CN108186426B - Antibacterial mask liquid, mask and preparation method of mask liquid - Google Patents
Antibacterial mask liquid, mask and preparation method of mask liquid Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention relates to the field of beauty cosmetics, in particular to an antibacterial mask liquid, a mask and a preparation method thereof. The bacteriostatic mask liquid at least comprises the following components in parts by weight: 20-35 parts of deionized water, 65-80 parts of arborvitae water, 0.005-0.02 part of arborvitae essential oil, 4-7 parts of humectant and 0.5-3 parts of auxiliary agent.
Description
Technical Field
The invention relates to the field of beauty cosmetics, in particular to an antibacterial mask liquid, a mask and a preparation method thereof.
Background
The facial mask is a carrier of skin caring product, and is applied on face for 15-30 min, and removed when nutrient of the product is slowly absorbed by skin. Many beauty masks for women are available in the market, but the facial masks contain some chemical substances and have stimulation effect on sensitive skin, so that the facial masks cannot play a role in smoothing the skin after being used, and bacteria are bred due to too many nutritional ingredients of the facial masks; aiming at the problems that the grease on the face of young men and young women in the adolescence is excessively secreted, the face is irritated by powder pricks, the acne is broken by squeezing and is also blood and easy to infect, and the functions of diminishing inflammation and inhibiting bacteria cannot be achieved after the common beauty mask is used.
Aiming at the problems, the invention provides the antibacterial mask liquid, which has the advantages that the main active ingredient is a natural plant extract, the skin is not stimulated, and the effects of whitening, moisturizing, diminishing inflammation, inhibiting bacteria and the like are achieved.
Disclosure of Invention
In order to solve the technical problems, the first aspect of the invention provides an antibacterial mask liquid, which at least comprises the following components in parts by weight: 20-35 parts of deionized water, 65-80 parts of arborvitae water, 0.005-0.02 part of arborvitae essential oil, 4-7 parts of humectant and 0.5-3 parts of auxiliary agent.
As a preferable technical scheme, the antibacterial mask liquid is prepared by the method. The paint at least comprises the following components in parts by weight: 22.2 parts of deionized water, 70 parts of arborvitae water, 0.01 part of arborvitae essential oil, 5.75 parts of humectant and 1.6 parts of auxiliary agent.
As a preferable technical scheme of the invention, the biota orientalis water is obtained by extracting biota orientalis roots serving as raw materials through a water vapor extraction method; the biota orientalis essential oil is obtained by using biota orientalis leaves as raw materials and extracting the raw materials by supercritical carbon dioxide.
As a preferable technical scheme of the invention, the humectant at least comprises the following components in parts by weight: 1-4 parts of methyl propylene glycol, 2-4 parts of glycerol, 0.01-0.12 part of hyaluronic acid, 0.1-2 parts of trehalose and 0.05-0.4 part of allantoin.
As a preferable technical scheme of the invention, the hyaluronic acid is small molecule sodium hyaluronate, and the molecular weight is not higher than 1000000D.
As a preferable technical scheme, the trehalose is one or more of sodium alginate, porphyra polysaccharide, sargassum polysaccharide, undaria pinnatifida polysaccharide, gulfweed polysaccharide, loosestrife polysaccharide, gelidium amansii polysaccharide, eucheuma heterophyllum polysaccharide, hizikia fusiforme polysaccharide, laminarin, spirulina polysaccharide, sargassum horneri polysaccharide, fucans, carrageenin polysaccharide, zostera polysaccharide and chlorella polysaccharide.
According to a preferable technical scheme, the auxiliary agent comprises, by weight, 0.01-0.1 part of a chelating agent, 0.05-0.2 part of a thickening agent, 0.18-0.40 part of a preservative, 0.016-0.03 part of a pH regulator, 0.2-1 part of an emollient, 0.3-0.8 part of a plant soothing agent and 0.01-0.12 part of a solubilizer.
As a preferred technical scheme of the invention, the chelating agent is selected from any one or more of disodium ethylene diamine tetraacetate, caprylyl hydroximic acid, sodium phytate and hydroxyphenylpropionamide benzoic acid; the thickening agent is selected from any one or more of carbomer, xanthan gum, natto gum, cellulose, sodium polyacrylate and polysorbate; the preservative is selected from any one or more of methylparaben, ethylhexyl glycerol and sorbitan caprylate; the pH regulator is 10wt% NaOH solution; the wetting agent is selected from any one or more of bis-PEG-18 methyl ether dimethylsilane, soybean lecithin, propylene glycol, sorbitol, 1, 2-octanediol, p-hydroxyacetophenone and D-panthenol; the plant soothing and sensitizing agent is a commercially available product CalmYang; the solubilizer is selected from one or more of PEG20 hydrogenated castor oil, PEG40 hydrogenated castor oil, PEG60 hydrogenated castor oil and Tween-80.
The second aspect of the invention provides a preparation method of the bacteriostatic mask liquid, which at least comprises the following steps:
adding the moisturizing agent into a preparation pot containing deionized water and arborvitae water according to parts by weight, adding a chelating agent under heating and stirring, stirring at 25Hz until the chelating agent is completely dissolved, and heating to 80 ℃; adding a thickening agent under stirring at 60Hz, adding a preservative after stirring until the thickening agent is completely dissolved, and stirring at 25Hz until the thickening agent is uniform; cooling to 65 ℃, adding a pH regulator, stirring to be uniform at 25Hz, then adding an emollient, and stirring to be uniform at 25 Hz; cooling to 45 ℃, adding the plant sensitivity-improving agent into a preparation pot, and stirring at 25Hz until the plant sensitivity-improving agent is completely dissolved; and cooling to 40 ℃, adding the solubilizer into the preparation pot, uniformly stirring at 25Hz, cooling to room temperature, and filtering with 200-mesh filter cloth to obtain the antibacterial mask liquid.
