CN104721757A - Traditional Chinese medicine composition used for treating irritable bowel syndromes - Google Patents
Traditional Chinese medicine composition used for treating irritable bowel syndromes Download PDFInfo
- Publication number
- CN104721757A CN104721757A CN201510176545.2A CN201510176545A CN104721757A CN 104721757 A CN104721757 A CN 104721757A CN 201510176545 A CN201510176545 A CN 201510176545A CN 104721757 A CN104721757 A CN 104721757A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- irritable bowel
- chinese medicine
- medicine composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides traditional Chinese medicine composition used for treating irritable bowel syndromes. The traditional Chinese medicine composition is prepared by radix psudostellariae, rhizome atractylodis macrocephalae, poria cocos and the like and is used for treating the irritable bowel syndromes.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of Chinese medicine composition being used for the treatment of irritable bowel syndrome and its preparation method and application.
Background technology
Irritable bowel syndrome (IBS) is one group to be continued or interval outbreak, and to suffer from abdominal pain, abdominal distention, bowl evacuation habit and (or) stool change into clinical manifestation, and lack the function of intestinal canal disorder disease of gastrointestinal tract structure and biochemistry exception.Classical symptom is stomachache, the abdominal distention relevant to abnormal defecation, is divided into according to cardinal symptom: diarrhea predominance type; Constipation leading type; Alternating diarrhea and constipation type.The factors such as spirit, diet, cold can be lured symptom recurrence into or be increased the weight of.Because sickness rate is high, for this reason, be bursting to and develop the needs that more medicines for the treatment of irritable bowel syndrome safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of irritable bowel syndrome disease.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of Chinese medicine composition being used for the treatment of irritable bowel syndrome, the active component contained by it is extracted by following weight crude drug and is prepared from: Herba Hieracii Umbellati 16 parts, headdress flower Herba crotalariae mucronatae 14 parts, Radix Pseudostellariae 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 10 parts, Poria, Semen Coicis 15 parts, Radix Curcumae 10 parts, Radix Saposhnikoviae 6 parts, Radix Paeoniae Rubra 10 parts, Pericarpium Citri Reticulatae 6 parts, the Rhizoma Pinelliae 10 parts, Fructus Amomi 4 parts, Radix Bupleuri 10,5 parts, Radix Glycyrrhizae.
The described Chinese medicine composition being used for the treatment of irritable bowel syndrome, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described Chinese medicine composition being used for the treatment of irritable bowel syndrome, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The described application of Chinese medicine composition in preparation treatment irritable bowel syndrome medicine being used for the treatment of irritable bowel syndrome.
Herba Hieracii Umbellati source Compositae hawk weed Herba Hieracii Umbellati HieraciumumbelatumL., with root and all herbal medicine, heat-clearing and toxic substances removing, dampness removing removing food stagnancy.For carbuncle furuncle, urinary tract infection, the long-pending block of stomachache, dysentery.The present invention is with root and all herbal medicine.Headdress flower Herba crotalariae mucronatae is pulse family Genus Crotalaria Linn headdress flower Herba crotalariae mucronatae Crotalaria capitata Benth., is used as medicine with root.Autumn adopts, and cleans and dries.Heat-clearing and toxic substances removing, antidiarrheal.For infantile pneumonia, infantile diarrhea, furuncle furuncle, traumatic injury, trauma infection contamination.