CN105380870A - Toning lotion with efficacy of repairing cuticle and a preparation method of toning lotion - Google Patents
Toning lotion with efficacy of repairing cuticle and a preparation method of toning lotion Download PDFInfo
- Publication number
- CN105380870A CN105380870A CN201511029242.4A CN201511029242A CN105380870A CN 105380870 A CN105380870 A CN 105380870A CN 201511029242 A CN201511029242 A CN 201511029242A CN 105380870 A CN105380870 A CN 105380870A
- Authority
- CN
- China
- Prior art keywords
- astringent
- skin
- water
- horny layer
- layer effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to toning lotion with efficacy of repairing cuticle. The toning lotion is prepared from the following components in percentage by weight: 15 to 50 percent of plant flower water, 5 to 20 percent of moisturizer, 0.5 to 10 percent of skin conditioner and 0.1 to 1 percent of preservative. The invention also discloses a preparation method of the toning lotion with the efficacy of repairing cuticle. The toning lotion provided by the invention is reasonable in component formula, synergistic interaction is realized, the water content of skin is effectively promoted, skin itchiness is relieved, pathogenic dermatophyte and bacteria are effectively inhibited, the replacement of deep skin cells is stimulated, injured tissues are helped to heal, the skin is compacted, and skin immunity is effectively improved.
Description
Technical field
The invention belongs to cosmetic field, more particularly, is a kind ofly have astringent repairing horny layer effect and preparation method thereof.
Background technology
Excessive environmental pollution and erratic life style make numerous people moving in city endure the puzzlement of skin sensitivity symptom to the fullest extent, frequently there is general red, heating, pruritus, the uncomfortable phenomenon such as twinge and erythema in skin, mainly horny layer of epidermis is impaired and cause the immunity degradation of skin, cannot resist caused by extraneous stimulation.Although Loratadine can be treated effectively when time dermatitis symptom, dermatitis still can recurrent exerbation.
In current cosmetic industry, usually adopt the use amount reducing zest raw material or add synthesis anti-sensitizer to alleviate skin sensitivity, but this way fundamentally can not solve the problem of skin fragility.
Astringent is a kind of liquid skin protection cosmetics, wherein containing a large amount of water solublity nutritional labeling, to be easily absorbed by the skin and clearly free of a burden, have clean, moist, soft, releive and the effect such as conditioning.Therefore be necessary to attempt in astringent, add natural plant flowers water and natural plant extracts; astringent is made both to be applicable to the sensitivity skin life-time service of horny layer fragility; effective raising skin immunity and the impaired cutin of reparation; scalable moisture of skin and play nutrition and protective effect to skin again, fundamentally alleviates skin sensitivity symptom.
Summary of the invention
The present invention is directed to the deficiencies in the prior art part, provide a kind of and there is the astringent repairing horny layer effect.
There is described in the second object of the present invention is to provide the preparation method of the astringent repairing horny layer effect.
For solving above-mentioned technical problem, the present invention adopts following technical scheme:
There is the astringent repairing horny layer effect, making by comprising following weight percent composition:
component | percentage by weight (%) |
plant flowers water | 15 ~ 50 |
wetting agent | 5 ~ 20 |
skin conditioning agent | 0.5 ~ 10 |
antiseptic | 0.1 ~ 1. |
Preferably, described in there is the astringent repairing horny layer effect, make by comprising following weight percent composition:
component | percentage by weight (%) |
plant flowers water | 15 ~ 30 |
wetting agent | 5 ~ 15 |
skin conditioning agent | 1 ~ 5 |
antiseptic | 0.4 ~ 1. |
Preferably, described in there is the astringent repairing horny layer effect, make by comprising following weight percent composition:
component | percentage by weight (%) |
plant flowers water | 20 ~ 25 |
wetting agent | 5 ~ 10 |
skin conditioning agent | 3 ~ 5 |
antiseptic | 0.4 ~ 1. |
Preferably, described in there is the astringent repairing horny layer effect, make by comprising following weight percent composition:
Above-mentioned have in the astringent formula repairing horny layer effect, and surplus is deionized water mainly, also can add other required active component simultaneously.
Preferably, described plant flowers water is the mixing of more than three kinds in lavender flower water, rose wate, bitter aqua aurantii florum, horsewhip showy flowers of herbaceous plants water, Flos Jasmini flower water.
Plant flowers water, also known as hydrosol, formal name used at school is crystal's oil, a kind of 100% saturated distillation stock solution separated when refining quintessence oil, a kind of side-product of quintessence oil, wherein containing have an appointment 0.3 ~ 0.5% derived essential oil outside, also containing the whole water-soluble substances of plant.
