CN103947907B - Pig immune-enhanced feed additive capable of replacing antibiotic - Google Patents

Pig immune-enhanced feed additive capable of replacing antibiotic Download PDF

Info

Publication number
CN103947907B
CN103947907B CN201410213400.0A CN201410213400A CN103947907B CN 103947907 B CN103947907 B CN 103947907B CN 201410213400 A CN201410213400 A CN 201410213400A CN 103947907 B CN103947907 B CN 103947907B
Authority
CN
China
Prior art keywords
powder
fructus choerospondiatis
lotus leaf
mass ratio
mesh sieves
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201410213400.0A
Other languages
Chinese (zh)
Other versions
CN103947907A (en
Inventor
王勇飞
朱长生
车政权
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meizhou twin Feed Co., Ltd.
Original Assignee
TWINS (GROUP) CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TWINS (GROUP) CO Ltd filed Critical TWINS (GROUP) CO Ltd
Priority to CN201410213400.0A priority Critical patent/CN103947907B/en
Publication of CN103947907A publication Critical patent/CN103947907A/en
Application granted granted Critical
Publication of CN103947907B publication Critical patent/CN103947907B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

Landscapes

  • Medicines Containing Plant Substances (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a pig immune-enhanced feed additive capable of replacing an antibiotic. The additive comprises lotus leaf polysaccharides, fructus choerospondiatis extract, Chinese angelica powder, perilla leaf powder, purpleflower holly leaf powder, herba glechomae powder, a microecological preparation, allicin, complex vitamins, complex minerals and a carrier. Main ingredients of the additive are natural ingredients, so that the additive has the advantages of high nutritional value, scientific compatibility, safety, nutrition and low toxicity and side effects, can greatly help to enhance immunity of pigs and reduce disease incidence of the pigs, belongs to a safe and green feed additive, can replace the antibiotic to be applied in feed and further has very broad prospects.

