CN105188569B - 用于递送活性剂的微结构阵列 - Google Patents

用于递送活性剂的微结构阵列 Download PDF

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Publication number
CN105188569B
CN105188569B CN201480015948.2A CN201480015948A CN105188569B CN 105188569 B CN105188569 B CN 105188569B CN 201480015948 A CN201480015948 A CN 201480015948A CN 105188569 B CN105188569 B CN 105188569B
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China
Prior art keywords
microstructure
polysaccharide
active agent
microstructure array
array
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CN201480015948.2A
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English (en)
Chinese (zh)
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CN105188569A (zh
Inventor
陈国华
丁中立
E·加提-泰格
P·辛格
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Corian Co
Corium LLC
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Corian Co
Corium International Inc
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Publication of CN105188569A publication Critical patent/CN105188569A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201480015948.2A 2013-03-15 2014-03-07 用于递送活性剂的微结构阵列 Active CN105188569B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361800543P 2013-03-15 2013-03-15
US61/800,543 2013-03-15
PCT/US2014/022087 WO2014150069A1 (en) 2013-03-15 2014-03-07 Microstructure array for delivery of active agents

Publications (2)

Publication Number Publication Date
CN105188569A CN105188569A (zh) 2015-12-23
CN105188569B true CN105188569B (zh) 2020-11-20

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US (1) US20140276378A1 (cg-RX-API-DMAC7.html)
EP (2) EP4059450A1 (cg-RX-API-DMAC7.html)
JP (1) JP2016518868A (cg-RX-API-DMAC7.html)
KR (1) KR102316739B1 (cg-RX-API-DMAC7.html)
CN (1) CN105188569B (cg-RX-API-DMAC7.html)
AU (1) AU2014237499B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015022432B1 (cg-RX-API-DMAC7.html)
CA (1) CA2904335C (cg-RX-API-DMAC7.html)
ES (1) ES2921174T3 (cg-RX-API-DMAC7.html)
IL (1) IL241064A0 (cg-RX-API-DMAC7.html)
MX (1) MX2015012433A (cg-RX-API-DMAC7.html)
RU (1) RU2662432C2 (cg-RX-API-DMAC7.html)
WO (1) WO2014150069A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201506916B (cg-RX-API-DMAC7.html)

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Also Published As

Publication number Publication date
AU2014237499B2 (en) 2018-11-15
JP2016518868A (ja) 2016-06-30
CA2904335A1 (en) 2014-09-25
KR102316739B1 (ko) 2021-10-26
US20140276378A1 (en) 2014-09-18
RU2015143551A (ru) 2017-04-20
EP4059450A1 (en) 2022-09-21
RU2662432C2 (ru) 2018-07-26
BR112015022432A2 (pt) 2017-07-18
EP2967597A1 (en) 2016-01-20
ZA201506916B (en) 2016-12-21
KR20150126883A (ko) 2015-11-13
CA2904335C (en) 2022-03-29
IL241064A0 (en) 2015-11-30
BR112015022432A8 (pt) 2019-11-26
EP2967597B1 (en) 2022-05-04
CN105188569A (zh) 2015-12-23
BR112015022432B1 (pt) 2022-02-15
AU2014237499A1 (en) 2015-09-17
MX2015012433A (es) 2016-02-03
ES2921174T3 (es) 2022-08-19
WO2014150069A1 (en) 2014-09-25

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