A third aspect of the present invention provides a mask pack, comprising: the antibacterial facial mask comprises a facial mask matrix used as a carrier and the antibacterial facial mask liquid, wherein the antibacterial facial mask liquid is adsorbed in the facial mask matrix.
The above-described and other features, aspects, and advantages of the present application will become more apparent with reference to the following detailed description.
The main active ingredient of the antibacterial mask liquid is a natural plant extract, so that the antibacterial mask liquid has no stimulation to sensitive skin, and has the effects of moisturizing, diminishing inflammation, inhibiting bacteria and the like.
Detailed Description
The disclosure may be understood more readily by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.
The term "prepared from …" as used herein is synonymous with "comprising". The terms "comprises," "comprising," "includes," "including," "has," "having," "contains," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.
The conjunction "consisting of …" excludes any unspecified elements, steps or components. If used in a claim, the phrase is intended to claim as closed, meaning that it does not contain materials other than those described, except for the conventional impurities associated therewith. When the phrase "consisting of …" appears in a clause of the subject matter of the claims rather than immediately after the subject matter, it defines only the elements described in the clause; other elements are not excluded from the claims as a whole.
When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted to include the ranges "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.
The singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. "optional" or "any" means that the subsequently described event or events may or may not occur, and that the description includes instances where the event occurs and instances where it does not.
Approximating language, as used herein throughout the specification and claims, is intended to modify a quantity, such that the invention is not limited to the specific quantity, but includes portions that are literally received for modification without substantial change in the basic function to which the invention is related. Accordingly, the use of "about" to modify a numerical value means that the invention is not limited to the precise value. In some instances, the approximating language may correspond to the precision of an instrument for measuring the value. In the present description and claims, range limitations may be combined and/or interchanged, including all sub-ranges contained therein if not otherwise stated.
In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.
In order to solve the technical problems, the first aspect of the invention provides an antibacterial mask liquid, which at least comprises the following components in parts by weight: 20-35 parts of deionized water, 65-80 parts of arborvitae water, 0.005-0.02 part of arborvitae essential oil, 4-7 parts of humectant and 0.5-3 parts of auxiliary agent.
As a preferable technical scheme, the antibacterial mask liquid is prepared by the method. The paint at least comprises the following components in parts by weight: 22.2 parts of deionized water, 70 parts of arborvitae water, 0.01 part of arborvitae essential oil, 5.75 parts of humectant and 1.6 parts of auxiliary agent.
Arborvitae
Arborvitae (academic name:Platycladusorientalis(L.) Franco) Belongs to evergreen arbor. The crown is oval, and the branches are flat and arranged into 1 plane. Small leaves, scaly, clinging to small branches, in cross-facing arrangement, and gland groove in the middle of leaf back. Hermaphroditism, unisexual. The pollen of the male ball is yellow and consists of alternate pair of microsporidia, each microsporidia has 3 anthers, and the pearl scale and the bud scale are completely healed. The cones mature in the same year, the scales of the seeds are lignified and cracked, and the seeds do not have wings or have ridges. Arborvitae is a special product in China and is distributed in China except Qinghai and Xinjiang. The service life is very long, and the ancient trees are often hundreds of years and more than hundreds of years. Has been selected as a city tree in Beijing. The arborvitae is drought-enduring, is usually a sunny slope afforestation tree species, is also a common garden greening tree species, can be used as wood for buildings, furniture and the like, has medicinal leaves and branches, and can heal and stop bleeding, promote urination and invigorate stomach, detoxify and dissipate blood stasis; the seed has effects of tranquilizing, nourishing and strengthening.
The Chinese arborvitae has fresh and pleasant smell, and has hemostatic, diuretic and anticancer effects. The Platycladus orientalis extract mainly contains active ingredients such as flavonoids, tannin, essential oil and the like, has the effects of detail bacteriostasis, oxidation resistance and tumor activation resistance, has the effect of stopping bleeding due to the contained quercetin, and has the effect of promoting urination due to the contained myricitrin and quercetin. At present, flavonoids extracted from biota orientalis are applied to the industries of medicine, food, health care, daily chemicals and the like. The current research shows that the arborvitae tops and the water decoction thereof contain five flavonoid compounds of dendrophyllin, isodendrophyllin, dendrophyllin, myricitrin and amentoflavone. The content of tannin in biota orientalis is small, about 2.52%. The activity of tannin in the leaves of platycladus orientalis is not reported at present, but the activity research of tannin separated from other plants is commonly reported, in particular to strong antioxidant activity and good anticancer activity. The arborvitae essential oil has the effects of resisting insects, bacteria, oxidation and cancer, and the like, and has good application prospect in the aspects of development of natural insecticides, preservatives and health care products. The arborvitae oil contains more than 70 compounds, but the main chemical components of the arborvitae leaf oil have larger difference due to differences of regions, seasons, extraction processes, experimental conditions and the like. The arborvitae essential oil comprises the following compounds: 2-carene, limonene, isocitrate, caryophyllene, alpha-pinene, 1-methyl-4-isopropyl-4-hydroxycyclopentene, bicyclo [3.1.0] -decan-2-ol, etc. Research shows that the arborvitae essential oil can inhibit the growth of aerobacter, staphylococcus aureus, escherichia coli and tetragenococcus, and has better inhibition effect on the growth of aspergillus niger, penicillium and rhizopus than the commonly used potassium sorbate as a bacteriostatic agent. The cacumen biotae essential oil also has obvious inhibitory activity on tumor cells NCI-H460.
