CN108371642A - A kind of spring equilibrium water and preparation method thereof - Google Patents

A kind of spring equilibrium water and preparation method thereof Download PDF

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CN108371642A
CN108371642A CN201810199889.9A CN201810199889A CN108371642A CN 108371642 A CN108371642 A CN 108371642A CN 201810199889 A CN201810199889 A CN 201810199889A CN 108371642 A CN108371642 A CN 108371642A
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parts
water
extract
equilibrium water
spring equilibrium
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CN108371642B (en
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王飞
王一飞
马婧
任哲
利奕成
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Guangdong Sunny Biomedical Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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Abstract

The invention belongs to technical field of skin care, and in particular to a kind of spring equilibrium water and preparation method thereof.The spring equilibrium water of the present invention is mainly made of felwort extracting solution, cherry extract, mulberries extract, wormwood hydrosol, Purslane extract, butanediol, pentanediol and deionized water.Spring equilibrium water provided by the invention has the function of the biocidal property of wide spectrum, antianaphylaxis, replenishing water and preserving moisture, cuticula reparation, while also having the effect of slowing down skin aging, promoting skin blood cycle and refresh the mind.And the spring equilibrium water is conducive to safeguard skin stabilization health in spring use, various people is suitble to use to no skin irritation.

Description

A kind of spring equilibrium water and preparation method thereof
Technical field
The invention belongs to technical field of skin care, and in particular to a kind of spring equilibrium water and preparation method thereof.
Technical background
《The Yellow Emperor's Canon of Internal Medicine》In mention spring, all things on earth recovery, people should go to bed early and get up early.Spring human body is gradually Table, skin stretching, human recycle system's function are reinforced, and the supply of skin peripheral blood increases, and sweat gland secretion increases, each organ burden It aggravates, Central nervous system generates a kind of effect of calm hypnosis, and drowsiness to make one tired lazyness, here it is " the spring of civil theory It is tired ".But sleep is unfavorable for YANG QI tending to rise in nature, therefore we will like the Nature, make the feelings will of oneself and spring all things on earth hair tonic it Gas phase is harmonious, and the irritability of such human body will reconcile smoothly, makes whole body qi and blood and smooth, the five internal organs peace.
Spring, people just experienced the season of winter Tibetan.After the maintenance by winter, melanin is reduced skin, Cuticula is thinning, poor to the protective capacities of ultraviolet light, just as the flower in greenhouse.Spring belongs to " wood " on the five-element, this Ji Duofeng, all things on earth are recovered, and the dust in air easily induces skin allergy.
Nowadays social economy is constantly progressive, and people's living standard also accordingly improves, cosmetics have become people Live in necessary article improve our skin.However as the development of chemical industry, in order to improve user in short-term Between usage experience and it is cost-effective increase economic efficiency, mostly unavoidably addition is much unfavorable for skin care to skin care item Ingredient, such as essence, preservative and hormone.Hormone face, skin care item cosmetic allergic contact dermatitis event happen occasionally.Much like to be beautiful in life Personage can select some folk prescription skin cares such as safer fruits and vegetables and Chinese herbal medicine in order to avoid this present situation.However without a large amount of Scientific research, the combination of one or several single water fruits and vegetables or Chinese herbal medicine, un-extracted active ingredient and scientific matching, skin care effect Fruit may run counter to desire.
Comply with the market demand, natural plant kind product due to the use of safety, action temperature and the advantages that and welcome.
Chinese patent application 201310729425.1 discloses a kind of toner and preparation method thereof containing herbal ingredients, The toner includes polyalcohol moisturizer, sodium chloride, emollient, Sodium Hyaluronate, stabilizer, preservative, pretreated The raw materials such as plant petals, deionized water form, the invention prepare technique simplify, effectively by plant petals natural scents and Nutriment gradually in sustained release to toner, makes toner contain the natural flavor in valve and all nutritional ingredients, prepares foster Divide content height, maintaining skin effect good and the nutrition toner of highly effective and safe without synthetic perfume and surfactant.
