CN106417920A - Traditional Chinese medicine feed additive capable of replacing antibiotics and preparation method thereof - Google Patents
Traditional Chinese medicine feed additive capable of replacing antibiotics and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of research and development of feed additives and particularly relates to a traditional Chinese medicine feed additive capable of replacing antibiotics and a preparation method thereof. The traditional Chinese medicine feed additive capable of replacing antibiotics is prepared from the following components in parts by weight: 2-4 parts of ganoderma lucidum polysaccharide, 3-8 parts of Chinese yam powder, 1-4 parts of picrasma quassioides, 2-5 parts of Chinese mahonia stem, 1-3 parts of bitter almond kernels, 3-4 parts of herba corydalis bungeanae, 2-5 parts of schizonepeta spike, 2-3 parts of rabdosia lophanthide, 1-2 parts of centella asiatica, 2-5 parts of fructus forsythiae, 2-4 parts of radix isatidis, 2-3 parts of radix rosa laevigata, 2-5 parts of nutrient enrichment flour and 30-50 parts of a carrier. The traditional Chinese medicine feed additive capable of replacing antibiotics has the effects of clearing heat and removing toxicity, strengthening the spleen and nourishing the kidneys and promoting digestion, also has the effect of obviously enhancing the antibacterial activity, and is suitable for replacing antibiotics as animal feed additives.
Description
Technical field
The invention belongs to feed addictive research and development technology field, add particularly to a kind of Chinese medicine fodder of alternative antibiotic
Plus agent and preparation method thereof.
Background technology
The feed addictive of existing disease-resistant growth-promoting is mainly antibiotic and chemicals additive.Long-Time Service antibiosis
Element and chemical drugs species additive side effect are very big, and pathogenic microorganism on the one hand can be caused to develop immunity to drugs, and reduce Animal diseases
Prevention effect；On the other hand medicament residue can be produced in meat, egg, milk and environment, thus seriously threatening health.For
This, the regulation that should be used as to limit and be phased out or disable to antibiotic and chemicals additive for the world many countries.
Chinese herbal medicine immunity substance mass-energy strengthens human body immune function, improves animal resisting stress, resistance against diseases, improves animal
Production performance, has the advantages that noresidue, is not likely to produce drug resistance, is the focus of animal nutrition research in recent years.According to literary composition
Offer report, the Chinese herbal medicine currently used for raw materials of feed additives has kind more than 200, and some patents of invention also disclose that various Chinese herbal medicines
The formula of feed addictive, the effect of various formulas and cost are also had nothing in common with each other, and also thousand change ten thousand of the preparation method of Chinese herbal medicine
Change, majority is no longer added using directly pulverizing, because direct comminuting method dosage and active constituent content are unstable.
CN103005210 B discloses a kind of pig feed additive of alternative antibiotic, by Divine Comedy, Radix Angelicae Sinensis, the Radix Astragali, mountain
Short, bristly hair or beard, Radix Codonopsis, citric acid, lactic acid, be coated phosphoric acid, Tiny ecosystem system, yeast cell wall polysaccharide composition.CN103947907 B discloses
The pig immunity enhancement type feed addictive of another kind of alternative antibiotic, by lotus leaf polysaccharide, Fructus Choerospondiatis extract, angelica powder, purple
Perilla leaf powder, Chinese holly powder, Longtube Ground Ivy Herb powder, probiotics, allicin, B B-complex, composite mineral matter and carrier composition.Group
Fang Duowei enriching yin and nourishing kidney nourishing the stomach Chinese medicine, or the Chinese medicine of polysaccharide enhancing nonspecific immunity function, using effect and range of application are equal
By larger restriction.So the new prescription of exploitation is very necessary.
The present invention is exactly on this basis, proposes a kind of Chinese herbal feed additive for alternative antibiotic, it has
Efficiently, have no toxic side effect, safe, noresidue many advantages, such as, and wide material sources, low cost, the immune system to animal
Carry out across-the-board regulation, improve its resistance against diseases and immunity function.
