KR20150116504A - A cosmetics composition containing tea tree and solt - Google Patents

A cosmetics composition containing tea tree and solt Download PDF

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KR20150116504A
KR20150116504A KR1020140041090A KR20140041090A KR20150116504A KR 20150116504 A KR20150116504 A KR 20150116504A KR 1020140041090 A KR1020140041090 A KR 1020140041090A KR 20140041090 A KR20140041090 A KR 20140041090A KR 20150116504 A KR20150116504 A KR 20150116504A
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tea tree
salt
skin
extract
present
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최승호
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(주) 에이치에스디
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

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Abstract

The present invention relates to a cosmetic composition containing a Tea Tree extract and salt. The composition containing the Tea Tree extract and salt provides moisturizing effects in accordance with increase in a content of hyaluronic acid (HA), and also improves pulling phenomenon of skin, roughness, and loss of firmness through inhibition of hyaluronidase (HYAL) and production of HA in hyaluronic acid synthase (HaCaT). To this end, all toxic substances in salt are eliminated by heating natural salt at higher than or equal to 800°C for seven to eight hours, and the heated natural salt contains inorganic components and minerals, thereby providing excellent effects of moisturizing and reproduction of skin. Moreover, the present invention provides a composition containing a Tea Tree extract and salt, which can enhance efficacy thereof, if using the composition along with the Tea Tree extract of the present invention.

Description

The present invention relates to a cosmetic composition containing tea tree extract and salt,

The present invention relates to a cosmetic composition comprising tea tree extract and salt. More particularly, the present invention relates to a cosmetic composition comprising tea tree extract and salt, To a cosmetic composition comprising tea tree extract and salt which improves skin pulling, roughness, lack of elasticity, and the like.

The skin is largely divided into three layers: epidermis, dermis, and subcutaneous tissue in order from the outside. It has a function to protect the internal organs of the body from changes in temperature and humidity, ultraviolet rays, and other physical and chemical external stimuli.

Skin aging is caused by oxidative damage of intracellular substances by free radicals. That is, highly reactive free radicals, such as active radicals such as hydroxy radicals and superoxide radicals, oxidize the lipid components constituting the cell membrane to destroy the cell membrane, thereby oxidizing the protein and stopping the function of the nucleic acid, It destroys its components and causes cell death. Such skin aging can be caused by excessive exposure to ultraviolet rays, nutritional deficiency of skin cells, and side effects of cosmetics.

The major cause of skin cell nutritional deficiency is the inadequate nutrition of skin cells due to unbalanced nutrition such as excessive diet and irregular diet. As a result, the production of collagen in the dermal layer is inhibited and the moisture of the skin is evaporated Symptoms appear, and it also causes abnormalities in the subcutaneous fat layer, causing loss of skin elasticity.

In particular, the epidermis plays an important role in preventing water evaporation inside the human body. The epidermis is divided into stratum corneum, granular layer, superficial layer, and basal layer in order from the outside. Cells of stratum corneum act like bricks, and intercellular lipids between keratinocytes act like mortar to constitute skin barrier. In addition, a healthy human keratinocyte has a high concentration of natural moisturizing factor (NMF) to help maintain moisture in the skin. For example, substances such as amino acids are water-soluble, Thereby suppressing drying.

In addition, as the ozone layer is destroyed due to excessive environmental pollution, the particles in the ultraviolet rays form negative ions and combine with the protein molecules constituting the skin cells to generate free radicals. This is an unstable substance, And the protein of the skin cell is converted into another protein, thereby greatly damaging the skin cell. The damaged skin cell becomes unable to function as its own cell, and the skin cell becomes aged.

In addition, the side effects of cosmetics to break the harmony of fat and moisture in the skin causes skin aging. Therefore, it is possible to prevent or reduce skin aging by inhibiting oxidative damage in vivo. Antioxidant cosmetics, on the other hand, inhibit the oxidative damage of skin, including the oxidation of fat components, to prevent or delay skin aging.