Chinese patent application 201210597528.2 discloses a kind of rose and lotus leaf toner and preparation method thereof, institute It includes the raw materials such as rose liquid distilled from honeysuckle flowers or lotus leaves, lotus leaf drink, glycerine, hyaluronic acid, VC, VE composition to state toner, not only has moisturizing, dispels The effect of acne, is suitble to various skin quality, moreover it is possible to which consolidation, skin of releiving enable that skin is careful, smooth, microgroove is reduced.
All it is different in the state of 1 year Various Seasonal, skin.However skin care item on the market are directed to not yet Various Seasonal develops a kind of surfactant of suitable masses, and in spring, people can easily be stranded, and is in the season occurred frequently of skin allergy Section, can also face the trying situation of cuticula weakness, therefore be directed to the characteristic in this season in spring, when working out one kind and complying with day Change pure natural, without side-effects and with moisturizing, anti-anaphylaxis, repair cuticula, the skin care item of stimulating effect are the weights of this field Want one of research topic.
Invention content
In order to solve surfactant in the prior art, there are anti-inflammatory, antiallergy, moisturizing and the poor defect of repair ability, this hairs It is bright to be designed to provide a kind of biocidal property with wide spectrum, antianaphylaxis, replenishing water and preserving moisture, cuticula reparation, simultaneously Also there is the spring equilibrium water and preparation method thereof slowed down skin aging, promote skin blood cycle and the effect that refreshes the mind, with Solve drawbacks described above.
The present invention provides a kind of spring equilibrium waters, including following component and its parts by weight:
10-20 parts of felwort extracting solution, 20-40 parts of cherry extract, 20-40 parts of mulberries extract, wormwood hydrosol 10-20 Part, 20-40 parts of Purslane extract, 5-12 parts of butanediol, 0.3-0.5 parts of pentanediol and 30-50 parts of deionized water.
Further, the spring equilibrium water includes following component and its parts by weight:
15 parts of felwort extracting solution, 30 parts of cherry extract, 30 parts of mulberries extract, 15 parts of wormwood hydrosol, purslane carry Take 40 parts of 30 parts of liquid, 8 parts of butanediol, 0.4 part of pentanediol and deionized water.
Further, the felwort extraction liquid and preparation method thereof is:
Weigh dry felwort root, crush to obtain 200 mesh micro mists, by after crushing felwort micro mist and volume fraction be The ethyl alcohol of 70-75% is added in reaction kettle, and the mass ratio of wherein ethyl alcohol and felwort micro mist is 8: 1-10: 1, said mixture After reacting 2-5h under the conditions of 71-79 DEG C in reaction kettle, by products therefrom by decolourizing in decolorizing column, then with 0.2 μ M organic system miillpore filters be filtered by vacuum, finally distill out ethyl alcohol to get.
Further, the preparation method of the cherry extract is:
Fresh stoning cherry is weighed, is squeezed the juice, gained cherry juice is micro- with 0.2 μm of water system by the product in decolorizing column, obtained Hole filter membrane vacuum filtration to get.
Further, the preparation method of the mulberries extract is:
Fresh mulberries are weighed, are squeezed the juice, for gained mulberry juice by decolorizing column, it is that 2-5% gelatin is molten that volume fraction, which is then added, Liquid adds ethyl alcohol to acid content up to 70%~80%, and the wherein mass ratio of mulberry juice and gelatin solution is 3: 1-6: 1, mulberries The mass ratio of juice and ethyl alcohol is 1: 3-1: 5, and products therefrom stands 6h, is filtered by vacuum with 0.2 μm of water system miillpore filter, is finally distilled Go out ethyl alcohol to get.
