CN105362129A - Facial mask liquid containing folium artemisiae argyi extracting solution and preparation method of facial mask liquid - Google Patents
Facial mask liquid containing folium artemisiae argyi extracting solution and preparation method of facial mask liquid Download PDFInfo
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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Abstract
The invention belongs to the technical field of cosmetics, and in particularly relates to facial mask liquid containing folium artemisiae argyi extracting solution and a preparation method of the facial mask liquid. The facial mask liquid containing the folium artemisiae argyi extracting solution is mainly composed of the folium artemisiae argyi extracting solution, moutan bark extracting solution, witch hazel extracting solution, compound amino acid, carboxymethyl chitosan, hydroxyethyl cellulose, allantoin, propylene glycol, pentanediol, glycerol, a preservative and water. The facial mask liquid containing the folium artemisiae argyi extracting solution has broad-spectrum bactericidal activity and antianaphylaxis, has the efficacies of diminishing inflammation, relieving skin fatigue, resisting oxidation, promoting cell growth and accelerating wound healing, and also has the effects of replenishing water and preserving moisture. The facial mask liquid containing the folium artemisiae argyi extracting solution is free of irritation to the skin, causes no skin poisoning phenomenon after long-term use, is healthy and multi-purpose, and is suitable for use by various people.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid and preparation method thereof.
Background technology
Along with the development of society and the progress of science and technology, work and the life stress of people are increasing, and problem of environmental pollution is also more and more serious.Live in fast pace for a long time, diet is irregular and pollute in larger environment, causes the skin tolerance of people constantly to weaken, skin sensitivity, impaired situation are more and more serious, and the skin of more and more people presents sub-health state.Therefore, skin nursing becomes an indispensable part in people's life gradually.
Facial film is as one of cosmetics, and it has, and to improve skin effects remarkable, advantage easy to use and being well received by consumers.Facial film is that the non-woven fabrics mask being soaked with facial mask liquid is covered face 15-20 minute when using, temporarily face and extraneous air can be isolated with polluting like this, improve skin temperature, skin expansion pore, promotes sweat gland secretion and metabolism, makes the oxygen content of skin increase, be conducive to the oil substances that skin gets rid of the metabolic product of epidermis cell and accumulation, facial mask liquid in pad pasting infiltrates the horny layer of skin epidermis, makes skin become softness, naturally light, and flexible.
But; effect of moisturizing, whitening, speckle dispelling mainly paid attention to by current facial film on the market; but these facial films often can add a large amount of thickening agents; as materials such as card ripple, triethanolamine, sodium acrylate/sodium acryloyldimethyl taurate copolymers; and EDTA chelating agen and containing the antiseptic of Form aldehyde release body; there is certain zest to skin, easily there is inflammation, irritated phenomenon in life-time service.
Plant extract extracts to obtain from the plant of pure natural, and its alkaloid contained, flavonoid, organic acid and saponin isoreactivity material have sterilization, antiinflammatory, antipruritic effect, and are free from side effects.Therefore, the facial mask liquid containing plant extract is more and more subject to liking to be beautiful the favor of personage.
Chinese patent application 201210451965.3 discloses a kind of antiinflammatory facial mask liquid, described facial mask liquid is made up of raw materials such as green tea powder, glycerol, cucumber extract, fresh milk and Folium Menthae extract, the facial mask liquid prepared can effectively be alleviated scytitis, to no skin irritation, be applicable to sensitivity skin.But this facial mask liquid function singleness, does not meet the requirement of modern.
Chinese patent application 201510095165.6 discloses a kind of facial mask liquid promoting skin regeneration antiallergic, described facial mask liquid is made up of hyaluronic acid, Trenaxmine, hesperidin methyl, Sensor Chip CM 5, wheat protein hydrolyzed solution, Herba Lophatheri extracting solution, Radix Scutellariae extracting solution, red sage root extracting solution, ginger extract, Aloe extraction solution, Flos Chrysanthemi Indici extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution and 1,2-hexanediol.The facial mask liquid prepared from endogenous immunity moderation system antiinflammatory, and can activate the repair ability of skin self, uses rear skin comfort, can improve face's erythema, is applicable to all kinds of crowd and uses.But this facial mask liquid contains Trenaxmine, easily there is the phenomenon of dermal toxicity in life-time service, limits the application of this facial mask liquid greatly.
