CN1034806C - 制备嘧啶三酮衍生物的方法 - Google Patents

制备嘧啶三酮衍生物的方法 Download PDF

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Publication number
CN1034806C
CN1034806C CN91101394A CN91101394A CN1034806C CN 1034806 C CN1034806 C CN 1034806C CN 91101394 A CN91101394 A CN 91101394A CN 91101394 A CN91101394 A CN 91101394A CN 1034806 C CN1034806 C CN 1034806C
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CN
China
Prior art keywords
formula
compound
reaction
water
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN91101394A
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English (en)
Chinese (zh)
Other versions
CN1054592A (zh
Inventor
金德里·瓦茨塔
卡尔·瓦耳特
伯纳德·瑟福里得
瑟特番·胡根通博勒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sapos S
Original Assignee
Sapos S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sapos S filed Critical Sapos S
Publication of CN1054592A publication Critical patent/CN1054592A/zh
Application granted granted Critical
Publication of CN1034806C publication Critical patent/CN1034806C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Dental Preparations (AREA)
CN91101394A 1990-02-08 1991-02-08 制备嘧啶三酮衍生物的方法 Expired - Fee Related CN1034806C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9002890 1990-02-08
GB909002890A GB9002890D0 (en) 1990-02-08 1990-02-08 Process for preparing pyrimidinetrione derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN95106059A Division CN1121070A (zh) 1990-02-08 1995-05-12 制备嘧啶三酮衍生物的方法

Publications (2)

Publication Number Publication Date
CN1054592A CN1054592A (zh) 1991-09-18
CN1034806C true CN1034806C (zh) 1997-05-07

Family

ID=10670669

Family Applications (2)

Application Number Title Priority Date Filing Date
CN91101394A Expired - Fee Related CN1034806C (zh) 1990-02-08 1991-02-08 制备嘧啶三酮衍生物的方法
CN95106059A Pending CN1121070A (zh) 1990-02-08 1995-05-12 制备嘧啶三酮衍生物的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN95106059A Pending CN1121070A (zh) 1990-02-08 1995-05-12 制备嘧啶三酮衍生物的方法

Country Status (26)

Country Link
US (1) US5262402A (enExample)
EP (1) EP0466887B1 (enExample)
JP (1) JPH04505460A (enExample)
KR (1) KR920701173A (enExample)
CN (2) CN1034806C (enExample)
AT (1) ATE113589T1 (enExample)
BG (1) BG60269B1 (enExample)
CA (1) CA2049991A1 (enExample)
CS (1) CS31191A3 (enExample)
DE (1) DE69104920T2 (enExample)
DK (1) DK0466887T3 (enExample)
ES (1) ES2065002T3 (enExample)
GB (1) GB9002890D0 (enExample)
GE (1) GEP19970892B (enExample)
HR (1) HRP950155A2 (enExample)
HU (2) HUT64077A (enExample)
IE (1) IE62606B1 (enExample)
LT (1) LT3316B (enExample)
LV (1) LV10259B (enExample)
PL (2) PL168051B1 (enExample)
PT (1) PT96694B (enExample)
RO (1) RO109334B1 (enExample)
RU (1) RU2050353C1 (enExample)
TW (1) TW216792B (enExample)
WO (1) WO1991012244A1 (enExample)
YU (1) YU47836B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2107064A1 (de) * 2008-04-02 2009-10-07 Basf Se Verfahren zur Herstellung von Triamiden aus Ammoniak und Amido-Dichloriden

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0125046A1 (en) * 1983-04-12 1984-11-14 Sapos S.A. Process for preparing pyrimidinetrione derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2051846A (en) * 1936-08-25 Production of barbituric acid
US2876225A (en) * 1959-03-03 Manufacture of therapeutic substances
US2161212A (en) * 1939-06-06 Substituted barbituric acids con
US814496A (en) * 1904-11-08 1906-03-06 Firm Of E Merck Process of making barbituric acids.
GB1581834A (en) 1976-11-01 1980-12-31 Sapos Sa Complexes of barbituric acid derivatives
FR2424262A1 (fr) * 1978-04-24 1979-11-23 Sapos Sa Nouveaux complexes tetrameres de derives de la malonyl-uree a action psychotrope et procede de preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0125046A1 (en) * 1983-04-12 1984-11-14 Sapos S.A. Process for preparing pyrimidinetrione derivatives

Also Published As

Publication number Publication date
LV10259B (en) 1995-08-20
HRP950155A2 (en) 1996-06-30
YU21791A (sh) 1994-04-05
HUT59380A (en) 1992-05-28
LV10259A (lv) 1994-10-20
US5262402A (en) 1993-11-16
HU913183D0 (en) 1992-02-28
HU207722B (en) 1993-05-28
BG60269B2 (en) 1994-03-31
JPH04505460A (ja) 1992-09-24
DK0466887T3 (da) 1994-12-27
HU9300285D0 (en) 1993-04-28
KR920701173A (ko) 1992-08-11
LT3316B (en) 1995-06-26
BG60269B1 (bg) 1994-03-31
DE69104920D1 (de) 1994-12-08
PL168051B1 (pl) 1995-12-30
EP0466887B1 (en) 1994-11-02
PL292559A1 (enExample) 1993-02-08
YU47836B (sr) 1996-01-09
LTIP612A (en) 1994-12-25
ATE113589T1 (de) 1994-11-15
CN1121070A (zh) 1996-04-24
RO109334B1 (ro) 1995-01-30
IE62606B1 (en) 1995-02-22
PL165990B1 (pl) 1995-03-31
DE69104920T2 (de) 1995-03-16
HUT64077A (en) 1993-11-29
PT96694A (pt) 1991-10-31
PT96694B (pt) 1998-07-31
GEP19970892B (en) 1997-04-15
IE910409A1 (en) 1991-08-14
CA2049991A1 (en) 1991-08-09
ES2065002T3 (es) 1995-02-01
WO1991012244A1 (en) 1991-08-22
RU2050353C1 (ru) 1995-12-20
GB9002890D0 (en) 1990-04-04
CS31191A3 (en) 1992-02-19
CN1054592A (zh) 1991-09-18
TW216792B (enExample) 1993-12-01
EP0466887A1 (en) 1992-01-22

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee