CN105362129B - A kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid and preparation method thereof - Google Patents
A kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid and preparation method thereof Download PDFInfo
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- CN105362129B CN105362129B CN201510765111.6A CN201510765111A CN105362129B CN 105362129 B CN105362129 B CN 105362129B CN 201510765111 A CN201510765111 A CN 201510765111A CN 105362129 B CN105362129 B CN 105362129B
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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Abstract
The invention belongs to cosmetic technical field, and in particular to a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid and preparation method thereof.The facial mask liquid containing Folium Artemisiae Argyi extractive liquid of the present invention is mainly made of Folium Artemisiae Argyi extractive liquid, moutan bark extracting solution, hazel extract, compound amino acid, carboxymethyl chitosan, hydroxyethyl cellulose, allantoin, propane diols, pentanediol, glycerine, preservative and water.Facial mask liquid provided by the invention containing Folium Artemisiae Argyi extractive liquid has effects that the bactericidal properties of wide spectrum, antianaphylaxis, anti-inflammatory, soothes the skin fatigue, inoxidizability, promotes cell growth and accelerate wound healing, while also has the function that moisturizing, moisturizing.And this contains the facial mask liquid of Folium Artemisiae Argyi extractive liquid to no skin irritation, long-time service is not in the phenomenon of dermal toxicity, is a kind of healthy, multi-functional facial mask liquid, is adapted to various people to use.
Description
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of containing the facial mask liquid of Folium Artemisiae Argyi extractive liquid and its preparation side
Method.
Background technology
With the development of society and the progress of science and technology, the work of people and life stress are increasing, problem of environmental pollution
Also it is increasingly severe.It is long-term to live in the environment that fast pace, diet are irregular and pollution is larger, cause the skin of people to be resistant to
Ability constantly weakens, and skin sensitivity, impaired situation are increasingly severe, and sub-health state is presented in the skin of more and more people.Cause
This, skin nursing has been increasingly becoming an indispensable part in people's life.
As one of beauty product, it has the advantages of improvement skin effects are notable, easy to use and is consumed deeply facial mask
Person's likes.Facial mask using when be to be covered in the non-woven fabrics mask for being soaked with facial mask liquid face 15-20 minutes, so can be temporary
When face isolate with extraneous air and pollution, improve skin temperature, expand skin pore, promote sweat gland secretion and newly old generation
Thank, the oxygen content of skin is increased, be conducive to skin and exclude the product of epidermal cell metabolism and the oil substances of accumulation,
Facial mask liquid in pad pasting penetrates into the cuticula of skin epidermis, skin is become soft, naturally bright and flexible.
However, the effect of facial mask on the market mainly pays attention to moisturizing, whitening, nti-freckle at present, but these facial masks often can
Substantial amounts of thickener, such as card ripple, triethanolamine, sodium acrylate/sodium acryloyldimethyl taurate copolymers material are added, with
And EDTA chelating agents and the preservative containing Form aldehyde release body, to skin, there are certain irritation, long-time service easily to occur
Inflammation, the phenomenon of allergy.
Plant extracts is to extract to be made from pure natural plant, its alkaloid contained, flavonoids, organic acid and soap
Glycosides isoreactivity material has sterilization, anti-inflammatory, antipruritic effect, and is free from side effects.Therefore, the facial mask containing plant extracts
Liquid is increasingly favored be subject to people seeking beauty.
Chinese patent application 201210451965.3 discloses a kind of anti-inflammatory facial mask liquid, and the facial mask liquid is by green tea powder, third
The raw materials such as triol, cucumber extract, fresh milk and peppermint leaf extract form, and the facial mask liquid being prepared can effectively alleviate skin
Skin inflammation, to no skin irritation, suitable for sensitiveness skin.But the facial mask liquid function is single, wanting for modern is not met
Ask.
Chinese patent application 201510095165.6 discloses a kind of facial mask liquid for promoting skin regeneration antiallergic, the facial mask
Liquid is by hyaluronic acid, Trenaxmine, hesperidin methyl, Sensor Chip CM 5, wheat gluten hydrolyzate, henon bamboo leaf extract, radix scutellariae
Extracting solution, red sage root extracting solution, ginger extract, extract solution from aloe, wild chrysanthemum extracting solution, Rhizoma Atractylodis Macrocephalae extracting solution and 1,2- hexylene glycol
Composition.The facial mask liquid energy being prepared can activate the repair ability of skin itself from endogenous adjusting anti-inflammatory immune system, make
With rear skin comfort, face's erythema can be improved, be adapted to various people to use.But the facial mask liquid contains Trenaxmine, makes for a long time
With easily there is the phenomenon of dermal toxicity, the application of the facial mask liquid is greatly limited.
