CN103877457A - Chinese medicinal preparation for treating renal calculus and preparation method thereof - Google Patents

Chinese medicinal preparation for treating renal calculus and preparation method thereof Download PDF

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CN103877457A
CN103877457A CN201410143500.0A CN201410143500A CN103877457A CN 103877457 A CN103877457 A CN 103877457A CN 201410143500 A CN201410143500 A CN 201410143500A CN 103877457 A CN103877457 A CN 103877457A
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马忠堂
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马忠堂
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Abstract

The invention discloses a Chinese medicinal preparation for treating renal calculus and a preparation method thereof, belonging to the field of traditional Chinese medicine. The active ingredients of the Chinese medicinal preparation are prepared from the following raw materials: polygonum aviculare, plantain seed, pink herb, chicken gizzard membrane, mirabilite, common burreed rhizome, cowherb seed, officinal magnolia bark, common cephalanoplos herb, Chinese honeylocust spine, rust-brown crotalaria, fragrant solomonseal rhizome, ricepaper pith, longhairy antenoron herb, Indian buead and pyrrosia leaf. The Chinese medicinal preparation has the effects of diminishing inflammation, relieving pain, promoting blood circulation to remove blood stasis, promoting the circulation of qi, removing stasis, inducing diuresis and expelling calculi, is suitable for renal calculus patients having the symptoms of waist aching pain, generalized weakness, unsmooth urination, hematuresis and the like, has remarkable curative effect, and is free of toxic and side effects, and low in cost. The Chinese medicinal preparation is strict in compatibility, has the effects of supplementing kidney qi, improving the gasifying function of urinary bladder, promoting normal urinary function, dissolving calculi and removing urinary calculi, is high in safety, and contributes to relieving pain of patients in time.

Description

A kind of Chinese medicine preparation and preparation method for the treatment of renal calculus
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation and preparation method for the treatment of renal calculus.
Background technology
Renal calculus is a kind of frequently-occurring disease, commonly encountered diseases; clinical take renal colic and hematuria as cardinal symptom; often can cause urinary tract obstruction; and secondary infection; according to the difference of stone composition; renal calculus can be divided calcium oxalate stone, calcium phosphate stone, urate calculus, struvite calculus, cystine stone and purine calculus six classes, clinical two types of excess syndrome and the syndrome of intermingled deficiency and excess that are often divided into:
1. case of a physically strong patient running a high fever type: burning into sand stone in urine time, urine is involved and abstruse, or interrupts suddenly while urinating, the poverty-stricken pain of urethra, cramp and pain in the lower abdomen, or waist angina abdominis is unbearably, is with blood in urine, red tongue, yellow and thin fur, stringy pulse or band number.
2. simulataneous insufficiency and excessive type: sick sandstone for a long time does not go, can accompany and see spiritlessness and weakness, down in spirits, and the few China of pallor, light red tongue has indentation, thready and weak pulse without strength, or accompany waist abdomen to have a dull ache, and soreness of the waist and knees, feverish sensation in the palms and soles, hectic fever, night sweat, spiritlessness and weakness, the few tongue of red tongue, pulse condition is counted accurately.
Renal calculus be mineral crystallization deposition in urine in kidney, move to sometimes ureter.
(1) clinical manifestation individual difference is very large, be decided by calculus the cause of disease, composition, size, number, position, mobility, have or not to block and infect and the degree of excess of the kidney matter pathological lesion.The lighter can not have symptom completely, serious occurred anuria, renal failure, toxic shock and death.
(2) when calculus incarceration declines in Ureteropelvic junction or ureter, can there is renal colic, for the paroxysmal cutting pains breaking out, sharp ache unbearably, patient is toss about and feel uneasy, pain is radiated to bladder area downwards from waist or flank portion, and external genital and femoribus internus have profuse sweating, nausea and vomiting sometimes.
(3) because calculus is heavier to mucosa injury, therefore often there is gross hematuria.Pain and the hematuria patient activity of being everlasting is brought out when more.When calculus accompanying infection, in urine, there is pus cell, have frequent micturition, dysurea symptom.
(4) in the time of secondary acute pyelonephritis or pyonephrosis, the General Symptoms such as can have heating, fear of cold, shiver.When lithangiuria or renal calculus are blocked completely on bilateral, can cause anuria.