Chinese arborvitae water
The arborvitae water is arborvitae hydrolat, which is called water essential oil and flower water, and is a 100% saturated distillation stock solution separated during the extraction of essential oil in the distillation extraction process of the essential oil, which is a byproduct of the essential oil, and has natural and pure components and light and pleasant fragrance. The arborvitae water contains small amount of essential oil components, and also contains water soluble components (such as flavone, tannin, flavonoid, lodinic acid, fendorin, cedrol (cedrol, cedrol), cedrene, thujopsirene, longifolene, cedrene, etc.) in whole arborvitae body, and the content of 49 components can be detected deeply. Its low concentration is easy to be absorbed by skin, and has no essence and alcohol component, and is mild and non-irritating. The arborvitae of the present invention is all from Sichuan province.
In a preferred technical scheme of the invention, the biota orientalis water is obtained by extracting biota orientalis roots serving as raw materials through a water vapor extraction method.
As a preferred experimental scheme of the present invention, the method for preparing arborvitae water at least comprises the following steps:
a. cleaning the roots of the Chinese arborvitae, removing impurities such as sandy soil on the surface of the Chinese arborvitae, drying until the water content is lower than 10%, crushing by using a crusher to 10-30 meshes, and filling the crushed Chinese arborvitae into the middle part of a distillation retort;
b. generating 100 ℃ water vapor in a vapor generator, entering from a steam inlet at the lower part of a distillation retort, contacting with a filled raw material of cypress Maki, starting an oil pump after 50s, vacuumizing and generating negative pressure of 40 kPa;
c. after the air pressure is stable, the wood raw materials such as the roots of the cypress 27097are fully contacted with the water by spraying normal-temperature water at the top of the distillation retort for cooling, reducing the pressure and humidifying, so that volatile components such as essential oil in the raw material tissues are extracted and mixed by steam under the condition of less pyrolysis and hydrolysis;
and d.30min later, closing the oil pump, naturally pressurizing to the same atmospheric pressure as the outside, opening a steam pipeline above the distillation tank, and connecting a snake-shaped condenser. Condensing steam, introducing the obtained liquid into a constant-temperature oil-water separator, decolorizing with activated carbon, separating oil phase and water phase, filtering to remove impurities, and collecting water phase as cacumen Platycladi water.
Arborvitae essential oil
Essential oils, chemically known as essential oils, botanically known as essential oils, are commercially known as perfume oils. The liquid is mostly liquid at normal temperature, is volatile, has strong fragrance, can be dissolved in most organic solvents but is not dissolved in water, and contains a large amount of simple compounds with smaller molecular weight. From the plant structure, most of the essential oil exists in oil chambers, oil pipes, secretory cells and resin channels of plants in an oil drop shape. The essential oil is a main secondary metabolite of tissues such as roots, stems, leaves, flowers, fruits, seeds and the like of plants, has different contents and components of the essential oil at different parts, is generally not uniformly distributed in the whole plant, and is a main biological resource.
Many research results show that the plant essential oil has certain insecticidal activity, and compared with a chemical synthetic insecticide, the plant essential oil is difficult to generate drug resistance, has no harm to people and no pollution to the environment, and the like, and has the most obvious advantages of being used as the insecticide. The plant essential oil achieves the insecticidal effect mainly through the action mechanisms of induction, avoidance, food refusal or poison killing and the like. At present, a plurality of plant essential oils are applied to cosmetics and health care products, and the anti-aging effect of the cosmetics and the health care products is improved because the plant essential oils have special fragrance and also because the plant essential oils have good antioxidant activity.
As a preferable technical scheme of the invention, the biota orientalis essential oil is obtained by taking biota orientalis leaves as raw materials and extracting the raw materials by supercritical carbon dioxide.
The platycladus orientalis essential oil is obtained by supercritical carbon dioxide extraction, the extraction temperature is 35-50 ℃, the extraction pressure is 12-20 MPa, the flow is 400-550L/h, the static extraction time is 0-1.5 h, and the static extraction time is 3-5 h.
The platycladus orientalis essential oil is obtained by supercritical carbon dioxide extraction, the extraction temperature is 45 ℃, the extraction pressure is 15MPa, the flow is 500L/h, the static extraction time is 0.5h, and the static extraction time is 3 h.
As a preferable technical scheme of the invention, the humectant at least comprises the following components in parts by weight: 1-4 parts of methyl propylene glycol, 2-4 parts of glycerol, 0.01-0.12 part of hyaluronic acid, 0.1-2 parts of trehalose and 0.05-0.4 part of allantoin.
As a preferable technical scheme of the invention, the humectant at least comprises the following components in parts by weight: 2 parts of methyl propylene glycol, 3 parts of glycerol, 0.03 part of hyaluronic acid, 0.5 part of trehalose and 0.2 part of allantoin.