The content of the invention
In order to solve facial mask liquid in the prior art, there are function is single, security is relatively low, anti-inflammatory, antiallergic effect are poor to be lacked
Fall into, it is an object of the invention to provide one kind to have antiallergic of releiving, and prevents bacterium from invading and harassing, and eliminates skin itching and scytitis work(
Effect, and higher facial mask liquid containing Folium Artemisiae Argyi extractive liquid of security and preparation method thereof, to solve drawbacks described above.
The present invention provides a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid, including following component and its parts by weight：
8-16 parts of Folium Artemisiae Argyi extractive liquid, 5-10 parts of moutan bark extracting solution, 4-8 parts of hazel extract, compound amino acid 2-6
Part, 0.1-0.5 parts of carboxymethyl chitosan, 0.2-0.6 parts of hydroxyethyl cellulose, 0.1-0.5 parts of allantoin, 1-5 parts of propane diols, penta
70-90 parts of 1-3 parts of glycol, 3-8 parts of glycerine, 0.1-0.5 parts of preservative and water.
Further, the facial mask liquid containing Folium Artemisiae Argyi extractive liquid includes following component and its parts by weight：
12 parts of Folium Artemisiae Argyi extractive liquid, 8 parts of moutan bark extracting solution, 6 parts of hazel extract, 4 parts of compound amino acid, carboxymethyl shell
0.4 part of glycan, 0.3 part of hydroxyethyl cellulose, 0.3 part of allantoin, 3 parts of propane diols, 2 parts of pentanediol, 6 parts of glycerine, preservative 0.2
80 parts of part and water.
Further, the preparation method of the Folium Artemisiae Argyi extractive liquid is：Dry folium artemisiae argyi is taken, is crushed, adds folium artemisiae argyi coarse powder weight
10-15 times of concentration is the ethanol of 60-80%, and heating and refluxing extraction 2-3 time, is filtered, merging filtrate, by decompression filtrate recycling ethanol,
Obtain Folium Artemisiae Argyi extractive liquid.
Further, the preparation method of the moutan bark extracting solution is：Take moutan bark to crush, add moutan bark coarse powder weight
12-15 times of water is measured, adds the sodium chloride of medicinal material amount 5-10%, soaks 5-10h, steam distillation is carried out, obtains moutan bark extracting solution.
Further, the preparation method of the hazel extract is：Take witch hazel branches and leaves to crush, add witch hazel coarse powder
5-8 times of concentration of weight is the ethanol of 60-80%, and ultrasonic wave extraction 2-3 times, each 1-2h, is filtered, merging filtrate, by filtrate decompression
Ethanol is recycled, obtains hazel extract.
Further, the preservative is one kind or its composition in Phenoxyethanol and Sensiva SC50.
Folium Artemisiae Argyi extractive liquid in facial mask liquid provided by the invention containing Folium Artemisiae Argyi extractive liquid contain abundant volatile oil, flavones,
Eudesmane and triterpene substance, it has effects that antiallergy, antifatigue, anti-oxidant and sterilization, and to no skin irritation,
It is a kind of pure natural, non-stimulated cosmetic composition.
Modern study finds that moutan bark extracting solution has inhibitory action to the elastoser of metalloproteinases, to organizing egg
White enzyme has activation, shows that moutan bark extracting solution has the function of skin-active and anti-ageing, with reference to the antioxidant of moutan bark extracting solution,
There is obvious anti-aging effect to skin.In hazel extract containing a variety of tanning matters and it is a variety of releive, convergent work
Property component, there is anti-inflammatory, antiallergy, relax stimulated skin, convergence pore, moisturizing, the effect of moisturizing.
