CN105814195A - 层粘连蛋白应用于角膜内皮细胞培养 - Google Patents

层粘连蛋白应用于角膜内皮细胞培养 Download PDF

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Publication number
CN105814195A
CN105814195A CN201480065134.XA CN201480065134A CN105814195A CN 105814195 A CN105814195 A CN 105814195A CN 201480065134 A CN201480065134 A CN 201480065134A CN 105814195 A CN105814195 A CN 105814195A
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China
Prior art keywords
laminin
chain
corneal endothelial
endothelial cells
cells
Prior art date
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Pending
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CN201480065134.XA
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English (en)
Chinese (zh)
Inventor
小泉范子
奥村直毅
木下茂
F·E·克鲁斯
U·施罗泽尔-施瑞哈特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Doshisha Co Ltd
Kyoto Prefectural PUC
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Senju Pharmaceutical Co Ltd
Doshisha Co Ltd
Kyoto Prefectural PUC
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Application filed by Senju Pharmaceutical Co Ltd, Doshisha Co Ltd, Kyoto Prefectural PUC filed Critical Senju Pharmaceutical Co Ltd
Publication of CN105814195A publication Critical patent/CN105814195A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201480065134.XA 2013-11-27 2014-11-26 层粘连蛋白应用于角膜内皮细胞培养 Pending CN105814195A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013244972 2013-11-27
JP2013-244972 2013-11-27
PCT/JP2014/081917 WO2015080297A1 (en) 2013-11-27 2014-11-26 Application of laminin to corneal endothelial cell culture

Publications (1)

Publication Number Publication Date
CN105814195A true CN105814195A (zh) 2016-07-27

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CN201480065134.XA Pending CN105814195A (zh) 2013-11-27 2014-11-26 层粘连蛋白应用于角膜内皮细胞培养

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Country Link
US (1) US11624053B2 (https=)
EP (1) EP3074508B1 (https=)
JP (3) JP6470286B2 (https=)
CN (1) CN105814195A (https=)
BR (1) BR112016011096A2 (https=)
CA (1) CA2931280A1 (https=)
ES (1) ES2763433T3 (https=)
MX (1) MX2016006915A (https=)
RU (1) RU2704984C1 (https=)
WO (1) WO2015080297A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112522179A (zh) * 2020-12-23 2021-03-19 江苏艾尔康生物医药科技有限公司 一种角膜内皮细胞的分离培养方法
CN113015429A (zh) * 2018-10-02 2021-06-22 学校法人同志社 用于保存角膜内皮细胞的方法和容器

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2858173C (en) 2011-12-06 2023-09-26 Advanced Cell Technology, Inc. Method of directed differentiation producing corneal endothelial cells, compositions thereof, and uses thereof
JP6770435B2 (ja) 2014-10-31 2020-10-14 京都府公立大学法人 ラミニンによる網膜および神経の新規治療
RU2718062C2 (ru) 2014-10-31 2020-03-30 Сэндзю Фармасьютикал Ко., Лтд. Новое лечение роговицы с применением ламинина
JP6849957B2 (ja) * 2015-11-10 2021-03-31 国立大学法人京都大学 ラミニンフラグメント含有培地を用いる細胞培養方法
JP6605618B2 (ja) * 2015-11-10 2019-11-20 日機装株式会社 細胞支持複合体および細胞支持複合体の製造方法
EP4733316A3 (en) * 2017-01-31 2026-05-06 Osaka University Differentiation control method for pluripotent stem cells
WO2019079809A1 (en) * 2017-10-22 2019-04-25 The Johns Hopkins University BIOMIMETIC PLATFORMS FOR MODELING VASCULAR PHYSIOPATHOLOGY, DIAGNOSIS AND THERAPY
WO2019102593A1 (ja) * 2017-11-24 2019-05-31 株式会社Ihi 細胞培養装置
JP6664755B1 (ja) * 2018-10-02 2020-03-13 学校法人同志社 角膜内皮細胞を保存するための方法および容器
CN113557059A (zh) * 2019-03-12 2021-10-26 日产化学株式会社 角膜疾病治疗剂
JP2023025311A (ja) * 2020-02-05 2023-02-22 味の素株式会社 タンパク質の製造方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1893988A (zh) * 2003-10-10 2007-01-10 细胞生物工程公司 用于在生物聚合物上培养角膜内皮细胞和相关细胞以及产生人工角膜移植物的方法和组合物
CN102597217A (zh) * 2009-10-08 2012-07-18 国立大学法人大阪大学 人多能干细胞用培养基质及其用途
WO2013012087A1 (ja) * 2011-07-15 2013-01-24 国立大学法人大阪大学 角膜内皮細胞の調製方法

