CN104257528B - A kind of active Chinese drug component compositions and the application in cosmetics thereof - Google Patents
A kind of active Chinese drug component compositions and the application in cosmetics thereof Download PDFInfo
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Abstract
The invention discloses a kind of active Chinese drug component compositions and the application in cosmetics thereof.The raw material of described active Chinese drug component compositions includes shrubby sophora extract, licorice, phellodendron extract, coptis extract, Baical Skullcap root P.E, radix paeoniae alba extraction, Rhizoma Atractylodis Macrocephalae extract, purslane extract；Above-mentioned natural plant extracts is compounded by a certain percentage with water, glycerine, is prepared as natural traditional Chinese medicine active matter vegetable composition, composition stable in physicochemical property, be difficult to crystallization, add simple to technique in cosmetics；It is added simultaneously in cosmetics, carry out efficacy assessments mensuration, result can have suppression and the effect improved to symptoms such as dry skin, rubescent, itch, eczemas, the combination of this natural plant extracts can be applicable in emulsifying cream or emulsion, all kinds of surfactant, elite can also be added on, in the care product such as products such as wet tissue, play moisturizing, anti-effect such as quick, anti-inflammatory and reparation.
Description
Technical field
The invention belongs to daily use chemicals technical field, particularly to a kind of active Chinese drug component compositions and answering in cosmetics thereof
With.
Background technology
China is that skin care item sell big country, along with raising and the change of the consumption consciousness of people's level of consumption, advocates nature
Become the common recognition of more and more people with back to nature, cosmetics safety is required more and more higher by consumer, and production development becomes
Certainly will must be the biodegradable product of environmental protection.Have very much with the both effectiveness product of natural plants especially medicinal herb components and send out
Exhibition potentiality, have superiority most especially for for Chinese market.China's herbal remedies mask in the application has advantageous condition,
Effect activity of research Chinese herbal medicine.The present invention, by adding vegetable active thing, gives cosmetics special functional, has wide
Market prospects and social effect.The market speedup of whole world natural cosmetics exceeded far away other kinds of product in recent years, flat
All annual growths are close to 10%.It is reported that the product of child-resistant is such as prevented and treated the products such as eczema, infantile eczema and Quick itch stopping and also existed
Quickly increase.
Childhood eczema, as a kind of common anaphylactia, is the superficial dermis and epidermis caused by multiple internal and external factor
Inflammation, has and significantly oozes out tendency, and the course of disease is long, the most repeatedly.Wherein chronic eczema patient ratio is higher, and the incidence of disease is gone up year by year
Rising, especially infant morbidity has reached 75.7%, more with autumn and winter.Most of hospitals are for childhood eczema symptom often
Opening hormone medicine such as Eloson etc. to reach anti-quick antipruritic effect, the tender and lovely skin of children, under the stimulation of hormone, on the contrary can
Derive even more serious symptom, usually periods of months and do not get better.Therefore, exploitation possesses the green functional of suppression eczema effect
Property youth puerility cosmetic, have broad application prospects and huge market potential.
Natural traditional Chinese medicine plant extracts is to inherit and developing thousand of years traditional medication experiences of China and the base of theory advantage
On plinth, use for reference medical standards and the specification of international endorsement, use effective medicinal ingredient of modern pharmaceutical technology gained.Ancient times " thousand
Jin Yifang " record clearing heat and promoting diuresis kuh-seng soup, kuh-seng (eight liang) rheum officinale (three liang) frutus cnidii (one liter) Chinese herbaceous peony (three liang) root of large-flowered skullcap
(two liang) golden cypress (five liang) coptis (three liang) greenbrier (one jin) upper eight tastes, cut, struggle against with water three, boil and take a pipeful of half, wash it, day three
Degree, the best.Prescriptions Worth Thousand Gold for Emergencies is controlled children's's fire and is burnt sore, has to the greatest extent numb beans all over the body, or has pus, first the pain the most first side of itching: Radix Glycyrrhizae, in vain
Chinese herbaceous peony, radix ampelopsis, the root of large-flowered skullcap, the coptis, golden cypress, kuh-seng (half and half liang), upper seven tastes are end, with honey with apply it, at night one day two, also can cook soup and wash
It.These two doses of sides utilize external application, thus reach the effect that Cutaneous permeation absorbs, and current tcm clinical practice often quotes above two prescriptions
Treatment childhood eczema.After compounding for this type of traditional Chinese medical science prescription extract interpolation, apply in youth puerility cosmetic so that it is possess treatment and
Effect of suppression childhood eczema, market potential is big.But current natural traditional Chinese medicine plant extracts there is also many very important
Problem have impact on its application, such as: water-soluble, poor stability, and biological half-life is short, and skin absorptance is low, and degraded is fast；Especially
After multiple natural traditional Chinese medicine plant extracts compounded combination, easily producing precipitation, bin stability is poor, the active matter effect after combination
Suppressed etc..Therefore solve the problems referred to above and become the technological difficulties that natural traditional Chinese medicine plant is widely used in cosmetics.
