CN103719609A - Feed for lactating sows and preparation method thereof - Google Patents
Feed for lactating sows and preparation method thereof Download PDFInfo
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Abstract
The invention discloses feed for lactating sows and a preparation method thereof. The feed contains the following raw materials: millet, wheat, corn, glutinous rice, cottonseed meal, honey, brown sugar, spirulina, salt, bone meal and a drug which is used for treating the yellow scour of newborn piglets. The feed has the beneficial effects that the feed disclosed by the invention contains the drug which is used for treating the yellow scour of the newborn piglets, and the drug takes the treatment principle of fighting bacteria and diminishing inflammation, astringing to arrest dysentery and improving the immunity of the piglets and is used in a manner of being matched with other raw materials, so that not only is the immunity of the sows improved, but also the treatment of the yellow scour of the newborn piglets has the advantages of remarkable treatment effect, treatment in both symptoms and root causes, high curative ratio, no toxic or side effects and low cost.
Description
Technical field
The present invention relates to pig feed technical field, particularly a kind of sow in lactation and preparation method thereof.
Background technology
Chinese veterinarian's theory is thought: " the lower baby of breast has disease, must recuperate under medical treatment its mother, and female sick son is sick, female case peace ".Illustrate that cub morbidity has certain relation with its mother.Piglet yellow scour causes by enteropathogenic E．Coli, mostly the infection sources sow that normally carries disease germs.Piglet yellow scour is again early onset colibacillosis, is that the one of the newborn piglet that caused by the Escherichia coli of certain serotype is acute, lethal infectious disease.Cardinal symptom is to discharge yellow loose stool and acute death as feature.Cuing open inspection has enteritis and septicemia to change, have without obvious pathology.This disease has generation in the more area of China and pig farm, common are: O8:K88, K99, O60:K88, O138:K81, O139:K82, O141:K88, K85, O45, O115, O147, O101, the serotypes such as O149, these bacterial strains are most of can form enterotoxin, can cause piglet morbidity and dead.
Diagnostic point: 1, mainly piglet morbidity in life age in days of rear a few hours to 5 of epidemic characteristic, the most common with 1-3 age in days, above piglet seldom fell ill in one week.Growing and fattening pigs, big porker, the male and female pig that grows up lose morbidity; In farrowing, usually can make a lot of nest piglet morbidities season, every nest piglet invention reaches as high as 100%; The highest with the first tire sow litter incidence of disease, the death rate is also high.Also healthy when 2, clinical symptom piglet is born, sudden onset and death after fast person's a few hours.Sick pig cardinal symptom is to draw yellow dysentery, and excrement is yellow water sample mostly, includes curdled milk small pieces, along anus, flows down, and how it does not stay excrement mark around, easily out in the cold.When diarrhea is heavy, hind leg is stain by liquid manure; From the anus loose stool of emerging.Sick piglet is reluctant to suck the breast, become thin very soon, dewater, and finally because dying of exhaustion, dies.Can there is redness in gilt vaginal orifice tip, sick piglet essence.Urgency person loses diarrhea, health weakness, and the stupor that falls down to the ground is dead.3, cuing open inspection variation major lesions is gastroenteric catarch inflammation.Show as intestinal mucosa swelling, hyperemia or hemorrhage; Gastric mucosa redness; The congested enlargement of goldbeater's skin lymph node, tangent plane succulence; The heart, liver, kidney have sex change, and severe one has blutpunkte.4, bacterium separates with evaluation and gets fresh dead chitterlings leading portion content, is inoculated on wheat health culture medium, and the red bacterium colony of picking is made hemolytic test and biochemical test, or by Escherichia coli factor serum evaluation serotype.
At present, the control that is used for the treatment of piglet yellow scour disease is mainly: antibiotic or sulfonamide (as sulfamethyldiazine) therapy, and as injection liquid of gentamicin, intramuscular injection, once measures every 80,000 units, 1 day 2 times, is used in conjunction 3 days; Or kanamycin sulfate injection liquid, intramuscular injection, once measures 10-15 milligrams of every kg body weight, 1 day 2 times, is used in conjunction 3 days.But antibiotic easily makes germ develop immunity to drugs, and easily leaves in vivo.And Chinese medicine has no side effect, without the resistance to the action of a drug, there is metabolic function and the immunologic function of body of adjustment, there is again antivirus action, therefore body recovery is fast, do not recur after more, with herbal control be the concentrated problem of studying of many veterinary work persons in recent years.Because have drawn from nature, and, there is hypertoxic herbal medicine few, use clinically relatively standard, therefore Chinese herbal medicine can be more safer than Chinese patent drug and Western medicine; The side effect of Chinese herbal medicine is in this three minimum by comparison time, and the wide material sources of Chinese herbal medicine, and price can lower (except some fewer or national conditional medicines in source).The treatment curative effect of the treatment by Chinese herbs piglet yellow scour of developing is at present relatively good, there is relative low price, Chinese herbal medicine is from the Nature, resource is extensive and cheap, have nutrition and medicinal double action concurrently, for livestock and poultry diet or the medicinal effect that not only can reach disease preventing and treating, tachyauxesis separately, and have advantages of that long-term use noresidue, the low resistance to the action of a drug, low toxic and side effect and drug effect do not subtract, and therefore adopt Chinese herbal treatment piglet yellow scour to be more and more subject to people's attention.
Summary of the invention
Technical problem to be solved by this invention is the medicine that is to provide a kind of sow in lactation that is used for the treatment of piglet yellow scour, this medicine can anti-inflammation, dysentery and improve pigling immunity only, treatment piglet yellow scour has evident in efficacy, treat both principal and secondary aspect of disease, cure rate is high, have no side effect, the advantage that cost is low.
In order to realize foregoing invention object, the invention provides a kind of sow in lactation feed, described feed comprises following raw material: millet, wheat, corn, glutinous rice, cotton dregs, honey, brown sugar, spirulina, salt, bone meal and be used for the treatment of the medicine of piglet yellow scour.
Described feed is comprised of the raw material of following parts by weight: millet 50-70 weight portion, wheat 20-40 weight portion, corn 20-40 weight portion, glutinous rice 20-40 weight portion, cotton dregs 10-30 weight portion, honey 5-15 weight portion, brown sugar 5-10 weight portion, spirulina 10-20 weight portion, salt 3-8 weight portion, bone meal 10-15 weight portion and be used for the treatment of the medicine 5-15 weight portion of piglet yellow scour.
Described feed is preferably comprised of the raw material of following parts by weight: millet 54-65 weight portion, wheat 23-36 weight portion, corn 24-37 weight portion, glutinous rice 24-36 weight portion, cotton dregs 15-25 weight portion, honey 7-13 weight portion, brown sugar 6-8 weight portion, spirulina 12-16 weight portion, salt 5-7 weight portion, bone meal 12-14 weight portion and be used for the treatment of the medicine 6-12 weight portion of piglet yellow scour.
