CN107049896A - Stem of noble dendrobium multiple-effect stoste and preparation method thereof - Google Patents

Stem of noble dendrobium multiple-effect stoste and preparation method thereof Download PDF

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CN107049896A
CN107049896A CN201710248206.XA CN201710248206A CN107049896A CN 107049896 A CN107049896 A CN 107049896A CN 201710248206 A CN201710248206 A CN 201710248206A CN 107049896 A CN107049896 A CN 107049896A
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parts
extract
stem
skin
noble dendrobium
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陀珊珊
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Guangxi Rongxian County Tianshun Dendrobium Co Ltd
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Guangxi Rongxian County Tianshun Dendrobium Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses stem of noble dendrobium multiple-effect stoste and preparation method thereof, belong to cosmetic field.This stem of noble dendrobium multiple-effect stoste is made up of the following raw material:Dendrobium candidum extract, glycosyl trehalose, ceramide, Sodium Hyaluronate, butanediol, glycerine, 1,2 pentanediol, Phenoxyethanol, hydrogenated starch hydrolysate, methyl propanediol, marine algae extract, turn round thorn Cactus Pedicel extract, Fructus Cucumidis sativi extract, garment or robe made of feathers leaf extract, lecithin and water, by the way that each raw material is mixed to prepare.This stem of noble dendrobium stoste is nontoxic to have no side effect without any harmful chemical addition agent, and many effects of function are good, is particularly suitable for maintenance because of all kinds of skin problems for appearance of staying up late.

Description

Stem of noble dendrobium multiple-effect stoste and preparation method thereof
Technical field
The present invention relates to cosmetic field, and in particular to stem of noble dendrobium multiple-effect stoste and preparation method thereof.
Background technology
With the quickening of people's rhythm of life, many people are because the situation of staying up late occurs in work, study, dinner party etc..And endure Injury of the night to skin is very big, and common skin symptom of staying up late has following aspects:First, enlarged pores, grease can be allowed by staying up late Hypersecretion, can also make skin become coarse lackluster, and pore also becomes increasingly thick;2nd, long small pox, kidney can be accelerated by staying up late The secretion of upper parathyrine, allows sebum to increase and block pore, causes blackhead and small pox;3rd, the colour of skin is obscure, and midnight stays up, The blood circulation speed of skin epidermis can be slowed down, skin can seem obscure, turned to be yellow, lack bright color;4th, decortication length is dried Wrinkle, after staying up late, because skin blood circulation weakens, endocrinopathy makes skin dry and astringent, it is easy to long wrinkle, or even occurs The phenomenon of local decortication;5th, profit is unbalance, stays up late for a long time, irregular sleep, can cause endocrinopathy, the profit of skin It is unbalance so that fat secretion increase, and water-retaining property is not good, skin easily relaxes.
In order to save the skin problem brought because staying up late, many people can strengthen the maintenance to oneself skin and nursing, and Most common skin care method is maintained using skin care item.Skin care item species is various, there is face cream, emulsion, facial mask, elite Liquid, toner etc., effect is different.The function of skin care item can be divided into moisturizing, whitening, nti-freckle, skin of releiving, exclusion skin poison Element, improve the obscure and drying of the colour of skin, elastic force moisturizing, lifting of compacting, wrinkle resistant anti-aging, prevent and treat dark sore etc..And in the market Skin care item be substantially that performance is more single, only effect in terms of certain, it is impossible to while solving the various problems that skin occurs, no The demand of current consumer can be met.
In order to reach corresponding effect, most of skin care item contain various harmful additives, commonly use six big chemistry additions Agent:1st, preservative, is one of arch-criminal of skin aging, and some preservatives are even more carcinogen, and the skin care item without preservative With high costs, market is rarely seen;2nd, hormone and heavy metal, can cause Skin pigmentation, produce dependence syndrome, once disable such shield Skin product, will appear from the inflammation such as pore expansion and allergy;3rd, essence, allergic, content can be caused with the collective effect of ultraviolet Higher, skin injury is more serious;4th, fluorescer, it is difficult to by body metabolism, long term accumulation can make immunity degradation, can seriously cause Skin Cell rises in value extremely, occurs canceration;5th, alcohol, can make skin occur photosensitized reaction, cause pigment to aggravate, appearance can not disappear The skin speckle removed;6th, mineral oil, it is impossible to by skin metabolism, hinders skin to absorb vitamin, so as to dry, obscure, hair occur The problems such as hole plug, inflammation.Consumer is after such product is used for a long time, and allergic reaction or pigment deposition occurs in skin, long Phase is big to skin damage using meeting, and more serious even induces other diseases.
The content of the invention
The purpose of the present invention is that there is provided a kind of stem of noble dendrobium multiple-effect stoste and its preparation in view of the above-mentioned problems existing in the prior art Method, this stem of noble dendrobium stoste is nontoxic to have no side effect without any harmful chemical addition agent, and many effects of function are good, It is particularly suitable for maintenance because of all kinds of skin problems for appearance of staying up late.