Compound amino acid is the natural wetting factor in keratoderma, and the skin of aging, hardening can be made to recover hydrability,
Can effectively prevent cuticula moisture loss, make skin moisten with it is flexible.Carboxymethyl chitosan is a kind of water soluble chitosan
Derivative, has the function that antibacterial, fresh-keeping, is conducive to extend the shelf-life of product.Allantoin is a kind of nontoxic, tasteless, stingless
Swash property, without hypersensitive white crystal, it, which has, promotes cell growth, accelerates wound healing, cutin-softening albumen, is sterilized, only
Bitterly, oxidation resistant effect, makes skin exquisiteness, water tender, dynamic.
Bactericidal properties of the facial mask liquid provided by the invention containing Folium Artemisiae Argyi extractive liquid with wide spectrum, antiallergy, anti-inflammatory, promotion cell
The effect of growth and quickening wound healing, while also there is moisturizing, moisturizing.Skin is set to moisten exquisiteness, have bullet after use
Property, it is a kind of facial mask liquid for meeting modern's requirement.Facial mask liquid provided by the invention containing Folium Artemisiae Argyi extractive liquid soaks nothing when applying
Woven fabric mask, every leaching 30g containing facial mask liquid, obtains facial mask finished product.Warm water cleaning face first is equipped with face cleaning product during use,
Film cloth is unfolded inwardly to be lightly spread in face, flicking applies 15 ~ 20 minutes, weekly using 2 ~ 3 times to complete fitting.
In addition, present invention also offers a kind of preparation method of the facial mask liquid containing Folium Artemisiae Argyi extractive liquid, comprise the following steps：
S1 heats water to 50-80 DEG C, adds allantoin, stirs to being completely dissolved, obtains allantoin liquid；
Glycerine, propane diols and pentanediol are added in carboxymethyl chitosan and hydroxyethyl cellulose and stirred evenly by S2, are obtained mixed
Close liquid；
The allantoin liquid that step S1 is obtained is uniformly mixed by S3 with the obtained mixed liquors of step S2, is subsequently added into folium artemisiae argyi extraction
Liquid, moutan bark extracting solution, hazel extract, compound amino acid and preservative, stir evenly, to obtain the final product.
Compared with prior art, the facial mask liquid provided by the invention containing Folium Artemisiae Argyi extractive liquid has the advantage that：
（1）Bactericidal properties of the facial mask liquid provided by the invention containing Folium Artemisiae Argyi extractive liquid with wide spectrum, antiallergy, anti-inflammatory, promotion
Cell growth and the effect of accelerate wound healing, while also has the function that moisturizing, moisturizing, is a kind of to meet modern and require
Facial mask liquid；
（2）For facial mask liquid provided by the invention containing Folium Artemisiae Argyi extractive liquid to no skin irritation, long-time service is not in skin
The phenomenon of skin poisoning, is a kind of healthy, multi-functional facial mask liquid, is conducive to the large-scale production and sale of the facial mask liquid.
Brief description of the drawings
Fig. 1 is vegetative map of the facial mask liquid containing Folium Artemisiae Argyi extractive liquid to HACAT cells；
Fig. 2 is the wound healing figure of HACAT cells；
Fig. 3 is wound healing figure of the facial mask liquid containing Folium Artemisiae Argyi extractive liquid to HACAT cells.
Embodiment
Below by way of the description of embodiment, the invention will be further described, but this is not the limit to the present invention
System, those skilled in the art's basic thought according to the present invention, various modifications may be made or improves, but without departing from this
The basic thought of invention, within the scope of the present invention.The each component of the present invention is conventional commercial product, such as：Allantois
Element is purchased from Merck KGaA company, model：RonaCare Allantion 101015；Compound amino acid is purchased from hundred bright moral of South Korea
Company, model Amino Acid Complex (B).
The preparation of embodiment 1, Folium Artemisiae Argyi extractive liquid
Dry folium artemisiae argyi is taken, is crushed, adds 10 times of concentration of folium artemisiae argyi coarse powder weight as 70% ethanol, heating and refluxing extraction 2 times,
Filtering, merging filtrate, by decompression filtrate recycling ethanol, obtains Folium Artemisiae Argyi extractive liquid.
The preparation of embodiment 2, moutan bark extracting solution
Take moutan bark to crush, add moutan bark coarse powder 12 times of water of weight, add the sodium chloride of medicinal material amount 5%, soak 5h, into
Row steam distillation, obtains moutan bark extracting solution.
