CN105166546A - Milk cow compound feed and making method thereof - Google Patents

Milk cow compound feed and making method thereof Download PDF

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CN105166546A
CN105166546A CN201510617410.5A CN201510617410A CN105166546A CN 105166546 A CN105166546 A CN 105166546A CN 201510617410 A CN201510617410 A CN 201510617410A CN 105166546 A CN105166546 A CN 105166546A
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weight
milk cow
chinese medicine
radix
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黄河
李鑫
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Shandong New Hope Liuhe Group Co Ltd
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Shandong New Hope Liuhe Group Co Ltd
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Abstract

The invention discloses milk cow compound feed and a making method thereof. The feed is made from corn flour, shell powder, cottonseed cakes, bran, bone meal, bean cakes, pumpkin, loquat, lotus roots, carrots, dark plum fruits, bananas, kelp, a vitamin pre-mixing material and a microelement pre-mixing material. The making method comprises the following steps of crushing, ingredient blending and granulating. The milk cow compound feed has the advantages that the feed contains traditional Chinese medicine additives with the effects of clearing away heat and toxic materials, eliminating carbuncles and relieving swelling and promoting blood circulation to remove blood stasis, can enhance the resistivity and has the advantages of being short in treatment course, good in curative effect, free of drug residues, low in cost and the like, the traditional Chinese medicine additives are matched and interact with raw materials of other feed, the mastitis of milk cow can be treated, and the nutritive requirement of the milk cow can also be met.

Description

A kind of milk cow mixed feed and preparation method thereof
Technical field
The present invention relates to animal and fowl fodder, particularly a kind of milk cow mixed feed and preparation method thereof.
Background technology
Mastadenitis of cow refers to the inflammation of the mammary gland caused by the various cause of disease, and its main feature is milk generation physicochemical property and bacteriology change, breast tissue generation Pathologic changes.Clinical mastitis is easily made a definite diagnosis, but because most of case (subclinical mastitis) hand palpation mammary gland is difficult to note abnormalities, with the naked eye check that milk is also difficult to observe pathologic change, so there is now people that mastitis is defined as a kind of disease that the white blood cell count(WBC) infected in mammary gland milk significantly increases, define more accurately, determine according to its cause of disease.
The cause of disease
1, environmental management factor: environmental condition is as muddy in cowshed, ox bed and sports ground can't bear, and around ox body and mammary gland, incrustation is too many, and sanitary condition is too poor, too high (more than 36 DEG C) of temperature or too low (less than-5 DEG C) etc.Milking conditions does not meet lactation physiological requirement, as too high in negative pressure of vacuum, too low, and unsuitable scouring mammary gland and embarkation are milked.
2, pathogenic infection: up to the present, people have isolated 150 kinds of pathogenic microorganisms from cow mammary gland tissue, and modal have 23 kinds, wherein 14 kinds, bacterium, mycoplasma 2 kinds, fungi and 7 kinds, virus.What wherein the incidence of disease was the highest is staphylococcus aureus, Escherichia coli, streptococcus, and mycoplasma, the fungus-caused mastitis incidence of disease rise year by year in recent years.
3, ox oneself factor: be in lactation and contain phase or the too high milk cow of milk production, body energy is in negative balance resistance, aged ox, polyembryony time ox relative incidence rate are high.
4, secondary factors: the author finds the babesiasis of milk cow in clinical treatment in recent years, also can become the paathogenic factor of mastadenitis of cow, and treatment is got up also very difficult.There is PNI also can cause mastitis occurs again.For this reason, first protopathy should be controlled after Secondary cases mastitis being made a definite diagnosis.
These factors above-mentioned, all can damage or reduce the physiological resistivity of mammary gland, cause pathogenic microorganism invasion and grow breeding.Usually the microorganism of mastitis is caused to have streptococcus, staphylococcus, corynebacterium pyogenes, Pseudomonas aeruginosa, necrobacillus, proteus, promise long starlike bacterium, Escherichia coli, mycobacterium, Mycoplasma etc. multiple.Pathogen such as tubercle bacillus, the actinomyces etc. of some infectious disease also can cause mastitis.Wherein modal is streptococcus, staphylococcus and Escherichia coli and suppurative corynebacteria.
The kind of mastitis and symptom
(1) serosity mastitis: the feature of serosity mastitis is that mammary gland is congested, between subcutaneous and leaf, connective tissue has serous effusion and leucocyte, often occurs in the cow initial a few days in postpartum.The part swelling of intramammary infection is rubescent, has heat and pain.That touches is hard solid, and the enlargement of mammary gland superior gluteal lymph node, the output of milk reduces.Mild person, initial stage milk change is little, later rarefaction with floccule gradually, by many less.The swelling of severe person's mammary gland is very large, and the output of milk reduces, and body temperature raises, and diet subtracts greatly even absolutely useless, down in spirits.
(2) Catarrhal mastitis: the pathological characters of Catarrhal mastitis, mainly acinus, glandular tube, ductus lactiferi and newborn pond glandular epithelium and other epithelial cells strip off and sex change, its leucocyte oozed out and the epithelial deposits that comes off are on epithelial surface, because inflammation only relates to epithelium top layer, therefore claim Catarrhal mastitis.Due to the difference of diseased region, symptom is also different.Acinus catarrh is the limitation inflammation of indivedual leaflet or several leaflet, the milk extruded by inflammation part, in clear rare water sample, containing cotton-shaped grumeleuse.As inflammation, affected part temperature increases, pain of having milked, and has body temperature to raise the constitutional symptom such as (being no more than 40.5 DEG C), anorexia.Ductus lactiferi and newborn pond catarrh, affected part is congested, swelling, and cotton-shaped grumeleuse is contained in Ruzhong.Grumeleuse can block ductus lactiferi makes tube chamber expand, and outside can touch dough tubercle or feel fluctuation, and its cotton-shaped grumeleuse can block nipple, is not easily extruded.Along with lesion milk squeezes to the greatest extent, after the milk extruded can transfer to normally.
(3) suppurative mastitis: suppurative mastitis is divided into suppurative Catarrhal mastitis, mammary gland swelling and mammary gland cellulitis etc. several.Clinically all with the heating of affected part initial stage, swelling, pain, the later stage suppurates, and the body temperature that occurs together raises, and mammary nodes enlargement, diet reduces, and down in spirits is feature.After the acute stage of suppurative Catarrhal mastitis, the degree of inflammation of affected part alleviates gradually, and swelling is reduced, spirit and diet normal.But affected tissue sex change, newborn lobar atrophy, milk is thin in yellow or faint yellow.
(4) fibrin mastitis: this is a kind of extremely serious acute mastitis, is characterized in that Fibrin exudation arrives the mucous membrane surface of newborn pond and ductus lactiferi, or is deposited in mammary gland essence depths, can the necrosis of secondary mammary gland or purulence liquefaction.Usually developed by Catarrhal mastitis, affected part is warm, swollen, bitterly serious, the enlargement of mammary gland superior gluteal lymph node.During palpation breast pond base portion, crepitus can be heard.With constitutional symptom, body temperature is elevated to 40 ~ 41 DEG C, and diet goes down or gives up absolutely.