Summary of the invention
For the problems referred to above, it is an object of the invention to provide a kind of active Chinese drug component compositions and answering in cosmetics thereof
With.The described unable stable in properties of active Chinese drug component compositions, is difficult to crystallization, adds it in cosmetics not only technique simple,
And the symptoms such as dry skin, rubescent, itch, eczema can be had suppression and the effect improved.
It is an object of the invention to be achieved through the following technical solutions:
A kind of active Chinese drug component compositions, the raw material of described composition includes that shrubby sophora extract, licorice, golden cypress carry
Take thing, coptis extract, Baical Skullcap root P.E, radix paeoniae alba extraction, Rhizoma Atractylodis Macrocephalae extract, purslane extract, the weight of described each raw material
Amount portion rate is:
Shrubby sophora extract 5 ~ 15
Licorice 5 ~ 15
Phellodendron extract 3 ~ 8
Coptis extract 3 ~ 8
Baical Skullcap root P.E 3 ~ 8
Radix paeoniae alba extraction 1 ~ 5
Rhizoma Atractylodis Macrocephalae extract 1 ~ 5
Purslane extract 5 ~ 10.
Further, the preparation method of described each Chinese medical extract comprises the following steps:
After described herb powder is crossed 20 mesh sieves, it is added thereto to the water of herb powder quality 10 ~ 15 times, soaks 0.5 ~ 1h
Rear soak by water 0.5 ~ 1h, filters and leaves and takes supernatant, obtain first supernatant, the filter residue repeat the above steps being filtrated to get twice,
Obtaining secondary supernatant and three supernatants, first supernatant, secondary supernatant and three supernatants described in merging obtain always
Supernatant, described total supernatant, through concentrating, adds absolute ethyl alcohol mix and blend, filters and obtains clear liquid, by institute after removing precipitation
State the rotated evaporimeter of clear liquid be distilled off and reclaim ethanol, i.e. obtain described Chinese medical extract.
It is another object of the present invention to be achieved through the following technical solutions:
A kind of vegetable composition containing described active Chinese drug component compositions, during the raw material of described vegetable composition includes
Medicine active matter composition, water and glycerine, the ratio of weight and number of described each raw material is:
Active Chinese drug component composition 0.5 ~ 2
Water 5 ~ 10
Glycerine 3 ~ 5.
Further, the ratio of weight and number of described each raw material is:
Active Chinese drug component composition 1
Water 8
Glycerine 4.
It is another object of the present invention to be achieved through the following technical solutions:
The application of a kind of vegetable composition containing described active Chinese drug component compositions, described vegetable composition can add
In multiple cosmetics, described cosmetics include in cold cream frost/product emulsion, facial treatment essence/aquatic products and rinse-off products.
Further, when described vegetable composition is added in skin care cream/product emulsion, it is emulsified at oil phase and aqueous phase
After, it being cooled to when 50 DEG C add, the addition of described vegetable composition is 0.1 ~ 5%.
Further, when described vegetable composition is added in facial treatment essence/aquatic products, add fashionable interpolation with each component,
Finally stirring, the addition of described vegetable composition is 0.1 ~ 8%.
Further, when described vegetable composition is added in rinse-off products, each surfactant component add and
Being stirring evenly and then adding into, the addition of described vegetable composition is 0.1 ~ 10%.