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: in the present invention, Chinese medicine Herba Hieracii Umbellati, headdress flower Herba crotalariae mucronatae, Radix Pseudostellariae, Rhizoma Atractylodis Macrocephalae heat-clearing and toxic substances removing, dispersing the stagnated live-QI to relieve the stagnation of QI are monarch drug, Poria, Semen Coicis, Radix Curcumae, Radix Saposhnikoviae, Radix Paeoniae Rubra, Pericarpium Citri Reticulatae, the Rhizoma Pinelliae, Fructus Amomi, Radix Bupleuri regulating QI to relieve pain are ministerial drug, Radix Glycyrrhizae is adjuvant, coordinating the actions of various ingredients in a prescription, treatment irritable bowel syndrome successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Herba Hieracii Umbellati 16g, headdress flower Herba crotalariae mucronatae 14g, Radix Pseudostellariae 10g, Rhizoma Atractylodis Macrocephalae 10g, Poria 10g, Semen Coicis 15g, Radix Curcumae 10g, Radix Saposhnikoviae 6g, Radix Paeoniae Rubra 10g, Pericarpium Citri Reticulatae 6g, Rhizoma Pinelliae 10g, Fructus Amomi 4g, Radix Bupleuri 10, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Herba Hieracii Umbellati 16g, headdress flower Herba crotalariae mucronatae 14g, Radix Pseudostellariae 10g, Rhizoma Atractylodis Macrocephalae 10g, Poria 10g, Semen Coicis 15g, Radix Curcumae 10g, Radix Saposhnikoviae 6g, Radix Paeoniae Rubra 10g, Pericarpium Citri Reticulatae 6g, Rhizoma Pinelliae 10g, Fructus Amomi 4g, Radix Bupleuri 10, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get Herba Hieracii Umbellati 16g, headdress flower Herba crotalariae mucronatae 14g, Radix Pseudostellariae 10g, Rhizoma Atractylodis Macrocephalae 10g, Poria 10g, Semen Coicis 15g, Radix Curcumae 10g, Radix Saposhnikoviae 6g, Radix Paeoniae Rubra 10g, Pericarpium Citri Reticulatae 6g, Rhizoma Pinelliae 10g, Fructus Amomi 4g, Radix Bupleuri 10, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, fill, make capsule.
4, traditional Chinese medicine composition for treating irritable bowel syndrome of the present invention clinical research
4.1 general data: this Chinese medicine composition is applied to clinical observation irritable bowel syndrome case 50 example, and at 36 ~ 48 years old age, men and women half and half, average 1 year of the course of disease.
4.2 diagnostic criterias: the stomachache of recurrent exerbation or discomfort (discomfort mean feel under the weather but not pain), in nearest 3 months, every month has at least 3 days to occur symptom, merges following 2 or many: 1. remission after defecation; 2. change with stool during outbreak; 3. change with stool (outward appearance) during outbreak.
4.3 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within one month, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule one month is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.4 criterions of therapeutical effect: cure: patient clinical transference cure, stool is shaped, and be no more than 2 every day, continuous February does not recur; Effective: patient is conscious, and clinical symptoms obviously alleviates, stool is shaped, and occasionally has diarrhoea; Invalid: the conscious clinical symptoms of patient is without improvement or increase the weight of.
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Cure | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 30 | 14 | 12 | 4 | 86.7 |
| Blank group | 20 | 0 | 1 | 19 | 5 |
Visible the present invention has good therapeutic effect to irritable bowel syndrome, and toxic and side effects does not occur treatments period.
4.6 model cases:
Zhang, man, 38 years old, recurrent exerbation stomachache in nearly 3 months, remission after defecation, every day defecation frequency not etc., be diagnosed as irritable bowel syndrome, take and prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within one month, be a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Patient's clinical symptom disappearance after one month, stool is shaped, and is no more than 2 every day, within continuous 6 months, does not recur.
Claims (2)
1. one kind is used for the treatment of the Chinese medicine composition of irritable bowel syndrome, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba Hieracii Umbellati 16 parts, headdress flower Herba crotalariae mucronatae 14 parts, Radix Pseudostellariae 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 10 parts, Poria, Semen Coicis 15 parts, Radix Curcumae 10 parts, Radix Saposhnikoviae 6 parts, Radix Paeoniae Rubra 10 parts, Pericarpium Citri Reticulatae 6 parts, the Rhizoma Pinelliae 10 parts, Fructus Amomi 4 parts, Radix Bupleuri 10,5 parts, Radix Glycyrrhizae.