Each state all adopts multiple method to carry out diagnosis of milk cow mastitis.Generally adopt with the following method in China:
Chemical analysis method (CMT): this method generally adopts in China, and reagent all domesticizes, can be carried out on ox body side, be judged the weight of subclinical mastitis by the condensation degree of milk.
Physical testing method: milk conductivity test, it is positive and negative and suspicious that the method only can show subclinical mastitis, can not show the degree of inflammation, and China successively produces 3 kinds of model mastitis detectors.
Body cell detection method: look into somatic number in milk sample by body cell instrument, China is decided to be the positive more than 5,000,000/milliliter.
Doctor trained in Western medicine medication is based on anti-inflammation, antipyretic-antalgic, and it is auxiliary for improving blood circulation.First mid-term should bactericidal antiphlogistic, selects that consumption is little, curative effect is high and lasting responsive medicine.Trouble for serious symptom is raiseeed, and first take stopgap measures help, adopts fluid transport therapy, selects those to diffuse into the fastest medicine of mammary alveolar.Western medical treatment scheme, medicine is all limited, do not reach desirable result for the treatment of, and treatment cost is higher.
The traditional Chinese medical science thinks the pathogenic factor of mastitis, how by wet nurse's nipple deformity, cave in, be difficult to lactation or milk and be difficult to inhale empty manylyly and newbornly, cause galactostasis, lose breast accumulation and make purulence; In addition lactation feelings will internal injury liver-qi depression, liver dysfunction bar reaches, and makes milk discharge smooth or eating and drinking without temperance, positive bright accumulated heat, and cause channels and collaterals and block, heat symptoms caused by an exopathgen are pented up for purulence; Also due to nipple ulceration, can infect evil poison, enter inner heat-transmission, meat corruption becomes purulence.But Chinese medicine mastadenitis of cow not only has the antiviral of western modern medicine waits effect, also there is clearing heat and detoxicating, the carbuncle that disappears loose swollen, promoting blood circulation and removing blood stasis, improve the immunity of organisms of milk cow, selected natural Chinese traditional medicines material, make drug effect directly arrive focus, the course for the treatment of is shorter, curative effect is better, prolonged application has no drug resistance, drug residue free, and cost price is cheap.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of mixed feed of Chinese medicine additive containing being used for the treatment of mastadenitis of cow, the Feed Energy containing this Chinese medicine additive is adopted to overcome the various defects of Chinese medicine of the prior art and Western medicine, there is clearing heat and detoxicating, the carbuncle that disappears to fall apart effect swollen, promoting blood circulation and removing blood stasis, can strengthen its resistivity, the course for the treatment of is shorter, and curative effect is better, prolonged application has no drug resistance, drug residue free, cost price is cheap, can effective symptom management.
In order to realize foregoing invention object, the invention provides a kind of milk cow mixed feed, it is characterized in that, described feed comprises following raw material: corn flour, oyster shell whiting, cottonseed cake, wheat bran, bone meal, soya-bean cake, pumpkin, loquat, lotus rhizome, carrot, dark plum, banana, sea-tangle, vitamin premix and microelement pre-mix material.
In described feed, the parts by weight of each raw material are: corn flour 30-50 weight portion, oyster shell whiting 10-20 weight portion, cottonseed cake 20-30 weight portion, wheat bran 30-40 weight portion, bone meal 10-15 weight portion, soya-bean cake 20-25 weight portion, pumpkin 15-25 weight portion, loquat 10-15 weight portion, lotus rhizome 10-20 weight portion, carrot 20-30 weight portion, dark plum 10-15 weight portion, banana 10-20 weight portion, sea-tangle 10-25 weight portion, vitamin premix 0.1-0.5 weight portion and microelement pre-mix material 0.1-0.5 weight portion.
Described feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: corn flour 30-50 weight portion, oyster shell whiting 10-20 weight portion, cottonseed cake 20-30 weight portion, wheat bran 30-40 weight portion, bone meal 10-15 weight portion, soya-bean cake 20-25 weight portion, pumpkin 15-25 weight portion, loquat 10-15 weight portion, lotus rhizome 10-20 weight portion, carrot 20-30 weight portion, dark plum 10-15 weight portion, banana 10-20 weight portion, sea-tangle 10-25 weight portion, vitamin premix 0.1-0.5 weight portion, microelement pre-mix material 0.1-0.5 weight portion and Chinese medicine additive 2-5 weight portion.
In described feed, the parts by weight of each raw material are: corn flour 40 weight portion, oyster shell whiting 15 weight portion, cottonseed cake 25 weight portion, wheat bran 35 weight portion, bone meal 12 weight portion, soya-bean cake 23 weight portion, pumpkin 19 weight portion, loquat 11 weight portion, lotus rhizome 16 weight portion, carrot 27 weight portion, dark plum 13 weight portion, banana 16 weight portion, sea-tangle 12 weight portion, vitamin premix 0.4 weight portion, microelement pre-mix material 0.3 weight portion and Chinese medicine additive 4 weight portion.
Described Chinese medicine additive comprises following raw medicinal material: Ageratum conyzoides, trichosanthes seed, cordate houttuynia, hawksbill turtle, Dysosma versipellis, Ku Zhi, fin Ji, fern beanstalk, lyrate hemistepta herb, selfheal, caulis trachelospermi ,sri Lanka Pouzolzia Herb, amplexicaul swallowwort herb, honeysuckle, the capsule of weeping forsythia, spina gleditsiae, dandelion, silene aprica, Ficus lyrata, clematis armandi Francs, the seed of cowherb, Radix Rhapontici seu Radix Echinopsis, play both sides of the street, pangolin, the Radix Astragali, Radix Angelicae Sinensis, Radix Glycyrrhizae.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are: Ageratum conyzoides 10-18 weight portion, trichosanthes seed 20-28 weight portion, cordate houttuynia 15-23 weight portion, hawksbill turtle 10-18 weight portion, Dysosma versipellis 5-8 weight portion, Ku Zhi 10-16 weight portion, fin Ji 12-17 weight portion, fern beanstalk 11-19 weight portion, lyrate hemistepta herb 20-29 weight portion, selfheal 8-14 weight portion, caulis trachelospermi 13-18 weight portion ,sri Lanka Pouzolzia Herb 12-22 weight portion, amplexicaul swallowwort herb 16-28 weight portion, honeysuckle 15-19 weight portion, capsule of weeping forsythia 10-17 weight portion, spina gleditsiae 8-16 weight portion, dandelion 22-28 weight portion, silene aprica 11-17 weight portion, Ficus lyrata 16-25 weight portion, clematis armandi Francs 12-18 weight portion, seed of cowherb 14-17 weight portion, Radix Rhapontici seu Radix Echinopsis 12-19 weight portion, the 15-25 weight portion that plays both sides of the street, pangolin 10-16 weight portion, Radix Astragali 10-18 weight portion, Radix Angelicae Sinensis 18-25 weight portion and Radix Glycyrrhizae 15-26 weight portion.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are: Ageratum conyzoides 15 weight portion, trichosanthes seed 22 weight portion, cordate houttuynia 17 weight portion, hawksbill turtle 12 weight portion, Dysosma versipellis 6 weight portion, Ku Zhi 15 weight portion, fin Ji 13 weight portion, fern beanstalk 14 weight portion, lyrate hemistepta herb 26 weight portion, selfheal 13 weight portion, caulis trachelospermi 15 weight portion ,sri Lanka Pouzolzia Herb 20 weight portion, amplexicaul swallowwort herb 18 weight portion, honeysuckle 16 weight portion, the capsule of weeping forsythia 14 weight portion, spina gleditsiae 10 weight portion, dandelion 23 weight portion, silene aprica 12 weight portion, Ficus lyrata 17 weight portion, clematis armandi Francs 15 weight portion, the seed of cowherb 16 weight portion, Radix Rhapontici seu Radix Echinopsis 17 weight portion, 23 weight portions that play both sides of the street, pangolin 15 weight portion, the Radix Astragali 16 weight portion, Radix Angelicae Sinensis 21 weight portion and Radix Glycyrrhizae 22 weight portion.