Methyl propylene glycol
Methyl propylene glycol, CAS: 2163-42-0, abbreviated as MPO, which is a competitive polyol substitute, is derived from plants, has a stronger moisturizing effect than 1, 3-butanediol and propylene glycol, is fresher than glycerin, provides excellent skin feel and moisturizing effect, is almost non-toxic, has no irritation to skin and eyes, and is approved by FDA. Can be used as an essence synergist and a solubilizer and has good antibacterial property.
The methyl propylene glycol of the present invention was purchased from Bisheng commerce, Inc., Guangzhou, brand DUBOIS, model DUB DIOL.
Glycerol, also known as glycerol, CAS: 56-81-5, wherein the glycerol used in the invention is Thailand lotus flower brand glycerol which is purchased from Shanghai vitamin grain chemical Co.
Hyaluronic acid
Hyaluronic Acid (HA), also known as hyaluronic acid and hyaluronic acid, is an unbranched glycosaminoglycan composed of repeating units of D-glucuronic acid and N-acetylglucosamine via β - (1 → 4) and β - (1 → 3) glycosidic linkages, and is widely present in the intercellular space of animal tissues and the tunica interna of some bacteria. The relative molecular mass (Mr) is generally 1X 105～1×107D, the molar ratio of two monosaccharides in the molecule is 1: 1. common methods for HA production include animal tissue extraction and bacterial fermentation. Commercial HA is typically its Sodium salt, Sodium Hyaluronate (SH).
Since HA HAs properties of high molecular mucopolysaccharide such as unique rheological properties, moisture retention, lubricity, thickening property, and the like, and its naturalness, good biocompatibility, and no allergy, HA is widely developed and applied in the fields of cosmetics, health foods, cosmetic surgery, and medicine. In addition, HA HAs physiological activities such as elimination of free radicals and regulation of cell functions, and HAs very important physiological effects in embryonic development, formation of tissues and organs, angiogenesis, wound healing, repair and prevention of skin injury, tumor spread, control of pain and inflammatory response, and the like. HA can bind 1000 times its weight in water. The water retention of HA is positively correlated with the concentration of HA and its Mr, while the permeability to water is negatively correlated with its concentration and its Mr. The HA water solution is smeared on the surface of the skin to form a layer of moisturizing breathable film, so that the skin is smooth and glossy. Compared with other moisturizers, the humectant is characterized in that the influence of the relative humidity of the external environment on the moisturizing effect is small. HA absorbs the highest amount of moisture in a low relative humidity (33%) environment, and absorbs the lowest amount of moisture in a high relative humidity (80%) environment. HA, a unique moisturizing property, is meeting the requirements of skin on the moisturizing effect of cosmetics in the same season and under different environmental humidity conditions, such as autumn and winter and summer.
As a preferable technical scheme of the invention, the hyaluronic acid is small molecule sodium hyaluronate, and the molecular weight is not higher than 1000000D.
The small molecular hyaluronic acid can permeate into dermis, has the effects of slightly expanding capillary vessels, increasing blood circulation, improving intermediate metabolism, promoting skin nutrition absorption, has a strong wrinkle-removing function, can increase skin elasticity, and can delay skin aging.
The small molecule sodium hyaluronate of the present invention was purchased from kyoto.
As a preferable technical scheme, the trehalose is one or more of sodium alginate, porphyra polysaccharide, sargassum polysaccharide, undaria pinnatifida polysaccharide, gulfweed polysaccharide, loosestrife polysaccharide, gelidium amansii polysaccharide, eucheuma heterophyllum polysaccharide, hizikia fusiforme polysaccharide, laminarin, spirulina polysaccharide, sargassum horneri polysaccharide, fucans, carrageenin polysaccharide, zostera polysaccharide and chlorella polysaccharide.
The algal polysaccharide can be obtained by purchasing or preparing according to the existing method.
The seaweed polysaccharide can form hydrogen bonds with water molecules, form an extracellular colloidal matrix containing a large amount of water together with other polysaccharide components and fibrous proteins in the extracellular matrix, and also form a layer of film on the surface of skin to reduce the water evaporation on the surface of the skin, so that the water is dispersed to the stratum corneum from the basal tissue, and the stratum corneum is induced to be further hydrated, thereby preserving the water of the skin and playing a good role in softening the stratum corneum. The algal polysaccharide can also dissolve bacterial outer membrane, thereby promoting the growth of keratinocyte and skin fibroblast, eliminating free radical, maintaining the activity of biochemical substances such as skin growth factor, SOD and the like, effectively preventing skin damage caused by ultraviolet rays and ionizing radiation, and promoting the renewal and repair of damaged skin. The seaweed polysaccharide used in the invention has good effects of moisturizing, inhibiting bacteria and promoting skin repair, and also has good coordination and compounding and synergistic effects with other components.
Allantoin
Allantoin can promote the growth of epithelial cells and influence the rapid granulation of epidermis, can remarkably accelerate wound healing when being used for ulcer and suppurative skin, and is a good skin wound healing agent. Allantoin also maintains skin moisture, moisturizes and conditions non-pathological skin tissue, including dryness, roughness, firmness, deep texture, scaling, wrinkling, aging, keratosis, etc., provides softness, elasticity, and luster to the skin, and prevents chapped skin. In addition, allantoin is a good cutin treating agent, not only can soften cutin, but also can peel off and metabolize cutin, and simultaneously endow sufficient water in intercellular space, so that rough and chapped skin can be smooth and well-prepared.
According to a preferable technical scheme, the auxiliary agent comprises, by weight, 0.01-0.1 part of a chelating agent, 0.05-0.2 part of a thickening agent, 0.18-0.40 part of a preservative, 0.016-0.03 part of a pH regulator, 0.2-1 part of an emollient, 0.3-0.8 part of a plant soothing agent and 0.01-0.12 part of a solubilizer.
As a preferable technical scheme of the invention, the auxiliary agent comprises 0.03 part of chelating agent, 0.12 part of thickening agent, 0.35 part of preservative, 0.024 part of pH regulator, 0.5 part of emollient, 0.5 part of plant soothing agent and 0.05 part of solubilizer in parts by weight.
As a preferred technical scheme of the invention, the chelating agent is selected from any one or more of disodium ethylene diamine tetraacetate, caprylyl hydroximic acid, sodium phytate and hydroxyphenylpropionamide benzoic acid; the thickening agent is selected from any one or more of carbomer, xanthan gum, natto gum, cellulose, sodium polyacrylate and polysorbate; the preservative is selected from any one or more of methylparaben, ethylhexyl glycerol and sorbitan caprylate; the pH regulator is 10wt% NaOH solution; the wetting agent is selected from any one or more of bis-PEG-18 methyl ether dimethylsilane, soybean lecithin, propylene glycol, sorbitol, 1, 2-octanediol, p-hydroxyacetophenone and D-panthenol; the plant soothing and sensitizing agent is a commercially available product CalmYang; the solubilizer is selected from one or more of PEG20 hydrogenated castor oil, PEG40 hydrogenated castor oil, PEG60 hydrogenated castor oil and Tween-80.
According to a preferable technical scheme of the invention, the preservative is a mixture of chlorophenyl glycoside ether and methyl hydroxybenzoate, and the mass ratio of the chlorophenyl glycoside ether to the methyl hydroxybenzoate is 0.6-1: 1.
as a preferable technical scheme of the invention, the preservative is a mixture of chlorophenyl glycoside ether and methyl hydroxybenzoate, and the mass ratio of the chlorophenyl glycoside ether to the methyl hydroxybenzoate is 0.75: 1.
chlorophytidine ester
Chlorphenesin is an excellent preservative, and has the Chinese alias: chlorophenol ether; 3- (4-chlorophenoxy) -1, 2-propanediol. CAS accession number: 104-29-0 English name: 3- (4-Chlorophenoxy) -1, 2-propanoediol. Has wide application in international market, good antiseptic property, high purity, good water solubility, small irritation and low price, and can be used together with phenoxyethanol and other preservatives.
Hydroxy phenyl methyl ester
Methylparaben, also known as Methylparaben, Methylparaben. Methylparaben, CAS: 99-76-3, white crystalline powder or colorless crystals, easily soluble in alcohol, ether and acetone, very slightly soluble in water, boiling point 270-. Molecular formula C8H8O3Molecular weight 152.15. The product is mainly used as a sterilization preservative for organic synthesis, food, cosmetics and medicines, and also used as a feed preservative.
Methyl hydroxybenzoate has broad-spectrum antibacterial activity, can inhibit gram-negative and gram-positive bacteria, has strong inhibiting effect on yeast and mould, and has low use concentration, broad spectrum, high efficiency, safety, economy and long service life compared with traditional antiseptic products (such as sodium benzoate). Can be widely used for the preservation of cosmetics, medicines, foods and other industrial products. The product can be used independently, and can also be compounded with other parabens, thereby achieving better anticorrosion effect. Can be compatible with various components in cosmetics.
The second aspect of the invention provides a preparation method of the bacteriostatic mask liquid, which at least comprises the following steps:
adding the moisturizing agent into a preparation pot containing deionized water and arborvitae water according to parts by weight, adding a chelating agent under heating and stirring, stirring at 25Hz until the chelating agent is completely dissolved, and heating to 80 ℃; adding a thickening agent under stirring at 60Hz, adding a preservative after stirring until the thickening agent is completely dissolved, and stirring at 25Hz until the thickening agent is uniform; cooling to 65 ℃, adding a pH regulator, stirring to be uniform at 25Hz, then adding an emollient, and stirring to be uniform at 25 Hz; cooling to 45 ℃, adding the plant sensitivity-improving agent into a preparation pot, and stirring at 25Hz until the plant sensitivity-improving agent is completely dissolved; and cooling to 40 ℃, adding the solubilizer into the preparation pot, uniformly stirring at 25Hz, cooling to room temperature, and filtering with 200-mesh filter cloth to obtain the antibacterial mask liquid.
A third aspect of the present invention provides a mask pack, comprising: the antibacterial facial mask comprises a facial mask substrate as a carrier and the antibacterial facial mask liquid, wherein the antibacterial facial mask liquid is adsorbed in the facial mask substrate.
The mask matrix is not limited by others, and may be exemplified by crystal gel, plant fiber, biological fiber, silk, charcoal, etc. made of non-woven fabric, pure cotton cloth/fruit and vegetable fiber, silica gel, agar, etc.
The main active ingredient of the antibacterial mask liquid is a natural plant extract, so that the antibacterial mask liquid has no stimulation to sensitive skin, and has the effects of moisturizing, diminishing inflammation, inhibiting bacteria and the like. The invention overcomes the stable compatibility relationship between natural plant extracts and synthetic substances, and provides the optimal proportional relationship, so that the components have good synergistic effect and better anti-inflammatory and antibacterial effects.
The present invention will be specifically described below by way of examples. It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention.
In addition, the raw materials are commercially available and are all used as cosmetic/pharmaceutical grade raw materials unless otherwise specified.
Example 1:
embodiment 1 provides an antibacterial mask liquid, which at least comprises the following components in parts by weight: 20 parts of deionized water, 65 parts of arborvitae water, 0.005 part of arborvitae essential oil, 4 parts of humectant and 0.5 part of auxiliary agent. The humectant at least comprises the following components: 1 part of methyl propylene glycol, 2 parts of glycerol, 0.01 part of hyaluronic acid, 0.1 part of trehalose and 0.05 part of allantoin. The auxiliary agent comprises 0.01 part of chelating agent, 0.05 part of thickening agent, 0.18 part of preservative, 0.016 part of pH regulator, 0.2 part of emollient, 0.3 part of plant soothing agent and 0.01 part of solubilizer. The chelating agent is disodium ethylene diamine tetraacetate; the thickening agent is carbomer 981; the preservative is chlorophenyl glucoside ether; the pH regulator is 10wt% NaOH solution; the wetting agent is bis-PEG-18 methyl ether dimethylsilane; the plant soothing and sensitizing agent is a commercially available product CalmYang; the solubilizer is PEG20 hydrogenated castor oil.
The preparation method of the arborvitae water at least comprises the following steps:
a. cleaning the roots of the Chinese arborvitae, removing impurities such as sandy soil on the surface, drying until the water content is lower than 10%, crushing by a crusher to 30 meshes, and filling the crushed materials into the middle part of a distillation retort;
b. generating 100 ℃ water vapor in a vapor generator, entering from a steam inlet at the lower part of a distillation retort, contacting with a filled raw material of cypress Maki, starting an oil pump after 50s, vacuumizing and generating negative pressure of 40 kPa;
c. after the air pressure is stable, the wood raw materials such as the roots of the cypress 27097are fully contacted with the water by spraying normal-temperature water at the top of the distillation retort for cooling, reducing the pressure and humidifying, so that volatile components such as essential oil in the raw material tissues are extracted and mixed by steam under the condition of less pyrolysis and hydrolysis;
and d.30min later, closing the oil pump, naturally pressurizing to the same atmospheric pressure as the outside, opening a steam pipeline above the distillation tank, and connecting a snake-shaped condenser. Condensing steam, introducing the obtained liquid into a constant-temperature oil-water separator, decolorizing with activated carbon, separating oil phase and water phase, filtering to remove impurities, and collecting water phase as cacumen Platycladi water.
The biota orientalis essential oil is obtained by using biota orientalis leaves as raw materials and performing supercritical carbon dioxide extraction, wherein the extraction temperature is 45 ℃, the extraction pressure is 15MPa, the flow is 500L/h, the static extraction time is 0.5h, and the static extraction time is 3 h.
The preparation method of the bacteriostatic mask liquid at least comprises the following steps:
adding the moisturizing agent into a preparation pot containing deionized water and arborvitae water according to parts by weight, adding a chelating agent under heating and stirring, stirring at 25Hz until the chelating agent is completely dissolved, and heating to 80 ℃; adding a thickening agent under stirring at 60Hz, adding a preservative after stirring until the thickening agent is completely dissolved, and stirring at 25Hz until the thickening agent is uniform; cooling to 65 ℃, adding a pH regulator, stirring to be uniform at 25Hz, then adding an emollient, and stirring to be uniform at 25 Hz; cooling to 45 ℃, adding the plant sensitivity-improving agent into a preparation pot, and stirring at 25Hz until the plant sensitivity-improving agent is completely dissolved; and cooling to 40 ℃, adding the solubilizer into the preparation pot, uniformly stirring at 25Hz, cooling to room temperature, and filtering with 200-mesh filter cloth to obtain the antibacterial mask liquid.
Example 2:
embodiment 2 provides an antibacterial mask liquid, which at least comprises the following components in parts by weight: 35 parts of deionized water, 80 parts of arborvitae water, 0.02 part of arborvitae essential oil, 7 parts of humectant and 3 parts of auxiliary agent. The humectant at least comprises the following components: 4 parts of methyl propylene glycol, 4 parts of glycerol, 0.12 part of hyaluronic acid, 2 parts of trehalose and 0.4 part of allantoin. The auxiliary agent comprises 0.1 part of chelating agent, 0.2 part of thickening agent, 0.40 part of preservative, 0.03 part of pH regulator, 1 part of emollient, 0.8 part of plant soothing agent and 0.12 part of solubilizer. The chelating agent is caprylyl hydroximic acid; the thickening agent is xanthan gum; the preservative is methyl hydroxybenzoate; the pH regulator is 10wt% NaOH solution; the wetting agent is propylene glycol; the plant soothing and sensitizing agent is a commercially available product CalmYang; the solubilizer is PEG40 hydrogenated castor oil.
The preparation method of the arborvitae water is the same as that of the example 1.
The preparation method of the arborvitae essential oil is the same as that of the example 1.
The preparation method of the antibacterial mask liquid is the same as that of the example 1.