The information being disclosed in this background section is merely intended to increase the understanding of the general background to the present invention, and should not
Recognize when being considered or imply in any form that this information structure has been the prior art well known to persons skilled in the art.
Content of the invention
For deficiency above-mentioned present in prior art, the present invention provides a kind of Chinese medicine fodder of alternative antibiotic to add
Agent and preparation method thereof, this Chinese herbal feed additive reasonable recipe, preparation are simple, effect substantially, have no toxic side effect, have no drug resistance
And medicament residue, can effective substitute antibiotics.
To achieve these goals, the present invention is to employ the following technical solutions realization：
A kind of Chinese herbal feed additive of alternative antibiotic, by being made up of following components by weight：GL-B 2-4
Part, common yam rhizome powder 3-8 part, quassia 1-4 part, leatherleaf mahonia 2-5 part, semen armeniacae amarae 1-3 part, corydlis bungeana 3-4 part, ching-chieh 2-5 part, small stream are yellow
Careless 2-3 part, centella 1-2 part, capsule of weeping forsythia 2-5 part, Radix Isatidis 2-4 part, cherokee rose root 2-3 part, reinforced nutritious powder 2-5 part and carrier
30-50 part.
Preferably, the preparation method of described GL-B is：Glossy ganoderma be dry, pulverize 60 mesh sieves, obtain glossy ganoderma powder；
Using water extraction solvent extraction water extraction, reduced pressure concentration, obtain lucidum concentrating liquid；It is subsequently adding 95% ethanol of 6 times of volumes, in 23-
Soak 20h at 28 DEG C, soak and carry out filtration treatment after terminating, filter residue and drying obtains pretreated glossy ganoderma powder；Will be pretreated
Glossy ganoderma powder press solid-liquid ratio 1：5-8 adds distilled water, and using ultrasonic extraction 30-40 minute, ultrasonic power is 140-190W, ultrasonic
Temperature 65-75 DEG C, is filtered after ultrasonic end, is taken filtrate；Filtrate is carried out centrifugal treating, centrifuge RPMs 4600r/min, from
Heart time 5min, takes supernatant to carry out freeze-drying, pulverized 60 mesh sieves, and obtained final product GL-B.
Preferably, the preparation method of described common yam rhizome powder is：By the Huaihe River mountain removal of impurities peeling of fresh collection, at 60-75 DEG C
Under dry, pulverize 50 mesh sieves, obtain Huaihe River mountain meal；By Huaihe River mountain meal and complex enzyme in mass ratio 50:3 mixings, then press solid-liquid ratio
1:5 addition distilled water, at 55-70 DEG C, temperature boils 60-90min, and temperature is directly dried process after boiling end, pulverizes 80 mesh
Sieve, obtains final product common yam rhizome powder.
Preferably, described complex enzyme is by amylase, 1,4 beta-glucanase, zytase, cellulase in mass ratio 4：2：
1：1 composition.
Preferably, the preparation method of described quassia is：Quassia be dry, pulverize 80 mesh sieves；Described leatherleaf mahonia
Preparation method be：Leatherleaf mahonia be dry, pulverize 80 mesh sieves；Described amygdalate preparation method is：Semen armeniacae amarae is done
Dry, pulverized 80 mesh sieves；The preparation method of described corydlis bungeana is：Corydlis bungeana be dry, pulverize 80 mesh sieves；Described
The preparation method of ching-chieh is：Ching-chieh be dry, pulverize 80 mesh sieves；The preparation method of described rabdosia lophanthide is：By small stream
Yellow grass dry, pulverize 80 mesh sieves；The preparation method of described centella is：Centella be dry, pulverize 80 mesh sieves is
Can；The preparation method of the described capsule of weeping forsythia is：The capsule of weeping forsythia be dry, pulverize 80 mesh sieves；The preparation method of described Radix Isatidis is：Will
Radix Isatidis dry, pulverize 80 mesh sieves；The preparation method of described cherokee rose root is：Cherokee rose root be dry, pulverize 80 mesh sieves
?.
