CN106472828A - A kind of mixed feed additive of prevention iron deficiency anemia and preparation method thereof - Google Patents
A kind of mixed feed additive of prevention iron deficiency anemia and preparation method thereof Download PDFInfo
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- CN106472828A CN106472828A CN201610548434.4A CN201610548434A CN106472828A CN 106472828 A CN106472828 A CN 106472828A CN 201610548434 A CN201610548434 A CN 201610548434A CN 106472828 A CN106472828 A CN 106472828A
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- feed additive
- mixed feed
- iron deficiency
- deficiency anemia
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Abstract
The invention discloses a kind of mixed feed additive of prevention iron deficiency anemia and preparation method thereof, belong to animal feed additive field, it includes ferrous fumarate 46%～70%, ferrous lactate 6%～10%, glycine ferrouss 15%～25%, L ascorbic acid 5%～7%, thiamine hydrochloride 0.2%～0.6%, cobalamin 0.02%～0.06%, acidity regulator 2%～6%, flavoring agent 1%～6%.Its preparation method is the fine powder that described crushing material becomes more than 100 mesh, after weighing in proportion, mix homogeneously, adds binding agent, makes soft material, 60～80 mesh sieves are pelletized, 45 DEG C～55 DEG C dryings, 1.5～3.5 hours drying times, after drying to pellet moisture is below 10%, dry particl crosses 60～80 mesh sieve granulate, as finished product.The invention has the beneficial effects as follows：Various component proportions are appropriate, and after granulating process, effective protection ferrous irons are not oxidized, add 0.04%～0.05% can effectively prevent animal iron deficiency anemia to occur in mixed feed.
Description
Technical field
The present invention relates to animal feed additive field is and in particular to a kind of mixed feed of prevention iron deficiency anemia adds
Plus agent.
Background technology
Blood is made up of blood plasma and hemocyte, and hemocyte includes erythrocyte, leukocyte and platelet, main in erythrocyte
Composition is hemoglobin, accounts for the 32% of its weight in wet base, the 97% of dry weight；Hemoglobin is made up of globin and haemachrome, each
Haemachrome forms a ring by four pyroles subunits again, and ring center is a ferrous ion, and ferrum is the important former of participation hemopoietic
Material.
The average life of erythrocyte is 120 days, has a number of erythrocyte to be updated daily, in normal physiological feelings
Under condition, erythrocyte has certain morphosiss, and has metastable quantity, and anemia refers to that the erythrocyte in blood is fewer than normally
State；The reason anemia, is very many, and it is common cause that the erythropoiesis that shortage hemopoietic raw material ferrum element causes reduce, generally
Referred to as iron deficiency anemia.
The animal appetite that anemia occurs reduces, malnutrition, and the speed of growth is slack-off, and skin or cockscomb are substantially pale, by hair
Inverse vertical, spirit is depressed, and resistance is poor, liable to illness；Observe by the naked eye and get final product tentative diagnosis, surveyed using hemoglobin determinator
Determine animal blood content of hemoglobin can make a definite diagnosis further.
At present, the method to animal iron supplement is to add single ferrous sulfate or ferrous fumarate or sweet in animal feed
Propylhomoserin is ferrous, because ferrous sulfate is cheap, more from ferrous sulfate.
The drawbacks of current ferrous supplement method has very many, iron containing compoundses have different chemical characteristics first, in animal body
Inside there are different absorptions, transporting mode passage, be used alone a certain iron preparation, exist that absorption pattern is single, absorbance is low
Defect；Secondly ferrous sulfate, ferrous fumarate and glycine ferrouss are all ferrous irons, and ferrous irons are unstable to be easily oxidized to three
Valency ferrum, greatly reduces absorbance；Last iron supplement product is unprocessed, and iron taste is big, affects animal palatability, reduces animal
Feed intake.
Will be to put prevention first for animal iron deficiency anemia, anti-overweighting is controlled, in Animal husbandry production, in the urgent need to exploitation one
Plant easy to use, the mixed feed additive of the prevention iron deficiency anemia of definite effect.