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4678783B1 (en) 1983-11-04 1995-04-04 Asahi Chemical Ind Substituted isoquinolinesulfonyl compounds
EP1195372A1 (en) 1994-04-18 2002-04-10 Mitsubishi Pharma Corporation N-heterocyclic substituted benzamide derivatives with antihypertensive activity
JP3421217B2 (ja) 1995-11-20 2003-06-30 麒麟麦酒株式会社 Ｒｈｏ標的タンパク質Ｒｈｏキナーゼ
EP0954328A4 (en) 1996-06-05 2002-07-17 Gen Hospital Corp Laminin-5 and the production of a basement membrane structure
FR2765781B1 (fr) 1997-07-08 1999-09-24 Gioia Bruno Di Procede de fabrication d'un accessoire de mode, dispositif pour la mise en oeuvre du procede et accessoire de mode ainsi realise
US6042262A (en) 1997-07-29 2000-03-28 Stryker Technologies Corportion Apparatus for storing, mixing, and dispensing two-component bone cement
US6693169B1 (en) 1998-10-13 2004-02-17 The General Hospital Corporation Laminin 5, 13 and 14 and uses thereof
EP1177290A2 (en) 1999-04-30 2002-02-06 Biostratum, Inc. Recombinant laminin 5
US6635616B2 (en) 2000-05-01 2003-10-21 The General Hospital Corporation Laminin 15
US6933273B2 (en) 2000-12-21 2005-08-23 Karl Tryggvason Isolated laminin 10
PE20020958A1 (es) 2001-03-23 2002-11-14 Bayer Corp Inhibidores de la rho-quinasa
UY27224A1 (es) 2001-03-23 2002-10-31 Bayer Corp Inhibidores de la rho-quinasa
US7109208B2 (en) 2001-04-11 2006-09-19 Senju Pharmaceutical Co., Ltd. Visual function disorder improving agents
WO2002100833A1 (en) 2001-06-12 2002-12-19 Sumitomo Pharmaceuticals Company, Limited Rho KINASE INHIBITORS
JP4505228B2 (ja) 2002-01-10 2010-07-21 バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト Ｒｈｏ−キナーゼ阻害剤
MXPA04007196A (es) 2002-01-23 2005-06-08 Bayer Pharmaceuticals Corp Inhibidores de rho-quinasa.
JP2004024852A (ja) 2002-04-30 2004-01-29 Amniotec:Kk 角膜内皮様シート、及びその作製方法
WO2003092762A1 (en) * 2002-04-30 2003-11-13 Amniotec Inc. Corneal endothelium-like sheet and method of constructing the same
EP1541559A4 (en) 2002-07-22 2007-08-22 Asahi Kasei Pharma Corp 5-SUBSTITUTED ISOQUINOLINE DERIVATIVE
CA2400996A1 (en) 2002-09-03 2004-03-03 Lisa Mckerracher 1,4-substituted cyclohexane derivatives
US7160894B2 (en) 2003-06-06 2007-01-09 Asahi Kasei Pharma Corporation Tricyclic compound
WO2005003101A2 (en) 2003-07-02 2005-01-13 Biofocus Discovery Limited Pyrazine and pyridine derivatives as rho kinase inhibitors
WO2005039564A1 (en) 2003-10-02 2005-05-06 Vertex Pharmaceuticals Incorporated Phthalimide compounds useful as protein kinase inhibitors
WO2005034866A2 (en) 2003-10-06 2005-04-21 Glaxo Group Limited Preparation of 1, 6, 7- trisubstituted azabenzimidazoles as kinase inhibitors
JP2007507547A (ja) 2003-10-06 2007-03-29 グラクソ　グループ　リミテッド キナーゼ阻害剤としての１，７−二置換アザベンゾイミダゾールの調製
ES2387780T3 (es) 2003-10-06 2012-10-01 Glaxosmithkline Llc Preparación de azabencimidazoles 1,6-disustituidos como inhibidores de quinasas
US20070092550A1 (en) 2003-10-10 2007-04-26 Cellular Bioengineering, Inc. Methods and compositions for growing corneal endothelial and related cells on biopolymers and creation of artifical corneal transplants
CN1898377A (zh) 2003-10-10 2007-01-17 细胞生物工程公司 人角膜内皮细胞以及获得和培养用于角膜细胞移植的细胞的方法
JP2007015928A (ja) 2003-10-15 2007-01-25 Ube Ind Ltd 新規オレフィン誘導体
EP1679308B1 (en) 2003-10-15 2013-07-24 Ube Industries, Ltd. Novel indazole derivative
JP2007008816A (ja) 2003-10-15 2007-01-18 Ube Ind Ltd 新規イソキノリン誘導体
