CN103750059A - Traditional Chinese medicine additive and feed for treating pig constipation and preparation method of traditional Chinese medicine additive and feed - Google Patents

Traditional Chinese medicine additive and feed for treating pig constipation and preparation method of traditional Chinese medicine additive and feed Download PDF

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CN103750059A
CN103750059A CN201410039032.2A CN201410039032A CN103750059A CN 103750059 A CN103750059 A CN 103750059A CN 201410039032 A CN201410039032 A CN 201410039032A CN 103750059 A CN103750059 A CN 103750059A
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weight portion
feed
chinese medicine
medicine additive
weight
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CN103750059B (en
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李佃场
黄河
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Weifang new hope six and feed Technology Co., Ltd.
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Shandong New Hope Liuhe Group Co Ltd
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Abstract

The invention provides a feed for treating pig constipation. The feed comprises a feed carrier, a feed adhesive, a nutrition supplement agent and traditional Chinese medicine additives, wherein the traditional Chinese medicine additives comprise barbados aloe, root of rehmannia, fringed iris herb, folium sennae, fructus cannabis, semen sesami, rhizoma anemarrhenae, rhizoma phragmitis, immature bitter orange, elecampane, liquorice, codonopsis pilosula, astragalus membranaceus and dates. The feed with the traditional Chinese medicine additives has the advantages of high efficiency, small toxic and side effects, freedom of residue, no drug resistance, no environment pollution, short curative course and rapid action when being used for treating constipation of pigs.

Description

The Chinese medicine additive, feed and the preparation method that are used for the treatment of pig constipation
Technical field
The present invention relates to animal foodstuff technical field, relate in particular to a kind of Chinese medicine additive, feed and preparation method who is used for the treatment of pig constipation that comprise.
Background technology
Pig constipation: constipation is to be stagnated and failed in enteron aisle to discharge in time by intestinal contents, the hardening that becomes dry gradually causes intestinal tube part to increase gradually, and final enteron aisle is completely constipated, is a kind of common disease.Mostly occur at colon.
The cause of disease: long-term feeding to thick and stiff feed, as the chaff of rice husk mill, accounts for the large percentage of daily ration.Feed dry feeding (particularly meticulous feed) or heat, moisture evaporation is many, and does not drink water in time or subimbition.During feed formulation, lack cobalt blue pigment or coarse fodder, intestines wall lacks coarse-fibred stimulation and affects enterocinesia, adds hypomotility.Farrowing overlong time.Stocking density is excessive, and some have caloric disease secondary.Symptom: general body temperature does not raise, anorexia or absolutely useless, arranges a small amount of argol or does not discharge feces.Weak or the just good sleeping and action of being reluctant subsequently of melting out of enterocinesia, presses postabdomen and can contact rigid piece, sometimes refers to examine rectum and can contact excrement piece.Along with the prolongation of the course of disease, conjunctival congestion, the minimizing of urinating, look xanthochromia are thick, and rectal mucosa is congested, dry.Also there is looking back the colic symptoms of belly, even groan.Palpation belly is responsive.Incomplete obstruction still can be arranged a small amount of excrement.Sick just anorexia, belly expand, normal performance defecation shape, but stagnant slow, the thirsty and normal drinking-water of discharging feces.Sick pig performance is slight uneasy, sends rumble cry, and with hand, pressing belly has pain reaction.Along with the development of the state of an illness, appetite disappears, and lassitude is thirsty, and drinking times increases, and conjunctival congestion is enriched.The veutro of the thin sick pig of hand body, can enrich solid excrement piece by touching in large intestine, sometimes occurs slight colic symptoms.As be former, general body temperature is normal.Sometimes due to the excrement piece compressing bladder in colon, the renal shutdown that can occur together symptom diagnostic point: body temperature is not high, anorexia or absolutely useless, intestines sound is weak or disappear, defecation is discharged feces less or not, often exerts duty, has stomachache, stomach wall touch-sensitive, has excrement piece, sometimes refers to examine rectum and can touch excrement piece.
Owing to still not having desirable medicine to be used for the treatment of this disease at present, utilizing chemical synthetic drug control is the major measure that Present Domestic is taked outward, many medicine cathartics etc. are all widely used, and use cathartic chemical synthetic drug to treat, there is in the early stage certain prevention effect, but along with the generally use of these medicines, also make this disease more and more be difficult to control and treatment.Meanwhile, along with a large amount of uses of these medicines, residual drug toxicity in a large number in animal body, when edible these porks of people, the mankind's life and health in serious threat.
The side effect of Western medicine is larger, and, Western medicine only has obvious curative effect to single illness or a class illness when treatment, for the more disease of some illnesss, curative effect may be just not too obvious, usually need out a lot of Western medicine, and, Western medicine synthesizes, price is conceived to integral body in the time of naturally can be than a lot of China of Chinese herbal medicine and Chinese patent drug costliness traditional traditional Chinese medicine application, emphasize to regulate allomeric function, improve the premunition of body self, prolonged application is safe and reliable, therefore, aspect treatment pig constipation, playing more and more important effect because have drawn from nature, and, there is hypertoxic herbal medicine few, and use clinically and compare standard, therefore Chinese herbal medicine can be more safer than Chinese patent drug and Western medicine, the side effect of Chinese herbal medicine is in this three minimum by comparison time.
Summary of the invention
Technical problem to be solved by this invention is feed of the Chinese medicine additive that is to provide a kind of novel containing to be used for the treatment of pig constipation and preparation method thereof, the Chinese medicine additive of employing to pig constipation treatment have efficient, toxic and side effect is little, noresidue, do not develop immunity to drugs, free from environmental pollution, can increase Abwehrkraft des Koepers, short treating period, effect rapid, cheap, have and the advantage such as apply.