Wherein lavender flower water (Lavenderwater) is lavender flower water distillate, it is water white clear liquid, at the saturated hydrosol refining separate from fresh lavandula angustifolia lobe in lavandula angustifolia (LAVANDULAANGUSTIFOLIA) oily process a kind of 100%, containing water soluble ingredients such as multiple tannin, protein, plant sugars.
Wherein Flos Rosae Rugosae (ROSARUGOSA) Hua Shui is when distilling Flos Rosae Rugosae (ROSARUGOSA) caul-fat, the aqueous solution distillated, this aqueous solution contain 0.02 ~ 0.03% Flos Rosae Rugosae quintessence oil and Flos Rosae Rugosae in the aqueous soluble active constituent such as protein, tannin, cyclic peptide.
Wherein bigarabe (CITRUSAURANTIUMAMARA) Hua Shui is the saturated hydrosol of separate in the process of distillation extraction bigarabe (CITRUSAURANTIUMAMARA) caul-fat a kind of 100%, containing compositions such as citronellol, linalool, nerol, geraniol and several amino acids.
Wherein Herba Verbenae (VERBENAOFFICINALIS) Hua Shui is the saturated hydrosol of separate in distillation extraction Herba Verbenae (VERBENAOFFICINALIS) oily process a kind of 100%, containing verbenalin, tannin, volatilization wet goods composition.
Wherein Flos Jasmini (JASMINUMOFFICINALE) Hua Shui is the saturated hydrosol of separate in distillation extraction Flos Jasmini (JASMINUMOFFICINALE) oily process a kind of 100%, containing compositions such as benzyl acetate, linalool, jasmones.
Preferably, described wetting agent is the mixing of more than three kinds in glycerol, 1,3-PD, 1,2-pentanediol, butanediol, Xylitol-based glucoside, xylitol, anhydro xylitol, biological carbohydrate gum-1, hyaluronate sodium.
Preferably, described skin conditioning agent is one or more the mixing in Herba Centellae extract, althaea root extract, golden yellow camomile extract.
Wherein Herba Centellae (CENTELLAASIATICA) extract is the extract of Herba Centellae (centella), can choose the Herba Centellae extract that IDBIO company produces, mainly containing Asiaticoside, and asiaticoside isoreactivity composition.
Wherein Althaea officinalis L. (ALTHAEAOFFICINALIS) root extract is the root extract of Malvaceae plant amedica Althaea rosea (L.) Cavan. (Althaeaofficinalis), can choose the althaea root extract that IDBIO company produces.
Wherein golden yellow Flos Matricariae chamomillae (CHRYSANTHELLUMINDICUM) extract is extracted by golden yellow Flos Matricariae chamomillae (Chrysanthellumindicum), the composition contained is mainly apigenin, can choose the golden yellow camomile extract that IDBIO company produces.
Preferably, described antiseptic is one or more the mixing in gluconic acid lactone, sodium benzoate, potassium sorbate.
The component that the present invention adopts at plant flowers water and skin conditioning agent is the natural plant composition of European Union ECOCERT international ecological certification or the natural plant composition of French ecology and organic skin care products qualification organization (COSMEBIO) certification.
Have a preparation method for the astringent repairing horny layer effect, the step comprised is as follows:
(1) wetting agent is added in agitated kettle by formula consumption, be heated to 60 ~ 80 DEG C, be stirred to mix homogeneously;
(2) treating that temperature is down to 35 ~ 45 DEG C, then add plant flowers water and skin conditioning agent respectively in agitated kettle by formula consumption, stirring to dissolving completely;
(3) in agitated kettle, add antiseptic by formula consumption, be stirred to mix homogeneously;
(4) take a sample to check, qualified rear filtration discharging, control ph is 5 ~ 7.
Preferably, in step (1), add deionized water, then add wetting agent.
Compared with prior art, the present invention has following beneficial effect: reasonable component formula, Synergistic; Only use natural botanical source composition to repair cuticular damage, do not use the chemosynthesis anti-sensitizer in traditional repairing type cosmetics; The present invention based on anti-inflammation and sterilization, help damaged tissues healing and improve skin immunity, with replenishing water and preserving moisture with releive antipruritic to be auxiliary, fundamentally to alleviate the condition susceptible caused because horny layer is impaired.
Specific embodiment
In order to set forth content of the present invention better, be described with some preferably specific embodiments below.But these specific embodiments are just in order to illustrate content of the present invention, instead of limit content of the present invention.