Preferably, described reinforced nutritious powder is by wheat germ powder, beer yeast powder and protein powder 3-5 in mass ratio:
4-5:1-3 forms.
Preferably, described carrier is dehulled soybean meal powder and high lactose whey powder, dehulled soybean meal powder and high lactose whey
Powder in mass ratio 6：2,60 mesh sieves pulverized in advance by dehulled soybean meal powder and high lactose whey powder.
Compared with prior art, the present invention has the advantages that：
(1) Chinese herbal feed additive of the alternative antibiotic of the present invention, has clearing heat and detoxicating, invigorating the spleen and supports kidney, promotees digestion
Effect, antibacterial activity significantly increases, and suitable substitute antibiotics are as animal feed additive.
(2) the Chinese herbal feed additive raw material sources of the alternative antibiotic of the present invention are wide, method process is simple, suitable work
Industry metaplasia is produced, and this Chinese herbal feed additive residual rate is low, toxicity is low, is not detrimental to health.
(3) Chinese herbal feed additive of the alternative antibiotic of the present invention is pure natural raw material, without any chemical classes
Medicine, preparation method is simple, reaches nuisanceless requirement using this Chinese herbal feed additive poultry meat mass-energy, people have been effectively ensured
Healthy, can promote the use of.
Specific embodiment
With reference to specific embodiment, the specific embodiment of the present invention is described in detail, it is to be understood that the present invention
Protection domain do not limited by specific embodiment.
Embodiment 1：
A kind of Chinese herbal feed additive of alternative antibiotic, by being made up of following components by weight：GL-B 2
Part, 3 parts of common yam rhizome powder, 1 part of quassia, 2 parts of leatherleaf mahonia, 1 part of semen armeniacae amarae, 3 parts of corydlis bungeana, 2 parts of ching-chieh, 2 parts of rabdosia lophanthide, centella
1 part, 2 parts of the capsule of weeping forsythia, 2 parts of Radix Isatidis, 2 parts of cherokee rose root, 2 parts of reinforced nutritious powder and carrier 30 as one kind part.
The preparation method of described GL-B is：Glossy ganoderma be dry, pulverize 60 mesh sieves, obtain glossy ganoderma powder；Using water extraction
Solvent extraction water extraction, reduced pressure concentration, obtain lucidum concentrating liquid；It is subsequently adding 95% ethanol of 6 times of volumes, soak at 23 DEG C
20h, soaks and carries out filtration treatment after terminating, filter residue and drying obtains pretreated glossy ganoderma powder；Pretreated glossy ganoderma powder is pressed
Solid-liquid ratio 1：5 addition distilled water, using ultrasonic extraction 30 minutes, ultrasonic power was 140W, 65 DEG C of ultrasonic temperature, ultrasonic terminate after
Filtered, taken filtrate；Filtrate is carried out centrifugal treating, centrifuge RPMs 4600r/min, centrifugation time 5min, takes supernatant to enter
Row freeze-drying, pulverized 60 mesh sieves, obtained final product GL-B；
The preparation method of described common yam rhizome powder is：By the Huaihe River mountain removal of impurities peeling of fresh collection, dry, pulverize at 60 DEG C
50 mesh sieves, obtain Huaihe River mountain meal；By Huaihe River mountain meal and complex enzyme in mass ratio 50:3 mixings, then press solid-liquid ratio 1:5 addition distilled water,
At 55 DEG C, temperature boils 60-90min, and temperature is directly dried process after boiling end, pulverized 80 mesh sieves, and obtained final product common yam rhizome powder；Described
Complex enzyme is by amylase, 1,4 beta-glucanase, zytase, cellulase in mass ratio 4：2：1：1 composition.
