CN105491883B - 细胞稳定化 - Google Patents
细胞稳定化 Download PDFInfo
- Publication number
- CN105491883B CN105491883B CN201480044962.5A CN201480044962A CN105491883B CN 105491883 B CN105491883 B CN 105491883B CN 201480044962 A CN201480044962 A CN 201480044962A CN 105491883 B CN105491883 B CN 105491883B
- Authority
- CN
- China
- Prior art keywords
- acid
- cell
- apoptosis
- inhibitor
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- LCOIAYJMPKXARU-VAWYXSNFSA-N O=C(/C=C/c1ccccc1)NC(C(Cl)(Cl)Cl)NC(Nc1cccc2c1nccc2)=S Chemical compound O=C(/C=C/c1ccccc1)NC(C(Cl)(Cl)Cl)NC(Nc1cccc2c1nccc2)=S LCOIAYJMPKXARU-VAWYXSNFSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361834517P | 2013-06-13 | 2013-06-13 | |
| US61/834,517 | 2013-06-13 | ||
| PCT/US2014/042396 WO2015002729A2 (en) | 2013-06-13 | 2014-06-13 | Cell stabilization |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105491883A CN105491883A (zh) | 2016-04-13 |
| CN105491883B true CN105491883B (zh) | 2018-11-02 |
Family
ID=52144261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480044962.5A Expired - Fee Related CN105491883B (zh) | 2013-06-13 | 2014-06-13 | 细胞稳定化 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20160135446A1 (https=) |
| EP (2) | EP3007556B1 (https=) |
| JP (1) | JP6604942B2 (https=) |
| CN (1) | CN105491883B (https=) |
| CA (1) | CA2915250A1 (https=) |
| WO (1) | WO2015002729A2 (https=) |
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| MX2010007419A (es) | 2008-01-04 | 2010-11-12 | Intellikine Inc | Ciertas entidades quimicas, composiciones y metodos. |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| EP2598660B1 (en) | 2010-07-26 | 2017-03-15 | Biomatrica, INC. | Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures |
| WO2012018639A2 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
| ES2637113T3 (es) | 2011-01-10 | 2017-10-10 | Infinity Pharmaceuticals, Inc. | Procedimientos para preparar isoquinolinonas y formas sólidas de isoquinolinonas |
| US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| AU2013337717B2 (en) | 2012-11-01 | 2018-10-25 | Infinity Pharmaceuticals, Inc. | Treatment of cancers using PI3 kinase isoform modulators |
| US9725703B2 (en) | 2012-12-20 | 2017-08-08 | Biomatrica, Inc. | Formulations and methods for stabilizing PCR reagents |
| WO2015160975A2 (en) | 2014-04-16 | 2015-10-22 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| CN106687580A (zh) * | 2014-06-10 | 2017-05-17 | 生物马特里卡公司 | 在环境温度下稳定血液样品中的代谢活性细胞 |
| ES2786373T3 (es) | 2014-06-10 | 2020-10-09 | Biomatrica Inc | Estabilización de trombocitos a temperaturas ambiente |
| ES2818569T3 (es) | 2015-09-09 | 2021-04-13 | Drawbridge Health Inc | Métodos para la recopilación, estabilización y conservación de muestras |
| KR20250047404A (ko) | 2015-12-08 | 2025-04-03 | 바이오매트리카 인코포레이티드 | 적혈구 침강 속도의 감소 |
| WO2017130756A1 (ja) * | 2016-01-25 | 2017-08-03 | 学校法人 慶應義塾 | 小胞体ストレスを標的とする椎間板変性症に対する治療薬 |
| KR101662975B1 (ko) * | 2016-02-15 | 2016-10-06 | 서울대학교산학협력단 | 간암 치료 또는 예방용 조성물 |
| JP7019590B2 (ja) | 2016-03-31 | 2022-02-15 | バークレー ライツ,インコーポレイテッド | 核酸安定化試薬、キット、及びその使用方法 |
| SG11201811237WA (en) | 2016-06-24 | 2019-01-30 | Infinity Pharmaceuticals Inc | Combination therapies |
| EP3656382A1 (en) | 2017-01-30 | 2020-05-27 | Université de Liège | Perk and ire-1a inhibitors against neurodevelopmental disorders |