In order to address the above problem, the invention provides a kind of feed that is used for the treatment of pig constipation, comprise: feed vector, feed adhesive, nutritious supplementary pharmaceutical and Chinese medicine additive, described Chinese medicine additive comprises: aloe, the dried rhizome of rehmannia, fringed iris herb, folium sennae, fructus cannabis, flax benevolence, the wind-weed, reed rhizome, the dried immature fruit of citron orange, the banksia rose, Radix Glycyrrhizae, Radix Codonopsis, the Radix Astragali and date.
In described Chinese medicine additive, the ratio of weight and number of various components is: aloe 14-35 weight portion, dried rhizome of rehmannia 10-35 weight portion, fringed iris herb 10-35 weight portion, folium sennae 15-30 weight portion, fructus cannabis 20-35 weight portion, flax benevolence 10-25 weight portion, wind-weed 15-34 weight portion, reed rhizome 10-20 weight portion, dried immature fruit of citron orange 15-30 weight portion, banksia rose 14-32 weight portion, Radix Glycyrrhizae 15-30 weight portion, Radix Codonopsis 10-20 weight portion, Radix Astragali 10-30 weight portion and date 15-25 weight portion.
In described Chinese medicine additive, the ratio of weight and number of various components is: aloe 20-35 weight portion, dried rhizome of rehmannia 15-35 weight portion, fringed iris herb 20-35 weight portion, folium sennae 15-20 weight portion, fructus cannabis 15-35 weight portion, flax benevolence 15-25 weight portion, wind-weed 15-30 weight portion, reed rhizome 10-15 weight portion, dried immature fruit of citron orange 20-30 weight portion, banksia rose 20-32 weight portion, Radix Glycyrrhizae 20-30 weight portion, Radix Codonopsis 15-20 weight portion, Radix Astragali 10-20 weight portion and date 15-20 weight portion.
With respect to 100 weight portion feed vectors, the addition of described feed adhesive is 10~20 weight portions, and the addition of described nutritious supplementary pharmaceutical can be 2~6 weight portions, and the addition of described Chinese medicine additive is 4~8 weight portions.
Described nutritious supplementary pharmaceutical is one or more in amino acid, vitamin, mineral trace element and enzyme preparation; Described feed adhesive is Strong flour and starch, and the weight fraction ratio of described Strong flour and described starch is: 2-3:1-2.
In order better to realize foregoing invention object, the invention provides a kind of preparation method of feed, described preparation method comprises:
The first step, drops in proportion mixer by each component of described Chinese medicine additive and stirs 20-50 minute, fully mixes; The mixture of acquisition is poured into and in pulverizer, pulverized and sieve, through the screening of 100-300 object, obtain Chinese medicine additive powder fine powder;
Second step, each component of getting in feed adhesive is mixed, and adds water to start modified, and refining temperature is 60-70 ℃, the dry feed adhesive that obtains after stirring, with respect to the feed adhesive of 100 weight portions, the addition of described water is 20-30 weight portion;
The 3rd step, by described corn, wheat, soybean, wheat bran and Chinese sorghum, one or more are pulverized after mixing, and grinding particle size is 400~600mm, obtains feed vector;
The 4th step; the feed adhesive that the Chinese medicine additive powder that the first step is obtained, second step obtain; the feed vector that the 3rd step obtains and nourishing additive agent mix; putting into multiplex mixer stirs 120 minutes~150 minutes; after taking-up, put into ring mode bulking machine expanded; control the temperature of bulking machine between 80 ℃~90 ℃; the expanded time is 1~2 hour; the aridity of controlling material to be extruded is 90%~95%; after taking-up, proceed in ring mode grit machine and be produced into and precipitate hard particles feed; then use 50 order ~ 100 meshes to sieve, obtain described feed.
The present invention also provides a kind of Chinese medicine additive that is used for the treatment of pig constipation, and in described Chinese medicine additive, the ratio of weight and number of various components is: aloe 14-35 weight portion, dried rhizome of rehmannia 10-35 weight portion, fringed iris herb 10-35 weight portion, folium sennae 15-30 weight portion, fructus cannabis 20-35 weight portion, flax benevolence 10-25 weight portion, wind-weed 15-34 weight portion, reed rhizome 10-20 weight portion, dried immature fruit of citron orange 15-30 weight portion, banksia rose 14-32 weight portion, Radix Glycyrrhizae 15-30 weight portion, Radix Codonopsis 10-20 weight portion, Radix Astragali 10-30 weight portion and date 15-25 weight portion.
The preparation method of described Chinese medicine additive comprises:
The first step, drops in proportion mixer by each component of described Chinese medicine additive and stirs 20-50 minute, fully mixes;
Second step, the mixture that the first step is obtained is poured into and in pulverizer, is pulverized and sieve, through the screening of 100-300 object, acquisition Chinese medicine additive powder fine powder.
Beneficial effect of the present invention: the feed that the present invention contains Chinese medicine additive, has efficiently suffering from the treatment of constipation pig, toxic and side effect is little, noresidue, do not develop immunity to drugs, free from environmental pollution, short treating period, act on advantage rapidly.