2. be used for the treatment of the application of Chinese medicine composition in treatment irritable bowel syndrome medicine of irritable bowel syndrome according to claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510176545.2A CN104721757A (en) | 2015-04-14 | 2015-04-14 | Traditional Chinese medicine composition used for treating irritable bowel syndromes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510176545.2A CN104721757A (en) | 2015-04-14 | 2015-04-14 | Traditional Chinese medicine composition used for treating irritable bowel syndromes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104721757A true CN104721757A (en) | 2015-06-24 |
Family
ID=53446553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510176545.2A Withdrawn CN104721757A (en) | 2015-04-14 | 2015-04-14 | Traditional Chinese medicine composition used for treating irritable bowel syndromes |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104721757A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103845702A (en) * | 2012-12-05 | 2014-06-11 | 中国中医科学院西苑医院 | Traditional Chinese medicinal composition for treating irritable bowel syndrome and preparation method of composition |
| CN104324113A (en) * | 2014-10-17 | 2015-02-04 | 叶祖光 | Drug for treatment of irritable bowel syndrome and preparation method thereof |
-
2015
- 2015-04-14 CN CN201510176545.2A patent/CN104721757A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103845702A (en) * | 2012-12-05 | 2014-06-11 | 中国中医科学院西苑医院 | Traditional Chinese medicinal composition for treating irritable bowel syndrome and preparation method of composition |
| CN104324113A (en) * | 2014-10-17 | 2015-02-04 | 叶祖光 | Drug for treatment of irritable bowel syndrome and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101224282A (en) | Medicine compounds for treating infantile anorexia and preparing method thereof | |
| CN104013756A (en) | Traditional Chinese medicine composition for preventing and treating diarrhea and application of traditional Chinese medicine composition | |
| CN105832991A (en) | Traditional Chinese medicine composition for treating gastritis | |
| CN111821329A (en) | Application of ginseng in regulating intestinal microorganisms | |
| CN104435567A (en) | Traditional Chinese medicinal composition containing gynostemma pentaphyllum for treating gout | |
| CN103495120B (en) | A kind of Chinese medicine composition for the treatment of pelvic inflammatory disease and preparation method thereof | |
| CN102988921B (en) | Chinese medicinal composition for treating diarrhea as well as preparation method and application thereof | |
| CN105250552A (en) | Pharmaceutical preparation used for treating acute gastroenteritis | |
| CN104784621A (en) | Traditional Chinese medicine composition for treating diarrhea, and preparation method and application thereof | |
| CN104800681A (en) | Traditional Chinese medicine composition for treating irregular menstruation | |
| CN101502583A (en) | Chinese medicament preparation for treating cholecystitis and gall-stone as well as preparation method thereof | |
| CN104888137A (en) | Medicinal preparation for treatment of polycystic ovarian syndrome | |
| CN104721757A (en) | Traditional Chinese medicine composition used for treating irritable bowel syndromes | |
| CN103816265B (en) | A kind ofly be used for the treatment of medicine of having loose bowels and preparation method thereof | |
| CN105267639A (en) | Pharmaceutical preparation used for treating chronic gastritis | |
| CN101450133A (en) | Medicine for treating abdominopelvic cavity disease postoperative intestinal adhesion | |
| CN105148078A (en) | Medicinal preparation used for treating oral ulcers | |
| CN105079717A (en) | Pharmaceutical preparation for treating depression | |
| CN105055806A (en) | Medicinal preparation for treating diarrhea | |
| CN104840759A (en) | Medicine preparation used for treating dyspepsia | |
| CN105232712A (en) | Pharmaceutical preparation for treating irregular menstruation | |
| CN105125996A (en) | Pharmaceutical preparation for treating unstable angina pectoris of aged coronary heart disease | |
| CN105169064A (en) | Medicinal preparation for whitening skin | |
| CN105055702A (en) | Pharmaceutical preparation for treating chronic pelvic inflammatory disease | |
| CN104784662A (en) | Traditional Chinese medicine composition for treating anxiety |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20150624 |