CN103416629A - Pig feed additive capable of effectively improving pig immunity and promoting pig growth - Google Patents
Pig feed additive capable of effectively improving pig immunity and promoting pig growth Download PDFInfo
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Abstract
The invention provides a pig feed additive capable of effectively improving pig immunity and promoting pig growth. The pig feed additive is composed of astragalus polysaccharide, acanthopanax powder, fermented traditional Chinese medicine powder, muskmelon pedicel powder, tangerine peel powder and the rest carrier, the carrier is a mixture of wheat bran and defatted rice bran at a mass ratio of 1:1. The pig feed additive can remarkably lower incidence of pigs, improve immunity of the pigs and increase growth rate of the pigs, can replace or partly replace application of chemosynthesis additives in feed and has wide market prospect.
Description
Technical field
The present invention relates to a kind of pig's feed additive, especially relate to a kind of feed addictive that can effectively strengthen immunity and promote the pig growth, be applicable to the production of pig perfect compound feed, belong to feed additive field.
Background technology
In recent years, the various food securities that caused by additive are in the news in a large number, one the time whole society in commotion, make us greatly alarmed, brought certain de-stabilising effect to society.Along with improving constantly of social development and people's living standard, know-how, pursue the step of the food of safety, nutrition and will constantly accelerate, also will strengthen the concern dynamics to problem close examination and the research of additive.Feed addictive is the important substance prerequisite of modern feed industry production, it is based on different purpose (as supplemented essential nutrient, strengthen immunity, increase and search for food, promote to grow, improve feed efficiency, improve feed and livestock products quality etc.) and is added on the different material in mixed feed, mainly comprises chemical synthesis additive and natural additive.At present feedstuff industry mainly be take the chemical synthesis additive as main, mainly comprises antibiotic, hormone, chemical synthetic drug etc., and it is widely used in controls with growth promotion etc. in advance, and the development of feed industry and animal husbandry is played to the effect of actively promoting.Yet along with deepening continuously of research, it is found that under cover huge drawback of behind that the chemical synthesis additive brings the tremendous economic interests, as excessive use antibiotic can cause the quality of animal meat product and product thereof to descend and the enhancing of antibiotic patience, to the mankind, brought serious potential safety hazard.Some country has started the explicit order restriction or forbidden adding some chemical synthesis additives in feed, European Union is by corresponding rules, European Union will carry out the EU-25 decree in January, 2006, forbid adding the feeding antibiotic for the growth promotion purpose in pig feed.
Natural additive refers to from plant or microbial metabolic products and to separate the material obtained, possess safe, toxic and side effect is little, without characteristics such as the resistances to the action of a drug, have simultaneously trophism, antimicrobial, strengthen the function such as immunity.How developing natural additive has become the focus of the industry research such as food and feed.
Summary of the invention
The object of the invention be to provide a kind of cheap, produce and use simply, effectively strengthen immunity and somatotrophic pig feed additive.
The pig feed additive of a kind of effective enhancing immunity and promotion growth, every 100 parts are added following additives by following weight proportion: astragalus polyose 8-12 part, wilsonii powder 6-10 part, fermentation of Chinese herbal medicine powder 6-8 part, muskmelon pedicel powder 3-5 part, dried orange peel powder 4-5 part, all the other are carrier.The mixture that carrier is wheat bran and defatted rice bran, 1:1 mixes in mass ratio.
The preparation method of described astragalus polyose:
Step 1: by Radix Astragali drying and crushing, cross 40 mesh sieves, by solid-liquid ratio 1:(20-30) add deionized water, add the cellulase of 0.1%-0.2%, stir ultrasonic extraction 20-30 minute after 10-20 minute, ultrasonic power 80-100W, temperature 30-45 ℃; Vacuum filtration, get filtrate, in filtrate, adds absolute ethyl alcohol, and making concentration of alcohol is 65-85%, 10-15 ℃ of precipitation 1-2h, taking precipitate;
Step 2: sediment and deionized water are pressed to 1:(3-4) wiring solution-forming, add active carbon and the diatomite 15-20 minute that decoloured by liquid-solid ratio 5:1, filters and remove active carbon and diatomite, and Vacuum Concentration is to the 1/5-1/6 of original volume; Wherein active carbon and diatomite are pressed the 1:1 mixing;
Step 3: the extract of processing through decolouring in step 2 is joined in the chromatographic column that macroreticular resin is housed, standing 1h, the ethanol elution with 26%, collect eluent, concentrated, and spray-drying is pulverized, and crosses 60 mesh sieves, obtains astragalus polyose; Wherein macroreticular resin is AB-8.