The specific embodiment
Chinese veterinarian thinks, thinks that the normal physiological function of large intestine is excreting foodstuff instead of storing essence.The stimulation of rectal contents to rectal wall perceptron is the startup factor that causes defecation reflex.Ight soil enters rectum and enters stomach, through gastro-intestinal digestion, absorbs, and last waste matter, is transmitted by large intestine.Under normal circumstances, the poised state in " yin and yang in equilibrium ", digestion excretion is normal, and once imbalance of yin and yang, fever and chills are unbalance, and actual situation is bigoted, and here raw constipation is.Phlegm stagnancy, large intestine transmission is unfavorable, is " yin constipation "; Large intestine Tianjin consumption be spleen fortune unable and just hard person send out as " spleen approximately ", " spleen is approximately " refers to that insufficiency of the spleen Tianjin is few, intestinal juice is dry, so that the illness that goes out of the hard difficulty of defecating, and controls to take numb benevolence ball (numb benevolence ball is hemp seed soft capsule through modern preparation process improvement).Large intestine is agitated unable, be kidney yang lose in warm and just puckery person send out as " deficiency of yang is secret "; Deficiency of blood Tianjin is withered, and ight soil loses to moisten and is " hematasthenic constipation "; Stomach energy as bright in sun is crossed Sheng, the bright body fluid of heat, and liquid consumption is hindered in Tianjin, and enteron aisle loses in making moist and causes " heat is secret "; If deficiency of spleen-QI, elevate a turnable ladder is not normal, collapse from qi deficiency, and large intestine transmission is unable and cause " empty secret "; Liver controlling conveyance and dispersion bar reaches, if stagnation of liver qi, depression and stagnation of QI, the defeated cloth of body fluid is not normal, sends out as " gas is secret " etc.Treat eventful clearing away heat and loosing the bowels, enriching yin defaecation, regulating qi to loosen the bowels.
Therefore select this prescription: it is primary treatment principle treatment pig constipation that aloe, the dried rhizome of rehmannia, fringed iris herb, folium sennae, fructus cannabis, flax benevolence, the wind-weed, reed rhizome, the dried immature fruit of citron orange, the banksia rose, Radix Glycyrrhizae, Radix Codonopsis, the Radix Astragali, Chinese yam, date take that leading to bows and expel the heat-evil removing toxic substances, relieving constipation by purgation.In side, aloe, the dried rhizome of rehmannia, fringed iris herb, logical the bowing of folium sennae expel the heat-evil, fructus cannabis, flax benevolence relaxes bowel, and the wind-weed, reed rhizome promote the production of body fluid and moisturize, the dried immature fruit of citron orange, banksia rose regulating the qi flowing in the channels, aloe defaecation, the Radix Astragali is anti-rush down under too to hinder healthy tendency, the dried rhizome of rehmannia, Radix Codonopsis, the tuber of dwarf lilyturf, Radix Glycyrrhizae, date coordinating the drug actions of a prescription, the mitigation property of medicine, in case dredged down too with nourishing Yin and promoting production of body fluid.
Each component pharmacology is as follows:
Aloe: under rushing down; Clearing liver; Desinsection.Main constipation with heat retention; Irascibility headache; Hot eyes infantile convulsion; Abdominal pain due to enterositosis; Mange; Hemorrhoid complicated by anal fistula; Solution crotons poison.For constipation, infantile malnutrition, infantile convulsion; Control wet tinea outward.1. < < property of medicine opinion > >: kill children's's infantile malnutrition due to digestive disturbances or intestinalparasites ascarid.Brain infantile malnutrition due to digestive disturbances or intestinalparasites is killed in main nasal insufflation, except rhiocnesmus.2. < < Haiyao Bencao, Oversea Materia Medica > >: all infantile malnutrition due to digestive disturbances or intestinalparasites heat of main children's.3. < < Kaibao Bencao > >: main hot blast is unhappy, hot gas between chest diaphragm, improving eyesight relieving palpitation, children epilepsy infantile convulsion, treats five infantile malnutrition due to digestive disturbances or intestinalparasites, kills the sick sore fistula of three worms and hemorrhoid.Solution crotons poison.4. < < Bencao Tujing > >: controlling wet itching, that scratches has a yellow juice person; Control again the tooth of hideing.5. < < must join herbal > >: loose scrofula, control frightened epilepsy, and Li Shui is except swollen.6. < < book on Chinese herbal medicine new > > again: control irascibility, town liver wind, the heat that clears away heart-fire, separates vexedly, slakes thirst and help produce saliva, hearing-improing and eyesight improving, the tooth that disappears is swollen, separates fire poison.
The dried rhizome of rehmannia: there is clearing heat and cooling blood effect, for warm heat disease heat, enter ying blood, high fever coma, dry tongue is deep red.As qingying decoction.Can be used for controlling warm heat disease heat and enter ying blood, blood-head poison is contained, hematemesis and epistaxis, and macula purple is black.Nourishing Yin and promoting production of body fluid effect is thirsty for Tianjin wound, and interior heat is quenched one's thirst.Control warm disease impairment of yin, the dry constipation of intestines, as Zengye Tang.Fresh dried rhizome of rehmannia sweet-bitter flavor Great Cold, acts on similarly to dried rehamnnia root, and the power of enriching yin is slightly inferior, but clearing heat and promoting fluid, the power of cooling blood and hemostasis is stronger.
Fringed iris herb: hardship, cold.Can relieving constipation by purgation, removing toxic substances.1. for constipation.This product has relieving constipation by purgation effect, and treatment constipation can single application.2. for hepatitis hypochondriac pain.This product has detoxication, often coordinates clinically at present the medicine such as hypericum japonicum, stringy stonecrop, Japanese ardisia treatment hepatitis hypochondriac pain, or the disease such as liver enlargement.