Described medicine comprise the Radix Astragali, the root of straight ladybell, glossy ganoderma, the bighead atractylodes rhizome, honeysuckle, fortune firethorn fruit, dark plum, the root of kudzu vine, matrimony vine, Chinese yam, in one's early teens, rhizoma alismatis, Poria cocos, Divine Comedy, sword brake herb, Plant Soot, marshmarigold-leaved beesia rhizome, the bark of ash, demutation grass, garden burnet, geranium wilfordii, polygonum flaccidum and digua fig stem and leaf.
Described medicine is preferably comprised of the raw medicinal material of following parts by weight: Radix Astragali 15-30 weight portion, the root of straight ladybell 10-20 weight portion, glossy ganoderma 15-30 weight portion, bighead atractylodes rhizome 10-30 weight portion, honeysuckle 20-30 weight portion, fortune firethorn fruit 10-20 weight portion, dark plum 10-19 weight portion, root of kudzu vine 10-15 weight portion, matrimony vine 10-20 weight portion, Chinese yam 20-30 weight portion, 10-15 weight portion in one's early teens, rhizoma alismatis 20-25 weight portion, Poria cocos 10-20 weight portion, Divine Comedy 10-20 weight portion, sword brake herb 10-20 weight portion, Plant Soot 10-20 weight portion, marshmarigold-leaved beesia rhizome 10-20 weight portion, bark of ash 10-20 weight portion, demutation grass 15-25 weight portion, garden burnet 10-20 weight portion, geranium wilfordii 20-30 weight portion, polygonum flaccidum 10-30 weight portion and digua fig stem and leaf 10-20 weight portion.
Described medicine is preferably comprised of the raw medicinal material of following parts by weight: Radix Astragali 18-25 weight portion, the root of straight ladybell 13-17 weight portion, glossy ganoderma 20-25 weight portion, bighead atractylodes rhizome 12-27 weight portion, honeysuckle 23-28 weight portion, fortune firethorn fruit 14-19 weight portion, dark plum 12-17 weight portion, root of kudzu vine 12-14 weight portion, matrimony vine 15-20 weight portion, Chinese yam 24-30 weight portion, 10-15 weight portion in one's early teens, rhizoma alismatis 20-25 weight portion, Poria cocos 13-17 weight portion, Divine Comedy 13-17 weight portion, sword brake herb 12-18 weight portion, Plant Soot 13-20 weight portion, marshmarigold-leaved beesia rhizome 12-18 weight portion, bark of ash 10-20 weight portion, demutation grass 20-25 weight portion, garden burnet 10-20 weight portion, geranium wilfordii 20-25 weight portion, polygonum flaccidum 20-25 weight portion and digua fig stem and leaf 10-20 weight portion.
Described medicine is preferably comprised of the raw medicinal material of following parts by weight: the Radix Astragali 23 weight portions, the root of straight ladybell 15 weight portions, glossy ganoderma 23 weight portions, the bighead atractylodes rhizome 23 weight portions, honeysuckle 25 weight portions, fortune firethorn fruit 16 weight portions, dark plum 14 weight portions, the root of kudzu vine 13 weight portions, matrimony vine 18 weight portions, Chinese yam 27 weight portions, 13 weight portions in one's early teens, rhizoma alismatis 23 weight portions, Poria cocos 15 weight portions, Divine Comedy 15 weight portions, sword brake herb 15 weight portions, Plant Soot 17 weight portions, marshmarigold-leaved beesia rhizome 15 weight portions, the bark of ash 15 weight portions, demutation grass 23 weight portions, garden burnet 15 weight portions, geranium wilfordii 23 weight portions, polygonum flaccidum 23 weight portions and digua fig stem and leaf 15 weight portions.
Wherein, the preparation method of described medicine comprises the following steps:
A, described raw medicinal material is put into after pulverizer is pulverized and crossed 120 order dusting covers, the fine powder amount that enable pass is crossed 120 mesh sieves is reaching 30%～40%, collects raw material fine powder by 120 mesh sieves standby, and particle remaining after sieving is standby;
B, particle remaining after sieving is put into the ethanol heating and refluxing extraction twice that the determining alcohol of 5～7 times of amounts is 85%, each 1～2 hour, extracted twice liquid is merged standing, obtain extract 1, the dregs of a decoction are standby;
C, the dregs of a decoction that in step b, alcohol extract is crossed are added to 5～7 times of water gaging heating and refluxing extraction 2 times, each 1～2 hour, No. 2 extracts are merged standing, obtain extract 2.
D, extract 1 and extract 2 are merged, filter 1.38 filtrate when reduced pressure concentration relative density is 50 ℃～60 ℃, reclaim ethanol, gained filtrate is adjusted to proportion to 1.06, pass into spray dryer and spray dryly, the compressed air pressure of mistake spray dryer shower nozzle is 4kg/m
2, hothouse hot stream temperature is 100 ℃, obtains raw material medicinal powder; The medicine that the raw material fine powder obtaining after step a is sieved mixes with raw material medicinal powder.
In order better to realize foregoing invention object, the invention provides a kind of preparation method of sow in lactation feed, described preparation method comprises the following steps:
(1) according to ratio of weight and number, take millet, wheat, corn, glutinous rice, cotton dregs, after mixing, be ground into 150-200 object powder, at the temperature bottom fermentation 4-7 days of 120-140 ℃, after fermentation, at 60-70 ℃ of temperature, dry and be ground into powder;
(2) according to ratio of weight and number, take honey, brown sugar, spirulina, salt, bone meal and medicine, and after fully mixing with the powder obtaining in described step (1), drop into granulator and granulate, pelleting temperature is 75-80 ℃, obtains pellet;
(3) pellet obtaining in described step (2) is spread on the ebullated bed of boiling drier, heat drying 10-15 minute, the import air temperature of heating is 120-130 ℃, obtains dry pellet.
The beneficial effect that the technical scheme that the embodiment of the present invention provides is brought is: feed of the present invention contains the medicine for the treatment of piglet yellow scour, medicine stops dysentery and improves pigling immunity as principle of reatment take anti-inflammation, convergence, medicine and other raw materials are used in conjunction with, not only improve the immunity of sow, and treatment piglet yellow scour has evident in efficacyly, to treat both principal and secondary aspect of disease, cure rate is high, have no side effect, the advantage that cost is low.