Principle explanation
1. about the plant flowers water in formula of the present invention:
Lavender flower glassware for drinking water has replenishing water and preserving moisture, conditioning skin quality, convergence pore, the effect of bacteria growing inhibiting, and can promote that comedo or minor cut or wound heal rapidly, accelerates cell regeneration.
Rose wate has comprehensive conditioning effect, and can moisturizing to cell interior, fundamentally solve xerosis cutis problem, can also eliminate red blood streak rapidly, reduce skin sensitivity, whitening highlights, and strengthens skin vigor.
Bitter aqua aurantii florum can supplement moisture of skin fast, increases cytoactive and promotes cell regeneration, strengthening skin elasticity, eliminating the colour of skin uneven and obscure.
Horsewhip showy flowers of herbaceous plants water energy inducing diuresis to remove edema, promoting blood circulation to remove blood stasis, has anti-inflammatory analgetic effect.
Flos Jasmini flower water can detoxify parasite killing, is usually used in the treating for skin disease such as scabies, zona shingles clinically.
2. about the wetting agent in formula of the present invention:
Xylitol, biological carbohydrate gum-1,1,2-pentanediol, hyaluronate sodium, 1,3-PD and glycerol etc. are the wetting agents with excellent long-acting moisturizing lock water effect, and giving skin Shu Min protects, and brings joyful sense to skin.
3. about the skin conditioning agent in formula of the present invention:
Herba Centellae extract can anti-inflammation, subduing swelling and detoxicating and dispel abscess, deep skin cell can be stimulated to substitute, help impaired organization healing and consolidation skin.
Althaea root extract energy horny layer softening, regulates water oil balance, keeps skin to moisten lastingly, effectively releive calm.
Golden yellow camomile extract can soft and protection skin, and calmness is pacified, itch-stopping bactericidal, is applicable to dryness and sensitivity skin uses.
4. about the antiseptic in formula of the present invention:
Gluconic acid lactone, potassium sorbate and sodium benzoate are plant origin antiseptic, and character gentleness does not stimulate.
Share under the proportioning that above component is recorded in the present invention, effective lifting moisture content of skin, to releive skin pruritus, suppress pathogenic dermatophytes and antibacterial, deep skin cell is stimulated to substitute, help damaged tissues healing and consolidation skin, improve skin immunity, fundamentally alleviate the condition susceptible caused because horny layer is impaired.
Embodiment 1
There is the astringent repairing horny layer effect, be made up of the weight percent composition in following formula table:
Preparation method is as follows:
(1) under the condition of room temperature, hyaluronate sodium is disperseed in advance in glycerol and 1,3-PD, be dissolved in aqueous phase;
(2) rose wate, bitter aqua aurantii florum, lavender flower water, Xylitol-based glucoside, althaea root extract, biological carbohydrate gum-1, Herba Centellae extract and 1,2-pentanediol being added in aqueous phase respectively, stirring to dissolving completely;
(3) sodium benzoate is dissolved to transparent in advance in water, then drops in aqueous phase, be stirred to completely evenly;
(4) check pH value, control ph is 6.5, and after qualified, 200 orders filter discharging.
The rose wate of the present embodiment: bitter aqua aurantii florum: lavender flower water=2:2:1; Althaea root extract: Herba Centellae extract=1:1; 1,3-PD: Xylitol-based glucoside: glycerol: biological carbohydrate gum-1:1,2-pentanediol: hyaluronate sodium=7:3:2:0.5:0.5:0.05; Extraordinary effect can be played like this, specifically see beneficial effect test below; This effect also can obtain identical checking in other embodiments.
Embodiment 2
There is the astringent repairing horny layer effect, be made up of the weight percent composition in following formula table:
Component | Percentage by weight (%) |
Horsewhip showy flowers of herbaceous plants water | 10 |
Bitter aqua aurantii florum | 5 |
1,3-PD | 7 |
Lavender flower water | 10 |
Xylitol | 3 |
Althaea root extract | 1 |
Golden yellow camomile extract | 1 |
Glycerol | 2 |
Biological carbohydrate gum-1 | 0.5 |
Herba Centellae extract | 3 |
Gluconic acid lactone | 0.7 |
1,2-pentanediol | 0.5 |
Hyaluronate sodium | 0.02 |
Deionized water | To 100 |
Preparation method is as follows:
(1) under the condition of room temperature, hyaluronate sodium is disperseed in advance in glycerol and 1,3-PD, be dissolved in aqueous phase;
(2) horsewhip showy flowers of herbaceous plants water, bitter aqua aurantii florum, lavender flower water, xylitol, althaea root extract, biological carbohydrate gum-1, Herba Centellae extract, golden yellow camomile extract and 1,2-pentanediol being added in aqueous phase respectively, stirring to dissolving completely;
(3) gluconic acid lactone is dissolved to transparent in advance in water, then drops in aqueous phase, be stirred to completely evenly;
(4) check pH value, control ph is 6, and after qualified, 200 orders filter discharging.