Further, the wormwood hydrosol preparation method is:
It weighs fresh folium artemisiae argyi to be ground into folium artemisiae argyi slurries input distillation still with pulverizer, folium artemisiae argyi 5 times of weight of slurries is added Deionized water, adds 3-10 zeolites, accesses steam heated still, heats 2-3h, vapor tension control in 0.2-0.5MPa, Be heated to distillation temperature in the kettle be 60-70 DEG C when, open condenser be added cooling water, by above-mentioned mixed liquor import oil water separator In isolate distillate, resurgent returns in distillation still, collects water layer liquid, finally by gained water layer liquid by decolorizing column, i.e., .
Further, the preparation method of the Purslane extract is:
The part of stem leaf for weighing fresh purslane, squeezes the juice, and gained purslane extract is used by the product in decolorizing column, obtained 0.2 μm of water system miillpore filter vacuum filtration to get.
Further, the decolorizing column is Carb-GCB solid-phase extraction columns.
Further, the pH value of the spring equilibrium water is between 4.5-6.5.
Felwort extracting solution in spring equilibrium water provided by the invention has anti-oxidant, anti-inflammatory, antibacterial and moisturizing The effect of, and be a kind of pure natural, non-stimulated cosmetic composition to no skin irritation.Phosphatidyl in mulberries extract Inositol, phosphatidic acid belong to natural phospholipid, the ability that phosphatide has hygroscopicity and is easy in skin permeation, therefore can fetter in skin Moisture prevents from having dry skin, and repairs skin barrier, and then keep skin emolliency smooth and healthy.With the metabolism of reinforcement skin, town Determine sensitive, reinforce the resistivity of skin and repairs the effect of skin barrier.Cherry extract, have convergence analgesic and Whitening effect can be good at resistivity and whitening capability that calm sensitive reinforces skin.
Spring equilibrium water provided by the invention can form unique protective film in cell surface, can effectively remain thin Cytoactive has good protective effect to skin.Spring equilibrium water provided by the invention has the biocidal property of wide spectrum, antiallergy Property, replenishing water and preserving moisture, cuticula reparation effect, while also have slow down skin aging, promote skin blood cycle and refresh oneself awake The effect of brain.And the spring equilibrium water is conducive to safeguard skin stabilization health in spring use, be suitble to no skin irritation Various people use.
In addition, the present invention also provides a kind of preparation method of spring equilibrium water, include the following steps:
S1 heats water to 60-70 DEG C, and allantoin is added, and stirs to being completely dissolved, obtains allantoin liquid, is then added penta 2 Alcohol is uniformly mixed;
S2 stirs evenly felwort extracting solution, cherry mulberries mixed extract, Purslane extract, wormwood hydrosol, obtains Mixed liquor;
S3 mixed liquor that step S1 is obtained is uniformly mixed with the obtained mixed liquors of step S2 to get.
Compared with prior art, spring equilibrium water provided by the invention has the advantage that:
(1) there is antiallergy, moisturizing, cuticula reparation, anti-oxidant and awake skin to carry for spring equilibrium water provided by the invention The effect of god is that one kind meeting modern's requirement, the surfactant that especially suitable spring uses.
(2) main component of spring equilibrium water provided by the invention is water fruits and vegetables and Chinese medicine composite parts, natural materials The phenomenon that comparision contents are high, small to the irritation of skin, and long-time service is not in dermal toxicity is suitble to various people to use.
Description of the drawings:Fig. 1 is external application the present embodiment 4, embodiment 5, embodiment 6 spring equilibrium water to pruitus, skin The female volunteers keratoderma of allergy or slightly damaged repairs degree.
Specific implementation mode:
The following describes the present invention further through the description of specific embodiments, but this is not the limit to the present invention System, those skilled in the art's basic thought according to the present invention can make various modifications or improvements, but without departing from this The basic thought of invention, is all within the scope of the present invention.
