CN104721672A - Traditional Chinese medicine preparation for treating adhesive intestinal obstruction and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating adhesive intestinal obstruction. The traditional Chinese medicine preparation comprises the following various raw material medicines: 10-20 parts of semen raphani, 10-20 parts of very light blue, 10-20 parts of fingered citron, 10-20 parts of acute turpinia leaf, 10-20 parts of delavay schefflera root, 10-20 parts of soya-bean oil, 10-20 parts of liriope spicata, 10-20 parts of Chinese hawthorn leaf, 1-10 parts of alangium platanifolium flower, 1-10 parts of kalimeris indica, 1-10 parts of clove bark, 1-10 parts of myristica fragrans, 1-10 parts of majoram, 1-10 parts of hericium erinaceus, 1-10 parts of honeysuckle, 1-10 parts of mint, 1-10 parts of quispualis indica, and 1-10 parts of rhizoma kaempferiae. The traditional Chinese medicine preparation disclosed by the invention has the effects of smoothing qi and lubricating intestines, dispelling wind and removing dampness, promoting qi circulation and dissipating blood stasis, smoothing circulation, and dredging food retention in intestines. The traditional Chinese medicine preparation disclosed by the invention is simple and convenient in production process, low in toxic and side effects, convenient to administrate, easy to manufacture, and low in cost.

Description

A kind of Chinese medicine preparation for the treatment of adhesive ileus and preparation method thereof

Technical field

The present invention relates to the medicinal preparation containing deriving from plant, animal or raw mineral materials, particularly a kind of Chinese medicine preparation for the treatment of adhesive ileus and preparation method thereof.

Background technology

Adhesive ileus refers to because a variety of causes causes intraperitoneal intestinal adhesion to cause intestinal contents can not pass through smoothly and run in intestinal.When intestinal contents is by being obstructed, then can produce the series of symptoms such as abdominal distention, stomachache, nausea and vomiting and dysporia.It belongs to mechanical intestinal obstruction category, can be divided into acute ileus and chronic intestinal obstruction by onset anxious delaying; Complete intestinal obstruction and incomplete intestinal obstruction can be divided into by blocking degree; High intestinal obstruction, low small intestine obstruction and obstruction of colon can be divided into by region of obstruction; Simple intestinal obstruction and strangulated intestinal obstruction is divided into for situation by intestinal tube blood.This disease part can obtain resolution of symptoms through non-operative treatment, but most of recurrent exerbation or expectant treatment invalid, still need to be treated surgically.

the cause of disease

Adhesive ileus is the congenital factor of intraperitoneal except minority, outside caused by congenital dysplasia or meconium peritonitis, is mostly acquired.Common cause is Abdominal inflammation, damage, hemorrhage, foreign body in abdominal cavity, and after being more common in abdominal operation or Abdominal inflammation, wherein the adhesion of abdominal postoperative is the ileac the first cause of disease at present, and abdominal cavity radiotherapy and intraperitoneal chemotherapy also can cause viscosity intestinal obstruction in addition.Operation on pelvis (as gynecilogical operation, appendectomy and Colon and rectum Post operation) and lower abdominal surgery especially easily produce intestinal adhesion and intestinal obstruction, and its reason is that pelvic cavity small intestinal is more free, and epigastrium small intestinal is then relatively fixing.But the patient of intestinal adhesion intestinal obstruction might not occur, and sticking together property intestinal obstruction does not necessarily represent abdominal cavity yet extensive, serious adhesion.Only have and make being fixed fettered by intestinal loop by generation obstacle, adhesion band two ends of intestinal contents when intestinal tube sticky point forms acute angle, or one group of intestinal loop adhesion is agglomerating, intestinal wall has cicatricial stricture just can cause adhesive ileus.

clinical manifestation

Namely the topmost clinical manifestation of adhesive ileus is the symptom of mechanical intestinal obstruction: stomachache, vomiting, abdominal distention, stopping exhaust defecation.

stomachache:during intestinal obstruction, because enterokinesia strengthens, often there is paroxysmal angina abdominis.There is gas to alter row in the normal self-induction abdomen of patient during stomachache outbreak, can see or lay one's hand on visible peristalsis visible intestinal peristalsis, hearing loud and sonorous borborygmus; If incomplete intestinal obstruction, when gas is by after blocking, pain suddenly alleviates or disappears; If mesentery is excessively by tractive, pain is persistence and paroxysmal increases the weight of; To late cases owing to blocking above intestinal tube overdistension, shrink weak, degree and the frequency of pain all alleviate; After there is enteroparalysis, stomachache changes persistence abdominal distention into.

vomiting:the frequency vomitted, vomiting amount and vomitus character are different with the height of region of obstruction.High intestinal obstruction vomiting occurs comparatively early, comparatively frequently, vomiting amount is more; When low small intestine obstruction and obstruction of colon, vomiting occurs more late, and number of times is also less, and vomiting amount is less, and vomitus often has excrement stink.

abdominal distention:abdominal distention is caused because of dilatation of intestine when blocking.Whether abdominal distention degree is because blocking completely and region of obstruction and different.Block more complete, position is lower, and abdominal distention is more obvious; Though sometimes block completely, because intestinal tube storage function is lost, vomiting is early frequent, also can not occur abdominal distention; If do not note this situation, can cause failing to pinpoint a disease in diagnosis, mistaken diagnosis.If block intestinal tube formation to close loop, often show unsymmetry abdominal distension, sometimes can lay one's hand on the intestinal tube of expansion at this place.

stop exhaust defecation:intestinal obstruction is obstructed because intestinal contents transports, and can not excrete, therefore anus stops exhaust defecation.But must be noted that, the intestinal contents of region of obstruction far-end still can send by under wriggling.Therefore, even if block completely, before these content emptyings, patient can continue there is exhaust defecation, just after emptying, just no longer includes exhaust defecation.Certainly, block in imperfection, exhaust defecation phenomenon can not disappear completely.In addition, ileac clinical symptoms also has water, electrolyte and acid base imbalance, meet strangulatedly to block, bowel necrosis, the performances such as shock, peritonitis and gastrointestinal hemorrhage can be there is.