The specific embodiment
Chinese veterinarian's theory is thought: " the lower baby of breast has disease, must recuperate under medical treatment its mother, and female sick son is sick, female case peace ".Illustrate that cub morbidity has certain relation with its mother.Piglet yellow scour causes by enteropathogenic E．Coli, mostly the infection sources sow that normally carries disease germs.The cardinal symptom of piglet yellow scour is to discharge yellow loose stool and acute death as feature.Cuing open inspection has enteritis and septicemia to change, have without obvious pathology.Diagnostic point: 1, epidemic characteristic: mainly piglet morbidity in life age in days of rear a few hours to 5, the most common with 1-3 age in days, above piglet seldom fell ill in one week.Growing and fattening pigs, big porker, the male and female pig that grows up lose morbidity; In farrowing, usually can make a lot of nest piglet morbidities season, every nest piglet invention reaches as high as 100%; The highest with the first tire sow litter incidence of disease, the death rate is also high.2, clinical symptom: also healthy during piglet birth, sudden onset and death after fast person's a few hours.Sick pig cardinal symptom is to draw yellow dysentery, and excrement is yellow water sample mostly, includes curdled milk small pieces, along anus, flows down, and how it does not stay excrement mark around, easily out in the cold.When diarrhea is heavy, hind leg is stain by liquid manure; From the anus loose stool of emerging.Sick piglet is reluctant to suck the breast, become thin very soon, dewater, and finally because dying of exhaustion, dies.Can there is redness in gilt vaginal orifice tip, sick piglet essence.Urgency person loses diarrhea, health weakness, and the stupor that falls down to the ground is dead.3, cuing open inspection changes: major lesions is gastroenteric catarch inflammation.Show as intestinal mucosa swelling, hyperemia or hemorrhage; Gastric mucosa redness; The congested enlargement of goldbeater's skin lymph node, tangent plane succulence; The heart, liver, kidney have sex change, and severe one has blutpunkte.4, bacterium separates and identifies: get fresh dead chitterlings leading portion content, be inoculated on wheat health culture medium, the red bacterium colony of picking is made hemolytic test and biochemical test, or by Escherichia coli factor serum evaluation serotype.The present invention is take anti-inflammation, only dysentery and raising pigling immunity as principle of reatment, a kind of medicine for the treatment of piglet yellow scour is provided, has comprised: the Radix Astragali, the root of straight ladybell, glossy ganoderma, the bighead atractylodes rhizome, honeysuckle, fortune firethorn fruit, dark plum, the root of kudzu vine, matrimony vine, Chinese yam, in one's early teens, rhizoma alismatis, Poria cocos, Divine Comedy, sword brake herb, Plant Soot, marshmarigold-leaved beesia rhizome, the bark of ash, demutation grass, garden burnet, geranium wilfordii, polygonum flaccidum and digua fig stem and leaf.
Wherein, the pharmacological property of each raw medicinal material is:
The Radix Astragali: take qi-restoratives as main, energy invigorating qi for strengthening superficies, diuresis holder poison, apocenosis, expelling pus and promoting granulation.For insufficiency of vital energy and blood, sore cave in, purulence becomes not burst or burst and do not hold back person for a long time.The Radix Astragali has the function of good promoting pus discharge and tissue regeneration, i.e. the abscess suppuration myogenic of disunion for a long time.Modern medicine study shows, the Radix Astragali includes and multiple antibiotic effective ingredient, and can strengthen the immunologic function of body, therefore can also be used for preventing the generation of some infectious disease.< < book on Chinese herbal medicine meets former > > to carry: " all void of Radix Astragali energy tonifying five zang organs, controls arteries and veins string spontaneous perspiration, rushes down yin fire, removes lung heat, losslessly sends out, and has sweat to stop." be the good medicine of promoting resistance and defence disease.
The root of straight ladybell: sweet, cool.Function cures mainly: clearing heat and nourishing yin, moistens the lung and relieve the cough.Cure mainly tracheitis, pertussis, cough with lung heat, coughs up phlegm yellow thick.1. the impact on immunologic function: lumbar injection apricot leaf the root of straight ladybell decocting liquid (0.5g/ only) can obviously increase mouse peripheral blood medium size lymphocyte and T cell number; Thymus gland endolymph cell number and T cell number also have increase trend, can show raising Turnover of Mouse Peritoneal Macrophages phagocytic percentage; Mouse spleen weight be can obviously increase, but mouse spleen lymphocyte number and T cell number reduced.Show that the root of straight ladybell can improve Cellular Immunity and nospecific immunity, suppress humoral immunity.There is the function that regulates immunologic balance.The root of straight ladybell also can improve lymphocyte conversion ratio.2. phlegm-dispelling functions: gavage the root of straight ladybell decoction by 1g/kg dosage to rabbit and show to have certain phlegm-dispelling functions, it acts on sustainable more than 4 hours, but action intensity is not as good as pale reddish brown etc.3. antifungic action: the root of straight ladybell water logging agent (1:2) has inhibitory action in various degree to dermatophytes such as Austria Du big belly microspore tinea bacterium, wool sample microspore tinea bacterium in vitro.4. cardiotonic: 1% the root of straight ladybell preserved material has obvious cardiotonic to Isolated Toad Heart, isolated heart amplitude increases, and acts on sustainable 5 minutes.
Glossy ganoderma: property is sweet, flat; The thoughts of returning home, liver, spleen, lung, the kidney Five Classics.Cure mainly consumptive disease, cough, asthma, insomnia, indigestion, malignant tumour etc.Animal pharmacology shows experiment: glossy ganoderma has inhibitory action to nervous system, and the circulatory system has step-down and strengthens the effect of cardiac contractile force, and respiratory system is had to phlegm-dispelling functions, in addition, protects in addition liver, improves immunologic function, antibacterially waits effect.Have protecting liver and detoxication effect, the hepatic injury that glossy ganoderma causes multiple physics and chemistry and biological factor has protective effect.After no matter still occurring before liver damage occurs, take glossy ganoderma and all can protect liver, alleviate hepatic injury.Glossy ganoderma can promote the metabolism of liver to medicine, poisonous substance, for toxic hepatitis, has definite curative effect.Especially chronic hepatitis, glossy ganoderma can obviously be eliminated the symptoms such as dizziness, weak, nauseating, uncomfortable liver area, and can effectively improve liver function, makes indices be tending towards normal.So glossy ganoderma can be used for treating slow poisoning, all kinds of chronic hepatitis, cirrhosis, hepatosis.Also there is the effect to cardiovascular system; zoopery and clinical testing all show; glossy ganoderma is coronary artery dilator effectively; increase CF; improve Myocardial Microcirculation, strengthen the supply of myocardium oxygen and energy, therefore; myocardial ischemia is had to protective effect, can be widely used in treatment and the prevention of coronary heart diseases and angina pectoris etc.To high fat of blood patient, glossy ganoderma can obviously reduce cholesterolemia, lipoprotein and triglyceride, and the formation of energy prevention of arterial AP.For former of AP, there is the effect that reduces Arterial Cholesterol content, softening blood vessel, prevents further damage.And can improve local microcirculation, stop platelet aggregation.These effects have good preventive and therapeutic effect for polytype apoplexy.