Embodiment 1, felwort extraction liquid and preparation method thereof are:
Weigh dry felwort root, crush to obtain 200 mesh micro mists, by after crushing felwort micro mist and volume fraction be 70% ethyl alcohol is added in reaction kettle, and the mass ratio of wherein ethyl alcohol and felwort micro mist is 9: 1, and said mixture is in reaction kettle In under the conditions of 72 DEG C react 3h after, by products therefrom by decolourizing in Carb-GCB solid-phase extraction columns, then with 0.2 μm Organic system miillpore filter be filtered by vacuum, finally distill out ethyl alcohol to get.
Embodiment 2, the preparation method of cherry extract are:
Fresh stoning cherry is weighed, is squeezed the juice, gained cherry juice is obtained by decolourizing in Carb-GCB solid-phase extraction columns Product with 0.2 μm of water system miillpore filter vacuum filtration to get.
Embodiment 3, the preparation method of mulberries extract are:
Fresh mulberries are weighed, are squeezed the juice, gained mulberry juice in Carb-GCB solid-phase extraction columns by by decolourizing, then Addition volume fraction is 3% gelatin solution, adds ethyl alcohol to acid content up to 75%, the wherein quality of mulberry juice and gelatin solution Than being 5: 1, the mass ratio of mulberry juice and ethyl alcohol is 1: 4, and products therefrom stands 6h, is filtered by vacuum with 0.2 μm of water system miillpore filter, Finally distill out ethyl alcohol to get.
Embodiment 4, wormwood hydrosol preparation method are:
It weighs fresh folium artemisiae argyi to be ground into folium artemisiae argyi slurries input distillation still with pulverizer, folium artemisiae argyi 5 times of weight of slurries is added Deionized water adds 6 zeolites, accesses steam heated still, heats 3h, and vapor tension control is heated to steaming in 0.3MPa Evaporate temperature in the kettle be 65 DEG C when, open condenser be added cooling water, will above-mentioned mixed liquor import oil water separator in isolate steaming Distillate, resurgent return distillation still in, collect water layer liquid, finally by gained water layer liquid by Carb-GCB solid-phase extraction columns into Row decoloration to get.
Embodiment 5, the preparation method of Purslane extract are:
The part of stem leaf for weighing fresh purslane, squeezes the juice, gained purslane extract by Carb-GCB solid-phase extraction columns into Row decoloration, 0.2 μm of water system miillpore filter of obtained product be filtered by vacuum to get.
Embodiment 6, a kind of spring equilibrium water
The spring equilibrium water is made of following component and its parts by weight:
10 parts of felwort extracting solution, 20 parts of cherry extract, 20 parts of mulberries extract, 10 parts of wormwood hydrosol, purslane carry Take 30 parts of 20 parts of liquid, 5 parts of butanediol, 0.3 part of pentanediol and deionized water.
Preparation method:
The preparation method of night in the spring equilibrium water, includes the following steps:
S1 heats water to 65 DEG C, and allantoin is added, and stirs to being completely dissolved, obtains allantoin liquid, pentanediol is then added It is uniformly mixed;
S2 stirs evenly felwort extracting solution, cherry mulberries mixed extract, Purslane extract, wormwood hydrosol, obtains Mixed liquor;
S3 mixed liquor that step S1 is obtained is uniformly mixed with the obtained mixed liquors of step S2 to get.
Embodiment 7, a kind of spring equilibrium water
The spring equilibrium water is made of following component and its parts by weight:
15 parts of felwort extracting solution, 30 parts of cherry extract, 30 parts of mulberries extract, 15 parts of wormwood hydrosol, purslane carry Take 40 parts of 30 parts of liquid, 8 parts of butanediol, 0.4 part of pentanediol and deionized water.
Preparation method is similar to Example 6.
Embodiment 8, a kind of spring equilibrium water
The spring equilibrium water is made of following component and its parts by weight:
20 parts of felwort extracting solution, 40 parts of cherry extract, 40 parts of mulberries extract, 20 parts of wormwood hydrosol, purslane carry Take 50 parts of 40 parts of liquid, 12 parts of butanediol, 0.5 part of pentanediol and deionized water.