At present, the medicine for the treatment of clinically renal calculus is more, but because the structure of kidney is special, the fossil lithodialysis function of the effect of Drug therapy and medicine is not satisfactory, and most patients are not able to and proceed to operative treatment; And operative treatment is often with side effect such as drug allergy, postoperative easy recurrence, economic spending is large, and wound is large, and treatment time is long, brings serious economy and body burden to sufferer.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of renal calculus, Chinese medicine preparation of the present invention has effect of anti-inflammatory analgetic, blood circulation promoting and blood stasis dispelling, promoting QI to circulate and dispersing the agglomeration of the pathogens, diuresis and expelling stone, be applicable to the renal calculus patient of the symptoms such as waist is ached, the whole body is weak, it is not smooth to urinate, hematuria, and evident in efficacy, have no side effect, with low cost; Chinese medicine preparation compatibility of the present invention is rigorous, has supplementary kidney qi, increases the gasification function of bladder, impels urinary function normal, produces lithodialysis, calculus removing effect, and safe, is conducive to patient's symptom that eases the pain in time.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for renal calculus, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
25~60 parts of 30~60 parts of Endothelium Corneum Gigeriae Galli of 30~65 portions of Herba Dianthis of 35~70 portions of Semen Plantaginiss of Herba Polygoni Avicularis
20~50 parts of 20~50 parts of Cortex Magnoliae Officinalis of 25~55 parts of Semen Vaccariae of 25~55 parts of Rhizoma Sparganii of Natrii Sulfas
15~40 parts of 15~40 portions of Rhizoma Polygonati Odorati of 20~45 parts of Herba Crotalariae Ferrugineaes of 20~45 parts of Spina Gleditsiaes of Herba Cirsii
5~35 parts of 10~35 parts of Folium Pyrrosiaes of 10~40 parts of Poria of 10~45 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
30~55 parts of 35~55 parts of Endothelium Corneum Gigeriae Galli of 35~60 portions of Herba Dianthis of 40~65 portions of Semen Plantaginiss of Herba Polygoni Avicularis
25~45 parts of 25~45 parts of Cortex Magnoliae Officinalis of 30~50 parts of Semen Vaccariae of 30~50 parts of Rhizoma Sparganii of Natrii Sulfas
20~35 parts of 20~35 portions of Rhizoma Polygonati Odorati of 25~40 parts of Herba Crotalariae Ferrugineaes of 25~40 parts of Spina Gleditsiaes of Herba Cirsii
10~30 parts of 15~30 parts of Folium Pyrrosiaes of 15~35 parts of Poria of 15~40 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
35~50 parts of 40~51 parts of Endothelium Corneum Gigeriae Galli of 40~56 portions of Herba Dianthis of 45~60 portions of Semen Plantaginiss of Herba Polygoni Avicularis
30~40 parts of 30~40 parts of Cortex Magnoliae Officinalis of 35~45 parts of Semen Vaccariae of 35~45 parts of Rhizoma Sparganii of Natrii Sulfas
25~30 parts of 25~30 portions of Rhizoma Polygonati Odorati of 30~35 parts of Herba Crotalariae Ferrugineaes of 30~35 parts of Spina Gleditsiaes of Herba Cirsii
15~25 parts of 20~25 parts of Folium Pyrrosiaes of 20~30 parts of Poria of 20~35 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
42 parts of 43 parts of Endothelium Corneum Gigeriae Galli of 48 portions of Herba Dianthis of 52 portions of Semen Plantaginiss of Herba Polygoni Avicularis
35 parts of 35 parts of Cortex Magnoliae Officinalis of 40 parts of Semen Vaccariae of 40 parts of Rhizoma Sparganii of Natrii Sulfas
28 parts of 28 portions of Rhizoma Polygonati Odorati of 32 parts of Herba Crotalariae Ferrugineaes of 33 parts of Spina Gleditsiaes of Herba Cirsii
20 parts of 23 parts of Folium Pyrrosiaes of 25 parts of Poria of 27 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
Treat a preparation method for the Chinese medicine preparation of renal calculus, comprise following processing step:
(1) Herba Polygoni Avicularis, Semen Plantaginis and Herba Cirsii are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(2) Herba Dianthi, Rhizoma Sparganii, Semen Vaccariae, Cortex Magnoliae Officinalis, Herba Crotalariae Ferrugineae, Rhizoma Polygonati Odorati, Medulla Tetrapanacis, Poria and Folium Pyrrosiae are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.16, for subsequent use;
