CN104146182A - Biological feed additive for preventing and treating diarrhoea of piggies - Google Patents
Biological feed additive for preventing and treating diarrhoea of piggies Download PDFInfo
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Abstract
The invention provides a biological feed additive for preventing and treating the diarrhoea of piggies, and belongs to the field of feed additives. The additive consists of composite plant polysaccharide, poria cocos, star anise, ligusticum wallichii, black sesame seeds, catechu, folium et cacumen murrayae, reed rhizomes, composite bacteria, tryptophan, vitamin C, biotin, ferrous fumarate and manganese sulphate carriers, wherein the carriers include peanut shell powder and zeolite powder. The additive is a green, safe and efficient biological feed additive, the diarrhoea of the piggies can be effectively prevented and treated, at the same time, the growing performance of the piggies can be improved, raising cost and breeding risk can be reduced, and the application prospects are quite wide.
Description
Technical field
The present invention relates to a kind of feed addictive, relate in particular to a kind of biology feed additive of preventing and treating grice diarrhoea, belong to feed additive field.
Background technology
Grice diarrhoea is one of principal disease of puzzlement pig industry sound development.Grice diarrhoea can be divided into bacterial diarrhea according to its pathogenic factor, such as: red dysentery, yellow dysentery, dysentery characterized by white mucous stool, dysentery, paratyphoid etc.; Virus diarrhea, such as: pig epidemic diarrhea, pig transmissible stomach and intestine, scorching rotavirus disease etc.; Also have parasitic diarrhea, trophism diarrhea, irritability diarrhoea etc.To effectively take precautions against the generation of grice diarrhoea, must adhere to preventing overweighting the principle of controlling, take the comprehensive measures for the prevention and control of immunity inoculation, strengthen disinfection.Once piglet is suffered from diarrhoea, its intestines and stomach will suffer infringement in various degree, even through treatment recovery from illness, it is normal that the gastrointestinal function of its piglet is also difficult to recover, can directly affect body digesting and assimilating nutriment, thereby cause the price of deed and weightening finish decline in various degree, to pig industry, bring larger economic loss.
For preventing and treating the medicine of grice diarrhoea, be antibiotic formulations the most widely at present.Antibiotic formulations is effective for bacterial diarrhea, but invalid for viral, trophism, irritability diarrhoea, and a large amount of uses not only cause abuse of antibiotics and economic loss, and can make pathogen produce drug resistance, threatens people's health.In the past few decades, antibiotic, as feed addictive application on a large scale in feed industry, at prevention livestock and poultry, promotes growth of animal, improves price of deed aspect and has brought into play indelible effect; Improved greatly the quantity of livestock and poultry and the output of livestock products simultaneously, positive promotion the development of domestic and international animal husbandry, created comparatively considerable economic benefit.But along with antibiotic long-term use, its negative effect of bringing more and more receives people's concern: bacterial drug resistance is more and more stronger, cause animal gastrointestinal tract Dysbiosis, digestive system is disorderly, livestock and poultry immunity of organisms declines, not only reduce the disease-resistant growth-promoting effect to livestock and poultry, also can cause livestock and poultry autogenous infection and suprainfection; Add medicament residue problem simultaneously and not only environment has been caused to huge pollution, also can affect animal products quality the mankind's health is caused to serious harm.Therefore, European Union forbade adding in feed bacitracin, spiramvcin, virginiamycin, 4 kinds of antibiotic of tylosin since 1999; And in 2006, start completely forbid to use antibiotic growth promoter.
That Chinese herbal medicine has is natural, have no side effect,, the feature such as be difficult for develop immunity to drugs residual without chemicals, for preventing and treating grice diarrhoea, is with a wide range of applications.But at present commercially available for preventing and treating the Chinese herbal medicine of grice diarrhoea, result of use is poor, and cure rate is low, and the course for the treatment of is long and cost is high.
Therefore, develop the biology feed additive of a kind of green, efficient, safe effective control grice diarrhoea, there are extraordinary market prospects, the development of our animal husbandry is also had to very large help.
Summary of the invention
The object of the present invention is to provide a kind of green, safety, and can effectively prevent and treat the biology feed additive of grice diarrhoea.
