mm size, mixes, is packaged into the alternative tea of often packed 5g with particles packing machine.
【Embodiment 2】
Weigh Rhizoma Polygonati Odorati 8g, Fructus Mume 8g, Rhizoma Dioscoreae 12g, Fructus Canarii 16g, Semen Ziziphi Spinosae 12g, Fructus Lycii 12g, Fructus Mori 12g, Rhizoma Polygonati 16g, Radix Puerariae
16g, Rhizoma Imperatae 8g, after mixing, mechanical activation comminution becomes fine powder, sprays water to forming loose granular, extruder grain, 60 DEG C ± 5 DEG C are dried 3h
± 0.5h, granulate, prepared particle diameter, in the granule of 1mm size, mixes, is packaged into the alternative tea of often packed 5g with particles packing machine.
【Embodiment 3】
Weigh Rhizoma Polygonati Odorati 12g, Fructus Mume 12g, Rhizoma Dioscoreae 18g, Fructus Canarii 24g, Semen Ziziphi Spinosae 18g, Fructus Lycii 18g, Fructus Mori 18g, Rhizoma Polygonati 24g, Pueraria lobota
Root 24g, Rhizoma Imperatae 12g, after mixing, mechanical activation comminution becomes coarse powder, makees solvent with 70% ethanol, dipping slowly percolation after 48 hours, receives
Collection percolate, heating concentrates reclaims ethanol simultaneously, is concentrated into relative density 1.05~1.10(25℃), stand 24 hours, take
Clear liquid, spray-drying process, granulate, prepared particle diameter, in the granule of 1mm size, mixes, is packaged into particles packing machine often packed
The alternative tea of 2g.
【Embodiment 4】
Weigh Rhizoma Polygonati Odorati 5g, Fructus Mume 5g, Rhizoma Dioscoreae 7.5g, Fructus Canarii 10g, Semen Ziziphi Spinosae 7.5g, Fructus Lycii 7.5g, Fructus Mori 7.5g, Rhizoma Polygonati 10g,
Radix Puerariae 10g, Rhizoma Imperatae 5g, after mixing, mechanical activation comminution becomes coarse powder, with water boiling and extraction 2 times, extracts 2h for the first time, collects and extract
Liquid, residue adds water to cook extraction 1 hour, collects extracting solution, merges 2 extracting solution heating and concentrates, is concentrated into relative density 1.05
~1.10(25℃), spray-drying process, granulate, prepared particle diameter, in the granule of 2mm size, mixes, is packed with particles packing machine
Become the alternative tea of often packed 2g.
【Embodiment 5】
Weigh Rhizoma Polygonati Odorati 15g, Fructus Mume 15g, Rhizoma Dioscoreae 22.5g, Fructus Canarii 30g, Semen Ziziphi Spinosae 22.5g, Fructus Lycii 22.5g, Fructus Mori 22.5g, Huang
Smart 30g, Radix Puerariae 30g, Rhizoma Imperatae 15g, after mixing, mechanical activation comminution becomes coarse powder, makees solvent with 65% ethanol, heating and refluxing extraction 2 times,
Extract 2h for the first time, collect extracting solution, residue adds 65% alcohol reflux 1 hour, collect extracting solution, merge 2 extracting solution and add
Heat concentrates and reclaims ethanol simultaneously, is concentrated into relative density 1.05~1.10(25℃), spray-drying process, granulate, prepared particle diameter
In the granule of 2mm size, mix, be packaged into the alternative tea of often packed 2g with particles packing machine.
【Embodiment 6】
Weigh Rhizoma Polygonati Odorati 9g, Fructus Mume 9g, Rhizoma Dioscoreae 13.5g, Fructus Canarii 18g, Semen Ziziphi Spinosae 13.5g, Fructus Lycii 13.5g, Fructus Mori 13.5g, Rhizoma Polygonati
18g, Radix Puerariae 18g, Rhizoma Imperatae 9g, after mixing, mechanical activation comminution becomes coarse powder, with water boiling and extraction 2 times, extracts 2h for the first time, collection carries
Take liquid, residue adds water to cook extraction 1 hour, collect extracting solution, merge 2 extracting solution heating and concentrate, be concentrated into relative density
1.20~1.30(25℃), plus 95% ethanol stirring, reach 60% to concentration of alcohol, stand 12 hours, take supernatant, heating is dense
Contracting reclaims ethanol simultaneously, is concentrated into relative density 1.05~1.10(25℃), spray-drying process, granulate, prepared particle diameter is in 1mm
The granule of size, mixes, is packaged into the alternative tea of often packed 2g with particles packing machine.
Application Example, in order to verify blood sugar lowering alternative tea effect of the present invention, will be produced to embodiment 1 gained below
Product carry out the pharmacodynamic experiment research on mouse blood sugar impact for the impact to spontaneous hyperglycemia and serum insulin.
Method:NOD mice, after empty stomach 6h, measures blood glucose, selects the animal 50 that blood glucose value is higher than 11.1mmol/L, with
Machine is divided into 5 groups, and gavage gives following products respectively:Matched group(Distilled water);Glyburide group (25mg/kg);The embodiment of the present invention 1
By basic, normal, high dosage group (2,4,8mg/kg).Continuous giving eats 14d, measures animal blood glucose value with blood glucose meter, uses radioimmunology
Measure serum insulin, the results are shown in Table 1,2.