Summary of the invention
In order to solve, there is function singleness in facial mask liquid in prior art, safety is lower, the defect that antiinflammatory, antiallergic effect are poor, one is the object of the present invention is to provide to have antiallergic of releiving, prevent antibacterial invasion, eliminate skin itching and scytitis effect, and facial mask liquid and preparation method thereof containing Folium Artemisiae Argyi extractive liquid that safety is higher, to address the aforementioned drawbacks.
The invention provides a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid, comprise following component and parts by weight thereof:
Folium Artemisiae Argyi extractive liquid 8-16 part, Cortex Moutan extracting solution 5-10 part, Radix Hamamelidis Mollis extracting solution 4-8 part, aminoacids complex 2-6 part, carboxymethyl chitosan 0.1-0.5 part, hydroxyethyl-cellulose 0.2-0.6 part, allantoin 0.1-0.5 part, propylene glycol 1-5 part, pentanediol 1-3 part, glycerol 3-8 part, antiseptic 0.1-0.5 part and water 70-90 part.
Further, the described facial mask liquid containing Folium Artemisiae Argyi extractive liquid comprises following component and parts by weight thereof:
Folium Artemisiae Argyi extractive liquid 12 parts, Cortex Moutan extracting solution 8 parts, Radix Hamamelidis Mollis extracting solution 6 parts, aminoacids complex 4 parts, carboxymethyl chitosan 0.4 part, hydroxyethyl-cellulose 0.3 part, allantoin 0.3 part, propylene glycol 3 parts, pentanediol 2 parts, glycerol 6 parts, antiseptic 0.2 part and 80 parts, water.
Further, the preparation method of described Folium Artemisiae Argyi extractive liquid is: get dry Folium Artemisiae Argyi, pulverizes, adding Folium Artemisiae Argyi coarse powder weight 10-15 times of concentration is the ethanol of 60-80%, heating and refluxing extraction 2-3 time, filters, merging filtrate, by decompression filtrate recycling ethanol, obtains Folium Artemisiae Argyi extractive liquid.
Further, the preparation method of described Cortex Moutan extracting solution is: get Cortex Moutan and pulverize, add Cortex Moutan coarse powder weight 12-15 times of water, add the sodium chloride of medical material amount 5-10%, soak 5-10h, carry out vapor distillation, obtain Cortex Moutan extracting solution.
Further, the preparation method of described Radix Hamamelidis Mollis extracting solution is: get Radix Hamamelidis Mollis branch and leaf and pulverize, adding Radix Hamamelidis Mollis coarse powder weight 5-8 times of concentration is the ethanol of 60-80%, ultrasonic extraction 2-3 time, each 1-2h, filters, merging filtrate, by decompression filtrate recycling ethanol, obtains Radix Hamamelidis Mollis extracting solution.
Further, described antiseptic is one in phenoxyethanol and Sensiva SC50 or its compositions.
Folium Artemisiae Argyi extractive liquid in the facial mask liquid containing Folium Artemisiae Argyi extractive liquid provided by the invention contains abundant volatile oil, flavone, eudesmane and triterpene substance, it has effect of antiallergic, resisting fatigue, antioxidation and sterilization, and to no skin irritation, be a kind of pure natural, non-stimulated cosmetic composition.
Modern study finds, the elastoser of Cortex Moutan extracting solution to metalloproteases has inhibitory action, has activation to cathepsin, shows that Cortex Moutan extracting solution has skin-active and anti-ageing function, in conjunction with the antioxidant of Cortex Moutan extracting solution, to skin, there is obvious aging resistance effect.Containing multiple tanning matter and the multiple active component of releiving, restraining in Radix Hamamelidis Mollis extracting solution, there is antiinflammatory, antiallergic, mitigation irriate skin, the effect of convergence pore, moisturizing, moisturizing.
Aminoacids complex is the natural moistening factor in keratodermatitis, skin that is aging, sclerosis can be made to recover hydrability, can effectively prevent horny layer moisture loss, skin is moistened with flexible.Carboxymethyl chitosan is a kind of water-solubility chitosan derivative, has antibacterial, fresh-keeping effect, is conducive to the shelf-life extending product.Allantoin is a kind of nontoxic, tasteless, nonirritant, without hypersensitive white crystal, it has Promote cell's growth, accelerating wound, horny layer softening albumen, sterilization, pain relieving, antioxidative effect, makes skin exquisiteness, water tender, dynamic.