To reach above-mentioned purpose, the technical solution adopted by the present invention is as follows:
Stem of noble dendrobium multiple-effect stoste, is made up of the raw material of following parts by weight:30-40 parts of dendrobium candidum extract, glycosyl marine alga It is sugared 1-2 parts, 0.3-0.5 parts of ceramide, 0.01-0.03 parts of Sodium Hyaluronate, 2-3 parts of butanediol, 1-2 parts of glycerine, 1,2- penta 0.5-1 parts of glycol, 0.2-0.5 parts of Phenoxyethanol, 0.2-0.5 parts of hydrogenated starch hydrolysate, 0.1-0.3 parts of methyl propanediol, sea 1-2 parts of algae extract, turns round 0.5-1 parts of Cactus Pedicel extract of thorn, 0.5-1 parts of Fructus Cucumidis sativi extract, garment or robe made of feathers leaf extract 0.2- 0.5 part, 0.1-0.3 parts of lecithin, 50-60 parts of water.
Preferably, the stem of noble dendrobium multiple-effect stoste is made up of the raw material of following parts by weight:Dendrobium candidum extract 35-38 Part, 1.2-1.5 parts of glycosyl trehalose, 0.3-0.4 parts of ceramide, 0.01-0.03 parts of Sodium Hyaluronate, 2-3 parts of butanediol is sweet It is oily 1-2 parts, 1,2- 0.6-0.8 parts of pentanediol, 0.3-0.4 parts of Phenoxyethanol, 0.2-0.3 parts of hydrogenated starch hydrolysate, methyl-prop 0.2-0.3 parts of glycol, 1.5-1.7 parts of marine algae extract turns round 0.6-0.8 parts of Cactus Pedicel extract of thorn, Fructus Cucumidis sativi extract 0.6- 0.7 part, 0.3-0.4 parts of garment or robe made of feathers leaf extract, 0.1-0.2 parts of lecithin, 55-58 parts of water.
Preferably, the stem of noble dendrobium multiple-effect stoste is made up of the raw material of following parts by weight:By the original of following parts by weight Material is made:37 parts of dendrobium candidum extract, 1.3 parts of glycosyl trehalose, 0.35 part of ceramide, 0.02 part of Sodium Hyaluronate, fourth 2 parts of glycol, 1.5 parts of glycerine, 1,2- 0.7 part of pentanediol, 0.35 part of Phenoxyethanol, 0.2 part of hydrogenated starch hydrolysate, methyl-prop two 0.25 part of alcohol, 1.6 parts of marine algae extract turns round 0.7 part of thorn Cactus Pedicel extract, 0.6 part of Fructus Cucumidis sativi extract, garment or robe made of feathers blade of grass is extracted 0.3 part of thing, 0.15 part of lecithin, 56 parts of water.
The preparation method of above-mentioned stem of noble dendrobium multiple-effect stoste, comprises the following steps:
(1) preparation of dendrobium candidum extract:The stem of dendrobium candidum is taken, 1-2cm section shape is cut into, alcohol reflux is added and carries The mass ratio for taking the ethanol and dendrobium candidum stem twice, added every time is 4-5:1, it is for the first time 40%-50% with volumetric concentration Ethanol extract 2 hours, second is extracted 1 hour with volumetric concentration for 30% ethanol, and filtering is obtained after filtrate, merging filtrate Concentrated, relative density is 1.10-1.20 thick paste when being concentrated into 60 DEG C, and the quality of water, thick paste and water is added in thick paste Than for 1:2-4, stands 10-15 hours after stirring, takes supernatant to be concentrated, relative density is when being concentrated into 60 DEG C 1.02-1.05 concentrate, as dendrobium candidum extract;
(2) by glycosyl trehalose, ceramide, Sodium Hyaluronate, butanediol, glycerine, 1,2- pentanediols, Phenoxyethanol, Hydrogenated starch hydrolysate, methyl propanediol and lecithin are added to the water, and after being stirred at 70-80 DEG C, naturally cool to room Temperature, after standing 1-2 hours, obtains mixed liquor A;
(3) mixed liquor A is heated to 40-50 DEG C, adds dendrobium candidum extract, marine algae extract, turns round thorn Cactus Pedicel Extract, Fructus Cucumidis sativi extract, garment or robe made of feathers leaf extract, obtain mixed liquid B after stirring and dissolving is uniform, be incubated 10-15 minutes, natural Room temperature is cooled to, stem of noble dendrobium multiple-effect stoste is obtained, bottling packing obtains finished product.
Above-mentioned technical proposal, preferably, in the step (1), the quality of the ethanol added every time and dendrobium candidum stem Than for 4.6:1.
Above-mentioned technical proposal, preferably, in the step (1), the mass ratio of thick paste and water is 1:3.5.
Above-mentioned technical proposal, preferably, in the step (2), in the manufacturing process of mixed liquor A, whipping temp is 75 DEG C, time of repose is 1.5 hours.