The horsewhip showy flowers of herbaceous plants water of the present embodiment: bitter aqua aurantii florum: lavender flower water=2:1:2; Althaea root extract: golden yellow camomile extract: Herba Centellae extract=1:1:3; 1,3-PD: xylitol: glycerol: biological carbohydrate gum-1:1,2-pentanediol: hyaluronate sodium=7:3:2:0.5:0.5:0.02; Extraordinary effect can be played like this, specifically see beneficial effect test below; This effect also can obtain identical checking in other embodiments.
Embodiment 3
There is the astringent repairing horny layer effect, be made up of the weight percent composition in following formula table:
Component | Percentage by weight (%) |
Lavender flower water | 10 |
Bitter aqua aurantii florum | 5 |
Rose wate | 5 |
Flos Jasmini flower water | 5 |
1,3-PD | 5 |
Butanediol | 3 |
Althaea root extract | 3 |
Glycerol | 1 |
Biological carbohydrate gum-1 | 2 |
Herba Centellae extract | 1 |
Gluconic acid lactone | 0.3 |
Anhydro xylitol | 0.4 |
Potassium sorbate | 0.2 |
Hyaluronate sodium | 0.02 |
Deionized water | To 100 |
Preparation method is as follows:
(1) under the condition of room temperature, hyaluronate sodium is disperseed in advance in glycerol and 1,3-PD, be dissolved in aqueous phase;
(2) rose wate, bitter aqua aurantii florum, lavender flower water, Flos Jasmini flower water, anhydro xylitol, althaea root extract, biological carbohydrate gum-1, Herba Centellae extract and butanediol being added in aqueous phase respectively, stirring to dissolving completely;
(3) gluconic acid lactone and potassium sorbate are dissolved to transparent in advance in water, then drop in aqueous phase, be stirred to completely evenly;
(4) check pH value, control ph is 6, and after qualified, 200 orders filter discharging.
The lavender flower water of the present embodiment: bitter aqua aurantii florum: rose wate: Flos Jasmini flower water=2:1:1:1; Althaea root extract: Herba Centellae extract=3:1; 1,3-PD: butanediol: glycerol: biological carbohydrate gum-1: anhydro xylitol: hyaluronate sodium=5:3:1:2:0.4:0.02; Can play extraordinary effect like this, specifically see beneficial effect test below, this effect also can obtain identical checking in other embodiments.
In formula of the present invention, the adjustment of pH value can use acid conventional in cosmetic industry or alkali raw material.
Moisture-keeping efficacy evaluation test
Respectively the astringent of embodiment 1 ~ 3 is carried out following moisture-keeping efficacy evaluation test, this moisture-keeping efficacy evaluation test comprises skin moisture content testing experiment and skin moisture loss (TEWL) testing experiment:
The instrument of skin moisture content testing experiment is the skin moisture content Corneometer test probe that German Courage+Khazaka company (German CK company) manufactures.
The instrument of skin moisture loss (TEWL) testing experiment is skin moisture loss (TEWL) TewameterTM300 test probe that German Courage+Khazaka company (German CK company) manufactures.
What skin moisture content test adopted is universally acknowledged
method-capacitance method.The function of skin moisture loss TEWL to assessment skin moisture protective layer is very important parameter, has been widely recognized in the world.Protective layer of skin is more intact, and the content of moisture content will be higher, and the numerical value of skin moisture loss TEWL is lower.Whether the defencive function of moisture of skin test energy Timeliness coverage skin is destroyed.
Choose responsive skin crowd (sensation of pricking adds up >=3 points of persons) 120, the age, men and women half and half at 20 ~ 45 years old.Be divided into 3 groups at random, often organize 20 male, 20 women.Recipient site can not use any product (cosmetics or topical drug or health product for oral administration) for first 15 days.Before test, require that experimenter cleans facial area and within 2 hours, enters temperature 22 ± 1 DEG C after cleaning, sit quietly in the constant temperature and humidity room of humidity 50 ± 5% 30min, and keep relaxation state.