| CN106963769B (zh) * | 2017-03-03 | 2019-10-25 | 深圳大学 | 含pi3k抑制剂和perk抑制剂的药物组合物及其应用 |
| GB201804227D0 (en) * | 2018-03-16 | 2018-05-02 | Univ Warwick | Cryopreserving compositions |
| CN114615886A (zh) * | 2019-08-29 | 2022-06-10 | 得克萨斯大学体系董事会 | 细胞冷冻保存培养基 |
| CN111418579B (zh) * | 2020-04-13 | 2021-05-18 | 广东华夏健康生命科学有限公司 | 一种脂肪组织的保存方法、脂肪组织的保存液及其制备方法 |
| JP7741100B2 (ja) | 2020-05-04 | 2025-09-17 | アムジェン インコーポレイテッド | ミエロイド細胞に発現するトリガー受容体2アゴニストとしての複素環化合物及び使用方法 |
| CN112210594B (zh) * | 2020-11-12 | 2023-09-19 | 苏州创澜生物科技有限公司 | 一种逆转录试剂的冻干保护剂 |
| CN112210593B (zh) * | 2020-11-12 | 2023-09-19 | 苏州创澜生物科技有限公司 | 一种冻干保护剂、可冻干的pcr试剂及其应用 |
| CN113261557A (zh) * | 2021-05-28 | 2021-08-17 | 广东先康达生物科技有限公司 | 一种干细胞冻存液及干细胞冻存方法 |
| CN115363016B (zh) * | 2022-08-09 | 2023-07-18 | 广州明迅生物科技有限责任公司 | 细胞储存液及其应用 |
| CN115777693B (zh) * | 2023-02-03 | 2023-04-18 | 苏州依科赛生物科技股份有限公司 | 一种细胞冻存液、制备方法、应用方法及用途 |
| WO2025240630A1 (en) * | 2024-05-14 | 2025-11-20 | Abbott Laboratories | Reagent compositions for isothermal amplification of nucleic acids |
Citations (4)
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| US6872357B1 (en) * | 2000-11-22 | 2005-03-29 | Quadrant Drug Delivery Limited | Formulation of preservation mixtures containing sensitive biologicals to be stabilized for ambient temperature storage by drying |
| CN1747971A (zh) * | 2002-12-10 | 2006-03-15 | 诺瓦提斯公司 | 抗Nogo A的抗体(“11C7”)及其药物用途 |
| CN101360822A (zh) * | 2005-12-01 | 2009-02-04 | 生物马特里卡公司 | 用于生命科学的样品存储和样品管理的综合 |
| CN102947082A (zh) * | 2010-04-06 | 2013-02-27 | 金沃特公司 | 生物材料的稳定化的化学脱水 |
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-
2014
- 2014-06-13 WO PCT/US2014/042396 patent/WO2015002729A2/en not_active Ceased
- 2014-06-13 US US14/895,475 patent/US20160135446A1/en not_active Abandoned
- 2014-06-13 EP EP14819510.0A patent/EP3007556B1/en active Active
- 2014-06-13 JP JP2016519695A patent/JP6604942B2/ja not_active Expired - Fee Related
- 2014-06-13 EP EP19209890.3A patent/EP3632208A1/en not_active Withdrawn
- 2014-06-13 CA CA2915250A patent/CA2915250A1/en not_active Abandoned
- 2014-06-13 CN CN201480044962.5A patent/CN105491883B/zh not_active Expired - Fee Related
-
2017
- 2017-12-21 US US15/850,805 patent/US20180184644A1/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6872357B1 (en) * | 2000-11-22 | 2005-03-29 | Quadrant Drug Delivery Limited | Formulation of preservation mixtures containing sensitive biologicals to be stabilized for ambient temperature storage by drying |
| CN1747971A (zh) * | 2002-12-10 | 2006-03-15 | 诺瓦提斯公司 | 抗Nogo A的抗体(“11C7”)及其药物用途 |
| CN101360822A (zh) * | 2005-12-01 | 2009-02-04 | 生物马特里卡公司 | 用于生命科学的样品存储和样品管理的综合 |
| CN102947082A (zh) * | 2010-04-06 | 2013-02-27 | 金沃特公司 | 生物材料的稳定化的化学脱水 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015002729A2 (en) | 2015-01-08 |
| US20160135446A1 (en) | 2016-05-19 |
| JP6604942B2 (ja) | 2019-11-13 |
| EP3632208A1 (en) | 2020-04-08 |
| EP3007556A2 (en) | 2016-04-20 |
| WO2015002729A3 (en) | 2015-05-07 |
| EP3007556B1 (en) | 2020-05-20 |
| EP3007556A4 (en) | 2017-03-08 |
| CN105491883A (zh) | 2016-04-13 |
| US20180184644A1 (en) | 2018-07-05 |
| JP2016522221A (ja) | 2016-07-28 |
| CA2915250A1 (en) | 2015-01-08 |
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