The preparation method of described quassia is：Quassia be dry, pulverize 80 mesh sieves；The preparation method of described leatherleaf mahonia
For：Leatherleaf mahonia be dry, pulverize 80 mesh sieves；Described amygdalate preparation method is：Semen armeniacae amarae be dry, pulverize 80
Mesh sieve；The preparation method of described corydlis bungeana is：Corydlis bungeana be dry, pulverize 80 mesh sieves；The system of described ching-chieh
Preparation Method is：Ching-chieh be dry, pulverize 80 mesh sieves；The preparation method of described rabdosia lophanthide is：Rabdosia lophanthide is dried, powder
Broken mistake 80 mesh sieve；The preparation method of described centella is：Centella be dry, pulverize 80 mesh sieves；The described capsule of weeping forsythia
Preparation method be：The capsule of weeping forsythia be dry, pulverize 80 mesh sieves；The preparation method of described Radix Isatidis is：Radix Isatidis is dried,
Pulverized 80 mesh sieves；The preparation method of described cherokee rose root is：Cherokee rose root be dry, pulverize 80 mesh sieves.
Described reinforced nutritious powder is by wheat germ powder, beer yeast powder and protein powder in mass ratio 3:4:1 composition.
Described carrier is dehulled soybean meal powder and high lactose whey powder, and dehulled soybean meal powder and high lactose whey powder are in mass ratio
6：2,60 mesh sieves pulverized in advance by dehulled soybean meal powder and high lactose whey powder.
The invention provides the preparation method of described Chinese herbal feed additive, comprise the steps：
Will be yellow to GL-B, common yam rhizome powder, quassia, leatherleaf mahonia, semen armeniacae amarae, corydlis bungeana, ching-chieh, small stream according to raw material composition
Grass, centella, the capsule of weeping forsythia, Radix Isatidis, cherokee rose root, reinforced nutritious powder and carrier mix, and obtain final product the Chinese medicine of alternative antibiotic
Feed addictive.
Addition in animal basal diet for the Chinese herbal feed additive product of the present invention is 1000 g ton.
Embodiment 2：
A kind of Chinese herbal feed additive of alternative antibiotic, by being made up of following components by weight：GL-B 4
Part, 8 parts of common yam rhizome powder, 4 parts of quassia, 5 parts of leatherleaf mahonia, 3 parts of semen armeniacae amarae, 4 parts of corydlis bungeana, 5 parts of ching-chieh, 3 parts of rabdosia lophanthide, centella
2 parts, 5 parts of the capsule of weeping forsythia, 4 parts of Radix Isatidis, 3 parts of cherokee rose root, 5 parts of reinforced nutritious powder and 50 parts of carrier.
The preparation method of described GL-B is：Glossy ganoderma be dry, pulverize 60 mesh sieves, obtain glossy ganoderma powder；Using water extraction
Solvent extraction water extraction, reduced pressure concentration, obtain lucidum concentrating liquid；It is subsequently adding 95% ethanol of 6 times of volumes, soak at 28 DEG C
20h, soaks and carries out filtration treatment after terminating, filter residue and drying obtains pretreated glossy ganoderma powder；Pretreated glossy ganoderma powder is pressed
Solid-liquid ratio 1：8 addition distilled water, using ultrasonic extraction 40 minutes, ultrasonic power was 190W, 75 DEG C of ultrasonic temperature, ultrasonic terminate after
Filtered, taken filtrate；Filtrate is carried out centrifugal treating, centrifuge RPMs 4600r/min, centrifugation time 5min, takes supernatant to enter
Row freeze-drying, pulverized 60 mesh sieves, obtained final product GL-B；
The preparation method of described common yam rhizome powder is：By the Huaihe River mountain removal of impurities peeling of fresh collection, dry, pulverize at 75 DEG C
50 mesh sieves, obtain Huaihe River mountain meal；By Huaihe River mountain meal and complex enzyme in mass ratio 50:3 mixings, then press solid-liquid ratio 1:5 addition distilled water,
At 70 DEG C, temperature boils 90min, and temperature is directly dried process after boiling end, pulverized 80 mesh sieves, and obtained final product common yam rhizome powder；Described compound
Enzyme is by amylase, 1,4 beta-glucanase, zytase, cellulase in mass ratio 4：2：1：1 composition.
The preparation method of described quassia is：Quassia be dry, pulverize 80 mesh sieves；The preparation method of described leatherleaf mahonia
For：Leatherleaf mahonia be dry, pulverize 80 mesh sieves；Described amygdalate preparation method is：Semen armeniacae amarae be dry, pulverize 80
Mesh sieve；The preparation method of described corydlis bungeana is：Corydlis bungeana be dry, pulverize 80 mesh sieves；The system of described ching-chieh
Preparation Method is：Ching-chieh be dry, pulverize 80 mesh sieves；The preparation method of described rabdosia lophanthide is：Rabdosia lophanthide is dried, powder
Broken mistake 80 mesh sieve；The preparation method of described centella is：Centella be dry, pulverize 80 mesh sieves；The described capsule of weeping forsythia
Preparation method be：The capsule of weeping forsythia be dry, pulverize 80 mesh sieves；The preparation method of described Radix Isatidis is：Radix Isatidis is dried,
Pulverized 80 mesh sieves；The preparation method of described cherokee rose root is：Cherokee rose root be dry, pulverize 80 mesh sieves.
Described reinforced nutritious powder is by wheat germ powder, beer yeast powder and protein powder in mass ratio 5:5:3 compositions.
Described carrier is dehulled soybean meal powder and high lactose whey powder, and dehulled soybean meal powder and high lactose whey powder are in mass ratio
6：2,60 mesh sieves pulverized in advance by dehulled soybean meal powder and high lactose whey powder.
The invention provides the preparation method of described Chinese herbal feed additive, comprise the steps：
Will be yellow to GL-B, common yam rhizome powder, quassia, leatherleaf mahonia, semen armeniacae amarae, corydlis bungeana, ching-chieh, small stream according to raw material composition
Grass, centella, the capsule of weeping forsythia, Radix Isatidis, cherokee rose root, reinforced nutritious powder and carrier mix, and obtain final product the Chinese medicine of alternative antibiotic
Feed addictive.
Addition in animal basal diet for the Chinese herbal feed additive product of the present invention is 1300 g ton.
Embodiment 3：
A kind of Chinese herbal feed additive of alternative antibiotic, by being made up of following components by weight：GL-B 3
Part, 5 parts of common yam rhizome powder, 2 parts of quassia, 4 parts of leatherleaf mahonia, 2 parts of semen armeniacae amarae, 3 parts of corydlis bungeana, 3 parts of ching-chieh, 2 parts of rabdosia lophanthide, centella
1 part, 3 parts of the capsule of weeping forsythia, 3 parts of Radix Isatidis, 3 parts of cherokee rose root, 4 parts of reinforced nutritious powder and 40 parts of carrier.
The preparation method of described GL-B is：Glossy ganoderma be dry, pulverize 60 mesh sieves, obtain glossy ganoderma powder；Using water extraction
Solvent extraction water extraction, reduced pressure concentration, obtain lucidum concentrating liquid；It is subsequently adding 95% ethanol of 6 times of volumes, soak at 25 DEG C
20h, soaks and carries out filtration treatment after terminating, filter residue and drying obtains pretreated glossy ganoderma powder；Pretreated glossy ganoderma powder is pressed
Solid-liquid ratio 1：6 addition distilled water, using ultrasonic extraction 35 minutes, ultrasonic power was 160W, 70 DEG C of ultrasonic temperature, ultrasonic terminate after
Filtered, taken filtrate；Filtrate is carried out centrifugal treating, centrifuge RPMs 4600r/min, centrifugation time 5min, takes supernatant to enter
Row freeze-drying, pulverized 60 mesh sieves, obtained final product GL-B；
The preparation method of described common yam rhizome powder is：By the Huaihe River mountain removal of impurities peeling of fresh collection, dry, pulverize at 70 DEG C
50 mesh sieves, obtain Huaihe River mountain meal；By Huaihe River mountain meal and complex enzyme in mass ratio 50:3 mixings, then press solid-liquid ratio 1:5 addition distilled water,
At 60 DEG C, temperature boils 70min, and temperature is directly dried process after boiling end, pulverized 80 mesh sieves, and obtained final product common yam rhizome powder；Described compound
Enzyme is by amylase, 1,4 beta-glucanase, zytase, cellulase in mass ratio 4：2：1：1 composition.
The preparation method of described quassia is：Quassia be dry, pulverize 80 mesh sieves；The preparation method of described leatherleaf mahonia
For：Leatherleaf mahonia be dry, pulverize 80 mesh sieves；Described amygdalate preparation method is：Semen armeniacae amarae be dry, pulverize 80
Mesh sieve；The preparation method of described corydlis bungeana is：Corydlis bungeana be dry, pulverize 80 mesh sieves；The system of described ching-chieh
Preparation Method is：Ching-chieh be dry, pulverize 80 mesh sieves；The preparation method of described rabdosia lophanthide is：Rabdosia lophanthide is dried, powder
Broken mistake 80 mesh sieve；The preparation method of described centella is：Centella be dry, pulverize 80 mesh sieves；The described capsule of weeping forsythia
Preparation method be：The capsule of weeping forsythia be dry, pulverize 80 mesh sieves；The preparation method of described Radix Isatidis is：Radix Isatidis is dried,
Pulverized 80 mesh sieves；The preparation method of described cherokee rose root is：Cherokee rose root be dry, pulverize 80 mesh sieves.
Described reinforced nutritious powder is by wheat germ powder, beer yeast powder and protein powder in mass ratio 4:4.5:2 compositions.
Described carrier is dehulled soybean meal powder and high lactose whey powder, and dehulled soybean meal powder and high lactose whey powder are in mass ratio
6：2,60 mesh sieves pulverized in advance by dehulled soybean meal powder and high lactose whey powder.
The invention provides the preparation method of described Chinese herbal feed additive, comprise the steps：
Will be yellow to GL-B, common yam rhizome powder, quassia, leatherleaf mahonia, semen armeniacae amarae, corydlis bungeana, ching-chieh, small stream according to raw material composition
Grass, centella, the capsule of weeping forsythia, Radix Isatidis, cherokee rose root, reinforced nutritious powder and carrier mix, and obtain final product the Chinese medicine of alternative antibiotic
Feed addictive.
Addition in animal basal diet for the Chinese herbal feed additive product of the present invention is 1800 g ton.
Embodiment 4：The Chinese herbal feed additive of the alternative antibiotic of the present invention controls curative effect to chicken infection salmonella
Really
Method：Choose 1 age in days Yellow Chicken 500 from Nanning City chicken farm, be randomly divided into 5 groups, every group 100.It is divided into
Control group, the Chinese herbal feed additive 1-3 group of alternative antibiotic of embodiment 1-3 preparation, antibiotic group.With chicken source Salmonella
Bacterium C79-1 infect 1 time (feeding 0.1mL, about 108Viable bacteria), feed product of the present invention after 5h, the alternative antibiotic of each embodiment
Chinese herbal feed additive addition in feed presses explanation in above-described embodiment 1-3；Antibiotic is apramycin sulfate, addition
It is by 1800 g ton feedings in basal diet.Continuous nursing 30 days.Statistics chicken death number, after death takes to not dead Ji Chu
Go out spleen and thymus gland, calculate index and spleen index and thymus index.
The test result to salmonella infection chicken for the Chinese herbal feed additive of the alternative antibiotic of table 1 present invention
As shown in table 1, knowable to table 1 analysis, the Chinese herbal feed additive pair of the alternative antibiotic of embodiment 1-3 preparation
Caused by salmonella, chicken infection all has good control action, no dead generation, and its Thymus and spleen index has relatively compareed significantly
Improve.Illustrate that the Chinese herbal feed additive of the alternative antibiotic of the present invention has the therapeutic effect of antibiotic and improves chicken immune
The effect of power.