(3) Endothelium Corneum Gigeriae Galli and Natrii Sulfas are mixed, after mix homogeneously, carry out pulverization process, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Spina Gleditsiae and Herba Lysimachiae are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filter, and the thick paste that at 70 ℃ of simmer down tos, relative density is 1.15~1.18, for subsequent use;
(5) above-mentioned steps (1)~(4) prepared juice, thick paste and fine powder are mixed, make tablet, obtain the Chinese medicine preparation for the treatment of renal calculus of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Polygoni Avicularis: bitter in the mouth, cold in nature; Enter spleen, kidney two warps.Diuresis, heat clearing away, parasite killing.Control pyretic stranguria, the difficulty in urination, jaundice, the erosion of the vulva, leucorrhea, ascarid, infantile malnutrition, hemorrhoid are swollen, eczema." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " diuresis.Control five types of stranguria nebulousurine, pyretic stranguria, the puckery key that closes the border of stasis of blood essence, and control married woman's stagnation of QI, damp and hot in stomach, or the disease of leucorrhea.”
Semen Plantaginis: Semen Plantaginis: sweet in the mouth, light, cold nature; Return lung, liver, kidney, urinary bladder channel." property of medicine is fallen " carries: " can remove pathogenic wind toxic, the liver affected by pathogenic wind heat, malicious wind dotting punch order, swelling pain is hidden from view, and headache lacrimation, removes irritable feverish sensation of chest and heart." modern medicine study confirmation, Herba Plantaginis clearing away heat and promoting diuresis, removing heat from blood, removing toxic substances.
Herba Dianthi: bitter in the mouth, cold in nature; GUIXIN, small intestine meridian.Inducing diuresis for treating stranguria syndrome, removing blood stasis stimulates the menstrual flow.For pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction, drenches the puckery pain of drop.Bencao Beiyao " carry: " fall heart-fire, sharp small intestinal, by bladder pathogenic heat, for controlling pouring key medicine.”
Endothelium Corneum Gigeriae Galli: sweet in the mouth, cold in nature; Return spleen, stomach, small intestinal, urinary bladder channel.Promoting digestion and invigorating the stomach, aid digestion, arresting seminal emission." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " alleviating distention in middle-JIAO spleen invigorating, mill stomach helps digestion.Control children's's breast food knot stagnant, the large muscle green grass or young crops of tripe, mass in the abdomen infantile malnutrition." modern medicine study confirmation, Endothelium Corneum Gigeriae Galli can promote gastric secretion, improves gastric acidity and eupepsy, stomach motor function is obviously strengthened, rapid gastric emptying.
Natrii Sulfas: salty in the mouth, hardship, cold in nature; Return stomach, lung, spleen, kidney, intestine and small intestine warp.Purging heat to relax the bowels, moistening for dryness and softening hard mass, the detumescence of relieving inflammation or internal heat.For excess-heat constipation, constipation due to dry stool, stagnant stomachache, acute appendicitis swells and ache, external treatment acute mastitis, swelling and pain of hemorrhoid.Modern medicine study confirmation, Natrii Sulfas can be used for treating the symptoms such as convulsions, eclamposia, uremia, tetanus, hypertensive encephalopathy and acut renal hypertension.
Rhizoma Sparganii: acrid in the mouth, puckery, cool in nature; Enter liver, spleen channel.Removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain, dysmenorrhea, amenorrhea, postnatal blood stasis stomachache, traumatic injury." Japan hanako materia medica " carries: " control married woman's blood vessels uncomfortable, cardiac and abdominal pain, the tire that falls, the stagnant blood that disappears, mends labor, logical menstruation, controls flatulence, disappear and flutter damage blood stasis, puerperal abdonimal pain, blood fortune stagnated blood not under.”