Description

A kind of alternative antibiotic pig immunity enhancement type feed addictive
Technical field
The present invention relates to a kind of feed addictive, particularly relate to a kind of alternative antibiotic pig immunity enhancement type feed addictive, belong to feed additive field.
Background technology
Various because of additive cause food security be in the news in a large number, one the time whole society in commotion, make us greatly alarmed, bring certain de-stabilising effect to society.Along with the development of society and people's living standard, the improving constantly of know-how, pursue safety, the step of food of nutrition will constantly accelerate, also will strengthen concern dynamics to the problem close examination of additive and research.Feed addictive is the important substance prerequisite that modern feed industryization is produced, it be based on different object (as supplement must nutrient, develop immunitypty, increase search for food, growth promoting effects, raising feed efficiency, improve feed and Animal product quality etc.) and the different material that is added in mixed feed, mainly comprise chemical synthesis additive and natural additive.Current feedstuff industry is mainly based on chemical synthesis additive, and mainly comprise antibiotic, hormone, chemical synthetic drug etc., it is widely used in Immune-enhancing effect and growth promotion etc., plays to the development of feed industry and animal husbandry the effect of actively promoting.But deepening continuously along with research, it is found that the drawback that chemical synthesis additive brings the behind of tremendous economic interests under cover huge, as excessive use antibiotic can cause the quality of animal meat product and product thereof to decline and antibiotic resistance enhancing, bring serious potential safety hazard to the mankind.Some country has started explicit order restriction or has forbidden in feed, add some chemical synthesis additives, European Union is by corresponding regulation, European Union will carry out EU-25 decree in January, 2006, forbid in pig feed, add the feeding antibiotic for growth promotion object.
In recent years, because China raises pigs the transition of mode, swine rearing density increases, the genetic potential of pig improves, and the living environment of pig becomes bad, and the circulation of live hog is frequent, the factors such as a large amount of interpolation antibiosis rope and medicine cause: the immunity degradation of pig on the one hand, and the virulence of cause of disease increases with variation on the other hand.The pig industry of China faces day by day serious epidemic disease challenge, and the loss that epidemic disease causes increases day by day.
Therefore develop the feed addictive of a kind of natural, nutrition, safety, be used for strengthening pig immunity, the development of China's animal husbandry is had very important significance.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Be very effective, the pig of stable performance immunity enhancement type feed addictive, this additive effectively can strengthen the immunity of pig, reduce the incidence of disease, improve the health degree of pig, promote pig growth, the low economic loss caused of immunity during effective minimizing pig produces, increases economic benefit; Meanwhile, the use of this additive, to the use reducing antibiosis, for consumer provides the meat product of green safety to have very important help.
Technical scheme provided by the invention is as described below:
A kind of alternative antibiotic pig immunity enhancement type feed addictive is made up of lotus leaf polysaccharide, Fructus Choerospondiatis extract, angelica powder, perilla leaf powder, Chinese holly powder, Longtube Ground Ivy Herb powder, probiotics, allicin, B B-complex, composite mineral matter and carrier;
A kind of alternative antibiotic pig immunity enhancement type feed addictive, every 100 parts are made up of by weight following composition: lotus leaf polysaccharide 2-6 part, Fructus Choerospondiatis extract 2-6 part, angelica powder 1-4 part, perilla leaf powder 3-8 part, Chinese holly powder 2-8 part, Longtube Ground Ivy Herb powder 1-3 part, probiotics 3-9 part, allicin 1-4 part, B B-complex 0.4-0.8 part, composite mineral matter 0.2-0.8 part, all the other are carrier, carrier is by corn stalk powder, defatted rice bran and zeolite powder be 2:4-6:3 composition in mass ratio, corn stalk powder, defatted rice bran and zeolite powder pulverized 40 mesh sieves in advance,
The preparation method of described lotus leaf polysaccharide is: cleaned up by fresh lotus leaf, at putting into-60 to-80 DEG C, freezing 14-18h, then be placed in 50-60 DEG C of air dry oven carry out drying process, make its moisture lower than 18%, pulverized 30 mesh sieves and obtain lotus leaf powder; In lotus leaf powder, add by solid-to-liquid ratio 1:4 the ethanol that concentration is 85%, at 25 DEG C, soak 24h, filter, get filter residue; Mixed by solid-to-liquid ratio 1:20-25 with distilled water by filter residue, at 55-65 DEG C, carry out refluxing extraction, extraction time is 2-4h, extracts after terminating and carries out filtration treatment, filtrate drying and crushing is crossed 60 mesh sieves and namely obtains lotus leaf polysaccharide.