However, as it is nowadays, there is a tendency to adjust the temperature of the air / heating due to the change of environment or life pattern, the stress caused by various stresses and environmental pollution in the social life, frequent washing according to make- Due to various causes such as aging of skin and the like, moisture of the stratum corneum is reduced, and the skin becomes dry, the surface becomes rough, the skin becomes loose, the luster is lost and the skin looks dull, and the need for skin moisturizing agent is increasing.

Quercetin, alpha-tocopherol, ascorbic acid, beta-carotene, hydroquinone and the like have been known to have antioxidative action so far . However, most of these substances are chemically synthesized. These chemicals are limited or limited in use due to safety concerns. If these toxic substances are continuously accumulated in the body, they may cause chronic toxicity, carcinogenicity, mutagenicity And so forth.

Maintaining a constant water content in the skin implies that it constitutes a barrier to avoid water loss, considering that water molecules evaporate.

Several kinds of lipids, sugars, and proteins are involved and interact in order for these barriers to work smoothly. According to the structural formula of hyaluronic acid (HA), double hyaluronic acid (HA) is known to be a glycosaminoglycan of a polymer present in extracellular connective tissues and acts as a barrier against moisture evaporation. It was reported to be reduced.

Long-term exposure to UV radiation, especially from external environmental factors, has a negative impact on the maintenance of a constant HA of the skin. The decrease in HA content due to these intrinsic or extrinsic factors is a factor of skin elasticity reduction, rough skin and wrinkles. Therefore, maintaining the HA content in the skin is very important for keeping skin moisturized as well as young skin for cosmetics.

The content of HA is controlled by the synthesis by continuous hyaluronic acid synthase (HAS) and the degradation by hyaluronidase (HYAL). One method of maintaining or increasing HA content in the skin is to increase the synthesis of HA while at the same time inhibiting HA degradation.

Therefore, it has been confirmed that the combination of a medicinal substance capable of increasing hyaluronic acid synthase (HAS) gene expression and a decrease in hyaluronidase (HYAL) activity or a medicinal substance having these two functions can be a method for enhancing the moisturizing power of the skin Respectively. Indeed, many natural products and substances have been reported to increase the production of HA through increased gene expression of HAS, including black rice, compound K, kaempferol, quercetin and retinoic acid isolated from ginseng.

Therefore, the present inventors confirmed the moisturizing effect in the skin moisture content measurement test through the composition of the cosmetic composition containing the tea tree leaf extract and the active ingredient of the salt, and confirmed the effect of the humankeratinocyte HaCaT on HA production and HYAL inhibition And completed the present invention.

[Related Technical Literature]

1. Cosmetic composition for skin miosture (Patent Application No. 10-2004-0083125)

2. Composition for skin external application comprising Astragalus Membranaceus extract prepared by using pottery extract (Patent Application No. 10-2007-0123388) containing an extract of Angelica keiskei koidz

3. Cosmetic composition containing extract of Astragalus containing a large amount of astragaloside (Patent Application No. 10-2009-0116784)

The object of the present invention is to solve the above-mentioned problems, and it is an object of the present invention to provide a composition containing tea tree extract and salt, which is a mechanism of moisturizing effect by increasing HA content, And to provide a cosmetic composition comprising tea tree extract and salt which improves pulling, roughness and lack of elasticity.

According to an aspect of the present invention to achieve the above object, the present invention provides a method for producing a hyaluronic acid synthase (HaCaT) cell, which is an active ingredient of tea tree leaf extract and salt, And a cosmetic composition comprising the tea tree leaf extract and the salt.

In addition, the cosmetic composition comprising tea tree leaf extract and salt according to an embodiment of the present invention is characterized in that the tea tree leaf part is an extract obtained by using n-hexane, CHCl 3 or EtOAc solvent and a fraction obtained by sequentially extracting it with a solvent And a control unit.

In addition, the cosmetic composition comprising tea tree leaf extract and salt according to an embodiment of the present invention is characterized in that the tea tree leaf extract contains 0.1 to 10% by weight based on the total weight of the composition as an active ingredient, 8% (Skin), a convergent lotion, a nutritional lotion (lotion), a nutritional cream, a massage cream, a cleanser or an essence.