Semen Vaccariae: bitter in the mouth, property is flat; Return liver, stomach warp.Promoting the circulation of blood regulating menstruation, reducing swelling and alleviating pain, the lactogenesis of invigorating blood circulation, expedites the emergence of stimulating milk secretion, thymus dredging in puerperal.Cure mainly blood stasis amenorrhea, dysmenorrhea, difficult labour, lack of lactation after delivery, acute mastitis swells and ache, pyretic stranguria, stranguria with blood, stranguria caused by urinary stone.Modern medicine study confirmation, Semen Vaccariae has promoting blood circulation to restore menstrual flow, stimulating milk secretion eliminating carbuncle, the effect of inducing diuresis for treating stranguria syndrome.
Cortex Magnoliae Officinalis: bitter in the mouth, pungent, warm in nature; Return spleen, stomach, large intestine channel.Circulation of qi promoting removing food stagnancy, dampness is removed full, lowering the adverse QI to relieve asthma.Control stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant is stopped up QI rising in reverse order, and fullness in the chest is breathed with cough." Japan hanako materia medica " carries: " spleen invigorating, main regurgitation, cramp caused by acute vomiting and diarrhea, cold and hot gas, rushes down bladder, lets out all gas of five Tibetan, and married woman's abdomen in antenatal puerperal is hidden uneasy.Adjust joint, kill abdomen and hide worm, cloudy knowledge.”
Herba Cirsii: sweet in the mouth, hardship, cool in nature; GUIXIN, Liver Channel.Cooling blood for hemostasis, removing blood stasis to reduce swelling.For epistaxis, to spit blood, hematuria, has blood in stool, metrostaxis, traumatic hemorrhage, carbuncle sore tumefacting virus." Chinese herbal medicine is commonly used in Shanghai " carries: " heat clearing away, hemostasis, blood pressure lowering, dissipating blood stasis for subsidence of swelling.Control various hemorrhages, hypertension, jaundice, hepatitis, nephritis.”
Spina Gleditsiae: acrid in the mouth, warm in nature; Return lung, Liver Channel.Swollen ulcer drug, scrofula, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention, leprosy.Compendium of Material Medica is carried: " control carbuncle, acute mastitis, scrofula caused by pathogenic wind malignant boil, retention of placenta, parasite killing." research of modern Anticancer shows, Spina Gleditsiae has anticancer tumor-suppression activity.
Herba Crotalariae Ferrugineae: bitter in the mouth, micro-acid; Property is put down, is trembled with fear; Return lung meridian.Nourishing the kidney and liver, relieving cough and asthma, eliminating damp, detoxifying.Cure mainly tinnitus, deafness, the vertigo, seminal emission, menorrhagia, leucorrhea, chronic cough expectorant blood, asthma, nephritis, dysuria, tonsillitis, parotitis, furuncle swelling toxin." choosing of Yunnan Chinese herbal medicine " carries: " diuretic, antiinflammatory are relievingd asthma, cough-relieving.Control chronic nephritis, cystitis, chronic bronchitis, tonsillitis, lymphadenitis, renal calculus; Menoxenia, dysmenorrhea.”
Rhizoma Polygonati Odorati: sweet in the mouth, property is flat; Enter lung, stomach warp.Nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid.Cure mainly cough caused by dryness, chronic cough, the dry throat and mouth of the cloudy liquid consumption of calentura wound, interior-heat is quenched one's thirst, and deficiency of YIN diseases caused by exogenous pathogenic factor are dizzy dizzy, muscle arteries and veins spasm and pain.Supplement to the Herbal carries: " main clever, adjust vim and vigour, make us strong." modern medicine study confirms, tonification the five internal organs, nourish QI and blood, and flat benefit and moistening held concurrently except effect of wind heat.
Medulla Tetrapanacis: sweet in the mouth, light, cold nature; Enter lung, stomach warp.Clear snobbish water, lactogenesis.Cure mainly the puckery pain of stranguria, dysuria, edema, jaundice, damp-warm diseases, oliguria with reddish urine, puerperal, breast was few, amenorrhea, leukorrhagia.For hygropyrexia dark coloured urine, the puckery pain of gonorrhea, edema oliguria, agalactia." Changsha medicine solution " carries: " stimulate the menstrual flow and close, treat jaundice, eliminating carbuncle cellulitis, sharp nose carbuncle, except vexed.”