Folium sennae: different name senna, rush down the leaflet that leaf, soaked bamboo leaf source is the narrow leaf cassia angustifolia of legume or cassia acutifolia Delile.Sweet, bitter, Great Cold.Enter large intestine channel.Can purging heat, it is stagnant to lead.This product bitter cold in nature, matter is glutinous and lubricate, and can enter that large intestine channel rushes down accumulated heat and ease constipation is dry, therefore can be used for constipation with heat retention.
Fructus cannabis: moisturize laxation defaecation.For blood deficiency and depleted fluid, the dry constipation of intestines.< < herbal classic > >: tonifying middle-Jiao and Qi.< < does not record > >: main apoplexy sweating, relieve oedema or abdominal distension through diuresis or purgation, diuresis, broken hematocele, multiple blood vessels, newborn woman's postpartum remaining disease.< < property of medicine opinion > >: control the puckery and hot pouring of large intestine wind-heat knot.
Flax benevolence: sweet, flat.Enter lung, spleen, liver, kidney channel.Can moisturize laxation, nourishing the liver and kidney.This product has the effect relaxing bowel, and controls the withered constipation in Tianjin, can apply separately, also can with the fit applications such as Semen Juglandis, honey.This product is sweet flat, has the effect of nourishing the liver and kidney.
The wind-weed: belong to gunpowder under heat-clearing, bitter, sweet, cold.Return lung, stomach, kidney channel.Cure mainly: warm heat disease, high hot polydipsia, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, the stranguria with turbid discharge of quenching one's thirst.Can let out clearly the fire of lung stomach, the moon that again can nourishing the lung and kidney, therefore should quench one's thirst for the deficiency of Yin.Experiment in vitro shows: wind-weed decoction has stronger inhibitory action to staphylococcus, typhoid bacillus, and shigella dysenteriae, paratyphosum Bacterium, Escherichia coli, hay bacillus, comma bacillus, proteus, corynebacterium diphtheriae, Diplococcus pneumopniae, beta hemolytic streptococcus, Candida albicans etc. are also had to inhibitory action in various degree.
Reed rhizome: nature and flavor: sweet, cold.Gui Jing: return lung channel, stomach warp.Function: clearing heat and promoting fluid, relieving restlessness, preventing or arresting vomiting, diuresis.Cure mainly: for pyreticosis polydipsia, gastropyretic vomiting, cough with lung heat, lung carbuncle pyemesis, heat, drench puckery pain.Reed rhizome is for gastropyretic vomiting.Reed rhizome can clearing heat to ease the stomach preventing or arresting vomiting, does not grow again the greasy stomach that hinders, therefore the key medicine of vomitting the sound of vomiting for controlling stomach energy.
The dried immature fruit of citron orange: " dried immature fruit of citron orange is specially let out stomach excess, convinces hard knot by patient analysis, therefore the main middle part of gastric cavity, to control blood system, is treated the interventral reality of navel full, dissolving phlegm addiction, dispels and cut off the water, by place food, broken accumulation of pathogens in chest, defaecation is closed, non-this can not be also.If skin pruritus, because of hematocele stagnant in, can not nutrition flesh table, if diet do not think, can not transporting because of spleen pent-up, all get power that its pungent loose hardship rushes down also.For the gas medicine in blood system, only this claims." stop in stagnant; The full distending pain of ruffian; Constipation; After rushing down dysentery, weigh; Accumulation of pathogens in chest; Gastroptosis; The prolapse of uterus; Prolapse of the anus.
The banksia rose: promoting qi circulation and relieving pain; In tune, lead stagnant.Main born of the same parents coerce turgor foot; Abdominal distention; Tell and have loose bowels; Heavy after dysentery.For chest gastral cavity distending pain, rush down heavy after dysentery, dyspepsia does not disappear, do not feel like eating.1. the abdominal fullness and distention of the taste stagnation of the circulation of vital energy or pain, belch, n and V.2. the abdominal distension uncomfortable in chest of turbi damp obstructing in middle-JIAO, indigestion and loss of appetite loose stool.3. phlegm wets and stops up the cough and asthma of lung.4. perverse trend, wards off malicious epidemic disease temperature ghost, strong will, and main pouring is revealed.Taking for a long time not dream awake black mole sleeps.(< < herbal classic > >) 5. sterilizes, and kills terrible smart thing, a kind of malaria disease due to noxious agents produced by various parasites, and the bad unsaturated vapor of gas, partially cold in flesh, the essence of priming.
Radix Glycyrrhizae: the Qi-tonifying drug in tonic (also claiming qi-restoratives medicine).Raw Radix Glycyrrhizae can be clearing heat and detoxicating, moistens the lung and relieve the cough, and coordinating the drug actions of a prescription; Honey-fried licorice root can be invigorated the spleen and benefited qi, and quantity is especially big, and export volume is large.Except medicinal, on food, also with Radix Glycyrrhizae, cook cake additive in a large number, its sugariness is hundred times of sucrose.The a large amount of import Radix Glycyrrhizaes of western countries, therefrom extract enoxolone, control AIDS.There is anti-inflammatory, antiviral, and protecting liver and detoxication and strengthen the effects such as immunologic function.Because glycyrrhizic acid has the pharmacological action of glucocorticoid sample, without serious adverse reaction, be clinically widely used in treating various acute, chronic hepatitis, bronchitis and AIDS, also there is the functions such as anti-cancer and cancer-preventing, interferon inducers and cell immunomodulator.Glycyrrhizic acid has reducing blood lipid and study of anti-atherogenic effect, stops atherosclerotic formation.