Embodiment 5：The Chinese herbal feed additive of the alternative antibiotic of the present invention controls curative effect to pig ehec infection
Really
Method：Choose Luchuan pig 500 in 10-20 age in days from Nanning City pig farm, be randomly divided into 5 groups, every group 100
Head.It is grouped into control group, the Chinese herbal feed additive of the alternative antibiotic of embodiment 1-3 preparation tests 1-3 group, hydrochloric acid gold is mould
Plain antibiotic group.Use Escherichia coli O301Infection (feeding 5mL/ days, about 109Viable bacteria) 5 days, the alternative antibiotic of each test group
Chinese herbal feed additive addition in feed presses explanation in above-described embodiment 1-3；Antibiotic is aureomycin hydrochloride, in feed
Addition is by 1800 g ton being fed with material.Continuous use 3 days.Observe pig situation：Symptom disappears, diet and mental status are extensive
Multiple is normally to cure；Diarrhoea status mitigation, appetite switch to well effective；Diarrhoea status do not mitigate or increase, appetite does not switch to well no
Effect.
The therapeutic effect to coli-infection pig for the Chinese herbal feed additive of the alternative antibiotic of table 2 present invention
As shown in table 2, the Chinese herbal feed additive of the alternative antibiotic of embodiment 1-3 preparation is to pig caused by Escherichia coli
Infection all has good control action, and obvious effective rate is 96-100%, and cure rate is 58-86%.Illustrate of the present invention alternative
The Chinese herbal feed additive of antibiotic has the substitution effect of antibiotic to pig ehec infection.
The description of the aforementioned specific illustrative embodiment to the present invention illustrate that and illustration purpose.These descriptions
It is not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to above-mentioned teaching, can much be changed
And change.The purpose of selecting and describing the exemplary embodiment is that explaining that the certain principles of the present invention and its reality should
With so that those skilled in the art be capable of and utilize the present invention various different exemplary and
Various different selections and change.The scope of the present invention is intended to be limited by claims and its equivalents.
Claims (7)
1. a kind of Chinese herbal feed additive of alternative antibiotic is it is characterised in that by being made up of following components by weight：Spirit
Sesame polysaccharide 2-4 part, common yam rhizome powder 3-8 part, quassia 1-4 part, leatherleaf mahonia 2-5 part, semen armeniacae amarae 1-3 part, corydlis bungeana 3-4 part, ching-chieh
2-5 part, rabdosia lophanthide 2-3 part, centella 1-2 part, capsule of weeping forsythia 2-5 part, Radix Isatidis 2-4 part, cherokee rose root 2-3 part, reinforced nutritious powder 2-5
Part and -50 parts of carrier 30 as one kind.
2. the Chinese herbal feed additive of alternative antibiotic according to claim 1 is it is characterised in that described glossy ganoderma is many
Sugar preparation method be：Glossy ganoderma be dry, pulverize 60 mesh sieves, obtain glossy ganoderma powder；Using water extraction solvent extraction water extraction, reduce pressure dense
Contracting, obtains lucidum concentrating liquid；It is subsequently adding 95% ethanol of 6 times of volumes, at 23-28 DEG C, soaks 20h, soak and carried out after terminating
Filter is processed, and filter residue and drying obtains pretreated glossy ganoderma powder；Pretreated glossy ganoderma powder is pressed solid-liquid ratio 1：5-8 adds distillation
Water, using ultrasonic extraction 30-40 minute, ultrasonic power is 140-190W, 65-75 DEG C of ultrasonic temperature, carries out after ultrasonic end
Filter, takes filtrate；Filtrate is carried out centrifugal treating, centrifuge RPMs 4600r/min, centrifugation time 5min, takes supernatant to be freezed
Dry, pulverize 60 mesh sieves, obtain final product GL-B.
3. the Chinese herbal feed additive of alternative antibiotic according to claim 1 is it is characterised in that described common yam rhizome powder
Preparation method be：By the Huaihe River mountain removal of impurities peeling of fresh collection, dry, pulverize 50 mesh sieves at 60-75 DEG C, obtained Huai Shan thick
Powder；By Huaihe River mountain meal and complex enzyme in mass ratio 50:3 mixings, then press solid-liquid ratio 1:5 addition distilled water, at 55-70 DEG C, temperature is boiled
60-90min, temperature is directly dried process after boiling end, pulverized 80 mesh sieves, and obtained final product common yam rhizome powder.
