CN104487424A - 用于生产dfmb衍生物的方法 - Google Patents

用于生产dfmb衍生物的方法 Download PDF

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Publication number
CN104487424A
CN104487424A CN201280070516.2A CN201280070516A CN104487424A CN 104487424 A CN104487424 A CN 104487424A CN 201280070516 A CN201280070516 A CN 201280070516A CN 104487424 A CN104487424 A CN 104487424A
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CN
China
Prior art keywords
group
compound
formula
hydroxyl
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280070516.2A
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English (en)
Chinese (zh)
Inventor
T.张
C.梅西耶
O.比西纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhodia Operations SAS
Original Assignee
Rhodia Operations SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodia Operations SAS filed Critical Rhodia Operations SAS
Publication of CN104487424A publication Critical patent/CN104487424A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201280070516.2A 2012-02-20 2012-02-20 用于生产dfmb衍生物的方法 Pending CN104487424A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2012/071346 WO2013123634A1 (en) 2012-02-20 2012-02-20 Process for production of dfmb derivatives

Publications (1)

Publication Number Publication Date
CN104487424A true CN104487424A (zh) 2015-04-01

Family

ID=49004911

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280070516.2A Pending CN104487424A (zh) 2012-02-20 2012-02-20 用于生产dfmb衍生物的方法

Country Status (6)

Country Link
US (1) US9458119B2 (https=)
EP (1) EP2817294B1 (https=)
JP (1) JP5963222B2 (https=)
CN (1) CN104487424A (https=)
IN (1) IN2014DN07014A (https=)
WO (1) WO2013123634A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI572228B (zh) * 2015-03-05 2017-02-21 宏達國際電子股份有限公司 行動裝置與其功能執行方法

Citations (6)

* Cited by examiner, † Cited by third party
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CN1760184A (zh) * 2005-11-10 2006-04-19 上海大学 2－二氟甲基氨基苯并咪唑及其制备方法
CN1760185A (zh) * 2005-11-10 2006-04-19 上海大学 含氟硝基苯并咪唑的制备方法
CN101016276A (zh) * 2007-02-09 2007-08-15 上海大学 5－硝基－2－二氟甲基苯并咪唑及其合成方法
CN101016274A (zh) * 2007-02-09 2007-08-15 上海大学 5－氯－2－二氟甲基苯并噁唑及其合成方法
US20070244110A1 (en) * 2006-04-14 2007-10-18 Zenyaku Kogyo Kabushiki Kaisha Treatment of prostate cancer, melanoma or hepatic cancer
CN101595103A (zh) * 2006-09-14 2009-12-02 阿斯利康(瑞典)有限公司 嘧啶衍生物

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DE2326624A1 (de) * 1973-05-25 1974-12-12 Hoechst Ag Neue benzimidazolderivate
US4122184A (en) * 1973-09-14 1978-10-24 Eli Lilly And Company Benzimidazole insecticides
GB9518552D0 (en) 1995-09-11 1995-11-08 Fujisawa Pharmaceutical Co New heterocyclic compounds
JP4077054B2 (ja) * 1996-05-24 2008-04-16 三共アグロ株式会社 ベンゾチアゾール及びベンゾオキサゾール誘導体の製法
US20040224952A1 (en) * 2003-05-07 2004-11-11 Cowart Marlon D. Fused bicyclic-substituted amines as histamine-3 receptor ligands
WO2008032077A1 (en) * 2006-09-14 2008-03-20 Astrazeneca Ab Pyrimidine derivatives
CN100465166C (zh) * 2007-02-09 2009-03-04 上海大学 5-甲基-2-二氟甲基苯并噁唑及其合成方法
US20120165309A1 (en) * 2009-02-12 2012-06-28 Astellas Pharma Inc. Hetero ring derivative
SG174527A1 (en) * 2009-03-27 2011-11-28 Pathway Therapeutics Inc Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
PH12012500252A1 (en) 2009-08-07 2015-06-26 Chugai Pharmaceutical Co Ltd Aminopyrazole derivative
WO2011107504A1 (de) * 2010-03-04 2011-09-09 Bayer Cropscience Ag Fluoralkyl- substituierte 2 -amidobenzimidazole und deren verwendung zur steigerung der stresstoleranz in pflanzen

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1760184A (zh) * 2005-11-10 2006-04-19 上海大学 2－二氟甲基氨基苯并咪唑及其制备方法
CN1760185A (zh) * 2005-11-10 2006-04-19 上海大学 含氟硝基苯并咪唑的制备方法
US20070244110A1 (en) * 2006-04-14 2007-10-18 Zenyaku Kogyo Kabushiki Kaisha Treatment of prostate cancer, melanoma or hepatic cancer
CN101595103A (zh) * 2006-09-14 2009-12-02 阿斯利康(瑞典)有限公司 嘧啶衍生物
CN101016276A (zh) * 2007-02-09 2007-08-15 上海大学 5－硝基－2－二氟甲基苯并咪唑及其合成方法
CN101016274A (zh) * 2007-02-09 2007-08-15 上海大学 5－氯－2－二氟甲基苯并噁唑及其合成方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FENGLIAN GE ET AL.: "One-pot synthesis of 2-trifluoromethyl and 2-difluoromethyl substituted benzo-1,3-diazoles", 《TETRAHEDRON LETTERS》 *
FENGLIAN GE ET AL.: "One-pot synthesis of 2-trifluoromethyl and 2-difluoromethyl substituted benzo-1,3-diazoles", 《TETRAHEDRON LETTERS》, vol. 48, 7 March 2007 (2007-03-07) *

Also Published As

Publication number Publication date
EP2817294B1 (en) 2017-12-27
WO2013123634A1 (en) 2013-08-29
EP2817294A1 (en) 2014-12-31
JP5963222B2 (ja) 2016-08-03
IN2014DN07014A (https=) 2015-04-10
EP2817294A4 (en) 2015-07-29
US20150005505A1 (en) 2015-01-01
US9458119B2 (en) 2016-10-04
JP2015506991A (ja) 2015-03-05

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Application publication date: 20150401