Radix Codonopsis: be the general designation of plant Radix Codonopsis and Chinese medicine.Radix Codonopsis has tonifying middle-Jiao and Qi, the effect of invigorating the spleen benefit lung.Modern study, Radix Codonopsis, containing various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, saponin and Alkaloid, has immunity, hemangiectasis, the step-down of enhancing, improves microcirculation, strengthens the effects such as hematopoiesis function.In addition leucocyte chemotherapy radiotherapy being caused declines castering action.Herbaceos perennial, can treat disease, in Compendium of Materia Medica, records to some extent.Have a delicate constitution, insufficiency of vital energy and blood, sallow complexion, and postpartum weakness person should eat after being ill; Deficiency of spleen-QI and stomach-QI, tired, limbs fatigue, anorexia and loose stool, chronic diarrhea, insufficiency of lung-QI,deficiency of lung-QI, cough shortness of breath, deficiency of vital energy and physically weak, is easy to flu; Qi and blood deficiency person should eat; Chronic nephritis albuminuria person should eat; Chronic anaemia, chlorosis, leukaemia, thrombocytopenic purpura and rickets patient should eat.
The Radix Astragali: nature and flavor: sweet, tepor.Gui Jing: return lung, spleen, liver, kidney channel.Syndrome of deficiency of spleen qi, weak burnout, has loose bowels, the sinking of qi of middle-jiao, internal organs prolapsus, the few indigestion and loss of appetite all diseases of food.Normal and ginseng or Radix Codonopsis, the bighead atractylodes rhizome, Poria cocos, the compatibilities such as Chinese yam are treated splenasthenic diarrhea.Principle: the spleen being in charge of dampness, insufficiency of the spleen can not transporation of body fluid in lung, so dampness blocking in middle-JIAO, characteristic of dampness being descending, so the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is subject to wet and loose stool.Insufficiency of the spleenly be difficult to help the strong fortune of stomach, so food is few indigestion and loss of appetite, difficultly think diet.It is lunar that this medicine enters brothers, so excess syndrome of the lung can regulating fluid apssage, loose essence is to flesh table.Excessive splenoqi can the cloudy essence of transporting be gone up defeated in lung.
Date: have another name called red date, dry jujube, Chinese date, originate from China, in the China's plantation of existing more than 8,000 year history, be just listed in since ancient times one of " five fruits " (chestnut, peach, Lee, apricot, jujube).Red date is rich in the nutritional labelings such as protein, fat, carbohydrate, carrotene, B family vitamin, vitamin C, citrin and calcium, phosphorus, iron and CAMP.Wherein ascorbic content comes out at the top in fruit, has vitamin king's laudatory title.The CAMP that red date is contained, is the essential composition of human body cell energetic supersession, can strengthen muscular strength, eliminates fatigue, hemangiectasis, increase myocardial contractive power, improve myocardial nutrition, to preventing and treating disease of cardiovascular system, has good effect; Traditional Chinese medicine theory thinks, red date has the effects such as qi-restoratives benefit gas, nourishing blood and tranquilization, strengthening the spleen and stomach, and red date has good therapeutic effect to illnesss such as chronic hepatitis, cirrhosis, anaemia, anaphylactoid purpuras; Red date contains triterpene compound and CAMP, has stronger anticancer, anti-allergic effects.Date can moisten cardiopulmonary, cough-relieving, tonifying five zang organs, it is deficient to control, except stomach addiction gas, in can also pacifying, support spleen, flat stomach Qi, logical nine orifices, help 12 through etc.
The invention provides a kind of contain be used for the treatment of pig constipation feed, wherein, comprise: feed vector, feed adhesive, nutritious supplementary pharmaceutical and Chinese medicine additive, described Chinese medicine additive comprises: aloe, the dried rhizome of rehmannia, fringed iris herb, folium sennae, fructus cannabis, flax benevolence, the wind-weed, reed rhizome, the dried immature fruit of citron orange, the banksia rose, Radix Glycyrrhizae, Radix Codonopsis, the Radix Astragali and date.
Wherein, in described Chinese medicine additive, the ratio of weight and number of various components is, aloe 14-35 weight portion, dried rhizome of rehmannia 10-35 weight portion, fringed iris herb 10-35 weight portion, folium sennae 15-30 weight portion, fructus cannabis 20-35 weight portion, flax benevolence 10-25 weight portion, wind-weed 15-34 weight portion, reed rhizome 10-20 weight portion, dried immature fruit of citron orange 15-30 weight portion, banksia rose 14-32 weight portion, Radix Glycyrrhizae 15-30 weight portion, Radix Codonopsis 10-20 weight portion, Radix Astragali 10-30 weight portion and date 15-25 weight portion.
Wherein, in described Chinese medicine additive, the ratio of weight and number of various components is, aloe 20-35 weight portion, dried rhizome of rehmannia 15-35 weight portion, fringed iris herb 20-35 weight portion, folium sennae 15-20 weight portion, fructus cannabis 15-35 weight portion, flax benevolence 15-25 weight portion, wind-weed 15-30 weight portion, reed rhizome 10-15 weight portion, dried immature fruit of citron orange 20-30 weight portion, banksia rose 20-32 weight portion, Radix Glycyrrhizae 20-30 weight portion, Radix Codonopsis 15-20 weight portion, Radix Astragali 10-20 weight portion and date 15-20 weight portion.
Wherein, with respect to 100 weight portion feed vectors, the addition of described feed adhesive is 10~20 weight portions, and the addition of described nutritious supplementary pharmaceutical can be 2~6 weight portions, and the addition of described Chinese medicine additive is 4~8 weight portions.