Preparation method is similar to Example 6.
Comparative example 1, a kind of spring equilibrium water
The spring equilibrium water is made of following component and its parts by weight:
15 parts of felwort extracting solution, 30 parts of cherry extract, 15 parts of wormwood hydrosol, 30 parts of Purslane extract, butanediol 8 40 parts of part, 0.4 part of pentanediol and deionized water.
Preparation method is similar to Example 6.
Comparative example 2, a kind of spring equilibrium water
The spring equilibrium water is made of following component and its parts by weight:
15 parts of felwort extracting solution, 30 parts of mulberries extract, 15 parts of wormwood hydrosol, 30 parts of Purslane extract, butanediol 8 40 parts of part, 0.4 part of pentanediol and deionized water.
Preparation method is similar to Example 6.
Test example one, spring equilibrium water bacteriostatic test:
1, test material:Embodiment 6, embodiment 7, embodiment 8, comparative example 1 and comparative example 2 prepare spring equilibrium water and Physiological saline, cherry extract, mulberries extract, the cherry mulberries mixed extract (body of cherry extract and mulberries extract Product is than being 1: 1).
2, for the preparation of examination bacterium
Respectively by Escherichia coli, staphylococcus aureus, bacillus subtilis and star nocar in sterile room Bacterium is seeded in beef extract culture solution, and aspergillus niger and Candida are seeded in bean sprout juice culture solution, in 28-30 DEG C of condition Lower culture 1-30 minutes.
3, test method:
Diffusion method is punched using agar, sterile petri dish is divided into 9 groups, every group 4, by the beef extract culture solution after sterilizing It pours into sterile petri dish, per 15~20mL of ware, 0.1mL Escherichia coli, golden yellow is drawn with Sterile pipette after its solidification Staphylococcus, bacillus subtilis and star nocardia are added on culture dish, and coating is uniform, and every group of each culture dish is added not Same strain.
Sterile petri dish is divided into 9 groups, every group 2, the bean sprout juice culture solution after sterilizing is poured into sterile petri dish, often 15~20mL of ware is added to culture dish with Sterile pipette absorption 0.1mL aspergillus nigers and Candida after its solidification for examination bacterium On, coating is uniform, and different strains is added in every group of each culture dish.
After coating, then the sterilizing stainless steel card punch of outer diameter 4mm is used to make a call to 9 equidistant holes on culture medium. It is balanced containing spring with prepared by micro sample adding appliance difference extraction embodiment 6, embodiment 7, embodiment 8, comparative example 1 and comparative example 2 Water liquid 30 μ L and 30 μ L of cherry extract, 30 μ L of mulberries extract, 30 μ L (cherry extracts 15 of cherry mulberries mixed extract 15 μ L of μ L and mulberries extract), intermediate hole addition normal saline does control group, marks.Bacterium is placed in 37 DEG C Lower culture for 24 hours, black-koji mould and Candida is placed at 28 DEG C and cultivate 72h.Antibacterial circle diameter (bacteriostatic diameter mm meters) is measured, Experiment is repeated 5 times, using 5 average values as antibacterial circle diameter.
4, test result
Test result is as shown in table 1.
The bacteriostatic test data of table 1 spring equilibrium water
As shown in Table 1, the spring equilibrium water that prepared by the present invention is to Escherichia coli, staphylococcus aureus, bacillus subtilis Bacterium, star nocardia have significant inhibiting effect, have good inhibiting effect to aspergillus niger and Candida.And it compares Example 1 has lacked mulberries extract, it is found that fungistatic effect is all lower than the effect of embodiment 6-8.Comparative example 2 has lacked cherry extraction Liquid, the effect that discovery obtains is also all good without embodiment 6-8, in conjunction with cherry extract and mulberries extract to Escherichia coli, gold Without apparent inhibiting effect, mulberries are mixed for staphylococcus aureus, bacillus subtilis, star nocardia, aspergillus niger, Candida Closing extracting solution has Escherichia coli, staphylococcus aureus, bacillus subtilis, star nocardia, aspergillus niger, Candida The inhibiting effect of a little, explainable cherry can interact with mulberries extract and can be cooperateed with spring equilibrium water other compositions Enhance the bacteriostasis of spring equilibrium water.