In order to realize goal of the invention better, the present invention also provides a kind of mixed feed being used for the treatment of mastadenitis of cow, and it contains Chinese medicine additive, and the preparation method of Chinese medicine additive comprises the following steps:
The first step, mixes in proportion by described each raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, adds hot reflux 1 ~ 3 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 ~ 2 times to be again the ethanol of 85 ~ 95%, to add hot reflux 1 ~ 3 hour that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders, obtain Chinese medicine additive powder.
In order to realize goal of the invention better, the present invention also provides a kind of preparation method being used for the treatment of the mixed feed of mastadenitis of cow, and described preparation method comprises the following steps:
(1) destruction step: take cottonseed cake, soya-bean cake, pumpkin, loquat, lotus rhizome, carrot, dark plum, banana, sea-tangle by ratio of weight and the number of copies, drops into pulverizer and carries out Crushing of Ultrafine, crosses 1.0mm sieve after pulverizing;
(2) batching step: take corn flour, oyster shell whiting, wheat bran, bone meal, vitamin premix, microelement pre-mix material and Chinese medicine additive according to ratio of weight and number, pulverize with step (1) fine powder obtained to mix, drop into mixer, mix, incorporation time is 30-60s;
(3) granulation step: drop into granulator and granulate, pelleting temperature is 85 DEG C, makes its gelatinization degree reach more than 90%.
The invention has the beneficial effects as follows: feed of the present invention contains and has clearing heat and detoxicating, the carbuncle that disappears and to fall apart Chinese medicine additive that is swollen, function of promoting blood circulation to disperse blood clots, its resistivity can be strengthened, there is the course for the treatment of shorter, curative effect is better, drug residue free, the advantages such as cost price is cheap, Chinese medicine additive and other feedstuffs cooperatively interact, interact, can not only mastadenitis of cow be treated, the nutritional need of ox can also be met.
Detailed description of the invention
Chinese medicine additive of the present invention is followed clearing heat and detoxicating, the carbuncle that disappears and to be fallen apart principle swollen, promoting blood circulation and removing blood stasis, provide a kind of feed being used for the treatment of mastadenitis of cow, it comprises Chinese medicine additive, and Chinese medicine additive comprises following raw medicinal material: Ageratum conyzoides, trichosanthes seed, cordate houttuynia, hawksbill turtle, Dysosma versipellis, Ku Zhi, fin Ji, fern beanstalk, lyrate hemistepta herb, selfheal, caulis trachelospermi ,sri Lanka Pouzolzia Herb, amplexicaul swallowwort herb, honeysuckle, the capsule of weeping forsythia, spina gleditsiae, dandelion, silene aprica, Ficus lyrata, clematis armandi Francs, the seed of cowherb, Radix Rhapontici seu Radix Echinopsis, play both sides of the street, pangolin, the Radix Astragali, Radix Angelicae Sinensis, Radix Glycyrrhizae.Ageratum conyzoides in its side, trichosanthes seed, cordate houttuynia, hawksbill turtle can disappear carbuncle sore; Dysosma versipellis, Ku Zhi, fin Ji ,fern beanstalk, lyrate hemistepta herb, selfheal, caulis trachelospermi are clearing heat and detoxicating, mass dissipating and swelling eliminating; Sri Lanka Pouzolzia Herb, amplexicaul swallowwort herb, honeysuckle, the capsule of weeping forsythia, spina gleditsiae, dandelion removing toxicity for detumescence, detoxification apocenosis; Silene aprica, Ficus lyrata, clematis armandi Francs, the seed of cowherb, Radix Rhapontici seu Radix Echinopsis, play both sides of the street, pangolin, dredging collateral for promoting lactation, activating blood circulation and dissipating blood stasis, controls alactation, acute mastitis, treatment pyogenic infections from tumour or sore; The Radix Astragali, Radix Angelicae Sinensis benefiting qi and nourishing blood, hold up spleen stomach invigorating, apocenosis pain relieving, green blood of invigorating blood circulation, the cloudy subcutaneous ulcer of Neto; In the sweet mitigation of Radix Glycyrrhizae, coordinating the drug actions of a prescription, all medicines share, loose swollen, the promoting blood circulation and removing blood stasis merit of clearing heat and detoxicating, the carbuncle that disappears of gathering altogether; Make a general survey of full side, compatibility is rigorous.
The pharmacological property of above-mentioned each raw medicinal material is as follows:
Ageratum conyzoides: be the herb of feverfew Ageratum conyzoides.Arduous, flat.Return lung, pericardium two warp.Expelling wind and clearing away heat, pain relieving, hemostasis, row's stone.For the infection of the upper respiratory tract, tonsillitis, sphagitis, acute gastroenteritis, stomachache, stomachache, uterine bleeding, kidney stone, vesical calculus; Eczema is controlled in external application, thrush, carbuncle pyogenic infections from tumour or sore, cellulitis, the ulcer of lower limb, tympanitis, traumatism and bleeding.
Trichosanthes seed: nature and flavor sweetness and bitterness, cold.Enter lung, stomach, large intestine channel.Compendium of Material Medica is said: " moistening lung is dry, falls fire.Control cough, wash phlegm knot, throat, subduing inflammation sore." " book on Chinese herbal medicine is just read " record: " and Snakegourd Fruit, nature and flavor are identical with pollen, only the profit merits and demerits of falling it.Therefore all stagnation of heat in upper-JIAO, the cards such as dirty greasy phlegm-fire cough, all can use it.The fiery person of genus of all lung carbuncle, acute appendicitis, acute mastitis, particularly suitable." function cures mainly: moistening lung, reduce phlegm, dissipating bind, ease constipation.Control phlegm-heat cough, the obstruction of qi in the chest, accumulation of pathogens in chest, consumptive lung disease hemoptysis, quenches one's thirst, jaundice, constipation, carbuncle swollen from the beginning of.
Cordate houttuynia: pungent, is slightly cold.Return lung channel.Clearing heat and detoxicating, the carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia.For lung carbuncle pyemesis, phlegm heat panting is coughed, hot dysentery, and heat is drenched, carbuncle sore tumefacting virus.
Hawksbill turtle: Gan Xian, cold.To start with few the moon, meridian of Foot-JUE YIN.Heat-clearing, removing toxic substances, relieving convulsion.Controlling pyreticosis shies mad, apoplexy, delirious speech, and convulsion is fainted, carbuncle sore tumefacting virus.
