CN105411931A - Whitening cosmetic composition - Google Patents
Whitening cosmetic composition Download PDFInfo
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- CN105411931A CN105411931A CN201510900820.0A CN201510900820A CN105411931A CN 105411931 A CN105411931 A CN 105411931A CN 201510900820 A CN201510900820 A CN 201510900820A CN 105411931 A CN105411931 A CN 105411931A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The invention discloses a whitening cosmetic composition which comprises, by weight percentage, 0.01-5.00% of glycyrrhiza glabra extract, 0.1-10.00% of whitening compound, 0.01-10.00% of citrus peel extract and 75.00-99.85% of cosmetic auxiliary material substrate, wherein the whitening compound comprises water, butanediol, arbutin, citric acid, sodium sulphite, acetyl tyrosine, saxifraga sarmentosa extract, peony root extract, amino-propanol ascorbic acid phosphate ester, radix scutellariae root extract, glutathione and hydrolyzed mirabalan. The whitening cosmetic composition contains the glycyrrhiza glabra extract, the whitening compound and the citrus peel extract, and the composition has safe and efficient skin whitening effects.
Description
Technical field
The present invention relates to a kind of cosmetic composition, belong to daily chemical products technical field, particularly relate to a kind of containing Glycyrrhiza glabra L. extract, whitening complex and peel of Citrus reticulata Blanco extract cosmetic lightening compositions, said composition has skin whitening effects safely and effectively.
Background technology
In normal state, the color of human skin depends on melanic content and distribution, so the core content of lightening mechanism is exactly the formation of check melanin and accelerates melanic decomposition.The physiological process that melanin is formed and discharges is summarised as substantially: melanocyte produces melanin; Melanin granule is shifted to horn cell by melanocyte dendritic processes; The melanin granule of angle of shift cell plastid goes upward to horny layer with epidermis cell, and comes off along with horny layer and drain.
Currently marketed white-making ingredient, mostly based on the activity of restraint of tyrosinase, the permeability that this single inhibiting mechanism adds active matter is undesirable, make the effect of these whitening products poor, and these a large amount of whitening agents remain in the zest and anaphylaxis that skin can cause again skin, effect demand of consumer to whitening product can not be met, so existing whitening product formula needs necessity perfect further.
Summary of the invention
The object of the present invention is to provide a kind of whitening cosmetic compound, it contains Glycyrrhiza glabra L. extract, whitening complex and peel of Citrus reticulata Blanco extract, and said composition has skin whitening effects safely and effectively.
The invention provides one lightening compositions safely and effectively, by weight percentage, comprise following component:
The Glycyrrhiza glabra L. extract of 0.01-5.00%;
The whitening complex of 0.1-10.00%, wherein the composition of whitening complex is water, butanediol, arbutin, citric acid, sodium sulfite, Acetyl Tyrosine, aaron's beard extract, peony root extractive, aminopropanol ascorbic acid phosphoric acid esters, scutellariae,radix extract, glutathion, hydrolysis mirabalan;
The peel of Citrus reticulata Blanco extract of 0.01-10.00%;
The cosmetic substrate of 75.00-99.85%.
The Glycyrrhiza glabra L. extract that the present invention uses is the flavonoid compound extracted from Glycyrrhiza glabra L., wherein be mainly Polyphenols flavone--glabridin, it is a kind of excellent whitening raw material, its whitening function is important is by the suppression to tyrosinase activity, thus the generation of effective check melanin, reach whitening effect, in addition, licoflavone also has good antiinflammatory action, can suppress inflammation and the anaphylaxis of skin.
The licoflavone used in the present invention can be represented by formula below:
Wherein, R and R1 is independently H or alkyl.
Glycyrrhiza glabra L. extract used in the present invention has Japanese ball to be apt to the glabridin commodity PT-10 of (MaruzenpharmaCO., the LTD) of pharmacy; PT-20; PT-40 is containing glabridin 10%; 20%; Huang-henna the powder of 40% also can be the GD-2186 of Shanghai Ao Li company; GD-2189 is containing glabridin 90%; The powdery product of 40%, Glycyrrhiza glabra L. extract preferably accounts for 0.01 ~ 5.00% of cosmetic composition, is more preferably 0.1-2.0%.