Another object of the present invention is to provide the preparation method of this additive.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A kind of biology feed additive of preventing and treating grice diarrhoea, every 100 parts are comprised of following raw materials by weight portion: composite plant polysaccharide 1-3 part, Poria cocos 4-6 part, Chinese anise 3-5 part, Ligusticum wallichii 4-6 part, Semen sesami nigrum 1-3 part, catechu 2-4 part, kamuning 1-3 part, reed rhizome 2-4 powder, compound bacteria 3-6 part, tryptophan 0.06-0.1 part, vitamin C 0.06-0.1 part, biotin 0.06-0.1 part, ferrous fumarate 0.06-0.1 part, manganese sulfate 0.04-0.08 part, all the other are carrier, carrier by peanut hull meal and zeolite powder in mass ratio 5-7:1 form, peanut shell, zeolite powder was pulverized 40 mesh sieves in advance,
The preparation method of described composite plant polysaccharide is:
(1) by sealwort, lotus seeds, cymose buckwheat rhizome in mass ratio 2-4:3-5:1-3 mix pulverizing, cross 30 mesh sieves, obtain composite plant powder; By composite plant powder and salt in mass ratio 50:3-5 mix, under 55-60 ℃ of condition, temperature is fried 1-2h, temperature is cooled to 25 ℃ after frying and finishing, and then by solid-to-liquid ratio 1:30, adds distilled water, soaks 10 minutes, in immersion process, constantly stir, after immersion finishes, filter, get filter residue, filter residue and drying was pulverized to 30 mesh sieves, must refine composite plant powder;
(2) will refine composite plant powder and complex enzyme in mass ratio 76:1 mix, must contain enzyme Plant Powder; By solid-to-liquid ratio 1:4-8, toward containing adding distil water in enzyme Plant Powder, soak 2-4h, soaking temperature is 55 ℃, after immersion finishes, carries out ultrasonic extraction, and ultrasonic power is 240-260W, and ultrasonic temperature is 85 ℃, and ultrasonic time 15-30 minute filters after ultrasonic end, gets filtrate; Described complex enzyme is cellulase, pectase 3:2 composition in mass ratio;
(3) in the filtrate obtaining toward step (2), add absolute ethyl alcohol, making the concentration of alcohol in solution is 82-87%, and standing 2-4h filters, and gets filtrate, by filtrate freeze drying, pulverizes 60 mesh sieves, obtains composite plant polysaccharide;
Described composite bacterium powder by Bacillus licheniformis powder, lactobacillus fermenti bacterium powder, bifidobacterium infantis bacterium powder, enterococcus faecalis bacterium powder in mass ratio 2-4:1-2:2-3:1-3 form; Wherein in Bacillus licheniformis powder, viable count is 2.8 * 10
10cFU/g, in lactobacillus fermenti bacterium powder, viable count is 1.8 * 10
9cFU/g, in bifidobacterium infantis bacterium powder, viable count is 2.1 * 10
11cFU/g, in enterococcus faecalis bacterium powder, viable count is 3.2 * 10
10cFU/g.
In the present invention, a kind of preparation method of biology feed additive of effective control grice diarrhoea is:
(1) Poria cocos, Chinese anise, Ligusticum wallichii, Semen sesami nigrum, catechu, kamuning, reed rhizome are mixed, pulverized 20 mesh sieves, obtain mixture of Chinese herbal medicines; In mixture of Chinese herbal medicines, by solid-to-liquid ratio 1:0.5, add distilled water, stir, be then placed in freezing 12h under-85 ℃ of conditions, after freezing end, drying and crushing is crossed 60 mesh sieves, stand-by;
(2) by complex polysaccharide, tryptophan, vitamin C, biotin, ferrous fumarate, manganese sulfate, mix with carrier, stand-by;
(3) compound bacteria is mixed with step (1), step (2) gains, obtain product of the present invention.
The addition of product of the present invention in pig starter feed is 300-600 gram/ton.
Beneficial effect
A kind of biology feed additive of preventing and treating grice diarrhoea in the present invention, to carry out on the basis of a large amount of practical applications, according to Chinese traditional herbs, learn, in conjunction with modern farming enterprise's, aetology and immunologic theoretical screening, form, utilize Chinese herbal medicine, natural extract, compound bacteria, vitamin, mineral matter etc. to carry out organic composition, the compatibility association for science and technology, comprehensive nutrition, to regulating, intestine of young pigs is healthy, enhancing pigling immunity has very important effect, effective grice diarrhoea, effective, safely, have no side effect and easy to use; In addition, inventor is in the favorite outer discovery of R&D process, and product of the present invention also has good effect to improving piglet growth performance, has greatly reduced aquaculture cost and cultivation risk.
Specific embodiment
By specific embodiment, further set forth the present invention below.