The present invention provides the benefit that compared to existing technology:
1, active Chinese drug component composition physical property of the present invention is stable, is difficult to crystallization, adds it in cosmetics
Technique is simple, it is adaptable to industrial production；
2, being added to cosmetics by active Chinese drug component composition of the present invention, carry out efficacy assessments mensuration, result can
Have suppression and the effect improved to symptoms such as dry skin, rubescent, itch, eczemas, the combination of this natural plant extracts can
Apply in emulsifying cream or emulsion, it is also possible to be added on all kinds of surfactant, elite, in the care product such as products such as wet tissue,
Play moisturizing, anti-effect such as quick, anti-inflammatory and reparation.
Accompanying drawing explanation
Fig. 1 is subjects skin's moisture test result figure；
Fig. 2 is subjects skin's fat content test result figure.
Detailed description of the invention
Embodiment 1
A kind of active Chinese drug component compositions, the raw material of described composition includes that shrubby sophora extract, licorice, golden cypress carry
Take thing, coptis extract, Baical Skullcap root P.E, radix paeoniae alba extraction, Rhizoma Atractylodis Macrocephalae extract, purslane extract, the weight of described each raw material
Amount portion rate is:
Shrubby sophora extract 5 ~ 15
Licorice 5 ~ 15
Phellodendron extract 3 ~ 8
Coptis extract 3 ~ 8
Baical Skullcap root P.E 3 ~ 8
Radix paeoniae alba extraction 1 ~ 5
Rhizoma Atractylodis Macrocephalae extract 1 ~ 5
Purslane extract 5 ~ 10.
Further, the preparation method of described each Chinese medical extract comprises the following steps:
After described herb powder is crossed 20 mesh sieves, it is added thereto to the water of herb powder quality 10 ~ 15 times, soaks 0.5 ~ 1h
Rear soak by water 0.5 ~ 1h, filters and leaves and takes supernatant, obtain first supernatant, the filter residue repeat the above steps being filtrated to get twice,
Obtaining secondary supernatant and three supernatants, first supernatant, secondary supernatant and three supernatants described in merging obtain always
Supernatant, described total supernatant, through being concentrated by evaporation, adds absolute ethyl alcohol mix and blend, filters and obtains clear liquid after removing precipitation,
Rotated for described clear liquid evaporimeter is distilled off and reclaims ethanol, i.e. obtains described Chinese medical extract.
Unit of weight used by the present embodiment is kilogram, it is also possible to for gram；
Each raw material described in the present embodiment is on market the conventional products sold；
In the present embodiment, each described raw material can in the ratio range be given flexible combination, at this most one by one piece
Lift.
Embodiment 2
A kind of vegetable composition containing described active Chinese drug component compositions, during the raw material of described vegetable composition includes
Medicine active matter composition, water and glycerine, the ratio of weight and number of described each raw material is:
Active Chinese drug component composition 0.5 ~ 2
Water 5 ~ 10
Glycerine 3 ~ 5.
Further, the ratio of weight and number of preferred described each raw material is:
Active Chinese drug component composition 1
Water 8
Glycerine 4.
The application of the vegetable composition containing described active Chinese drug component compositions, described vegetable composition can make an addition to many
Planting in cosmetics, described cosmetics include in cold cream frost/product emulsion, facial treatment essence/aquatic products and rinse-off products.
Further, when described vegetable composition is added in skin care cream/product emulsion, it is emulsified at oil phase and aqueous phase
After, it being cooled to when 50 DEG C add, the addition of described vegetable composition is 0.1 ~ 5%.
Further, when described vegetable composition is added in facial treatment essence/aquatic products, add fashionable interpolation with each component,
Finally stirring, the addition of described vegetable composition is 0.1 ~ 8%.
Further, when described vegetable composition is added in rinse-off products, each surfactant component add and
Being stirring evenly and then adding into, the addition of described vegetable composition is 0.1 ~ 10%.
Embodiment 3
The present embodiment is the preferred version on the basis of embodiment 1,2, and raw materials used quality is same as in Example 1, institute
The ratio of weight and number stating each raw material is:
Shrubby sophora extract 10
Licorice 8
Phellodendron extract 8
Coptis extract 5
Baical Skullcap root P.E 5
Radix paeoniae alba extraction 3
Rhizoma Atractylodis Macrocephalae extract 3
Purslane extract 5.