whitening complex
The present invention use whitening complex be water, butanediol, arbutin, citric acid, sodium sulfite, Acetyl Tyrosine, aaron's beard extract, peony root extractive, aminopropanol ascorbic acid phosphoric acid esters, scutellariae,radix extract, glutathion, hydrolysis mirabalan.Wherein the ratio of each component is about: water 40-50%, butanediol 40-50%, arbutin 0.1-1%, citric acid 0.1-1%, sodium sulfite 0.1-1%, Acetyl Tyrosine 0.1-1%, aaron's beard extract 0.01-0.5%, peony root extractive 0.01-0.5%, aminopropanol ascorbic acid phosphoric acid esters 0.001-0.1%, scutellariae,radix extract 0.01-0.5%, glutathion 0.001-0.1%, hydrolysis mirabalan 0.01-0.5%
In addition, whitening complex is preferably: water 48.9930%, butanediol 48.7511%, arbutin 0.4750%, citric acid 0.4750%, sodium sulfite 0.4750%, Acetyl Tyrosine 0.1425%, aaron's beard extract 0.1188%, peony root extractive 0.0855%, aminopropanol ascorbic acid phosphoric acid esters 0.04725%, scutellariae,radix extract 0.0428%, paddy Guang are sweet 0.0048%, hydrolysis mirabalan 0.3890%.
Whitening complex of the present invention can be bought with AlwhiteComplex trade name by a Japanese ball company (ICHIMAROPHRCOS), and it is 0.1-10% that whitening complex accounts for cosmetics ratio, is preferably 0.5-5%, is more preferably 2-5%.
The effective ingredient of the extract of the peel of Citrus reticulata Blanco that the present invention uses is flavonoid, has O-polymethoxyflavone structure.In flavonoid, polymethoxyflavone class is the characteristic component of citrus, does not almost have in other veterinary antibiotics, and it is the material replacing 5 methoxyl groups on flavonoid.
This peel of Citrus reticulata Blanco extract can obtain in order to below method:
After peel of Citrus reticulata Blanco pure water, carry out drying.After being pulverized by dewatered peel of Citrus reticulata Blanco, utilize merceration extraction method at ambient temperature, propose effective ingredient through 40-48 hour.After the content extracted utilizes 250um object screen cloth once to filter, by centrifugalize, obtain supernatant.Again above-mentioned supernatant is filtered in order with 3um, 1um, 0.5um object filter paper afterwards.Add 1.3-butanediol, then obtain peel of Citrus reticulata Blanco extract with after 0.2-0.3um object filter paper filtering.
The peel of Citrus reticulata Blanco extract used in the present invention is purchased from ICHIMARUPHARCOSCO., LTD., and commodity are called ManarinClear.In the present invention, the content of preferred peel of Citrus reticulata Blanco extract is 0.1-10%, is more selected from 0.5-5%, lower than 0.1% when, substantially do not improve the effect of skin appearance, higher than 10% time, the change of product taste can be caused.
In order to improve aesthetic, give skin-nourishing, prevent quality deterioration etc., can in the scope not damaging effect of the present invention, make in cosmetic composition with the present invention, suitably can coordinate the various compositions being generally used for shape material compositions except mentioned component as required.Specifically, such as can list: water-soluble macromolecule, semi-synthetic water soluble polymer, Inorganic water-soluble macromolecule, UV absorbent, metal ion chelation agent, lower alcohol, polyhydric alcohol, monosaccharide, oligosaccharide, polysaccharide, aminoacid, organic amine, antiseptic, PH regulator, vitamins, plant extraction elite, antioxidant, antioxidation auxiliary agent, spice, water, skin moistening oils and fats etc.These compositions can be one or more combinations.
This natural water soluble polymer can be: arabic gum, Tragacanth, galactan, guar gum, locust bean gum, carrageenan, pectin, alginate jelly, starch, dextran, succinoglycan, amylopectin, collagen, gelatin etc.
This semisynthetic water soluble polymer can be: carboxymethyl starch, methylhydroxypropyl starch, methylcellulose, methylhydroxypropylcellulose, hydroxypropyl cellulose, carboxymethyl cellulose, sodium carboxymethyl cellulose, microcrystalline Cellulose, sodium alginate, alginic acid propylene glycol ester etc.
This Inorganic water-soluble macromolecule can be: bentonite, Magnesiumaluminumsilicate, LAPONITE, Strese Hofmann's hectorite. etc.