The bighead atractylodes rhizome: bitter, sweet, temperature.Return spleen, stomach warp.Cure mainly strengthening the spleen and replenishing qi, eliminating dampness Li Shui, hidroschesis, antiabortive.Few for insufficiency of the spleen food, abdominal distension is had loose bowels, and phlegm and retained fluid is dizzy throbs with fear, oedema, spontaneous perspiration, fetal irritability.< < property of medicine opinion > > carries it: monarch, taste is sweet, pungent, nontoxic.The large wandering arthritis of energy master, diarrhea due to disorder of qi for many years, trusted subordinate's distending pain, the broken place food that disappears, appetizing, removes sputum, removes fever and chills, under stopping, lets out.Interarea light is happy, preserves youthful looks, and de-black.The swelling of harnessing the river is full, tells to vomit contraryly, and crymodynia in abdomen, vomits and diarrhoea incessantly, and the cold dysentery of stomach Qi deficiency.
Honeysuckle: taste is sweet, cold in nature, enters the heart, lung, stomach, large intestine channel, has clearing heat and detoxicating effect, and double can removing heat from the blood and relieve diarrhea is mainly used in affection of exogenous wind-heat, the hot poison of warm heat disease is contained, or warm disease is from the beginning of heat evil still at the part of the body cavity above the diaphragm housing the heart and lungs and when not descending; The malicious diarrhea of heat, the lower blood of stool; Heat temperature card; The sore carbuncle that hot poison gathers is from the beginning of the ， inflammation heat person of swelling and ache, and other skin infections, and this thing has good antipyretic effect, has antiinflammatory action, can promote leukocytic phagocytic function, and multiple pyococcus and pathogenic entero becteria are had to stronger bacteriostasis.
Fortune firethorn fruit: property is flat, sour-puckery flavor is nontoxic.Function cures mainly: invigorating the spleen disappears long-pending, promoting blood circulation and hemostasis.Control lump in the abdomen, dyspepsia, has loose bowels, dysentery, uterine bleeding, postpartum blood stasis.
Dark plum: sour and astringent and warm, seemingly have class in pawpaw, but this enters lung and receives, enter intestines puckery, enter muscle and bone soft, enter worm and lie prostrate, enter dead flesh, dislike meat, dislike mole and remove, worm obtains sour volt, and worm volt is only itched.The good medicine of killing parasites to relieve itshing.
The root of kudzu vine: induce sweat and bring down a fever, promote the production of body fluid, promoting eruption, rises positive antidiarrheal.For fever caused by exogenous pathogens headache, hypertension neck pain, thirsty, quench one's thirst, measles without adequate eruption, hot dysentery, have loose bowels.< < Compendium of Materia Medica > > carries: the root of kudzu vine, cool in nature, gas is flat, taste is sweet, tool heat-clearing, falls fire, all effects of toxin expelling.Modern medicine study shows: the isoflavonoid Puerarin in the root of kudzu vine has certain curative effect to hypertension, high fat of blood, hyperglycaemia and cardiovascular and cerebrovascular disease.Elevate a turnable ladder yang-energy, light clear liter of the antidiarrheal of the quenching the thirst root of kudzu vine fallen apart, and the property of medicine rises to be sent out, and willow is lifted yang-energy, and A healthy wind prevails to inspire body, and body fluid cloth is capable.Rise a clear positive air of taste and quench the thirst, antidiarrheal dysentery.Therefore be usually used in treating interior heat, quench one's thirst, measles is sent out not smooth thoroughly, the illnesss such as diarrhoea, dysentery.
Matrimony vine: modern study, the fruit of Chinese wolfberry has the blood sugar of reduction, lipotropy, and can antiatherosclerosis.The fruit of Chinese wolfberry is also for strengthening the body resistance to consolidate the constitution, and the good medicine that production of sperm is mended marrow, enriching yin and nourishing kidney, benefiting qi for tranquillization, improved the health, delays senility is evident in efficacy to chronic hepatitis, central retinitis, optic atrophy etc.; Diabetes, pulmonary tuberculosis etc. are also had to good therapeutic effect; To antitumor, protect the liver, step-down, ageing disorders hypoglycemic and the elderly's organ failure have very strong improvement effect.As tonic invigorator treatment suffer from a deficiency of the kidney each disease and liver and kidney disease curative effect excellent, can significantly improve plasma testosterone cellulose content in human body, reach the effect of keeping fit.Modern medicine study shows, matrimony vine has obvious inhibitory action to cancer cell in vitro, the immunologic function that can be used for preventing the diffusion of cancer cell and strengthen human body.
Chinese yam: taste is sweet, property is flat, enters lung, spleen, stomach warp, has tonifying spleen nourishing the stomach, and beneficial lung reinforces the kidney, the effect of nourishing Yin and promoting production of body fluid, be mainly used in weakness of the spleen and the stomach, the symptom such as it is poor that the food of the dysfunction of the spleen in transport is received less, the vexed diarrhoea of gastral cavity.
In one's early teens: pungent, temperature.Return spleen, stomach warp.Function cures mainly: drying damp and strengthening spleen, and warm stomach preventing or arresting vomiting.For internal retention of cold wetness, abdominal fullness and distention crymodynia, belch is vomitted contrary, do not feel like eating.Decoction, to the excitement of guinea pig in vitro intestinal tube low concentration, is all inhibitory action higher than 1% concentration and volatile oil saturated aqueous solution in one's early teens.With Pavlov's pouch test, 10% infusion 60-80ml pours into main stomach in one's early teens, surveys microgastria secretion situation, and result is showing on the total acid output of stomach the pepsic activity that raises without impact.1979, the reports such as ItokawaH, the alcohol extractive of seed is several without antagonism to mouse ascites sarcoma 180 in one's early teens.Lee in 1980, at reports such as coloured glazes, carries out chronic pharmacological evaluation by having threeway Pavlov's pouch dog, and leachate, on total acid output without obvious impact, but obviously raises peptic activity of stomach in one's early teens.