The preparation method of described wilsonii powder: put into-60 ℃ to-80 ℃ of freezing 12h after wilsonii is cleaned, take out and put into-40 ℃ to-55 ℃ of lower freeze dryings; After drying is complete, wilsonii is carried out to coarse crushing, and then adopt superfine communication technique to be pulverized, obtain the wilsonii powder.
Described composite Chinese herbal fermentate preparation method: by selected dry Radix Codonopsis, Radix Glycyrrhizae and root of kudzu vine chopping, with 75% the ethanol even sterilization of spraying, through 60-80 ℃ of oven dry, pulverized 40 mesh sieves, obtain mix powder, add 8 times of weight water in mix powder and control temperature to 55 ℃, the mixed enzyme that adds 0.1-0.3%, mixed enzyme is pectase and cellulase, enzymolysis 2h, after enzymolysis toward adding the glucose of weight 0.5% in mixture, 0.1% magnesium sulfate, 0.5% sodium sulphate and 0.2% beef extract, add CICC10063 bacillus subtilis and lactobacillus bulgaricus seed liquor in fermentation medium.CICC10063 bacillus subtilis inoculum concentration is 2-3%, and the lactobacillus bulgaricus inoculum concentration is 4-5%, temperature 30-35 ℃, fermentation 24-48h; Then adopt the vacuum drying mode to carry out drying, crushed after being dried is crossed 40 mesh sieves;
The mass ratio of described dry Radix Codonopsis, Radix Glycyrrhizae and the root of kudzu vine is 1:(3-5): (4-5);
The mass ratio of described pectase and cellulase is 1:(2-3);
Described muskmelon pedicel powder, preparation method thereof: muskmelon pedicel was pulverized to 40 mesh sieves;
The preparation method of described dried orange peel powder: dried orange peel was pulverized to 40 mesh sieves;
Add in pig feed per ton that this additive of 350-500 gram mixes, granulates, packing gets final product.
Beneficial effect
The compatibility of above Chinese herbal medicine is used, and can make effective enhancing pig immunity and somatotrophic pig feed additive, and this additive is comprised of natural Chinese medicinal herb, be of high nutritive value, and the compatibility science, safety, nutrition, toxic and side effect are little.On the one hand can strengthen the immunity of pig, reduce the pig incidence of disease, avoid use chemical synthesis additive (as antibiotic etc.), this feed addictive can also promote the growth of pig on the other hand, and marketing time, accelerate breeding cycle ahead of time, reduce feeding cost, increase raise benefit.This additive is conducive to promote feed and the healthy and orderly development of livestock, and human health is had to positive effect, belongs to the feed addictive of safe green.The advantages such as the astragalus polyose extracting method that the present invention improves in addition is convenient, fast, efficient, can greatly improve the purity of astragalus polyose; Compoiste fermented Chinese herbal medicine can effectively improve the active component of Chinese herbal medicine, improves the value of Chinese herbal medicine.
Concrete enforcement
Below further describe the present invention by specific embodiment.
Embodiment 1
The pig feed additive of a kind of effective enhancing pig immunity and promotion growth, every 100 parts are added following additives by following weight proportion: 10 parts of astragalus polyoses, 8 parts, wilsonii powder, 7 parts, fermentation of Chinese herbal medicine powder, 4 parts, muskmelon pedicel powder, 5 parts, dried orange peel powder, all the other are carrier.The mixture that carrier is wheat bran and defatted rice bran, 1:1 mixes in mass ratio.