This UV absorbent can be: the benzophenone series etc. such as the cinnamic acid such as salicylic acid series, cinnamic acid monooctyl ester series, the 4-hydroxyl-3-carboxyl benzophenones such as ortho-aminobenzoic acid series, the ethylhexyl salicylate such as para-amino benzoic acid series, menthol-N-S cetyl o-aminobenzoa such as para-amino benzoic acid monoglyceride.UV absorbent can be used alone and also can be used in combination.
This metal ion chelation agent can be: EDETATE SODIUM, EDTA, hydroxyethane diphosphonic acid etc.
This Lower alcohols can be: ethanol, isopropyl alcohol, the tert-butyl alcohol etc.
This polyhydric alcohols can be: glycerol, propylene glycol, butanediol, sorbitol etc.
This monosaccharide example can be: the alduronic acid etc. such as the amino sugars such as the deoxysaccharide such as octose, L-fucose, GLUCOSAMINE, D-galacturonic acid such as the heptose such as hexose, aldopentose, octulose such as the pentose such as tetrose, D-R, D-Glucose such as the triose such as D-glyceraldehyde, D-erythrose.
This oligosaccharide can be: lactose, cottonseed sugar, planteose etc.
This polysaccharide can be: chondroitin sulfate, chitosan, galactan etc.
This aminoacid can be basic amino acid, the glutathion etc. such as the neutral amino acids such as threonine, sulfydryl lysine amino acid derivativges etc.
This organic amine can be: monoethanolamine, triethanolamine, AMPD etc.
This antiseptic can be: methyl parabens, propyl para-hydroxybenzoate phenoxyethanol, diazonium imidazolidinyl urea, iodopropynyl alcohol butyl meglumine acid fat etc.
This PH regulator can be: sodium hydroxide, triethanolamine, citric acid etc.
This vitamins can be: vitamin A, vitamin C, vitamin E, pantothenic acid, vitamin B3 and their derivant etc.
This plant extraction elite can be: Aloe, Radix Hamamelidis Mollis, Fructus Cucumidis sativi, Fructus Citri Limoniae, lavandula angustifolia, Flos Rosae Rugosae etc.
This antioxidant can be: tocopherols, dibenzylatiooluene, Butylated hydroxyanisole, gallate ester etc.
This antioxidant auxiliary agent can be: phosphonic acids, maleic acid, malonic acid, phytic acid, EDTA etc.
This skin moistening oils and fats comprises the conventional emollient in personal care articles field, comprises natural plant grease, synthetic ester oil and natural animal oils and fats and wax class emollient.
Tool of the present invention has the following advantages and Advantageous Effects:
Found by inventor's experimental study, the present invention, by by Glycyrrhiza glabra L. extract, whitening complex and peel of Citrus reticulata Blanco extract, during three kinds of component compound uses, can reach whitening effect safely and effectively, by consumer's feedback on probation, the expectation of consumer to the cosmetic product of whitening can be met.
Detailed description of the invention
Be described in further detail the present invention below by way of concrete preferred embodiment, single the present invention is not limited in following embodiment.Following percentage ratio is all weight percentage.
embodiment 1-3
A kind of whitening cosmetic compound, is made into whitening essence lotion, the content of its raw material components proportioning and reference examples raw material components proportioning, as shown in table 1 below.
Whitening essence lotion (the unit: % by weight) of table 1 embodiment 1-3 and reference examples 1-3
The process for making of whitening essence lotion can be expressed as follows:
Deionized water is put into production in pot, add with the pre-dispersed good HANSHENGJIAO of glycerol, hyaluronic acid, be warming up to 85 DEG C, insulated and stirred 20 minutes, open cooling water, be cooled to 45 DEG C, add that the Gan Guangcao that dissolved with 1.3-butanediol is fixed-90, whitening complex, peel of Citrus reticulata Blanco extract, essence/antiseptic; Stir 20 minutes, be cooled to room temperature, the qualified rear discharging of censorship, for subsequent use.
Composition 6-whitening complex wherein, its raw material components formula and content as shown in table 2 below.