Dysosma versipellis: sweet, bitter is cool.Return lung, Liver Channel.Clearing heat and detoxicating, promoting blood circulation and removing blood stasis.Cure mainly venomous snake bite, traumatic injury; Worm snake bite is controlled in external application, carbuncle sore furuncle, lymphnoditis, mumps, breast cancer.
Ku Zhi: Solanaceae monkey flower Ku Zhi, with fruit, root or all herbal medicine.Hardship, cold.Clearing heat and detoxicating, swelling diuretic.For abscess of throat, mumps, acute and chronic tracheitis, lung abscess, dysentery, orchitis, difficult urination; Impetigo is controlled in external application.
Fin Ji: composite family fin Ji, is used as medicine with aerial part and root.Bitter; Cool in nature.Clearing heat and detoxicating; Vanishing sputum and dispelling knot; Cooling blood and hemostasis.Main sore and toxic; Scrofula; Hemoptysis; Bleeding from five sense organs or subcutaneous tissue; Spit blood; Have blood in stool.
Fern beanstalk: bitter, puckery, cool.Clearing heat and detoxicating, dispersing swelling and dissipating binds.For lung abscess, eye conjunctivitis; Traumatic injury is controlled in external application, snake bite, lymphoid tuberculosis.
Lyrate hemistepta herb: pungent is flat.Dispersing swelling and dissipating binds is clearing heat and detoxicating.For mastitis, cervical lymphadenitis, carbuncle swells furunculosis, rubella itch.
Selfheal: bitter, pungent, cold in nature, enters liver, gallbladder channel, " herbal classic ": " loose goitre knot gas, pin swells arthritis with fixed pain caused by dampness for main fever and chills, scrofula, mouse fistula, head sore, broken disease." " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " liver wind of dispelling, network of passing through, controls facial paralysis.Row irritability, opens liver depression, only arthralgia and myalgia, ophthal malgia, and loose scrofula is stolen, whole body tuberculosis." have and relieve inflammation or internal heat, improving eyesight, dissipating bind, effect of detumescence, cures mainly red eye, swell pain, and order pearl nyctalgia, has a headache dizzy, scrofula, and goiter and tumor, swells and ache; Thyroid Gland Swell, scrofula, the proliferation of mammary gland, the cards such as hypertension, hyperglycaemia, high fat of blood and high blood are sticky, selfheal all has inhibitory action to shigella dysenteriae, Escherichia coli, cholera bacilli etc.The function of selfheal is clear liver and improved vision, and uses stagnation resolvation knurl, also has the effect of diuretic antihypertensive.Among the peoplely to make tea with it again, do refrigerant passive heat agent.
Caulis trachelospermi: bitter, is slightly cold.The thoughts of returning home, liver, kidney channel." herbal classic ": " the dead flesh carbuncle wound of main air heat, dry tongue is burnt, and carbuncle is swollen not to disappear, and mouthpiece swells, water slurry not under." Tang Materia Medica: " treat blood knot in postpartum.Pallas pit viper sore, strand is got juice and is washed it, takes juice and also goes the snake venom heart vexed; The all sores of injury by sword or axe, Feng Zhi." have and dispel rheumatism, remove obstruction in channels to relieve pain, clearing heat and cooling blood, effect of removing toxicity for detumescence, cures mainly dispelling wind and removing obstruction in the meridians, cool blood detumescence.For beriberoid pyretic arthralgia, the contraction of muscle arteries and veins, soreness of waist and knee joint, larynx numbness, carbuncle swells, injury from falling down.The dull and stereotyped trench method of this product 50% decoction, has inhibitory action to staphylococcus aureus, shigella flexneri and typhoid bacillus.
Sri Lanka Pouzolzia Herb: sweet is cool.Clearing heat and promoting diuresis, detoxify and drain pus.For dysentery, enteritis, urinary tract infections; Furuncle is controlled in external application, mastitis.
Amplexicaul swallowwort herb: micro-hardship is flat.Return lung, the spleen channel.Clearing heat and detoxicating; Wines used as antirheumatic; Activating blood circulation and reducing swelling.Main air pain of dampness syndrome; Antimigraine; Pain in the back; Irregular menstruation; Acute mastitis; Carbuncle swells serious case of furuncle.
Honeysuckle: have another name called FLOSLONICERAE.Cold in nature, taste is sweet, enters lung, the heart, stomach warp, has effect that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treat wind, cures mainly disease under turgor, warm disease heating, the diseases such as hot malicious large carbuncle and tumour.The illnesss such as it is dizzy for giddy, dry is done yearningly, hidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, appendicitis, skin infection, ulcer furunculosis, erysipelas, mumps, suppurative tonsillitis all have certain curative effect.
The capsule of weeping forsythia: bitter, cold nature; Enter the heart, lung, small intestinl channel." property of medicine opinion ": " main tonneau five drenches, urinary obstruction, except heart man visitor heat." Tang Materia Medica: " capsule of weeping forsythia has two kinds, sticks up greatly, littlely to stick up.Stick up greatly leaf long and narrow, as wood, brightly yellowish lovely, give birth to wetland, work, like the Chinese toon person of not opening in fact, sticks up outstanding grass as room.On its little Qiao Sheng hilllock is former, Ye Huashi is all carefully little like sticking up greatly, and mountain people from south also uses it.Only with sticking up son greatly under modern capital, without stem flower also." pharmacological action such as have antibacterial, cardiac stimulant, diuresis, town to tell, be clearing heat and detoxicating Chinese medicine, cure mainly pyreticosis from the beginning of, anemopyretic cold, heating, vexed, symptom, its bacteriostasis and the honeysuckle broadly similar such as abscess of throat, acute nephritis, carbuncle sore tumefacting virus.Weakness of the spleen and the stomach, fever due to deficiency of vital energy, ulcer is burst, the light person of the rare look of purulence avoids clothes.
Spina gleditsiae: pungent, temperature; Enter lung, Liver Channel.Compendium of Material Medica: " Fructus Gleditsia acupuncture controls wind desinsection, and merit and pod are with, the different ear but its sharp keen through disease is done." containing glycosides displayed, phenols, amino acid.Flavone compound is young fustic, fisetin, and containing leucocyanidin.Chinese honey locust, for attacking loose high strict product, is not broken without heavily fortified point, does not fall apart without phlegm, can lead stagnant by switch, close disease with it, can help meet an urgent need to phlegm.Outer ulcer head is outstanding, and will burst when not bursting, utilize Chinese honey locust to break through its head, to cut for cutter, defeated and dispersed power is quite strong.
Dandelion: nature and flavor are sweet, micro-hardship, cold.Enter spleen, stomach, kidney three warp." Bencao Jingshu ": " dandelion is hidden sweet flat, and its property is nontoxic.When being enter stomach into liver, the key medicine of antipyretic cool blood." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " apply all pyogenic infections from tumour or sore, the ruined tinea sore of scabies; Dispel the wind, disappear all sores, loose scrofula tuberculosis; Stop little having blood in stool, control the five pouring retention of urines, sharp bladder." clearing heat and detoxicating, the carbuncle that disappears dissipating bind.Can be used for the infection of the upper respiratory tract, eye conjunctivitis, mumps, hyperglycaemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, cholecystitis, acute appendicitis, urinary infection, pelvic infecton, carbuncle furuncle furunculosis, pharyngitis, controls acute mastitis, adenolymphitis, scrofula, malignant boil carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infections.Containing multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, synanthrin in dandelion plant, there are the effects such as diuresis, laxative, removing jaundice subcutaneous ulcer, cholagogic.