The preparation method of described Fructus Choerospondiatis extract is: 20 mesh sieves were pulverized in fructus choerospondiatis impurity elimination, obtains fructus choerospondiatis powder; By fructus choerospondiatis powder and complex enzyme in mass ratio 100:2-3 mix, add by solid-to-liquid ratio 1:6-10 the ethanol that concentration is 62-70% again in the mixture of fructus choerospondiatis powder and complex enzyme, adopt ultrasonic extraction 30-40min, ultrasonic temperature is 45-60 DEG C, and ultrasonic power is 160-200W, carries out filtration treatment after ultrasonic end, get filtrate, by filtrate drying and crushing, cross 30 mesh sieves, obtain Fructus Choerospondiatis extract; Described complex enzyme is cellulase, pectase and amylase 4:2:1 composition in mass ratio;
The preparation method of described angelica powder is: Radix Angelicae Sinensis was pulverized 60 mesh sieves;
The preparation method of described perilla leaf powder is: perilla leaf was pulverized 60 mesh sieves;
The preparation method of described Chinese holly powder is: Chinese holly was pulverized 60 mesh sieves;
The preparation method of described Longtube Ground Ivy Herb powder is: Longtube Ground Ivy Herb was pulverized 60 mesh sieves;
Described probiotics by Bacillus licheniformis powder, bacillus subtilis bacterium powder, bacillus pumilus bacterium powder and Pediococcus acidilactici bacterium powder in mass ratio 3-5:3-5:2-4:1-2 form;
Described B B-complex by vitamin A, vitamin C, vitamin K, nicotinic acid, biotin in mass ratio 4-6:2-4:1-3:3-5:2-5 form;
Described composite mineral matter by sodium hydrogen phosphate, ferrous lactate, manganese chloride, KI in mass ratio 1-2:2-4:1-3:1-3 form;
A kind of alternative antibiotic pig immunity enhancement type feed addictive in the present invention, its preparation method is:
(1) angelica powder, perilla leaf powder, Chinese holly powder, Longtube Ground Ivy Herb are pressed formula rate mixing, at being placed in 25 DEG C, temperature fries 2h, stand-by;
(2) B B-complex and defatted rice bran are mixed; Stand-by;
(3) composite mineral matter and zeolite powder are mixed; Stand-by;
(4) lotus leaf polysaccharide, Fructus Choerospondiatis extract, probiotics and allicin are mixed, stand-by;
(5) mixed with corn stalk powder by gains in (1), (2), (3), (4), obtaining can.
A kind of alternative antibiotic pig immunity enhancement type feed addictive in the present invention, the addition in pig feed is 600-1200 gram/ton.
Beneficial effect
The compatibility of above composition uses, the pig feed additive effectively strengthening pig immunity can be obtained, this additive main component is natural component, be of high nutritive value, compatibility science, safety, nutrition, toxic and side effect are little, to the immunity strengthening pig, reduce the pig incidence of disease, avoid and use chemical synthesis additive (as antibiotic etc.) to have very large help.In addition, inventor is in the favorite outer discovery of invention process, and this additive is to treating swine influenza, having an unexpected effect to the daily gain and reduction feedstuff-meat ratio tool that improve pig.This additive is conducive to promoting feed and the healthy and orderly development of livestock, has positive effect, belong to the feed addictive of safe green to human health.
Specific embodiment
Come to set forth the present invention further below by way of specific embodiment.
Embodiment 1
A kind of alternative antibiotic pig immunity enhancement type feed addictive, every 100 parts are made up of by weight following composition: lotus leaf polysaccharide 2 parts, Fructus Choerospondiatis extract 2 parts, angelica powder 1 part, 3 parts, perilla leaf powder, 2 parts, Chinese holly powder, 1 part, Longtube Ground Ivy Herb powder, probiotics 3 parts, allicin 1 part, B B-complex 0.4 part, composite mineral matter 0.2 part, all the other are carrier, carrier by corn stalk powder, defatted rice bran and zeolite powder in mass ratio 2:4:3 form, corn stalk powder, defatted rice bran and zeolite powder pulverized 40 mesh sieves in advance;
The preparation method of described lotus leaf polysaccharide is: cleaned up by fresh lotus leaf, at putting into-60 DEG C, freezing 14h, then be placed in 50 DEG C of air dry ovens carry out drying process, make its moisture lower than 18%, pulverized 30 mesh sieves and obtain lotus leaf powder; In lotus leaf powder, add by solid-to-liquid ratio 1:4 the ethanol that concentration is 85%, at 25 DEG C, soak 24h, filter, get filter residue; Mixed by solid-to-liquid ratio 1:20 with distilled water by filter residue, at 55 DEG C, carry out refluxing extraction, extraction time is 2h, extracts after terminating and carries out filtration treatment, filtrate drying and crushing is crossed 60 mesh sieves and namely obtains lotus leaf polysaccharide.
The preparation method of described Fructus Choerospondiatis extract is: 20 mesh sieves were pulverized in fructus choerospondiatis impurity elimination, obtains fructus choerospondiatis powder; By fructus choerospondiatis powder and complex enzyme in mass ratio 100:2 mix, add by solid-to-liquid ratio 1:6 the ethanol that concentration is 62% again in the mixture of fructus choerospondiatis powder and complex enzyme, adopt ultrasonic extraction 30min, ultrasonic temperature is 45 DEG C, and ultrasonic power is 160W, carries out filtration treatment after ultrasonic end, get filtrate, by filtrate drying and crushing, cross 30 mesh sieves, obtain Fructus Choerospondiatis extract; Described complex enzyme is cellulase, pectase and amylase 4:2:1 composition in mass ratio.