The raw material components formula of table 2 whitening complex
| Ingredient names | Content (% by weight) |
| Water | 48.9930 |
| Butanediol | 48.7511 |
| Arbutin | 0.4750 |
| Citric acid | 0.4750 |
| Sodium sulfite | 0.4750 |
| Acetyl Tyrosine | 0.1425 |
| Aaron's beard extract | 0.1188 |
| Peony root extractive | 0.0855 |
| Aminopropanol ascorbic acid phosphoric acid esters | 0.04725 |
| Scutellariae,radix extract | 0.0428 |
| Glutathion | 0.0048 |
| Hydrolysis mirabalan | 0.3890 |
effect application test example
1, face's skin color evaluation is improved:
For confirming the improvement effect of skin complexion, test using 20-40 year healthy women 60 as object, these people are divided into 6 groups, often organize 10 people, use sample to each group, make experimenter be coated on whole face, apply 2 every day, coating used colorimeter (MinoltaCM-3500d) to measure the change (Δ L*) of the change of colour brightness in 4 weeks .4 weeks afterwards altogether, and in the present invention, L* value (brightness) is mainly used as index.L* value is corrected by standard edition, and in a part repeated measure 5 times or more, to measure the part of pigmentation uniformly.
Calculated according to following equation (1) by the skin color difference (Δ L*) applied between the sart point in time of each compositions and deadline point, the result calculated is in following table 3, meanwhile, the Δ L* value applied by comparative sample between contrast part is evaluated whitening effect.Δ L* value represents that pigmentation is obviously alleviated when being approximately 2, if it is above about 1.5, it can be judged as has whitening effect.
Equation (1): Δ L*=L* (carrying out test after 2 months)-L* is (before carrying out on-test
Table 3 reference examples 1-3 compares with the skin color difference Δ L* value of embodiment of the present invention 1-3
| Sample sets | ΔL* |
| Reference examples 1 | 0.01 |
| Reference examples 2 | 0.15 |
| Reference examples 3 | 0.55 |
| Embodiment 1 | 3.58 |
| Embodiment 2 | 4.12 |
| Embodiment 3 | 4.55 |
Found out by the result of table 3, Gan Guangcao is fixed-90, peel of Citrus reticulata Blanco extract, whitening complex three materials are when being used alone, desirable effect can not be reached, when three material combineds effect, can be judged to be that there is the effect obviously alleviating pigmentation and whitening.
embodiment 4-6
A kind of whitening cosmetic compound, is made into whitening emulsion, the content of its raw material components proportioning and reference examples raw material components proportioning, as shown in table 4 below.
Whitening emulsion (the unit: % by weight) of table 4 embodiment 4-6 and reference examples 4-6
The process for making of whitening emulsion can be expressed as follows:
1) deionized water is added kettle, drop into card ripple 941 under fast stirring, add the scattered hyaluronic acid of glycerol and HANSHENGJIAO after stirring, be warming up to 85 DEG C, insulated and stirred 20 minutes, for subsequent use;
2) cetearyl alcohol, ceteareth-25, squalane, Jojoba oil are dropped into oil phase pot, be warming up to 80 DEG C, insulated and stirred 20 minutes, for subsequent use;
3) by kettle and oil cauldron raw material suction emulsifying pot, high speed homogenization 10 minutes, insulated and stirred 20 minutes, be cooled to 45 DEG C, add triethanolamine, Gan Guangcao that 1.3-butanediol has dissolved is fixed-90, essence/antiseptic, stir 20 minutes, be cooled to room temperature, the qualified rear discharging of censorship, for subsequent use.
Composition 4-whitening complex wherein, its raw material components formula and content as shown in table 5.
The raw material components formula of table 5 whitening complex
| Ingredient names | Content (% by weight) |
| Water | 49.13 |
| Butanediol | 48 |
| Arbutin | 0.1 |
| Citric acid | 1 |
| Sodium sulfite | 0.5 |
| Acetyl Tyrosine | 0.5 |
| Aaron's beard extract | 0.2 |
| Peony root extractive | 0.01 |
| Aminopropanol ascorbic acid phosphoric acid esters | 0.1 |
| Scutellariae,radix extract | 0.4 |
| Glutathion | 0.05 |
| Hydrolysis mirabalan | 0.01 |
effect application test example
1, face's skin color evaluation is improved:
For confirming the improvement effect of skin complexion, test using 20-40 year healthy women 60 as object, these people are divided into 6 groups, often organize 10 people, use sample to each group, make experimenter be coated on whole face, apply 2 every day, coating used colorimeter (MinoltaCM-3500d) to measure the change (Δ L*) of the change of colour brightness in 4 weeks .4 weeks afterwards altogether, and in the present invention, L* value (brightness) is mainly used as index.L* value is corrected by standard edition, and in a part repeated measure 5 times or more, to measure the part of pigmentation uniformly.