Embodiment 4
The present embodiment is the preferred version on the basis of embodiment 1,2, and raw materials used quality is same as in Example 1, institute
The ratio of weight and number stating each raw material is:
Shrubby sophora extract 10
Licorice 10
Phellodendron extract 5
Coptis extract 5
Baical Skullcap root P.E 5
Radix paeoniae alba extraction 3
Rhizoma Atractylodis Macrocephalae extract 3
Purslane extract 8.
Above-mentioned each raw material is mixed and obtains active Chinese drug component compositions, according to described active Chinese drug component compositions with
Water, the weight ratio of glycerine are that 1:0.8:0.4 is prepared as vegetable composition stoste, and described composition stoste can be applied through being filtrated to get
Vegetable composition in cosmetics.
The present embodiment, as a example by skin care cream series products, adds the plant described in the present embodiment in skin care cream series products
Composition, in the formula of described product, the ratio of weight and number of each raw material is as follows:
Cetostearyl alcohol 4
Stearine 3
Dimethyl silicone polymer 5
Caprylic/capric triglyceride 2
Propane diols 3
Ceteth-20 1
Lauric alcohol sodium sulfovinate 0.5
Vegetable composition 3
Carbomer sodium 0.5
Preservative 0.01 ~ 0.5
Essence 0.02 ~ 0.5
Deionized water adds to 100%.
The preparation method of described skin care cream series products comprises the following steps:
A., in oil phase pretreatment tank, accurately weigh oil phase raw material (cetostearyl alcohol, sweet according to above-mentioned ratio of weight and number
Oleostearin acid esters, dimethyl silicone polymer, caprylic/capric triglyceride) add in reactor, start agitating heating 90 DEG C ~ 100
DEG C (preferably 95 DEG C) all dissolve to material, obtain oil phase thing；
B., in aqueous phase pretreatment tank, propane diols, ceteth-20, coconut palm are accurately weighed according to above-mentioned ratio of weight and number
Oleyl sulfate sodium is put in deionized water, starts stirring, is heated to 90 DEG C ~ 100 DEG C (preferably 95 DEG C) whole to material
Dissolve, obtain aqueous-phase material；
The most filtered oil phase thing is drawn through in the emulsion tank of preheating, sucks aqueous-phase material afterwards, and startup scraper plate stirs successively
Mix, quickly stirring, homogenizer (starting emulsifying kettle quickly to stir and homogenizer about 10 ~ 12 minutes), now emulsification temperature in the kettle is not
Should be less than 85 DEG C.After carrying out vacuum emulsification, insulated and stirred is after 10 ~ 15 minutes, then starts cooling device cooling；
D., when temperature drops to 50 DEG C, described vegetable composition, essence, preservative are added according to above-mentioned ratio of weight and number,
Continue stirring, when temperature continue to drop to 30 DEG C spend time, discharging after the assay was approved.
Note: the blank sample of test is not added with vegetable composition, and remaining operation is identical.
Adding the skin care cream of described vegetable composition, have moisturizing maintenance effect, skinfeel is smooth, free from extraneous odour, after using
The barrier function of skin can be improved, for sensitiveness skin, there is repair, Long-Time Service can improve rubefaction, be dried and
The sensitiveness symptoms such as itch.
For effect of skin care cream of the detection described vegetable composition of described interpolation, carry out dermal application test, skin is repaiied
Multiple aptitude tests and crowd's test, concrete operations and result are as follows:
(1) dermal application test: choose 30 volunteers, smearing method: left and right inner forearm skin, after every day is cleaned,
Respectively smearing once, left arm smears blank sample comparison, and right arm is smeared the skin care cream containing vegetable composition, smeared 28 continuously
My god, test the 0th day respectively, the 7th day, the 14th day, the 21st day, and data when the 28th day, test event included: moisture content contains
Amount, fat content.Each test event of blank sample and testing sample surveys 3 groups of data respectively at each time point, asks it
Average.
Obtain test result:
Water content, fat content tester be: Germany CK company Multi-functional skin tester MPA580, test wrapper
Border: temperature: 20 ~ 22 DEG C, humidity: 40% ~ 60%.Appraisal result is as shown in Figure 1.