Embodiment 1
A kind of biology feed additive of preventing and treating grice diarrhoea, every 100 parts are comprised of following raw materials by weight portion: 1 part of composite plant polysaccharide, 4 parts, Poria cocos, 3 parts of Chinese anises, 4 parts of Ligusticum wallichiis, 1 part of Semen sesami nigrum, 2 parts, catechu, 1 part of kamuning, reed rhizome 2 powder, 3 parts of compound bacteria, 0.06 part of tryptophan, 0.06 part of vitamin C, 0.06 part of biotin, 0.06 part of ferrous fumarate, 0.04 part of manganese sulfate, all the other are carrier, carrier by peanut hull meal and zeolite powder in mass ratio 5:1 form, peanut shell, zeolite powder were pulverized 40 mesh sieves in advance;
The preparation method of described composite plant polysaccharide is:
(1) by sealwort, lotus seeds, cymose buckwheat rhizome in mass ratio 2:3-5:1 mix pulverizing, cross 30 mesh sieves, obtain composite plant powder; By composite plant powder and salt in mass ratio 50:3 mix, under 55 ℃ of conditions, temperature is fried 1h, temperature is cooled to 25 ℃ after frying and finishing, and then by solid-to-liquid ratio 1:30, adds distilled water, soaks 10 minutes, in immersion process, constantly stir, after immersion finishes, filter, get filter residue, filter residue and drying was pulverized to 30 mesh sieves, must refine composite plant powder;
(2) will refine composite plant powder and complex enzyme in mass ratio 76:1 mix, must contain enzyme Plant Powder; By solid-to-liquid ratio 1:4, toward containing adding distil water in enzyme Plant Powder, soak 2-4h, soaking temperature is 55 ℃, after immersion finishes, carries out ultrasonic extraction, and ultrasonic power is 240W, and ultrasonic temperature is 85 ℃, and ultrasonic time 15 minutes, filters after ultrasonic end, gets filtrate; Described complex enzyme is cellulase, pectase 3:2 composition in mass ratio;
(3) in the filtrate obtaining toward step (2), add absolute ethyl alcohol, making the concentration of alcohol in solution is 82%, and standing 2h filters, and gets filtrate, by filtrate freeze drying, pulverizes 60 mesh sieves, obtains composite plant polysaccharide;
Described composite bacterium powder by Bacillus licheniformis powder, lactobacillus fermenti bacterium powder, bifidobacterium infantis bacterium powder, enterococcus faecalis bacterium powder in mass ratio 2:1:2:1 form; Wherein in Bacillus licheniformis powder, viable count is 2.8 * 10
10cFU/g, in lactobacillus fermenti bacterium powder, viable count is 1.8 * 10
9cFU/g, in bifidobacterium infantis bacterium powder, viable count is 2.1 * 10
11cFU/g, in enterococcus faecalis bacterium powder, viable count is 3.2 * 10
10cFU/g.
In the present invention, a kind of preparation method of biology feed additive of effective control grice diarrhoea is:
(1) Poria cocos, Chinese anise, Ligusticum wallichii, Semen sesami nigrum, catechu, kamuning, reed rhizome are mixed, pulverized 20 mesh sieves, obtain mixture of Chinese herbal medicines; In mixture of Chinese herbal medicines, by solid-to-liquid ratio 1:0.5, add distilled water, stir, be then placed in freezing 12h under-85 ℃ of conditions, after freezing end, drying and crushing is crossed 60 mesh sieves, stand-by;
(2) by complex polysaccharide, tryptophan, vitamin C, biotin, ferrous fumarate, manganese sulfate, mix with carrier, stand-by;
(3) compound bacteria is mixed with step (1), step (2) gains, obtain product of the present invention.
The addition of product of the present invention in pig starter feed is 300 grams/ton.