Calculated according to following equation (1) by the skin color difference (Δ L*) applied between the sart point in time of each compositions and deadline point, the result calculated is in following table, meanwhile, the Δ L* value applied by comparative sample between contrast part is evaluated whitening effect.Δ L* represents when value is approximately 2, and pigmentation is obviously alleviated, if it is above about 1.5, it can be judged as has whitening effect.
Table 6 reference examples 4-6 compares with the skin color difference Δ L* value of embodiment of the present invention 4-6
By table 6, can find out that Gan Guangcao is fixed-90, whitening complex, peel of Citrus reticulata Blanco extract wherein two composite effects do not reach whitening effect, when the composite use of wherein three, there is the effect alleviating preferably pigmentation and whitening, and have the trend of increase along with the increase effect of three's use amount.
2, human body skin stimulates test:
The compositions of reference examples 4-6 and embodiment 4-6 be used for the experimenter of testing example 2 and continue after 2 months, between compositions, comparing the stimulation for skin.Often kind of compositions to skin irritant score from 1 (non-stimulated) to 5 (the highest stimulations).Following table 7 shows the average of compositions.
Table 7 reference examples 4-6 compares with the skin color difference Δ L* value of embodiment of the present invention 4-6
| Sample sets | Skin irritation |
| Reference examples 4 | 3.25 |
| Reference examples 5 | 2.98 |
| Reference examples 6 | 2.51 |
| Embodiment 4 | 1.10 |
| Embodiment 5 | 1.59 |
| Embodiment 6 | 1.25 |
As can be seen from the result of above-mentioned table 7, the compositions of reference examples 4-6 of the present invention and embodiment 4-6 has lower skin irritation, and safety is better.
The above, it is only preferred embodiment of the present invention, not any pro forma restriction is done to the present invention, therefore everyly do not depart from technical solution of the present invention content, the any simple modification done above embodiment according to technical spirit of the present invention, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.
Claims (10)
1. a whitening cosmetic compound, is characterized in that: by weight percentage, comprises following component:
The Glycyrrhiza glabra L. extract of 0.01-5.00%;
The whitening complex of 0.1-10.00%, wherein the composition of whitening complex is water, butanediol, arbutin, citric acid, sodium sulfite, Acetyl Tyrosine, aaron's beard extract, peony root extractive, aminopropanol ascorbic acid phosphoric acid esters, scutellariae,radix extract, glutathion, hydrolysis mirabalan;
The peel of Citrus reticulata Blanco extract of 0.01-10.00%;
The cosmetic substrate of 75.00-99.85%.
2. whitening cosmetic compound according to claim 1, is characterized in that: described Glycyrrhiza glabra L. extract is the flavonoid compound extracted from Glycyrrhiza glabra L., and its active component is glabridin-90.
3. whitening cosmetic compound according to claim 1, is characterized in that: the ratio that described whitening complex comprises each component is: water 40-50%, butanediol 40-50%, arbutin 0.1-1%, citric acid 0.1-1%, sodium sulfite 0.1-1%, Acetyl Tyrosine 0.1-1%, aaron's beard extract 0.01-0.5%, peony root extractive 0.01-0.5%, aminopropanol ascorbic acid phosphoric acid esters 0.001-0.1%, scutellariae,radix extract 0.01-0.5%, glutathion 0.001-0.1%, hydrolysis mirabalan 0.01-0.5%.
4. whitening cosmetic compound according to claim 3, is characterized in that: the ratio that described whitening complex comprises each component is: water 48.9930%, butanediol 48.7511%, arbutin 0.4750%, citric acid 0.4750%, sodium sulfite 0.4750%, Acetyl Tyrosine 0.1425%, aaron's beard extract 0.1188%, peony root extractive 0.0855%, aminopropanol ascorbic acid phosphoric acid esters 0.04725%, scutellariae,radix extract 0.0428%, paddy Guang are sweet 0.0048%, hydrolysis mirabalan 0.3890%.
5. whitening cosmetic compound according to claim 1, is characterized in that: described Glycyrrhiza glabra L. extract accounts for the 0.1-2.0% of cosmetic composition.