Herba Lysimachiae: sweet in the mouth, micro-hardship, cool in nature; Return liver, gallbladder, kidney, urinary bladder channel.Heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, dampness removing jaundice eliminating.Can be used for pyretic stranguria, husky pouring, urinates and puckeryly has a pain, jaundice dark coloured urine, carbuncle furuncle, venom, liver and bile stone, the diseases such as lithangiuria.Modern medicine study confirmation, these product mainly have calculus, antibacterial, antiinflammatory action containing phenolic constituent, and humoral immunization, cellular immunization are all had to inhibitory action.
Poria: sweet in the mouth, light, property is flat.Promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, relieves internal heat anticancer.Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.Modern medicine study confirmation, the contained pachymic acid of Poria has the effect of enhancing immunity, antitumor and calmness, blood sugar lowering etc., the gastrointestinal smooth muscle that can relax, gastric acid secretion inhibiting, prevents hepatic necrosis, antibacterial.
Folium Pyrrosiae: sweet in the mouth, hardship, cold nature; Return lung, urinary bladder channel.Inducing diuresis for treating stranguria syndrome, clearing away heat to stop bleeding.For pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction, drenches the puckery pain of drop, spits blood, epistaxis, hematuria, metrorrhagia, dyspnea and cough due to lung-heat.
The present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention has effect of anti-inflammatory analgetic, blood circulation promoting and blood stasis dispelling, promoting QI to circulate and dispersing the agglomeration of the pathogens, diuresis and expelling stone, is applicable to the renal calculus patient of the symptoms such as waist is ached, the whole body is weak, it is not smooth to urinate, hematuria, and evident in efficacy, has no side effect, with low cost.
2, Chinese medicine preparation compatibility of the present invention is rigorous, has supplementary kidney qi, increases the gasification function of bladder, impels urinary function normal, produces lithodialysis, calculus removing effect, and safe, is conducive to patient's symptom that eases the pain in time.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
55 parts of 55 parts of Endothelium Corneum Gigeriae Galli of 60 portions of Herba Dianthis of 65 portions of Semen Plantaginiss of Herba Polygoni Avicularis
45 parts of 45 parts of Cortex Magnoliae Officinalis of 50 parts of Semen Vaccariae of 50 parts of Rhizoma Sparganii of Natrii Sulfas
35 parts of 35 portions of Rhizoma Polygonati Odorati of 40 parts of Herba Crotalariae Ferrugineaes of 40 parts of Spina Gleditsiaes of Herba Cirsii
30 parts of 30 parts of Folium Pyrrosiaes of 35 parts of Poria of 40 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
Treat a preparation method for the Chinese medicine preparation of renal calculus, comprise following processing step:
(1) Herba Polygoni Avicularis, Semen Plantaginis and Herba Cirsii are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(2) Herba Dianthi, Rhizoma Sparganii, Semen Vaccariae, Cortex Magnoliae Officinalis, Herba Crotalariae Ferrugineae, Rhizoma Polygonati Odorati, Medulla Tetrapanacis, Poria and Folium Pyrrosiae are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.16, for subsequent use;
(3) Endothelium Corneum Gigeriae Galli and Natrii Sulfas are mixed, after mix homogeneously, carry out pulverization process, grind into powder, cross 160
Order fine powder, for subsequent use;
(4) Spina Gleditsiae and Herba Lysimachiae are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filter, and the thick paste that at 70 ℃ of simmer down tos, relative density is 1.15~1.18, for subsequent use;
(5) above-mentioned steps (1)~(4) prepared juice, thick paste and fine powder are mixed, make tablet, obtain the Chinese medicine preparation for the treatment of renal calculus of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, can fully recover 3~5 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
50 parts of 51 parts of Endothelium Corneum Gigeriae Galli of 56 portions of Herba Dianthis of 60 portions of Semen Plantaginiss of Herba Polygoni Avicularis
40 parts of 40 parts of Cortex Magnoliae Officinalis of 45 parts of Semen Vaccariae of 45 parts of Rhizoma Sparganii of Natrii Sulfas