The tea tree extract and the cosmetic composition containing the salt according to the present invention are characterized by a composition containing tea tree extract and salt as a mechanism of moisturizing effect by increasing the content of HA, and by HA production and HYAL inhibition in HaCaT, , The elasticity shortage phenomenon can be improved.

In addition, the cosmetic composition comprising the tea tree extract and the salt of the present invention is prepared by heating the natural salt at a high temperature of 800 ° C or higher for 7 to 8 hours to remove all harmful substances of the salt, and the heated natural salt contains the mineral component and the mineral component Can exert an effect of moisturizing the skin and regenerating the skin, and when used together with the tea tree extract of the present invention, the effect of improving the efficacy can be obtained.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a view showing a process for producing each fraction of a tea tree leaf part of the present invention
2 is a graph showing the results of measurement of the water loss rate according to the use of the tea tree extract of the present invention and the cream containing the salt
FIG. 3 is a graph showing the results of measurement of the water retention rate of the skin when the cosmetic composition containing the tea tree extract and the salt according to the embodiment of the present invention is applied to human body

Hereinafter, the tea tree extract and the cosmetic composition containing the salt according to a preferred embodiment of the present invention will be described in detail.

The detailed description will be made with reference to the accompanying drawings. In the following description of the present invention, detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear.

The characteristics and efficacy of the tea tree and salt, which are the raw materials of the cosmetic composition of the present invention, will be briefly described below.

Tea tree belongs to Leptospermum, Melaleuca, Kunzea. About 86 species are known to Leptospermum genus and about 230 species are found in Melaleuca.

Origin is native to Australia and New South Wales. It grows in a marshy area up to about 6m in height. It grows well even if it cuts its stem because its vitality is strong. It is a kind of hub that plays a role of refreshing air.

Aboriginal Australians have long been treating infections caused by cuts of leaf tea tree leaves. During the Second World War, it was paid to soldiers in the tropics as a treatment for skin wounds. It is used in surgery and dentistry. It is also used in disinfectant disinfectant, deodorant, soap, air purifier. It is also effective in various infectious diseases, cold, bad breath, athlete's foot, dandruff. However, since it is highly irritant, it is recommended to dilute the stock solution.

Because Tea Tree is highly irritant, it dilutes 2% of carrier liquid such as almond, apricot, and hazelnut, and is the most powerful immunostimulant with antibacterial and antiviral antifungal effect. It activates leukocyte, It is a substance that is used for respiratory and urinary tract infections by constructing a defense line, shortening the period of illness and antibacterial action on the respiratory system and urinary tract.

When tea tree oil is exposed to sunlight, the trace amount of paracimen is rapidly increased from 3% to 305d, and terpinene-4-ol, which has an antimicrobial effect, is oxidized and converted to trihydroxydentimene. Para-cymene has been shown to cause painful erythema and edema on the skin, and oxidized tea tree oil, when applied to the skin, not only delays the treatment of the symptoms but also causes chemical burns, Must be kept.

Staphylococcus aureus (CH Chan et al., 1998, Christine F. Carson et al., 2002) was also used in this study. Klebsiella pneumoniae (Katherine A. Hammer et al., 2004), Candida albicans (SD Cox et al., 2000), Pseudomonas aeruginosa (S. Messager et al., 2005; Katgerine A. Hammer et al., 1996), Serratia marcescens, (Tong MM et al., 1992; Andrew C. Satchell et al., 2002)), the tea tree oil has been reported to be effective against onychomycosis (Buck DS et al, , acne (Bassett IB et al, 1990), and dandruff (Satchell AC et al, 2002).

In particular, the antimicrobial activity against Trichophyton rubrum, a dermatophytic strain, was reported not only by the antimicrobial activity using a plate medium (Steven Benger et al, 2004) but also by the vapour contact (S. Inouye et al, 2001).

Tea Tree is a plant natural antimicrobial oil that has been used as a cosmetic and medicinal product because it has been used as an extract of leaves for skin diseases and has excellent antimicrobial action.