6. whitening cosmetic compound according to claim 1, is characterized in that: described whitening complex accounts for the 0.5-5% of cosmetics whitening cosmetic compound weight, is preferably 2-5%.
7. whitening cosmetic compound according to claim 1, is characterized in that: described its effective ingredient of peel of Citrus reticulata Blanco extract is flavonoid, has O-polymethoxyflavone structure.
8. whitening cosmetic compound according to claim 7, is characterized in that: described peel of Citrus reticulata Blanco extract adopts following methods to obtain:
A) by after peel of Citrus reticulata Blanco pure water, drying is carried out.After being pulverized by dewatered peel of Citrus reticulata Blanco, utilize merceration extraction method at ambient temperature, propose effective ingredient through 40-48 hour;
B) after the content extracted utilizes 250um object screen cloth once to filter, by centrifugalize, supernatant is obtained; Again above-mentioned supernatant is filtered in order with 3um, 1um, 0.5um object filter paper afterwards;
C) add 1.3-butanediol, then obtain peel of Citrus reticulata Blanco extract with after 0.2-0.3um object filter paper filtering.
9. whitening cosmetic compound according to claim 7, is characterized in that: described peel of Citrus reticulata Blanco extract accounts for cosmetics weight 0.5-5.0%.
10. whitening cosmetic compound according to claim 1, it is characterized in that: described cosmetic substrate comprises water-soluble macromolecule, semi-synthetic water soluble polymer, Inorganic water-soluble macromolecule, UV absorbent, metal ion chelation agent, lower alcohol, polyhydric alcohol, monosaccharide, oligosaccharide, polysaccharide, aminoacid, organic amine, antiseptic, PH regulator, vitamins, plant extraction elite, antioxidant, antioxidation auxiliary agent, spice, water, skin moistening oils and fats etc., these compositions can be one or more combinations.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510900820.0A CN105411931A (en) | 2015-12-09 | 2015-12-09 | Whitening cosmetic composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510900820.0A CN105411931A (en) | 2015-12-09 | 2015-12-09 | Whitening cosmetic composition |
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Cited By (17)
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| CN105769699A (en) * | 2016-04-15 | 2016-07-20 | 广州宝生堂化妆品有限公司 | Skin care composition with skin whitening function |
| CN105919828A (en) * | 2016-07-07 | 2016-09-07 | 广州莱丽奇生物科技有限公司 | Whitening and freckle-lightening composition, as well as preparation method and application thereof |
| CN106309257A (en) * | 2016-11-02 | 2017-01-11 | 珍尔姿（广州）化妆品有限公司 | Instant-cooling gel moisturizing essence |
| CN106309272A (en) * | 2016-08-24 | 2017-01-11 | 广东芭薇生物科技股份有限公司 | Whitening cream and preparing method thereof |
| CN106361636A (en) * | 2016-09-19 | 2017-02-01 | 广东丸美生物技术股份有限公司 | Skincare composition and application thereof in skin whitening |
| CN107456412A (en) * | 2016-06-03 | 2017-12-12 | 广州科颜氏药妆生物科技研发中心（有限合伙） | A kind of cosmetic material that can allow the light spot of skin-whitening |
| CN107753343A (en) * | 2017-11-13 | 2018-03-06 | 肌本美（深圳）科技有限公司 | A kind of composition for being used to improve skin moisture and adjust the colour of skin |
| CN108042412A (en) * | 2017-11-17 | 2018-05-18 | 高源� | A kind of Whitening, spot Essence and preparation method thereof |
| CN108158971A (en) * | 2018-03-21 | 2018-06-15 | 通化百泉化妆品有限公司 | A kind of ginseng U.S. face film and preparation method |
| CN108498413A (en) * | 2018-07-05 | 2018-09-07 | 上海新高姿化妆品有限公司 | A kind of cosmetic composition containing whitening compound |
| CN108542831A (en) * | 2018-07-05 | 2018-09-18 | 上海新高姿化妆品有限公司 | A kind of whitening and skin-protecting water and preparation method thereof with collaboration whitening effect |