Facial mask liquid containing Folium Artemisiae Argyi extractive liquid provided by the invention has effect of the bactericidal properties of wide spectrum, antiallergic, antiinflammatory, Promote cell's growth and accelerating wound, also has the effect of moisturizing, moisturizing simultaneously.Making skin moisten after using fine and smooth, flexible, is a kind of facial mask liquid meeting modern and require.Soak non-woven fabrics mask during the application of the facial mask liquid containing Folium Artemisiae Argyi extractive liquid provided by the invention, every sheet leaching, containing facial mask liquid 30g, obtains facial film finished product.First be equipped with the clean face of warm water with clean product during use, launched inwardly to be lightly spread in face by film cloth, flicking, to fitting completely, applies 15 ~ 20 minutes, uses weekly 2 ~ 3 times.
In addition, present invention also offers a kind of preparation method of the facial mask liquid containing Folium Artemisiae Argyi extractive liquid, comprise the following steps:
S1 heats water to 50-80 DEG C, adds allantoin, is stirred to and dissolves completely, obtains allantoin liquid;
Glycerol, propylene glycol and pentanediol add in carboxymethyl chitosan and hydroxyethyl-cellulose and stir by S2, obtain mixed liquor;
The mixed liquor that allantoin liquid and step S2 that step S1 obtains by S3 obtain is mixed homogeneously, and then adds Folium Artemisiae Argyi extractive liquid, Cortex Moutan extracting solution, Radix Hamamelidis Mollis extracting solution, aminoacids complex and antiseptic, stirs, to obtain final product.
Compared with prior art, the facial mask liquid containing Folium Artemisiae Argyi extractive liquid provided by the invention has following advantage:
(1) facial mask liquid containing Folium Artemisiae Argyi extractive liquid provided by the invention has effect of the bactericidal properties of wide spectrum, antiallergic, antiinflammatory, Promote cell's growth and accelerating wound, and also have the effect of moisturizing, moisturizing, be a kind of facial mask liquid meeting modern and require simultaneously;
(2) facial mask liquid containing Folium Artemisiae Argyi extractive liquid provided by the invention is to no skin irritation, and life-time service there will not be the phenomenon of dermal toxicity, is a kind of health, multi-functional facial mask liquid, is conducive to large-scale production and the sale of this facial mask liquid.
Accompanying drawing explanation
Fig. 1 is to the vegetative map of HACAT cell containing the facial mask liquid of Folium Artemisiae Argyi extractive liquid;
Fig. 2 is the wound healing figure of HACAT cell;
Fig. 3 is to the wound healing figure of HACAT cell containing the facial mask liquid of Folium Artemisiae Argyi extractive liquid.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.Each component of the present invention is conventional commercial product, and such as: allantoin is purchased from Merck KGaA company, model is: RonaCareAllantion101015; Aminoacids complex is purchased from Lang De company of Korea S hundred, and model is AminoAcidComplex (B).
embodiment 1,the preparation of Folium Artemisiae Argyi extractive liquid
Get dry Folium Artemisiae Argyi, pulverize, adding Folium Artemisiae Argyi coarse powder weight 10 times of concentration is the ethanol of 70%, heating and refluxing extraction 2 times, and filter, merging filtrate, by decompression filtrate recycling ethanol, obtains Folium Artemisiae Argyi extractive liquid.
embodiment 2,the preparation of Cortex Moutan extracting solution
Get Cortex Moutan to pulverize, add Cortex Moutan coarse powder weight 12 times of water, add the sodium chloride of medical material amount 5%, soak 5h, carry out vapor distillation, obtain Cortex Moutan extracting solution.
embodiment 3,the preparation of Radix Hamamelidis Mollis extracting solution
Get Radix Hamamelidis Mollis branch and leaf to pulverize, adding Radix Hamamelidis Mollis coarse powder weight 5 times of concentration is the ethanol of 70%, ultrasonic extraction 2 times, each 1.5h, and filter, merging filtrate, by decompression filtrate recycling ethanol, obtains Radix Hamamelidis Mollis extracting solution.
embodiment 4,a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
The described facial mask liquid containing Folium Artemisiae Argyi extractive liquid comprises following component and parts by weight thereof:
Folium Artemisiae Argyi extractive liquid 8 parts, Cortex Moutan extracting solution 5 parts, Radix Hamamelidis Mollis extracting solution 4 parts, aminoacids complex 2 parts, carboxymethyl chitosan 0.1 part, hydroxyethyl-cellulose 0.2 part, allantoin 0.1 part, propylene glycol 2 parts, pentanediol 1 part, glycerol 4 parts, phenoxyethanol 0.1 part and 70 parts, water.
