LTIP612A - Process for the preparing pyrimidinetrione derivatives - Google Patents

Process for the preparing pyrimidinetrione derivatives

Info

Publication number
LTIP612A
LTIP612A LTIP612A LTIP612A LTIP612A LT IP612 A LTIP612 A LT IP612A LT IP612 A LTIP612 A LT IP612A LT IP612 A LTIP612 A LT IP612A LT IP612 A LTIP612 A LT IP612A
Authority
LT
Lithuania
Prior art keywords
pct
sec
derivatives
pyrimidinetrione derivatives
relates
Prior art date
Application number
LTIP612A
Inventor
Bernard Siegfried
Jindrich Vachta
Karel Valter
Stephane Hugentobler
Original Assignee
Sapos Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sapos Sa filed Critical Sapos Sa
Publication of LTIP612A publication Critical patent/LTIP612A/en
Publication of LT3316B publication Critical patent/LT3316B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Dental Preparations (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PCT No. PCT/EP91/00253 Sec. 371 Date Oct. 30, 1991 Sec. 102(e) Date Oct. 30, 1991 PCT Filed Feb. 5, 1991 PCT Pub. No. WO91/12244 PCT Pub. Date Aug. 22, 1991.This invention relates to a process for preparation of pyrimidinetriones. It also relates to novel N-dihydroxyphosphoryl pyrimidinetrione derivatives which may be useful as water-soluble prodrugs of certain pyrimidinetrione compounds.
LTIP612A 1990-02-08 1993-06-03 Process for preparing pyrimidinetrione derivatives LT3316B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909002890A GB9002890D0 (en) 1990-02-08 1990-02-08 Process for preparing pyrimidinetrione derivatives

Publications (2)

Publication Number Publication Date
LTIP612A true LTIP612A (en) 1994-12-25
LT3316B LT3316B (en) 1995-06-26

Family

ID=10670669

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP612A LT3316B (en) 1990-02-08 1993-06-03 Process for preparing pyrimidinetrione derivatives

Country Status (26)

Country Link
US (1) US5262402A (en)
EP (1) EP0466887B1 (en)
JP (1) JPH04505460A (en)
KR (1) KR920701173A (en)
CN (2) CN1034806C (en)
AT (1) ATE113589T1 (en)
BG (1) BG60269B2 (en)
CA (1) CA2049991A1 (en)
CS (1) CS31191A3 (en)
DE (1) DE69104920T2 (en)
DK (1) DK0466887T3 (en)
ES (1) ES2065002T3 (en)
GB (1) GB9002890D0 (en)
GE (1) GEP19970892B (en)
HR (1) HRP950155A2 (en)
HU (2) HUT64077A (en)
IE (1) IE62606B1 (en)
LT (1) LT3316B (en)
LV (1) LV10259B (en)
PL (2) PL165990B1 (en)
PT (1) PT96694B (en)
RO (1) RO109334B1 (en)
RU (1) RU2050353C1 (en)
TW (1) TW216792B (en)
WO (1) WO1991012244A1 (en)
YU (1) YU47836B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2107064A1 (en) * 2008-04-02 2009-10-07 Basf Se Method for producing triamides from ammonia and amido-dichlorides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2051846A (en) * 1936-08-25 Production of barbituric acid
US2161212A (en) * 1939-06-06 Substituted barbituric acids con
US2876225A (en) * 1959-03-03 Manufacture of therapeutic substances
US814496A (en) * 1904-11-08 1906-03-06 Firm Of E Merck Process of making barbituric acids.
GB1581834A (en) 1976-11-01 1980-12-31 Sapos Sa Complexes of barbituric acid derivatives
FR2424262A1 (en) * 1978-04-24 1979-11-23 Sapos Sa Anti-tremor and anti-anxiety malonylurea tetramer complex cpds. - prepd. by reacting barbiturate derivs. with n-substd. barbituric acid cpds. (BE 2.5.78)
GB8309813D0 (en) * 1983-04-12 1983-05-18 Sapos Sa Pyrimidinetrione derivatives

Also Published As

Publication number Publication date
BG60269B1 (en) 1994-03-31
RO109334B1 (en) 1995-01-30
HUT64077A (en) 1993-11-29
HU9300285D0 (en) 1993-04-28
HUT59380A (en) 1992-05-28
BG60269B2 (en) 1994-03-31
PT96694B (en) 1998-07-31
EP0466887B1 (en) 1994-11-02
HRP950155A2 (en) 1996-06-30
CA2049991A1 (en) 1991-08-09
WO1991012244A1 (en) 1991-08-22
PT96694A (en) 1991-10-31
ATE113589T1 (en) 1994-11-15
JPH04505460A (en) 1992-09-24
HU207722B (en) 1993-05-28
DK0466887T3 (en) 1994-12-27
PL292559A1 (en) 1993-02-08
PL168051B1 (en) 1995-12-30
RU2050353C1 (en) 1995-12-20
ES2065002T3 (en) 1995-02-01
LV10259B (en) 1995-08-20
CN1034806C (en) 1997-05-07
KR920701173A (en) 1992-08-11
YU47836B (en) 1996-01-09
CS31191A3 (en) 1992-02-19
DE69104920D1 (en) 1994-12-08
IE62606B1 (en) 1995-02-22
PL165990B1 (en) 1995-03-31
LV10259A (en) 1994-10-20
US5262402A (en) 1993-11-16
DE69104920T2 (en) 1995-03-16
CN1121070A (en) 1996-04-24
YU21791A (en) 1994-04-05
CN1054592A (en) 1991-09-18
EP0466887A1 (en) 1992-01-22
GB9002890D0 (en) 1990-04-04
GEP19970892B (en) 1997-04-15
TW216792B (en) 1993-12-01
LT3316B (en) 1995-06-26
IE910409A1 (en) 1991-08-14
HU913183D0 (en) 1992-02-28

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Legal Events

Date Code Title Description
MM9A Lapsed patents

Effective date: 19970603