The preparation method of described angelica powder is: Radix Angelicae Sinensis was pulverized 60 mesh sieves;
The preparation method of described perilla leaf powder is: perilla leaf was pulverized 60 mesh sieves;
The preparation method of described Chinese holly powder is: Chinese holly was pulverized 60 mesh sieves;
The preparation method of described Longtube Ground Ivy Herb powder is: Longtube Ground Ivy Herb was pulverized 60 mesh sieves;
Described probiotics by Bacillus licheniformis powder, bacillus subtilis bacterium powder, bacillus pumilus bacterium powder and Pediococcus acidilactici bacterium powder in mass ratio 3:3:2:1 form;
Described B B-complex by vitamin A, vitamin C, vitamin K, nicotinic acid, biotin in mass ratio 4:2:1:3:2 form;
Described composite mineral matter by sodium hydrogen phosphate, ferrous lactate, manganese chloride, KI in mass ratio 1:2:1:1 form;
A kind of alternative antibiotic pig immunity enhancement type feed addictive in the present invention, its preparation method is:
(1) angelica powder, perilla leaf powder, Chinese holly powder, Longtube Ground Ivy Herb are pressed formula rate mixing, at being placed in 25 DEG C, temperature fries 2h, stand-by;
(2) B B-complex and defatted rice bran are mixed; Stand-by;
(3) composite mineral matter and zeolite powder are mixed; Stand-by;
(4) lotus leaf polysaccharide, Fructus Choerospondiatis extract, probiotics and allicin are mixed, stand-by;
(5) gains in (1), (2), (3), (4) are mixed with corn stalk powder.
A kind of alternative antibiotic pig immunity enhancement type feed addictive in the present invention, the addition in pig feed is 600 grams/ton.
Embodiment 2
A kind of alternative antibiotic pig immunity enhancement type feed addictive, every 100 parts are made up of by weight following composition: lotus leaf polysaccharide 4 parts, Fructus Choerospondiatis extract 4 parts, angelica powder 3 parts, 6 parts, perilla leaf powder, 5 parts, Chinese holly powder, 2 parts, Longtube Ground Ivy Herb powder, probiotics 6 parts, allicin 3 parts, B B-complex 0.6 part, composite mineral matter 0.5 part, all the other are carrier, carrier by corn stalk powder, defatted rice bran and zeolite powder in mass ratio 2:5:3 form, corn stalk powder, defatted rice bran and zeolite powder pulverized 40 mesh sieves in advance;
The preparation method of described lotus leaf polysaccharide is: cleaned up by fresh lotus leaf, at putting into-70 DEG C, freezing 16h, then be placed in 55 DEG C of air dry ovens carry out drying process, make its moisture lower than 18%, pulverized 30 mesh sieves and obtain lotus leaf powder; In lotus leaf powder, add by solid-to-liquid ratio 1:4 the ethanol that concentration is 85%, at 25 DEG C, soak 24h, filter, get filter residue; Mixed by solid-to-liquid ratio 1:23 with distilled water by filter residue, at 60 DEG C, carry out refluxing extraction, extraction time is 3h, extracts after terminating and carries out filtration treatment, filtrate drying and crushing is crossed 60 mesh sieves and namely obtains lotus leaf polysaccharide.
The preparation method of described Fructus Choerospondiatis extract is: 20 mesh sieves were pulverized in fructus choerospondiatis impurity elimination, obtains fructus choerospondiatis powder; By fructus choerospondiatis powder and complex enzyme in mass ratio 100:2.5 mix, add by solid-to-liquid ratio 1:8 the ethanol that concentration is 68% again in the mixture of fructus choerospondiatis powder and complex enzyme, adopt ultrasonic extraction 35min, ultrasonic temperature is 55 DEG C, and ultrasonic power is 180W, carries out filtration treatment after ultrasonic end, get filtrate, by filtrate drying and crushing, cross 30 mesh sieves, obtain Fructus Choerospondiatis extract; Described complex enzyme is cellulase, pectase and amylase 4:2:1 composition in mass ratio.
The preparation method of described angelica powder is: Radix Angelicae Sinensis was pulverized 60 mesh sieves;
The preparation method of described perilla leaf powder is: perilla leaf was pulverized 60 mesh sieves;
The preparation method of described Chinese holly powder is: Chinese holly was pulverized 60 mesh sieves;
The preparation method of described Longtube Ground Ivy Herb powder is: Longtube Ground Ivy Herb was pulverized 60 mesh sieves;
Described probiotics by Bacillus licheniformis powder, bacillus subtilis bacterium powder, bacillus pumilus bacterium powder and Pediococcus acidilactici bacterium powder in mass ratio 4:4:3:2 form;
Described B B-complex by vitamin A, vitamin C, vitamin K, nicotinic acid, biotin in mass ratio 5:3:2:4:3 form;
Described composite mineral matter by sodium hydrogen phosphate, ferrous lactate, manganese chloride, KI in mass ratio 2:3:2:2 form;
A kind of alternative antibiotic pig immunity enhancement type feed addictive in the present invention, its preparation method is with embodiment 1.
A kind of alternative antibiotic pig immunity enhancement type feed addictive in the present invention, the addition in pig feed is 850 grams/ton.
Embodiment 3