Carry out half of face test by random table in test, the side face often organizing experimenter smears the astringent of embodiment 1 or 2 or 3, and opposite side face is blank (use deionized water).The left and right nasolabial fold part choosing experimenter carries out skin moisture content measuring and moisture loss (TEWL) test, gets the data (D0) of meansigma methods as nasolabial fold water content and the data (D0) of nasolabial fold skin moisture loss (TEWL) of 3 values.
After test terminates, the side face often organizing experimenter continues the astringent smearing embodiment 1 or 2 or 3, opposite side face is blank (use deionized water), sooner or later carry out for 2 times smearing astringent every day on request, 28 days on probation continuously, and require that the 14th day (D14) and the 28th day (D28) of test pays a return visit.
The result of moisture-keeping efficacy evaluation test is as shown in the table:
The moistening effect that embodiment 2 compares embodiment 1 and 3 is more excellent, i.e. horsewhip showy flowers of herbaceous plants water: bitter aqua aurantii florum: lavender flower water=2:1:2; Althaea root extract: golden yellow camomile extract: Herba Centellae extract=1:1:3; 1,3-PD: xylitol: glycerol: biological carbohydrate gum-1:1,2-pentanediol: what hyaluronate sodium=7:3:2:0.5:0.5:0.02 obtained has the astringent moisture-keeping efficacy the best of repairing horny layer effect.
Facial area lactic acid stimulates efficacy assessment test
Respectively the astringent of embodiment 1 ~ 3 is carried out following facial area lactic acid and stimulates efficacy assessment test:
Half of face test is carried out by random table in test, the side face often organizing experimenter smears the astringent of embodiment 1 or 2 or 3, opposite side face is blank (use deionized water), experimenter's nasolabial fold position is selected to test, 10% lactic acid solution 50ul is dropped on the monolayer filter paper that diameter is 0.8cm, respectively at 3min, 4min and 5min inquires experimenter's sensation of pricking, being undertaken marking by 4 point-scores, (0 is divided into and does not have sensation of pricking, 1 is divided into slight twinge, 2 are divided into moderate twinge, 3 are divided into severe twinge), the scoring of record experimenter stimulates scoring (D0) as this side lactic acid.
After test terminates, the side face often organizing experimenter continues the astringent smearing embodiment 1 or 2 or 3, opposite side face is blank (use deionized water), sooner or later carry out product for 2 times every day on request to smear, 28 days on probation continuously, and require that the 14th day (D14) and the 28th day (D28) of test pays a return visit.
Facial area lactic acid stimulates the result of efficacy assessment test as shown in the table:
Moisture-keeping efficacy evaluation test and facial area lactic acid stimulate the result of efficacy assessment test to show, the colored aquation adornment glassware for drinking water of embodiment 1 ~ 3 has obvious effect difference, the astringent of embodiment 1 ~ 3 has certain repair to keratodermatitis, effectively can increase the water content of keratodermatitis, reduce the moisture loss that keratodermatitis is external, effectively can to releive again the sensitivity of skin simultaneously, to reduce lactic acid effect of stimulation.
Antimicrobial efficacy assessment is tested
Microorganic adhesion floating in air can affect the performance of skin normal function in skin surface, rubescent heating, pruritus or even infection and acne can be caused, this test to the inhibition had compared with the staphylococcus aureus of High pathogenicity as the index of sterilizing ability.
1, test instrunment
The HVE250 type autoclave sterilizer that HIRAYA-MA company of Japan manufactures; The BHS-1300 II A/B3 biologic cleanliness safety cabinet that Purifying Equipment Co., Ltd., Suzhou manufactures.
2, method of testing
Respectively the astringent of embodiment 1 ~ 3 is carried out the test of Antimicrobial efficacy assessment, half of face test is carried out by random table in test, the side face often organizing experimenter smears the astringent of embodiment 1 or 2 or 3, opposite side face is blank (use deionized water), bacterium is got with nasolabial fold side, the left and right cheek of sterilized sampler scraping experimenter respectively, get the data of meansigma methods as 0h of 2 values, smear respectively at the one-sided use sample of left and right cheek by random table after the clean skin of experimenter, and respectively at 30min after smearing, 2h, 4h, 6h, the each time point of 8h gets bacterium, use EasyStamp to cultivate to cultivate 48 hours based on 37 DEG C, the pink S. aureus colonies that media surface produces is counted.
The result of Antimicrobial efficacy assessment test is as shown in the table:
Result shows, the astringent of embodiment 1 ~ 3 effectively can suppress the growth of staphylococcus aureus, has good bactericidal antiphlogistic effect.