Silene aprica: bitter, sweet, flat.Invigorating the spleen, diuresis, logical breast.Few for milk, body is impractical swollen.Invigorating the spleen, diuresis, logical breast.Few for milk, body is impractical swollen.
Ficus lyrata: sweet, temperature.The promoting flow of qi and blood circulation, stimulates the circulation of the blood and cause the muscles and joints to relax.For irregular menstruation, alactation, traumatic injury, pain in the back pain; Mastitis is controlled in external application.
Clematis armandi Francs: pungent; Bitter; Warm in nature.Return liver, urinary bladder channel.Expelling wind and activating blood flow; Inducing diuresis for treating strangurtia.Main joint swells and ache; Traumatic injury; Difficult urination; Alactation.
Play both sides of the street: bitter, flat; Return liver, kidney channel." detailed outline is picked up any lost article from the road ": " maple fruit, tree is like white poplar, and inner circle, as honeycomb, namely plays both sides of the street.The large acupoints of twelve meridians that can pass through of its property, therefore " the lifesaving sea of bitterness " harnesses the river, swelling is with it, can search by Fu Shuiye with it." " modern Practical Chinese medicinal ": " ashing is outer for skin exudative dermatitis, anal fistula etc., has convergence, anti-inflammatory, disinfective action." dispelling, collateral-activating, Li Shui stimulates the menstrual flow.For joint pain, numbness contracture, oedema turgor, breast is few through closing.Play both sides of the street the property of tool tonneau, pain relieving during function promoting the circulation of qi is wide, clinically for abdominal distention, the disease such as not well of defecating, can be equal to use with the banksia rose, the root of three-nerved spicebush, Fructus Aurantii.This product has again effect of inducing diuresis for removing edema, for oedema, can with the compatibilities such as fuling peel, the root bark of white mulberry, waxgourd peel.
The seed of cowherb: bitter is flat; Return liver, stomach warp." book on Chinese herbal medicine newly organized ": " seed of cowherb, its property is very anxious, descending and do not go up passerby also.Inverse and the upper punch person of all diseases with can fall, therefore can rely on to make it use as minister also.But its property is overrun, should be for a long time unsuitable temporarily, can not know again yet.Or ask: the seed of cowherb can lactogenesis, be also can be up thing also.Not knowing breast not descend and descend it, is descending after all, but not also up.Upper Jiao has can descend person, all can descend logical, non-only row in the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels not all right in the part of the body cavity above the diaphragm housing the heart and lungs also." can promoting circulation of blood menstruation regulating, swelling and pain relieving, logical breast of invigorating blood circulation, expedite the emergence of lactogenesis, thymus gland dredging in postpartum.For blood stasis through closing, dysmenorrhoea, difficult labour; Lack of lactation after delivery, acute mastitis swells and ache; Heat is drenched, and blood drenches, urolithiasis.
Radix Rhapontici seu Radix Echinopsis: bitter is salty, cold; Enter stomach, large intestine channel.Shennong's Herbal: " Radix Rhapontici seu Radix Echinopsis bitter is salty-cold.Main skin heat, evil wound, subcutaneous ulcer hemorrhoid, lower milk ... one wild blue.Raw mountain valley." " Bencao Jingshu ": " and Radix Rhapontici seu Radix Echinopsis, hardship can be let out down, the soft heavily fortified point of salty energy, cold can heat extraction, the cold and medicine of tonneau is also.Therefore main skin heat, dislike sore subcutaneous ulcer hemorrhoid, arthritis with fixed pain caused by dampness, lower milk." clearing heat and detoxicating, apocenosis is subsided a swelling, and disappear carbuncle, lactogenesis, and relaxing muscles and tendons is promoted blood circulation.Swell and ache for acute mastitis, ulcer carbuncle on the back, scrofula sore, alactation, arthritis with fixed pain caused by dampness contraction, arthralgia, toxic-heat and blood stasis, hemorrhoid hemorrhage.Radix Rhapontici seu Radix Echinopsis water logging agent (1:3), is had inhibitory action in various degree to permitting the dermatophyte such as blue achorion, star-shaped nocardia in vitro.Radix Rhapontici seu Radix Echinopsis can be used for again various tumour clinically.
Pangolin: taste is salty, cold nature; Return liver, stomach warp." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " control scabies leprosy carbuncle poison, relieving stagnant Qi promoting circulation of blood, chest diaphragm expands against gas, controls bladder hernia pain." Compendium of Material Medica: " eliminating phlegm malaria fever and chills, the tetanic pain of wandering arthritis, qualcomm meridian, lower milk, subduing inflammation, apocenosis blood, sensible desinsection." blood circulation promoting and dispersing pathogen accumulation, lactogenesis of stimulating the menstrual flow, the carbuncle that disappears is burst hard.Main blood stasis is through closing, and abdominal mass, arthralgia due to wind-dampness, agalactia, carbuncle swells, scrofula.Pangolin has preferably logical lower milk effect, and for alactation in postpartum, can single be end, yellow rice wine takes.For strengthening lactogenesis effect, many and seed of cowherb compatibility; If postpartum is qi-blood deficiency, milk is rare, the same use of the medicine such as yellow over sixty years of age, Radix Angelicae Sinensis of blood-enrich can be closed.
Radix Glycyrrhizae: nature and flavor are sweet, flat.Enter spleen, stomach, lung channel." herbal classic " is said: " main the five internal organs six mansion fever and chills perverse trend, hard muscles and bones, longue meat, times power, metal-inflicted wound swells, removing toxic substances "." property of medicine opinion " is said: " crymodynia in main abdomen, controls frightened epilepsy, except distention and fullness in the abdomen; Help the five internal organs; Make all medicines poison; Support kidney qi internal injury, make impotence; Housewife's human blood drop pain in the back; Empty and how heat; Add and with it ".Can beneficial gas bowl spares, relieving spasm to stop pain, moistens the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription.Main burnout food is few, flesh thin Huang, palpitation, stomachache loose stool, and the anxious pain of four limbs contraction, hysteria, cough and asthma, abscess of throat, carbuncle sore swells and ache, and medicine, food poisoning.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, the anxious pain of gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Western modern medicine haircut is existing, and Radix Glycyrrhizae agent has the function of anti-inflammatory and the reflection of resistance state, therefore in doctor trained in Western medicine clinically mainly as moderator.Relieving cough, eliminates the phlegm, treatment pharyngalgia laryngitis; Radix Glycyrrhizae or enoxolone have the effect of desoxycortone class, have good effects to chronic adrenocortical hypofunction; Glycyrrhiza preparation can promote stomach mucus to be formed and secretion, extends the epithelial cell life-span, has anti-inflammatory activity, be usually used in the treatment of chronic ulcer and duodenal ulcer; The flavones of Radix Glycyrrhizae has anti-inflammatory, spasmolysis and antiacid effect; Radix Glycyrrhizae is also one of primary raw material of jintan.