Cure to treat takes fasting, gastrointestinal decompression, transfusion to maintain the method such as electrolyte, acid-base balance more, and serious symptom person's operative treatment, easily causes vicious cycle.

Summary of the invention

Technical problem to be solved by this invention is, provides that a kind of formula is simple, processing technology is easy, and the little and convenient drug administration of toxic and side effects, medicament is easy to manufacture, new drug with low cost.The present invention has ventilation intestine moistening, dispelling wind dampness removing, circulation of qi promoting scattered silt, sliding sharp effect of dredging and stagnating in intestinal that circulates, and cures mainly stomachache, vomiting, abdominal distention, stopping exhaust defecation; Reach the painful abdominal mass that disappears of regulating the flow of vital energy, the removing stagnancy of pathogens for obstruction of FU-organ, relieving spasm to stop pain, the merit of blood circulation promoting and blood stasis dispelling, ventilation intestine moistening, improve local blood circulation and metabolism, enhancing intestinal immunity, promote the object that function of intestinal canal recovers.The present invention adopts the Chinese crude drug of different properties, has carried out scientific compatibility, and can reach desirable therapeutic effect, safety, processing technology is easy, and toxic and side effects is little, and convenient drug administration, medicament is easy to manufacture, with low cost.

For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine preparation for the treatment of adhesive ileus, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Raphani 10-20 part, Bulbus Allii Fistulosi 10-20 part, Fructus Citri Sarcodactylis 10-20 part, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan 10-20 part, Radix Schefflerae Delavayi 10-20 part, Oleum Glycines 10-20 part, Radix Liriopes 10-20 part, Folium Crataegi 10-20 part, Flos Alangii 1-10 part, Herba Kalimeridis 1-10 part, Cortex Caryophylli 1-10 part, Semen Myristicae 1-10 part, Adeps Bovis seu Bubali 1-10 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 1-10 part, Flos Lonicerae 1-10 part, Herba Menthae 1-10 part, Fructus Quisqualis 1-10 part, Rhizoma Kaempferiae 1-10 part.

For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine preparation for the treatment of adhesive ileus, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Raphani 12-18 part, Bulbus Allii Fistulosi 12-18 part, Fructus Citri Sarcodactylis 12-18 part, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan 12-18 part, Radix Schefflerae Delavayi 12-18 part, Oleum Glycines 12-18 part, Radix Liriopes 12-18 part, Folium Crataegi 12-18 part, Flos Alangii 2-8 part, Herba Kalimeridis 2-8 part, Cortex Caryophylli 2-8 part, Semen Myristicae 2-8 part, Adeps Bovis seu Bubali 2-8 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 2-8 part, Flos Lonicerae 2-8 part, Herba Menthae 2-8 part, Fructus Quisqualis 2-8 part, Rhizoma Kaempferiae 2-8 part.

For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine preparation for the treatment of adhesive ileus, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Raphani 15 parts, Bulbus Allii Fistulosi 15 parts, Fructus Citri Sarcodactylis 15 parts, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan 15 parts, Radix Schefflerae Delavayi 15 parts, 15 parts, Oleum Glycines, Radix Liriopes 15 parts, Folium Crataegi 15 parts, Flos Alangii 5 parts, Herba Kalimeridis 5 parts, Cortex Caryophylli 5 parts, Semen Myristicae 5 parts, Adeps Bovis seu Bubali 5 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 5 parts, Flos Lonicerae 5 parts, Herba Menthae 5 parts, Fructus Quisqualis 5 parts, Rhizoma Kaempferiae 5 parts.

For solving the problems of the technologies described above, the present invention also provides a kind of preparation method for the treatment of the Chinese medicine preparation of adhesive ileus, and described Chinese medicine preparation dosage form is that the preparation method of capsule comprises:

A, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan, Folium Crataegi, Flos Alangii, Herba Kalimeridis, Flos Lonicerae, Herba Menthae are put into ethanol heating and refluxing extraction;

B, get surplus stock in above-mentioned side except Oleum Glycines again, add water heating and refluxing extraction;

C, above-mentioned two kinds of extracting solution to be merged, decompression recycling ethanol concentrated sucking filtration absorption, obtain crude drug; Add Oleum Glycines, canned.

In described step a, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan, Folium Crataegi, Flos Alangii, Herba Kalimeridis, Flos Lonicerae, Herba Menthae can be put into 10 times amount ethanol, heating and refluxing extraction 2 times, each 1 ~ 2 hour, extract active ingredient, 2 extracting solution be merged and leaves standstill;

In described step b, surplus stock is put into except Oleum Glycines 10 times of water gagings, heating and refluxing extraction 3 times, each 45 minutes ~ 1 hour, 3 extracting solution are merged and leaves standstill.

In described step c, can by the merging of above-mentioned two kinds of filtrates, decompression recycling ethanol to be concentrated into liquor strength be 0.4g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.06; Above-mentioned filtrate is the macroporous adsorptive resins of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicated powder; Again by Oleum Glycines, incapsulate together with the raw material medicated powder obtained.One time four, three times on the one.

For solving the problems of the technologies described above, the present invention also provides a kind of preparation method for the treatment of the Chinese medicine preparation of adhesive ileus, and described Chinese medicine preparation dosage form is that the preparation method of soup potus comprises:

By above-mentioned raw materials except Oleum Glycines, be placed in decoction pot, add 3 times of water gagings for the first time, soak 3 hours, decoct 20-30 minute, leach decocting liquid, second time adds 2 times of water gagings again, decocts 20-30 minute, twice decocting liquid mixing is added Oleum Glycines tune and namely obtains soup potus all afterwards.Be divided into two parts, every day is each portion sooner or later.

the property of medicine and the pharmacology of medicine selected by the present invention are respectively:

Radix Raphani:

Radix Raphani has another name called radix Raphani, sieve clothes.

[nature and flavor] Xin Gan is cool;

[return through ]enter lung, stomach warp;

[function cures mainly] removing food stagnancy is stagnant, heat of reducing phlegm, the therapeutic method to keep the adverse QI flowing downwards, alleviating distention in middle-JIAO, removing toxic substances.Control food stagnation distension, phlegmatic cough aphonia, spit blood, epistaxis, quenches one's thirst, dysentery, polarization headache.