Embodiment 2
A kind of biology feed additive of preventing and treating grice diarrhoea, every 100 parts are comprised of following raw materials by weight portion: 2 parts of composite plant polysaccharide, 5 parts, Poria cocos, 4 parts of Chinese anises, 5 parts of Ligusticum wallichiis, 2 parts of Semen sesami nigrums, 3 parts, catechu, 2 parts of kamuning, reed rhizome 3 powder, 5 parts of compound bacteria, 0.08 part of tryptophan, 0.08 part of vitamin C, 0.08 part of biotin, 0.08 part of ferrous fumarate, 0.06 part of manganese sulfate, all the other are carrier, carrier by peanut hull meal and zeolite powder in mass ratio 6:1 form, peanut shell, zeolite powder were pulverized 40 mesh sieves in advance;
The preparation method of described composite plant polysaccharide is:
(1) by sealwort, lotus seeds, cymose buckwheat rhizome in mass ratio 3:4:2 mix pulverizing, cross 30 mesh sieves, obtain composite plant powder; By composite plant powder and salt in mass ratio 50:4 mix, under 58 ℃ of conditions, temperature is fried 1.5h, temperature is cooled to 25 ℃ after frying and finishing, and then by solid-to-liquid ratio 1:30, adds distilled water, soaks 10 minutes, in immersion process, constantly stir, after immersion finishes, filter, get filter residue, filter residue and drying was pulverized to 30 mesh sieves, must refine composite plant powder;
(2) will refine composite plant powder and complex enzyme in mass ratio 76:1 mix, must contain enzyme Plant Powder; By solid-to-liquid ratio 1:6, toward containing adding distil water in enzyme Plant Powder, soak 3h, soaking temperature is 55 ℃, after immersion finishes, carries out ultrasonic extraction, and ultrasonic power is 250W, and ultrasonic temperature is 85 ℃, and ultrasonic time 20 minutes, filters after ultrasonic end, gets filtrate; Described complex enzyme is cellulase, pectase 3:2 composition in mass ratio;
(3) in the filtrate obtaining toward step (2), add absolute ethyl alcohol, making the concentration of alcohol in solution is 85%, and standing 3h filters, and gets filtrate, by filtrate freeze drying, pulverizes 60 mesh sieves, obtains composite plant polysaccharide;
Described composite bacterium powder by Bacillus licheniformis powder, lactobacillus fermenti bacterium powder, bifidobacterium infantis bacterium powder, enterococcus faecalis bacterium powder in mass ratio 3:2:3:2 form; Wherein in Bacillus licheniformis powder, viable count is 2.8 * 10
10cFU/g, in lactobacillus fermenti bacterium powder, viable count is 1.8 * 10
9cFU/g, in bifidobacterium infantis bacterium powder, viable count is 2.1 * 10
11cFU/g, in enterococcus faecalis bacterium powder, viable count is 3.2 * 10
10cFU/g.
In the present invention, a kind of preparation method of biology feed additive of effective control grice diarrhoea is:
(1) Poria cocos, Chinese anise, Ligusticum wallichii, Semen sesami nigrum, catechu, kamuning, reed rhizome are mixed, pulverized 20 mesh sieves, obtain mixture of Chinese herbal medicines; In mixture of Chinese herbal medicines, by solid-to-liquid ratio 1:0.5, add distilled water, stir, be then placed in freezing 12h under-85 ℃ of conditions, after freezing end, drying and crushing is crossed 60 mesh sieves, stand-by;
(2) by complex polysaccharide, tryptophan, vitamin C, biotin, ferrous fumarate, manganese sulfate, mix with carrier, stand-by;
(3) compound bacteria is mixed with step (1), step (2) gains, obtain product of the present invention.
The addition of product of the present invention in pig starter feed is 450 grams/ton.
Embodiment 3
A kind of biology feed additive of preventing and treating grice diarrhoea, every 100 parts are comprised of following raw materials by weight portion: 3 parts of composite plant polysaccharide, 6 parts, Poria cocos, 5 parts of Chinese anises, 6 parts of Ligusticum wallichiis, 3 parts of Semen sesami nigrums, 4 parts, catechu, 3 parts of kamuning, reed rhizome 4 powder, 6 parts of compound bacteria, 0.1 part of tryptophan, 0.1 part of vitamin C, 0.1 part of biotin, 0.1 part of ferrous fumarate, 0.08 part of manganese sulfate, all the other are carrier, carrier by peanut hull meal and zeolite powder in mass ratio 7:1 form, peanut shell, zeolite powder were pulverized 40 mesh sieves in advance;
The preparation method of described composite plant polysaccharide is:
(1) by sealwort, lotus seeds, cymose buckwheat rhizome in mass ratio 4:5:3 mix pulverizing, cross 30 mesh sieves, obtain composite plant powder; By composite plant powder and salt in mass ratio 50:5 mix, under 60 ℃ of conditions, temperature is fried 2h, temperature is cooled to 25 ℃ after frying and finishing, and then by solid-to-liquid ratio 1:30, adds distilled water, soaks 10 minutes, in immersion process, constantly stir, after immersion finishes, filter, get filter residue, filter residue and drying was pulverized to 30 mesh sieves, must refine composite plant powder;
(2) will refine composite plant powder and complex enzyme in mass ratio 76:1 mix, must contain enzyme Plant Powder; By solid-to-liquid ratio 1:8, toward containing adding distil water in enzyme Plant Powder, soak 4h, soaking temperature is 55 ℃, after immersion finishes, carries out ultrasonic extraction, and ultrasonic power is 260W, and ultrasonic temperature is 85 ℃, and ultrasonic time 30 minutes, filters after ultrasonic end, gets filtrate; Described complex enzyme is cellulase, pectase 3:2 composition in mass ratio;
(3) in the filtrate obtaining toward step (2), add absolute ethyl alcohol, making the concentration of alcohol in solution is 87%, and standing 4h filters, and gets filtrate, by filtrate freeze drying, pulverizes 60 mesh sieves, obtains composite plant polysaccharide;
Described composite bacterium powder by Bacillus licheniformis powder, lactobacillus fermenti bacterium powder, bifidobacterium infantis bacterium powder, enterococcus faecalis bacterium powder in mass ratio 4:2:3:3 form; Wherein in Bacillus licheniformis powder, viable count is 2.8 * 10
10cFU/g, in lactobacillus fermenti bacterium powder, viable count is 1.8 * 10
9cFU/g, in bifidobacterium infantis bacterium powder, viable count is 2.1 * 10
11cFU/g, in enterococcus faecalis bacterium powder, viable count is 3.2 * 10
10cFU/g.