The performance of used part primary raw material component and effect are as follows in the formula of the present invention:
Dendrobium candidum extract:Containing dendrobium polysaccharide, abundant amino acid, micro- and substantial amounts of colloid, with superpower Moisturizing water lock power, effectively resist microgroove generation, and be effectively improved existing microgroove, nourishes rough skin makes skin more gloss developing;It is resistant to Bacterium anti-inflammatory, the problems such as being effectively improved allergic, long small pox, bellding light improves cutaneous immunisation power;The a large amount of colloids being rich in, can The collagen in skin is supplemented, skin damage is repaired, allows skin to recover original elasticity and gloss;It is glutinous in dendrobium candidum stem Property material be a kind of natural antioxidant, can delay skin aging.
Glycosyl trehalose:It is a kind of safe and reliable natural carbohydrate, in high temperature, high and cold, hyperosmosis and dry dehydration etc. The diaphragm of uniqueness can be formed in cell surface under severe environmental conditions, flesh bottom moisture can be effectively pinned, the damage of moisture is reduced Lose.
Ceramide:With penetration free from worldly cares, the fibroblast of aging can be stimulated, protection skin collagen matter network It is complete unified, the sustainable development of aging is prevented, skin moisture holding capacity is improved, wrinkle is reduced, strengthens skin elasticity, delaying skin declines Always, make skin young.Principle:Ceramide is the master for being present in lipoid between the outermost corneocyte of our human body skins Composition is wanted, the water that can be penetrated into quickly in skin, and cuticula is combined, form a kind of network structure, pin moisture, reduce epidermis Water loss, as the age increases, the lipid synthesis of skin declines, and ceramide content is reduced in cuticula, with skin fat Matter content is reduced, and skin barrier function declines.And ceramide can increase horny layer of epidermis thickness, skin moisture holding capacity is improved, Wrinkle is reduced, strengthens skin elasticity, delay skin aging.
Hydrogenated starch hydrolysate:There is provided by Hangzhou Wang Yuan Science and Technology Ltd.s, this hydrogenated starch hydrolysate has very strong Hydrophily, moisture-keeping functions are powerful, with the secretion of balance skin grease, can improve the slipping of skin, suppress pachylosis;Have Anti-inflammatory effect, stimulates skin without any, can reduce the overall stimulation of formula system;Ultraviolet injury cell is avoided, Due to ultraviolet irradiation, cell will be sustained damage, and cell number is reduced, by adding hydrogenated starch hydrolysate, can mitigate thin Born of the same parents' extent of damage.
Marine algae extract:There is provided by Shaanxi Zhong Xin Bioisystech Co., Ltd, be a kind of pure natural marine organisms product, All features are all from marine alga in itself.Marine alga contains various active compound, seems alditol derivative, the smart polymer of algae etc., The ossein of similar gels can be produced with human body protein binding, strengthens the water lock power of skin with this, increases the moistening effect of skin Greatly.Meanwhile, marine alga plays the role of activation hair follicle, purification pore again, and cement sense can suction out many debris, adjust pore size, Skin is helped to realize water and oil balance.In marine algae extract, contain the alditol such as amino acid, vitamin and mucopolysaccharide derivative and algae essence Polymer, there is good moisturizing, lubrication and wrinkle resistant to skin, in addition, iodine-containing seaweed, iodine has bactericidal antiphlogistic effect, So marine alga is the good disinfecting skin-care agent of skin again.Contain phycocolloid acid, crude protein, multivitamin, enzyme and micro member in it Element, after such nutrition absorbs through skin, can reduce surface blood fat, promote surface skin hematopoiesis function.In addition marine algae extract is also Containing substantial amounts of anion, fibrocyte can be stimulated to generate collagen and elastin laminin, promote the metabolism of skin, resisted Wrinkle, anti-aging.
Turn round thorn Cactus Pedicel extract:There is provided, be turned into good antioxygen by Xi'an Bioisystech Co., Ltd of Tianrui With the remarkable efficacy also with efficient moisturizing, radiation proof ensures high nutrition, high-purity and the height of natural organofunctional composition Activity, makes skin from the injury of ultraviolet and computer, TV and mobile phone radiation.
Fructus Cucumidis sativi extract:There is provided by Xi'an Bioisystech Co., Ltd of Tianrui, with good performance of keeping humidity, containing abundant Amino acid, also contain vitamin A, C, E and K, help to repair such as acne or other sensitive skin problems.Fructus Cucumidis sativi extract In also contain various mineral matters, including magnesium, potassium, silicon etc. can help to reduce the appearance of microgroove and wrinkle.
Garment or robe made of feathers leaf extract:There is provided by Xi'an Bioisystech Co., Ltd of Tianrui, with anti-oxidant and removing free radical Effect, can suppress to participate in the activity of the TYR enzyme of melanin biosynthesis, be formed from source prevention, barrier pigment color spot, Can more make stubbornness age spot it is thin out, diminish, whitening simultaneously anti-aging.
Lecithin:With moisturizing, mild action is pacified.Additionally since lecithin can absorb moisture so can from air Kept the skin wet for skin, meet the moisturizing demand of skin.Lecithin has the function of uniqueness can be by the nutrient of other additives Bring skin inner layer into, be directly entered in blood vessel and cell.Lecithin also has natural emulsified, thick, stablizing effect.