Example 3:
embodiment 3 provides an antibacterial mask liquid, which at least comprises the following components in parts by weight: 22.2 parts of deionized water, 70 parts of arborvitae water, 0.01 part of arborvitae essential oil, 5.75 parts of humectant and 1.6 parts of auxiliary agent. The humectant at least comprises the following components: 2 parts of methyl propylene glycol, 3 parts of glycerol, 0.03 part of hyaluronic acid, 0.5 part of trehalose and 0.2 part of allantoin. The auxiliary agent comprises 0.03 part of chelating agent, 0.12 part of thickening agent, 0.35 part of preservative, 0.024 part of pH regulator, 0.5 part of emollient, 0.5 part of plant allergy-relieving agent and 0.05 part of solubilizer. The chelating agent is sodium phytate; the thickening agent is polysorbate; the preservative is ethylhexyl glycerol; the pH regulator is 10wt% NaOH solution; the wetting agent is sorbitol; the plant soothing and sensitizing agent is a commercially available product CalmYang; the solubilizer is PEG60 hydrogenated castor oil.
The preparation method of the arborvitae water is the same as that of the example 1.
The preparation method of the arborvitae essential oil is the same as that of the example 1.
The preparation method of the antibacterial mask liquid is the same as that of the example 1.
Example 4:
embodiment 4 provides an antibacterial mask liquid, which at least comprises the following components in parts by weight: 22.2 parts of deionized water, 70 parts of arborvitae water, 0.01 part of arborvitae essential oil, 5.75 parts of humectant and 1.6 parts of auxiliary agent. The humectant at least comprises the following components: 2 parts of methyl propylene glycol, 3 parts of glycerol, 0.03 part of hyaluronic acid, 0.5 part of trehalose and 0.2 part of allantoin. The auxiliary agent comprises 0.03 part of chelating agent, 0.12 part of thickening agent, 0.35 part of preservative, 0.024 part of pH regulator, 0.5 part of emollient, 0.5 part of plant allergy-relieving agent and 0.05 part of solubilizer. The chelating agent is disodium ethylene diamine tetraacetate; the thickening agent is carbomer 981; the preservative is a mixture of chlorophenyl glycoside ether and methyl hydroxybenzoate, and the mass ratio of the chlorophenyl glycoside ether to the methyl hydroxybenzoate is 0.6: 1. the pH regulator is 10wt% NaOH solution; the wetting agent is bis-PEG-18 methyl ether dimethylsilane; the plant soothing and sensitizing agent is a commercially available product CalmYang; the solubilizer is PEG40 hydrogenated castor oil.
The preparation method of the arborvitae water is the same as that of the example 1.
The preparation method of the arborvitae essential oil is the same as that of the example 1.
The preparation method of the antibacterial mask liquid is the same as that of the example 1.
Example 5:
the specific implementation mode of the embodiment 5 is the same as that of the embodiment 4, except that the preservative is a mixture of chlorophenyl glycoside ether and methyl hydroxybenzoate, and the mass ratio of the chlorophenyl glycoside ether to the methyl hydroxybenzoate is 0.75: 1.
comparative example 1:
the embodiment of comparative example 1 is the same as example 5 except that the thuja water was replaced with deionized water of higher quality.
Comparative example 2:
the embodiment of comparative example 2 is the same as that of example 5 except that the thuja essential oil was replaced with deionized water of higher quality.
Comparative example 3:
the embodiment of comparative example 3 is the same as that of example 5, except that the raw material for preparing the arborvitae essential oil is arborvitae root.
Comparative example 4:
comparative example 4 the same embodiment as example 5, except that the extraction method of the arborvitae essential oil is the same as that of arborvitae water, and the oil phase is arborvitae essential oil. The raw material is cacumen Platycladi.
Comparative example 5:
the embodiment of comparative example 5 is the same as example 5, except that the preservative is a mixture of chlorophenyl glycoside ether and methyl hydroxybenzoate, and the mass ratio of chlorophenyl glycoside ether to methyl hydroxybenzoate is 1.1: 1.
performance evaluation:
1. stability of
a. Placing the antibacterial mask solution in an electric heating constant temperature incubator at 45 +/-2 ℃ for 30 days, and observing the stability of the antibacterial mask solution after the antibacterial mask solution is restored to the room temperature; b. and (3) placing the antibacterial mask liquid in a refrigerator at (-5 +/-2) DEG C for 30 days, and observing the stability of the antibacterial mask liquid after the antibacterial mask liquid is restored to the room temperature. And (3) observing items: and (3) recording the transparency, precipitation, odor change and the like of the bacteriostatic facial mask solution as stable if the bacteriostatic facial mask solution is transparent, free of precipitation and free of odor change, and recording the stable if the bacteriostatic facial mask solution is not transparent, free of precipitation and free of odor change, or recording the unstable if the bacteriostatic facial mask solution is not transparent. The test results are shown in table 1.
Table 1 performance characterization test
2. Skin testing
500 volunteers with the age of 18-50 years and the inflammatory conditions of acne and acne on the face are randomly divided into six groups, and the antibacterial facial masks obtained in the embodiments 1-5 are respectively used. The test method comprises the following steps: taking the facial mask, cleaning the face with clear water, applying the facial mask on the face, taking the facial mask out after 15-20 min, and cleaning the face with clear water; the cosmetic is used once every three days, other cosmetics are not used in the using period, the using time is 30 days, and the testing time of the test is selected to be 2-4 months which are easy to cause the spring allergy phenomenon.