Content of the invention
It is an object of the invention to provide the mixed feed additive formulations being made up of variety classes iron containing compoundses and
Its preparation method, and add protective agent and flavoring agent, improve ferrous stability, improve palatability.
The present invention is achieved by the following technical solutions.
A kind of prevention iron deficiency anemia mixed feed additive it is characterised in that：Former by following percentage by weight
Material composition.
Ferrous fumarate 46%～70%
Ferrous lactate 6%～10%
Glycine ferrouss 15%～25%
L-AA 5%～7%
Thiamine hydrochloride 0.2%～0.6%
Cobalamin 0.02%～0.06%
Acidity regulator 2%～6%
Flavoring agent 1%～6%
Preferably, a kind of prevention iron deficiency anemia mixed feed additive it is characterised in that：By following weight hundred
Divide the raw material composition of ratio.
Ferrous fumarate 46%
Ferrous lactate 10%
Glycine ferrouss 25%
L-AA 7%
Thiamine hydrochloride 0.6%
Cobalamin 0.06%
Acidity regulator 6%
Flavoring agent 5.34%
Described, acidity regulator is one of citric acid, malic acid, sorbic acid, fumaric acid or two or more combinations,
Flavoring agent is the combination of one of sucrose and/or glucose or two kinds.
Described, a kind of mixed feed addictive preparation method of prevention iron deficiency anemia, comprise the steps：More than inciting somebody to action
Material is respectively crushed into fine powder more than 100 mesh for the fineness, after weighing in proportion, mix homogeneously, and add binding agent, make soft
Material, 60～80 mesh sieves pelletize, 45 DEG C～55 DEG C dryings, 1.5～3.5 hours drying times, be dried to pellet moisture 10% with
After lower, dry particl crosses 60～80 mesh sieve granulate, as finished product.
The addition of described mixed feed additive is account for basal diet quality 0.04%～0.05%.
In the mixed feed additive of the present invention, ferrous fumarate is a kind of organic acid ferrum, iron-holder 30.6%, slightly soluble
Yu Shui, moisture is low, stable in properties.
Ferrous lactate is a kind of organic acid ferrum, iron-holder 19.4%, and water soluble does not have zest, Bu Huiyin to gastrointestinal
Play the untoward reaction such as constipation, Nausea and vomiting.
Glycine ferrouss are iron-amino acid chelates, iron-holder 17%, no iron taste, soluble in water.
L-AA is a kind of water soluble vitamins, has stronger reproducibility, ferric iron back can be become ferrous irons,
Promote the absorption of ferrum.
Thiamine hydrochloride is one of important component of coenzyme, plays synergistic function.
Cobalamin is a kind of vitamin B group being made up of the porphyrinses containing cobalt, is also that erythropoiesis are indispensable
Few important element.
Acidity regulator is the material adjusting pH, and ferrous ion is stable in sour environment, is difficult to be oxidized to three
Valency ferrum.
Flavoring agent can improve the palatability of additive, makes feedstuff tastier, promotes animal appetite, also has certain
Nutritive value.
So the invention has the beneficial effects as follows：
1st, the mixed feed additive of the present invention, is made up of variety classes chemical constitution iron supplement raw material, compensate for single
The single deficiency of chemical constitution iron preparation absorption and transport channel, multiple sources of iron, simultaneously added with the effect having complementary advantages, can improve
The absorption rate to ferrum for the animal；
2nd, the mixed feed additive of the present invention, makes granular preparation, can be combined together various effective ingredient, more
Achieve well the protective effect to ferrous ion of acidity regulator and L-AA；
3rd, the mixed feed additive of the present invention, has flavoring agent, masks the poor taste of additive itself, can promote
Feed intake.
Specific embodiment
With reference to embodiment, the technology contents of the present invention are further explained.
