JP2016518868A - 活性剤の送達のための微細構造物のアレイ - Google Patents

活性剤の送達のための微細構造物のアレイ Download PDF

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Publication number
JP2016518868A
JP2016518868A JP2016500904A JP2016500904A JP2016518868A JP 2016518868 A JP2016518868 A JP 2016518868A JP 2016500904 A JP2016500904 A JP 2016500904A JP 2016500904 A JP2016500904 A JP 2016500904A JP 2016518868 A JP2016518868 A JP 2016518868A
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JP
Japan
Prior art keywords
active agent
array
liquid formulation
polysaccharide
microstructured
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Pending
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JP2016500904A
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English (en)
Japanese (ja)
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JP2016518868A5 (cg-RX-API-DMAC7.html
Inventor
グオファ チェン，
グオファ チェン，
ゾングリ ディン，
ゾングリ ディン，
エサイ ガーティー−タゴエ，
エサイ ガーティー−タゴエ，
パーミンダー シン，
パーミンダー シン，
Original Assignee
コリウム インターナショナル， インコーポレイテッド
コリウム インターナショナル， インコーポレイテッド
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Application filed by コリウム インターナショナル， インコーポレイテッド, コリウム インターナショナル， インコーポレイテッド filed Critical コリウム インターナショナル， インコーポレイテッド
Publication of JP2016518868A publication Critical patent/JP2016518868A/ja
Publication of JP2016518868A5 publication Critical patent/JP2016518868A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016500904A 2013-03-15 2014-03-07 活性剤の送達のための微細構造物のアレイ Pending JP2016518868A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361800543P 2013-03-15 2013-03-15
US61/800,543 2013-03-15
PCT/US2014/022087 WO2014150069A1 (en) 2013-03-15 2014-03-07 Microstructure array for delivery of active agents

Publications (2)

Publication Number Publication Date
JP2016518868A true JP2016518868A (ja) 2016-06-30
JP2016518868A5 JP2016518868A5 (cg-RX-API-DMAC7.html) 2017-04-06

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JP2016500904A Pending JP2016518868A (ja) 2013-03-15 2014-03-07 活性剤の送達のための微細構造物のアレイ

Country Status (14)

Country Link
US (1) US20140276378A1 (cg-RX-API-DMAC7.html)
EP (2) EP4059450A1 (cg-RX-API-DMAC7.html)
JP (1) JP2016518868A (cg-RX-API-DMAC7.html)
KR (1) KR102316739B1 (cg-RX-API-DMAC7.html)
CN (1) CN105188569B (cg-RX-API-DMAC7.html)
AU (1) AU2014237499B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015022432B1 (cg-RX-API-DMAC7.html)
CA (1) CA2904335C (cg-RX-API-DMAC7.html)
ES (1) ES2921174T3 (cg-RX-API-DMAC7.html)
IL (1) IL241064A0 (cg-RX-API-DMAC7.html)
MX (1) MX2015012433A (cg-RX-API-DMAC7.html)
RU (1) RU2662432C2 (cg-RX-API-DMAC7.html)
WO (1) WO2014150069A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201506916B (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020507422A (ja) * 2017-02-17 2020-03-12 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 活性成分を含むマイクロニードルアレイ
JP2020099513A (ja) * 2018-12-21 2020-07-02 ロレアル マイクロニードルシートを使用するキット及び美容方法