The preparation of embodiment 3, hazel extract
Take witch hazel branches and leaves to crush, add 5 times of concentration of witch hazel coarse powder weight as 70% ethanol, ultrasonic wave extraction 2 times,
Each 1.5h, filtering, merging filtrate, by decompression filtrate recycling ethanol, obtains hazel extract.
Embodiment 4, a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
The facial mask liquid containing Folium Artemisiae Argyi extractive liquid includes following component and its parts by weight：
8 parts of Folium Artemisiae Argyi extractive liquid, 5 parts of moutan bark extracting solution, 4 parts of hazel extract, 2 parts of compound amino acid, carboxymethyl shell
0.1 part of glycan, 0.2 part of hydroxyethyl cellulose, 0.1 part of allantoin, 2 parts of propane diols, 1 part of pentanediol, 4 parts of glycerine, Phenoxyethanol
0.1 part and 70 parts of water.
Preparation method：
S1 heats water to 50 DEG C, adds allantoin, stirs to being completely dissolved, obtains allantoin liquid；
Glycerine, propane diols and pentanediol are added in carboxymethyl chitosan and hydroxyethyl cellulose and stirred evenly by S2, are obtained mixed
Close liquid；
The allantoin liquid that step S1 is obtained is uniformly mixed by S3 with the obtained mixed liquors of step S2, is subsequently added into folium artemisiae argyi extraction
Liquid, moutan bark extracting solution, hazel extract, compound amino acid and preservative, stir evenly, to obtain the final product.
Embodiment 5, a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
The facial mask liquid containing Folium Artemisiae Argyi extractive liquid includes following component and its parts by weight：
12 parts of Folium Artemisiae Argyi extractive liquid, 8 parts of moutan bark extracting solution, 6 parts of hazel extract, 4 parts of compound amino acid, carboxymethyl shell
0.4 part of glycan, 0.3 part of hydroxyethyl cellulose, 0.3 part of allantoin, 3 parts of propane diols, 2 parts of pentanediol, 6 parts of glycerine, ethylhexyl
80 parts of 0.2 part of glycerine and water.
Preparation method is similar to Example 4.
Embodiment 6, a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
The facial mask liquid containing Folium Artemisiae Argyi extractive liquid includes following component and its parts by weight：
16 parts of Folium Artemisiae Argyi extractive liquid, 10 parts of moutan bark extracting solution, 8 parts of hazel extract, 6 parts of compound amino acid, carboxymethyl
0.5 part of chitosan, 0.6 part of hydroxyethyl cellulose, 0.5 part of allantoin, 5 parts of propane diols, 3 parts of pentanediol, 8 parts of glycerine, benzene oxygen second
90 parts of 0.3 part of alcohol and water.
Preparation method is similar to Example 4.
Comparative example 1, a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
The facial mask liquid containing Folium Artemisiae Argyi extractive liquid includes following component and its parts by weight：
12 parts of Folium Artemisiae Argyi extractive liquid, 6 parts of hazel extract, 4 parts of compound amino acid, 0.4 part of carboxymethyl chitosan, ethoxy
80 parts of 0.3 part of cellulose, 0.3 part of allantoin, 3 parts of propane diols, 2 parts of pentanediol, 6 parts of glycerine, 0.2 part of Phenoxyethanol and water.
Preparation method is similar to Example 4.
Comparative example 2, a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
The facial mask liquid containing Folium Artemisiae Argyi extractive liquid includes such as component and its parts by weight：
12 parts of Folium Artemisiae Argyi extractive liquid, 8 parts of moutan bark extracting solution, 6 parts of hazel extract, 4 parts of compound amino acid, carboxymethyl shell
0.4 part of glycan, 0.3 part of hydroxyethyl cellulose, 3 parts of propane diols, 2 parts of pentanediol, 6 parts of glycerine, 0.2 part of Sensiva SC50 and water
80 parts.
Preparation method is similar to Example 4.
The bacteriostatic test of test example one, facial mask liquid containing Folium Artemisiae Argyi extractive liquid
1st, test material：Facial mask containing Folium Artemisiae Argyi extractive liquid prepared by embodiment 4, embodiment 5, embodiment 6 and comparative example 1
Liquid.
2nd, for the preparation of examination bacterium
Escherichia coli, staphylococcus aureus, Dipel, bacillus subtilis are connect respectively in sterile room
Aspergillus, brewer's yeast and Candida are seeded in bean sprout juice nutrient solution, in 28-30 DEG C of bar by kind into beef extract nutrient solution
1-3d is cultivated under part.