Wherein, described nutritious supplementary pharmaceutical comprises: one or more in amino acid, vitamin, mineral trace element and enzyme preparation; Described feed adhesive comprises Strong flour and starch, and the weight fraction ratio of described Strong flour and described starch is: 2-3:1-2.
The present invention also provides the preparation method of the feed that contains the Chinese medicine additive that is used for the treatment of pig constipation, wherein, comprising:
The first step, drops in proportion mixer by each component of described Chinese medicine additive and stirs 20-50 minute, fully mixes; The mixture of acquisition is poured into and in pulverizer, pulverized and sieve, through the screening of 100-300 object, obtain Chinese medicine additive powder fine powder;
Second step, each component of getting in feed adhesive is mixed, and adds water to start modified, and refining temperature is 60-70 ℃, the dry feed adhesive that obtains after stirring, with respect to the feed adhesive of 100 weight portions, the addition of described water is 20-30 weight portion;
The 3rd step, by described corn, wheat, soybean, wheat bran and Chinese sorghum, one or more are pulverized after mixing, and grinding particle size is 400~600mm, obtains feed vector;
The 4th step; the feed adhesive that the Chinese medicine additive powder that the first step is obtained, second step obtain; the feed vector that the 3rd step obtains and nutritious supplementary pharmaceutical mix; putting into multiplex mixer stirs 120 minutes~150 minutes; after taking-up, put into ring mode bulking machine expanded; control the temperature of bulking machine between 80 ℃~90 ℃; the expanded time is 1~2 hour; the aridity of controlling material to be extruded is 90%~95%; after taking-up, proceed in ring mode grit machine and be produced into and precipitate hard particles feed; then use 50 order ~ 100 meshes to sieve, obtain described feed.
The present invention also provides a kind of Chinese medicine additive powder that is used for the treatment of pig constipation, wherein, comprising: aloe, the dried rhizome of rehmannia, fringed iris herb, folium sennae, fructus cannabis, flax benevolence, the wind-weed, reed rhizome, the dried immature fruit of citron orange, the banksia rose, Radix Glycyrrhizae, Radix Codonopsis, the Radix Astragali and date.
The present invention also provides a kind of preparation method who is used for the treatment of the Chinese medicine additive powder of pig constipation, wherein, comprising:
The first step, drops in proportion mixer by each component of described Chinese medicine additive and stirs 20-50 minute, fully mixes;
Second step, the mixture that the first step is obtained is poured into and in pulverizer, is pulverized and sieve, through the screening of 100-300 object, acquisition Chinese medicine additive powder fine powder.
Embodiment 1 Chinese medicine additive 1
Take aloe 20g, dried rhizome of rehmannia 30g, fringed iris herb 28g, folium sennae 30g, fructus cannabis 35g, flax benevolence 25g, wind-weed 30g, reed rhizome 20g, dried immature fruit of citron orange 30g, banksia rose 32g, Radix Glycyrrhizae 30g, Radix Codonopsis 20g, Radix Astragali 30g and date 25g, drop into mixer and stir 40 minutes, fully mix; The mixture of acquisition is poured into and in pulverizer, pulverized and sieve, through 100 objects screenings, obtain Chinese medicine additive 1.
Toxicity test
Test method: the small white mouse of getting 20 identical health of vital sign is tested, 20 small white mouses are divided into four groups, and 2 2g/ of 1, the first group of feeding of Chinese medicine additive that respectively 5 small white mouses of every group carried out to the feeding embodiment of the present invention 1 only, second group of feeding 2 multiple dose, the 3rd group of feeding 3 multiple doses, 4 groups of feeding 4 multiple doses, then observe each group, by the observation after 24 hours, 20 small white mouses are still healthy, and its activity, diet, hair, excreta are no abnormal, have no toxic reaction.Toxicity test demonstration, the Chinese medicine additive 1 of the embodiment of the present invention 1 does not have toxic action and bad reaction, clinical use safety.
Embodiment 2 feeds 1
The first step, take aloe 35g, dried rhizome of rehmannia 30g, fringed iris herb 32g, folium sennae 30g, fructus cannabis 25g, flax benevolence 25g, wind-weed 30g, reed rhizome 20g, dried immature fruit of citron orange 30g, banksia rose 32g, Radix Glycyrrhizae 30g, Radix Codonopsis 20g, Radix Astragali 30g and date 25g, drop into mixer and stir 40 minutes, fully mix; The mixture of acquisition is poured into and in pulverizer, pulverized and sieve, through 100 objects screenings, obtain Chinese medicine additive powder;
Second step, get each component in feed adhesive: Strong flour 80g and starch 30g, add 35g water to start modified, refining temperature is 60 ℃, the dry feed adhesive that obtains after stirring;
The 3rd step, pulverizes after corn 5kg, wheat 2kg, wheat bran 4kg are mixed, and grinding particle size is 400mm, obtains feed vector;
The 4th step; by the Chinese medicine additive powder 200g, the feed adhesive 500g of acquisition that obtain; the feed vector 5000g obtaining and nutritious supplementary pharmaceutical 200g mix; putting into multiplex mixer stirs 120 minutes; after taking-up, put into ring mode bulking machine expanded; control the temperature of bulking machine between 85 ℃; the expanded time is 1 hour; the aridity of controlling material to be extruded is 95%; after taking-up, proceed in ring mode grit machine and be produced into and precipitate hard particles feed; then by 60 meshes, sieve, obtain feed 1.
Wherein, nutritious supplementary pharmaceutical is branched-chain amino acid, vitamin C, vitamin E, mineral trace element and amylase.