The skin care cream containing vegetable composition is smeared as seen from Figure 1 by continuous print, about tested after two weeks
Person's skin moisture content reaches range of normal value (> 45), and smear the blank sample without vegetable composition, though skin moisture has
Increase, but after increasing DeGrain, and 28 days, be also not up to normal level, belong to the scope of dry skin.
As in figure 2 it is shown, by the experiment to experimenter's fat content situation, result can be seen that subjects skin's fat content
After continuing 28 days smear, all have rising, and all reach normal oils content range (> 6), difference is, blank product
Skin oil and fat increases slowly, and continues for some time, and is not further added by, though fat content is in normal range (NR), but close to lower limit.
The subjects skin's fat content smearing the skin care cream containing vegetable composition increases substantially, uses about 10 days skin oil and fats
Content still has the trend of increase after reaching normal range (NR), and 28 days.Visible, the cosmetics of this described vegetable composition have alleviation
Scaly dry skin, reconciles skin oil-water balance and effect of moisturizing.
(2) skin repair aptitude tests
Experimental technique: choose the identical two pieces of regions of 1 volunteer (same or different) inboard arm, uses medical adhesive tape anti-
Copy/paste and tearing 10 times, produce identical two panels erythomatous lesions district (A district and B district), smear respectively at two panels damage zone after 30min
Blank product (A district) and the skin care cream (B district) containing vegetable composition, sooner or later respectively smear once, smear 7 days continuously every day.
Result shows, B district erythema (smearing the skin care cream containing vegetable composition) is after smearing for the first time, and pain subtracts
Gently, smearing lighter after 1 day, after 3 days, damage field is wholly absent；Control sample (is smeared) by A district, smears pain after 1 day
Disappearing, color is the heaviest compared with B district, and after smearing 3 days, damage field is faintly visible, and after smearing 7 days, damage field is wholly absent.
I.e. contain the skin care cream of vegetable composition to have and can promote skin repair, alleviate effect that skin is sensitive.
(3) crowd's test
Test method: choosing 60 examples and have dermatitis, itch or the volunteer of other drying property skin problems, every day is the cleanest
Use the skin care cream containing vegetable composition to smear after skin, continue 28 days, fill in use feedback opinion table.Obtained by statistical analysis
Go out conclusion as shown in table 1:
Being tested investigation from crowd, the skin care cream containing said composition can resist scaly dry skin well, has
Good moisture-keeping efficacy, has suppression for dermatitis, sensitiveness skin crowd and alleviates itch, improving dermatitis and eczema symptom etc.
Effect, has preferable skin-care effect, and popularizing application prospect is wide.
Claims (9)
1. the active Chinese drug component compositions that a kind is applied in cosmetics, it is characterised in that the raw material of described composition is by kuh-seng
Extract, licorice, phellodendron extract, coptis extract, Baical Skullcap root P.E, radix paeoniae alba extraction, Rhizoma Atractylodis Macrocephalae extract, dent
Amaranth extract forms, and the ratio of weight and number of described each raw material is:
Shrubby sophora extract 5 ~ 15
Licorice 5 ~ 15
Phellodendron extract 3 ~ 8
Coptis extract 3 ~ 8
Baical Skullcap root P.E 3 ~ 8
Radix paeoniae alba extraction 1 ~ 5
Rhizoma Atractylodis Macrocephalae extract 1 ~ 5
Purslane extract 5 ~ 10；
The preparation method of each Chinese medical extract comprises the following steps:
After herb powder is crossed 20 mesh sieves, it is added thereto to the water of herb powder quality 10 ~ 15 times, soaks soak by water after 0.5 ~ 1h
0.5 ~ 1h, filters and leaves and takes supernatant, obtain first supernatant, and the filter residue repeat the above steps being filtrated to get twice obtains secondary
Supernatant and three supernatants, first supernatant, secondary supernatant and three supernatants described in merging obtain total supernatant, institute
State total supernatant and pass through concentration, add absolute ethyl alcohol mix and blend, filter after removal precipitates and obtain clear liquid, by described clear liquid through revolving
Turn evaporimeter be distilled off and reclaim ethanol, i.e. obtain described Chinese medical extract.