Rhizoma alismatis: taste is sweet; Light; Cold in nature.Return kidney; Urinary bladder channel.Function cures mainly: clearing damp and promoting diuresis; Expel the heat-evil treating stranguria.Main difficult urination; Heat is drenched puckery pain; Oedema turgor; Have loose bowels; Phlegmatic vertigo; Seminal emission.< < Amplification on Materia Medica > >: rhizoma alismatis, its merit is longer than row water especially.Zhang Zhongjing is said, and it is thirsty tired that water holds, difficult urination, or tell or rush down, wuling powder master it.Side is with rhizoma alismatis, old friend its with being longer than row water.< < herbal classic > > draws again Bian Que's cloud, takes patient's eyes puckery more, is really row discharging the water pathogen.The person that Zhang Zhongjing eight taste balls are used, also only draws and connects osmanthus, attached etc. returning with regard to kidney channel, not without his meaning.Allly take the loose people of rhizoma alismatis, do not have the not many persons of urine; Urine is both many, and here must kidney qi answer real? how moderns' stopping leak essence, dare not use.< < detailed outline > >: rhizoma alismatis, gas is flat, and taste is sweet and light, and light can oozing let out, and smell is all thin, and institute lets out down in order to water.Taste have damp and hot, nose heave and blurred vision tinnitus, rhizoma alismatis is oozed it and wets, heat is also with going, and rustic must order, clear gas is up, weather is bright refreshing, therefore rhizoma alismatis has foster the five internal organs, benefit strength, controlling head revolves, the merit of clever knowledge, if clothes fall order too for a long time, clear QI failing to ascend, Kidney-Yin latent consumption, pacify to obtain blurred vision not? Zhong Jing Dihuang Wan, with Poria cocos, rhizoma alismatis person, it is the perverse trend of getting it and rush down bladder, non-drawing connects also, ancients' tonic, must doublely rush down heresy, heresy goes that tonic is capable, one ward off one entire, this is mysterious, do not know this reason later age, single-minded in benefit, so for a long time clothes must to the evil of victory partially also.Legendary god of farming's book row rhizoma alismatis is in top grade, and duplicatus takes the light of making light of one's life by commiting suicide, look unfamiliar for a long time, and pottery, Soviet Union all think true, and stupid stealing doubted it.Rhizoma alismatis row watery diarrhea kidney, for a long time clothes and can not, be equipped with again this siddhi, it is wrong known.
Poria cocos: sweet, light, flat.The thoughts of returning home, lung, spleen, kidney channel.Function clearing damp and promoting diuresis, the peaceful heart of invigorating the spleen.For oedema oliguria, phlegm and retained fluid is dizzy throbs with fear, and insufficiency of the spleen food is few, and have loose bowels in loose stool, confused and worried, palpitation with fear insomnia.Eliminating dampness and diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative.Control difficult urination, oedema turgor, phlegm and retained fluid is coughed contrary, and the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.< < herbal classic > > carries it: " the contrary gas of the main chest side of body, sorrow is angerd frightened heresy and is probably throbbed with fear, knot pain under the heart, fever and chills dysphoria, coughs contraryly, and mouthful burnt tongue is dry, diuresis." < < does not record > >: " only quenches one's thirst, and likes to sleep, and large abdomen, drenches drop, phlegm water in diaphragm, and oedema is drenched knot.Open chest internal organs, adjust visceral-qi, cut down kidney heresy, long cloudy, beneficial strength, during guarantor god keeps." < < property of medicine opinion > >: " appetizing, preventing or arresting vomiting is contrary, kind tranquilizing mind.Main consumptive lung disease phlegm is stopped up.Control pediatric epilepsy scared, trusted subordinate's turgor, married woman's heat is drenched."
Divine Comedy: be the processed goods forming through fermentation after wholemeal and other drug (sweet wormwood, Siberian cocklebur, the buds such as polygonum flaccidum, almond, rde bean) mixing.Get Divine Comedy and put in pot, to fry to appearance and be coke black, inner coke yellow, take out, spray the water that disappears, cool, be stir-baked MASSA FERMENTATA MEDICI-NALIS.Divine Comedy forms through fermentation, and the product of all fermentations have the digestant effect of strengthening the spleen and stomach, therefore, for bad, the feeling of stuffiness in chest abdominal distension of the digestion due to diet internal injury, quite has effect.
Sword brake herb: lightly seasoned micro-hardship, cold in nature.Function cures mainly: heat-clearing, dampness removing, cool blood, removing toxic substances.Control dysentery, malaria, jaundice, gonorrhoea, lower blood, metrorrhagia, traumatic injury, tonsillitis, mumps, sore, eczema.
Plant Soot: pungent, temperature. enter liver, lung, stomach warp.Function cures mainly: hemostasis, disappears long-pending.Control haematemesis, bleeding from five sense organs or subcutaneous tissue, has blood in stool, and metrorrhagia, under band, is rushed down dysentery, dyspepsia, all sores of throat dispute.
Marshmarigold-leaved beesia rhizome: warm in nature, taste is pungent.Function cures mainly: drive wind, dissipating cold, damp dispelling and pain relieving.
The bark of ash: bitter, puckery, cold.Return liver, courage, large intestine channel.Function cures mainly: heat-clearing and damp-drying drug, inducing astrigency, improving eyesight.For hot dysentery, have loose bowels, leukorrhea with reddish discharge, red eye, swell pain, the raw screen film of order.
Demutation grass: light, flat.Function cures mainly: diuresis, menstruation regulating, enriching yin qi-restoratives.Cure mainly oedema, dizziness, tinnitus, infantile malnutrition, irregular menstruation, stomachache, baby diarrhea.
Garden burnet: property picric acid; Cold; Nontoxic, return liver; Lung; Kidney; Large intestine channel, effect cooling blood and hemostasis, clearing heat and detoxicating, detumescence sore.Effect classification hemostatic; Blood-cooling hemostatic.Cure mainly haematemesis, spitting of blood, bleeding from five sense organs or subcutaneous tissue, hematuria, has blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, leukorrhea with reddish discharge, sore, carbuncle and painful swelling, eczema, pruritus vulvae, scald, snake bite and insect sting.< < detailed outline > >: garden burnet, except part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels heat, control stool and urine blood trouble.Hemostasis, gets and cuts off sheet and fry use, and its tip can promoting circulation of blood, can not know.
Geranium wilfordii: pungent, bitter, flat.Return liver,kidney,spleen warp.Function cures mainly: wines used as antirheumatic, the network that stimulates the menstrual flow, antidiarrheal profit.For arthralgia due to wind-dampness, numbness contracture, muscles and bones is ached, dysentery.
Polygonum flaccidum: pungent, temperature.Function cures mainly: expelling wind and removing dampness, blood stasis removing analgesic, removing toxicity for detumescence, killing parasites to relieve itshing.For dysentery, gastroenteritis, diarrhoea, rheumatic arthritis, treating swelling and pain by traumatic injury, functional uterine bleeding; Venomous snake bite is controlled in external application, skin eczema.
Digua fig stem and leaf: hardship, cold.Heat-clearing, dampness removing, invigorates blood circulation, removing toxic substances.Control cough due to wind-heat evil, dysentery, oedema, jaundice, rheumatalgia pain, hemorrhoid hemorrhage, through closing, under band, children's indigestion, traumatic injury, nameless sores or boils.