In addition, the osmotic action of salt effectively removes dead skin as well as dead skin, promoting metabolism and helping blood circulation. It also has a sterilization and anti-inflammatory effect, which not only helps alleviate rashes such as acne and rash, but also gives moisture to the skin and gives it an excellent moisturizing effect. If you eat a lot of harmful to your body is not known to be a refined salt, such as bamboo salt and Dead Sea salt minerals rich and fine salt should be used to select. It is also a good idea to use fine-grained sun-dried salt.

Therefore, if the natural salt is heated at a high temperature of 800 ° C or more for 7 to 8 hours, all the harmful substances in the salt are removed, and the heated natural salt is excellent in the moisturizing effect of the skin and the regeneration of the skin, , And when it is used together with the tea tree extract of the present invention, the effect of improving the efficacy can be obtained.

The present invention is to provide a moisturizing cosmetic composition containing 8% of natural salt of sun salted salt and tea tree extract.

In the present invention, tea tree extract can be used as an active ingredient of a cosmetic composition, and can be preferably used as a cosmetic composition. The tea tree composition contains 0.1% to 10% by weight of tea tree extract.

The tea tree extract of the present invention was classified into tea tree leaves and classified into a sample which was refluxed and extracted with 95% ethyl alcohol at room temperature for 2 hours and a sample which was refluxed twice at 50 ° C for 2 hours, followed by filtration and concentration under reduced pressure .

 The tea tree extract thus obtained is highly effective in cosmetic compositions because of its high antibacterial activity against the hyaluronic aid synthase (HaCaT) for moisturizing. Accordingly, the present invention relates to a tea tree extract and a cosmetic composition containing salt which are effective for moisturizing and skin improvement.

 The content of tea tree extract contained in the cosmetic composition is preferably from 0.1% to 10% by weight, more preferably from 0.1 to 5% by weight. When the content is less than 0.1% by weight, the antibacterial effect is insignificant. When the content is more than 10% by weight, there is a problem that the effect according to the usage amount is lowered.

 The above-mentioned cosmetic composition can be blended with usual ingredients to be blended with common skin cosmetic ingredients such as oil, water, surfactant, humectant, lower alcohol, thickening agent, chelating agent, coloring matter, perfume and the like as necessary.

The cosmetic composition is used for the skin, and can be used for skin, cosmetic lotion, nutritional lotion, nutritional cream, massage cream, essence, pack, skin patch, skin adhesive gel, powder, soap, Suspension, emulsion, spray or cosmetics, and the like.

Hereinafter, preferred embodiments of the present invention will be described in order to facilitate understanding of the present invention.

FIG. 1 is a view showing a process for producing the respective fractions of the tea tree leaf part of the present invention, and FIG. 2 is a graph showing the results of measurement of the water loss rate according to the use of the tea tree extract of the present invention and the cream containing the salt FIG. 3 is a graph showing the results of measurement of the moisture retention rate of skin when the cosmetic composition comprising tea tree extract and salt according to an embodiment of the present invention is applied to the human body over time.

However, the following examples are provided only for the purpose of easier understanding of the present invention, and the present invention is not limited to the following examples.

Example 1.

1. Tea tree extract preparation

Tea tree leaves were dried and pulverized, and 100 g of tea tree was extracted with 80% (v / v) methanol and ethanol using room temperature extraction method and hot extraction method to prepare four kinds of extracts as shown in Table 1.

For extraction at room temperature, the sample was immersed twice in a solvent for 72 hours, filtered and concentrated. The warm-up extraction was performed by extracting the sample twice at 50 ° C for 2 hours, filtering, and then concentrating

Hyaluronic aid synthase (HaCaT) cells were treated with 10% fetal bovineserum (FBS, Gibco) and 1% penicillin-streptomycin (PS, Gibco) in Dulbecco's Modified EagleMedium (DMEM, Gibco) to determine the moisturizing effect of each extracted tea tree extract. Were cultured in a medium containing 5% CO 2 at 37 ° C to observe the antimicrobial activity.

The antimicrobial activity for this study is shown in Tables 1 and 2.