Beneficial effect:The stem of noble dendrobium multiple-effect stoste that the present invention is provided, raw material is high activity composition, without any artificial fragrant The harmful substances such as essence, pigment, alcohol, hormone, chemical preservative, emulsifying agent, fluorescer, heavy metal, safe and non-stimulating, nontoxic nothing Evil is without any side effects;This stem of noble dendrobium stoste can have multiple efficacies concurrently simultaneously by the synergy of the stem of noble dendrobium and other various raw materials, Maintenance of releiving is carried out to skin, makes skin is obscure to highlight, spot desalination, water humidity lifting, slackness is compacted, can effectively be solved simultaneously Certainly skin oil-water is unbalance, the colour of skin is obscure, dry decortication, long wrinkle, enlarged pores, long small pox the problems such as.
Stem of noble dendrobium composition in this stem of noble dendrobium multiple-effect stoste is compounded according to a certain percentage with other each components, passes through each component In contained active ingredient mutual cooperation, multiple efficacies can be had concurrently simultaneously.Wherein, the dendrobium candidum extract in component contains the stem of noble dendrobium Polysaccharide, abundant amino acid, micro- and substantial amounts of colloid, with superpower moisturizing water lock power, coordinate glycosyl trehalose to make With, be able to can be formed in cell surface uniqueness diaphragm, reduce moisture loss, moisture of skin can be effectively safeguarded, in component The marine algae extract of addition plays the role of activation hair follicle, purification pore, can keep skin oil-water balance, reduce pore;And add Ceramide there is very strong penetration, the fibroblast of aging can be stimulated, skin moisture holding capacity is improved, wrinkle is reduced, Strengthen skin elasticity;, can be pre- by moisturizing by using cooperatively for dendrobium candidum extract, glycosyl trehalose and ceramide Anti-wrinkle, and the wrinkle produced, delay skin aging can be desalinated.
Hydrogenated starch hydrolysate in component can mitigate and avoid ultraviolet injury cell, prevent the generation of color spot, and Turning round thorn Cactus Pedicel extract has good antioxidation, and the remarkable efficacy with radiation proof makes skin from ultraviolet With the injury of computer, TV and mobile phone radiation, garment or robe made of feathers leaf extract can suppress to participate in the TYR of melanin biosynthesis The activity of enzyme, from source prevention, barrier pigment color spot formed, by hydrogenated starch hydrolysate, turn round thorn Cactus Pedicel extract and The mutual synergy of garment or robe made of feathers leaf extract, can effectively prevent from and desalinate to increase from ultraviolet, electric type radiation and age Etc. the deposition of the pigment caused, make that color spot is thin out, diminish, bright color can whitening anti-aging simultaneously.
Contain iodine in marine algae extract in component, iodine has bactericidal antiphlogistic effect, so making with good disinfecting skin-care With being coordinated with Fructus Cucumidis sativi extract, Fructus Cucumidis sativi extract contains abundant amino acid, also contain vitamin A, C, E and K, help In repairing such as acne or other sensitive skin problems, and dendrobium candidum extract energy anti-inflammation, be effectively improved it is allergic, The problems such as long small pox, bellding light, the generation of small pox can effectively be prevented by the mutual cooperation of three, can be to the small pox that has produced Eliminated, and desalinate acne print.
Active principle in the present invention is non-stimulated material, is matched somebody with somebody while the hydrogenated starch hydrolysate in component can be reduced The overall stimulation of cube system, and lecithin can bring the nutrient of other additives into skin inner layer, be directly entered in skin, Other lecithin, which has, pacifies gentle effect, and both, which combine, not only makes this stem of noble dendrobium multiple-effect stoste each component mutually merge, fully Various effects are played, and ensure that the reparation of this stoste is releived, it is gentle non-stimulated, to skins such as various sensitive fleshes, red blood silk, small pox fleshes Matter is applicable.
Embodiment
With reference to specific embodiment, the present invention is described further.
Embodiment 1
Stem of noble dendrobium multiple-effect stoste, is made up of the raw material of following parts by weight:37 parts of dendrobium candidum extract, glycosyl trehalose 1.3 parts, 0.35 part of ceramide, 0.02 part of Sodium Hyaluronate, 2 parts of butanediol, 1.5 parts of glycerine, 1,2- 0.7 part of pentanediol, benzene 0.35 part of oxyethanol, 0.2 part of hydrogenated starch hydrolysate, 0.25 part of methyl propanediol, 1.6 parts of marine algae extract turns round thorn cactus 0.7 part of stem extraction, 0.6 part of Fructus Cucumidis sativi extract, 0.3 part of garment or robe made of feathers leaf extract, 0.15 part of lecithin, 56 parts of water.