EP2929782A1 (en) 2004-01-23 2015-10-14 Ocata Therapeutics, Inc. Improved modalities for the treatment of degenerative diseases of the retina
US8039585B2 (en) 2004-02-12 2011-10-18 The United States Of America As Represented By The Department Of Health And Human Services Therapeutic administration of the scrambled anti-angiogenic peptide C16Y
CA2556589A1 (en) 2004-02-24 2005-09-01 Bioaxone Therapeutique Inc. 4-substituted piperidine derivatives
AR049333A1 (es) 2004-04-02 2006-07-19 Vertex Pharma Azaindoles inhibidores de proteinquinasas rock y otras proteinas quinasas. composiciones farmaceuticas.
WO2006057270A1 (ja) 2004-11-26 2006-06-01 Asahi Kasei Pharma Corporation 含窒素３環化合物
CA2621181C (en) 2005-08-30 2011-04-19 Asahi Kasei Pharma Corporation 5-isoquinolinesulfonamide compounds
JP5255846B2 (ja) 2006-01-19 2013-08-07 千寿製薬株式会社 生体内で細胞増殖可能な角膜内皮製剤
US20090175835A1 (en) 2006-02-07 2009-07-09 Korea Institute Of Radiological & Medical Sciences Composition for treating damage of central or peripheral nerve system
US20100028407A1 (en) 2006-04-27 2010-02-04 University Of Louisville Research Foundation, Inc. Layered bio-adhesive compositions and uses thereof
US8951799B2 (en) 2007-01-04 2015-02-10 Biolamina Ab Composition and method for enabling proliferation of pluripotent stem cells
WO2009028631A1 (ja) 2007-08-29 2009-03-05 Senju Pharmaceutical Co., Ltd. 角膜内皮細胞接着促進剤
US20090306772A1 (en) 2008-04-18 2009-12-10 The Regents Of The University Of California Ocular Scaffolds and Methods for Subretinal Repair of Bruch's Membrane
US8680182B2 (en) 2009-06-04 2014-03-25 Clemson University Research Foundation Methods for promoting the revascularization and reenervation of CNS lesions
JP2011010653A (ja) 2009-06-05 2011-01-20 Kumamoto Univ 細胞の分化誘導方法
RU2418067C1 (ru) 2009-12-03 2011-05-10 Государственное образовательное учреждение высшего профессионального образования "Оренбургский государственный университет" Способ культивирования клеток
WO2011080984A1 (en) 2009-12-29 2011-07-07 Senju Pharmaceutical Co., Ltd. Therapeutic agent (y - 39983 ) for corneal endothelial dysfunction
BR112013017629A2 (pt) 2010-12-17 2017-04-18 Biolamina Ab laminina-521 recombinante
JPWO2012173207A1 (ja) 2011-06-14 2015-02-23 独立行政法人理化学研究所 網膜細胞への分化誘導方法
WO2013047763A1 (ja) 2011-09-29 2013-04-04 オリエンタル酵母工業株式会社 ラミニン５１１を含んだ系で哺乳類細胞を培養する方法
IL287381B2 (en) 2011-11-14 2024-04-01 Astellas Inst For Regenerative Medicine Pharmaceutical preparations of human rpe cells and uses thereof
EP2784152B1 (en) 2011-11-25 2019-04-10 Sumitomo Chemical Company, Limited Methods for producing retinal tissue and retina-related cell
JP5985207B2 (ja) 2011-11-25 2016-09-06 住友化学株式会社 網膜色素上皮細胞の製造方法
CA2858173C (en) * 2011-12-06 2023-09-26 Advanced Cell Technology, Inc. Method of directed differentiation producing corneal endothelial cells, compositions thereof, and uses thereof
WO2013148377A1 (en) 2012-03-25 2013-10-03 The Board Of Trustees Of The Leland Stanford Junior University Methods for modulating hair growth using truncated laminin-511
TR201807259T4 (tr) 2012-12-03 2018-06-21 Biolamina Ab Rpe hücreleri üretim yöntemleri.
JP6518878B2 (ja) 2013-10-09 2019-05-29 株式会社ヘリオス 網膜色素上皮細胞の製造方法
JP6770435B2 (ja) 2014-10-31 2020-10-14 京都府公立大学法人 ラミニンによる網膜および神経の新規治療
RU2718062C2 (ru) 2014-10-31 2020-03-30 Сэндзю Фармасьютикал Ко., Лтд. Новое лечение роговицы с применением ламинина
EP3813853A4 (en) 2018-06-29 2022-04-06 Platelet Biogenesis, Inc. DELIVERY COMPOSITIONS AND METHODS OF USE