30 parts of 30 portions of Rhizoma Polygonati Odorati of 35 parts of Herba Crotalariae Ferrugineaes of 35 parts of Spina Gleditsiaes of Herba Cirsii
25 parts of 25 parts of Folium Pyrrosiaes of 30 parts of Poria of 35 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
42 parts of 43 parts of Endothelium Corneum Gigeriae Galli of 48 portions of Herba Dianthis of 52 portions of Semen Plantaginiss of Herba Polygoni Avicularis
35 parts of 35 parts of Cortex Magnoliae Officinalis of 40 parts of Semen Vaccariae of 40 parts of Rhizoma Sparganii of Natrii Sulfas
28 parts of 28 portions of Rhizoma Polygonati Odorati of 32 parts of Herba Crotalariae Ferrugineaes of 33 parts of Spina Gleditsiaes of Herba Cirsii
20 parts of 23 parts of Folium Pyrrosiaes of 25 parts of Poria of 27 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
35 parts of 40 parts of Endothelium Corneum Gigeriae Galli of 40 portions of Herba Dianthis of 45 portions of Semen Plantaginiss of Herba Polygoni Avicularis
30 parts of 30 parts of Cortex Magnoliae Officinalis of 35 parts of Semen Vaccariae of 35 parts of Rhizoma Sparganii of Natrii Sulfas
25 parts of 25 portions of Rhizoma Polygonati Odorati of 30 parts of Herba Crotalariae Ferrugineaes of 30 parts of Spina Gleditsiaes of Herba Cirsii
15 parts of 20 parts of Folium Pyrrosiaes of 20 parts of Poria of 20 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
30 parts of 35 parts of Endothelium Corneum Gigeriae Galli of 35 portions of Herba Dianthis of 40 portions of Semen Plantaginiss of Herba Polygoni Avicularis
25 parts of 25 parts of Cortex Magnoliae Officinalis of 30 parts of Semen Vaccariae of 30 parts of Rhizoma Sparganii of Natrii Sulfas
20 parts of 20 portions of Rhizoma Polygonati Odorati of 25 parts of Herba Crotalariae Ferrugineaes of 25 parts of Spina Gleditsiaes of Herba Cirsii
10 parts of 15 parts of Folium Pyrrosiaes of 15 parts of Poria of 15 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of renal calculus, the routine clinical observation of renal calculus patient 200 that selection is made a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups, treatment group 100 examples, wherein male's 55 examples at random, women's 45 examples, 30~60 years old age, 45.4 years old mean age, the shortest person of the course of disease 1 month, elder 5 years, average 2.5 years.Matched group 100 examples, wherein male's 56 examples, women's 44 examples, 31~65 years old age, 46.7 years old mean age, the shortest person of the course of disease 2 months, elder 6 years, average 3.1 years.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, can fully recover 3~5 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Matched group is taken allopurinol tablet, oral, be grown up one time 1~3,2~3 times on the one, when half an hour ante cibum or stomachache attack, chew rear clothes, the person of being in a bad way is conventionally invalid.
3, efficacy determination:
(1) cure: B ultrasonic shows renal calculus discharge, noresidue in body, graft function is normal.
(2) effective: B ultrasonic demonstration renal calculus is dwindled, and renal function obviously improves.
(3) effective: B ultrasonic shows that renal calculus reduces to some extent, renal function improves or worsens without continuing.
(4) invalid: symptom, sign are without improvement, and renal function is without improvement.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 40 examples, effective 30 examples, effective 25 examples, invalid 5 examples, cure rate 40%, total effective rate 95%.
In matched group, cure 20 examples, effective 15 examples, effective 11 examples, invalid 54 examples, cure rate 20%, total effective rate 46%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, Wang, man, 32 years old, people from Nanjing, it is many one year that patient suffers from renal calculus, and in ultrasound diagnosis kidney, calculus is 1.7 × 0.8cm, calculus the smooth of the edge, often lumbago, when pain, having some medicine symptom can alleviate, after a while outbreak again, again and again outbreak.To our hospital afterwards, take Chinese medicine preparation of the present invention, take after 1 course for the treatment of, through ultrasound diagnosis, in its kidney, calculus is 1.0 × 0.5cm, and lumbago obviously alleviates, and then takes again after 2 courses for the treatment of, and through ultrasound diagnosis, in its kidney, calculus is all discharged.