1. " not Lu ": " main sharp the five internal organs, beneficial rational diet gas." 2. Tang Materia Medica: " loose clothes and big gun boil to be taken, the large therapeutic method to keep the adverse QI flowing downwards, and rapid digestion of food, removes accumulation of phlegm in the hypochondrium; Raw juice of smashing takes, and master quenches one's thirst."

3. the Meng numerous: " bad odor in the five internal organs, except the five internal organs apoplexy, is practiced in very sharp joint."

4. " four tones of standard Chinese pronunciation book on Chinese herbal medicine ": " ordinary person surfeits, and rawly chews just disappearing of pharynx, and also main lung is coughed haematemesis."

5. " feeding habits book on Chinese herbal medicine ": " sector-style gas, uncharm steam." " flower: improving eyesight."

6. " Japan hanako materia medica ": " energy stopping coughing and removing phlegm; Control consumptive lung disease to spit blood; Warming middle-JIAO, tonifying for the deficiency, control the thin cough of labor, and Carnis caprae seu ovis, Carassius auratus cooks it."

7. " daily book on Chinese herbal medicine ": " the chest stuffiness relieving diaphragm, sharp defecation.Prepared food it, reduce phlegm rapid digestion of food; Life eats it, and quench the thirst alleviating distention in middle-JIAO."

8. Wang Ying " food book on Chinese herbal medicine ": " clothes are smash in life, control fasting dysentery."

9. " book on Chinese herbal medicine can be compiled ": " kill fishy smell, control bean curd and amass."

10. " detailed outline ": " main acid regurgitation, eliminate indigestion is stagnant, alcoholic intoxication, and dissipating blood stasis blood, very imitates.End clothes control five types of stranguria; Ball clothes control nebulousurine; Decoct soup foot bath gas; Drink juice controls the inferior dysentery and aphonia, and sootiness is for extremely; Raw smash be coated with beat flutter, burn."

(11) " book on Chinese herbal medicine is looked for the truth ": " separate Radix Aconiti Lateralis Preparata poison."

(12) " occupy diet spectrum with breath ": " control cough with aphonia, all diseases of throat; Separate carbon monoxide poisoning, Fructus Solani melongenae poison.Ripe person's therapeutic method to keep the adverse QI flowing downwards and in, spleen reinforcing fortune food, born fluid, imperial wind and cold, foul leukorrhea, damp fetal cultivation blood."

Bulbus Allii Fistulosi:

[return through] lung; Stomach warp

[effect] is delivered; Activate yang; Removing toxic substances; Parasite killing

tAO Hong-Jing: Herba Alii fistulosi also has cold and heat, and white cold and cheerless heat, typhoid fever soup must not make green grass or young crops also.2. Zhang Yuansu: Herba Alii fistulosi stem "white expert" master disperses, with logical upper and lower yang-energy, the cold severe splitting headache therefore " living person's book " cures the wound, uses Nelumbo nucifera Gaertn bulbus Allii Fistulosi soupmaster's; Zhang Zhongjing controls SHAO YIN syndrome watery diarrhea with indigested food, cold in the interior and heat in the exterior, faint inverse faint pulse person, bai Tongtangmaster's, interior Bulbus Allii Fistulosi, if flushed face person, cold limbs Tonga Bulbus Allii Fistulosi, abdominal pain person, goes Bulbus Allii Fistulosi.The cloud of Cheng Wuji solution, the kidney being adverse to tryness, instant pungent to moisten it, the pungent temperature of Bulbus Allii Fistulosi, to activate yang gas also.3. " detailed outline ": Herba Alii fistulosi, the disease controlled, belongs to too yin, yang bright more, all gets the merit that it disperses ventilation.Ventilation event can be detoxified and treating blood disorders disease.Gas person, the general of blood also, live by gas general rule blood. incised woundknock damage, injured blood goes out, gnawing pains take no rest person, and king Liao " 101 side " Bulbus Allii Fistulosi, Saccharum Sinensis Roxb. decile grind envelope, and cloud pain stops immediately, more seamless scar also. folium Allii fistulosialso can use.Herba Alii fistulosi pipe blows salt and enters in beautiful stem again, controls urinary obstruction and turns the critical person of bladder.Remaining conventional, controlling several people must test.4. " Bencao Jingshu ": Herba Alii fistulosi, pungently to disperse, can expelling pathogenic factors from muscles, can lead to upper and lower yang-energy, therefore external looking angry strongly fragrant all cards, know and all lead it.Typhoid fever cold and heat, pathogen is also also; Apoplexy appearance swells, and wind heat is also strongly fragrant; Typhoid fever kindred pain, in the evil beginning also.Sore throat is obstructed, monarch mutually two fire superior in lung also Xin Liang disperses, obtain antiperspirant then fire from loose and sore throat is logical also. liver opening at eye, pathogenic heat in loose liver, therefore cloud returns order.Except liver pathogen, the loose then healthy energy of pathogen is led to, blood from tune and have the merit of antiabortive regulating the spleen and stomach profit the five internal organs.It says beneficial order eyeball, kills hundred poison of drug persons, be then the sharp key of pungent profit and hold concurrently dismiss ventilation power also.5. " medical center bun is wanted ": Herba Alii fistulosi, Tao Shi calls white cold and cheerless heat, and this but not so.But complete in the body that then works, root and bai Hangskin, green grass or young crops and point specially row reach flesh table, the upper head.Raw again with then layman, bathing then table is loose, ripe then keeps.6. a longevity chin or cheek: fresh Bulbus Allii Fistulosi, gently uses two, three pieces, heavy to five pieces, is good with soft and fine person, the continuous Herba Alii fistulosi of my Wu's meaning.Its sturdy person then says Bulbus Allii Ascalonici, and the turbid power of gas is thin, good not as soft and fine.Go blue or green with white, get that it is gently clear; Or Nelumbo nucifera Gaertn use, for its logical hundred arteries and veins of holding concurrently: if alone verdant stem, then stop up to dredge the strongly fragrant of liver network, from Bulbus Allii Fistulosi specially master disperse different.7. " herbal classic ": main typhoid fever cold and heat, perspireapoplexy, appearance swells.8. " not Lu ": cure the wound cold kindred pain, and sore throat is obstructed, antiabortive.9. the Meng numerous: get round by bribery; Only epistaxis, sharp defecation.10. " Japan hanako materia medica ": disease when controlling day row, have a headache fanatical, logical intestine and small intestine, cramp caused by acute vomiting and diarrhea and beautifully adorned globefish gas, beriberi, cardiac and abdominal pain, dizzy and only mental confusion due to heart disorder is vexed.11. " medication heart methods ": activate yang gas, disperses ailment said due to cold or exposure.12. li Gao: Zhi Yangming dysentery hematochezia.13. " daily books on Chinese herbal medicine ": can reach table and inner, antiabortive hemostasis.14. " book on Chinese herbal medicine covers bamboo fish trap ": snakebite, Lumbricus wound, and namely salt administration separates.15. " detailed outlines ": remove rheumatism, general pain paralysis, malnutrition due to parasitic infestation is pained, only adult Yang Tuo, insidious stomachache, and children's is coiled enteral and fished, married woman's gestation hematuria, logical milk, loose acute mastitis, and sharp tinnitus, is coated with dog poison.