Radix Angelicae Sinensis: taste is sweet, pungent, bitter, warm in nature, enters liver, the heart, the spleen channel, " Treatise on Febrile Disease with Notes ": " the arteries and veins person house of blood, all blood all belongs to the heart, and all persons of promoting blood circulation must first bushing benefit blood, therefore Zhang Zhongjing is controlled brothers and fainted cold, thready pulse being about to disappear person, by the hardship temperature of Radix Angelicae Sinensis to help painstaking effort." " book on Chinese herbal medicine is newly organized ": " Radix Angelicae Sinensis, taste is sweet pungent, temperature, can rise and can fall, the YIN aspect of YANG, nontoxic.Though there be upper and lower point, enrich blood then one.Enter the heart, spleen, liver three are dirty.But its property is very dynamic, then tonifying Qi in the Qi-tonifying drug entered, then enriches blood in the antianaemics entered, without determining merit also." have to enrich blood and invigorate blood circulation, the effect of menstruction regulating and pain relieving, profit soup defaecation, sallow for the deficiency of blood, dizzy palpitaition, irregular menstruation, through closing the cards such as dysmenorrhoea, asthenia cold abdominalgia, the dry constipation of intestines, arthralgia due to wind-dampness, injury from falling down, ulcer sores.
The Radix Astragali: sweet, tepor; Return lung, spleen, liver, kidney channel.Essentials of Matea Medica: " Radix Astragali, raw with solid table, losslessly to send out, to have sweat to stop; Process with bowl spares, beneficial vigour, strong taste.Green blood, myogenic, apocenosis Neto, sore carbuncle panacea.Variola does not rise, and the deficiency of yang should it without hot person." " book on Chinese herbal medicine justice ": " temperature supports taste, and all middle gas is depressed for the Radix Astragali, soil in help, and spleen soil is weak, and the clear gas person of sinking is the most suitable.Its skin goes directly the skin table muscle of people, and solid protection defends sun, and enriching table point, is its speciality, so all diseases of exterior deficiency, and the most refreshing agent." function shows arrest sweating, inducing diuresis for removing edema admittedly, the apocenosis of holder sore, regulating fluid apssage.The Radix Astragali makes contractile ability strengthen, and can improve the blood circulation of whole body, can coronary artery dilator, Renal vascular and adder-wort peripheral vessel, make skin blood overactive circulation; The nonspecific immunity power of body can be improved, protect the liver and fall hypoglycemic effect, have inhibitory action to staphylococcus, blood dissolubility streptococcus, Diplococcus pneumopniae, shigella dysenteriae etc.The Radix Astragali can significantly affect SPL Information Conduction, realizes immunoregulation effect.Can be used for high blood pressure, ischemic heart disease, acute glomerulonephritis, gastric ulcer, psoriasis, diabetes, osteoporosis.
Caulis Perillae: pungent, temperature.Return lung, the spleen channel.Regulate the flow of vital energy, Shu Yu, pain relieving, antiabortive.Control the obstruction of the circulation of vital energy, eat stagnant, chest diaphragm ruffian is vexed, epigastric pain, and nausea is got along well.
Finger citron flower: be flower and the bud of rutaceae Buddha's hand.Micro-hardship; Tepor.Return liver; Stomach warp.Dispersing stagnated hepatoqi; With stomach soon every.Main stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.
Buckeye: sweet, temperature.Return liver, stomach warp.Soothing the liver; Regulate the flow of vital energy; In wide; Pain relieving.The main chest side of body; Swollen breasts; Dysmenorrhoea; Epigastric pain.
Rascal: nature and flavor toil, temperature.Enter liver, courage, stomach warp.Can soothing the liver relieving stagnant Qi, long-pendingization that disappear stagnant.For sternal rib gastral cavity distending pain, acute mastitis, colic, stagnation of QI due to dyspepsia.Modern pharmacology experimental study shows: rascal parenteral solution can reduce the tonic contraction of isolated guinea pig stomach, intestines, gall-bladder and Mouse Uterus, and makes smooth muscle of bladder excited.The gallbladder contraction that the guinea pig in vitro stomach caused acetylcholine, intestines and rabbit cause at body pipe smooth muscle and carbaminoylcholine, has significant spasmolysis.The rabbit that the guinea pig in vitro intestines cause histamine and physostigmine salicylate cause, in body intestines tonic contraction, has significant inhibitory action.The Mouse Uterus tonic contraction that pituitrin causes can be resisted.To the hormesis of cavy at body bladder and Rabbit thoracic aorta, mainly through excited adrenergic α receptor, and more weak than norepinephrine to aortal excitation.The energy perfusion flow that significantly Eff ect in Guinea Pigs lung causes because of histamine reduces, and can remove the spasm effect of histamine to bronchus chain.Also significantly can increase the bile flow of rat, and biliary tract tension force is increased.
Fructus Aurantii: relieving stagnant Qi, row phlegm, disappears long-pending.Control chest diaphragm phlegm stagnant, the feeling of stuffiness in chest, coerce swollen, dyspepsia, gas, vomit inverse, heavy after diarrhea, prolapse of the anus, the prolapse of uterus.1. " property of medicine opinion ": control rubella all over, dislike and itch, main intestines wind haemorrhoids, stagnation of vital energy in the chest and abdomen in flesh as numb beans, the swollen void of two sides of body, pass diaphragm is congested.2. " Japan hanako materia medica ": spleen benefiting and stimulating the appetite, adjust the five internal organs, lower gas, preventing or arresting vomiting is inverse, dissolving phlegm.Control gastric disorder causing nausea, cholera rushes down dysentery, helps digestion, and broken crux Xuan addiction, five types of dysphagia, except wind improving eyesight and lung qi oedema, sharp intestine and small intestine, skin is itched.Swollen can the processing of hemorrhoid is pressed.3. " Kaibao Bencao ": main air is itched paralysis, easing joint movement, labor gas is coughed, and back of the body arm is bored and listless, loosely stays knot, chest diaphragm phlegm stagnant, relieves oedema or abdominal distension through diuresis or purgation, dissipate-swelling is full, large intestine wind, and peace stomach, only wind bitterly.4. " pearl sac ": relieving stagnant Qi, gas unfavorable in lung is let out.5. " medicine origin ": " curing mainly secret formula " cloud, broken hardness in the epigastrium ruffian, profit is gas in the heart, reduces phlegm, and 6. help digestion " detailed outline ": control tenesmus.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine additive
Get Ageratum conyzoides 15 weight portion, trichosanthes seed 22 weight portion, cordate houttuynia 17 weight portion, hawksbill turtle 12 weight portion, Dysosma versipellis 6 weight portion, bitter Zhi 15 weight portion, fin Ji 13 weight portion, fern beanstalk 14 weight portion, lyrate hemistepta herb 26 weight portion, selfheal 13 weight portion, caulis trachelospermi 15 weight portion ,sri Lanka Pouzolzia Herb 20 weight portion, amplexicaul swallowwort herb 18 weight portion, honeysuckle 16 weight portion, the capsule of weeping forsythia 14 weight portion, spina gleditsiae 10 weight portion, dandelion 23 weight portion, silene aprica 12 weight portion, Ficus lyrata 17 weight portion, clematis armandi Francs 15 weight portion, the seed of cowherb 16 weight portion, Radix Rhapontici seu Radix Echinopsis 17 weight portion, 23 weight portions that play both sides of the street, pangolin 15 weight portion, the Radix Astragali 16 weight portion, Radix Angelicae Sinensis 21 weight portion and Radix Glycyrrhizae 22 weight portion.
