CN105960461B - 有效的非减数分裂等位基因渐渗 - Google Patents
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- CN105960461B CN105960461B CN201480057624.5A CN201480057624A CN105960461B CN 105960461 B CN105960461 B CN 105960461B CN 201480057624 A CN201480057624 A CN 201480057624A CN 105960461 B CN105960461 B CN 105960461B
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- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
- C12N15/8778—Swine embryos
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2800/00—Nucleic acids vectors
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- C12N2800/00—Nucleic acids vectors
- C12N2800/90—Vectors containing a transposable element
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010106589.9A CN111471719B (zh) | 2013-08-27 | 2014-04-29 | 有效的非减数分裂等位基因渐渗 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361870401P | 2013-08-27 | 2013-08-27 | |
| US61/870,401 | 2013-08-27 | ||
| PCT/US2014/035854 WO2015030881A1 (en) | 2013-08-27 | 2014-04-29 | Efficient non-meiotic allele introgression |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010106589.9A Division CN111471719B (zh) | 2013-08-27 | 2014-04-29 | 有效的非减数分裂等位基因渐渗 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105960461A CN105960461A (zh) | 2016-09-21 |
| CN105960461B true CN105960461B (zh) | 2020-03-17 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480057624.5A Active CN105960461B (zh) | 2013-08-27 | 2014-04-29 | 有效的非减数分裂等位基因渐渗 |
| CN202010106589.9A Active CN111471719B (zh) | 2013-08-27 | 2014-04-29 | 有效的非减数分裂等位基因渐渗 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN202010106589.9A Active CN111471719B (zh) | 2013-08-27 | 2014-04-29 | 有效的非减数分裂等位基因渐渗 |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US9528124B2 (enExample) |
| EP (1) | EP3039145B1 (enExample) |
| JP (2) | JP2016529904A (enExample) |
| KR (1) | KR20160048179A (enExample) |
| CN (2) | CN105960461B (enExample) |
| AP (1) | AP2016009113A0 (enExample) |
| AR (1) | AR096143A1 (enExample) |
| AU (2) | AU2014311855A1 (enExample) |
| BR (1) | BR112016004020B1 (enExample) |
| CA (1) | CA2922084C (enExample) |
| MX (1) | MX2016002564A (enExample) |
| PH (1) | PH12016500378A1 (enExample) |
| RU (1) | RU2016110827A (enExample) |
| WO (1) | WO2015030881A1 (enExample) |
Families Citing this family (69)
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| US9528124B2 (en) * | 2013-08-27 | 2016-12-27 | Recombinetics, Inc. | Efficient non-meiotic allele introgression |
| US10920242B2 (en) | 2011-02-25 | 2021-02-16 | Recombinetics, Inc. | Non-meiotic allele introgression |
| US10323236B2 (en) | 2011-07-22 | 2019-06-18 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| MX388563B (es) | 2013-10-25 | 2025-03-20 | Livestock Improvement Corporation Ltd | Marcadores geneticos y usos de los mismos. |
| EP4372090A3 (en) | 2013-11-07 | 2024-08-07 | Editas Medicine, Inc. | Crispr-related methods and compositions with governing grnas |
| CN110951779B (zh) | 2013-12-11 | 2024-04-16 | 瑞泽恩制药公司 | 用于靶向修饰基因组的方法和组合物 |
| US11053481B2 (en) | 2013-12-12 | 2021-07-06 | President And Fellows Of Harvard College | Fusions of Cas9 domains and nucleic acid-editing domains |
| US10349639B2 (en) | 2014-03-26 | 2019-07-16 | University Of Maryland, College Park | Targeted genome editing in zygotes of domestic large animals |
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| CN114262708B (zh) * | 2021-12-21 | 2024-07-02 | 西北农林科技大学 | 一种生产FecB基因g.A746G定点突变绵羊的试剂盒及其方法 |
| CN114752686B (zh) * | 2022-04-25 | 2023-05-16 | 四川省畜牧科学研究院 | 一种与兔肌肉品质性状相关的snp分子标记及其应用 |
| KR102697859B1 (ko) | 2023-09-14 | 2024-08-23 | (주)오토노머스에이투지 | 카메라에 오염이 발생했는지 여부를 실시간으로 판단하는 방법 및 이를 이용한 컴퓨팅 장치 |
Citations (1)
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| CN103025344A (zh) * | 2010-05-17 | 2013-04-03 | 桑格摩生物科学股份有限公司 | 新型dna-结合蛋白及其用途 |
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