The result of above three tests shows, the lavender flower water of embodiment 3: bitter aqua aurantii florum: rose wate: Flos Jasmini flower water=2:1:1:1; Althaea root extract: Herba Centellae extract=3:1; 1, ammediol: butanediol: glycerol: biological carbohydrate gum-1: anhydro xylitol: what hyaluronate sodium=5:3:1:2:0.4:0.02 obtained have, and to repair the astringent effect of horny layer effect optimum, the proportioning simultaneously also illustrating between plant flowers water of the present invention and skin conditioning agent component proportion and each component directly affect astringent moisturizing, reduce lactic acid stimulate, suppress microorganism etc. in effect difference.
In sum, the present invention has the astringent repairing horny layer effect effectively can promote moisture content of skin, to releive skin sensitivity, suppress pathogenic dermatophytes and bacterial growth, deep skin cell is stimulated to substitute, repair damaged Stratum Corneum, strengthen skin resistivity to external world, fundamentally alleviate skin sensitivity symptom.
Above-described embodiment is the present invention's preferably embodiment; but embodiments of the present invention are not restricted to the described embodiments; change, the modification done under other any does not deviate from spirit of the present invention and principle, substitute, combine, simplify; all should be equivalent replacement mode, be included within protection scope of the present invention.
Claims (9)
1. there is the astringent repairing horny layer effect, it is characterized in that, be made up of the component comprising following percentage by weight: plant flowers water 15 ~ 50, wetting agent 5 ~ 20, skin conditioning agent 0.5 ~ 10, antiseptic 0.1 ~ 1.
2. a kind of astringent with reparation horny layer effect according to claim 1, is characterized in that, be made up of the component comprising following percentage by weight: plant flowers water 15 ~ 30, wetting agent 5 ~ 15, skin conditioning agent 1 ~ 5, antiseptic 0.4 ~ 1.
3. a kind of astringent with reparation horny layer effect according to claim 1, is characterized in that, be made up of the component comprising following percentage by weight: plant flowers water 20 ~ 25, wetting agent 5 ~ 10, skin conditioning agent 3 ~ 5, antiseptic 0.4 ~ 1.
4. a kind of astringent with reparation horny layer effect according to claim 1, is characterized in that, be made up of the component comprising following percentage by weight: plant flowers water 20 ~ 25, wetting agent 5 ~ 10, skin conditioning agent 3 ~ 5, antiseptic 0.4 ~ 0.7.
5. a kind of astringent with reparation horny layer effect according to claim 1, is characterized in that: described plant flowers water is the mixing of more than three kinds in lavender flower water, rose wate, bitter aqua aurantii florum, horsewhip showy flowers of herbaceous plants water, Flos Jasmini flower water.
6. a kind of astringent with reparation horny layer effect according to claim 1, it is characterized in that: described wetting agent is glycerol, 1, the mixing of more than three kinds in ammediol, 1,2-pentanediol, butanediol, Xylitol-based glucoside, xylitol, anhydro xylitol, biological carbohydrate gum-1, hyaluronate sodium.
7. a kind of astringent with reparation horny layer effect according to claim 1, is characterized in that: described skin conditioning agent is one or more the mixing in Herba Centellae extract, althaea root extract, golden yellow camomile extract.
8. a kind of astringent with reparation horny layer effect according to claim 1, is characterized in that: described antiseptic is one or more the mixing in gluconic acid lactone, sodium benzoate, potassium sorbate.