Embodiment 1 medicine 1
The embodiment of the present invention provides a kind of medicine that is used for the treatment of piglet yellow scour, raw medicinal material by following parts by weight forms: the Radix Astragali 23 weight portions, the root of straight ladybell 15 weight portions, glossy ganoderma 23 weight portions, the bighead atractylodes rhizome 23 weight portions, honeysuckle 25 weight portions, fortune firethorn fruit 16 weight portions, dark plum 14 weight portions, the root of kudzu vine 13 weight portions, matrimony vine 18 weight portions, Chinese yam 27 weight portions, 13 weight portions in one's early teens, rhizoma alismatis 23 weight portions, Poria cocos 15 weight portions, Divine Comedy 15 weight portions, sword brake herb 15 weight portions, Plant Soot 17 weight portions, marshmarigold-leaved beesia rhizome 15 weight portions, the bark of ash 15 weight portions, demutation grass 23 weight portions, garden burnet 15 weight portions, geranium wilfordii 23 weight portions, polygonum flaccidum 23 weight portions and digua fig stem and leaf 15 weight portions.
The embodiment of the present invention also provides a kind of preparation method of the medicine that is used for the treatment of piglet yellow scour, comprises the following steps:
A, described raw medicinal material is put into after pulverizer is pulverized and crossed 120 order dusting covers, the fine powder amount that enable pass is crossed 120 mesh sieves is reaching 30%～40%, collects by the raw material fine powder of 120 mesh sieves, and particle remaining after sieving is standby;
B, particle remaining after sieving is put into the ethanol heating and refluxing extraction twice that the determining alcohol of 5～7 times of amounts is 85%, each 1～2 hour, extracted twice liquid is merged standing, obtain extract 1, the dregs of a decoction are standby;
C, the dregs of a decoction that in step b, alcohol extract is crossed are added to 5～7 times of water gaging heating and refluxing extraction 2 times, each 1～2 hour, No. 2 extracts are merged standing, obtain extract 2
D, extract 1 and extract 2 are merged, filter 1.38 filtrate when reduced pressure concentration relative density is 50 ℃～60 ℃, reclaim ethanol, gained filtrate is adjusted to proportion to 1.06, pass into spray dryer and spray dryly, the compressed air pressure of mistake spray dryer shower nozzle is 4kg/m
2, hothouse hot stream temperature is 100 ℃, obtains raw material medicinal powder; The medicine 1 that the raw material fine powder obtaining after step a is sieved mixes with raw material medicinal powder.
Using method: medicine 1 is dissolved in water and is gavaged according to the percentage by weight of 1:5; Every day three times gavages 5g medicine 1 at every turn, uses continuously 2-4 days.
Toxicity test
Select SD rat, give the Chinese medicine preparation oral liquid of the present invention of variable concentrations (18.0,6.0,2.0g crude drug/kg), every day gavage once, continuous 90 days, after last administration, 24 hours each groups are lived and are killed 1/2 animal (male and female half and half), and all the other 1/2 animals continue observation and live and kill after 2 weeks.Duration of test is observed outward appearance, general behavior, food ration, the changes of weight of animal, and after administration, the index checkings such as hematology (RBC, HB, granulophilocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, Histopathology are carried out in 90 days and drug withdrawal for 2 weeks.Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight gain are all without ANOMALOUS VARIATIONS; Three dosage groups and control group hematological examination, blood biochemical are learned, urine biochemical analysis is all in normal range (NR), between group without significant difference; Each group main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also has no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, according to result of the test medicine of the present invention, in the administration in continuous 90 days of high, medium and low three dosage, rat is had no significant effect, without clear and definite toxicity target organ and sensitive indicator, convalescence observation also has no retardance toxic reaction, points out the dosage safety of Chinese medicine preparation clinical practice of the present invention higher.
Embodiment 2 medicines 2
The embodiment of the present invention provides a kind of medicine that is used for the treatment of piglet yellow scour, medicine is comprised of the raw medicinal material of following parts by weight: the Radix Astragali 25 weight portions, the root of straight ladybell 17 weight portions, glossy ganoderma 25 weight portions, the bighead atractylodes rhizome 12 weight portions, honeysuckle 28 weight portions, fortune firethorn fruit 19 weight portions, dark plum 12 weight portions, the root of kudzu vine 14 weight portions, matrimony vine 20 weight portions, Chinese yam 30 weight portions, 10 weight portions in one's early teens, rhizoma alismatis 20 weight portions, Poria cocos 13 weight portions, Divine Comedy 17 weight portions, sword brake herb 18 weight portions, Plant Soot 13 weight portions, marshmarigold-leaved beesia rhizome 18 weight portions, the bark of ash 10 weight portions, demutation grass 25 weight portions, garden burnet 20 weight portions, geranium wilfordii 20 weight portions, polygonum flaccidum 25 weight portions and digua fig stem and leaf 20 weight portions.
The embodiment of the present invention also provides a kind of preparation method of the medicine that is used for the treatment of piglet yellow scour, and formulation is injection, and preparation method comprises the following steps:
The first step, by all raw medicinal materials co-grinding in proportion, boiling 2～4 times, each decocting time is 2 hours～3 hours, the water quality adding is 2～4 times of first step mixture quality, merges decoction liquor, filters, filtrate is concentrated into syrupy shape, adding determining alcohol is more than 95% ethanol, and the ethanol content adding is 1～2 times of mixture quality of the first step, after standing 12 hours～24 hours, centrifugal filtration, filtrate is adjusted to filtrate pH7～8 with 40%～50% NaOH;
Second step, the filtrate that the first step is obtained, adds 0.5%～1% active carbon and boils 18～22 minutes, filters, decarburization, injects water, and the crude drug concentration that makes parenteral solution is 2g/ml～4g/ml, filling sterilizing 1.5 hours～2 hours in 500ml saline bottle, after freezing a couple of days, filters.
Embodiment 3 feeds
The embodiment of the present invention provides a kind of sow in lactation feed, and described feed is comprised of the raw material of following parts by weight: millet 61 weight portions, wheat 29 weight portions, corn 29 weight portions, glutinous rice 30 weight portions, cotton dregs 19 weight portions, honey 10 weight portions, brown sugar 7 weight portions, spirulina 14 weight portions, salt 6 weight portions, bone meal 13 weight portions and be used for the treatment of medicine 9 weight portions of piglet yellow scour.
Wherein, the medicine that is used for the treatment of piglet yellow scour is the medicine 1. of the embodiment of the present invention 1
Feed producing method comprises the following steps:
(1) according to ratio of weight and number, take millet, wheat, corn, glutinous rice, cotton dregs, after mixing, be ground into 180 object powder, the temperature bottom fermentations of 130 ℃ 6 days, after fermentation, at 65 ℃ of temperature, dry and be ground into powder;
(2) according to ratio of weight and number, take honey, brown sugar, spirulina, salt, bone meal and medicine, and after fully mixing with the powder obtaining in described step (1), drop into granulator and granulate, pelleting temperature is 80 ℃, obtains pellet;
(3) pellet obtaining in described step (2) is spread on the ebullated bed of boiling drier, heat drying 13 minutes, the import air temperature of heating is 130 ℃, obtains dry pellet.
