CN103443614B - 信号增强化合物在电化学发光检测中的用途 - Google Patents
信号增强化合物在电化学发光检测中的用途 Download PDFInfo
- Publication number
- CN103443614B CN103443614B CN201180062441.9A CN201180062441A CN103443614B CN 103443614 B CN103443614 B CN 103443614B CN 201180062441 A CN201180062441 A CN 201180062441A CN 103443614 B CN103443614 B CN 103443614B
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- PCXJASANFWPUMO-UHFFFAOYSA-N CCC(NC)O Chemical compound CCC(NC)O PCXJASANFWPUMO-UHFFFAOYSA-N 0.000 description 1
- PYFSCIWXNSXGNS-YFKPBYRVSA-N CC[C@H](C)NC Chemical compound CC[C@H](C)NC PYFSCIWXNSXGNS-YFKPBYRVSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/04—Preparation
- C07D499/10—Modification of an amino radical directly attached in position 6
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Plasma & Fusion (AREA)
- Fluid Mechanics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10188716.4 | 2010-10-25 | ||
| EP10188716 | 2010-10-25 | ||
| EP10192106 | 2010-11-22 | ||
| EP10192106.2 | 2010-11-22 | ||
| PCT/EP2011/068540 WO2012055815A1 (en) | 2010-10-25 | 2011-10-24 | Use of signal enhancing compounds in electrochemiluminescence detection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103443614A CN103443614A (zh) | 2013-12-11 |
| CN103443614B true CN103443614B (zh) | 2015-07-22 |
Family
ID=44860372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180062441.9A Active CN103443614B (zh) | 2010-10-25 | 2011-10-24 | 信号增强化合物在电化学发光检测中的用途 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9341575B2 (enExample) |
| EP (1) | EP2633289B1 (enExample) |
| JP (1) | JP5824523B2 (enExample) |
| KR (1) | KR101789356B1 (enExample) |
| CN (1) | CN103443614B (enExample) |
| AU (1) | AU2011322704B2 (enExample) |
| BR (1) | BR112013007614B1 (enExample) |
| CA (1) | CA2813089C (enExample) |
| DK (1) | DK2633289T3 (enExample) |
| ES (1) | ES2581553T3 (enExample) |
| HU (1) | HUE029030T2 (enExample) |
| MX (1) | MX336940B (enExample) |
| PL (1) | PL2633289T3 (enExample) |
| SG (1) | SG189113A1 (enExample) |
| WO (1) | WO2012055815A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106153953A (zh) * | 2015-04-03 | 2016-11-23 | 盐城拜明生物技术有限公司 | 一种用于检测血清样品中叶酸含量的叶酸释放剂 |
| JP7039481B2 (ja) | 2016-03-11 | 2022-03-22 | エフ.ホフマン-ラ ロシュ アーゲー | 電気化学発光検出における分枝鎖アミン |
| CN106124753B (zh) * | 2016-07-08 | 2018-03-06 | 广州东林生物科技有限公司 | 电化学发光缓冲液及清洗液 |
| CN108375571B (zh) * | 2018-02-05 | 2019-11-26 | 苏州长光华医生物医学工程有限公司 | 一种用于化学发光免疫检测的磁颗粒试剂及试剂盒 |
| AU2019418498A1 (en) * | 2019-01-03 | 2021-07-15 | Meso Scale Technologies, Llc | Compositions and methods for carrying out assay measurements |
| EP4006529A4 (en) * | 2019-07-31 | 2023-01-18 | Hitachi High-Tech Corporation | METHOD AND DEVICE FOR THE ANALYSIS OF BIOMOLECULES |
| CN115518417B (zh) * | 2022-09-01 | 2024-09-06 | 天津鸿宇泰生物科技有限公司 | 用于化学发光检测试剂的消泡剂组合物、使用方法和应用 |
| CN115494232B (zh) * | 2022-10-31 | 2023-10-27 | 江苏三联生物工程股份有限公司 | 4,4-二甲基噁唑啉在制备含辣根过氧化物酶的试剂中的应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4002456A (en) * | 1974-03-08 | 1977-01-11 | U.S. Philips Corporation | Plant-growth promoting agent which is provided with trace elements and which is suited for use in ultra-low-volume applications |
| US5677192A (en) * | 1993-05-03 | 1997-10-14 | Boehringer Mannheim Gmbh | Electrochemiluminescence assay |
| CN101246125A (zh) * | 2008-03-14 | 2008-08-20 | 华南师范大学 | 基于纳米/微米粒子放大信号的非pcr扩增的快速检测转基因产品的电化学发光方法 |
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| US4698302A (en) | 1983-05-12 | 1987-10-06 | Advanced Magnetics, Inc. | Enzymatic reactions using magnetic particles |