3rd, test method：
Diffusion method is punched using agar, sterile petri dish is divided into 5 groups, every group 4, by the beef extract nutrient solution after sterilizing
Pour into sterile petri dish, per 15 ~ 20mL of ware, 0.1mL Escherichia coli, golden yellow Portugal are drawn with Sterile pipette after its solidification
Grape coccus, Dipel and bacillus subtilis are added on culture dish for examination bacterium, and coating is uniform, and every group of each culture dish adds
Different strains.
Sterile petri dish is divided into 5 groups, every group 3, the bean sprout juice nutrient solution after sterilizing is poured into sterile petri dish, often
15 ~ 20mL of ware, training is added to after its solidification with Sterile pipette absorption 0.1mL aspergillus, brewer's yeast and Candida for examination bacterium
Support on ware, coating is uniform, and every group of each culture dish adds different strains.
After coating, 5 equidistant holes are then made a call on culture medium with the sterilizing stainless steel card punch of outside diameter 4mm.
The facial mask containing Folium Artemisiae Argyi extractive liquid prepared with micro sample adding appliance difference extraction embodiment 4, embodiment 5, embodiment 6 and comparative example 1
30 μ L of liquid, middle hole addition equivalent sterile water do control group, carry out mark.Bacterium is placed at 37 DEG C and cultivates 24h, by mould
It is placed in yeast at 28 DEG C and cultivates 72h.Measure antibacterial circle diameter（Bacteriostatic diameter mm is counted）, experiment is repeated 5 times, with 5 average values
For antibacterial circle diameter.
4th, result of the test
Result of the test is as shown in table 1.
The bacteriostatic test data of facial mask liquid of the table 1 containing Folium Artemisiae Argyi extractive liquid
As shown in Table 1, the facial mask liquid containing Folium Artemisiae Argyi extractive liquid for preparing of the present invention to Escherichia coli, staphylococcus aureus,
Dipel and bacillus subtilis have significant inhibitory action, have to aspergillus, brewer's yeast and Candida preferable
Inhibitory action, and comparative example 1 has lacked moutan bark extracting solution, it is to Dipel, bacillus subtilis, aspergillus, beer
The fungistatic effect of yeast and Candida is poor, illustrates that Folium Artemisiae Argyi extractive liquid, moutan bark extracting solution and hazel extract mixing make
With enhancing bacteriostasis can be cooperateed with.
Test example two, the experiment of the skin repair of facial mask liquid containing Folium Artemisiae Argyi extractive liquid
1st, test material：Facial mask liquid containing Folium Artemisiae Argyi extractive liquid prepared by embodiment 5, HACAT cells, are purchased from Shanghai Bo Gu lifes
Thing Science and Technology Ltd., article No. BG183.
2nd, test method：
Take the logarithm the HACAT cells in growth period, be inoculated in 96 well culture plates, per hole 100uL.It is placed in 37 DEG C, 5%CO2Bar
Overnight incubation under part.The concentration dilution for the facial mask liquid containing Folium Artemisiae Argyi extractive liquid for being prepared embodiment 5 with DMEM culture mediums is
3.125th, 6.25,12.5,25,50 and 100mg/mL.Next day takes out cell plates, abandons supernatant, and various concentrations are separately added into per hole
Facial mask liquid, per hole 100uL, each concentration does 6 multiple holes.To be not added with the HACAT cells of facial mask liquid as normal cell group, 37
℃、5% CO2Under the conditions of cultivate 24h.Then the MTT solution 10uL that concentration is 5mg/mL are added in every hole successively, continue to be incubated
4h.Culture supernatant 100uL in hole is discarded, add 100uL DMSO fully shakings then at every hole fully dissolves to crystal.
570nm wavelength is selected on enzyme-linked immunosorbent assay instrument, measures each hole absorbance value（OD values）.
3rd, result of the test：
Result of the test is as shown in Figure 1.Facial mask liquid containing Folium Artemisiae Argyi extractive liquid prepared by the present invention can promote HACAT cells
Propagation, with the increase of facial mask liquid concentration, the proliferation rate of HACAT cells is in downward trend after first rising, in facial mask liquid concentration
For 6.25mg/mL when, the proliferation rate of HACAT cells reaches peak value, and the proliferation rate of subsequent HACAT cells is on a declining curve.