A kind of alternative antibiotic pig immunity enhancement type feed addictive, every 100 parts are made up of by weight following composition: lotus leaf polysaccharide 6 parts, Fructus Choerospondiatis extract 6 parts, angelica powder 4 parts, 8 parts, perilla leaf powder, 8 parts, Chinese holly powder, 3 parts, Longtube Ground Ivy Herb powder, probiotics 9 parts, allicin 4 parts, B B-complex 0.8 part, composite mineral matter 0.8 part, all the other are carrier, carrier by corn stalk powder, defatted rice bran and zeolite powder in mass ratio 2:6:3 form, corn stalk powder, defatted rice bran and zeolite powder pulverized 40 mesh sieves in advance;
The preparation method of described lotus leaf polysaccharide is: cleaned up by fresh lotus leaf, at putting into-80 DEG C, freezing 18h, then be placed in 60 DEG C of air dry ovens carry out drying process, make its moisture lower than 18%, pulverized 30 mesh sieves and obtain lotus leaf powder; In lotus leaf powder, add by solid-to-liquid ratio 1:4 the ethanol that concentration is 85%, at 25 DEG C, soak 24h, filter, get filter residue; Mixed by solid-to-liquid ratio 1:25 with distilled water by filter residue, at 65 DEG C, carry out refluxing extraction, extraction time is 4h, extracts after terminating and carries out filtration treatment, filtrate drying and crushing is crossed 60 mesh sieves and namely obtains lotus leaf polysaccharide.
The preparation method of described Fructus Choerospondiatis extract is: 20 mesh sieves were pulverized in fructus choerospondiatis impurity elimination, obtains fructus choerospondiatis powder; By fructus choerospondiatis powder and complex enzyme in mass ratio 100:3 mix, add by solid-to-liquid ratio 1:10 the ethanol that concentration is 70% again in the mixture of fructus choerospondiatis powder and complex enzyme, adopt ultrasonic extraction 40min, ultrasonic temperature is 60 DEG C, and ultrasonic power is 200W, carries out filtration treatment after ultrasonic end, get filtrate, by filtrate drying and crushing, cross 30 mesh sieves, obtain Fructus Choerospondiatis extract; Described complex enzyme is cellulase, pectase and amylase 4:2:1 composition in mass ratio.
The preparation method of described angelica powder is: Radix Angelicae Sinensis was pulverized 60 mesh sieves;
The preparation method of described perilla leaf powder is: perilla leaf was pulverized 60 mesh sieves;
The preparation method of described Chinese holly powder is: Chinese holly was pulverized 60 mesh sieves;
The preparation method of described Longtube Ground Ivy Herb powder is: Longtube Ground Ivy Herb was pulverized 60 mesh sieves;
Described probiotics by Bacillus licheniformis powder, bacillus subtilis bacterium powder, bacillus pumilus bacterium powder and Pediococcus acidilactici bacterium powder in mass ratio 5:5:4:2 form;
Described B B-complex by vitamin A, vitamin C, vitamin K, nicotinic acid, biotin in mass ratio 6:4:3:5:5 form;
Described composite mineral matter by sodium hydrogen phosphate, ferrous lactate, manganese chloride, KI in mass ratio 2:4:3:3 form;
A kind of alternative antibiotic pig immunity enhancement type feed addictive in the present invention, its preparation method is with embodiment 1.
A kind of alternative antibiotic pig immunity enhancement type feed addictive in the present invention, the addition in pig feed is 1200 grams/ton.
Embodiment 4
A kind of alternative antibiotic pig immunity enhancement type feed addictive, every 100 parts are made up of by weight following composition: lotus leaf polysaccharide 1 part, Fructus Choerospondiatis extract 1 part, angelica powder 6 parts, 1 part, perilla leaf powder, 1 part, Chinese holly powder, 7 parts, Longtube Ground Ivy Herb powder, probiotics 1 part, allicin 1 part, B B-complex 0.2 part, composite mineral matter 0.1 part, all the other are carrier, carrier by corn stalk powder, defatted rice bran and zeolite powder in mass ratio 1:1:1 form, corn stalk powder, defatted rice bran and zeolite powder pulverized 40 mesh sieves in advance;
All the other are with embodiment 2.
Test example 1
Subordinate plant of test selection twins (group) limited company average weight is the health pig 300 of 47.3kg, and statistical analysis weight differences is not remarkable.Be divided into 5 groups at random, often organize 6 repetitions, each repetition 10, male and female half and half, comprising 1 blank group and 4 test group.Daily ration based on blank group swine rations, the additive that embodiment 1-4 is obtained is added respectively in all the other 4 test group swine rationses, live pig free choice feeding and drinking-water, carry out immunity and expelling parasite routinely, and in experimental period, every day observes and records the mental status of swine flu situation and pig.Totally 30 days experimental period.Weigh during off-test, and ramming material.Record swine flu incidence.Calculate each processed group daily gain, feedstuff-meat ratio (feed intake/weightening finish) and the incidence of disease.
Result of the test shows, the feed addictive basal feed that the present invention obtains is compared, and significantly can reduce the incidence of disease of pig, enhance the immunity of pig, simultaneously to the speed of growth facilitating pig, improve pig daily gain with and reduce feedstuff-meat ratio also tool be very helpful.
Experimental example 2
Select and suffer from grippal pig 30, continuous 3-5 days feeds the feed of additive prepared containing embodiment 2, and pig rehabilitation rate reaches more than 90%.