2, poplar, female, 38 years old, Ningbo of Zhejiang people, patient right side back lumbar part angor, and to thigh root radiation, acute face dolorosa, groan, cold sweat, look into Right Lower Abdomen tenderness (+), kidney district, right side tenderness <++), percussion pain (++), tongue fur BOHUANG, stringy and tense pulse.Suddenly look into B ultrasonic: the no echo area of visible 1.3cmX3.9cm in right sinus renalis, the expansion of right ureter epimere, the strong echo group of interior visible diameter 0.5cm, rear accompanying sound shadow.Routine urinalysis: albumen trace, leukocyte 3~5/np, erythrocyte 20~30/np, is diagnosed as stranguria caused by urinary stone.Control, clearing away heat-damp and promoting diuresis treating stranguria with calculus, take the above-mentioned Chinese medicine preparation of the present invention, take after 1 course for the treatment of, discharge the calculus of one piece of Semen Glycines size with urine, take after 3 courses for the treatment of, patient's symptom, sign disappear, and x-ray plain film, B ultrasonic show that calculus shade disappears.
3, model, man, 43 years old, people from Changchun, Jilin, patient suffers from renal calculus more than three years, and waist and abdominal part are often understood paroxysmal pain, and after aggravating activities, pain will be shown effect sometimes, when serious, there will be lancinating pain, and pain can be radiated to groin sometimes.Through ultrasound diagnosis, in its kidney, there is 5, calculus, wherein 1.2 maximum × 0.7cm.To our hospital afterwards, take Chinese medicine preparation of the present invention, take after 1 course for the treatment of, through ultrasound diagnosis, calculus or 5 in its kidney, but calculus obviously diminishes, then took again after 1 course for the treatment of of Chinese medicine preparation of the present invention, through ultrasound diagnosis, calculus also has 3 in its kidney, but calculus obviously diminishes, and then takes again 1 course for the treatment of of Chinese medicine preparation of the present invention, through ultrasound diagnosis, in its kidney, calculus is all discharged.
4, high certain, female, 52 years old, people from Dezhou, Shandong, the frequent lumbago of patient, through ultrasound diagnosis, in kidney, have two calculus, one of them calculus is 0.7 × 0.5cm, and another is 0.6 × 0.8cm, take after 1 course for the treatment of of Chinese medicine preparation of the present invention, through ultrasound diagnosis, calculus is discharged substantially in its kidney, takes after 2 courses for the treatment of of Chinese medicine preparation of the present invention, through ultrasound diagnosis, in its kidney, calculus is all discharged.
5, what certain, man, 61 years old, Jinan, Shandong Province people.Patient fell ill before half a year, and gnawing pains take no rest always for right side of body, and the anti-inflammatory analgetic of taking medicine is invalid.Tell and learn through Mr. He, pain had 10 years, found in the past ureteral calculus, treated, and pain does not appear for 6,7 years in centre, and pain number of times was more frequent in recent years.Right ureter epimere calculus is found in clinical diagnosis, and renal calculus, with slight hydrops.Take after 4 courses for the treatment of of Chinese medicine preparation of the present invention, recovery from illness, ultrasound diagnosis is without calculus thing, and follow-up investigation has no recurrence.
6, Chen, female, 48 years old, people from Jiujiang.Patient suffers from intermittently ictal stomachache, interrupts and the sharp ache of urinating with urinating, and can accompany terminal hematuria simultaneously, and clinical diagnosis is renal calculus.Take 3 courses for the treatment of of Chinese medicine preparation of the present invention, the state of an illness alleviates, and continues to take 2 courses for the treatment of, and recovery from illness is followed the tracks of and had no recurrence.

Claims (5)

1. a Chinese medicine preparation for the treatment of renal calculus, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
25~60 parts of 30~60 parts of Endothelium Corneum Gigeriae Galli of 30~65 portions of Herba Dianthis of 35~70 portions of Semen Plantaginiss of Herba Polygoni Avicularis
20~50 parts of 20~50 parts of Cortex Magnoliae Officinalis of 25~55 parts of Semen Vaccariae of 25~55 parts of Rhizoma Sparganii of Natrii Sulfas
15~40 parts of 15~40 portions of Rhizoma Polygonati Odorati of 20~45 parts of Herba Crotalariae Ferrugineaes of 20~45 parts of Spina Gleditsiaes of Herba Cirsii
5~35 parts of 10~35 parts of Folium Pyrrosiaes of 10~40 parts of Poria of 10~45 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
2. a kind of Chinese medicine preparation for the treatment of renal calculus according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
30~55 parts of 35~55 parts of Endothelium Corneum Gigeriae Galli of 35~60 portions of Herba Dianthis of 40~65 portions of Semen Plantaginiss of Herba Polygoni Avicularis
25~45 parts of 25~45 parts of Cortex Magnoliae Officinalis of 30~50 parts of Semen Vaccariae of 30~50 parts of Rhizoma Sparganii of Natrii Sulfas
20~35 parts of 20~35 portions of Rhizoma Polygonati Odorati of 25~40 parts of Herba Crotalariae Ferrugineaes of 25~40 parts of Spina Gleditsiaes of Herba Cirsii
10~30 parts of 15~30 parts of Folium Pyrrosiaes of 15~35 parts of Poria of 15~40 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
3. a kind of Chinese medicine preparation for the treatment of renal calculus according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
35~50 parts of 40~51 parts of Endothelium Corneum Gigeriae Galli of 40~56 portions of Herba Dianthis of 45~60 portions of Semen Plantaginiss of Herba Polygoni Avicularis
30~40 parts of 30~40 parts of Cortex Magnoliae Officinalis of 35~45 parts of Semen Vaccariae of 35~45 parts of Rhizoma Sparganii of Natrii Sulfas
25~30 parts of 25~30 portions of Rhizoma Polygonati Odorati of 30~35 parts of Herba Crotalariae Ferrugineaes of 30~35 parts of Spina Gleditsiaes of Herba Cirsii
15~25 parts of 20~25 parts of Folium Pyrrosiaes of 20~30 parts of Poria of 20~35 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
4. a kind of Chinese medicine preparation for the treatment of renal calculus according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
42 parts of 43 parts of Endothelium Corneum Gigeriae Galli of 48 portions of Herba Dianthis of 52 portions of Semen Plantaginiss of Herba Polygoni Avicularis
35 parts of 35 parts of Cortex Magnoliae Officinalis of 40 parts of Semen Vaccariae of 40 parts of Rhizoma Sparganii of Natrii Sulfas
28 parts of 28 portions of Rhizoma Polygonati Odorati of 32 parts of Herba Crotalariae Ferrugineaes of 33 parts of Spina Gleditsiaes of Herba Cirsii
20 parts of 23 parts of Folium Pyrrosiaes of 25 parts of Poria of 27 portions of Herba Lysimachiaes of Medulla Tetrapanacis.
5. a preparation method for the treatment of the Chinese medicine preparation of renal calculus as described in claim 1~4 any one, is characterized in that: comprise following processing step:
(1) Herba Polygoni Avicularis, Semen Plantaginis and Herba Cirsii are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(2) Herba Dianthi, Rhizoma Sparganii, Semen Vaccariae, Cortex Magnoliae Officinalis, Herba Crotalariae Ferrugineae, Rhizoma Polygonati Odorati, Medulla Tetrapanacis, Poria and Folium Pyrrosiae are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.16, for subsequent use;
(3) Endothelium Corneum Gigeriae Galli and Natrii Sulfas are mixed, after mix homogeneously, carry out pulverization process, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Spina Gleditsiae and Herba Lysimachiae are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filter, and the thick paste that at 70 ℃ of simmer down tos, relative density is 1.15~1.18, for subsequent use;
(5) above-mentioned steps (1)~(4) prepared juice, thick paste and fine powder are mixed, make tablet, obtain the Chinese medicine preparation for the treatment of renal calculus of the present invention.
CN201410143500.0A 2014-04-10 2014-04-10 Chinese medicinal preparation for treating renal calculus and preparation method thereof Expired - Fee Related CN103877457B (en)

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CN106421602A (en) * 2016-10-26 2017-02-22 惠安县泰达商贸有限责任公司 Traditional Chinese medicine preparation for treating kidney stone and preparation method and application thereof

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* Cited by examiner, † Cited by third party
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CN105169180A (en) * 2015-09-18 2015-12-23 马鞍山德宏堂生物科技有限公司 Traditional Chinese medicine decoction for treating biliary calculi
CN106421602A (en) * 2016-10-26 2017-02-22 惠安县泰达商贸有限责任公司 Traditional Chinese medicine preparation for treating kidney stone and preparation method and application thereof

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