CN104145023B - 用于酶稳定化的相容性溶质四氢嘧啶及其衍生物 - Google Patents

用于酶稳定化的相容性溶质四氢嘧啶及其衍生物 Download PDF

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Publication number
CN104145023B
CN104145023B CN201380012775.4A CN201380012775A CN104145023B CN 104145023 B CN104145023 B CN 104145023B CN 201380012775 A CN201380012775 A CN 201380012775A CN 104145023 B CN104145023 B CN 104145023B
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composition
layer
solvent
components
ectoine
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Expired - Fee Related
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CN201380012775.4A
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English (en)
Chinese (zh)
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CN104145023A (zh
Inventor
G.开姆尼蒂厄斯
O.加
T.纳格尔
K.雷赫特
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CN201380012775.4A 2012-03-06 2013-03-05 用于酶稳定化的相容性溶质四氢嘧啶及其衍生物 Expired - Fee Related CN104145023B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12158286.0A EP2636750A1 (en) 2012-03-06 2012-03-06 Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
EP12158286.0 2012-03-06
PCT/EP2013/054351 WO2013131885A1 (en) 2012-03-06 2013-03-05 Compatible solute ectoine as well as derivatives thereof for enzyme stabilization

Publications (2)

Publication Number Publication Date
CN104145023A CN104145023A (zh) 2014-11-12
CN104145023B true CN104145023B (zh) 2016-11-09

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CN201380012775.4A Expired - Fee Related CN104145023B (zh) 2012-03-06 2013-03-05 用于酶稳定化的相容性溶质四氢嘧啶及其衍生物

Country Status (9)

Country Link
US (1) US20140363835A1 (enExample)
EP (2) EP2636750A1 (enExample)
JP (1) JP6022609B2 (enExample)
KR (1) KR101707292B1 (enExample)
CN (1) CN104145023B (enExample)
CA (1) CA2861054A1 (enExample)
ES (1) ES2606862T3 (enExample)
PL (1) PL2823052T3 (enExample)
WO (1) WO2013131885A1 (enExample)

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CN106232830B (zh) * 2014-04-18 2020-02-14 株式会社同仁化学研究所 脱氢酶及其基质浓度的测定方法，电子中介和包含该电子中介的脱氢酶及其基质用测定试剂
KR20160063912A (ko) * 2014-11-27 2016-06-07 삼성에스디아이 주식회사 양극 활물질, 이를 채용한 리튬 전지, 및 상기 양극 활물질의 제조방법
CN105136874B (zh) * 2015-06-05 2018-01-26 北京乐普医疗科技有限责任公司 一种酶生物传感器中的检测配方
WO2018067235A1 (en) 2016-10-05 2018-04-12 Roche Diabetes Care, Inc. Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same
US11808708B2 (en) 2020-08-12 2023-11-07 F.A.T. Stats LLC Method for maintaining the health of a diabetic patient by preventing the occurrence of diabetic ketoacidosis
KR102513450B1 (ko) 2021-01-07 2023-03-22 한국생명공학연구원 신규한 엑토인 합성효소 및 그 용도
CN114277012B (zh) * 2021-12-31 2024-02-23 华熙生物科技股份有限公司 一种糖胺聚糖合成酶的冻干保护剂及其应用

Citations (1)

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CN101801985A (zh) * 2007-06-19 2010-08-11 霍夫曼-拉罗奇有限公司 氧化还原介体

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DE4244580A1 (de) 1992-12-31 1994-07-07 Galinski Erwin A Verfahren zur in vivo Gewinnung von Inhaltsstoffen aus Zellen
DE4311464A1 (de) 1993-04-08 1994-10-13 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen Bestimmung eines Analyten mit einer PQQ-abhängigen Dehydrogenase
DE19629656A1 (de) 1996-07-23 1998-01-29 Boehringer Mannheim Gmbh Diagnostischer Testträger mit mehrschichtigem Testfeld und Verfahren zur Bestimmung von Analyt mit dessen Hilfe
DE19639169A1 (de) 1996-09-24 1998-04-02 Boehringer Mannheim Gmbh Redoxaktive Verbindungen und deren Anwendung
DE19753850A1 (de) 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Probennahmevorrichtung
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US5902731A (en) * 1998-09-28 1999-05-11 Lifescan, Inc. Diagnostics based on tetrazolium compounds
AU2002215966B2 (en) 2000-10-27 2006-05-04 F. Hoffmann-La Roche Ag Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase
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US20060099567A1 (en) * 2004-04-08 2006-05-11 Biomatrica, Inc. Integration of sample storage and sample management for life science
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Also Published As

Publication number Publication date
EP2823052A1 (en) 2015-01-14
KR20140132394A (ko) 2014-11-17
JP2015511820A (ja) 2015-04-23
ES2606862T3 (es) 2017-03-28
EP2823052B1 (en) 2016-10-26
WO2013131885A1 (en) 2013-09-12
US20140363835A1 (en) 2014-12-11
CN104145023A (zh) 2014-11-12
KR101707292B1 (ko) 2017-02-15
HK1199071A1 (en) 2015-06-19
PL2823052T3 (pl) 2017-05-31
EP2636750A1 (en) 2013-09-11
JP6022609B2 (ja) 2016-11-09
CA2861054A1 (en) 2013-09-12

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