Claims (5)

1. an alternative antibiotic pig immunity enhancement type feed addictive, it is characterized in that every 100 parts are made up of by weight following composition: lotus leaf polysaccharide 2-6 part, Fructus Choerospondiatis extract 2-6 part, angelica powder 1-4 part, perilla leaf powder 3-8 part, Chinese holly powder 2-8 part, Longtube Ground Ivy Herb powder 1-3 part, probiotics 3-9 part, allicin 1-4 part, B B-complex 0.4-0.8 part, composite mineral matter 0.2-0.8 part, all the other are carrier, carrier is by corn stalk powder, defatted rice bran and zeolite powder be 2:4-6:3 composition in mass ratio, corn stalk powder, defatted rice bran and zeolite powder pulverized 40 mesh sieves in advance,
The preparation method of described lotus leaf polysaccharide is: cleaned up by fresh lotus leaf, at putting into-60 to-80 DEG C, freezing 14-18h, then be placed in 50-60 DEG C of air dry oven carry out drying process, make its moisture lower than 18%, pulverized 30 mesh sieves and obtain lotus leaf powder; In lotus leaf powder, add by solid-to-liquid ratio 1:4 the ethanol that concentration is 85%, at 25 DEG C, soak 24h, filter, get filter residue; Mixed by solid-to-liquid ratio 1:20-25 with distilled water by filter residue, at 55-65 DEG C, carry out refluxing extraction, extraction time is 2-4h, extracts after terminating and carries out filtration treatment, filtrate drying and crushing is crossed 60 mesh sieves and namely obtains lotus leaf polysaccharide;
The preparation method of described Fructus Choerospondiatis extract is: 20 mesh sieves were pulverized in fructus choerospondiatis impurity elimination, obtains fructus choerospondiatis powder; By fructus choerospondiatis powder and complex enzyme in mass ratio 100:2-3 mix, add by solid-to-liquid ratio 1:6-10 the ethanol that concentration is 62-70% again in the mixture of fructus choerospondiatis powder and complex enzyme, adopt ultrasonic extraction 30-40min, ultrasonic temperature is 45-60 DEG C, and ultrasonic power is 160-200W, carries out filtration treatment after ultrasonic end, get filtrate, by filtrate drying and crushing, cross 30 mesh sieves, obtain Fructus Choerospondiatis extract; Described complex enzyme is cellulase, pectase and amylase 4:2:1 composition in mass ratio;
Described probiotics by Bacillus licheniformis powder, bacillus subtilis bacterium powder, bacillus pumilus bacterium powder and Pediococcus acidilactici bacterium powder in mass ratio 3-5:3-5:2-4:1-2 form;
Described B B-complex by vitamin A, vitamin C, vitamin K, nicotinic acid, biotin in mass ratio 4-6:2-4:1-3:3-5:2-5 form;
Described composite mineral matter by sodium hydrogen phosphate, ferrous lactate, manganese chloride, KI in mass ratio 1-2:2-4:1-3:1-3 form.
2. a kind of alternative antibiotic pig immunity enhancement type feed addictive according to claim 1, it is characterized in that every 100 parts are made up of by weight following composition: lotus leaf polysaccharide 4 parts, Fructus Choerospondiatis extract 4 parts, angelica powder 3 parts, 6 parts, perilla leaf powder, 5 parts, Chinese holly powder, 2 parts, Longtube Ground Ivy Herb powder, probiotics 6 parts, allicin 3 parts, B B-complex 0.6 part, composite mineral matter 0.5 part, all the other are carrier, carrier is by corn stalk powder, defatted rice bran and zeolite powder be 2:5:3 composition in mass ratio, corn stalk powder, defatted rice bran and zeolite powder pulverized 40 mesh sieves in advance,
The preparation method of described lotus leaf polysaccharide is: cleaned up by fresh lotus leaf, at putting into-70 DEG C, freezing 16h, then be placed in 55 DEG C of air dry ovens carry out drying process, make its moisture lower than 18%, pulverized 30 mesh sieves and obtain lotus leaf powder; In lotus leaf powder, add by solid-to-liquid ratio 1:4 the ethanol that concentration is 85%, at 25 DEG C, soak 24h, filter, get filter residue; Mixed by solid-to-liquid ratio 1:23 with distilled water by filter residue, at 60 DEG C, carry out refluxing extraction, extraction time is 3h, extracts after terminating and carries out filtration treatment, filtrate drying and crushing is crossed 60 mesh sieves and namely obtains lotus leaf polysaccharide;
The preparation method of described Fructus Choerospondiatis extract is: 20 mesh sieves were pulverized in fructus choerospondiatis impurity elimination, obtains fructus choerospondiatis powder; By fructus choerospondiatis powder and complex enzyme in mass ratio 100:2.5 mix, add by solid-to-liquid ratio 1:8 the ethanol that concentration is 68% again in the mixture of fructus choerospondiatis powder and complex enzyme, adopt ultrasonic extraction 35min, ultrasonic temperature is 55 DEG C, and ultrasonic power is 180W, carries out filtration treatment after ultrasonic end, get filtrate, by filtrate drying and crushing, cross 30 mesh sieves, obtain Fructus Choerospondiatis extract; Described complex enzyme is cellulase, pectase and amylase 4:2:1 composition in mass ratio;
Described probiotics by Bacillus licheniformis powder, bacillus subtilis bacterium powder, bacillus pumilus bacterium powder and Pediococcus acidilactici bacterium powder in mass ratio 4:4:3:2 form;
Described B B-complex by vitamin A, vitamin C, vitamin K, nicotinic acid, biotin in mass ratio 5:3:2:4:3 form;
Described composite mineral matter by sodium hydrogen phosphate, ferrous lactate, manganese chloride, KI in mass ratio 2:3:2:2 form.
3., according to the alternative antibiotic pig immunity enhancement type feed addictive of the arbitrary described one of claim 1-2, it is characterized in that preparation method is:
(1) angelica powder, perilla leaf powder, Chinese holly powder, Longtube Ground Ivy Herb are pressed formula rate mixing, at being placed in 25 DEG C, temperature fries 2h, stand-by;
(2) B B-complex and defatted rice bran are mixed; Stand-by;
(3) composite mineral matter and zeolite powder are mixed; Stand-by;
(4) lotus leaf polysaccharide, Fructus Choerospondiatis extract, probiotics and allicin are mixed, stand-by;
(5) mixed with corn stalk powder by gains in (1), (2), (3), (4), obtaining can.
4. a kind of alternative antibiotic pig immunity enhancement type feed addictive according to claim 1 or 2, is characterized in that the addition in pig feed is 600-1200 gram/ton.
5. a kind of alternative antibiotic pig immunity enhancement type feed addictive according to claim 4, is characterized in that the addition in pig feed is 850 grams/ton.
CN201410213400.0A 2014-05-21 2014-05-21 Pig immune-enhanced feed additive capable of replacing antibiotic Active CN103947907B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410213400.0A CN103947907B (en) 2014-05-21 2014-05-21 Pig immune-enhanced feed additive capable of replacing antibiotic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410213400.0A CN103947907B (en) 2014-05-21 2014-05-21 Pig immune-enhanced feed additive capable of replacing antibiotic