Preparation method comprises the following steps:
The first step, mixes in proportion by described each raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 times is the ethanol of 85%, adds hot reflux 1 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 times to be again the ethanol of 85%, to add hot reflux 2 hours that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 hour, pulverize, sieve, obtain 300 object micropowders, obtain Chinese medicine additive powder.
Embodiment 2 feed
Embodiments provide a kind of feed being used for the treatment of mastadenitis of cow, in feed, the parts by weight of each raw material are: corn flour 40 weight portion, oyster shell whiting 15 weight portion, cottonseed cake 25 weight portion, wheat bran 35 weight portion, bone meal 12 weight portion, soya-bean cake 23 weight portion, pumpkin 19 weight portion, loquat 11 weight portion, lotus rhizome 16 weight portion, carrot 27 weight portion, dark plum 13 weight portion, banana 16 weight portion, sea-tangle 12 weight portion, vitamin premix 0.4 weight portion, microelement pre-mix material 0.3 weight portion and Chinese medicine additive 4 weight portion; Wherein Chinese medicine additive is the Chinese medicine additive powder of embodiment 1.
Its preparation method comprises the following steps:
(1) destruction step: take cottonseed cake, soya-bean cake, pumpkin, loquat, lotus rhizome, carrot, dark plum, banana, sea-tangle by ratio of weight and the number of copies, drops into pulverizer and carries out Crushing of Ultrafine, crosses 1.0mm sieve after pulverizing;
(2) batching step: take corn flour, oyster shell whiting, wheat bran, bone meal, vitamin premix, microelement pre-mix material and Chinese medicine additive according to ratio of weight and number, pulverize with step (1) fine powder obtained to mix, drop into mixer, mix, incorporation time is 40s;
(3) granulation step: drop into granulator and granulate, pelleting temperature is 85 DEG C, makes its gelatinization degree reach more than 90%.
The toxicity test of Chinese medicine additive:
1, trial drug
Choose Ageratum conyzoides 15g, trichosanthes seed 22g, cordate houttuynia 17g, hawksbill turtle 12g, Dysosma versipellis 6g, Ku Zhi 15g, fin Ji 13g, fern beanstalk 14g, lyrate hemistepta herb 26g, selfheal 13g, caulis trachelospermi 15g ,sri Lanka Pouzolzia Herb 20g, amplexicaul swallowwort herb 18g, honeysuckle 16g, capsule of weeping forsythia 14g, spina gleditsiae 10g, dandelion 23g, silene aprica 12g, Ficus lyrata 17g, clematis armandi Francs 15g, seed of cowherb 16g, Radix Rhapontici seu Radix Echinopsis 17g, the 23g that plays both sides of the street, pangolin 15g, Radix Astragali 16g, Radix Angelicae Sinensis 21g and Radix Glycyrrhizae 22g mix, and are ground into powder; Added by acquisition powder in 1400g cold water and soak 25 hours, with slow fire boiling, decocting time is 1.5 hours, decoction liquor is filtered, obtains the first filtrate, collects filter residue; Again add in 1400g cold water by filtering the filter residue obtained, with slow fire boiling 3 times, each decoction 1 hour, filters and merges filtered fluid, obtaining the second filtrate; Merge twice filtrate, reduced pressure concentration remove portion water, obtain decoction, the crude drug concentration of decoction is 3g/ml.
2, test method: select SD rat, the Chinese medicine additive of the present invention giving variable concentrations (18.0,6.0,2.0g crude drug/kg) is boiled into decoction, every day gavage once, continuous 90 days, within after last administration 24 hours, respectively group is alive kills 1/2 animal (male and female half and half), and all the other 1/2 animals continue observations 2 weeks rear living and kill.Duration of test observes outward appearance, general behavior, food ration, the changes of weight of animal, within after administration 90 days, within 2 weeks, carries out the index checking such as hematology (RBC, HB, granulophilocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, Histopathology with drug withdrawal.Result of the test shows: Chinese medicine additive of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and control group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range (NR), without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, rat is had no significant effect in high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) administration in continuous 90 days according to result of the test Chinese medicine preparation of the present invention, without clear and definite toxicity target organ and sensitive indicator, convalescence observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention higher.
Contrast test
Veterinary station of Zhangqiu in Shandong province, in October ,-2014 in February, 2013, see and treat patients 65 and suffer from the milk cow of mastitis, suffer from poultry cow breast and locally occur swollen hard, erythrosis, heating pain, when standing, hind leg is opened a business, and is slow in action, time sleeping, forelimb is gone down on one's knees, hind leg dare not land, and indivedual milk cow also has appetite to ruminate minimizing, One's spirits are drooping symptom.
Choose 20 ill milk cows and be divided into two groups at random, be respectively embodiment group and control group, the ill milk cow of two groups all without significant difference, has comparativity in body weight, the state of an illness etc.Embodiment group and control group use the feed of the embodiment of the present invention 2 and conventional feed to feed ill milk cow respectively, feed continuously 7 days, and wherein, control group also needs to carry out conventional therapy and intramuscular injection penicillin 1,500,000 unit and streptomysin 1,600,000 unit, once a day.Experimental period is 7 days, and result is as shown in table 1.
Efficacy determination: recovery from illness, clinical symptom disappearance, milk recovers normal, and LMT detects somatic number (SCC) in milk and is less than 500,000/mL.Effectively, clinical symptom disappearance, milk recovers normal, and LMT detects SCC between 500,000 ~ 1,000,000/mL.Invalid, clinical symptoms do not disappear and even increase the weight of, and milk still has ANOMALOUS VARIATIONS, and LMT detects SCC and is greater than 1,000,000/mL.
The result for the treatment of table of comparisons of table 1 liang experimental group ox
Group Sum Recovery from illness number Significant figure Invalid number Total effective rate
Embodiment group 10 10 0 0 100%
Control group 10 7 1 2 80.0%
Data from table 1: compared with conventional medicament, the feed of the embodiment of the present invention 2 has advantage that is evident in efficacy, cheap, that have no side effect in treatment mastadenitis of cow.
Model case
Distributions in Liaocheng of Shandong Province one peasant household ox cow breast of seeing and treating patients in September, 2013 locally occurs swollen hard, erythrosis, and when standing, hind leg is opened a business, and is slow in action, One's spirits are drooping symptom.Be diagnosed as mastitis.Immediately by the powder of the embodiment of the present invention 1, be mixed in conventional feed feed continuously 7 days according to the part by weight of 4:100, after 3 days, symptom starts to take a turn for the better, and is used in conjunction recovery from illness in 7 days.After half a year, follow up a case by regular visits to that all are normal.
There is listlessness, enlargement on the left of breast in the ox of Weifang, Shandong in November, 2013 farm breeds, heating, and pain refuses to touch, and when standing, hind leg is opened a business, and is slow in action, and time sleeping, forelimb is gone down on one's knees, and hind leg dare not land.Be diagnosed as mastitis.The feed of the embodiment of the present invention of feeding immediately 2, after 2 days, symptom alleviates, and appetite increases, and spirit takes a turn for the better, recovery from illness in the 5th day.All are followed up a case by regular visits to normal after half a year.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (9)

1. a milk cow mixed feed, it is characterized in that, described feed comprises following raw material: corn flour, oyster shell whiting, cottonseed cake, wheat bran, bone meal, soya-bean cake, pumpkin, loquat, lotus rhizome, carrot, dark plum, banana, sea-tangle, vitamin premix and microelement pre-mix material.