Fructus Citri Sarcodactylis:

[meridian distribution of property and flavor] is pungent, bitter, sour, and temperature, returns liver, spleen, lung meridian.

[function cures mainly] tonifying liver warming the stomach, anti-nausea, the cold syndrome of the stomach that disappears expectorant, controls gastric qi pain, the only cold pain in face, and middle circulation of qi promoting.For stagnation of liver-QI and stomach-QI, leukorrhagia, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite is vomitted.

Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan:

[meridian distribution of property and flavor] is pungent, bitter, flat.

[effect] dispelling wind dampness removing, circulation of qi promoting dissipating blood stasis.For headache due to common cold, gastroenteritis, dysentery, abdominal distention; Treating swelling and pain by traumatic injury is controlled in external, wound hemorrhage, carbuncle sore tumefacting virus, worm venom, eczema, dermatitis.

Radix Schefflerae Delavayi:

[nature and flavor] mildly bitter flavor; Puckery; Property is put down

[function cures mainly] dispelling, collateral-activating; Strengthening the tendons and bones; Promoting flow of QI and blood.Main air pain of dampness syndrome; Soreness of waist and knee joint; Treating swelling and pain by traumatic injury; Breast side of body abdominal distention.

1. " Guizhou folk medicine ": " logical stool, detumescence poison.”

2. " the practical Chinese herbal medicine in Guangxi newly selects ": " dispelling, collateral-activating.Control fracture, dampen, rheumatic arthritis, lumbar muscle strain.”

Oleum Glycines:

[nature and flavor] are pungent; Sweet; Temperature [return through] large intestine channel

[effect classification] moisturizes medicine

[effect] loosening bowel to relieve constipation; Anthelmintic is detoxified

[textual criticism] is come from " compendium of Materia Medica".

[section belongs to classification] pulse family

[curing mainly] helminth is blocked; Constipation; Scabies Radix Liriopes

[another name] large Radix Ophiopogonis, native Radix Ophiopogonis, Chloranthus elatior, Radix Ophiopogonis;

[meridian distribution of property and flavor] sweet, micro-hardship, is slightly cold; GUIXIN, lung, stomach warp.

[function cures mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, chronic consumptive disease is coughed, and Tianjin wound is thirsty, and vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.

Rhizoma Kaempferiae:

Have another name called, Rhizoma Kaempferiae (" sea side "), three rely (" product converge with essence want "), Rhizoma Kaempferiae, mountain peppery (" detailed outline ") ， tri-Lai (" South Uietnam notes "), husky Rhizoma Zingiberis Recens (" south of the Five Ridges gather medicinal herbs record ");

[meridian distribution of property and flavor] temperature; Pungent; Return stomach warp

[function cures mainly] circulation of qi promoting warming middle-JIAO, help digestion, pain relieving.For chest and diaphragm distension, coldness and pain in the epigastrium, diet does not disappear.

Folium Crataegi:

[nature and flavor] acid; Flat;

[function cures mainly] has the function of promoting digestion and invigorating the stomach, activating blood circulation to dissipate blood stasis, convergence dysentery relieving.To meat amass phlegm retention, feeling of fullness acid regurgitation, dysenteryhemorrhoidal hamorrhage, lumbago hernia, puerperal after-pains, lochiorrhea, children's breast food stagnate etc., all effective in cure.Main dermatitis rhus, ulcer being unable to heal, hypertensionsick.

Flos Alangii:

[nature and flavor] acrid in the mouth; Property is put down; Mild toxicity

[return through] returns liver; Stomach warp

[function cures mainly] falls apart wind; Regulate the flow of vital energy; Pain relieving.Main wind syndrome of head headache; Chest and abdomen swelling and pain

Herba Kalimeridis:

[meridian distribution of property and flavor] acrid in the mouth, cold nature.Return liver, kidney, stomach, large intestine channel.

[effect] relieves internal heat anticancer, removing heat from blood scattered silt, clearing away heat-damp and promoting diuresis, reducing swelling and alleviating pain.

Energy heat-clearing and toxic substances removing, dissipating blood stasis stops blooding, and dampness removing, helps digestion, removing food stagnancy.For cat fever, cough, acute pharyngitis, tonsillitis, mumps, infectious hepatitis, stomach, duodenal ulcer, infantile malnutrition, enteritis, dysentery, spit blood, metrorrhagia, menoxenia; External is controlled furuncle and is swollen and ache, mastitis, traumatic hemorrhage; Dysentery or damp-heat diarrhea; Laryngopharynx swelling and pain, carbuncle skin infection; Heat in blood epistaxis, to have blood in stool; Jaundice due to damp-heat; Or edema, dysuria; Eating accumulation, distension and fullness in the abdomen.

Cortex Caryophylli:

[nature and flavor] " detailed outline ": pungent, temperature, nontoxic.