The preparation method of described astragalus polyose:
Step 1: by Radix Astragali drying and crushing, cross 40 mesh sieves, by solid-liquid ratio, 1:25 adds deionized water, adds the cellulase of 0.15 %, stirs after 20 minutes ultrasonic extraction 30 minutes, ultrasonic power 90W, 40 ℃ of temperature; Vacuum filtration, get filtrate, in filtrate, adds absolute ethyl alcohol, and making concentration of alcohol is 80%, 15 ℃ of precipitation 1.5h, taking precipitate.
Step 2: sediment and deionized water are pressed to the 1:4 wiring solution-forming, by liquid-solid ratio 5:1, add active carbon and diatomite to be decoloured 20 minutes, filter and remove active carbon and diatomite, Vacuum Concentration is to 1/6 of original volume; Wherein active carbon and diatomite are pressed the 1:1 mixing;
Step 3: the extract of processing through decolouring in step 2 is joined in the chromatographic column that macroreticular resin is housed, standing 1h, the ethanol elution with 26%, collect eluent, concentrated, and spray-drying is pulverized, and crosses 60 mesh sieves, obtains astragalus polyose; Wherein macroreticular resin is AB-8.
The preparation method of described wilsonii powder: put into-75 ℃ of freezing 12h after wilsonii is cleaned, take out and put into-50 ℃ of lower freeze dryings; After drying is complete, wilsonii is carried out to coarse crushing, after allowing, adopt again superfine communication technique be pulverized, obtain the wilsonii powder.
Described composite Chinese herbal fermentate preparation method: by selected dry Radix Codonopsis, Radix Glycyrrhizae and root of kudzu vine chopping, with 75% the ethanol even sterilization of spraying, through 70 ℃ of oven dry, pulverized 40 mesh sieves, obtain mix powder, add 8 times of weight water in mix powder and control temperature to 55 ℃, add 0.2% mixed enzyme, mixed enzyme is pectase and cellulase, enzymolysis 2h, after enzymolysis toward adding the glucose of weight 0.5% in mixture, 0.1% magnesium sulfate, 0.5% sodium sulphate and 0.2% beef extract, add CICC10063 bacillus subtilis and lactobacillus bulgaricus seed liquor in fermentation medium.CICC10063 bacillus subtilis inoculum concentration is 3%, and the lactobacillus bulgaricus inoculum concentration is 5%, 35 ℃ of temperature, fermentation 40h; Then adopt the vacuum drying mode to carry out drying; Crushed after being dried is crossed 40 mesh sieves;
The mass ratio of described dry Radix Codonopsis, Radix Glycyrrhizae and the root of kudzu vine is 1:4:5;
The mass ratio of described pectase and cellulase is 1:3;
Described muskmelon pedicel powder, preparation method thereof: muskmelon pedicel was pulverized to 40 mesh sieves;
The preparation method of described dried orange peel powder: dried orange peel was pulverized to 40 mesh sieves;
Add in pig feed per ton that this additive of 400 grams mixes, granulates, packing gets final product.
Embodiment 2
The pig feed additive of a kind of effective enhancing pig immunity and promotion growth, every 100 parts are added following additives by following weight proportion: 8 parts of astragalus polyoses, 6 parts, wilsonii powder, 6 parts, fermentation of Chinese herbal medicine powder, 3 parts, muskmelon pedicel powder, 4 parts, dried orange peel powder, all the other are carrier.The mixture that carrier is wheat bran and defatted rice bran, 1:1 mixes in mass ratio.
The preparation method of described astragalus polyose:
Step 1: by Radix Astragali drying and crushing, cross 40 mesh sieves, by solid-liquid ratio, 1:20 adds deionized water, adds 0.1% cellulase, stirs after 10 minutes ultrasonic extraction 20 minutes, ultrasonic power 80W, 30 ℃ of temperature; Vacuum filtration, get filtrate, in filtrate, adds absolute ethyl alcohol, and making concentration of alcohol is 65%, 10 ℃ of precipitation 1h, taking precipitate;
Step 2: sediment and deionized water are pressed to the 1:3 wiring solution-forming, by liquid-solid ratio 5:1, add active carbon and diatomite to be decoloured 15 minutes, filter and remove active carbon and diatomite, Vacuum Concentration is to 1/5 of original volume; Wherein active carbon and diatomite are pressed the 1:1 mixing;
Step 3: the extract of processing through decolouring in step 2 is joined in the chromatographic column that macroreticular resin is housed, standing 1h, the ethanol elution with 26%, collect eluent, concentrated, and spray-drying is pulverized, and crosses 60 mesh sieves, obtains astragalus polyose; Wherein macroreticular resin is AB-8.
