KR101707292B1 - 효소 안정화를 위한 상용성 용질 엑토인 및 그의 유도체 - Google Patents

효소 안정화를 위한 상용성 용질 엑토인 및 그의 유도체 Download PDF

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KR101707292B1
KR101707292B1 KR1020147027823A KR20147027823A KR101707292B1 KR 101707292 B1 KR101707292 B1 KR 101707292B1 KR 1020147027823 A KR1020147027823 A KR 1020147027823A KR 20147027823 A KR20147027823 A KR 20147027823A KR 101707292 B1 KR101707292 B1 KR 101707292B1
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KR20140132394A (ko
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가브리엘레 헴니티우스
오토 가
토마스 나겔
칼 레히트
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에프. 호프만-라 로슈 아게
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020147027823A 2012-03-06 2013-03-05 효소 안정화를 위한 상용성 용질 엑토인 및 그의 유도체 Expired - Fee Related KR101707292B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12158286.0A EP2636750A1 (en) 2012-03-06 2012-03-06 Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
EP12158286.0 2012-03-06
PCT/EP2013/054351 WO2013131885A1 (en) 2012-03-06 2013-03-05 Compatible solute ectoine as well as derivatives thereof for enzyme stabilization

Publications (2)

Publication Number Publication Date
KR20140132394A KR20140132394A (ko) 2014-11-17
KR101707292B1 true KR101707292B1 (ko) 2017-02-15

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KR1020147027823A Expired - Fee Related KR101707292B1 (ko) 2012-03-06 2013-03-05 효소 안정화를 위한 상용성 용질 엑토인 및 그의 유도체

Country Status (9)

Country Link
US (1) US20140363835A1 (enExample)
EP (2) EP2636750A1 (enExample)
JP (1) JP6022609B2 (enExample)
KR (1) KR101707292B1 (enExample)
CN (1) CN104145023B (enExample)
CA (1) CA2861054A1 (enExample)
ES (1) ES2606862T3 (enExample)
PL (1) PL2823052T3 (enExample)
WO (1) WO2013131885A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220099844A (ko) 2021-01-07 2022-07-14 한국생명공학연구원 신규한 엑토인 합성효소 및 그 용도

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Publication number Priority date Publication date Assignee Title
CN106232830B (zh) * 2014-04-18 2020-02-14 株式会社同仁化学研究所 脱氢酶及其基质浓度的测定方法，电子中介和包含该电子中介的脱氢酶及其基质用测定试剂
KR20160063912A (ko) * 2014-11-27 2016-06-07 삼성에스디아이 주식회사 양극 활물질, 이를 채용한 리튬 전지, 및 상기 양극 활물질의 제조방법
CN105136874B (zh) * 2015-06-05 2018-01-26 北京乐普医疗科技有限责任公司 一种酶生物传感器中的检测配方
WO2018067235A1 (en) 2016-10-05 2018-04-12 Roche Diabetes Care, Inc. Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same
US11808708B2 (en) 2020-08-12 2023-11-07 F.A.T. Stats LLC Method for maintaining the health of a diabetic patient by preventing the occurrence of diabetic ketoacidosis
CN114277012B (zh) * 2021-12-31 2024-02-23 华熙生物科技股份有限公司 一种糖胺聚糖合成酶的冻干保护剂及其应用

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US20110143416A1 (en) * 2008-02-19 2011-06-16 Carina Horn Stabilization of dehydrogenases with stable coenzymes

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ES2145054T3 (es) 1992-07-02 2000-07-01 Roche Diagnostics Corp Un reactivo estabilizado por sales de metal bivalente.
DE4244580A1 (de) 1992-12-31 1994-07-07 Galinski Erwin A Verfahren zur in vivo Gewinnung von Inhaltsstoffen aus Zellen
DE4311464A1 (de) 1993-04-08 1994-10-13 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen Bestimmung eines Analyten mit einer PQQ-abhängigen Dehydrogenase
DE19629656A1 (de) 1996-07-23 1998-01-29 Boehringer Mannheim Gmbh Diagnostischer Testträger mit mehrschichtigem Testfeld und Verfahren zur Bestimmung von Analyt mit dessen Hilfe
DE19639169A1 (de) 1996-09-24 1998-04-02 Boehringer Mannheim Gmbh Redoxaktive Verbindungen und deren Anwendung
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AU2002215966B2 (en) 2000-10-27 2006-05-04 F. Hoffmann-La Roche Ag Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220099844A (ko) 2021-01-07 2022-07-14 한국생명공학연구원 신규한 엑토인 합성효소 및 그 용도

Also Published As

Publication number Publication date
EP2823052A1 (en) 2015-01-14
KR20140132394A (ko) 2014-11-17
JP2015511820A (ja) 2015-04-23
ES2606862T3 (es) 2017-03-28
EP2823052B1 (en) 2016-10-26
WO2013131885A1 (en) 2013-09-12
CN104145023B (zh) 2016-11-09
US20140363835A1 (en) 2014-12-11
CN104145023A (zh) 2014-11-12
HK1199071A1 (en) 2015-06-19
PL2823052T3 (pl) 2017-05-31
EP2636750A1 (en) 2013-09-11
JP6022609B2 (ja) 2016-11-09
CA2861054A1 (en) 2013-09-12

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