Test example two, spring equilibrium water usage experience evaluation test
1, test material:Spring equilibrium water prepared by embodiment 6, embodiment 7 and embodiment 8.
2, tested crowd:Choose female volunteers of 30 ages between -45 years old 20 years old, volunteer's standard:Skin scabies Itch, the women of spring easy allergy or slightly damaged, tests season:Spring.
3, test method:
Volunteer is randomly divided into 3 groups, every group of 10 people, respectively 6 groups of embodiment, 7 groups of embodiment, 8 groups of embodiment.Each group After the daily face cleaning of volunteer, facial-care is carried out with spring equilibrium water, it is 2-3 times daily, it is used continuously 28 days, and acquired at 28 days Data.
The antiallergy of spring equilibrium water, keratoderma reparation, antipruritic anti-inflammatory, moisturizing and entirety are imitated using after 28 days Fruit scores, and methods of marking is.
(1) antiallergic:No allergic phenomena score 3;Minimal irritation alleviates score 2 after a few minutes;Minimal irritation, skin The sense of discomfort long period could alleviate score 1.
(2) moisturizing:Effect score 3 very well;Effect generally score 2;There is no effect score 1.
(3) antipruritic:Effect score 3 very well;Effect generally score 2;There is no effect score 1.
(4) overall effect:Score 3, effect generally score 2 to effect very well;There is no effect score 1.
4, test result
Test result is as shown in table 2.
Table 2 spring equilibrium water is applicable in (28 days) feedback conclusive tables
Embodiment 6 Embodiment 7 Embodiment 8
Antiallergic 30 30 30
Moisturizing 29 30 30
It is antipruritic 30 30 30
Overall effect 30 30 30
As shown in Table 2, the spring equilibrium water that prepared by the present invention has obvious action in antiallergic, moisturizing, antipruritic etc., And overall assessment effect is fine, is a kind of surfactant meeting modern's requirement.
Test example three, spring equilibrium water keratoderma repairing test
1, test material:Spring equilibrium water prepared by embodiment 6, embodiment 7 and embodiment 8.
2, tested crowd:Choose female volunteers of 30 ages between -45 years old 20 years old, volunteer's standard:Skin scabies Itch, the women of skin allergy or slightly damaged, tests season:Spring.
3, test method:
Volunteer is randomly divided into 3 groups, every group of 10 people, respectively 4 groups of embodiment, 5 groups of embodiment, 6 groups of embodiment.Each group After the daily face cleaning of volunteer, facial-care is carried out with spring equilibrium water, it is 2-3 times daily, be used continuously 28 days, and the 7th day, 14 It, 21 days, 28 days gathered datas.Keratoderma repairs percentage=(skin lesion area after skin lesion area-processing before processing)/place Skin lesion area × 100% before reason;
4, test result:
Test result is as shown in Figure 1.As shown in Figure 1, the spring equilibrium water that prepared by the present invention has in terms of cuticula reparation There is apparent effect.Long-time service can maintain skin surface to stablize health.

Claims (10)

1. a kind of spring equilibrium water, which is characterized in that including following component and its parts by weight:
10-20 parts of felwort extracting solution, 20-40 parts of cherry extract, 20-40 parts of mulberries extract, 10-20 parts of wormwood hydrosol, 30-50 parts of 20-40 parts of Purslane extract, 5-12 parts of butanediol, 0.3-0.5 parts of pentanediol and deionized water.