Embodiment 3 feeds 2
The first step, by each component of described Chinese medicine additive: aloe 35g, dried rhizome of rehmannia 15g, fringed iris herb 25g, folium sennae 30g, fructus cannabis 25g, flax benevolence 25g, wind-weed 24g, reed rhizome 20g, dried immature fruit of citron orange 30g, banksia rose 22g, Radix Glycyrrhizae 30g, Radix Codonopsis 20g, Radix Astragali 30g and date 20g drop into mixer and stir 50 minutes, fully mix; The mixture of acquisition is poured into and in pulverizer, pulverized and sieve, through 200 objects screenings, obtain Chinese medicine additive powder fine powder;
Second step, get each component in feed adhesive: Strong flour 70g and starch 20g, add 30g water to start modified, refining temperature is 70 ℃, the dry feed adhesive that obtains after stirring;
The 3rd step, pulverizes after corn 4kg, soybean 1kg, wheat bran 5kg are mixed, and grinding particle size is 500mm, obtains feed vector;
The 4th step; by the Chinese medicine additive powder 400g, the feed adhesive 800g of acquisition that obtain; the feed vector 6000g obtaining and nutritious supplementary pharmaceutical 300g mix; putting into multiplex mixer stirs 150 minutes; after taking-up, put into ring mode bulking machine expanded; control the temperature of bulking machine between 90 ℃; the expanded time is 2 hours; the aridity of controlling material to be extruded is 90%; after taking-up, proceed in ring mode grit machine and be produced into and precipitate hard particles feed; then by 80 meshes, sieve, obtain feed 2.
Wherein, nutritious supplementary pharmaceutical is branched-chain amino acid.
Clinical trial
(1) animal used as test
Select 120 4 monthly ages to suffer from the pig of constipation, male and female are random, all suffer from constipation, and defecation is discharged feces less or not, and anorexia is reluctant activity.
(2) control of feeding environment
Duration of test, all tests complete between isolation, and keep that colony house is dried, cleans, feeds, drinking-water and feeding and management carry out according to a conventional method, be consistent as far as possible.
(3) experimental technique
Random packet, is divided into three groups, uses respectively the feed 1(embodiment group 1 of the embodiment of the present invention 2) and the feed 2(embodiment group 2 of embodiment 3), according to the normal mode of feeding, feed; Control group adopts every sodium hydrosulfide 6g+ artificial salt 6g, and spice is for oral administration, and every day three times, according to the normal mode of the feeding conventional feed of feeding.After one week for the treatment of, observe and make a record.
(4) effect criterion and observational technique
Cure: pig constipation recovery from illness, and some illnesss, as poor appetite, the not recovery from illness such as defecation.
Effective: pig constipation is effectively alleviated, there is very large alleviation.
Invalid: pig constipation is not effectively alleviated.
Wherein, efficient is that healing number and significant figure account for total percentage.
(5) result
The table 1 treatment results table of comparisons
Figure 770275DEST_PATH_IMAGE001
From the data of table 1, use the result for the treatment of of the forage feed pig treatment constipation of the embodiment of the present invention 2 and embodiment 3 to be obviously better than control group.
Model case 1
In January, 2012,2 pigs of Wang suffer from constipation, suffer from constipation and have two months, and sick just anorexia, belly expand, discharge feces stagnant slow, thirsty and often drinking-water, it is uneasy that performance is slight, sends rumble cry, and with hand, pressing belly has pain reaction, gradually becoming afterwards appetite disappears, lassitude, conjunctival congestion, enriches.Through taking the feed 1 of the embodiment of the present invention 2 preparations, to feed continuously 7,2 ill pigs are all fully recovered.
Model case 2
In May, 2013,1 pig of Lee suffers from constipation first quarter moon, and anorexia, belly expand, stagnant slow, the thirsty and normal drinking-water of discharging feces, and lassitude, conjunctival congestion, enriches.Through taking the feed 2 of the embodiment of the present invention 3 preparations, normally take every day, feeds continuously recovery from illness 5.
All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only preferred embodiment of the present invention, is not the present invention to be done to the restriction of other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (8)

1. the feed that is used for the treatment of pig constipation, it is characterized in that, comprise: feed vector, feed adhesive, nutritious supplementary pharmaceutical and Chinese medicine additive, described Chinese medicine additive comprises: aloe, the dried rhizome of rehmannia, fringed iris herb, folium sennae, fructus cannabis, flax benevolence, the wind-weed, reed rhizome, the dried immature fruit of citron orange, the banksia rose, Radix Glycyrrhizae, Radix Codonopsis, the Radix Astragali and date.
2. feed according to claim 1, it is characterized in that, in described Chinese medicine additive, the ratio of weight and number of various components is: aloe 14-35 weight portion, dried rhizome of rehmannia 10-35 weight portion, fringed iris herb 10-35 weight portion, folium sennae 15-30 weight portion, fructus cannabis 20-35 weight portion, flax benevolence 10-25 weight portion, wind-weed 15-34 weight portion, reed rhizome 10-20 weight portion, dried immature fruit of citron orange 15-30 weight portion, banksia rose 14-32 weight portion, Radix Glycyrrhizae 15-30 weight portion, Radix Codonopsis 10-20 weight portion, Radix Astragali 10-30 weight portion and date 15-25 weight portion.
3. feed according to claim 1 and 2, it is characterized in that, in described Chinese medicine additive, the ratio of weight and number of various components is: aloe 20-35 weight portion, dried rhizome of rehmannia 15-35 weight portion, fringed iris herb 20-35 weight portion, folium sennae 15-20 weight portion, fructus cannabis 15-35 weight portion, flax benevolence 15-25 weight portion, wind-weed 15-30 weight portion, reed rhizome 10-15 weight portion, dried immature fruit of citron orange 20-30 weight portion, banksia rose 20-32 weight portion, Radix Glycyrrhizae 20-30 weight portion, Radix Codonopsis 15-20 weight portion, Radix Astragali 10-20 weight portion and date 15-20 weight portion.