4. alternative antibiotic according to claim 3 Chinese herbal feed additive it is characterised in that described complex enzyme by
Amylase, 1,4 beta-glucanase, zytase, cellulase in mass ratio 4：2：1：1 composition.
5. the Chinese herbal feed additive of alternative antibiotic according to claim 1 is it is characterised in that the system of described quassia
Preparation Method is：Quassia be dry, pulverize 80 mesh sieves；The preparation method of described leatherleaf mahonia is：Leatherleaf mahonia be dry, pulverize
Cross 80 mesh sieves；Described amygdalate preparation method is：Semen armeniacae amarae be dry, pulverize 80 mesh sieves；Described corydlis bungeana
Preparation method be：Corydlis bungeana be dry, pulverize 80 mesh sieves；The preparation method of described ching-chieh is：Ching-chieh is done
Dry, pulverized 80 mesh sieves；The preparation method of described rabdosia lophanthide is：Rabdosia lophanthide be dry, pulverize 80 mesh sieves；Described
The preparation method of centella is：Centella be dry, pulverize 80 mesh sieves；The preparation method of the described capsule of weeping forsythia is：By the capsule of weeping forsythia
Dry, pulverize 80 mesh sieves；The preparation method of described Radix Isatidis is：Radix Isatidis be dry, pulverize 80 mesh sieves；Institute
The preparation method stating cherokee rose root is：Cherokee rose root be dry, pulverize 80 mesh sieves.
6. the Chinese herbal feed additive of alternative antibiotic according to claim 1 is it is characterised in that described enriched nutritive
Powder is by wheat germ powder, beer yeast powder and protein powder 3-5 in mass ratio:4-5:1-3 forms.
7. the Chinese herbal feed additive of alternative antibiotic according to claim 1 is it is characterised in that described carrier is
Dehulled soybean meal powder and high lactose whey powder, dehulled soybean meal powder and high lactose whey powder in mass ratio 6：2, dehulled soybean meal powder and height breast
60 mesh sieves pulverized in advance by sugared whey powder.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610841979.4A CN106417920A (en) | 2016-09-22 | 2016-09-22 | Traditional Chinese medicine feed additive capable of replacing antibiotics and preparation method thereof |
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| CN201610841979.4A CN106417920A (en) | 2016-09-22 | 2016-09-22 | Traditional Chinese medicine feed additive capable of replacing antibiotics and preparation method thereof |
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| CN106417920A true CN106417920A (en) | 2017-02-22 |
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| CN201610841979.4A Pending CN106417920A (en) | 2016-09-22 | 2016-09-22 | Traditional Chinese medicine feed additive capable of replacing antibiotics and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114258989A (en) * | 2021-12-28 | 2022-04-01 | 湖南诺泽生物科技有限公司 | Feed additive and preparation method and application thereof |
| CN115553381A (en) * | 2022-08-22 | 2023-01-03 | 玉林师范学院 | Quassia extract, preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103947907A (en) * | 2014-05-21 | 2014-07-30 | 双胞胎（集团）股份有限公司 | Pig immune-enhanced feed additive capable of replacing antibiotic |
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2016
- 2016-09-22 CN CN201610841979.4A patent/CN106417920A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103947907A (en) * | 2014-05-21 | 2014-07-30 | 双胞胎（集团）股份有限公司 | Pig immune-enhanced feed additive capable of replacing antibiotic |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114258989A (en) * | 2021-12-28 | 2022-04-01 | 湖南诺泽生物科技有限公司 | Feed additive and preparation method and application thereof |
| CN115553381A (en) * | 2022-08-22 | 2023-01-03 | 玉林师范学院 | Quassia extract, preparation method and application thereof |
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Application publication date: 20170222 |