Preparation method:
S1 heats water to 50 DEG C, adds allantoin, is stirred to and dissolves completely, obtains allantoin liquid;
Glycerol, propylene glycol and pentanediol add in carboxymethyl chitosan and hydroxyethyl-cellulose and stir by S2, obtain mixed liquor;
The mixed liquor that allantoin liquid and step S2 that step S1 obtains by S3 obtain is mixed homogeneously, and then adds Folium Artemisiae Argyi extractive liquid, Cortex Moutan extracting solution, Radix Hamamelidis Mollis extracting solution, aminoacids complex and antiseptic, stirs, to obtain final product.
embodiment 5,a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
The described facial mask liquid containing Folium Artemisiae Argyi extractive liquid comprises following component and parts by weight thereof:
Folium Artemisiae Argyi extractive liquid 12 parts, Cortex Moutan extracting solution 8 parts, Radix Hamamelidis Mollis extracting solution 6 parts, aminoacids complex 4 parts, carboxymethyl chitosan 0.4 part, hydroxyethyl-cellulose 0.3 part, allantoin 0.3 part, propylene glycol 3 parts, pentanediol 2 parts, glycerol 6 parts, Sensiva SC50 0.2 part and 80 parts, water.
Preparation method is similar to Example 4.
embodiment 6,a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
The described facial mask liquid containing Folium Artemisiae Argyi extractive liquid comprises following component and parts by weight thereof:
Folium Artemisiae Argyi extractive liquid 16 parts, Cortex Moutan extracting solution 10 parts, Radix Hamamelidis Mollis extracting solution 8 parts, aminoacids complex 6 parts, carboxymethyl chitosan 0.5 part, hydroxyethyl-cellulose 0.6 part, allantoin 0.5 part, propylene glycol 5 parts, pentanediol 3 parts, glycerol 8 parts, phenoxyethanol 0.3 part and 90 parts, water.
Preparation method is similar to Example 4.
comparative example 1,a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
The described facial mask liquid containing Folium Artemisiae Argyi extractive liquid comprises following component and parts by weight thereof:
Folium Artemisiae Argyi extractive liquid 12 parts, Radix Hamamelidis Mollis extracting solution 6 parts, aminoacids complex 4 parts, carboxymethyl chitosan 0.4 part, hydroxyethyl-cellulose 0.3 part, allantoin 0.3 part, propylene glycol 3 parts, pentanediol 2 parts, glycerol 6 parts, phenoxyethanol 0.2 part and 80 parts, water.
Preparation method is similar to Example 4.
comparative example 2,a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
The described facial mask liquid containing Folium Artemisiae Argyi extractive liquid comprises as component and parts by weight thereof:
Folium Artemisiae Argyi extractive liquid 12 parts, Cortex Moutan extracting solution 8 parts, Radix Hamamelidis Mollis extracting solution 6 parts, aminoacids complex 4 parts, carboxymethyl chitosan 0.4 part, hydroxyethyl-cellulose 0.3 part, propylene glycol 3 parts, pentanediol 2 parts, glycerol 6 parts, Sensiva SC50 0.2 part and 80 parts, water.
Preparation method is similar to Example 4.
test example one,containing the bacteriostatic test of the facial mask liquid of Folium Artemisiae Argyi extractive liquid
1, test material: the facial mask liquid containing Folium Artemisiae Argyi extractive liquid of embodiment 4, embodiment 5, embodiment 6 and comparative example 1 preparation.
2, for the preparation of examination bacterium
Respectively escherichia coli, staphylococcus aureus, Bacillus thuringiensis, bacillus subtilis are seeded in Carnis Bovis seu Bubali cream culture fluid in aseptic processing room, aspergillosis, beer yeast and candida mycoderma are seeded in bean sprout juice culture fluid, under 28-30 DEG C of condition, cultivate 1-3d.