2. milk cow mixed feed according to claim 1, it is characterized in that, in described feed, the parts by weight of each raw material are: corn flour 30-50 weight portion, oyster shell whiting 10-20 weight portion, cottonseed cake 20-30 weight portion, wheat bran 30-40 weight portion, bone meal 10-15 weight portion, soya-bean cake 20-25 weight portion, pumpkin 15-25 weight portion, loquat 10-15 weight portion, lotus rhizome 10-20 weight portion, carrot 20-30 weight portion, dark plum 10-15 weight portion, banana 10-20 weight portion, sea-tangle 10-25 weight portion, vitamin premix 0.1-0.5 weight portion and microelement pre-mix material 0.1-0.5 weight portion.
3. milk cow mixed feed according to claim 1 and 2, it is characterized in that, described feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: corn flour 30-50 weight portion, oyster shell whiting 10-20 weight portion, cottonseed cake 20-30 weight portion, wheat bran 30-40 weight portion, bone meal 10-15 weight portion, soya-bean cake 20-25 weight portion, pumpkin 15-25 weight portion, loquat 10-15 weight portion, lotus rhizome 10-20 weight portion, carrot 20-30 weight portion, dark plum 10-15 weight portion, banana 10-20 weight portion, sea-tangle 10-25 weight portion, vitamin premix 0.1-0.5 weight portion, microelement pre-mix material 0.1-0.5 weight portion and Chinese medicine additive 2-5 weight portion.
4. the milk cow mixed feed according to any one of claim 1-3, it is characterized in that, in described feed, the parts by weight of each raw material are: corn flour 40 weight portion, oyster shell whiting 15 weight portion, cottonseed cake 25 weight portion, wheat bran 35 weight portion, bone meal 12 weight portion, soya-bean cake 23 weight portion, pumpkin 19 weight portion, loquat 11 weight portion, lotus rhizome 16 weight portion, carrot 27 weight portion, dark plum 13 weight portion, banana 16 weight portion, sea-tangle 12 weight portion, vitamin premix 0.4 weight portion, microelement pre-mix material 0.3 weight portion and Chinese medicine additive 4 weight portion.
5. the milk cow mixed feed according to any one of claim 1-4, it is characterized in that, described Chinese medicine additive comprises following raw medicinal material: Ageratum conyzoides, trichosanthes seed, cordate houttuynia, hawksbill turtle, Dysosma versipellis, Ku Zhi, fin Ji, fern beanstalk, lyrate hemistepta herb, selfheal, caulis trachelospermi ,sri Lanka Pouzolzia Herb, amplexicaul swallowwort herb, honeysuckle, the capsule of weeping forsythia, spina gleditsiae, dandelion, silene aprica, Ficus lyrata, clematis armandi Francs, the seed of cowherb, Radix Rhapontici seu Radix Echinopsis, play both sides of the street, pangolin, the Radix Astragali, Radix Angelicae Sinensis and Radix Glycyrrhizae.
6. the milk cow mixed feed according to any one of claim 1-5, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: Ageratum conyzoides 10-18 weight portion, trichosanthes seed 20-28 weight portion, cordate houttuynia 15-23 weight portion, hawksbill turtle 10-18 weight portion, Dysosma versipellis 5-8 weight portion, Ku Zhi 10-16 weight portion, fin Ji 12-17 weight portion, fern beanstalk 11-19 weight portion, lyrate hemistepta herb 20-29 weight portion, selfheal 8-14 weight portion, caulis trachelospermi 13-18 weight portion ,sri Lanka Pouzolzia Herb 12-22 weight portion, amplexicaul swallowwort herb 16-28 weight portion, honeysuckle 15-19 weight portion, capsule of weeping forsythia 10-17 weight portion, spina gleditsiae 8-16 weight portion, dandelion 22-28 weight portion, silene aprica 11-17 weight portion, Ficus lyrata 16-25 weight portion, clematis armandi Francs 12-18 weight portion, seed of cowherb 14-17 weight portion, Radix Rhapontici seu Radix Echinopsis 12-19 weight portion, the 15-25 weight portion that plays both sides of the street, pangolin 10-16 weight portion, Radix Astragali 10-18 weight portion, Radix Angelicae Sinensis 18-25 weight portion and Radix Glycyrrhizae 15-26 weight portion.
7. the milk cow mixed feed according to any one of claim 1-6, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: Ageratum conyzoides 15 weight portion, trichosanthes seed 22 weight portion, cordate houttuynia 17 weight portion, hawksbill turtle 12 weight portion, Dysosma versipellis 6 weight portion, Ku Zhi 15 weight portion, fin Ji 13 weight portion, fern beanstalk 14 weight portion, lyrate hemistepta herb 26 weight portion, selfheal 13 weight portion, caulis trachelospermi 15 weight portion ,sri Lanka Pouzolzia Herb 20 weight portion, amplexicaul swallowwort herb 18 weight portion, honeysuckle 16 weight portion, the capsule of weeping forsythia 14 weight portion, spina gleditsiae 10 weight portion, dandelion 23 weight portion, silene aprica 12 weight portion, Ficus lyrata 17 weight portion, clematis armandi Francs 15 weight portion, the seed of cowherb 16 weight portion, Radix Rhapontici seu Radix Echinopsis 17 weight portion, 23 weight portions that play both sides of the street, pangolin 15 weight portion, the Radix Astragali 16 weight portion, Radix Angelicae Sinensis 21 weight portion and Radix Glycyrrhizae 22 weight portion.
8. the milk cow mixed feed according to any one of claim 1-7, is characterized in that, the preparation method of described Chinese medicine additive comprises the following steps:
The first step, mixes in proportion by described each raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, adds hot reflux 1 ~ 3 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 ~ 2 times to be again the ethanol of 85 ~ 95%, to add hot reflux 1 ~ 3 hour that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders, obtain Chinese medicine additive powder.
9. the preparation method of the milk cow mixed feed according to any one of claim 1-8, is characterized in that, described preparation method comprises the following steps:
(1) destruction step: take cottonseed cake, soya-bean cake, pumpkin, loquat, lotus rhizome, carrot, dark plum, banana, sea-tangle by ratio of weight and the number of copies, drops into pulverizer and carries out Crushing of Ultrafine, crosses 1.0mm sieve after pulverizing;
(2) batching step: take corn flour, oyster shell whiting, wheat bran, bone meal, vitamin premix, microelement pre-mix material and Chinese medicine additive according to ratio of weight and number, pulverize with step (1) fine powder obtained to mix, drop into mixer, mix, incorporation time is 30-60s;
(3) granulation step: drop into granulator and granulate, pelleting temperature is 85 DEG C, makes its gelatinization degree reach more than 90%.
CN201510617410.5A 2015-09-25 2015-09-25 Milk cow compound feed and making method thereof Pending CN105166546A (en)

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