The active Chinese drug component compositions being applied in cosmetics the most according to claim 1, it is characterised in that described each former
The ratio of weight and number of material is:
Shrubby sophora extract 10
Licorice 10
Phellodendron extract 5
Coptis extract 5
Baical Skullcap root P.E 5
Radix paeoniae alba extraction 3
Rhizoma Atractylodis Macrocephalae extract 3
Purslane extract 8.
The active Chinese drug component compositions being applied in cosmetics the most according to claim 1, it is characterised in that described each former
The ratio of weight and number of material is:
Shrubby sophora extract 10
Licorice 8
Phellodendron extract 8
Coptis extract 5
Baical Skullcap root P.E 5
Radix paeoniae alba extraction 3
Rhizoma Atractylodis Macrocephalae extract 3
Purslane extract 5.
4. the vegetable composition containing the active Chinese drug component compositions being applied in cosmetics as claimed in claim 1,
It is characterized in that, the raw material of described vegetable composition includes active Chinese drug component compositions, water and glycerine, the weight of described each raw material
Portion rate is:
Active Chinese drug component composition 0.5 ~ 2
Water 5 ~ 10
Glycerine 3 ~ 5.
Vegetable composition the most according to claim 4, it is characterised in that the ratio of weight and number of described each raw material is:
Active Chinese drug component composition 1
Water 8
Glycerine 4.
6. a vegetable composition as claimed in claim 4 application in preparing cosmetics, it is characterised in that described cosmetic
Product include in skin care cream/product emulsion, facial treatment essence/aquatic products and rinse-off products.
The vegetable composition the most according to claim 6 application in preparing cosmetics, it is characterised in that described plant group
When compound is added in skin care cream/product emulsion, after oil phase and aqueous phase emulsify, be cooled to when 50 DEG C add, described in plant
The addition of compositions is 0.1 ~ 5%.
The vegetable composition the most according to claim 6 application in preparing cosmetics, it is characterised in that described plant group
When compound is added in facial treatment essence/aquatic products, adds fashionable interpolation with each component, finally stir, described vegetable composition
Addition be 0.1 ~ 8%.
The vegetable composition the most according to claim 6 application in preparing cosmetics, it is characterised in that described plant group
When compound is added in rinse-off products, adds at each surfactant component and be stirring evenly and then adding into, described plant society
The addition of thing is 0.1 ~ 10%.
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| CN106244357B (en) * | 2016-08-18 | 2018-08-14 | 河南中医学院 | A kind of antiallergy Chinese medicine handmade soap |
| CN106726865A (en) * | 2016-11-11 | 2017-05-31 | 宁波亿拍客网络科技有限公司 | It is a kind of to the addition of the daily chemical product that natural medicinal ingredient is not destroyed Chinese herbal medicine |
| CN106361663A (en) * | 2016-11-27 | 2017-02-01 | 珍尔姿（广州）化妆品有限公司 | Long effect moisture preservation functional skin lotion |
| CN109549883A (en) * | 2017-09-26 | 2019-04-02 | 东莞自然衡健康科技有限公司 | A kind of plant antiallergic is releived the preparation method of agent |
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| CN108653136A (en) * | 2018-06-26 | 2018-10-16 | 戴伟 | A kind of Chinese medicine composition and its mixed extract being used for cosmetics frost breast and facial mask |
| CN109394634B (en) * | 2018-12-27 | 2021-08-13 | 陈贤 | Anti-inflammatory repair composition, preparation method and application thereof |
| CN109646374A (en) * | 2019-01-21 | 2019-04-19 | 秋臣化妆品有限公司 | A kind of herbal mildy wash and preparation method of moisturizing whitening |
| CN109718185A (en) * | 2019-03-12 | 2019-05-07 | 北温草生物科技(上海)有限公司 | One kind is releived antianaphylactic herbal composite |
| CN109984973A (en) * | 2019-05-09 | 2019-07-09 | 李媛媛 | A kind of acne-eliminating cosmetic and preparation method thereof containing compound plant extract |
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| CN114869818B (en) * | 2022-05-13 | 2023-06-20 | 妙梵医药科技(广州)有限公司 | Composition with repairing effect and preparation method thereof |
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