2. spring equilibrium water as described in claim 1, which is characterized in that including following component and its parts by weight:
15 parts of felwort extracting solution, 30 parts of cherry extract, 30 parts of mulberries extract, 15 parts of wormwood hydrosol, Purslane extract 40 parts of 30 parts, 8 parts of butanediol, 0.4 part of pentanediol and deionized water.
3. spring equilibrium water as described in claim 1, which is characterized in that the felwort extracts liquid and preparation method thereof and is:
Weigh dry felwort root, crush to obtain 200 mesh micro mists, by after crushing felwort micro mist and volume fraction be 25- 50% ethyl alcohol is added in reaction kettle, and wherein the mass ratio of ethyl alcohol and felwort micro mist is 8: 1-10: 1, said mixture in After reacting 2-5h under the conditions of 71-79 DEG C in reaction kettle, by products therefrom by decolourizing in decolorizing column, then with 0.2 μm Organic system miillpore filter be filtered by vacuum, finally distill out ethyl alcohol to get.
4. spring equilibrium water as described in claim 1, which is characterized in that the preparation method of the cherry extract is:
Fresh stoning cherry is weighed, is squeezed the juice, gained cherry juice is filtered by the 0.2 μm of water system micropore of product in decolorizing column, obtained Film vacuum filtration to get.
5. spring equilibrium water as described in claim 1, which is characterized in that the preparation method of the mulberries extract is:
Fresh mulberries are weighed, are squeezed the juice, for gained mulberry juice by decolorizing column, it is 2-5% gelatin solutions that volume fraction, which is then added, then Ethyl alcohol is added to acid content up to 70%~80%, the wherein mass ratio of mulberry juice and gelatin solution is 3: 1-6: 1, mulberry juice and second The mass ratio of alcohol is 1: 3-1: 5, and products therefrom stands 6h, is filtered by vacuum with 0.2 μm of water system miillpore filter, finally distills out second Alcohol to get.
6. spring equilibrium water as described in claim 1, which is characterized in that the wormwood hydrosol preparation method is:
Weigh fresh folium artemisiae argyi with pulverizer be ground into folium artemisiae argyi slurries input distillation still in, be added folium artemisiae argyi 5 times of weight of slurries go from Sub- water adds 3-10 zeolites, accesses steam heated still, heats 2-3h, vapor tension control is in 0.2-0.5MPa, heating To distillation temperature in the kettle be 60-70 DEG C when, open condenser be added cooling water, will above-mentioned mixed liquor import oil water separator in point Separate out distillate, resurgent returns in distillation still, collects water layer liquid, finally by gained water layer liquid by decolorizing column to get.
7. spring equilibrium water as described in claim 1, which is characterized in that the preparation method of the Purslane extract is:
The part of stem leaf for weighing fresh purslane, squeezes the juice, and gained purslane extract is by the product that in decolorizing column, obtains with 0.2 μm Water system miillpore filter vacuum filtration to get.
8. the spring equilibrium water as described in claim 3-7 is any, which is characterized in that the decolorizing column extracts for Carb-GCB solid phases Take column.
9. spring equilibrium water as claimed in claim 1 or 2, which is characterized in that the pH value of the equilibrium water is between 4.5-6.5.
10. a kind of preparation method of spring equilibrium water as described in claim 1-9 is any, which is characterized in that including following step Suddenly:
S1 heats water to 60-70 DEG C, and allantoin is added, and stirs to being completely dissolved, obtains allantoin liquid, and it is mixed that pentanediol is then added It closes uniform;
S2 stirs evenly felwort extracting solution, cherry mulberries mixed extract, Purslane extract, wormwood hydrosol, must mix Liquid;
S3 mixed liquor that step S1 is obtained is uniformly mixed with the obtained mixed liquors of step S2 to get.
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CN113520950A (en) * 2021-08-11 2021-10-22 云南白药集团上海科技有限公司 Purslane extract, skin external preparation containing purslane extract, and preparation method and application of purslane extract

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