Embodiment 1：
A kind of mixed feed additive of prevention iron deficiency anemia, is made up of the raw material of following percentage by weight：Rich horse
Acid ferrous 46%, ferrous lactate 10%, glycine ferrouss 25%, L-AA 7%, thiamine hydrochloride 0.6%, cobalamin
0.06%, acidity regulator 6%, flavoring agent 5.34%, its preparation method is that above material is respectively crushed into fineness in 100 mesh
Above fine powder, after weighing in proportion, mix homogeneously, add binding agent, make soft material, 60～80 mesh sieves are pelletized, 45 DEG C～
55 DEG C of dryings, 1.5～3.5 hours drying times, after drying to pellet moisture is below 10%, it is whole that dry particl crosses 60～80 mesh sieves
Grain, as finished product, this mixed feed additive, iron-holder 20.3%, 0.05% ratio in accounting for basal diet quality is added
To in basal diet, for animal edible.
Embodiment 2：
A kind of mixed feed additive of prevention iron deficiency anemia, is made up of the raw material of following percentage by weight：Rich horse
Acid ferrous 52%, ferrous lactate 9%, glycine ferrouss 22.5%, L-AA 6.5%, thiamine hydrochloride 0.5%, cobalamin
0.05%, acidity regulator 5%, flavoring agent 4.45%, its preparation method is that above material is respectively crushed into fineness in 100 mesh
Above fine powder, after weighing in proportion, mix homogeneously, add binding agent, make soft material, 60～80 mesh sieves are pelletized, 45 DEG C～
55 DEG C of dryings, 1.5～3.5 hours drying times, after drying to pellet moisture is below 10%, it is whole that dry particl crosses 60～80 mesh sieves
Grain, as finished product, this mixed feed additive, iron-holder 21.5%, 0.0475% ratio in accounting for basal diet quality adds
It is added in basal diet, for animal edible.
Embodiment 3：
A kind of mixed feed additive of prevention iron deficiency anemia, is made up of the raw material of following percentage by weight：Rich horse
Acid ferrous 58%, ferrous lactate 8%, glycine ferrouss 20%, L-AA 6%, thiamine hydrochloride 0.4%, cobalamin
0.04%, acidity regulator 4%, flavoring agent 3.56%, its preparation method is that above material is respectively crushed into fineness in 100 mesh
Above fine powder, after weighing in proportion, mix homogeneously, add binding agent, make soft material, 60～80 mesh sieves are pelletized, 45 DEG C～
55 DEG C of dryings, 1.5～3.5 hours drying times, after drying to pellet moisture is below 10%, it is whole that dry particl crosses 60～80 mesh sieves
Grain, as finished product, this mixed feed additive, iron-holder 22.7%, 0.045% ratio in accounting for basal diet quality is added
To in basal diet, for animal edible.
Embodiment 4：
A kind of mixed feed additive of prevention iron deficiency anemia, is made up of the raw material of following percentage by weight：Rich horse
Acid ferrous 64%, ferrous lactate 7%, glycine ferrouss 17.5%, L-AA 5.5%, thiamine hydrochloride 0.3%, cobalamin
0.03%, acidity regulator 3%, flavoring agent 2.67%, its preparation method is that above material is respectively crushed into fineness in 100 mesh
Above fine powder, after weighing in proportion, mix homogeneously, add binding agent, make soft material, 60～80 mesh sieves are pelletized, 45 DEG C～
55 DEG C of dryings, 1.5～3.5 hours drying times, after drying to pellet moisture is below 10%, it is whole that dry particl crosses 60～80 mesh sieves
Grain, as finished product, this mixed feed additive, iron-holder 23.9%, 0.0425% ratio in accounting for basal diet quality adds
It is added in basal diet, for animal edible.
Embodiment 5：
A kind of mixed feed additive of prevention iron deficiency anemia, is made up of the raw material of following percentage by weight：Rich horse
Acid ferrous 70%, ferrous lactate 6%, glycine ferrouss 15%, L-AA 5%, thiamine hydrochloride 0.2%, cobalamin
0.02%, acidity regulator 2%, flavoring agent 1.78%, its preparation method is that above material is respectively crushed into fineness in 100 mesh
Above fine powder, after weighing in proportion, mix homogeneously, add binding agent, make soft material, 60～80 mesh sieves are pelletized, 45 DEG C～
55 DEG C of dryings, 1.5～3.5 hours drying times, after drying to pellet moisture is below 10%, it is whole that dry particl crosses 60～80 mesh sieves
Grain, as finished product, this mixed feed additive, iron-holder 25.1%, 0.04% ratio in accounting for basal diet quality is added
To in basal diet, for animal edible.