| CN108578300A (en) * | 2018-07-05 | 2018-09-28 | 上海新高姿化妆品有限公司 | A kind of skin-care gel and preparation method thereof with collaboration whitening effect |
| CN108619033A (en) * | 2018-07-05 | 2018-10-09 | 上海新高姿化妆品有限公司 | Whitening and skin-protecting essence and preparation method thereof with collaboration whitening effect |
| CN108653092A (en) * | 2018-07-05 | 2018-10-16 | 上海新高姿化妆品有限公司 | A kind of cosmetic composition with collaboration whitening effect |
| CN108653093A (en) * | 2018-07-05 | 2018-10-16 | 上海新高姿化妆品有限公司 | A kind of cosmetic composition with whitening skin lightening |
| CN109646324A (en) * | 2019-02-25 | 2019-04-19 | 高源� | The compact whitening spot-relieving cream and preparation method thereof that collagen composite plant extracts |
| CN113952267A (en) * | 2021-10-19 | 2022-01-21 | 上海润之素生物科技有限公司 | Composition with light-line brightening effect and application of composition in cosmetics |
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Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105769699A (en) * | 2016-04-15 | 2016-07-20 | 广州宝生堂化妆品有限公司 | Skin care composition with skin whitening function |
| CN107456412A (en) * | 2016-06-03 | 2017-12-12 | 广州科颜氏药妆生物科技研发中心（有限合伙） | A kind of cosmetic material that can allow the light spot of skin-whitening |
| CN105919828B (en) * | 2016-07-07 | 2019-06-21 | 广州莱丽奇生物科技有限公司 | A kind of Whitening, spot composition, preparation method and applications |
| CN105919828A (en) * | 2016-07-07 | 2016-09-07 | 广州莱丽奇生物科技有限公司 | Whitening and freckle-lightening composition, as well as preparation method and application thereof |
| CN106309272A (en) * | 2016-08-24 | 2017-01-11 | 广东芭薇生物科技股份有限公司 | Whitening cream and preparing method thereof |
| CN106361636A (en) * | 2016-09-19 | 2017-02-01 | 广东丸美生物技术股份有限公司 | Skincare composition and application thereof in skin whitening |
| CN106361636B (en) * | 2016-09-19 | 2019-12-31 | 广东丸美生物技术股份有限公司 | Skin care composition and application thereof in whitening and brightening skin |
| CN106309257A (en) * | 2016-11-02 | 2017-01-11 | 珍尔姿（广州）化妆品有限公司 | Instant-cooling gel moisturizing essence |
| CN107753343A (en) * | 2017-11-13 | 2018-03-06 | 肌本美（深圳）科技有限公司 | A kind of composition for being used to improve skin moisture and adjust the colour of skin |
| CN108042412A (en) * | 2017-11-17 | 2018-05-18 | 高源� | A kind of Whitening, spot Essence and preparation method thereof |
| CN108158971A (en) * | 2018-03-21 | 2018-06-15 | 通化百泉化妆品有限公司 | A kind of ginseng U.S. face film and preparation method |
| CN108542831A (en) * | 2018-07-05 | 2018-09-18 | 上海新高姿化妆品有限公司 | A kind of whitening and skin-protecting water and preparation method thereof with collaboration whitening effect |
| CN108619033A (en) * | 2018-07-05 | 2018-10-09 | 上海新高姿化妆品有限公司 | Whitening and skin-protecting essence and preparation method thereof with collaboration whitening effect |
| CN108653092A (en) * | 2018-07-05 | 2018-10-16 | 上海新高姿化妆品有限公司 | A kind of cosmetic composition with collaboration whitening effect |
| CN108653093A (en) * | 2018-07-05 | 2018-10-16 | 上海新高姿化妆品有限公司 | A kind of cosmetic composition with whitening skin lightening |
| CN108578300A (en) * | 2018-07-05 | 2018-09-28 | 上海新高姿化妆品有限公司 | A kind of skin-care gel and preparation method thereof with collaboration whitening effect |
| CN108498413A (en) * | 2018-07-05 | 2018-09-07 | 上海新高姿化妆品有限公司 | A kind of cosmetic composition containing whitening compound |
| CN108578300B (en) * | 2018-07-05 | 2020-01-31 | 上海新高姿化妆品有限公司 | skin care gel with synergistic whitening effect and preparation method thereof |
| CN109646324A (en) * | 2019-02-25 | 2019-04-19 | 高源� | The compact whitening spot-relieving cream and preparation method thereof that collagen composite plant extracts |
| CN113952267A (en) * | 2021-10-19 | 2022-01-21 | 上海润之素生物科技有限公司 | Composition with light-line brightening effect and application of composition in cosmetics |
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