Clinical testing
1.1 for examination material
1.1.1 for examination animal
In Shandong Province in pig farm, Weifang City, choose at random all 60 of healthy sows after 3-5 day of the expected date of childbirth.
1.1.2 strains tested
The birth piglet phenomena of mortality are found in Jining City in Shandong Province, and severe diarrhea appears in other piglets, and ight soil pulping is aqueous, and yellow-white locates to stain liquid manure at afterbody, perineum and hind leg etc.Dead piglet is cutd open to inspection, find that intestinal mucosa is catarrhal inflammation, wherein duodenum hyperemia, hemorrhage, enteron aisle inflation, has volume yellow liquid, and mesenteric adenophyma is large, and liver kidney has coagulation necrosis kitchen range.ME is got duodenum, content streak inoculation, on Mai Kangkai plating medium, is done hemolytic test and biochemical test, by the cause of disease type challenge with E.coli two suckling pig separating, after 24 hours, there is yellow dysentery symptom, determine that dead piglet is that yellow dysentery is lethal.Using the cause of disease type Escherichia coli that separate as strains tested.
1.1.3 for reagent product
The medicine 1 of embodiment 1; The feed of embodiment 3; Conventional feed; Conventional medicament: large mycin parenteral solution, intramuscular injection, once measures every 80,000 units, 1 day 2 times, is used in conjunction 3 days.
1.2 test method
The mode of feeding 1.2.1 antenatal
Sow is divided into three groups at random, is experimental group 1, experimental group 2 and experimental group 3,20 every group, and the feed of feeding embodiment 3 in the antenatal 3-5 of sow of experimental group 1 days to seven days postpartum, the antenatal 3-5 of sow days of experimental group 2 and 3 fed conventional feed to seven days postpartum.
1.2.2 inoculation test and grouping
After the sow production of three experimental group, choose 60 sodium selenites as for examination piglet for every group, respectively as embodiment group 1, embodiment group 2 and control group, the cause of disease type Escherichia coli difference intravenous injection of cultivating is supplied to examination piglet.
1.2.3 test method
After infecting, piglet adopts respectively the treatment of different medicine, and wherein, embodiment group 1 is not used any medicine, and the sow of embodiment group 1 continue the to feed medicine of the embodiment of the present invention 3 is fed 3 days; The piglet of embodiment group 2 gavages the medicine 1 of the embodiment of the present invention 1, and medicine 1 is dissolved in water and gavages according to the percentage by weight of 1:5, every day three times, gavages 5g medicine 1 at every turn, uses continuously 3 days; Control group is used large mycin injection for treating, and every 80,000 units are once measured in intramuscular injection, 1 day 2 times, are used in conjunction 3 days.
1.2.4 observed and recorded
Infect rear clinical symptoms and the pathological change of observing each group of piglet, the result for the treatment of of record death toll after infecting, treating after finishing for three days.
2 results
2.1 criterion of therapeutical effect
Cure: ill grice diarrhoea stops, ight soil is shaped, and spirit, drinking-water, appetite are recovered normally substantially, in one week, without recidivist, is judged to healing;
Effective: ill piglet is basic shaping respectively, and spirit, drinking-water, appetite are recovered normally substantially, but have recidivist to be judged to effectively in one week.
Invalid: ill grice diarrhoea symptom does not disappear or sb.'s illness took a turn for the worse even death be judged to invalid.
Wherein, efficient for curing and effective percentage sum.
After 2.2 embodiment groups 1 infect, there are 27 piglets that have of yellow dysentery symptom, but through the feed of the embodiment of the present invention 3 that continues the to feed sow of feeding, piglet yellow scour transference cure.Observed result is as shown in table 1.
From the data of table 1: compared with control group, the forage feed sow of the application of the invention embodiment 3, can improve the resistance against diseases of piglet, and the medicine of embodiment 1 has evident in efficacy to the treatment of yellow dysentery of piglet, side effect is low, the advantage that treated effect is high; In long-term observation subsequently, find, the piglet that embodiment group 1 and embodiment group 2 are cured the again incidence of disease is starkly lower than the piglet of control group.
2.3 infect rear symptom and cut open inspection result
After infection, the symptom of ill piglet is: suffer from diarrhoea suddenly, ight soil is yellow starchiness or yellow water sample, and contain curdled milk small pieces.When sick piglet slack anus, seizure, can increase abdominal pressure because struggling or piping, often by anus, discharge loose stool, be water sample ejection.Dead piglet is cutd open to inspection, find that mucous membrane of small intestine is red and swollen congested or hemorrhage; Gassy, intestines wall attenuation, lax in small intestine.Gastric mucosa is rubescent, mesenteric adenophyma is large.Severe one, the internal organs such as the heart, liver, kidney have blutpunkte, and what have also has little necrosis region.
Concrete case
Case 1
Certain self-employed worker that raises pigs feeds sow and gives birth to 37 piglets, and be born and within latter about 12 hours, occur 3 dead piglets, other piglet burst diarrhoea, ight soil is yellow water sample, piglet slack anus, spirit is at a low tide, and dead piglet is cutd open after inspection, find that mucous membrane of small intestine redness is hemorrhage, the attenuation of intestines wall, gastric mucosa is rubescent.Be diagnosed as yellow dysentery of piglet.Use the medicine 1 of the embodiment of the present invention 1 to treat, medicine 1 is dissolved in water and is gavaged according to the percentage by weight of 1:5, every day three times, gavage 5g medicine 1 at every turn, use continuously after 3 days, 30 grice diarrhoeas disappear, recovery from illness; The symptoms such as 4 grice diarrhoeas of residue are obviously improved, and continue to use two days, and 4 piglets are all fully recovered.
Case 2
, there are 5 dead piglets in 54 of the 3 age in days suckling pigs that feed on certain pig farm, other piglet burst diarrhoea, and ight soil is yellow starchiness or yellow water sample, and contains curdled milk small pieces.When sick piglet slack anus, seizure, can increase abdominal pressure because struggling or piping, often by anus, discharge loose stool, be water sample ejection.Dead piglet is cutd open to inspection, find that mucous membrane of small intestine is red and swollen congested or hemorrhage; Gassy, intestines wall attenuation, lax in small intestine.Gastric mucosa is rubescent, mesenteric adenophyma is large.Severe one, the internal organs such as the heart, liver, kidney have blutpunkte, and what have also has little necrosis region.Be diagnosed as yellow dysentery of piglet.Use the medicine 2 of the embodiment of the present invention 2 to treat, intramuscular injection, each 2-5ml, every day 2 times, is used in conjunction 3 days; 40 piglet recoveries from illness; 7 piglets are effective, continual cure two days, also all recoveries from illness; Dead 2 piglets.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (8)
1. a sow in lactation feed, is characterized in that, described feed comprises following raw material: millet, wheat, corn, glutinous rice, cotton dregs, honey, brown sugar, spirulina, salt, bone meal and be used for the treatment of the medicine of piglet yellow scour.