The preparation method of above-mentioned stem of noble dendrobium multiple-effect stoste, comprises the following steps:
(1) preparation of dendrobium candidum extract:The stem of dendrobium candidum is taken, 1-2cm section shape is cut into, alcohol reflux is added and carries The mass ratio for taking the ethanol and dendrobium candidum stem twice, added every time is 4.6:1, for the first time with the ethanol that volumetric concentration is 50% Extract 2 hours, second is extracted 1 hour with volumetric concentration for 30% ethanol, filtering, obtain carried out after filtrate, merging filtrate it is dense Contracting, relative density is 1.15 thick paste when being concentrated into 60 DEG C, adds water in thick paste, and the mass ratio of thick paste and water is 1:3.5, stir Mix uniform rear standing 12 hours, take supernatant to be concentrated, relative density is 1.03 concentrate, as iron when being concentrated into 60 DEG C Skin Herba Dendrobii extract;
(2) by glycosyl trehalose, ceramide, Sodium Hyaluronate, butanediol, glycerine, 1,2- pentanediols, Phenoxyethanol, Hydrogenated starch hydrolysate, methyl propanediol and lecithin are added to the water, and after being stirred at 75 DEG C, naturally cool to room temperature, After standing 1.5 hours, mixed liquor A is obtained;
(3) mixed liquor A is heated to 43 DEG C, adds dendrobium candidum extract, marine algae extract, turns round thorn Cactus Pedicel extraction Thing, Fructus Cucumidis sativi extract, garment or robe made of feathers leaf extract, obtain mixed liquid B after stirring and dissolving is uniform, be incubated 12 minutes, naturally cool to Room temperature, obtains stem of noble dendrobium multiple-effect stoste, and bottling packing obtains finished product.
Embodiment 2
Stem of noble dendrobium multiple-effect stoste, is made up of the raw material of following parts by weight:30 parts of dendrobium candidum extract, glycosyl trehalose 1 Part, 0.3 part of ceramide, 0.01 part of Sodium Hyaluronate, 2 parts of butanediol, 1 part of glycerine, 1,2- 0.5 part of pentanediol, Phenoxyethanol 0.2 part, 0.2 part of hydrogenated starch hydrolysate, 0.1 part of methyl propanediol, 1 part of marine algae extract turns round thorn Cactus Pedicel extract 0.5 Part, 0.5 part of Fructus Cucumidis sativi extract, 0.2 part of garment or robe made of feathers leaf extract, 0.1 part of lecithin, 50 parts of water.
The preparation method of above-mentioned stem of noble dendrobium multiple-effect stoste, comprises the following steps:
(1) preparation of dendrobium candidum extract:The stem of dendrobium candidum is taken, 1-2cm section shape is cut into, alcohol reflux is added and carries The mass ratio for taking the ethanol and dendrobium candidum stem twice, added every time is 4:1, carried for the first time with volumetric concentration for 40% ethanol Take 2 hours, extracted 1 hour for 30% ethanol with volumetric concentration for the second time, filtering is concentrated after obtaining filtrate, merging filtrate, Relative density is 1.10 thick paste when being concentrated into 60 DEG C, adds water in thick paste, and the mass ratio of thick paste and water is 1:2, stirring is equal 10 hours are stood after even, takes supernatant to be concentrated, relative density is 1.02 concentrate, as iron sheet stone when being concentrated into 60 DEG C Dry measure used in former times extract;
(2) by glycosyl trehalose, ceramide, Sodium Hyaluronate, butanediol, glycerine, 1,2- pentanediols, Phenoxyethanol, Hydrogenated starch hydrolysate, methyl propanediol and lecithin are added to the water, and after being stirred at 70 DEG C, naturally cool to room temperature, After standing 1-2 hours, mixed liquor A is obtained;
(3) mixed liquor A is heated to 40 DEG C, adds dendrobium candidum extract, marine algae extract, turns round thorn Cactus Pedicel extraction Thing, Fructus Cucumidis sativi extract, garment or robe made of feathers leaf extract, obtain mixed liquid B after stirring and dissolving is uniform, be incubated 10 minutes, naturally cool to Room temperature, obtains stem of noble dendrobium multiple-effect stoste, and bottling packing obtains finished product.
Embodiment 3
Stem of noble dendrobium multiple-effect stoste, is made up of the raw material of following parts by weight:40 parts of dendrobium candidum extract, glycosyl trehalose 2 Part, 0.5 part of ceramide, 0.03 part of Sodium Hyaluronate, 3 parts of butanediol, 2 parts of glycerine, 1,2- 1 part of pentanediol, Phenoxyethanol 0.5 Part, 0.5 part of hydrogenated starch hydrolysate, 0.3 part of methyl propanediol, 2 parts of marine algae extract turns round 1 part of thorn Cactus Pedicel extract, yellow 1 part of melon extract, 0.5 part of garment or robe made of feathers leaf extract, 0.3 part of lecithin, 60 parts of water.