3, test method:
Adopt agar punching diffusion method, sterile petri dish is divided into 5 groups, often organize 4, Carnis Bovis seu Bubali cream culture fluid after sterilizing is poured in sterile petri dish, every ware 15 ~ 20mL, after it solidifies, draw 0.1mL escherichia coli, staphylococcus aureus, Bacillus thuringiensis and bacillus subtilis with Sterile pipette is added on culture dish for examination bacterium, and coating evenly, is often organized each culture dish and added different strains.
Sterile petri dish is divided into 5 groups, often organize 3, bean sprout juice culture fluid after sterilizing is poured in sterile petri dish, every ware 15 ~ 20mL, after it solidifies, draw 0.1mL aspergillosis, beer yeast and candida mycoderma with Sterile pipette is added on culture dish for examination bacterium, coating evenly, is often organized each culture dish and is added different strains.
After coating, then in culture medium, make a call to 5 equidistant holes with the sterilizing stainless steel card punch of external diameter 4mm.With the facial mask liquid 30 μ L containing Folium Artemisiae Argyi extractive liquid of micro sample adding appliance difference extraction embodiment 4, embodiment 5, embodiment 6 and comparative example 1 preparation, a middle hole is added equivalent sterilized water and is done matched group, carries out labelling.Cultivate 24h at antibacterial being placed in 37 DEG C, at Molds and yeasts being placed in 28 DEG C, cultivate 72h.Measure antibacterial circle diameter (bacteriostatic diameter mm counts), test repetition 5 times, with 5 meansigma methodss for antibacterial circle diameter.
4, result of the test
Result of the test is as shown in table 1.
Table 1 is containing the bacteriostatic test data of the facial mask liquid of Folium Artemisiae Argyi extractive liquid
As shown in Table 1, facial mask liquid containing Folium Artemisiae Argyi extractive liquid prepared by the present invention has significant inhibitory action to escherichia coli, staphylococcus aureus, Bacillus thuringiensis and bacillus subtilis, to aspergillosis, beer yeast and candida mycoderma, there is good inhibitory action, and comparative example 1 has lacked Cortex Moutan extracting solution, it is poor to the fungistatic effect of Bacillus thuringiensis, bacillus subtilis, aspergillosis, beer yeast and candida mycoderma, illustrates that Folium Artemisiae Argyi extractive liquid, Cortex Moutan extracting solution and Radix Hamamelidis Mollis extracting solution are used in combination and can work in coordination with enhancing bacteriostasis.
test example two,skin repair containing the facial mask liquid of Folium Artemisiae Argyi extractive liquid is tested
1, test material: the facial mask liquid containing Folium Artemisiae Argyi extractive liquid prepared by embodiment 5, HACAT cell, is purchased from Bo Gu bio tech ltd, Shanghai, and article No. is BG183.
2, test method:
To take the logarithm the HACAT cell of trophophase, be inoculated in 96 well culture plates, every hole 100uL.Be placed in 37 DEG C, 5%CO
2overnight incubation under condition.Be 3.125,6.25,12.5,25,50 and 100mg/mL with the concentration dilution of facial mask liquid containing Folium Artemisiae Argyi extractive liquid that embodiment 5 is prepared by DMEM culture medium.Next day takes out cell plates, abandons supernatant, and every hole adds the facial mask liquid of variable concentrations respectively, every hole 100uL, and each concentration all does 6 multiple holes.Not add the HACAT cell of facial mask liquid for normal cell group, at 37 DEG C, 5%CO
224h is cultivated under condition.Then in every hole, add the MTT solution 10uL that concentration is 5mg/mL successively, continue to hatch 4h.Discard culture supernatant 100uL in hole, then add 100uLDMSO in every hole and fully shake to crystal and fully dissolve.Enzyme-linked immunosorbent assay instrument is selected 570nm wavelength, measures each hole absorbance value (OD value).
3, result of the test:
Result of the test as shown in Figure 1.Facial mask liquid containing Folium Artemisiae Argyi extractive liquid prepared by the present invention can promote the propagation of HACAT cell, along with the increase of facial mask liquid concentration, the rate of increase of HACAT cell is in the rear downward trend that first rises, when facial mask liquid concentration is 6.25mg/mL, the rate of increase of HACAT cell reaches peak value, and the rate of increase of HACAT cell is on a declining curve subsequently.
test example three,wound healing containing the facial mask liquid of Folium Artemisiae Argyi extractive liquid is tested
1, test material: embodiment 5 prepares the facial mask liquid containing Folium Artemisiae Argyi extractive liquid, and HACAT cell, is purchased from Bo Gu bio tech ltd, Shanghai, and article No. is BG183.