It is swollen that [function cures mainly-Cortex Caryophylli effect] controls invasion by pathogenic cold abdominal pain, has loose bowels, toothache.

1. " Haiyao Bencao, Oversea Materia Medica ": control toothache.

2. " detailed outline ": all diseases of trusted subordinate's cold air, the Fan family is with for Flos Caryophylli.

3. " herbal classic is met former ": control abdominal distention, feel sick, have loose bowels empty sliding, indigestion.

Semen Myristicae: warm in nature, acrid in the mouth, function warming the spleen stomach, circulation of qi promoting, helps digestion, Gu intestinal, be applicable to the abdominal distention that Deficiency and coldness of spleen and stomach causes, dyspepsia does not disappear, and lack of appetite is vomitted, the disease of diarrhea due to deficiency cold-dysentery.

Adeps Bovis seu Bubali:

Acrid in the mouth, cool in nature, nontoxic, herb can be used as medicine, and has clearing away heat and expelling pathogen in the exterior, effect that regulating QI to expel dampness falls urine detumescence.

Clinically treat the diseases such as yellow cellulitis, heatstroke, heating, vomiting, acute gastroenteritis, stomachache for flu-prevention, its expelling cold and relieving exterior syndrome function is better than Herba Menthae. united States Department of Agriculture (USDA)" phytochemistry and plant species " background information show, Adeps Bovis seu Bubali contains more than 30 kind of antimicrobial compound, is a kind of potential natural antibiotics and medicine growth promoter.

All herbal medicine, can prevent influenza, control the diseases such as heatstroke, flu, headache heavy sensation of the body, stomachache, vomiting, chest and diaphragm distension, vapour lock dyspepsia, food stagnation of child abdominal distention, diarrhoea, menorrhagia, bleeding not during menses, skin itching and edema, its cold expelling delivers function, is especially better than Herba Menthae.

Hericium erinaceus (Bull. Ex Fr.) Pers.:

[meridian distribution of property and flavor] is sweet, flat.

[function cures mainly] sharp the five internal organs are aid digestion.Cure mainly dyspepsia, neurasthenia, physical weakness.. " Xinhua's book on Chinese herbal medicine outline ": herb: sweet in the mouth, property is put down.Favourable the five internal organs, aid digestion, nourishing, the function such as anticancer.

Flos Lonicerae:

[nature and flavor] property is sweet, cold;

[function] has heat clearing away, removing toxic substances, antiinflammatory, antibacterial effect.Compendium of Material Medica is carried " Flos Lonicerae, is good at removing toxic substances, therefore controls carbuncle, toxic swelling, skin ulcer tinea ... ".Since ancient times, Flos Lonicerae is usually used in heat-clearing and toxic substances removing, the heating for the treatment of epidemic febrile disease, toxic-heat and blood stasis, the diseases such as carbuncle and ulcer, also for anemopyretic cold, and the diseases such as bronchitis.Modern pharmacological research shows, Flos Lonicerae has the effect such as antibacterial, antiviral, antiinflammatory, antipyretic, immunity moderation.

The loose poison of heat clearing away, Compendium of Material Medica is carried " Flos Lonicerae, is good at removing toxic substances, therefore controls carbuncle, toxic swelling, skin ulcer tinea ... ".Since ancient times, Flos Lonicerae is usually used in heat-clearing and toxic substances removing, the heating for the treatment of epidemic febrile disease, toxic-heat and blood stasis, the diseases such as carbuncle and ulcer.Modern pharmacological research shows, Flos Lonicerae has the effect traditional Chinese medical science such as antibacterial, antiviral, antiinflammatory, antipyretic, immunity moderation and thinks, Flos Lonicerae is cold in nature, sweet in the mouth, gas flat, has effect of heat-clearing and toxic substances removing, can treat the disease such as pyretic toxicity abscess, carbuncle furuncle.And have the loose effect of a surname concurrently.Flos Lonicerae antipyretic and antidote functions is quite strong.Flos Lonicerae can delay the pathological changes effect of Respirovirus to cell, is the representative medicine of heat-clearing and toxic substances removing, and pyretic toxicity essence is except containing multiple pathogenic microorganism, and microbial toxin also accounts for critical positions.Caused by the endotoxin that Flos Lonicerae preparation lumbar injection obviously can reduce bacillus pyocyaneus, the leukocyte count of rabbit declines, and deviation to the left phenomenon etc. has obvious antagonism.

Herba Menthae:

[meridian distribution of property and flavor] is cool in nature, acrid in the mouth;

The effect of [function] irritation causes trachea to produce new secretion, and makes the mucus of stiff be easy to get rid of, therefore has the effect of eliminating the phlegm, sterilizing.

It is one of Chinese conventional Chinese medicine.It is pungent cool property sweating antipyretic medicine, controls influenza, headache, conjunctival congestion, fever of the body, throat, dental bed the disease such as to swell and ache.Place with can training the mind dysmenorrhoea, skin pruritus, erythra and eczema etc.The Herba Menthae of light friend Greenhouse Fruit Picking is again the fresh vegetable on dining table in the Spring Festival.Clearly good to eat.Usually with Herba Menthae for tea, clear away heart-fire improving eyesight.Herba Menthae has extremely strong sterilization antibacterial action, often drinks its energy preventing viral flu, oral disease, makes breath freshening.With mint teajuice is gargled, and can prevent halitosis.Steam face with mint tea mist, also have the effect of shrinking pore.Apply by the blade steeping tea and can feel refrigerant on eyes, can eyestrain be removed.It is said and can be used for the another name that Herba Menthae also has " eyes grass " treating ophthalmic.

Fructus Quisqualis:

[meridian distribution of property and flavor] sweet in the mouth warm in nature, enters spleen, stomach, large intestine channel,

Effect of [effect] tool parasite killing, removing food stagnancy, spleen invigorating.Its sweet temperature is the temperature of gentleness, and different non-warm-dryness syndrome is comparable, therefore can help the automation of diet, and dredges in intestinal stagnant, and is rich in fat liquid, so sliding profit circulation.Semen Torreyae:

[nature and flavor] are sweet, flat.1. " herbal classic ": " sweet in the mouth, temperature." 2. " not Lu ": " be poisonous." 3. " a thousand pieces of gold dietetic therapy ": " sweet in the mouth is put down puckery, nontoxic."