In the present invention, a kind of preparation method of biology feed additive of effective control grice diarrhoea is:
(1) Poria cocos, Chinese anise, Ligusticum wallichii, Semen sesami nigrum, catechu, kamuning, reed rhizome are mixed, pulverized 20 mesh sieves, obtain mixture of Chinese herbal medicines; In mixture of Chinese herbal medicines, by solid-to-liquid ratio 1:0.5, add distilled water, stir, be then placed in freezing 12h under-85 ℃ of conditions, after freezing end, drying and crushing is crossed 60 mesh sieves, stand-by;
(2) by complex polysaccharide, tryptophan, vitamin C, biotin, ferrous fumarate, manganese sulfate, mix with carrier, stand-by;
(3) compound bacteria is mixed with step (1), step (2) gains, obtain product of the present invention.
The addition of product of the present invention in pig starter feed is 600 grams/ton.
Embodiment 4
A kind of biology feed additive of preventing and treating grice diarrhoea, every 100 parts are comprised of following raw materials by weight portion: 1 part of composite plant polysaccharide, 1 part, Poria cocos, 1 part of Chinese anise, 2 parts of Ligusticum wallichiis, 1 part of Semen sesami nigrum, 1 part, catechu, 1 part of kamuning, reed rhizome 1 powder, 1 part of compound bacteria, 0.02 part of tryptophan, 0.02 part of vitamin C, 0.01 part of biotin, 0.01 part of ferrous fumarate, 0.01 part of manganese sulfate, all the other are carrier, carrier by peanut hull meal and zeolite powder in mass ratio 1:1 form, peanut shell, zeolite powder were pulverized 40 mesh sieves in advance;
All the other are with embodiment 2.
Experimental example 1
300 of the sodium selenites that test selection Chengdu subordinate plant of twins feed corporation,Ltd average weight is 8.1kg, statistical analysis body weight difference is not remarkable.Be divided at random 5 groups (4 test group and 1 control group), every group of 6 repetitions, each repeats 10, male and female half and half.In control group daily ration, do not add the additive of any enhancing pig immunity making in embodiment 1-4, in test group daily ration, add respectively the additive that embodiment 1-4 makes, piglet free choice feeding and drinking-water, carry out routinely immunity and expelling parasite, in experimental period, observe and record the diarrhoea situation of piglet every day, totally 30 days experimental period.
Result of the test is as follows:
Conclusion (of pressure testing): can be found out by above result of the test, feed addictive of the present invention can effectively reduce grice diarrhoea rate, to improving the daily gain of piglet, has reduced feedstuff-meat ratio and has had good effect simultaneously, can effectively save feeding cost, there is good marketing prospect.
Experimental example 2
Select 80 of piglets of diarrhoea, be equally divided at random 2 groups, the test group feed of the additive that contains embodiment 2 preparations of feeding wherein, control group adopts conventional western medicine; Test pig free choice feeding and drinking-water, observe and record rehabilitation situation and the mental status of pig, totally 30 days experimental period in experimental period every day.During off-test, weigh, and ramming material.Observe each processed group diarrhoea situation, and calculate daily gain, feedstuff-meat ratio (feed intake/weightening finish) and rehabilitation rate.
Result of the test shows that product of the present invention treatment grice diarrhoea effect is suitable with Western medicine, but daily gain is apparently higher than control group, and feedstuff-meat ratio significantly reduces, and is conducive to reduce feeding cost, increase culture benefit.Product of the present invention belongs to green product simultaneously, does not exist residual and causes drug resistance equivalent risk, and this is the advantage that Western medicine does not possess completely.