2. sow in lactation feed according to claim 1, it is characterized in that, described feed is comprised of the raw material of following parts by weight: millet 50-70 weight portion, wheat 20-40 weight portion, corn 20-40 weight portion, glutinous rice 20-40 weight portion, cotton dregs 10-30 weight portion, honey 5-15 weight portion, brown sugar 5-10 weight portion, spirulina 10-20 weight portion, salt 3-8 weight portion, bone meal 10-15 weight portion and be used for the treatment of the medicine 5-15 weight portion of piglet yellow scour.
3. sow in lactation feed according to claim 1 and 2, it is characterized in that, described feed is comprised of the raw material of following parts by weight: millet 54-65 weight portion, wheat 23-36 weight portion, corn 24-37 weight portion, glutinous rice 24-36 weight portion, cotton dregs 15-25 weight portion, honey 7-13 weight portion, brown sugar 6-8 weight portion, spirulina 12-16 weight portion, salt 5-7 weight portion, bone meal 12-14 weight portion and be used for the treatment of the medicine 6-12 weight portion of piglet yellow scour.
4. according to the sow in lactation feed described in claim 1-3 any one, it is characterized in that, described medicine comprise the Radix Astragali, the root of straight ladybell, glossy ganoderma, the bighead atractylodes rhizome, honeysuckle, fortune firethorn fruit, dark plum, the root of kudzu vine, matrimony vine, Chinese yam, in one's early teens, rhizoma alismatis, Poria cocos, Divine Comedy, sword brake herb, Plant Soot, marshmarigold-leaved beesia rhizome, the bark of ash, demutation grass, garden burnet, geranium wilfordii, polygonum flaccidum and digua fig stem and leaf.
5. according to the sow in lactation feed described in claim 1-4 any one, it is characterized in that, described medicine is comprised of the raw medicinal material of following parts by weight: Radix Astragali 15-30 weight portion, the root of straight ladybell 10-20 weight portion, glossy ganoderma 15-30 weight portion, bighead atractylodes rhizome 10-30 weight portion, honeysuckle 20-30 weight portion, fortune firethorn fruit 10-20 weight portion, dark plum 10-19 weight portion, root of kudzu vine 10-15 weight portion, matrimony vine 10-20 weight portion, Chinese yam 20-30 weight portion, 10-15 weight portion in one's early teens, rhizoma alismatis 20-25 weight portion, Poria cocos 10-20 weight portion, Divine Comedy 10-20 weight portion, sword brake herb 10-20 weight portion, Plant Soot 10-20 weight portion, marshmarigold-leaved beesia rhizome 10-20 weight portion, bark of ash 10-20 weight portion, demutation grass 15-25 weight portion, garden burnet 10-20 weight portion, geranium wilfordii 20-30 weight portion, polygonum flaccidum 10-30 weight portion and digua fig stem and leaf 10-20 weight portion.
6. according to the sow in lactation feed described in claim 1-5 any one, it is characterized in that, described medicine is comprised of the raw medicinal material of following parts by weight: Radix Astragali 18-25 weight portion, the root of straight ladybell 13-17 weight portion, glossy ganoderma 20-25 weight portion, bighead atractylodes rhizome 12-27 weight portion, honeysuckle 23-28 weight portion, fortune firethorn fruit 14-19 weight portion, dark plum 12-17 weight portion, root of kudzu vine 12-14 weight portion, matrimony vine 15-20 weight portion, Chinese yam 24-30 weight portion, 10-15 weight portion in one's early teens, rhizoma alismatis 20-25 weight portion, Poria cocos 13-17 weight portion, Divine Comedy 13-17 weight portion, sword brake herb 12-18 weight portion, Plant Soot 13-20 weight portion, marshmarigold-leaved beesia rhizome 12-18 weight portion, bark of ash 10-20 weight portion, demutation grass 20-25 weight portion, garden burnet 10-20 weight portion, geranium wilfordii 20-25 weight portion, polygonum flaccidum 20-25 weight portion and digua fig stem and leaf 10-20 weight portion.
7. according to the sow in lactation feed described in claim 1-6 any one, it is characterized in that, the preparation method of described medicine comprises the following steps:
A, described raw medicinal material is put into after pulverizer is pulverized and crossed 120 order dusting covers, the fine powder amount that enable pass is crossed 120 mesh sieves is reaching 30%～40%, collects raw material fine powder by 120 mesh sieves standby, and particle remaining after sieving is standby;
B, particle remaining after sieving is put into the ethanol heating and refluxing extraction twice that the determining alcohol of 5～7 times of amounts is 85%, each 1～2 hour, extracted twice liquid is merged standing, obtain extract 1, the dregs of a decoction are standby;
C, the dregs of a decoction that in step b, alcohol extract is crossed are added to 5～7 times of water gaging heating and refluxing extraction 2 times, each 1～2 hour, No. 2 extracts are merged standing, obtain extract 2;
D, extract 1 and extract 2 are merged, filter 1.38 filtrate when reduced pressure concentration relative density is 50 ℃～60 ℃, reclaim ethanol, gained filtrate is adjusted to proportion to 1.06, pass into spray dryer and spray dryly, the compressed air pressure of mistake spray dryer shower nozzle is 4kg/m
2, hothouse hot stream temperature is 100 ℃, obtains raw material medicinal powder; The medicine that the raw material fine powder obtaining after step a is sieved mixes with raw material medicinal powder.
8. a preparation method for the sow in lactation feed as described in claim 1-7 any one, is characterized in that, described preparation method comprises the following steps:
(1) according to ratio of weight and number, take millet, wheat, corn, glutinous rice, cotton dregs, after mixing, be ground into 150-200 object powder, at the temperature bottom fermentation 4-7 days of 120-140 ℃, after fermentation, at 60-70 ℃ of temperature, dry and be ground into powder;
(2) according to ratio of weight and number, take honey, brown sugar, spirulina, salt, bone meal and medicine, and after fully mixing with the powder obtaining in described step (1), drop into granulator and granulate, pelleting temperature is 75-80 ℃, obtains pellet;
(3) pellet obtaining in described step (2) is spread on the ebullated bed of boiling drier, heat drying 10-15 minute, the import air temperature of heating is 120-130 ℃, obtains dry pellet.
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| CN103719609B (en) | 2015-01-07 |
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