The preparation method of described wilsonii powder: put into-60 ℃ of freezing 12h after wilsonii is cleaned, take out and put into-40 ℃ of lower freeze dryings; After drying is complete, wilsonii is carried out to coarse crushing, after allowing, adopt again superfine communication technique be pulverized, obtain the wilsonii powder.
Described composite Chinese herbal fermentate preparation method: by selected dry Radix Codonopsis, Radix Glycyrrhizae and root of kudzu vine chopping, with 75% the ethanol even sterilization of spraying, through 60 ℃ of oven dry, pulverized 40 mesh sieves, obtain mix powder, add 8 times of weight water in mix powder and control temperature to 55 ℃, add 0.1% mixed enzyme, mixed enzyme is pectase and cellulase, enzymolysis 2h, after enzymolysis toward adding the glucose of weight 0.5% in mixture, 0.1% magnesium sulfate, 0.5% sodium sulphate and 0.2% beef extract, add CICC10063 bacillus subtilis and lactobacillus bulgaricus seed liquor in fermentation medium.CICC10063 bacillus subtilis inoculum concentration is 2%, and the lactobacillus bulgaricus inoculum concentration is 4%, 30 ℃ of temperature, fermentation 24h; Then adopt the vacuum drying mode to carry out drying, crushed after being dried is crossed 40 mesh sieves;
The mass ratio of described dry Radix Codonopsis, Radix Glycyrrhizae and the root of kudzu vine is 1:3:4;
The mass ratio of described pectase and cellulase is 1:2;
Described muskmelon pedicel powder, preparation method thereof: muskmelon pedicel was pulverized to 40 mesh sieves;
The preparation method of described dried orange peel powder: dried orange peel was pulverized to 40 mesh sieves;
Add in pig feed per ton that this additive of 350 grams mixes, granulates, packing gets final product.
Embodiment 3
The pig feed additive of a kind of effective enhancing pig immunity and promotion growth, every 100 parts are added following additives by following weight proportion: 12 parts of astragalus polyoses, 10 parts, wilsonii powder, 8 parts, fermentation of Chinese herbal medicine powder, 5 parts, muskmelon pedicel powder, 5 parts, dried orange peel powder, all the other are carrier.The mixture that carrier is wheat bran and defatted rice bran, 1:1 mixes in mass ratio.
The preparation method of described astragalus polyose:
Step 1: by Radix Astragali drying and crushing, cross 40 mesh sieves, by solid-liquid ratio, 1:30 adds deionized water, adds 0.2% cellulase, stirs after 20 minutes ultrasonic extraction 30 minutes, ultrasonic power 100W, temperature 45 C; Vacuum filtration, get filtrate, in filtrate, adds absolute ethyl alcohol, and making concentration of alcohol is 85%, 15 ℃ of precipitation 2h, taking precipitate;
Step 2: sediment and deionized water are pressed to the 1:4 wiring solution-forming, by liquid-solid ratio 5:1, add active carbon and diatomite to be decoloured 20 minutes, filter and remove active carbon and diatomite, Vacuum Concentration is to 1/6 of original volume; Wherein active carbon and diatomite are pressed the 1:1 mixing;
Step 3: the extract of processing through decolouring in step 2 is joined in the chromatographic column that macroreticular resin is housed, standing 1h, the ethanol elution with 26%, collect eluent, concentrated, and spray-drying is pulverized, and crosses 60 mesh sieves, obtains astragalus polyose; Wherein macroreticular resin is AB-8.
The preparation method of described wilsonii powder: put into-80 ℃ of freezing 12h after wilsonii is cleaned, take out and put into-55 ℃ of lower freeze dryings; After drying is complete, wilsonii is carried out to coarse crushing, after allowing, adopt again superfine communication technique be pulverized, obtain the wilsonii powder.