| US4628037A (en) | 1983-05-12 | 1986-12-09 | Advanced Magnetics, Inc. | Binding assays employing magnetic particles |
| US4554088A (en) | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
| US4695393A (en) | 1983-05-12 | 1987-09-22 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
| US5310687A (en) | 1984-10-31 | 1994-05-10 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5591581A (en) | 1986-04-30 | 1997-01-07 | Igen, Inc. | Electrochemiluminescent rhenium moieties and methods for their use |
| US6165729A (en) | 1986-04-30 | 2000-12-26 | Hyperion Catalysis International, Inc. | Electrochemiluminescent reaction utilizing amine-derived reductant |
| US6316607B1 (en) | 1986-04-30 | 2001-11-13 | Igen International, Inc. | Electrochemiluminescent assays |
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| US5935779A (en) | 1988-11-03 | 1999-08-10 | Igen International Inc. | Methods for improved particle electrochemiluminescence assay |
| US5204244A (en) | 1987-10-27 | 1993-04-20 | Oncogen | Production of chimeric antibodies by homologous recombination |
| US5202238A (en) | 1987-10-27 | 1993-04-13 | Oncogen | Production of chimeric antibodies by homologous recombination |
| US5308754A (en) | 1988-03-21 | 1994-05-03 | Kankare Jouko J | Electrogenerated luminescence in solution |
| US5093268A (en) | 1988-04-28 | 1992-03-03 | Igen, Inc. | Apparatus for conducting a plurality of simultaneous measurements of electrochemiluminescent phenomena |
| US5705402A (en) | 1988-11-03 | 1998-01-06 | Igen International, Inc. | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
| US5779976A (en) * | 1988-11-03 | 1998-07-14 | Igen International, Inc. | Apparatus for improved luminescence assays |
| CA2002083C (en) | 1988-11-03 | 2001-01-09 | Haresh P. Shah | Enhanced electrochemiluminescence |
| US5324457A (en) | 1989-10-02 | 1994-06-28 | Board Of Regents, The University Of Tx System | Devices and methods for generating electrogenerated chemiluminescence |
| JPH0534345A (ja) | 1991-02-19 | 1993-02-09 | Tdk Corp | 化学発光を利用する抗原・抗体の測定方法 |
| ZA929351B (en) | 1991-12-11 | 1993-06-04 | Igen Inc | Electrochemiluminescent label for DNA assays. |
| JP3541047B2 (ja) * | 1993-02-18 | 2004-07-07 | 日本化薬株式会社 | バイオリアクターの防腐剤および測定法 |
| DE4401577A1 (de) * | 1993-05-03 | 1994-11-10 | Boehringer Mannheim Gmbh | Elektrochemilumineszenzverfahren |
| US5466416A (en) | 1993-05-14 | 1995-11-14 | Ghaed; Ali | Apparatus and methods for carrying out electrochemiluminescence test measurements |
| CN1046531C (zh) | 1994-07-25 | 1999-11-17 | 伯伦格·曼海姆有限公司 | 有带电连接基的金属配合物、轭合物及其用途和制备方法 |
| US5786141A (en) | 1994-08-26 | 1998-07-28 | Bard; Allen J. | Electrogenerated chemiluminescence labels for analysis and/or referencing |
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| US5641623A (en) | 1995-01-04 | 1997-06-24 | Martin; Mark T. | Electrochemiluminescence assay |
| US5643713A (en) | 1995-06-07 | 1997-07-01 | Liang; Pam | Electrochemiluminescent monitoring of compounds |
| US20010003647A1 (en) | 1995-06-07 | 2001-06-14 | Ji Sun | Coreatant-including electrochemiluminescent compounds, methods, systems and kits utilizing same |
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| FR2764381A1 (fr) | 1997-06-09 | 1998-12-11 | Univ De Neuchatel | Detecteur electrochimioluminescent |
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| DE19803528A1 (de) | 1998-01-30 | 1999-08-05 | Roche Diagnostics Gmbh | Verfahren zur Analyse einer Probe mittels eines Elektrochemolumineszenz-Bindungsreaktion-Tests |