Contrast test：
1. test material and method：
The preparation of 1.1 test feeds：With reference to NY/T 65-2004 swine rearing standard, design microelement pre-mix material formula,
It is shown in Table 1, copper sulphate pentahydrate, zinc sulfate monohydrate, manganese sulfate monohydrate, potassium iodate, Monohydrated selenium dioxide in microelement pre-mix material raw material composition
The ratio of sodium is the same, according to ferrous sulfate, ferrous fumarate, ferrous lactate, glycine ferrouss, embodiment 1, embodiment 2, implements
Example 3, embodiment 4, the iron-holder of embodiment 5 are converted to same iron content standard, make 9 kinds of testing materials；This trace element premix
Copper content 6000mg/kg in material, iron content 102000mg/kg, Zn content 105000mg/kg, manganese content 4000mg/kg, iodine contains
Amount 120mg/kg, Se content 270mg/kg；Addition in mixed feed for this microelement pre-mix material is 0.1%, and cooperation is raised
Copper content 6mg/kg in material, iron content 102mg/kg, Zn content 105mg/kg, manganese content 4mg/kg, content of iodine 0.12mg/kg,
Se content 0.27mg/kg；During test, the compound feed prescription of feeding is：Semen Maydiss 30%, popcorn 24.5%, wheat-middlings 5%,
Swelling soya dreg 18%, fermented bean cake 7%, whey powder 5%, fish flour 5%, Lactose 2%, Oleum Glycines 0.75%, calcium citrate 0.75%,
Calcium hydrogen phosphate 1.2%, lysine 0.31%, Methionine 0.1%, threonine 0.04%, probiotics 0.1%, piglet specific complex
Enzyme 0.1%, piglet special vitamin premix 0.05%, microelement pre-mix material 0.1%, add up to absolutely.
Table 1 microelement pre-mix material formula %
The selection of 1.2 test pig：Select the close two-way cross sow 90 that grows up of kind, parity, body weight, be divided into 9
Group, every group 10.
1.3 test method：Give birth to piglet in sow and start within the 7th day to piglet feeding as above testing material, piglet is weaned for 21 days,
Proceed to conservation pigsty further according to test group after wean, continue feeding experiment material, be tested to wean and terminate for latter 10 days；Whole examination
Phase of testing carries out feeding and management by same feeding manner, immune programme for children, and records each group feed intake；During off-test, to piglet
Weigh, calculate the feed intake of experimental period, randomly draw 25 piglets in each experimental group, use in the same time same blood red
Protein assay measures the content of hemoglobin of piglet；According to《Today pig industry》06 phase in 2015, piglet hemoglobin detects
Technology and evaluation methodology, Hb H b≤9.0 gram/100 milliliter are anemia, calculate the shared test of anemia piglet of each test group
The ratio of pig.
2. result and analysis
Each group feed intake, content of hemoglobin is shown in Table 2.
Table 2 tests each group feed intake, content of hemoglobin feed intake kg
Ferrous sulfate group anemia incidence highest, ferrous fumarate group, ferrous lactate group, the morbidity of glycine ferrouss group anemia
Rate averagely 24%, embodiment 1, embodiment 2, embodiment 3, embodiment 4, embodiment 5 anemia incidence average out to 4.8%, lean
Blood sickness rate substantially reduces, and embodiment 1, embodiment 2, embodiment 3, embodiment 4, the feed intake of 5 groups of piglets of embodiment
Higher than other test group, especially test group 3 piglet feed intake highest, none anemia occurs, and the red hair of piglet skin is bright, and growth is strong
Health.
3. conclusion：Embodiment 1, embodiment 2, embodiment 3, embodiment 4, embodiment 5 are produced by the iron supplement of multiple chemical constitutions
Product form, and mutual supplement with each other's advantages effect substantially, adds protective agent and flavoring agent, improves ferrous stability, effectively prevents piglet
Iron deficiency anemia, and good palatability, piglet feed intake is high.
The above is only the preferred embodiment of the present invention it is noted that coming for those skilled in the art
Say, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should be regarded as
Protection scope of the present invention.