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WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
ES2634667T3 (es) * 2009-04-24 2017-09-28 Corium International, Inc. Métodos para fabricar conjuntos de microproyección
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
EP3881781B1 (en) 2011-10-12 2023-03-29 Vaxxas Pty Limited Delivery device
KR102265808B1 (ko) 2012-12-21 2021-06-16 코리움, 인크. 치료제의 전달을 위한 마이크로어레이 및 그것의 사용방법
EP2968887B1 (en) 2013-03-12 2022-05-04 Corium, Inc. Microprojection applicators
JP2016512754A (ja) 2013-03-15 2016-05-09 コリウム インターナショナル， インコーポレイテッド 治療剤の送達のためのマイクロアレイ、使用方法および製造方法
EP4194028A1 (en) 2013-03-15 2023-06-14 Corium Pharma Solutions, Inc. Multiple impact microprojection applicators
CN105246458B (zh) 2013-03-15 2020-09-15 考里安公司 用于治疗剂递送的微阵列及其使用方法
EP2968116A1 (en) 2013-03-15 2016-01-20 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
WO2015093452A1 (ja) * 2013-12-16 2015-06-25 武田薬品工業株式会社 マイクロニードル
US20160279401A1 (en) 2015-03-27 2016-09-29 Allergan, Inc. Dissolvable microneedles for skin treatment
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EP3193828B8 (en) * 2014-08-29 2023-04-05 Corium Pharma Solutions, Inc. Microstructure array for delivery of active agents
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
JP6906885B2 (ja) * 2014-11-14 2021-07-21 ロレアル しわを減少させるためのマイクロニードルシート
CA2975275C (en) 2015-02-02 2023-08-29 Vaxxas Pty Limited Microprojection array applicator and method
KR101667216B1 (ko) * 2015-06-18 2016-10-18 방철환 약물 주입 장치
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP2017051312A (ja) * 2015-09-08 2017-03-16 富士フイルム株式会社 マイクロニードルアレイ
WO2017045031A1 (en) 2015-09-18 2017-03-23 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
KR101610598B1 (ko) * 2015-09-21 2016-04-07 비엔엘바이오테크 주식회사 잇몸 굴곡에 맞게 유연하며 치과용 물질 전달을 위한 마이크로 니들 및 그 제작방법
EP3355981B1 (en) 2015-09-28 2025-11-19 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
EP3434314B1 (en) * 2016-03-25 2022-11-09 Toppan Printing Co., Ltd. Transdermal delivery device
KR101719319B1 (ko) * 2016-04-05 2017-03-23 주식회사 엘지생활건강 효율적인 피부 천공을 위한 마이크로니들 구조
CN109310827B (zh) 2016-04-08 2021-09-07 阿勒根公司 抽吸和注射装置
WO2017208962A1 (ja) * 2016-05-31 2017-12-07 Ｎｉｓｓｈａ株式会社 マイクロニードルアレイ及びその製造方法
US20180056053A1 (en) * 2016-08-26 2018-03-01 Juvic Inc. Protruding microstructure for transdermal delivery
CN106474620A (zh) * 2016-09-22 2017-03-08 北京化工大学 一种药物可控释放的聚合物微针、制备方法及微针贴片
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WO2018220926A1 (ja) * 2017-05-30 2018-12-06 Ｎｉｓｓｈａ株式会社 マイクロニードルパッチとその梱包体
CA3065371A1 (en) 2017-06-13 2018-12-20 Vaxxas Pty Limited Quality control of substrate coatings
AU2018309562A1 (en) 2017-08-04 2020-02-20 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (MAP)
JP6671616B2 (ja) * 2017-11-02 2020-03-25 コスメディ製薬株式会社 歯科用局所麻酔マイクロニードルアレイ
JP7305311B2 (ja) * 2018-05-30 2023-07-10 ロレアル マイクロニードルシート
JP2020018327A (ja) * 2018-07-17 2020-02-06 ロレアル マイクロニードルシート
JP2022505334A (ja) * 2018-10-18 2022-01-14 スリーエム イノベイティブ プロパティズ カンパニー 構造化表面を有する歯科装具
CN109498804B (zh) * 2018-12-04 2022-07-26 中国人民解放军军事科学院军事医学研究院 一种温度响应型狂犬疫苗递送系统
JP6778296B2 (ja) * 2019-04-11 2020-10-28 富士フイルム株式会社 マイクロニードルアレイ
KR20250056504A (ko) 2023-10-19 2025-04-28 연세대학교 산학협력단 분리 수율이 높은 마이크로니들 구조체, 이를 포함하는 장치 및 이의 제조 방법

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JP2020507422A (ja) * 2017-02-17 2020-03-12 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 活性成分を含むマイクロニードルアレイ
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JP2020099513A (ja) * 2018-12-21 2020-07-02 ロレアル マイクロニードルシートを使用するキット及び美容方法

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AU2014237499B2 (en) 2018-11-15
CA2904335A1 (en) 2014-09-25
CN105188569B (zh) 2020-11-20
KR102316739B1 (ko) 2021-10-26
US20140276378A1 (en) 2014-09-18
RU2015143551A (ru) 2017-04-20
EP4059450A1 (en) 2022-09-21
RU2662432C2 (ru) 2018-07-26
BR112015022432A2 (pt) 2017-07-18
EP2967597A1 (en) 2016-01-20
ZA201506916B (en) 2016-12-21
KR20150126883A (ko) 2015-11-13
CA2904335C (en) 2022-03-29
IL241064A0 (en) 2015-11-30
BR112015022432A8 (pt) 2019-11-26
EP2967597B1 (en) 2022-05-04
CN105188569A (zh) 2015-12-23
BR112015022432B1 (pt) 2022-02-15
AU2014237499A1 (en) 2015-09-17
MX2015012433A (es) 2016-02-03
ES2921174T3 (es) 2022-08-19
WO2014150069A1 (en) 2014-09-25

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