CN1043348C - 不对称取代的黄嘌呤、其制备方法及其作为药物组合物的应用 - Google Patents

不对称取代的黄嘌呤、其制备方法及其作为药物组合物的应用 Download PDF

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Publication number
CN1043348C
CN1043348C CN93109282A CN93109282A CN1043348C CN 1043348 C CN1043348 C CN 1043348C CN 93109282 A CN93109282 A CN 93109282A CN 93109282 A CN93109282 A CN 93109282A CN 1043348 C CN1043348 C CN 1043348C
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China
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group
refer
formula
och
xanthine
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Expired - Fee Related
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CN93109282A
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English (en)
Chinese (zh)
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CN1086818A (zh
Inventor
乌瑞克·库克诺-穆尔
赫尔曼特·恩森格
约切姆·米耶雷
弗朗兹·约瑟夫·库
埃里奇·莱尔
恩齐欧·米勒
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Boehringer Ingelheim GmbH
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Boehringer Ingelheim GmbH
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Publication of CN1086818A publication Critical patent/CN1086818A/zh
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Anticipated expiration legal-status Critical
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN93109282A 1992-08-10 1993-08-10 不对称取代的黄嘌呤、其制备方法及其作为药物组合物的应用 Expired - Fee Related CN1043348C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4226371 1992-08-10
DEP4226371.9 1992-08-10
DE4238423 1992-11-13
DEP4238423.0 1992-11-13

Publications (2)

Publication Number Publication Date
CN1086818A CN1086818A (zh) 1994-05-18
CN1043348C true CN1043348C (zh) 1999-05-12

Family

ID=25917371

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93109282A Expired - Fee Related CN1043348C (zh) 1992-08-10 1993-08-10 不对称取代的黄嘌呤、其制备方法及其作为药物组合物的应用

Country Status (21)

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US (1) US5719279A (US20050026921A1-20050203-C00045.png)
EP (1) EP0654033A1 (US20050026921A1-20050203-C00045.png)
JP (1) JPH08500344A (US20050026921A1-20050203-C00045.png)
KR (1) KR950702988A (US20050026921A1-20050203-C00045.png)
CN (1) CN1043348C (US20050026921A1-20050203-C00045.png)
AU (1) AU681348B2 (US20050026921A1-20050203-C00045.png)
BG (1) BG62618B1 (US20050026921A1-20050203-C00045.png)
CA (1) CA2140883A1 (US20050026921A1-20050203-C00045.png)
CZ (1) CZ286459B6 (US20050026921A1-20050203-C00045.png)
FI (1) FI950542A (US20050026921A1-20050203-C00045.png)
HU (1) HUT65734A (US20050026921A1-20050203-C00045.png)
IL (1) IL106624A (US20050026921A1-20050203-C00045.png)
MX (1) MX9304819A (US20050026921A1-20050203-C00045.png)
NZ (1) NZ254804A (US20050026921A1-20050203-C00045.png)
PL (1) PL176389B1 (US20050026921A1-20050203-C00045.png)
RU (1) RU2138500C1 (US20050026921A1-20050203-C00045.png)
SG (1) SG55038A1 (US20050026921A1-20050203-C00045.png)
SK (1) SK18595A3 (US20050026921A1-20050203-C00045.png)
TW (1) TW252044B (US20050026921A1-20050203-C00045.png)
UA (1) UA46697C2 (US20050026921A1-20050203-C00045.png)
WO (1) WO1994003456A1 (US20050026921A1-20050203-C00045.png)

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Also Published As

Publication number Publication date
RU2138500C1 (ru) 1999-09-27
NZ254804A (en) 1997-01-29
IL106624A0 (en) 1993-12-08
CZ286459B6 (en) 2000-04-12
RU95109100A (ru) 1996-12-27
BG62618B1 (bg) 2000-03-31
FI950542A0 (fi) 1995-02-08
BG99489A (bg) 1996-01-31
IL106624A (en) 1999-01-26
SG55038A1 (en) 1998-12-21
WO1994003456A1 (de) 1994-02-17
HUT65734A (en) 1994-07-28
JPH08500344A (ja) 1996-01-16
SK18595A3 (en) 1995-07-11
US5719279A (en) 1998-02-17
AU4707193A (en) 1994-03-03
AU681348B2 (en) 1997-08-28
CN1086818A (zh) 1994-05-18
MX9304819A (es) 1994-02-28
HU9302302D0 (en) 1993-10-28
PL176389B1 (pl) 1999-05-31
CZ34895A3 (en) 1995-10-18
PL307397A1 (en) 1995-05-15
KR950702988A (ko) 1995-08-23
UA46697C2 (uk) 2002-06-17
CA2140883A1 (en) 1994-02-17
FI950542A (fi) 1995-02-08
TW252044B (US20050026921A1-20050203-C00045.png) 1995-07-21
EP0654033A1 (de) 1995-05-24

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