The wound healing experiment of test example three, facial mask liquid containing Folium Artemisiae Argyi extractive liquid
1st, test material：Embodiment 5 prepares the facial mask liquid containing Folium Artemisiae Argyi extractive liquid, and HACAT cells, are purchased from Shanghai Bo Gu biologies
Science and Technology Ltd., article No. BG183.
2nd, test method：
Take the logarithm the HACAT cells in growth period, be inoculated in 6 well culture plates, treat that HACAT cells 100% merge, in 6 holes
The equidistant horizontal line of back stroke.Using 100uL pipette tips in cell monolayer longitudinal scratch, culture cell wound model is caused.
It is grouped at random after cut, is respectively control group and test group, the cell maintenance medium of control group equivalent is handled, and test group uses
Facial mask liquid containing Folium Artemisiae Argyi extractive liquid processing prepared by the embodiment 5 that concentration is 6.25mg/mL.After having handled observation cut with it is drawn
Situation of change near horizontal line joint, and take pictures respectively in 0,6,12,24h, the width of cut is measured under fluorescence microscope.
3rd, result of the test
As shown in Figures 2 and 3, wherein A is control group to result of the test, and B is test group.Prepared by the addition present invention contains folium artemisiae argyi
The facial mask liquid of extracting solution can be effectively promoted HACAT cell migrations fusion, illustrate it is of the invention prepare containing Folium Artemisiae Argyi extractive liquid
Facial mask liquid can promote the healing rate of wound.
The evaluation test of test example four, facial mask liquid containing Folium Artemisiae Argyi extractive liquid
1st, test material：Prepared by embodiment 4, embodiment 5, embodiment 6, comparative example 1 and comparative example 2 extracts containing folium artemisiae argyi
Facial mask made of the facial mask liquid of liquid.
2nd, tested crowd：Choose 50 female volunteers, the age between 20 ~ 40 years old, volunteer's selection criteria：It is sensitive
Property skin, face have the female volunteers of small pox or erythema.
3rd, test method：
Volunteer is randomly divided into 5 groups, is respectively 4 groups of embodiment, 5 groups of embodiment, 6 groups of embodiment, 1 group of comparative example and right
2 groups of ratio, every group of 10 people.After each group volunteer cleans face, corresponding facial mask is got, the face of being lightly spread in is unfolded in facial mask inwardly
Portion, flicking apply 15 minutes, weekly using 2 times to complete fitting.
Use the moisturizing effect after 4 weeks to the facial mask liquid containing Folium Artemisiae Argyi extractive liquid, antipruritic, irritation, anti-inflammatory effects and entirety
Effect is evaluated, and evaluation method is：
（1）Moisturizing effect：A effects are fine, and B effects are good, and C effects are general, and D does not have effect；
（2）It is antipruritic：A effects are fine, and B effects are good, and C effects are general, and D does not have effect；
（3）Irritation：A is non-stimulated, and B is stimulated a little, but without it is red, itch, C has stimulation, have it is red, itch, D stimulate, it is red, swollen；
（4）Anti-inflammatory effects：A effects are fine, and the swelling and pain of small pox or erythema are disappeared, and B effects are good, and small pox or erythema are without pain
Sense, C effects are general, and the swelling and pain of small pox or erythema also exist, and D does not have effect, and small pox or erythema swelling and pain are serious；
（5）Overall effect：A effects are fine, and B effects are good, and C effects are general, and D does not have effect.
4th, result of the test：
Result of the test is as shown in table 2.
Facial mask liquid of the table 2 containing Folium Artemisiae Argyi extractive liquid is tried out（4 weeks）Feed back conclusive table
| 4 groups of embodiment | 5 groups of embodiment | 6 groups of embodiment | 1 group of comparative example | 2 groups of comparative example | |
| Moisturizing effect | B | A | B | A | C |
| It is antipruritic | A | A | A | C | A |
| Irritation | A | A | A | B | B |
| Anti-inflammatory effects | A | A | A | C | A |
| Overall effect | A | A | A | C | B |
As shown in Table 2, the facial mask liquid containing Folium Artemisiae Argyi extractive liquid that prepared by the present invention has in moisturizing, antipruritic, anti-inflammatory etc.
Obvious action, and overall assessment effect is fine, is a kind of facial mask liquid for meeting modern's requirement.