The preparation method of above-mentioned stem of noble dendrobium multiple-effect stoste, comprises the following steps:
(1) preparation of dendrobium candidum extract:The stem of dendrobium candidum is taken, 1-2cm section shape is cut into, alcohol reflux is added and carries The mass ratio for taking the ethanol and dendrobium candidum stem twice, added every time is 5:1, carried for the first time with volumetric concentration for 50% ethanol Take 2 hours, extracted 1 hour for 30% ethanol with volumetric concentration for the second time, filtering is concentrated after obtaining filtrate, merging filtrate, Relative density is 1.20 thick paste when being concentrated into 60 DEG C, adds water in thick paste, and the mass ratio of thick paste and water is 1:4, stirring is equal 15 hours are stood after even, takes supernatant to be concentrated, relative density is 1.05 concentrate, as iron sheet stone when being concentrated into 60 DEG C Dry measure used in former times extract;
(2) by glycosyl trehalose, ceramide, Sodium Hyaluronate, butanediol, glycerine, 1,2- pentanediols, Phenoxyethanol, Hydrogenated starch hydrolysate, methyl propanediol and lecithin are added to the water, and after being stirred at 80 DEG C, naturally cool to room temperature, After standing 2 hours, mixed liquor A is obtained;
(3) mixed liquor A is heated to 50 DEG C, adds dendrobium candidum extract, marine algae extract, turns round thorn Cactus Pedicel extraction Thing, Fructus Cucumidis sativi extract, garment or robe made of feathers leaf extract, obtain mixed liquid B after stirring and dissolving is uniform, be incubated 15 minutes, naturally cool to Room temperature, obtains stem of noble dendrobium multiple-effect stoste, and bottling packing obtains finished product.
Embodiment 4
Stem of noble dendrobium multiple-effect stoste, it is characterised in that be made up of the raw material of following parts by weight:35 parts of dendrobium candidum extract, 1.2 parts of glycosyl trehalose, 0.3 part of ceramide, 0.01 part of Sodium Hyaluronate, 2 parts of butanediol, 1 part of glycerine, 1,2- pentanediol 0.6 part, 0.3-0.4 parts of Phenoxyethanol, 0.2 part of hydrogenated starch hydrolysate, 0.2 part of methyl propanediol, 1.5 parts of marine algae extract, Turn round 0.6 part of thorn Cactus Pedicel extract, 0.6 part of Fructus Cucumidis sativi extract, 0.3 part of garment or robe made of feathers leaf extract, 0.1 part of lecithin, water 55 Part.
The preparation method of above-mentioned stem of noble dendrobium multiple-effect stoste, comprises the following steps:
(1) preparation of dendrobium candidum extract:The stem of dendrobium candidum is taken, 1-2cm section shape is cut into, alcohol reflux is added and carries The mass ratio for taking the ethanol and dendrobium candidum stem twice, added every time is 4.3:1, for the first time with the ethanol that volumetric concentration is 50% Extract 2 hours, second is extracted 1 hour with volumetric concentration for 30% ethanol, filtering, obtain carried out after filtrate, merging filtrate it is dense Contracting, relative density is 1.10 thick paste when being concentrated into 60 DEG C, adds water in thick paste, and the mass ratio of thick paste and water is 1:3, stirring 13 hours are stood after uniform, takes supernatant to be concentrated, relative density is 1.04 concentrate, as iron sheet when being concentrated into 60 DEG C Herba Dendrobii extract;
(2) by glycosyl trehalose, ceramide, Sodium Hyaluronate, butanediol, glycerine, 1,2- pentanediols, Phenoxyethanol, Hydrogenated starch hydrolysate, methyl propanediol and lecithin are added to the water, and after being stirred at 75 DEG C, naturally cool to room temperature, After standing 1 hour, mixed liquor A is obtained;
(3) mixed liquor A is heated to 45 DEG C, adds dendrobium candidum extract, marine algae extract, turns round thorn Cactus Pedicel extraction Thing, Fructus Cucumidis sativi extract, garment or robe made of feathers leaf extract, obtain mixed liquid B after stirring and dissolving is uniform, be incubated 13 minutes, naturally cool to Room temperature, obtains stem of noble dendrobium multiple-effect stoste, and bottling packing obtains finished product.
Example 1 is to each 2 bottles of the stem of noble dendrobium multiple-effect stoste of embodiment 4, and 8 bottles altogether, every bottle of 15ml is sent to Guangdong Province Zhuhai City's mass metrology supervisory detection is tested, and assay is shown in Tables 1 and 2.
The health chemical testing result of table 1
Inspection project Limit value Assay
Mercury (mg/kg) ﹤ 1 Do not detect
Arsenic (mg/kg) ﹤ 10 Do not detect
Lead (mg/kg) ﹤ 40 Do not detect
The Micro biological Tests result of table 2
Interpretation of result:According to《Cosmetics health specification》Wholesomeness examine, 1, health chemical testing:Lead, arsenic, mercury Testing result meets the requirements;2nd, microbiological Test:Total plate count, excrement large intestine group, staphylococcus aureus, P. aeruginosa The projects such as bacterium meet the requirements.The content of beary metal that this stem of noble dendrobium multiple-effect stoste is can be seen that from the result of Tables 1 and 2 is not Detection, has been not added with heavy metal, and the detection value of total plate count yeast and mold sum is very small, excrement colibacillus group, gold Staphylococcus aureus, pseudomonas aeruginosa are not detect, illustrate that this stem of noble dendrobium multiple-effect stoste is fool proof reliable.
The stem of noble dendrobium multiple-effect stoste of the present invention has done water content experiment and multiple-effect function test in addition to doing above-mentioned inspection, also.