9. a kind of preparation method with the astringent repairing horny layer effect according to claim 1, it is characterized in that, the step comprised is as follows:
(1) wetting agent is added in agitated kettle by formula consumption, be heated to 60 ~ 80 DEG C, be stirred to mix homogeneously;
(2) treating that temperature is down to 35 ~ 45 DEG C, then add plant flowers water and skin conditioning agent respectively in agitated kettle by formula consumption, stirring to dissolving completely;
(3) in agitated kettle, add antiseptic by formula consumption, be stirred to mix homogeneously;
(4) take a sample to check, qualified rear filtration discharging, control ph is 5 ~ 7.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201511029242.4A CN105380870A (en) | 2015-12-30 | 2015-12-30 | Toning lotion with efficacy of repairing cuticle and a preparation method of toning lotion |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201511029242.4A CN105380870A (en) | 2015-12-30 | 2015-12-30 | Toning lotion with efficacy of repairing cuticle and a preparation method of toning lotion |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105380870A true CN105380870A (en) | 2016-03-09 |
Family
ID=55414053
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201511029242.4A Pending CN105380870A (en) | 2015-12-30 | 2015-12-30 | Toning lotion with efficacy of repairing cuticle and a preparation method of toning lotion |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105380870A (en) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106074353A (en) * | 2016-06-28 | 2016-11-09 | 广东轻工职业技术学院 | A kind of solid cosmetic water and production technology thereof |
CN106333889A (en) * | 2016-08-24 | 2017-01-18 | 登封市科创商务咨询有限公司 | Natural organic firming lotion |
CN106511171A (en) * | 2016-12-06 | 2017-03-22 | 广州聚禅现代农业研究院有限公司 | Amaranth polysaccharide-containing beautifying lotion |
CN106606450A (en) * | 2016-12-23 | 2017-05-03 | 惠州市七分妆化妆品有限公司 | Plant nutrient water |
CN106726654A (en) * | 2017-04-06 | 2017-05-31 | 湖南御家化妆品制造有限公司 | A kind of xylitol moisture-keeping composition and its application in cosmetics |
CN107007511A (en) * | 2017-05-23 | 2017-08-04 | 广州珈源日化用品有限公司 | Cosmetic composition with hormone-healing face effect and preparation method and application thereof |
CN107362078A (en) * | 2017-06-28 | 2017-11-21 | 权启康 | A kind of Chinese herbal medicine toner |
CN107375106A (en) * | 2017-08-25 | 2017-11-24 | 漳浦彩露华化妆品有限公司 | A kind of moist water and preparation method thereof |
CN107669532A (en) * | 2016-12-12 | 2018-02-09 | 青岛大学 | Suncream |
CN107998022A (en) * | 2017-12-19 | 2018-05-08 | 武汉北度生物科技有限公司 | A kind of antioxidation cosmetic water of the extract component containing cauliflower and preparation method thereof |
CN109303746A (en) * | 2018-12-13 | 2019-02-05 | 广州环亚化妆品科技有限公司 | A kind of prebiotic compositions and its preparation method and application |
CN110536675A (en) * | 2017-06-21 | 2019-12-03 | 可隆工业株式会社 | For skin moisture-keeping and increase elastic environmentally protective cosmetic combination |
CN110652480A (en) * | 2019-10-24 | 2020-01-07 | 樊瑞 | Skin care composition for repairing skin and preparation method thereof |
CN110664672A (en) * | 2018-07-02 | 2020-01-10 | 中山市泛华精细化学品有限公司 | Nourishing, moisturizing and repairing cosmetic |
CN111388398A (en) * | 2020-04-13 | 2020-07-10 | 佛山秘码中医馆有限公司 | Chinese herbal medicine liquid for increasing skin barrier function |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6387382B1 (en) * | 1998-11-23 | 2002-05-14 | Axiom Laboratories, Inc. | Water-proof, respirable, skin barrier composition |
CN104254313A (en) * | 2012-03-19 | 2014-12-31 | 科蒂德国有限责任公司 | Cosmetic skin composition with soothing effect and its use |
CN104323945A (en) * | 2014-10-20 | 2015-02-04 | 郁丁丁 | Soft lotion and preparation method thereof |
CN104434768A (en) * | 2014-12-10 | 2015-03-25 | 上海新高姿化妆品有限公司 | Moisturizing lotion with slow-release efficacy and preparation method of moisturizing lotion |
-
2015
- 2015-12-30 CN CN201511029242.4A patent/CN105380870A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6387382B1 (en) * | 1998-11-23 | 2002-05-14 | Axiom Laboratories, Inc. | Water-proof, respirable, skin barrier composition |
CN104254313A (en) * | 2012-03-19 | 2014-12-31 | 科蒂德国有限责任公司 | Cosmetic skin composition with soothing effect and its use |
CN104323945A (en) * | 2014-10-20 | 2015-02-04 | 郁丁丁 | Soft lotion and preparation method thereof |
CN104434768A (en) * | 2014-12-10 | 2015-03-25 | 上海新高姿化妆品有限公司 | Moisturizing lotion with slow-release efficacy and preparation method of moisturizing lotion |
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106074353A (en) * | 2016-06-28 | 2016-11-09 | 广东轻工职业技术学院 | A kind of solid cosmetic water and production technology thereof |