Extraction conditions of tea tree leaf extract extract part Solvent conditions Temperature condition One

leaf
Methanol
Room temperature
2 Warming 3 Ethanol in alcohol
Room temperature
4 Warming

Antibacterial activity of tea tree leaf extract Antibacterial activity of tea tree extract (0.9%) extract

Leaf part
Antimicrobial activity
One ++ 2 ++ 3 +++ 4 +

-: Does not inhibit growth of bacteria

+: grow to over 100 colony

++: colony 1 - Grow 100

+++: 100% inhibition of colony growth

Example 2.

Determination of minimum inhibitory concentration (MIC) of tea tree extract

In order to measure the anti-inflammatory effects of the first and third anti-inflammatory activities of the tea tree extract obtained in Example 1, the cells were inoculated in a culture medium of Hyaluronic aid synthase (HaCaT) to a final bacterial concentration of 10 5 CFU / ml .

After incubation at 32 ° C for 48 hours, microbial growth and non-growth of microorganisms were observed by microdilution method and the minimum inhibitory concentration (MIC) And the results are shown in Table 3 below.

Antibacterial activity according to concentration of tea tree leaf extract Antibacterial activity of tea tree leaf fraction extract Concentration (1%) cell

Tea tree leaf extract
0.1 -
0.3 ++ 0.5 +++ 0.9 ++

-: Does not inhibit growth of bacteria

+: grow to over 100 colony

++: colony 1 - Grow 100

+++: 100% inhibition of colony growth

As a result of the above Table 3, it was confirmed that the MIC for the hyaluronic aid synthase (HaCaT) of the tea tree leaf extract was 0.5%, respectively.

It can be seen that when the 0.5% extract of the tea tree leaf part of Table 3 is administered, the active bacteria growth is inhibited by 100%.

Example 3.

Fractionation and antibacterial activity of tea tree leaf

Fractions 3 were sequentially extracted from the tea tree extracts obtained in Example 1 and Example 2, respectively, into n-hexane, CHCl 3 , EtOAc and residues.

That is, as shown in FIG. 1, the tea tree leaf part of the present invention was prepared by extracting leaves with a solvent at room temperature, and then the extract was dissolved in each solvent n-hexane (1-1), CHCl 3 (1-2), EtOAc (1-3) and Residue (1-4).

In order to measure the anti-inflammatory activity of each tea tree leaf part of the thus-extracted extract, the seeds were inoculated to a hyaluronic aid synthase (HaCaT) medium to have a final bacterial concentration of 10 5 CFU / ml. Each of the inoculated strains was treated with 0.9% of each fraction and cultured at 32 ° C for 48 hours. The growth and non - growth of the bacteria were visually observed.

The details of the present invention are shown in Table 4.

Antibacterial activity of tea tree leaf fraction; Antimicrobial activity of tea tree leaf fraction (0.9%) extract Fraction Antimicrobial activity n-hexane fraction 1-1 - Tea tree leaf HCl3 fraction 1-2 ++ The tOAc fraction 1-3 +++ esidue 1-4 -

-: Does not inhibit growth of bacteria

+: grow to over 100 colony

++: colony 1 - Grow 100

+++: 100% inhibition of colony growth

The above tea tree leaf extract has antimicrobial activity against the hyaluronic aid synthase (HaCaT) medium.

The tea tree extract and the cosmetic composition containing the salt according to the present invention can be suitably used for the purpose or use of the moisturizing cream, the skin lotion, the gel, the foam, the powder, the body wash, the scrub shampoo, It can be used for a variety of purposes such as cleansing, bathing, hair removal, and skin massage.

Example 4. Cosmetic composition for skin moisturizer

Tea Tree Extract and Salt Composition Ratio ingredient Content (% by weight) Purified water 66.39 (5% by weight of glycerin + 1% by weight of phage) 6 Surfactants 14.01 antiseptic 0.1 Incrementer 0.7 Spices 0.8 Roasted salt 8 Tea tree extract 10

The purified water, moisturizing agent, surfactant, preservative, thickener, fragrance, baked salt and tea tree extract were respectively weighed according to the composition shown in the above Table 5, and classified into a water phase component, an oil phase component and an additive component, And then the aqueous phase component and the water phase component were stirred at 25 ° C. for 10 minutes while maintaining 78 ° C. at 2500 rpm using a mixing machine. Then, the components were added at 55 ° C. and stirred for about 5 minutes, and then cooled to 40 ° C. A tree extract and a salt were prepared.