2, test method:
To take the logarithm the HACAT cell of trophophase, be inoculated in 6 well culture plates, treat that HACAT cell 100% merges, at the equidistant horizontal line of 6 orifice plate back side stroke.Use 100uL rifle head at the longitudinal cut of cell monolayer, cause cultured cell wound model.Random packet after cut, is respectively matched group and test group, the cell maintenance medium process of matched group equivalent, and the facial mask liquid process containing Folium Artemisiae Argyi extractive liquid prepared by the embodiment 5 that test group working concentration is 6.25mg/mL.Process the situation of change near rear observation cut and drawn horizontal line joint, and 0,6,12,24h takes pictures respectively, measures the width of cut under fluorescence microscope.
3, result of the test
As shown in Figures 2 and 3, wherein A is matched group to result of the test, and B is test group.Containing the facial mask liquid of Folium Artemisiae Argyi extractive liquid, that adds prepared by the present invention effectively can promote that HACAT cell migration merges, illustrate that prepared by the present invention facial mask liquid containing Folium Artemisiae Argyi extractive liquid can promote the healing rate of wound.
test example four,containing the evaluation test of the facial mask liquid of Folium Artemisiae Argyi extractive liquid
1, test material: the facial film made containing the facial mask liquid of Folium Artemisiae Argyi extractive liquid of embodiment 4, embodiment 5, embodiment 6, comparative example 1 and comparative example 2 preparation.
2, tested crowd: choose 50 routine female volunteers, the age between 20 ~ 40 years old, volunteer choice criteria: there are the female volunteers of small pox or erythema in sensitivity skin, face.
3, test method:
Volunteer is divided into 5 groups at random, is respectively embodiment 4 groups, embodiment 5 groups, embodiment 6 groups, comparative example 1 group and comparative example 2 groups, often organizes 10 people.After each group of volunteer cleans face, get corresponding facial film, launched inwardly by facial film to be lightly spread in face, flicking, to fitting completely, applies 15 minutes, uses 2 times weekly.
Evaluate the moisturizing effect of the facial mask liquid containing Folium Artemisiae Argyi extractive liquid, antipruritic, zest, anti-inflammatory effects and whole structure after using 4 weeks, evaluation methodology is:
(1) moisturizing effect: A effect is fine, and B is effective, C effect is general, and D does not have effect;
(2) antipruritic: A effect is fine, and B is effective, C effect is general, and D does not have effect;
(3) zest: A is non-stimulated, B has point stimulation, but do not have red, itch, C has stimulation, have red, itch, D stimulates, red, swollen;
(4) anti-inflammatory effects: A effect is fine, and small pox or swelling and ache of erythema are disappeared, and B is effective, and small pox or erythema are not keenly felt, C effect is general, and small pox or swelling and ache of erythema also exist, and D does not have effect, and small pox or erythema swell and ache seriously;
(5) whole structure: A effect is fine, and B is effective, C effect is general, and D does not have effect.
4, result of the test:
Result of the test is as shown in table 2.
Table 2 is containing (4 weeks) on probation feedback conclusive table of the facial mask liquid of Folium Artemisiae Argyi extractive liquid
| Embodiment 4 groups | Embodiment 5 groups | Embodiment 6 groups | Comparative example 1 group | Comparative example 2 groups | |
| Moisturizing effect | B | A | B | A | C |
| Antipruritic | A | A | A | C | A |
| Zest | A | A | A | B | B |
| Anti-inflammatory effects | A | A | A | C | A |
| Whole structure | A | A | A | C | B |
As shown in Table 2, the facial mask liquid containing Folium Artemisiae Argyi extractive liquid prepared by the present invention has significant effect in moisturizing, antipruritic, antiinflammatory etc., and overall assessment effect is fine, is a kind of facial mask liquid meeting modern and require.