Claims (5)
1. a kind of mixed feed additive of prevention iron deficiency anemia is it is characterised in that raw material by following percentage by weight
Composition：Ferrous fumarate 46%～70%, ferrous lactate 6%～10%, glycine ferrouss 15%～25%, L-AA
5%～7%, thiamine hydrochloride 0.2%～0.6%, cobalamin 0.02%～0.06%, acidity regulator 2%～6%, flavoring agent
1%～6%.
2. a kind of mixed feed additive of prevention iron deficiency anemia according to claim 1 is it is characterised in that by such as
The raw material composition of lower percentage by weight：Ferrous fumarate 46%, ferrous lactate 10%, glycine ferrouss 25%, L-AA
7%, thiamine hydrochloride 0.6%, cobalamin 0.06%, acidity regulator 6%, flavoring agent 5.34%.
3. a kind of mixed feed additive of the prevention iron deficiency anemia described in claim 1 or 2 is it is characterised in that described
Acidity regulator be one of citric acid, malic acid, sorbic acid, fumaric acid or two or more combinations, flavoring agent be sugarcane
The combination of sugar and/or one of glucose or two kinds.
4. mixed feed additive of a kind of prevention iron deficiency anemia described in claim 1 or 2 and preparation method thereof, it is special
Levy and be, including following preparation process：Above material is respectively crushed into fine powder more than 100 mesh for the fineness, weighs in proportion
Afterwards, mix homogeneously, adds binding agent, makes soft material, and 60～80 mesh sieves are pelletized, 45 DEG C～55 DEG C dryings, and drying time 1.5～
3.5 hours, after drying to pellet moisture is below 10%, dry particl crossed 60～80 mesh sieve granulate, as finished product.
5. a kind of mixed feed additive of prevention iron deficiency anemia described in claim 1 or 2 is it is characterised in that described
The 0.04%～0.05% of daily ration quality based on the addition of mixed feed additive.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109010364A (en) * | 2018-09-12 | 2018-12-18 | 仲恺农业工程学院 | Ferrous glycinate enteric-coated sustained-release pellet with coating structure and preparation method thereof |
| CN113383858A (en) * | 2021-06-15 | 2021-09-14 | 湖南喜来高动物保健品有限公司 | Water-soluble glycine iron mixed additive and preparation method and equipment thereof |
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| CN101584417A (en) * | 2009-06-24 | 2009-11-25 | 河南雄峰科技有限公司 | A kind of sucking pig premix and the piglet preweaning feed that uses this premix to make |
| CN103750059A (en) * | 2014-01-27 | 2014-04-30 | 山东新希望六和集团有限公司 | Traditional Chinese medicine additive and feed for treating pig constipation and preparation method of traditional Chinese medicine additive and feed |
| CN105192318A (en) * | 2015-10-27 | 2015-12-30 | 南宁市泽威尔饲料有限责任公司 | Composite organic iron supplementing agent |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101584417A (en) * | 2009-06-24 | 2009-11-25 | 河南雄峰科技有限公司 | A kind of sucking pig premix and the piglet preweaning feed that uses this premix to make |
| CN103750059A (en) * | 2014-01-27 | 2014-04-30 | 山东新希望六和集团有限公司 | Traditional Chinese medicine additive and feed for treating pig constipation and preparation method of traditional Chinese medicine additive and feed |
| CN105192318A (en) * | 2015-10-27 | 2015-12-30 | 南宁市泽威尔饲料有限责任公司 | Composite organic iron supplementing agent |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109010364A (en) * | 2018-09-12 | 2018-12-18 | 仲恺农业工程学院 | Ferrous glycinate enteric-coated sustained-release pellet with coating structure and preparation method thereof |
| CN113383858A (en) * | 2021-06-15 | 2021-09-14 | 湖南喜来高动物保健品有限公司 | Water-soluble glycine iron mixed additive and preparation method and equipment thereof |
| CN113383858B (en) * | 2021-06-15 | 2022-05-27 | 湖南喜来高动物保健品有限公司 | Water-soluble glycine iron mixed additive and preparation method and equipment thereof |
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