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| FI119894B (fi) * | 2005-03-30 | 2009-04-30 | Labmaster Oy | Elektrokemiluminesenssiin perustuva analyysimenetelmä ja siinä käytettävä laite |
| US20070116600A1 (en) * | 2005-06-23 | 2007-05-24 | Kochar Manish S | Detection device and methods associated therewith |
| KR101489804B1 (ko) | 2005-12-21 | 2015-02-05 | 메소 스케일 테크놀러지즈, 엘엘시 | 분석 시약을 갖는 분석 모듈 및 그것의 제조 및 사용 방법 |
| ATE530895T1 (de) | 2006-08-25 | 2011-11-15 | Hoffmann La Roche | Zelle zur durchführung elektrochemilumineszenter messungen |
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| FI20100246A7 (fi) * | 2010-06-11 | 2011-12-12 | Jarkko Eskola | Menetelmät ja laitteet luminesenssin tuottamiseksi integroiduista elektrodisiruista katodisten ja bipolaaristen pulssien avulla |
-
2011
- 2011-10-24 ES ES11774051.4T patent/ES2581553T3/es active Active
- 2011-10-24 CN CN201180062441.9A patent/CN103443614B/zh active Active
- 2011-10-24 WO PCT/EP2011/068540 patent/WO2012055815A1/en not_active Ceased
- 2011-10-24 CA CA2813089A patent/CA2813089C/en active Active
- 2011-10-24 MX MX2013004230A patent/MX336940B/es active IP Right Grant
- 2011-10-24 DK DK11774051.4T patent/DK2633289T3/en active
- 2011-10-24 SG SG2013022553A patent/SG189113A1/en unknown
- 2011-10-24 AU AU2011322704A patent/AU2011322704B2/en not_active Ceased
- 2011-10-24 BR BR112013007614-3A patent/BR112013007614B1/pt not_active IP Right Cessation
- 2011-10-24 HU HUE11774051A patent/HUE029030T2/en unknown
- 2011-10-24 JP JP2013535387A patent/JP5824523B2/ja active Active
- 2011-10-24 EP EP11774051.4A patent/EP2633289B1/en active Active
- 2011-10-24 KR KR1020137009849A patent/KR101789356B1/ko not_active Expired - Fee Related
- 2011-10-24 PL PL11774051.4T patent/PL2633289T3/pl unknown
-
2013
- 2013-03-15 US US13/844,778 patent/US9341575B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4002456A (en) * | 1974-03-08 | 1977-01-11 | U.S. Philips Corporation | Plant-growth promoting agent which is provided with trace elements and which is suited for use in ultra-low-volume applications |
| US5677192A (en) * | 1993-05-03 | 1997-10-14 | Boehringer Mannheim Gmbh | Electrochemiluminescence assay |
| CN1089899C (zh) * | 1993-05-03 | 2002-08-28 | 罗赫诊断器材股份有限公司 | 电致化学发光分析 |
| CN101246125A (zh) * | 2008-03-14 | 2008-08-20 | 华南师范大学 | 基于纳米/微米粒子放大信号的非pcr扩增的快速检测转基因产品的电化学发光方法 |
Non-Patent Citations (1)
| Title |
|---|
| Electrochemiluminescent labels for applications in fully aqueous solutions at oxide-covered aluminium electrodes;S. Kulmala et al.;《Analytica Chimica Acta》;19991231;第386卷;1-6 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012055815A1 (en) | 2012-05-03 |
| DK2633289T3 (en) | 2016-06-06 |
| US20130224758A1 (en) | 2013-08-29 |
| AU2011322704B2 (en) | 2014-12-11 |
| AU2011322704A1 (en) | 2013-03-21 |
| CA2813089A1 (en) | 2012-05-03 |
| CA2813089C (en) | 2018-02-20 |
| MX336940B (es) | 2016-02-08 |
| CN103443614A (zh) | 2013-12-11 |
| MX2013004230A (es) | 2013-05-30 |
| BR112013007614B1 (pt) | 2020-12-29 |
| BR112013007614A2 (pt) | 2018-05-02 |
| ES2581553T3 (es) | 2016-09-06 |
| HK1188826A1 (en) | 2014-05-16 |
| EP2633289B1 (en) | 2016-04-20 |
| JP2013542436A (ja) | 2013-11-21 |
| JP5824523B2 (ja) | 2015-11-25 |
| SG189113A1 (en) | 2013-05-31 |
| KR101789356B1 (ko) | 2017-10-23 |
| PL2633289T3 (pl) | 2016-12-30 |
| HUE029030T2 (en) | 2017-01-30 |
| KR20140012940A (ko) | 2014-02-04 |
| EP2633289A1 (en) | 2013-09-04 |
| US9341575B2 (en) | 2016-05-17 |
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