Publications (2)

Publication Number Publication Date
CN103947907A CN103947907A (en) 2014-07-30
CN103947907B true CN103947907B (en) 2015-03-04

Family

ID=51325378

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410213400.0A Active CN103947907B (en) 2014-05-21 2014-05-21 Pig immune-enhanced feed additive capable of replacing antibiotic

Country Status (1)

Country Link
CN (1) CN103947907B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104304728B (en) * 2014-09-24 2017-05-17 江西双胞胎实业有限公司 Pig feed additive for improving intestinal tract health and promoting growth
CN104286540A (en) * 2014-10-09 2015-01-21 胡兰春 Biological feed additive with function of improving intestinal health of pigs
CN104273395A (en) * 2014-10-28 2015-01-14 广东双胞胎饲料有限公司 Pig biological feed additive capable of effectively enhancing immunity
CN104397426A (en) * 2014-12-05 2015-03-11 乐山双胞胎饲料有限公司 Pig feed additive capable of promoting growth and improving feed nutrient utilization rate
CN104489408A (en) * 2014-12-30 2015-04-08 瑞金双胞胎饲料有限公司 Porcine feed additive for effectively improving intestinal health and enhancing immunity
CN105325724A (en) * 2015-11-03 2016-02-17 深圳市澳华农牧有限公司 Compound fodder additive for pigs and preparing method and application thereof
CN105309809A (en) * 2015-11-30 2016-02-10 大理双胞胎饲料有限公司 Novel green feed additive for pigs
CN105533205A (en) * 2015-12-30 2016-05-04 云南双胞胎饲料有限公司 Compound green feed additive for pigs
CN106107120A (en) * 2016-06-30 2016-11-16 玉溪双胞胎饲料有限公司 A kind of biology feed additive of enhancing immunity
CN106360007A (en) * 2016-09-22 2017-02-01 广西大学 Traditional Chinese medicine pig feed additive capable of replacing antibiotics and preparation method thereof
CN106417920A (en) * 2016-09-22 2017-02-22 广西大学 Traditional Chinese medicine feed additive capable of replacing antibiotics and preparation method thereof
CN106234805A (en) * 2016-09-30 2016-12-21 安徽华澳生物技术有限公司 A kind of feed additive preventing and treating in-pig chlamydiosis
CN108887231A (en) * 2018-06-11 2018-11-27 泸水市林森畜牧科技发展有限公司 A kind of cultural method of breeder de- warm phase
CN109329620A (en) * 2018-10-08 2019-02-15 安徽省江北淝河养殖有限公司 A kind of nutritional additive fed for live pig