[return through] enters lung, stomach, large intestine channel.1. " Bencao Jingshu ": " lunar, Yangming Channel of starting with." 2. " book on Chinese herbal medicine is newly organized ": " enters stomach, spleen, large intestine channel, enters lung again."

[function cures mainly] parasite killing, removing food stagnancy, moisturizes.Control abdominal pain due to worm stagnation, infantile malnutrition, cough caused by dryness, constipation, hemorrhoid.1. " herbal classic ": " pathogen in main abdomen, go three worms, Serpentis stings." 2. " not Lu ": " main five hemorrhoid." 3. TAO Hong-Jing: " is treated very little white." 4. the Meng numerous: " makes us eating, and rapid digestion of food, helps muscles and bones, and field headquarters is defended, improving eyesight." 5. " daily book on Chinese herbal medicine ": " kills greatly interventral small worm, children's's Huang is thin, and namely what have malnutrition due to parasitic infestation person to eat in abdomen heals.Under being with again shell to chew carefully food, expectorant." 6. " raw chief editor ": " controls cough, nebulousurine, supporing yang road." 7. essentials of Matea Medica: " lung moistening, parasite killing." 8. " herbal classic is met former ": " with fructus Quisqualissame merit." 9. " book on Chinese herbal medicine is new again ": " controls lung-fire, and spleen invigorating soil, QI invigorating is reduced phlegm, and cough-relieving is coughed, and surely breathes out to breathe heavily, eliminating blood stasis to promote regeneration of blood."

For solving the problems of the technologies described above, the present invention also provides a kind of dosage form for the treatment of the Chinese medicine preparation of adhesive ileus, and pharmaceutical dosage form can also be: sugar coated tablet, film coated tablet, enteric coated tablet, oral liquid, granule, electuary, powder, sublimed preparation, solution, suppository, plaster, syrup.

detailed description of the invention:

embodiment 1, formula:radix Raphani 10g, Bulbus Allii Fistulosi 10g, Fructus Citri Sarcodactylis 10g, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan 10g, Radix Schefflerae Delavayi 10g, Oleum Glycines 10g, Radix Liriopes 10g, Folium Crataegi 10g, Flos Alangii 1g, Herba Kalimeridis 1g, Cortex Caryophylli 1g, Semen Myristicae 1g, Adeps Bovis seu Bubali 1g, Hericium erinaceus (Bull. Ex Fr.) Pers. 1g, Flos Lonicerae 1g, Herba Menthae 1g, Fructus Quisqualis 1g, Rhizoma Kaempferiae 1g;

Preparation method:

Step a, can put into 10 times amount ethanol by Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan, Folium Crataegi, Flos Alangii, Herba Kalimeridis, Flos Lonicerae, Herba Menthae, heating and refluxing extraction 2 times, each 1 ~ 2 hour, extracts active ingredient, is merged by 2 extracting solution and leaves standstill;

Step b, puts into 10 times of water gagings except Oleum Glycines by surplus stock, heating and refluxing extraction 3 times, each 45 minutes ~ 1 hour, is merged by 3 extracting solution and leaves standstill;

Step c, can by the merging of above-mentioned two kinds of filtrates, decompression recycling ethanol to be concentrated into liquor strength be 0.4g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.06; Above-mentioned filtrate is the macroporous adsorptive resins of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicated powder; Again by Oleum Glycines, incapsulate together with the raw material medicated powder obtained.One time four, three times on the one.

Treatment model case:

Patient 38 years old, patient: grandson so-and-so, more than bad resistive appendicitis, periappendiceal abscess Post operation May, suffer from intestinal adhesion, patient's umbilicus Zhou Mingxian tenderness, without rebound tenderness, without enclosed mass, abdominal distention is not relaxed, nausea and vomiting.Oral medicine of the present invention 3 days, free movement of the bowels, after 1 week, all diseases disappear.

embodiment 2, formula:radix Raphani 12g, Bulbus Allii Fistulosi 12g, Fructus Citri Sarcodactylis 12g, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan 12g, Radix Schefflerae Delavayi 12g, Oleum Glycines 12g, Radix Liriopes 12g, Folium Crataegi 12g, Flos Alangii 2g, Herba Kalimeridis 2g, Cortex Caryophylli 2g, Semen Myristicae 2g, Adeps Bovis seu Bubali 2g, Hericium erinaceus (Bull. Ex Fr.) Pers. 2g, Flos Lonicerae 2g, Herba Menthae 2g, Fructus Quisqualis 2g, Rhizoma Kaempferiae 2g;

Preparation method: by above-mentioned raw materials except Oleum Glycines, is placed in decoction pot, and first time adds 3 times of water gagings, soak 3 hours, decoct 20-30 minute, leach decocting liquid, second time adds 2 times of water gagings again, decocts 20-30 minute, twice decocting liquid mixing is added Oleum Glycines tune and namely obtains soup potus all afterwards.Be divided into two parts, every day is each portion sooner or later.

Treatment model case:

Patient Liu so-and-so, female, 35 years old, because of paroxysmal abdominal pain abdominal distention, non-defecation aerofluxus was admitted to hospital for 3 days.Readme before 1 year because of bilateral ovaries tumor, side Ovarian Tumors with Twisted Pedicle hospitalisation for surgery.Health check-up: full abdominal pressure pain, auscultation borborygmus is obviously hyperfunction, and x-ray fluoroscopy jejunum and ileum has fluid level, is diagnosed as intestinal adhesion companion intestinal obstruction.Oral medicine of the present invention is after 4 days, and symptom is improved, and starts defecation, and after 1 week, all diseases disappear, and adhere to medication 15 days, consolidate curative effect, prevention of recurrence.Follow up a case by regular visits to and have no recurrence in more than 2 years.

