CN105452287A - 免疫抑制性TGF-β信号转换器 - Google Patents
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- CN105452287A CN105452287A CN201480034691.5A CN201480034691A CN105452287A CN 105452287 A CN105452287 A CN 105452287A CN 201480034691 A CN201480034691 A CN 201480034691A CN 105452287 A CN105452287 A CN 105452287A
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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| EP (2) | EP2986636B1 (https=) |
| JP (1) | JP6578271B2 (https=) |
| CN (1) | CN105452287A (https=) |
| CA (1) | CA2909701C (https=) |
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| MX2014001222A (es) * | 2011-07-29 | 2014-09-15 | Univ Pennsylvania | Receptores coestimuladores de cambio. |
| US10584158B2 (en) * | 2013-04-17 | 2020-03-10 | Baylor College Of Medicine | Immunosuppressive TGF-β signal converter |
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- 2014-04-17 EP EP18198300.8A patent/EP3470423B1/en active Active
- 2014-04-17 WO PCT/US2014/034570 patent/WO2014172584A1/en not_active Ceased
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2020
- 2020-01-15 US US16/743,987 patent/US20200140520A1/en not_active Abandoned
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| CN113150167A (zh) * | 2020-01-22 | 2021-07-23 | 中国人民解放军总医院第五医学中心 | 一种能够反转pd-1免疫抑制信号的car t细胞结构em1设计 |
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| CN115698038A (zh) * | 2020-06-01 | 2023-02-03 | 上海君赛生物科技有限公司 | 信号转换受体及其用途 |
| CN114525260A (zh) * | 2022-02-24 | 2022-05-24 | 深圳市先康达生命科学有限公司 | 一种同时表达融合蛋白及嵌合抗原受体的免疫细胞及其应用 |
| CN114540311A (zh) * | 2022-02-24 | 2022-05-27 | 深圳市先康达生命科学有限公司 | 一种免疫细胞及其应用 |
| CN118109416A (zh) * | 2023-03-30 | 2024-05-31 | 广州百吉生物制药有限公司 | 功能增强型工程化免疫细胞及其制备和应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20200140520A1 (en) | 2020-05-07 |
| JP2016520302A (ja) | 2016-07-14 |
| JP6578271B2 (ja) | 2019-09-18 |
| HK1220704A1 (en) | 2017-05-12 |
| EP3470423A1 (en) | 2019-04-17 |
| CA2909701C (en) | 2022-12-06 |
| WO2014172584A1 (en) | 2014-10-23 |
| CA2909701A1 (en) | 2014-10-23 |
| EP2986636B1 (en) | 2018-11-14 |
| US20160075755A1 (en) | 2016-03-17 |
| US10584158B2 (en) | 2020-03-10 |
| EP2986636A1 (en) | 2016-02-24 |
| EP3470423B1 (en) | 2021-10-06 |
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