Water content is tested:Tested using Skin Moisture Test Pen, it is as a result as follows:The stem of noble dendrobium multiple-effect of the present invention is not used Before stoste, face skin initial water is divided into 23.8%;After smearing skin 5 minutes with stem of noble dendrobium multiple-effect stoste made from embodiment 1, survey The moisture for trying same place skin is 42.0%;Skin moisture is 36.7% after 3 hours.As can be seen from the above results, this stem of noble dendrobium Multiple-effect stoste can not only quickly supplement sufficient moisture to skin, and can long-acting moisturizing, the long-time water profit of holding skin.
Multiple-effect function test
Test number:80 people;Age:18-50 Sui;Sex:The people of female 60, male 20 people;Health status:Subject is without skin disease Allergies;Facial skin situation:Dry 30 people of decortication, the long people of small pox 30, the heavy people of spot 20 of pigment.
Test process:Embodiment 1 is into embodiment 4, and each embodiment selects 20 people to be tried out, and female 15 is contained in 20 people People, male 5 people, trier uses stem of noble dendrobium multiple-effect stoste twice daily, once in the morning and once at night, after face is cleaned, by stem of noble dendrobium multiple-effect stoste Face is applied to, pressing absorbs, and tries out one month, concrete outcome is as shown in table 3.
Table 3
From table 3 it can be seen that the stem of noble dendrobium multiple-effect stoste that the present invention is provided effectively can carry out maintenance to various problem skins.
Typical case:
Mr. Wang, 25 years old, office manager, due to the outgoing dinner party of need of work, often stayed up late, worked and rested irregular, long on the face More small pox, continues not feeling any better for 2 months, and leaves many acne prints, influence image.It is made using the embodiment of the present invention 1 The stem of noble dendrobium multiple-effect stoste obtained, once in the morning and once at night, after one week, small pox is significantly reduced, after one month, acne on the face Acne disappears substantially, and acne print is substantially desalinated.
Mrs Zhu, 48 years old, on-line shop storekeeper, due to doing on-line selling, worked and rested irregular throughout the year, and frequent 1 point of morning sleeps Feel, skin of face is dried, and has more color spot, skin is more obscure, there is deeper wrinkle, it appears be wan and sallow aged.Using of the invention real Apply stem of noble dendrobium multiple-effect stoste made from example 2, daily use 2 times, shoaled using wrinkle after one month, color spot tail off it is thin out, skin compared with Water moistens and than using preceding more glossy, more aobvious youth.
Mrs Zhao, 35 years old, project was caught up with project leader, often overtime work, and the decortication of dry skin peeling has more microgroove, skin Skin is intense darkness without light, using stem of noble dendrobium multiple-effect stoste made from the embodiment of the present invention 3, daily using twice, after three days, and peeling takes off Skin situation disappears, and skin becomes water and moistens glossy, and microgroove shoals.
The above described is only a preferred embodiment of the present invention, any formal limitation not is done to the present invention, therefore All contents without departing from technical solution of the present invention, the technical spirit according to the present invention any is simply repaiied to made for any of the above embodiments Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.

Claims (7)

1. stem of noble dendrobium multiple-effect stoste, it is characterised in that be made up of the raw material of following parts by weight:30-40 parts of dendrobium candidum extract, 1-2 parts of glycosyl trehalose, 0.3-0.5 parts of ceramide, 0.01-0.03 parts of Sodium Hyaluronate, 2-3 parts of butanediol, glycerine 1-2 Part, 1,2- 0.5-1 parts of pentanediol, 0.2-0.5 parts of Phenoxyethanol, 0.2-0.5 parts of hydrogenated starch hydrolysate, methyl propanediol 0.1- 0.3 part, 1-2 parts of marine algae extract is turned round and pierces 0.5-1 parts of Cactus Pedicel extract, 0.5-1 parts of Fructus Cucumidis sativi extract, and garment or robe made of feathers blade of grass is carried Take 0.2-0.5 parts of thing, 0.1-0.3 parts of lecithin, 50-60 parts of water.
2. stem of noble dendrobium multiple-effect stoste as claimed in claim 1, it is characterised in that be made up of the raw material of following parts by weight:Iron sheet 35-38 parts of Herba Dendrobii extract, 1.2-1.5 parts of glycosyl trehalose, 0.3-0.4 parts of ceramide, Sodium Hyaluronate 0.01-0.03 Part, 2-3 parts of butanediol, 1-2 parts of glycerine, 1,2- 0.6-0.8 parts of pentanediol, 0.3-0.4 parts of Phenoxyethanol, hydrogenated starch hydrolysate 0.2-0.3 parts, 0.2-0.3 parts of methyl propanediol, 1.5-1.7 parts of marine algae extract turns round thorn Cactus Pedicel extract 0.6-0.8 Part, 0.6-0.7 parts of Fructus Cucumidis sativi extract, 0.3-0.4 parts of garment or robe made of feathers leaf extract, 0.1-0.2 parts of lecithin, 55-58 parts of water.