The results of the experiment found that no significant allergic or other irritant reaction occurred in all volunteers during the course of the test, and that over 87% of the volunteers felt significant signs of facial inflammation. The volunteers who used the mask of example 5 felt that facial inflammation was improving at a rate of 100%, and the skin was clearly whiter than before the mask, the acne marks also had signs of lightening, and the skin was moist and glossy.
The foregoing examples are merely illustrative and serve to explain some of the features of the method of the present invention. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. Also, where numerical ranges are used in the claims, subranges therein are included, and variations in these ranges are also to be construed as possible being covered by the appended claims.
Claims (6)
1. The bacteriostatic mask liquid is characterized by at least comprising the following components in parts by weight: 20-35 parts of deionized water, 65-80 parts of arborvitae water, 0.005-0.02 part of arborvitae essential oil, 4-7 parts of humectant and 0.5-3 parts of auxiliary agent;
the arborvitae water is extracted from arborvitae roots by a water vapor extraction method; the biota orientalis essential oil is obtained by extracting biota orientalis leaves serving as a raw material by supercritical carbon dioxide;
the auxiliary agent comprises, by weight, 0.01-0.1 part of a chelating agent, 0.05-0.2 part of a thickening agent, 0.18-0.40 part of a preservative, 0.016-0.03 part of a pH regulator, 0.2-1 part of an emollient, 0.3-0.8 part of a plant soothing agent and 0.01-0.12 part of a solubilizer;
the chelating agent is any one or more of disodium ethylenediamine tetraacetate, caprylyl hydroximic acid, sodium phytate and hydroxyphenylpropionamide benzoic acid; the thickening agent is selected from any one or more of carbomer, xanthan gum, natto gum, cellulose, sodium polyacrylate and polysorbate; the pH regulator is 10wt% NaOH solution; the emollient is selected from any one or more of bis-PEG-18 methyl ether dimethylsilane, soybean lecithin, propylene glycol, sorbitol, 1, 2-octanediol, p-hydroxyacetophenone and D-panthenol; the plant soothing and sensitizing agent is a commercially available product CalmYang; the solubilizer is selected from any one or more of PEG-20 hydrogenated castor oil, PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil and Tween-80;
the preservative is a mixture of chlorophenyl glycoside ether and methyl hydroxybenzoate, and the mass ratio of the chlorophenyl glycoside ether to the methyl hydroxybenzoate is (0.6-1): 1.
2. the bacteriostatic mask liquid according to claim 1, which at least comprises the following components in parts by weight: 22.2 parts of deionized water, 70 parts of arborvitae water, 0.01 part of arborvitae essential oil, 5.75 parts of humectant and 1.6 parts of auxiliary agent.
3. The bacteriostatic mask liquid according to claim 1, wherein the humectant at least comprises the following components in parts by weight: 1-4 parts of methyl propylene glycol, 2-4 parts of glycerol, 0.01-0.12 part of hyaluronic acid, 0.1-2 parts of algal polysaccharide and 0.05-0.4 part of allantoin.
4. The bacteriostatic mask solution according to claim 3, wherein the hyaluronic acid is a small-molecule sodium hyaluronate with a molecular weight of not more than 1000000D.
5. The bacteriostatic mask solution according to claim 3, wherein the algal polysaccharides are one or more of sodium alginate, porphyra polysaccharide, sargassum polysaccharide, undaria pinnatifida polysaccharide, gulfweed polysaccharide, loosestrife polysaccharide, gelidium amansii polysaccharide, eucheuma spinosum polysaccharide, sargassum fusiforme polysaccharide, laminarin, spirulina polysaccharide, sargassum horneri polysaccharide, fucans, carrageenin, zostera polysaccharide and chlorella polysaccharide.
6. A mask pack, comprising: a mask substrate used as a carrier and the bacteriostatic mask liquid according to any one of claims 1-5, wherein the bacteriostatic mask liquid is absorbed in the mask substrate.
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| WO2020258205A1 (en) * | 2019-06-28 | 2020-12-30 | L'oreal | Cosmetic composition for making up and/or caring for keratin materials |
| CN110639334A (en) * | 2019-08-22 | 2020-01-03 | 苏州市易柯露环保科技有限公司 | Plant deodorant for removing dimensionless industrial odor |
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| CN101669892A (en) * | 2009-09-28 | 2010-03-17 | 中山大学 | Arborvitae mask and preparation method thereof |
| CN102925291A (en) * | 2012-11-22 | 2013-02-13 | 广西森呼吸科技工程有限公司 | Variable pressure distillation method for extracting pythoncidere and essential oil from Chamaecyparis plants |
| CN102920639A (en) * | 2012-11-22 | 2013-02-13 | 广西森呼吸科技工程有限公司 | Whitening and firming face mask containing plant extractives and preparation method of whitening and firming face mask |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101669892A (en) * | 2009-09-28 | 2010-03-17 | 中山大学 | Arborvitae mask and preparation method thereof |
| CN102925291A (en) * | 2012-11-22 | 2013-02-13 | 广西森呼吸科技工程有限公司 | Variable pressure distillation method for extracting pythoncidere and essential oil from Chamaecyparis plants |
| CN102920639A (en) * | 2012-11-22 | 2013-02-13 | 广西森呼吸科技工程有限公司 | Whitening and firming face mask containing plant extractives and preparation method of whitening and firming face mask |
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