Claims (5)
1. a biology feed additive of preventing and treating grice diarrhoea, it is characterized in that every 100 parts are comprised of following raw materials by weight portion: composite plant polysaccharide 1-3 part, Poria cocos 4-6 part, Chinese anise 3-5 part, Ligusticum wallichii 4-6 part, Semen sesami nigrum 1-3 part, catechu 2-4 part, kamuning 1-3 part, reed rhizome 2-4 powder, compound bacteria 3-6 part, tryptophan 0.06-0.1 part, vitamin C 0.06-0.1 part, biotin 0.06-0.1 part, ferrous fumarate 0.06-0.1 part, manganese sulfate 0.04-0.08 part, all the other are carrier, carrier by peanut hull meal and zeolite powder in mass ratio 5-7:1 form, peanut shell, zeolite powder was pulverized 40 mesh sieves in advance,
The preparation method of described composite plant polysaccharide is:
(1) by sealwort, lotus seeds, cymose buckwheat rhizome in mass ratio 2-4:3-5:1-3 mix pulverizing, cross 30 mesh sieves, obtain composite plant powder; By composite plant powder and salt in mass ratio 50:3-5 mix, under 55-60 ℃ of condition, temperature is fried 1-2h, temperature is cooled to 25 ℃ after frying and finishing, and then by solid-to-liquid ratio 1:30, adds distilled water, soaks 10 minutes, in immersion process, constantly stir, after immersion finishes, filter, get filter residue, filter residue and drying was pulverized to 30 mesh sieves, must refine composite plant powder;
(2) will refine composite plant powder and complex enzyme in mass ratio 76:1 mix, must contain enzyme Plant Powder; By solid-to-liquid ratio 1:4-8, toward containing adding distil water in enzyme Plant Powder, soak 2-4h, soaking temperature is 55 ℃, after immersion finishes, carries out ultrasonic extraction, and ultrasonic power is 240-260W, and ultrasonic temperature is 85 ℃, and ultrasonic time 15-30 minute filters after ultrasonic end, gets filtrate; Described complex enzyme is cellulase, pectase 3:2 composition in mass ratio;
(3) in the filtrate obtaining toward step (2), add absolute ethyl alcohol, making the concentration of alcohol in solution is 82-87%, and standing 2-4h filters, and gets filtrate, by filtrate freeze drying, pulverizes 60 mesh sieves, obtains composite plant polysaccharide;
Described composite bacterium powder by Bacillus licheniformis powder, lactobacillus fermenti bacterium powder, bifidobacterium infantis bacterium powder, enterococcus faecalis bacterium powder in mass ratio 2-4:1-2:2-3:1-3 form; Wherein in Bacillus licheniformis powder, viable count is 2.8 * 10
10cFU/g, in lactobacillus fermenti bacterium powder, viable count is 1.8 * 10
9cFU/g, in bifidobacterium infantis bacterium powder, viable count is 2.1 * 10
11cFU/g, in enterococcus faecalis bacterium powder, viable count is 3.2 * 10
10cFU/g.
2. a kind of biology feed additive of effective control grice diarrhoea according to claim 1, it is characterized in that every 100 parts are comprised of following raw materials by weight portion: 2 parts of composite plant polysaccharide, 5 parts, Poria cocos, 4 parts of Chinese anises, 5 parts of Ligusticum wallichiis, 2 parts of Semen sesami nigrums, 3 parts, catechu, 2 parts of kamuning, reed rhizome 3 powder, 5 parts of compound bacteria, 0.08 part of tryptophan, 0.08 part of vitamin C, 0.08 part of biotin, 0.08 part of ferrous fumarate, 0.06 part of manganese sulfate, all the other are carrier, carrier by peanut hull meal and zeolite powder in mass ratio 6:1 form, peanut shell, zeolite powder was pulverized 40 mesh sieves in advance,
The preparation method of described composite plant polysaccharide is:
(1) by sealwort, lotus seeds, cymose buckwheat rhizome in mass ratio 3:4:2 mix pulverizing, cross 30 mesh sieves, obtain composite plant powder; By composite plant powder and salt in mass ratio 50:4 mix, under 58 ℃ of conditions, temperature is fried 1.5h, temperature is cooled to 25 ℃ after frying and finishing, and then by solid-to-liquid ratio 1:30, adds distilled water, soaks 10 minutes, in immersion process, constantly stir, after immersion finishes, filter, get filter residue, filter residue and drying was pulverized to 30 mesh sieves, must refine composite plant powder;
(2) will refine composite plant powder and complex enzyme in mass ratio 76:1 mix, must contain enzyme Plant Powder; By solid-to-liquid ratio 1:6, toward containing adding distil water in enzyme Plant Powder, soak 3h, soaking temperature is 55 ℃, after immersion finishes, carries out ultrasonic extraction, and ultrasonic power is 250W, and ultrasonic temperature is 85 ℃, and ultrasonic time 20 minutes, filters after ultrasonic end, gets filtrate; Described complex enzyme is cellulase, pectase 3:2 composition in mass ratio;
(3) in the filtrate obtaining toward step (2), add absolute ethyl alcohol, making the concentration of alcohol in solution is 85%, and standing 3h filters, and gets filtrate, by filtrate freeze drying, pulverizes 60 mesh sieves, obtains composite plant polysaccharide;
Described composite bacterium powder by Bacillus licheniformis powder, lactobacillus fermenti bacterium powder, bifidobacterium infantis bacterium powder, enterococcus faecalis bacterium powder in mass ratio 3:2:3:2 form; Wherein in Bacillus licheniformis powder, viable count is 2.8 * 10
10cFU/g, in lactobacillus fermenti bacterium powder, viable count is 1.8 * 10
9cFU/g, in bifidobacterium infantis bacterium powder, viable count is 2.1 * 10
11cFU/g, in enterococcus faecalis bacterium powder, viable count is 3.2 * 10
10cFU/g.