Hereinafter, the skin-moisturizing cosmetic according to the above composition was subjected to a skin irritation test and an evaluation of moisturizing ability, and the results were tabulated.

The moisturizing cream cream prepared by the above method was applied to 50 adult men and women as water of hot water, and then stimulated after 3 minutes. The second experiment was stimulated 30 minutes later. The stimulation test was performed 10 days later and the fourth test was conducted every morning and two times 30 days after the evening.

Reaction criteria for skin irritation test reaction Reaction value Reaction criterion 0 0.0 No reaction + 0.5 Faint erythema ++ 1.0 Weak erythema +++ 2.0 Pronounced erythema ++++ 3.0 channel

* Skin response calculation formula = response value X response person number

* Average Reaction Rate = (First Reaction Value x Reaction Number + Second Reaction Value x Reaction Number + Third Reaction Value x Reaction Number + Fourth Reaction Value x Reaction Number) The criteria for the average response were calculated and the degree of stimulation was shown according to the criteria in Table 8.

Based on the average response of the irritant response, Skin mean response Criteria 0 to 0.49 No stimulation 0.5-0.99 Light stimulus 1.0-1.99 Moderate irritation 2.0 to 3 River stimulation

Reactivity (irritant skin reaction) reaction Reaction value Number of first experiment responders Number of second experiment responders Number of respondents in the third experiment Number of respondents Average reactivity 0 0.0 50 people 50 people 45 people 40 people 0 + 0.5 0 0 One One 0.006 ++ 1.0 0 0 0 0 0 +++ 2.0 0 0 0 0 0 ++++ 3.0 0 0 0 0 0

The results of the responses according to the average judgment criteria in Table 7 (Table 8) indicate that skin irritation was caused by the average response value of 0.006 or less.

<Moisture power evaluation>

The moisturizing power of the tea tree extract and the moisturizing cosmetic composition containing the salt according to the present invention was evaluated as follows. Here, the moisturizing power means the moisture holding amount of the stratum corneum.

Each sample was applied to a 5 cm x 5 cm area inside the subject's arm, rubbed for 1 minute, and then rinsed for about 10 seconds in flowing water about 30 seconds later. The water content was measured twice after being carried out at intervals of 4 hours per day, and the results are shown in Table 9 and FIG. 2 below. The test was carried out at 15, 30, 60, and 120 minutes in a constant temperature and humidity chamber at 25 ° C and a relative humidity of 50%, using a Corneometer CM 825 (Courage + Khazaka, Germany).

Herein, the control group of the cosmetic composition according to the present invention was washed with water flowing in a region of 5 cm x 5 cm inside the arm of the subject for about 10 seconds, and moisture content was measured.

Moisture power evaluation result table division 0 minutes 15 minutes 30 minutes later 60 minutes 120 minutes Control group 0 0.77 0.52 0.76 1.27 Experimental group (Example) 0 -15.63 -18.81 -15.09 -13.74

As shown in Table 9, FIG. 2 and FIG. 3, it can be seen that the tea tree extract according to the present invention and the cosmetic composition containing the salt have a much higher moisture retention than the control group.

Hereinafter, the formulation of the present invention is exemplified by a softening longevity (skin), a nutritional lotion (lotion), an essence, a nutritive cream, a massage cream, a pack, a sensitizer (cleansing foam) The formulations that comprise are not so limited.

Brother 1. Flexible lotion (skin)

To prepare a skin lotion for skin comprising the tea tree extract of the present invention and salt, it may be formulated as described in Table 10 below and may be manufactured according to a conventional manufacturing method in the field of cosmetics.