4. according to the feed described in claim 1-3 any one, it is characterized in that, with respect to 100 weight portion feed vectors, the addition of described feed adhesive is 10~20 weight portions, the addition of described nutritious supplementary pharmaceutical is 2~6 weight portions, and the addition of described Chinese medicine additive is 4~8 weight portions.
5. according to the feed described in claim 1-4 any one, it is characterized in that, described nutritious supplementary pharmaceutical is one or more in amino acid, vitamin, mineral trace element and enzyme preparation; Described feed adhesive is Strong flour and starch, and the weight fraction ratio of described Strong flour and described starch is: 2-3:1-2.
6. a preparation method for the feed as described in claim 1-5 any one, is characterized in that, described preparation method comprises:
The first step, drops in proportion mixer by each component of described Chinese medicine additive and stirs 20-50 minute, fully mixes; The mixture of acquisition is poured into and in pulverizer, pulverized and sieve, through the screening of 100-300 object, obtain Chinese medicine additive powder fine powder;
Second step, each component of getting in feed adhesive is mixed, and adds water to start modified, and refining temperature is 60-70 ℃, the dry feed adhesive that obtains after stirring, with respect to the feed adhesive of 100 weight portions, the addition of described water is 20-30 weight portion;
The 3rd step, by described corn, wheat, soybean, wheat bran and Chinese sorghum, one or more are pulverized after mixing, and grinding particle size is 400~600mm, obtains feed vector;
The 4th step; the feed adhesive that the Chinese medicine additive powder that the first step is obtained, second step obtain; the feed vector that the 3rd step obtains and nourishing additive agent mix; putting into multiplex mixer stirs 120 minutes~150 minutes; after taking-up, put into ring mode bulking machine expanded; control the temperature of bulking machine between 80 ℃~90 ℃; the expanded time is 1~2 hour; the aridity of controlling material to be extruded is 90%~95%; after taking-up, proceed in ring mode grit machine and be produced into and precipitate hard particles feed; then use 50 order ~ 100 meshes to sieve, obtain described feed.
7. a Chinese medicine additive that is used for the treatment of pig constipation, it is characterized in that, in described Chinese medicine additive, the ratio of weight and number of various components is: aloe 14-35 weight portion, dried rhizome of rehmannia 10-35 weight portion, fringed iris herb 10-35 weight portion, folium sennae 15-30 weight portion, fructus cannabis 20-35 weight portion, flax benevolence 10-25 weight portion, wind-weed 15-34 weight portion, reed rhizome 10-20 weight portion, dried immature fruit of citron orange 15-30 weight portion, banksia rose 14-32 weight portion, Radix Glycyrrhizae 15-30 weight portion, Radix Codonopsis 10-20 weight portion, Radix Astragali 10-30 weight portion and date 15-25 weight portion.
8. the preparation method who is used for the treatment of the Chinese medicine additive of pig constipation claimed in claim 7, is characterized in that, described preparation method comprises:
The first step, drops in proportion mixer by each component of described Chinese medicine additive and stirs 20-50 minute, fully mixes;
Second step, the mixture that the first step is obtained is poured into and in pulverizer, is pulverized and sieve, through the screening of 100-300 object, acquisition Chinese medicine additive powder.
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CN104824463A (en) * 2015-05-25 2015-08-12 袁春梅 Formula feed for cattle and preparation method thereof
CN105362733A (en) * 2015-10-29 2016-03-02 陈光辉 Drug for treating constipation
CN105595028A (en) * 2016-02-01 2016-05-25 安徽申亚农牧科技有限公司 Pure plant fermented feed capable of preventing and treating constipation of sows at gestation period
CN106234791A (en) * 2016-08-02 2016-12-21 山东新希望六和集团有限公司 With feed additive and preparation method thereof before and after a kind of Farrowing
CN106309967A (en) * 2016-08-20 2017-01-11 枞阳县金源畜牧养殖有限责任公司 Medicament for treating constipation of pregnant sows
CN106472828A (en) * 2016-07-13 2017-03-08 师红伟 A kind of mixed feed additive of prevention iron deficiency anemia and preparation method thereof

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CN101904449A (en) * 2010-08-13 2010-12-08 广西商大科技有限公司 Functional premixing agent for improving sow constipation
CN103566174A (en) * 2013-11-27 2014-02-12 镇江天和生物技术有限公司 Compound Chinese herbal medicine extracting solution for preventing and treating sow constipation and preparation method thereof

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CN104824463A (en) * 2015-05-25 2015-08-12 袁春梅 Formula feed for cattle and preparation method thereof
CN105362733A (en) * 2015-10-29 2016-03-02 陈光辉 Drug for treating constipation
CN105595028A (en) * 2016-02-01 2016-05-25 安徽申亚农牧科技有限公司 Pure plant fermented feed capable of preventing and treating constipation of sows at gestation period
CN106472828A (en) * 2016-07-13 2017-03-08 师红伟 A kind of mixed feed additive of prevention iron deficiency anemia and preparation method thereof
CN106234791A (en) * 2016-08-02 2016-12-21 山东新希望六和集团有限公司 With feed additive and preparation method thereof before and after a kind of Farrowing
CN106309967A (en) * 2016-08-20 2017-01-11 枞阳县金源畜牧养殖有限责任公司 Medicament for treating constipation of pregnant sows

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