3. according to the biology feed additive of a kind of effective control grice diarrhoea described in claim 1 or 2, it is characterized in that preparation method is:
(1) Poria cocos, Chinese anise, Ligusticum wallichii, Semen sesami nigrum, catechu, kamuning, reed rhizome are mixed, pulverized 20 mesh sieves, obtain mixture of Chinese herbal medicines; In mixture of Chinese herbal medicines, by solid-to-liquid ratio 1:0.5, add distilled water, stir, be then placed in freezing 12h under-85 ℃ of conditions, after freezing end, drying and crushing is crossed 60 mesh sieves, stand-by;
(2) by complex polysaccharide, tryptophan, vitamin C, biotin, ferrous fumarate, manganese sulfate, mix with carrier, stand-by;
(3) compound bacteria is mixed with step (1), step (2) gains, obtain.
4. according to the biology feed additive of a kind of effective control grice diarrhoea described in claim 1 or 2, it is characterized in that the addition in pig starter feed is 300-600 gram/ton.
5. according to the biology feed additive of a kind of effective control grice diarrhoea described in claim 1 or 2, it is characterized in that the addition in pig starter feed is 450 grams/ton.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104489420A (en) * | 2015-01-20 | 2015-04-08 | 清远市江丰饲料有限公司 | Pig feed additive capable of booting immunity and improving meat quality |
| CN105309809A (en) * | 2015-11-30 | 2016-02-10 | 大理双胞胎饲料有限公司 | Novel green feed additive for pigs |
| CN105410412A (en) * | 2015-12-30 | 2016-03-23 | 双胞胎（集团）股份有限公司 | Green high-efficiency pig Chinese herbal medicine feed additive |
| CN105410413A (en) * | 2015-12-30 | 2016-03-23 | 双胞胎（集团）股份有限公司 | Feed additive for pigs and promoting growth and raising pork quality |
| CN105454661A (en) * | 2015-12-30 | 2016-04-06 | 双胞胎（集团）股份有限公司 | Pig feed additive for enhancing immunity |
| CN105475635A (en) * | 2016-02-01 | 2016-04-13 | 广南(湛江)家丰饲料有限公司 | Biological feed additive which is used for pigs and can replace antibiotics |
| CN105558378A (en) * | 2015-12-30 | 2016-05-11 | 双胞胎（集团）股份有限公司 | Feed additive with effects in enhancing pig immunity and protecting nutrient components in feed |
| CN105614102A (en) * | 2015-12-30 | 2016-06-01 | 双胞胎（集团）股份有限公司 | Pig feed additive for improving immunity and improving intestinal health |
| CN105639099A (en) * | 2015-12-30 | 2016-06-08 | 双胞胎（集团）股份有限公司 | Pig feed additive for improving intestinal health |
| CN105961864A (en) * | 2016-05-05 | 2016-09-28 | 张艳艳 | Antibiotic-free piggy feed capable of preventing and treating diarrhoea and preparation method of antibiotic-free piggy feed |
| CN106615818A (en) * | 2016-12-30 | 2017-05-10 | 中悦民安（北京）科技发展有限公司 | Piglet premixed feed for relieving diarrhea with astringents and preparation method thereof |
| CN106798115A (en) * | 2015-11-26 | 2017-06-06 | 长沙为民生物科技有限公司 | A kind of feed addictive for pig |
| CN107167558A (en) * | 2017-05-22 | 2017-09-15 | 深圳市金新农科技股份有限公司 | A kind of additive agent for feeding replace anti-performance appraisal procedure |
| CN108142641A (en) * | 2018-03-07 | 2018-06-12 | 余姚辉农农业科技有限公司 | A kind of pig starter feed of piglet with natural ferment and comprising the ferment |
| CN110024909A (en) * | 2019-04-24 | 2019-07-19 | 贵州中宝药业有限公司 | Feeding natural vegetable Chinese herbal medicine is for anti-additive and preparation method thereof |
