CN104813168B - 需要pd‑l1抑制剂综合疗法的患者的鉴定 - Google Patents
需要pd‑l1抑制剂综合疗法的患者的鉴定 Download PDFInfo
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- CN104813168B CN104813168B CN201380062234.2A CN201380062234A CN104813168B CN 104813168 B CN104813168 B CN 104813168B CN 201380062234 A CN201380062234 A CN 201380062234A CN 104813168 B CN104813168 B CN 104813168B
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- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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- C12Q2600/00—Oligonucleotides characterized by their use
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- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70532—B7 molecules, e.g. CD80, CD86
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
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- Urology & Nephrology (AREA)
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- Animal Behavior & Ethology (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12195182.6 | 2012-11-30 | ||
| EP12195182 | 2012-11-30 | ||
| EP12196177.5 | 2012-12-07 | ||
| EP12196177 | 2012-12-07 | ||
| PCT/EP2013/075162 WO2014083178A1 (en) | 2012-11-30 | 2013-11-29 | Identification of patients in need of pd-l1 inhibitor cotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104813168A CN104813168A (zh) | 2015-07-29 |
| CN104813168B true CN104813168B (zh) | 2017-10-20 |
Family
ID=49886877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380062234.2A Active CN104813168B (zh) | 2012-11-30 | 2013-11-29 | 需要pd‑l1抑制剂综合疗法的患者的鉴定 |
Country Status (10)
| Country | Link |
|---|---|
| US (7) | US20160333414A1 (https=) |
| EP (2) | EP2926142B2 (https=) |
| JP (2) | JP6998646B2 (https=) |
| KR (1) | KR102291355B1 (https=) |
| CN (1) | CN104813168B (https=) |
| BR (1) | BR112015012644A2 (https=) |
| CA (1) | CA2889298C (https=) |
| MX (1) | MX363188B (https=) |
| RU (1) | RU2692773C2 (https=) |
| WO (1) | WO2014083178A1 (https=) |
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| TWI472339B (zh) | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至her2結構域ii之抗體及其酸性變異體的組合物 |
| BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
| AU2009333580B2 (en) | 2008-12-09 | 2016-07-07 | Genentech, Inc. | Anti-PD-L1 antibodies and their use to enhance T-cell function |
| WO2013055874A2 (en) | 2011-10-14 | 2013-04-18 | Genentech, Inc. | Uses for and article of manufacture including her2 dimerization inhibitor pertuzumab |
| US20130330761A1 (en) | 2012-06-12 | 2013-12-12 | Celcuity, LLC | Whole cell assays and methods |
| KR102389677B1 (ko) | 2013-03-15 | 2022-04-21 | 제넨테크, 인크. | Pd-1 및 pd-l1 관련 상태를 치료하기 위한 바이오마커 및 방법 |
| RU2019115089A (ru) | 2013-04-16 | 2019-06-11 | Дженентек, Инк. | Варианты пертузумаба и их аналитическая характеристика |
| WO2015095404A2 (en) | 2013-12-17 | 2015-06-25 | Genentech, Inc. | Methods of treating cancers using pd-1 axis binding antagonists and taxanes |
| UA129760C2 (uk) | 2013-12-17 | 2025-07-30 | Дженентек, Інк. | Анти-cd3 антитіло та спосіб його застосування |
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| TWI731861B (zh) | 2015-06-16 | 2021-07-01 | 美商建南德克公司 | FcRH5之人源化及親和力成熟抗體及使用方法 |
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| CN105717298A (zh) * | 2016-01-29 | 2016-06-29 | 浙江数问生物技术有限公司 | Pd-l1免疫组化试剂盒 |
| RU2767329C2 (ru) * | 2016-02-06 | 2022-03-17 | Эпимаб Биотерапьютикс, Инк. | Иммуноглобулин с тандемными fab-фрагментами и варианты его применения |
| KR20250065735A (ko) | 2016-03-14 | 2025-05-13 | 에프. 호프만-라 로슈 아게 | Pd-l1 발현의 감소를 위한 올리고뉴클레오티드 |
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| US20220090212A1 (en) | 2022-03-24 |
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| RU2692773C2 (ru) | 2019-06-27 |
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| CN104813168A (zh) | 2015-07-29 |
| US20160333414A1 (en) | 2016-11-17 |
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| MX2015006756A (es) | 2015-08-05 |
| CA2889298C (en) | 2024-01-02 |
| US20180274038A1 (en) | 2018-09-27 |
| US20220282337A1 (en) | 2022-09-08 |
| EP3511718A1 (en) | 2019-07-17 |
| US20200199690A1 (en) | 2020-06-25 |
| HK1208911A1 (en) | 2016-03-18 |
| EP2926142B1 (en) | 2018-11-07 |
| MX363188B (es) | 2019-03-13 |
| EP2926142B2 (en) | 2022-07-06 |
| US20220170115A1 (en) | 2022-06-02 |
| JP7181854B2 (ja) | 2022-12-01 |
| JP2020099324A (ja) | 2020-07-02 |
| KR102291355B1 (ko) | 2021-08-19 |
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