Claims (7)
1., containing a facial mask liquid for Folium Artemisiae Argyi extractive liquid, it is characterized in that, comprise following component and parts by weight thereof:
Folium Artemisiae Argyi extractive liquid 8-16 part, Cortex Moutan extracting solution 5-10 part, Radix Hamamelidis Mollis extracting solution 4-8 part, aminoacids complex 2-6 part, carboxymethyl chitosan 0.1-0.5 part, hydroxyethyl-cellulose 0.2-0.6 part, allantoin 0.1-0.5 part, propylene glycol 1-5 part, pentanediol 1-3 part, glycerol 3-8 part, antiseptic 0.1-0.5 part and water 70-90 part.
2. the facial mask liquid containing Folium Artemisiae Argyi extractive liquid as claimed in claim 1, is characterized in that, comprise following component and parts by weight thereof:
Folium Artemisiae Argyi extractive liquid 12 parts, Cortex Moutan extracting solution 8 parts, Radix Hamamelidis Mollis extracting solution 6 parts, aminoacids complex 4 parts, carboxymethyl chitosan 0.4 part, hydroxyethyl-cellulose 0.3 part, allantoin 0.3 part, propylene glycol 3 parts, pentanediol 2 parts, glycerol 6 parts, antiseptic 0.2 part and 80 parts, water.
3. the facial mask liquid containing Folium Artemisiae Argyi extractive liquid as claimed in claim 1 or 2, it is characterized in that, the preparation method of described Folium Artemisiae Argyi extractive liquid is:
Get dry Folium Artemisiae Argyi, pulverize, adding Folium Artemisiae Argyi coarse powder weight 10-15 times of concentration is the ethanol of 60-80%, heating and refluxing extraction 2-3 time, and filter, merging filtrate, by decompression filtrate recycling ethanol, obtains Folium Artemisiae Argyi extractive liquid.
4. the facial mask liquid containing Folium Artemisiae Argyi extractive liquid as claimed in claim 1 or 2, it is characterized in that, the preparation method of described Cortex Moutan extracting solution is:
Get Cortex Moutan to pulverize, add Cortex Moutan coarse powder weight 12-15 times of water, add the sodium chloride of medical material amount 5-10%, soak 5-10h, carry out vapor distillation, obtain Cortex Moutan extracting solution.
5. the facial mask liquid containing Folium Artemisiae Argyi extractive liquid as claimed in claim 1 or 2, it is characterized in that, the preparation method of described Radix Hamamelidis Mollis extracting solution is:
Get Radix Hamamelidis Mollis branch and leaf to pulverize, adding Radix Hamamelidis Mollis coarse powder weight 5-8 times of concentration is the ethanol of 60-80%, ultrasonic extraction 2-3 time, each 1-2h, and filter, merging filtrate, by decompression filtrate recycling ethanol, obtains Radix Hamamelidis Mollis extracting solution.
6. the facial mask liquid containing Folium Artemisiae Argyi extractive liquid as claimed in claim 1 or 2, is characterized in that, described antiseptic is one in phenoxyethanol and Sensiva SC50 or its compositions.
7. a preparation method for the facial mask liquid containing Folium Artemisiae Argyi extractive liquid as described in as arbitrary in claim 1-6, is characterized in that, comprise the following steps:
S1 heats water to 50-80 DEG C, adds allantoin, is stirred to and dissolves completely, obtains allantoin liquid;
Glycerol, propylene glycol and pentanediol add in carboxymethyl chitosan and hydroxyethyl-cellulose and stir by S2, obtain mixed liquor;
The mixed liquor that allantoin liquid and step S2 that step S1 obtains by S3 obtain is mixed homogeneously, and then adds Folium Artemisiae Argyi extractive liquid, Cortex Moutan extracting solution, Radix Hamamelidis Mollis extracting solution, aminoacids complex and antiseptic, stirs, to obtain final product.
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| CN110859864A (en) * | 2019-12-05 | 2020-03-06 | 江苏食品药品职业技术学院 | Preparation process of folium artemisiae argyi extract and application of folium artemisiae argyi extract in preparation of acute kidney injury medicine |
| CN113398622A (en) * | 2021-05-14 | 2021-09-17 | 暨南大学 | Supercritical CO2Method for preparing wormwood raw pulp by extraction and molecular distillation processes |
| CN114903821A (en) * | 2021-07-08 | 2022-08-16 | 包计贤 | A facial mask rich in natural medicine and its preparation method |
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