The impact to spontaneous hyperglycemia mouse blood sugar for table 1 embodiment of the present invention 1(X scholar s)
Blood glucose value before Group Animals number dosage (g/kg) food(mmol/L)Blood glucose value after food(mmol/L)
Model control group 10 12.13 ± 8.38 12.46 ± 4.65
Glyburide 10 25mg 12.17 ± 4.58 10.14 ± 2.18**
Low dose group 10 2 12.63 ± 5.72 12.13 ± 1.28*
Middle dose group 10 4 12.54 ± 3.76 11.59 ± 1.56**
High dose group 10 8 12.45 ± 1.18 10.87 ± 1.43**
Note:Compare with model control group*P<0.05,**P<0.0l.
The impact to spontaneous hyperglycemia mice serum insulin for table 2 embodiment of the present invention 1(x±s)
Group Animals number dosage (g/kg) serum insulin(MIU/L)
Model control group 10 14.23 ± 2.43
Glyburide 10 25mg 26.89 ± 3.76**
Low dose group 10 2 15.68 ± 3.37
Middle dose group 10 4 17.29 ± 1.24*
High dose group 10 8 19.67 ± 2.78**
Note:Compare with model control group*P<0.05,**P<0.0l.
Experimental result:The basic, normal, high dosage group of the NOD Mouse oral embodiment of the present invention 1, can reduce blood glucose and increasing serum
Insulin.
Result above shows, alternative tea of the present invention has obvious hypoglycemic activity.
Claims (3)
1. a kind of preparation method of the blood sugar lowering alternative tea made as composition using food plant is it is characterised in that be by following
Concrete weight pressed by raw material:Rhizoma Polygonati Odorati 5~15g, Fructus Mume 5~15g, Rhizoma Dioscoreae 7.5~22.5g, Fructus Canarii 10~30g, Semen Ziziphi Spinosae 7.5~
22.5g, Fructus Lycii 7.5~22.5g, Fructus Mori 7.5~22.5g, Rhizoma Polygonati 10~30g, Radix Puerariae 10~30g, Rhizoma Imperatae 5~15g, adopt
Co-grinding method or decoction and alcohol sedimentation technique or ethanol extract from water precipitation are made particle preparation and are formed.
2. according to claim 1 blood sugar lowering alternative tea preparation method it is characterised in that:It is preferred that concrete weight pressed by each raw material
For:Rhizoma Polygonati Odorati 8~12g, Fructus Mume 8~12g, Rhizoma Dioscoreae 12~18g, Fructus Canarii 16~24g, Semen Ziziphi Spinosae 12~18g, Fructus Lycii 12~18g, Mulberry
Mulberry 12~18g, Rhizoma Polygonati 16~24g, Radix Puerariae 16~24g, Rhizoma Imperatae 8~12g.
3. according to claim 2 blood sugar lowering alternative tea preparation method it is characterised in that:It is preferred that concrete weight pressed by each raw material
For:Rhizoma Polygonati Odorati 10g, Fructus Mume 10g, Rhizoma Dioscoreae 15g, Fructus Canarii 20g, Semen Ziziphi Spinosae 15g, Fructus Lycii 15g, Fructus Mori 15g, Rhizoma Polygonati 20g, Radix Puerariae 20g,
Rhizoma Imperatae 10g.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108041579A (en) * | 2017-12-07 | 2018-05-18 | 云南瑞药金方现代中药有限公司 | A kind of instant hypoglycemic meal and preparation method thereof |
CN112544844A (en) * | 2020-12-09 | 2021-03-26 | 新化县绿源农林科技有限公司 | Rhizoma polygonati solid beverage with blood glucose reducing effect and preparation method thereof |
Citations (2)
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CN104855650A (en) * | 2015-06-01 | 2015-08-26 | 西宁志培知识产权咨询有限公司 | Preparation method of hypoglycemic substitutional tea prepared by food plants serving as constituents |
CN104938728A (en) * | 2015-07-20 | 2015-09-30 | 青海省通天河藏药制药有限责任公司 | Preparation method of substitutional tea for reducing blood glucose |
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Patent Citations (2)
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CN104855650A (en) * | 2015-06-01 | 2015-08-26 | 西宁志培知识产权咨询有限公司 | Preparation method of hypoglycemic substitutional tea prepared by food plants serving as constituents |
CN104938728A (en) * | 2015-07-20 | 2015-09-30 | 青海省通天河藏药制药有限责任公司 | Preparation method of substitutional tea for reducing blood glucose |
Non-Patent Citations (1)
Title |
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杨玺编: "《糖尿病个体化用药与调养》", 30 April 2015, 金盾出版社 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108041579A (en) * | 2017-12-07 | 2018-05-18 | 云南瑞药金方现代中药有限公司 | A kind of instant hypoglycemic meal and preparation method thereof |
CN112544844A (en) * | 2020-12-09 | 2021-03-26 | 新化县绿源农林科技有限公司 | Rhizoma polygonati solid beverage with blood glucose reducing effect and preparation method thereof |
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