CN104906494A - Traditional Chinese medicine composition for treating irregular menstruation - Google Patents
Traditional Chinese medicine composition for treating irregular menstruation Download PDFInfo
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- CN104906494A CN104906494A CN201510313322.6A CN201510313322A CN104906494A CN 104906494 A CN104906494 A CN 104906494A CN 201510313322 A CN201510313322 A CN 201510313322A CN 104906494 A CN104906494 A CN 104906494A
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Abstract
The invention provides a traditional Chinese medicine composition for treating irregular menstruation. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 12 parts of sansevieria trifasciata prain, 10 parts of clerodendrum fortunatum roots, 20 parts of fructus amomi, 12 parts of radix paeoniae alba, 30 parts of oyster, 20 parts of rhizoma curculiginis, 12 parts of herba epimedii, 20 parts of golden cypress, 10 parts of ligusticum wallichii, 30 parts of keel, 15 parts of rhizoma anemarrhenae, 10 fructus psoraleae, 12 parts of angelica sinensis, 15 parts of rehmannia, 8 parts of cinnamon, 15 parts of motherwort and 10 parts of liquorice. The invention discloses a preparation method of the traditional Chinese medicine composition. The irregular menstruation can be treated by the traditional Chinese medicine composition.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of Chinese medicine composition being used for the treatment of menoxenia and its preparation method and application.
Background technology
Menoxenia Xi Shi gynecological common disease, shows as the exception of menstrual cycle or amount of bleeding, can accompany that the moon is premenstrual, menstrual period time stomachache and General Symptoms.The cause of disease may be organic disease or malfunction.For this reason, be bursting to and develop the needs that more medicines for the treatment of menoxenia safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of menoxenia disease.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of Chinese medicine composition being used for the treatment of menoxenia, the active component contained by it is extracted by following weight crude drug and is prepared from: blue 12 parts of Budgerigar, Radix Clerodendri Fortunati 10 parts, Fructus Amomi 20 parts, the Radix Paeoniae Alba 12 parts, Concha Ostreae 30 parts, Rhizoma Curculiginis 20 parts, Herba Epimedii 12 parts, Cortex Phellodendri 20 parts, Rhizoma Chuanxiong 10 parts, Os Draconis 30 parts, the Rhizoma Anemarrhenae 15 parts, Fructus Psoraleae 10 parts, Radix Angelicae Sinensis 12 parts, Radix Rehmanniae 15 parts, Cortex Cinnamomi 8 parts, Herba Leonuri 15 parts, 10 parts, Radix Glycyrrhizae.
The described Chinese medicine composition being used for the treatment of menoxenia, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described Chinese medicine composition being used for the treatment of menoxenia, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The described application of Chinese medicine composition in preparation treatment menoxenia medicine being used for the treatment of menoxenia.
Above-mentioned Budgerigar is blue, Latin literary fame: Sansevieria trifasciata Prain, and for Liliaceae, Folium Sansevieriae Trifasclatae belong to perennial evergreen herbaceous plant, rhizome grows in shape of crawling, acaulescence.Plant height can reach about 1 meter, and blade is grown thickly and uprightly, plump keratin, all there is irregular dirty-green cloud layer shape band on two sides, gains the name as brave tail.Have horizontal walk root stock.Phyllopodium is raw, normal 1 ~ 2 piece, also has 3 ~ 6 pieces of clusters, uprightly, hard leather matter, flat, but cultivate in family and often lose that the flowers are in blossom, to appreciate blade.Heat-clearing and toxic substances removing, removing the necrotic tissue and promoting granulation.For cold cough, bronchitis, traumatic injury; Carbuncle pyogenic infections from tumour or sore is controlled in external, venom.The present invention is with all herbal medicine.Radix Clerodendri Fortunati is root or the root bark of Verbenaceae Fructus Seu Herba Pubescentis, and Classification system Clerodendron fortunatum L, has the effects such as heat clearing away, removing toxic substances, removing heat from blood, pain relieving, the symptom such as cure mainly cold, fever, bloody dysentery, skin ulcer scabies, scrofula, swell and ache.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: Budgerigar orchid of the present invention, Radix Clerodendri Fortunati, Fructus Amomi, the Radix Paeoniae Alba, Concha Ostreae, Rhizoma Curculiginis heat clearing away, regulating menstruation are monarch drug, Herba Epimedii, Cortex Phellodendri, Rhizoma Chuanxiong, Os Draconis, the Rhizoma Anemarrhenae, Fructus Psoraleae, Radix Angelicae Sinensis, Radix Rehmanniae blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain are ministerial drug, Cortex Cinnamomi, Herba Leonuri, Radix Glycyrrhizae are adjuvant, mediation pig medicine, full side's compatibility, heat clearing away, regulating menstruation, blood circulation promoting and blood stasis dispelling, treatment menoxenia successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get the blue 12g of Budgerigar, Radix Clerodendri Fortunati 10g, Fructus Amomi 20g, Radix Paeoniae Alba 12g, Concha Ostreae 30g, Rhizoma Curculiginis 20g, Herba Epimedii 12g, Cortex Phellodendri 20g, Rhizoma Chuanxiong 10g, Os Draconis 30g, Rhizoma Anemarrhenae 15g, Fructus Psoraleae 10g, Radix Angelicae Sinensis 12g, Radix Rehmanniae 15g, Cortex Cinnamomi 8g, Herba Leonuri 15g, Radix Glycyrrhizae 10g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get the blue 12g of Budgerigar, Radix Clerodendri Fortunati 10g, Fructus Amomi 20g, Radix Paeoniae Alba 12g, Concha Ostreae 30g, Rhizoma Curculiginis 20g, Herba Epimedii 12g, Cortex Phellodendri 20g, Rhizoma Chuanxiong 10g, Os Draconis 30g, Rhizoma Anemarrhenae 15g, Fructus Psoraleae 10g, Radix Angelicae Sinensis 12g, Radix Rehmanniae 15g, Cortex Cinnamomi 8g, Herba Leonuri 15g, Radix Glycyrrhizae 10g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get the blue 12g of Budgerigar, Radix Clerodendri Fortunati 10g, Fructus Amomi 20g, Radix Paeoniae Alba 12g, Concha Ostreae 30g, Rhizoma Curculiginis 20g, Herba Epimedii 12g, Cortex Phellodendri 20g, Rhizoma Chuanxiong 10g, Os Draconis 30g, Rhizoma Anemarrhenae 15g, Fructus Psoraleae 10g, Radix Angelicae Sinensis 12g, Radix Rehmanniae 15g, Cortex Cinnamomi 8g, Herba Leonuri 15g, Radix Glycyrrhizae 10g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, fill, make capsule.