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103549159A (en) * 2013-11-22 2014-02-05 青岛农业大学 Poultry feed additive
CN103598408A (en) * 2013-10-16 2014-02-26 当涂县湖阳兴旺园养猪场 Pig forage for increasing lean meat rate

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103598408A (en) * 2013-10-16 2014-02-26 当涂县湖阳兴旺园养猪场 Pig forage for increasing lean meat rate
CN103549159A (en) * 2013-11-22 2014-02-05 青岛农业大学 Poultry feed additive

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
周丽波,等.3种广枣提取物对哇巴因诱发豚鼠心律失常作用的比较..《中国民族医药杂志》.2008,(第1期),34-36. *
王在贵,等.可溶性荷叶多糖的提取与初步纯化..《中国饲料》.2008,(第19期),39-41. *

Also Published As

Publication number Publication date
CN103947907A (en) 2014-07-30

Similar Documents

Publication Publication Date Title
CN103947907B (en) Pig immune-enhanced feed additive capable of replacing antibiotic
CN103734543B (en) Biological feed additive capable of improving meat quality and promoting growth for fattening pigs
CN104171434B (en) The pig biology feed additive of develop immunitypty and raising efficiency of feed utilization
CN103549217B (en) Safe and efficient biological feed additive for pigs
CN103750072B (en) Green pig feed additive capable of substituting antibiotic
CN103416629B (en) Pig feed additive capable of effectively improving pig immunity and promoting pig growth
CN104116009A (en) Feed additive capable of effectively promoting digestive absorption and improving immunity
CN103892053B (en) Pig growth promotion type green feed additive capable of replacing antibiotics
CN103250879B (en) Compound feed for adjusting intestinal development of piglets, and application thereof
CN104273395A (en) Pig biological feed additive capable of effectively enhancing immunity
CN103392946A (en) Pig feed additive capable of effectively improving immunity and intestinal health
CN104146182A (en) Biological feed additive for preventing and treating diarrhoea of piggies
CN104431337A (en) Pig feed additive promoting growth and improving immunity
CN104397426A (en) Pig feed additive capable of promoting growth and improving feed nutrient utilization rate
CN103947906B (en) Pig microecological preparation and preparation method thereof
CN103652492A (en) Lactating sow feed additive capable of improving lactation yield and boosting immunity
CN105309809A (en) Novel green feed additive for pigs
CN104304728A (en) Pig feed additive for improving intestinal tract health and promoting growth
CN104171593B (en) A kind of farrowing sow feed additive special
CN104489408A (en) Porcine feed additive for effectively improving intestinal health and enhancing immunity
CN103750071B (en) Green feed additive for pigs for increasing lean meat percentage
CN105166487A (en) Composite Chinese herbal medicine feed additive for pigs and preparation method of composite Chinese herbal medicine feed additive
CN104543376A (en) Chinese herbal medicine composite additive for effectively improving intestinal health and pork quality
CN109349439A (en) The preparation method and application of pig folium cortex eucommiae fermented feed
CN104286540A (en) Biological feed additive with function of improving intestinal health of pigs

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20160311

Address after: 514321 Guangdong County of Fengshun province Meizhou City Development Zone, Tang Zhen Hongshi

Patentee after: Meizhou twin Feed Co., Ltd.

Address before: 330096 Nanchang high tech Zone, torch street, No. 999, twins group, Jiangxi

Patentee before: Twins (Group) Co., Ltd.