Described composite Chinese herbal fermentate preparation method: by selected dry Radix Codonopsis, Radix Glycyrrhizae and root of kudzu vine chopping, with 75% the ethanol even sterilization of spraying, through 80 ℃ of oven dry, pulverized 40 mesh sieves, obtain mix powder, add 8 times of weight water in mix powder and control temperature to 55 ℃, add mixed enzyme, mixed enzyme is pectase and cellulase, enzymolysis 2h, after enzymolysis toward adding the glucose of weight 0.5% in mixture, 0.1% magnesium sulfate, 0.5% sodium sulphate and 0.2% beef extract, add CICC10063 bacillus subtilis and lactobacillus bulgaricus seed liquor in fermentation medium.CICC10063 bacillus subtilis inoculum concentration is 3%, and the lactobacillus bulgaricus inoculum concentration is 5%, 35 ℃ of temperature, fermentation 48h; Then adopt the vacuum drying mode to carry out drying, crushed after being dried is crossed 40 mesh sieves
The mass ratio of described dry Radix Codonopsis, Radix Glycyrrhizae and the root of kudzu vine is 1:5:5;
The mass ratio of described pectase and cellulase is 1:3;
Described muskmelon pedicel powder, preparation method thereof: muskmelon pedicel was pulverized to 40 mesh sieves;
The preparation method of described dried orange peel powder: dried orange peel was pulverized to 40 mesh sieves;
Add in pig feed per ton that this additive of 500 grams mixes, granulates, packing gets final product.
Embodiment 4
The pig feed additive of a kind of effective enhancing pig immunity and promotion growth, every 100 parts are added following additives by following weight proportion: 10 parts of astragalus polyoses, 8 parts, wilsonii powder, 7 parts, fermentation of Chinese herbal medicine powder, 4 parts, muskmelon pedicel powder, 5 parts, dried orange peel powder, all the other are carrier.The mixture that carrier is wheat bran and defatted rice bran, 1:1 mixes in mass ratio.
The preparation method of described astragalus polyose:
Step 1: by Radix Astragali drying and crushing, cross 40 mesh sieves, by solid-liquid ratio, 1:10 adds deionized water, adds 0.05% cellulase, stirs after 5 minutes ultrasonic extraction 10 minutes, ultrasonic power 50W, 25 ℃ of temperature; Vacuum filtration, get filtrate, in filtrate, adds absolute ethyl alcohol, and making concentration of alcohol is 40%, 8 ℃ of precipitation 0.5h, gets precipitated liquid;
Step 2: sediment and deionized water are pressed to the 1:3 wiring solution-forming, by liquid-solid ratio 10:1, add active carbon and diatomite to be decoloured 10 minutes, filter and remove active carbon and diatomite, Vacuum Concentration is to 1/5 of original volume; Wherein active carbon and diatomite are pressed the 1:1 mixing;
Step 3: the extract of processing through decolouring in step 2 is joined in the chromatographic column that macroreticular resin is housed, standing 1h, the ethanol elution with 26%, collect eluent, concentrated, and spray-drying is pulverized, and crosses 60 mesh sieves, obtains astragalus polyose; Wherein macroreticular resin is AB-8.
The preparation method of described wilsonii powder: put into-40 ℃ of freezing 12h after wilsonii is cleaned, take out and put into-30 ℃ of lower freeze dryings; After drying is complete, wilsonii is carried out to coarse crushing, after allowing, adopt again superfine communication technique be pulverized, obtain the wilsonii powder.
Described composite Chinese herbal fermentate preparation method: by selected dry Radix Codonopsis, Radix Glycyrrhizae and root of kudzu vine chopping, with 75% the ethanol even sterilization of spraying, through 40 ℃ of oven dry, pulverized 40 mesh sieves, obtain mix powder, add 8 times of weight water in mix powder and control temperature to 55 ℃, add 0.08% mixed enzyme, mixed enzyme is pectase and cellulase, enzymolysis 2h, after enzymolysis toward adding the glucose of weight 0.5% in mixture, 0.1% magnesium sulfate, 0.5% sodium sulphate and 0.2% beef extract, add CICC10063 bacillus subtilis and lactobacillus bulgaricus seed liquor in fermentation medium.CICC10063 bacillus subtilis inoculum concentration is 1%, and the lactobacillus bulgaricus inoculum concentration is 1%, 25 ℃ of temperature, fermentation 18h; Then adopt the vacuum drying mode to carry out drying, crushed after being dried is crossed 40 mesh sieves
The mass ratio of described dry Radix Codonopsis, Radix Glycyrrhizae and the root of kudzu vine is 1:2:3;
The mass ratio of described pectase and cellulase is 1:1;
Described muskmelon pedicel powder, preparation method thereof: muskmelon pedicel was pulverized to 40 mesh sieves;
The preparation method of described dried orange peel powder: dried orange peel was pulverized to 40 mesh sieves;
Add in pig feed per ton that this additive of 400 grams mixes, granulates, packing gets final product.
Test example:
1, experimental animal and experimental design
300 of Guangnan (Zhanjiang) health pig that subordinate plant of rich feed corporation,Ltd average weight is 45.3 ± 2.3kg are selected in test, and statistical analysis body weight difference is not remarkable.Be divided at random 5 groups, every group of 6 repetitions, each repeats 10 male and females half and half, comprising 1 blank group and 4 test group.Do not add the additive of any enhancing pig immunity made in embodiment 1-4 in blank group swine rations, add respectively the additive that embodiment 1-4 makes in all the other 4 test group swine rationses, live pig free choice feeding and drinking-water, carry out routinely immunity and expelling parasite, observe and record the mental status of swine flu situation and pig in experimental period every day.Totally 30 days experimental period.During off-test, weigh, and ramming material.Record the swine flu incidence.Calculate each processed group daily gain, feed intake, feedstuff-meat ratio (feed intake/weightening finish) and the incidence of disease.
Data statistic analysis
Test data adopts the SSPS19.0 statistical software to carry out statistical analysis, the results are shown in following table:
Project | Control group | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 |
All the time (kg) | 44.5 | 46.1 | 45.5 | 44.9 | 45.7 |
Not heavy (kg) | 66.9 | 72.5 | 70.3 | 70.2 | 69.4 |
Daily gain (g/d head) | 756 | 881 | 828 | 845 | 791 |
Daily ingestion amount (g/d head) | 1897 | 1955 | 1945 | 1909 | 1898 |
Feedstuff-meat ratio | 2.51 | 2.22 | 2.35 | 2.26 | 2.4 |
The incidence of disease | 34.3% | 1.5% | 2.1% | 1.9% | 15.2% |
Feed intake (ADFI): the feeding capacity of each hurdle test pig of accurate recording and clout amount, calculate every pig average daily ingestion amount and average daily ingestion amount of full phase weekly;
Daily gain (ADG): test pig starts weekly and finish morning 7:30 weighs on an empty stomach, calculates average daily gain and the full phase average daily gain weekly of every pig;
Feedstuff-meat ratio (F/G): calculate according to feed intake and weightening finish.
Disease symptom: sick pig suddenly heating reaches 42 ℃ even higher, and ight soil is dry and hard, lassitude, anorexia or do not eat, and normal accumbency together, is reluctant activity, expiratory dyspnea, cough, eye, nose stream mucus.
Conclusion: result of the test shows, the feed addictive basal feed that the present invention makes is compared, and has significantly reduced the incidence of disease of pig, has strengthened the immunity of pig, has promoted the speed of growth of pig simultaneously, and the daily gain of pig is compared and is greatly improved with basestocks.
This products material is the green safety material, and can significantly reduce the incidence of disease of pig, strengthen the immunity of pig, promote the growth rate of pig, can be used as antibiotic substitute adds in pig feed, the production disease resisting effect is good, effectively promotes the mixed feed of pig growth simultaneously, has good using value and wide market prospects.