4, traditional Chinese medicine composition for treating menoxenia clinical research of the present invention
4.1 general data: this Chinese medicine composition is applied to clinical observation menoxenia case 100 example, 16 ~ 35 years old age.The shortest person of the course of disease 4 months, most elder reaches 3 years, average 1.5 years.
4.2 diagnostic criterias:
4.2.1 infrequent menstruation a: menstrual blood loss is less than 10 milliliters or few and all wets to two layers of paper not saturating, even if hypomenorrhea.
4.2.2 change in menstrual cycle: repeatedly change in menstrual cycle more than 7 days persons.
4.2.3 menorrhagia: be that in continuous several menstrual cycle, BTB amount is many, but menstruation interval time and bleeding time are all regular, without the unexpected increase of intermenstrual bleeding, postcoital bleeding or menses.There is the class in ovulation type dysfunctional uterine bleeding in system.
4.3 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within five days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule five days is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.4 criterions of therapeutical effect: clinical recovery: menstrual cycle recovers normal, and menstrual blood volume is normal, maintains more than 3 months.Take a turn for the better: menstrual cycle recovers normal, and menstrual blood volume is normal, but can not maintain more than 3 months.Invalid: menstrual cycle and menstrual blood volume have no improvement.
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
Treatment group | 50 | 15 | 25 | 10 | 80 |
Blank group | 50 | 2 | 4 | 34 | 12.5 |
Visible the present invention has good therapeutic effect to menoxenia, and toxic and side effects does not occur treatments period.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine composition of menoxenia, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: blue 12 parts of Budgerigar, Radix Clerodendri Fortunati 10 parts, Fructus Amomi 20 parts, the Radix Paeoniae Alba 12 parts, Concha Ostreae 30 parts, Rhizoma Curculiginis 20 parts, Herba Epimedii 12 parts, Cortex Phellodendri 20 parts, Rhizoma Chuanxiong 10 parts, Os Draconis 30 parts, the Rhizoma Anemarrhenae 15 parts, Fructus Psoraleae 10 parts, Radix Angelicae Sinensis 12 parts, Radix Rehmanniae 15 parts, Cortex Cinnamomi 8 parts, Herba Leonuri 15 parts, 10 parts, Radix Glycyrrhizae.
2. be used for the treatment of the Chinese medicine composition of menoxenia as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. be used for the treatment of the Chinese medicine composition of menoxenia as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. be used for the treatment of the application of Chinese medicine composition in treatment menoxenia medicine of menoxenia according to claim 1.
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1628840A (en) * | 2004-08-17 | 2005-06-22 | 石春荣 | Medicine for promoting ovulation and aiding pregnancy |
CN101181594A (en) * | 2007-11-20 | 2008-05-21 | 高光 | Health care beverage for preventing and controlling menorrhalgia |
CN103861036A (en) * | 2014-03-13 | 2014-06-18 | 张保全 | Body-regulating and incubation-promoting pill |
CN104491315A (en) * | 2015-01-09 | 2015-04-08 | 卞毓平 | Traditional Chinese medicine composition for treating irregular menstrual period |
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- 2015-06-09 CN CN201510313322.6A patent/CN104906494A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1628840A (en) * | 2004-08-17 | 2005-06-22 | 石春荣 | Medicine for promoting ovulation and aiding pregnancy |
CN101181594A (en) * | 2007-11-20 | 2008-05-21 | 高光 | Health care beverage for preventing and controlling menorrhalgia |
CN103861036A (en) * | 2014-03-13 | 2014-06-18 | 张保全 | Body-regulating and incubation-promoting pill |
CN104491315A (en) * | 2015-01-09 | 2015-04-08 | 卞毓平 | Traditional Chinese medicine composition for treating irregular menstrual period |
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