3. stem of noble dendrobium multiple-effect stoste as claimed in claim 2, it is characterised in that be made up of the raw material of following parts by weight:Iron sheet 37 parts of Herba Dendrobii extract, 1.3 parts of glycosyl trehalose, 0.35 part of ceramide, 0.02 part of Sodium Hyaluronate, 2 parts of butanediol, glycerine 1.5 parts, 1,2- 0.7 part of pentanediol, 0.35 part of Phenoxyethanol, 0.2 part of hydrogenated starch hydrolysate, 0.25 part of methyl propanediol, sea 1.6 parts of algae extract, turns round 0.7 part of thorn Cactus Pedicel extract, 0.6 part of Fructus Cucumidis sativi extract, 0.3 part of garment or robe made of feathers leaf extract, ovum .15 parts of phosphatidase 0,56 parts of water.
4. the preparation method of stem of noble dendrobium multiple-effect stoste as described in claim any one of 1-3, it is characterised in that comprise the following steps:
(1) preparation of dendrobium candidum extract:The stem of dendrobium candidum is taken, 1-2cm section shape is cut into, alcohol reflux is added and extracts two Secondary, the mass ratio of the ethanol added every time and dendrobium candidum stem is 4-5:1, the second for being for the first time 40%-50% with volumetric concentration Alcohol extracting 2 hours, is extracted 1 hour, filtering with volumetric concentration for 30% ethanol for the second time, obtains progress after filtrate, merging filtrate Concentration, relative density is 1.10-1.20 thick paste when being concentrated into 60 DEG C, adds water in thick paste, and the mass ratio of thick paste and water is 1:2-4, stands 10-15 hours after stirring, takes supernatant to be concentrated, and relative density is 1.02- when being concentrated into 60 DEG C 1.05 concentrate, as dendrobium candidum extract;
(2) by glycosyl trehalose, ceramide, Sodium Hyaluronate, butanediol, glycerine, 1,2- pentanediols, Phenoxyethanol, hydrogenation Glucidtemns, methyl propanediol and lecithin are added to the water, after being stirred at 70-80 DEG C, naturally cool to room temperature, quiet Put after 1-2 hours, obtain mixed liquor A;
(3) mixed liquor A is heated to 40-50 DEG C, adds dendrobium candidum extract, marine algae extract, turns round thorn Cactus Pedicel extraction Thing, Fructus Cucumidis sativi extract, garment or robe made of feathers leaf extract, obtain mixed liquid B after stirring and dissolving is uniform, be incubated 10-15 minutes, natural cooling To room temperature, stem of noble dendrobium multiple-effect stoste is obtained, bottling packing obtains finished product.
5. the preparation method of stem of noble dendrobium multiple-effect stoste as claimed in claim 4, it is characterised in that:In the step (1), add every time The mass ratio of ethanol and dendrobium candidum stem be 4.6:1.
6. the preparation method of stem of noble dendrobium multiple-effect stoste as claimed in claim 4, it is characterised in that:In the step (1), thick paste and water Mass ratio be 1:3.5.
7. the preparation method of stem of noble dendrobium multiple-effect stoste as claimed in claim 4, it is characterised in that:In the step (2), mixed liquor A Manufacturing process in, whipping temp be 75 DEG C, time of repose be 1.5 hours.
CN201710248206.XA 2017-04-17 2017-04-17 Stem of noble dendrobium multiple-effect stoste and preparation method thereof Pending CN107049896A (en)

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CN108245465A (en) * 2018-03-01 2018-07-06 安徽中升生物科技有限公司 A kind of Dendrobidium huoshanness facial treatment essence liquid and preparation method thereof
CN109276519A (en) * 2018-11-22 2019-01-29 广州睿森生物科技有限公司 A kind of paris polyphylla fermenation raw liquid and its preparation method and application
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CN111514059A (en) * 2020-05-26 2020-08-11 佛山市谷邦生物科技有限公司 Ceramide compound skin-soothing moisturizing factor and facial mask thereof
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107789282A (en) * 2017-11-22 2018-03-13 天津市蓝宝石化妆品有限公司 A kind of skin care item containing dendrobium candidum extract and plant whitening element and its preparation method and application
CN107875089A (en) * 2017-11-22 2018-04-06 天津市蓝宝石化妆品有限公司 A kind of skin care item containing dendrobium candidum and its preparation method and application
CN108245465A (en) * 2018-03-01 2018-07-06 安徽中升生物科技有限公司 A kind of Dendrobidium huoshanness facial treatment essence liquid and preparation method thereof
CN109276519A (en) * 2018-11-22 2019-01-29 广州睿森生物科技有限公司 A kind of paris polyphylla fermenation raw liquid and its preparation method and application
CN109276519B (en) * 2018-11-22 2021-06-29 广州睿森生物科技有限公司 Paris polyphylla fermentation stock solution and preparation method and application thereof
CN110368348A (en) * 2019-08-29 2019-10-25 广州重生化妆品实业有限公司 A kind of formula of acne removal stock liquid and preparation method thereof
CN111514059A (en) * 2020-05-26 2020-08-11 佛山市谷邦生物科技有限公司 Ceramide compound skin-soothing moisturizing factor and facial mask thereof
CN113368019A (en) * 2021-04-28 2021-09-10 东莞美态生物科技有限公司 Dendrobium officinale fermentation liquor, dendrobium officinale essence, preparation method and application

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