Claims (5)
1. one kind effectively strengthens immunity and promotes the pig feed additive of growing, it is characterized in that it is filled a prescription every 100 parts comprises following proportioning: astragalus polyose 8-12 part, wilsonii powder 6-10 part, fermentation of Chinese herbal medicine powder 6-8 part, muskmelon pedicel powder 3-5 part, dried orange peel powder 4-5 part, all the other are carrier, the mixture that carrier is wheat bran and defatted rice bran, 1:1 mixes in mass ratio.
2. astragalus polyose according to claim 1 is characterized in that its preparation method comprises the following steps:
Step 1: by Radix Astragali drying and crushing, cross 40 mesh sieves, by solid-liquid ratio 1:(20-30) add deionized water, add the cellulase of 0.1%-0.2%, stir ultrasonic extraction 20-30 minute after 10-20 minute, ultrasonic power 80-100W, temperature 30-45 ℃; Vacuum filtration, get filtrate, in filtrate, adds absolute ethyl alcohol, and making concentration of alcohol is 65-85%, and 10-15 ℃ of precipitation 1-2h, get precipitated liquid;
Step 2: sediment and deionized water are pressed to 1:(3-4) wiring solution-forming, add active carbon and the diatomite 15-20 minute that decoloured by liquid-solid ratio 5:1, filters and remove active carbon and diatomite, and Vacuum Concentration is to the 1/5-1/6 of original volume; Wherein active carbon and diatomite are pressed the 1:1 mixing;
Step 3: the extract of processing through decolouring in step 2 is joined in the chromatographic column that macroreticular resin is housed, standing 1h, the ethanol elution with 26%, collect eluent, concentrated, and spray-drying is pulverized, and crosses 60 mesh sieves, obtains astragalus polyose; Wherein macroreticular resin is AB-8.
3. wilsonii powder according to claim 1, is characterized in that its preparation method is: put into-60 ℃ to-80 ℃ of freezing 12h after wilsonii is cleaned, take out and put into-40 ℃ to-55 ℃ of lower freeze dryings; After drying is complete, wilsonii is carried out to coarse crushing, and then adopt superfine communication technique to be pulverized, obtain the wilsonii powder.
4. fermentation of Chinese herbal medicine powder according to claim 1, it is characterized in that: by selected dry Radix Codonopsis, Radix Glycyrrhizae and root of kudzu vine chopping, with 75% the ethanol even sterilization of spraying, through 60-80 ℃ of oven dry, pulverized 40 mesh sieves, obtain mix powder, add 8 times of weight water in mix powder and control temperature to 55 ℃, add the 0.1-0.3% mixed enzyme, mixed enzyme is pectase and cellulase, enzymolysis 2h, after enzymolysis toward adding the glucose of weight 0.5% in mixture, 0.1% magnesium sulfate, 0.5% sodium sulphate and 0.2% beef extract, add CICC10063 bacillus subtilis and lactobacillus bulgaricus seed liquor in fermentation medium, CICC10063 bacillus subtilis inoculum concentration is 2-3%, and the lactobacillus bulgaricus inoculum concentration is 4-5%, temperature 30-35 ℃, fermentation 24-48h, then adopt the vacuum drying mode to carry out drying, crushed after being dried is crossed 40 mesh sieves,
The mass ratio of described dry Radix Codonopsis, Radix Glycyrrhizae and the root of kudzu vine is 1:(3-5): (4-5);
The mass ratio of described pectase and cellulase is 1:(2-3).
5. according to the pig feed additive of the described a kind of effective enhancing pig immunity of claim 1 and promotion growth, the addition in pig feed is the 350-500g/ ton.
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CN109350655B (en) * | 2018-11-30 | 2021-06-22 | 河北征宇制药有限公司 | Fermented traditional Chinese medicine for improving growth and reproductive performance of pigs and preparation method thereof |
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Effective date of registration: 20170216 Address after: 436043 Ezhou Economic Development Zone, Wuhan Port Industrial Park, Hubei Patentee after: Ezhou twin Feed Co., Ltd. Address before: 524045 Guangdong Province, Zhanjiang city Chikan North Road No. 2 Patentee before: Guangnan (Zhanjiang) Jiafeng Feed Co.,Ltd. |