Mixed proportion of soft lotion ingredient Content (% by weight) Tea tree extract 0.1 to 10% Roasted salt 8.0% 1,3-butylene glycol 3.0 glycerin 5.0 Polyoxyethylene (60) Hardened castor oil 0.2 ethanol 8.0 Citric acid 0.02 Sodium citrate 0.06 antiseptic a very small amount Spices a very small amount Purified water To 100

Formulation Example 2. Nourishing lotion (lotion)

To prepare a skin lotion for skin comprising the tea tree extract of the present invention and salt, it may be formulated as described in Table 11 below and may be manufactured according to a conventional manufacturing method in the field of cosmetics.

Nutrition lotion mixing ratio ingredient Content (% by weight) Tea tree extract 0.1 to 10% Roasted salt 0 % 1,3-butylene glycol 8.0 glycerin 5.0 Squalane 10.0 Monooleic acid polyoxyethylene sorbitan (6E.0) 2.0 Triethanolamine 1.5 Glyceryl stearate 0.5 Stearyl glycyrrhetinate 0.2 Carboxyvinyl polymer 0.1 Arginine 0.1 antiseptic a very small amount Spices a very small amount Purified water To 100

Formulation Example 3. Essence

To prepare essences for skin comprising the tea tree extract of the present invention and salt, as described in Table 12 below, they can be manufactured according to a conventional manufacturing method in the field of cosmetics.

Essence combination ratio ingredient Content (% by weight) Tea tree extract 0.1 to 10% Roasted salt 8.0% Sitosterol 1.7 The polyglyceryl 2-oleate 1.5 Ceramide 0.7 Setares-4 1.2 cholesterol 1.5 Dicetyl phosphate 0.4 Concentrated glycerin 5.0 Carboxyvinyl polymer 0.2 Xanthan gum 0.2 antiseptic a very small amount Spices a very small amount Purified water To 100

Formulation Example 4. Cleanser (cleansing foam)

To prepare a skin cleanser (cleansing foam) containing the tea tree extract of the present invention and salt, it may be formulated as described in Table 13 below and may be manufactured according to a conventional manufacturing method in the field of cosmetics.

Composition ratio of cleanser ingredient Content (% by weight) Tea tree extract 0.1 to 10% Roasted salt 8.0% Sodium N-acylglutamate 20.0 glycerin 10.0 PEG-400 15.0 Propylene glycol 10.0 POE (15) oleyl alcohol ether 3.0 Laurin derivative 2.0 Methyl paraben 0.2 EDTA-4Na 0.03 Spices 0.2 Purified water To 100

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments. It is not used for. Therefore, those skilled in the art will appreciate that various modifications and equivalent arrangements may be made therein without departing from the scope of the present invention.

Claims (3)

A cosmetic composition comprising tea tree leaf extract and salt, characterized in that skin moisturization is maintained by the production of hyaluronic acid (HA) in hyaluronic aid synthase (HaCaT) cells as an effective ingredient of tea tree leaf extract and salt.
The method according to claim 1,
Wherein the tea tree leaf part comprises an extract obtained by extracting with n-hexane, CHCl 3 or EtOAc solvent and a fraction obtained by sequentially extracting it with a solvent.
3. The method according to any one of claims 1 to 3,
Wherein the tea tree leaf extract contains 0.1 to 10% by weight based on the total weight of the composition as an active ingredient and contains baked salt in an amount of 8% by weight and contains softening longevity (skin), convergent lotion, nutritional lotion (lotion) A cosmetic composition comprising a tea tree leaf extract and a salt, wherein the tea tree leaf extract is a mixture of a cream, a cleanser and an essence.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190027641A (en) 2017-09-07 2019-03-15 주식회사 래디안 Natural antibacterial agent and manufacturing method thereof
KR102342695B1 (en) 2021-07-14 2021-12-24 에이드코리아컴퍼니 주식회사 Cosmetic composition for skin soothing

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190027641A (en) 2017-09-07 2019-03-15 주식회사 래디안 Natural antibacterial agent and manufacturing method thereof
KR102342695B1 (en) 2021-07-14 2021-12-24 에이드코리아컴퍼니 주식회사 Cosmetic composition for skin soothing

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