embodiment 3, formula:radix Raphani 15g, Bulbus Allii Fistulosi 15g, Fructus Citri Sarcodactylis 15g, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan 15g, Radix Schefflerae Delavayi 15g, Oleum Glycines 15g, Radix Liriopes 15g, Folium Crataegi 15g, Flos Alangii 5g, Herba Kalimeridis 5g, Cortex Caryophylli 5g, Semen Myristicae 5g, Adeps Bovis seu Bubali 5g, Hericium erinaceus (Bull. Ex Fr.) Pers. 5g, Flos Lonicerae 5g, Herba Menthae 5g, Fructus Quisqualis 5g, Rhizoma Kaempferiae 5g;

Preparation method: by above-mentioned raw materials except Oleum Glycines, is placed in decoction pot, and first time adds 3 times of water gagings, soak 3 hours, decoct 20-30 minute, leach decocting liquid, second time adds 2 times of water gagings again, decocts 20-30 minute, twice decocting liquid mixing is added Oleum Glycines tune and namely obtains soup potus all afterwards.Be divided into two parts, every day is each portion sooner or later.

Treatment model case: patient 45 years old, because of traffic accident rupture of spleen, enterorrhexis operative treatment, operation is smoothly, without exception when leaving hospital.After 1 year, patient is because of eating and drinking without temperance sense paroxysmal abdominal pain, nausea and vomiting, abdominal tympanites, and not defecation also not aerofluxus, is diagnosed as adhesive ileus in conjunction with medical history.Oral medicine of the present invention is after 3 days, and symptom is improved, and starts defecation, and after 1 week, all diseases disappear, and adhere to medication 15 days, consolidate same curative effect, prevention of recurrence.

embodiment 4, formula: Radix Raphani 20g, Bulbus Allii Fistulosi 20g, Fructus Citri Sarcodactylis 20g, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan 20g, Radix Schefflerae Delavayi 20g, Oleum Glycines 20g, Radix Liriopes 20g, Folium Crataegi 20g, Flos Alangii 10g, Herba Kalimeridis 10g, Cortex Caryophylli 10g, Semen Myristicae 10g, Adeps Bovis seu Bubali 10g, Hericium erinaceus (Bull. Ex Fr.) Pers. 10g, Flos Lonicerae 10g, Herba Menthae 10g, Fructus Quisqualis 10g, Rhizoma Kaempferiae 10g;

Preparation method: by above-mentioned raw materials except Oleum Glycines, is placed in decoction pot, and first time adds 3 times of water gagings, soak 3 hours, decoct 20-30 minute, leach decocting liquid, second time adds 2 times of water gagings again, decocts 20-30 minute, twice decocting liquid mixing is added Oleum Glycines tune and namely obtains soup potus all afterwards.Be divided into two parts, every day is each portion sooner or later.

Treatment model case: patient 25 years old, after caesarean operation, the 3rd day sense paroxysmal abdominal pain, abdominal tympanites, not defecation also not aerofluxus, is diagnosed as adhesive ileus.Oral medicine of the present invention is after 1 day, and symptom is improved, and starts defecation, and after 1 week, all diseases disappear, and adhere to medication 15 days, consolidate same curative effect, prevention of recurrence.

Pharmacological toxicity is tested

1, acute toxicity test

Application mice carries out acute toxicity testing and shows: the Traditional Chinese medicine preparation capsule agent of the present invention of Mouse oral gavage, under 488.8g crude drug/kg dosage, after administration, mice occurs that light activity reduces, 1 hours recovers normal, Continuous Observation 7 days after administration, none animal dead, its overall health of patients, diet, take the photograph water, urine and body weight increase all normal, experimental result shows: the maximum dosage-feeding of Mouse oral gavage Traditional Chinese medicine preparation capsule agent of the present invention is 488.8g crude drug/kg/d (LD 50 > 488.8g crude drug/kg).Chinese medicine preparation clinical application every day total amount of the present invention is 0.1g crude drug/kg/d; By weighing machine, the dosis tolerata of mouse stomach Chinese medicine preparation of the present invention is 4888 times of clinical patient.Point out this medicine acute toxicity low, clinical drug safety.

2, long term toxicity test

Select SD rat, give the Chinese medicine preparation soup potus of the present invention of variable concentrations (18.0,6.0,2.0g crude drug/kg), every day gavage once, continuous 90 days, within after last administration 24 hours, respectively group is alive kills 1/2 animal (male and female half and half), and all the other 1/2 animals continue observations 2 weeks rear living and kill.Duration of test observes outward appearance, general behavior, food ration, the body weight change of animal, within after administration 90 days, within 2 weeks, carries out the index checking such as hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology with drug withdrawal.Result of the test shows: invention formulation is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and matched group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range, without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, rat is had no significant effect in high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) administration in continuous 90 days according to result of the test Chinese medicine preparation of the present invention, without clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention higher.

3, animal local excitation test:

The allergic reaction on guinea pigs of Tablets and capsule Rat-rectum medication irritation test.Result shows: skin anaphylactic test, high dose group 0.8g (medicated powder)/kg, low dose group 0.1g (medicated powder)/kg, be equivalent to 20 times, 2.5 times that intend clinical people's consumption [0.04g (medicated powder)/kg] respectively, through percutaneous drug delivery, be showed no animal and produce allergy; Rectal application irritation test high dose group 5.0g (medicated powder)/kg, low dose group 3.2g (medicated powder)/kg, be equivalent to 125,80 times that intend clinical people's consumption respectively, mucous membrane of rectum is observed all without phenomenons such as hyperemia, edema in official hour, histopathologic examination compares no significant difference with blank group, have no and occur obvious irritative response, often organize its overall health of patients of Some Animals of retention, body weight, breathing, circulation, central nervous system and extremity are movable, equal Non Apparent Abnormality reaction.

Clinical data

1 object and method

1.1 subject patient 200 examples, are divided into matched group 5O example at random, man 35 example, female 15 example, treatment group 150 example, man 90 example, female 60 example, two groups of ages all 18-80 year between.

1.2 diagnostic criterias are with reference to clinical manifestation:

The symptom of intestinal adhesion and adhesive ileus: umbilicus Zhou Mingxian tenderness, without rebound tenderness, without enclosed mass.Abdominal distention is not relaxed, stomachache, nausea and vomiting, not defecation also not aerofluxus.Percussive tympany, x x ray fluoroscopy x, jejunum and ileum has fluid level.