CN106074353B (en) * | 2016-06-28 | 2019-06-14 | 广东轻工职业技术学院 | A kind of toner and its production technology |
CN106333889A (en) * | 2016-08-24 | 2017-01-18 | 登封市科创商务咨询有限公司 | Natural organic firming lotion |
CN106511171A (en) * | 2016-12-06 | 2017-03-22 | 广州聚禅现代农业研究院有限公司 | Amaranth polysaccharide-containing beautifying lotion |
CN107669532A (en) * | 2016-12-12 | 2018-02-09 | 青岛大学 | Suncream |
CN106606450A (en) * | 2016-12-23 | 2017-05-03 | 惠州市七分妆化妆品有限公司 | Plant nutrient water |
CN106726654A (en) * | 2017-04-06 | 2017-05-31 | 湖南御家化妆品制造有限公司 | A kind of xylitol moisture-keeping composition and its application in cosmetics |
CN107007511A (en) * | 2017-05-23 | 2017-08-04 | 广州珈源日化用品有限公司 | Cosmetic composition with hormone-healing face effect and preparation method and application thereof |
CN110536675A (en) * | 2017-06-21 | 2019-12-03 | 可隆工业株式会社 | For skin moisture-keeping and increase elastic environmentally protective cosmetic combination |
CN107362078A (en) * | 2017-06-28 | 2017-11-21 | 权启康 | A kind of Chinese herbal medicine toner |
CN107375106A (en) * | 2017-08-25 | 2017-11-24 | 漳浦彩露华化妆品有限公司 | A kind of moist water and preparation method thereof |
CN107998022A (en) * | 2017-12-19 | 2018-05-08 | 武汉北度生物科技有限公司 | A kind of antioxidation cosmetic water of the extract component containing cauliflower and preparation method thereof |
CN110664672A (en) * | 2018-07-02 | 2020-01-10 | 中山市泛华精细化学品有限公司 | Nourishing, moisturizing and repairing cosmetic |
CN109303746A (en) * | 2018-12-13 | 2019-02-05 | 广州环亚化妆品科技有限公司 | A kind of prebiotic compositions and its preparation method and application |
CN109303746B (en) * | 2018-12-13 | 2021-05-28 | 广州环亚化妆品科技有限公司 | Prebiotic composition and preparation method and application thereof |
CN110652480A (en) * | 2019-10-24 | 2020-01-07 | 樊瑞 | Skin care composition for repairing skin and preparation method thereof |
CN111388398A (en) * | 2020-04-13 | 2020-07-10 | 佛山秘码中医馆有限公司 | Chinese herbal medicine liquid for increasing skin barrier function |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105380870A (en) | Toning lotion with efficacy of repairing cuticle and a preparation method of toning lotion | |
CN108158869B (en) | Antibacterial wet tissue liquid, wet tissue and preparation method of wet tissue | |
CN105411960A (en) | Mask with acne inhibition effect and preparation method thereof | |
CN111388358A (en) | Plant essential oil composition with mite-killing and acne-removing effects, and preparation and application thereof | |
CN107184499A (en) | A kind of long-acting moisturizing emulsion mask composition of natural botanical source and preparation method thereof | |
CN111616992B (en) | Skin barrier repair compound, skin base fluid and preparation method thereof | |
CN101744757A (en) | Preservative-free moisturizing firming cosmetic containing natural and organic ingredients | |
CN113786362B (en) | Toning lotion composition with effects of relieving balance and protecting skin and preparation method thereof | |
KR101209189B1 (en) | herbal soap with antibacteria function | |
CN112402347A (en) | Acne-removing repair composition containing fibronectin and preparation method thereof | |
CN106619380A (en) | Anti-acne essence | |
CN110638742A (en) | Blackhead guiding composition, convergence relieving composition and blackhead removing composition consisting of blackhead guiding composition and convergence relieving composition | |
KR20130113729A (en) | The functional beauti-pacl and its manufacturing method | |
CN107137293A (en) | A kind of oil-control biological cleanser and preparation method thereof | |
CN108815072A (en) | A kind of plant composition fermentation magma and its preparation method and application | |
CN110840768B (en) | Artemisia argyi essence stock solution and preparation method thereof | |
CN113499294A (en) | Plant composition for cats with skin and hair care effect and application thereof | |
CN111759885A (en) | Sophora flavescens composition, sophora flavescens gel and preparation method thereof | |
CN105362129A (en) | Facial mask liquid containing folium artemisiae argyi extracting solution and preparation method of facial mask liquid | |
CN108186426B (en) | Antibacterial mask liquid, mask and preparation method of mask liquid | |
CN104398461A (en) | Anti-dry soft and moist cream and preparation method thereof | |
CN106377463A (en) | Hydrating toner composition free from preservatives | |
CN113679640A (en) | Natural nourishing skin-cleaning skin-care acne-removing facial cleansing gel and preparation method thereof | |
CN107822962A (en) | The Anti-bacterium hand cream that a kind of baby is applicable | |
KR20150122983A (en) | Comsmetic composition comprising mint vinegar |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160309 |