| CN116286496A (en) * | 2023-02-19 | 2023-06-23 | 浙江大学 | Composite probiotics for reducing diarrhea of weaned pigs and application thereof |
| CN117179168A (en) * | 2023-02-16 | 2023-12-08 | 贵州省畜牧兽医研究所 | Local pig feed based on wild buckwheat rhizome fermented product in Qian and preparation method thereof |
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| CN104489420A (en) * | 2015-01-20 | 2015-04-08 | 清远市江丰饲料有限公司 | Pig feed additive capable of booting immunity and improving meat quality |
| CN106798115A (en) * | 2015-11-26 | 2017-06-06 | 长沙为民生物科技有限公司 | A kind of feed addictive for pig |
| CN105309809A (en) * | 2015-11-30 | 2016-02-10 | 大理双胞胎饲料有限公司 | Novel green feed additive for pigs |
| CN105639099A (en) * | 2015-12-30 | 2016-06-08 | 双胞胎（集团）股份有限公司 | Pig feed additive for improving intestinal health |
| CN105410412A (en) * | 2015-12-30 | 2016-03-23 | 双胞胎（集团）股份有限公司 | Green high-efficiency pig Chinese herbal medicine feed additive |
| CN105558378A (en) * | 2015-12-30 | 2016-05-11 | 双胞胎（集团）股份有限公司 | Feed additive with effects in enhancing pig immunity and protecting nutrient components in feed |
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| CN105410413A (en) * | 2015-12-30 | 2016-03-23 | 双胞胎（集团）股份有限公司 | Feed additive for pigs and promoting growth and raising pork quality |
| CN105454661A (en) * | 2015-12-30 | 2016-04-06 | 双胞胎（集团）股份有限公司 | Pig feed additive for enhancing immunity |
| CN105475635A (en) * | 2016-02-01 | 2016-04-13 | 广南(湛江)家丰饲料有限公司 | Biological feed additive which is used for pigs and can replace antibiotics |
| CN105961864A (en) * | 2016-05-05 | 2016-09-28 | 张艳艳 | Antibiotic-free piggy feed capable of preventing and treating diarrhoea and preparation method of antibiotic-free piggy feed |
| CN106615818A (en) * | 2016-12-30 | 2017-05-10 | 中悦民安（北京）科技发展有限公司 | Piglet premixed feed for relieving diarrhea with astringents and preparation method thereof |
| CN107167558A (en) * | 2017-05-22 | 2017-09-15 | 深圳市金新农科技股份有限公司 | A kind of additive agent for feeding replace anti-performance appraisal procedure |
| CN108142641A (en) * | 2018-03-07 | 2018-06-12 | 余姚辉农农业科技有限公司 | A kind of pig starter feed of piglet with natural ferment and comprising the ferment |
| CN110024909A (en) * | 2019-04-24 | 2019-07-19 | 贵州中宝药业有限公司 | Feeding natural vegetable Chinese herbal medicine is for anti-additive and preparation method thereof |
| CN117179168A (en) * | 2023-02-16 | 2023-12-08 | 贵州省畜牧兽医研究所 | Local pig feed based on wild buckwheat rhizome fermented product in Qian and preparation method thereof |
| CN116286496A (en) * | 2023-02-19 | 2023-06-23 | 浙江大学 | Composite probiotics for reducing diarrhea of weaned pigs and application thereof |
| CN116286496B (en) * | 2023-02-19 | 2023-11-14 | 浙江大学 | Composite probiotics for reducing diarrhea of weaned pigs and application thereof |
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Effective date of registration: 20160908 Address after: 514321 Guangdong County of Fengshun province Meizhou City Development Zone, Tang Zhen Hongshi Patentee after: Meizhou twin Feed Co., Ltd. Address before: 611430 Chengdu twin Feed Co., Ltd. Xinjin Chengdu Sichuan cooperation Industrial Park, Sichuan Province Patentee before: CHENGDU TWINS FEED CO., LTD. |