Claims (4)
1. a kind of facial mask liquid containing Folium Artemisiae Argyi extractive liquid, it is characterised in that including following component and its parts by weight：
8-16 parts of Folium Artemisiae Argyi extractive liquid, 5-10 parts of moutan bark extracting solution, 4-8 parts of hazel extract, 2-6 parts of compound amino acid, carboxylic
0.1-0.5 parts of methyl chitosan, 0.2-0.6 parts of hydroxyethyl cellulose, 0.1-0.5 parts of allantoin, 1-5 parts of propane diols, pentanediol
70-90 parts of 1-3 parts, 3-8 parts of glycerine, 0.1-0.5 parts of preservative and water；
Wherein, the preparation method of the Folium Artemisiae Argyi extractive liquid is：Dry folium artemisiae argyi is taken, is crushed, it is dense to add 10-15 times of folium artemisiae argyi coarse powder weight
The ethanol for 60-80% is spent, heating and refluxing extraction 2-3 times, filtering, merging filtrate, by decompression filtrate recycling ethanol, obtains folium artemisiae argyi and carry
Take liquid；
Wherein, the preparation method of the moutan bark extracting solution is：Take moutan bark to crush, add 12-15 times of moutan bark coarse powder weight
Water, adds the sodium chloride of medicinal material amount 5-10%, soaks 5-10h, carries out steam distillation, obtains moutan bark extracting solution；
Wherein, the preparation method of the hazel extract is：Take witch hazel branches and leaves to crush, add witch hazel coarse powder weight 5-8
Times concentration is the ethanol of 60-80%, and ultrasonic wave extraction 2-3 time, each 1-2h, is filtered, merging filtrate, second is recycled by filtrate decompression
Alcohol, obtains hazel extract.
2. the facial mask liquid containing Folium Artemisiae Argyi extractive liquid as claimed in claim 1, it is characterised in that including following component and its parts by weight
Number：
12 parts of Folium Artemisiae Argyi extractive liquid, 8 parts of moutan bark extracting solution, 6 parts of hazel extract, 4 parts of compound amino acid, carboxymethyl chitosan
0.4 part, 0.3 part of hydroxyethyl cellulose, 0.3 part of allantoin, 3 parts of propane diols, 2 parts of pentanediol, 6 parts of glycerine, 0.2 part of preservative and
80 parts of water.
3. the facial mask liquid containing Folium Artemisiae Argyi extractive liquid as claimed in claim 1 or 2, it is characterised in that the preservative is benzene oxygen second
One kind or its composition in alcohol and Sensiva SC50.
A kind of 4. preparation method of facial mask liquid containing Folium Artemisiae Argyi extractive liquid as described in claim 1-3 is any, it is characterised in that bag
Include following steps：
S1 heats water to 50-80 DEG C, adds allantoin, stirs to being completely dissolved, obtains allantoin liquid；
Glycerine, propane diols and pentanediol are added in carboxymethyl chitosan and hydroxyethyl cellulose and stirred evenly by S2, obtain mixed liquor；
The allantoin liquid that step S1 is obtained is uniformly mixed by S3 with the obtained mixed liquors of step S2, be subsequently added into Folium Artemisiae Argyi extractive liquid,
Moutan bark extracting solution, hazel extract, compound amino acid and preservative, stir evenly, to obtain the final product.
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| CN107375082A (en) * | 2017-08-08 | 2017-11-24 | 湖北瑞晟生物有限责任公司 | A kind of moisturizing anti-inflammatory facial mask liquid and preparation method thereof |
| CN108371642B (en) * | 2018-03-09 | 2020-11-24 | 广东暨晴生物医药科技有限公司 | Spring balance water and preparation method thereof |
| CN110859864A (en) * | 2019-12-05 | 2020-03-06 | 江苏食品药品职业技术学院 | Preparation process of folium artemisiae argyi extract and application of folium artemisiae argyi extract in preparation of acute kidney injury medicine |
| CN113398622A (en) * | 2021-05-14 | 2021-09-17 | 暨南大学 | Supercritical CO2Method for preparing wormwood raw pulp by extraction and molecular distillation processes |
| CN114903821A (en) * | 2021-07-08 | 2022-08-16 | 包计贤 | A facial mask rich in natural medicine and its preparation method |
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