1.3 Therapeutic Method treatment groups: take capsule of the present invention, natural gift three times are taken, 4 tablets/time, seven days courses for the treatment of.

Matched group: twice maintenance electrolyte of infusing every day, fasting gives gastrointestinal decompression;

1.4 efficacy assessment standards (1) clinical recovery: the clinical symptoms such as abdominal distention intestinal obstruction, sign disappear, functional activity recovers normal, checks that indices recovers.

(2) effective: symptom obviously alleviates.(3) effective: symptom alleviates slightly.(4) invalid: clinical symptoms, sign are without change.

I.5 statistical procedures uses SPSS 12.0 software to carry out statistical analysis, and ask that mean compares employing one factor analysis of variance for each group, group is asked and compared employing between two.Inspection.P<0.05 is that difference has significance.

2 results

Matched group recovery from illness 22 example, accounts for 44%; Effective 11 examples, account for 22%; Effective 8 examples, account for 16%; No effect 9, accounts for 18%, total effective rate 82%.Treatment group recovery from illness 98 example, accounts for 65.33%; Effective 32 examples, account for 21.33%; Effective 15 examples, account for 10%; Invalid 5 examples, account for 3.33%.Total effective rate accounts for 96.66%.Significance (P<O.05) is had through checking two groups of differences.

All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.

The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (6)

1. treat the Chinese medicine preparation of adhesive ileus for one kind, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Raphani 10-20 part, Bulbus Allii Fistulosi 10-20 part, Fructus Citri Sarcodactylis 10-20 part, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan 10-20 part, Radix Schefflerae Delavayi 10-20 part, Oleum Glycines 10-20 part, Radix Liriopes 10-20 part, Folium Crataegi 10-20 part, Flos Alangii 1-10 part, Herba Kalimeridis 1-10 part, Cortex Caryophylli 1-10 part, Semen Myristicae 1-10 part, Adeps Bovis seu Bubali 1-10 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 1-10 part, Flos Lonicerae 1-10 part, Herba Menthae 1-10 part, Fructus Quisqualis 1-10 part, Rhizoma Kaempferiae 1-10 part.

2. a kind of Chinese medicine preparation for the treatment of adhesive ileus according to claim 1, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Raphani 12-18 part, Bulbus Allii Fistulosi 12-18 part, Fructus Citri Sarcodactylis 12-18 part, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan 12-18 part, Radix Schefflerae Delavayi 12-18 part, Oleum Glycines 12-18 part, Radix Liriopes 12-18 part, Folium Crataegi 12-18 part, Flos Alangii 2-8 part, Herba Kalimeridis 2-8 part, Cortex Caryophylli 2-8 part, Semen Myristicae 2-8 part, Adeps Bovis seu Bubali 2-8 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 2-8 part, Flos Lonicerae 2-8 part, Herba Menthae 2-8 part, Fructus Quisqualis 2-8 part, Rhizoma Kaempferiae 2-8 part.

3. a kind of Chinese medicine preparation for the treatment of adhesive ileus according to claim 2, it is characterized in that, in described Chinese medicine preparation, the ratio of weight and number of various crude drug is: Radix Raphani 15 parts, Bulbus Allii Fistulosi 15 parts, Fructus Citri Sarcodactylis 15 parts, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan 15 parts, Radix Schefflerae Delavayi 15 parts, 15 parts, Oleum Glycines, Radix Liriopes 15 parts, Folium Crataegi 15 parts, Flos Alangii 5 parts, Herba Kalimeridis 5 parts, Cortex Caryophylli 5 parts, Semen Myristicae 5 parts, Adeps Bovis seu Bubali 5 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 5 parts, Flos Lonicerae 5 parts, Herba Menthae 5 parts, Fructus Quisqualis 5 parts, Rhizoma Kaempferiae 5 parts.

4. a kind of Chinese medicine preparation for the treatment of adhesive ileus according to claim 1-3 any one is characterized in that, described Chinese medicine preparation dosage form is that the preparation method of capsule comprises:

A, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan, Folium Crataegi, Flos Alangii, Herba Kalimeridis, Flos Lonicerae, Herba Menthae are put into ethanol heating and refluxing extraction;

B, get surplus stock in above-mentioned side except Oleum Glycines again, add water heating and refluxing extraction;

C, above-mentioned two kinds of extracting solution to be merged, decompression recycling ethanol concentrated sucking filtration absorption, obtain crude drug; Add Oleum Glycines, canned.

5. preparation method according to claim 4, is characterized in that:

In described step a, Isodonpubescens (Hemsl.) C. Y. Wuet Hsuan, Folium Crataegi, Flos Alangii, Herba Kalimeridis, Flos Lonicerae, Herba Menthae can be put into 10 times amount ethanol, heating and refluxing extraction 2 times, each 1 ~ 2 hour, extract active ingredient, 2 extracting solution be merged and leaves standstill;

In described step b, surplus stock is put into except Oleum Glycines 10 times of water gagings, heating and refluxing extraction 3 times, each 45 minutes ~ 1 hour, 3 extracting solution are merged and leaves standstill;

In described step c, can by the merging of above-mentioned two kinds of filtrates, decompression recycling ethanol to be concentrated into liquor strength be 0.4g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.06; Above-mentioned filtrate is the macroporous adsorptive resins of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicated powder; Again by Oleum Glycines, incapsulate together with the raw material medicated powder obtained.

6. a kind of Chinese medicine preparation for the treatment of adhesive ileus according to claim 1-3 any one, is characterized in that: described Chinese medicine preparation dosage form is that the preparation method of soup potus comprises:

By above-mentioned raw materials except Oleum Glycines, be placed in decoction pot, first time adds 3 times of water gagings, soaks 3 hours, decocts 20-30 minute, leach decocting liquid, second time adds 2 times of water gagings again, decocts 20-30 minute, twice decocting liquid mixing is added Oleum Glycines tune and namely obtains soup potus all afterwards, be divided into two parts, every day is each portion sooner or later.