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1893988A (zh) * 2003-10-10 2007-01-10 细胞生物工程公司 用于在生物聚合物上培养角膜内皮细胞和相关细胞以及产生人工角膜移植物的方法和组合物
CN102597217A (zh) * 2009-10-08 2012-07-18 国立大学法人大阪大学 人多能干细胞用培养基质及其用途
WO2013012087A1 (ja) * 2011-07-15 2013-01-24 国立大学法人大阪大学 角膜内皮細胞の調製方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MONIQUE AUMAILLEY 等: "A simplified laminin nomenclature", 《MATRIX BIOLOGY》 *
李姝燕: "层粘连蛋白作用下角膜内皮细胞增殖与细胞骨架的相关性", 《眼科研究》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113015429A (zh) * 2018-10-02 2021-06-22 学校法人同志社 用于保存角膜内皮细胞的方法和容器
CN112522179A (zh) * 2020-12-23 2021-03-19 江苏艾尔康生物医药科技有限公司 一种角膜内皮细胞的分离培养方法

Also Published As

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WO2015080297A1 (en) 2015-06-04
ES2763433T3 (es) 2020-05-28
MX2016006915A (es) 2017-01-23
JP2019054828A (ja) 2019-04-11
RU2704984C1 (ru) 2019-11-01
CA2931280A1 (en) 2015-06-04
US20170002318A1 (en) 2017-01-05
RU2016125225A (ru) 2018-01-09
EP3074508B1 (en) 2019-11-06
JP2016539641A (ja) 2016-12-22
EP3074508A1 (en) 2016-10-05
US11624053B2 (en) 2023-04-11
JP2020188778A (ja) 2020-11-26
BR112016011096A2 (pt) 2017-09-19
JP6470286B2 (ja) 2019-02-13

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Application publication date: 20160727